Last updated: 2023-11-17
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Knit directory: myproject/
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REQUIRED Libraries
library(EDASeq)Loading required package: BiobaseLoading required package: BiocGenerics
Attaching package: 'BiocGenerics'The following objects are masked from 'package:stats':
IQR, mad, sd, var, xtabsThe following objects are masked from 'package:base':
anyDuplicated, append, as.data.frame, basename, cbind, colnames,
dirname, do.call, duplicated, eval, evalq, Filter, Find, get, grep,
grepl, intersect, is.unsorted, lapply, Map, mapply, match, mget,
order, paste, pmax, pmax.int, pmin, pmin.int, Position, rank,
rbind, Reduce, rownames, sapply, setdiff, sort, table, tapply,
union, unique, unsplit, which.max, which.minWelcome to Bioconductor
Vignettes contain introductory material; view with
'browseVignettes()'. To cite Bioconductor, see
'citation("Biobase")', and for packages 'citation("pkgname")'.Loading required package: ShortReadLoading required package: BiocParallelWarning: package 'BiocParallel' was built under R version 4.2.1Loading required package: BiostringsWarning: package 'Biostrings' was built under R version 4.2.1Loading required package: S4VectorsLoading required package: stats4
Attaching package: 'S4Vectors'The following objects are masked from 'package:base':
expand.grid, I, unnameLoading required package: IRangesWarning: package 'IRanges' was built under R version 4.2.1Loading required package: XVectorLoading required package: GenomeInfoDbWarning: package 'GenomeInfoDb' was built under R version 4.2.1
Attaching package: 'Biostrings'The following object is masked from 'package:base':
strsplitLoading required package: RsamtoolsLoading required package: GenomicRangesLoading required package: GenomicAlignmentsWarning: package 'GenomicAlignments' was built under R version 4.2.1Loading required package: SummarizedExperimentLoading required package: MatrixGenericsLoading required package: matrixStats
Attaching package: 'matrixStats'The following objects are masked from 'package:Biobase':
anyMissing, rowMedians
Attaching package: 'MatrixGenerics'The following objects are masked from 'package:matrixStats':
colAlls, colAnyNAs, colAnys, colAvgsPerRowSet, colCollapse,
colCounts, colCummaxs, colCummins, colCumprods, colCumsums,
colDiffs, colIQRDiffs, colIQRs, colLogSumExps, colMadDiffs,
colMads, colMaxs, colMeans2, colMedians, colMins, colOrderStats,
colProds, colQuantiles, colRanges, colRanks, colSdDiffs, colSds,
colSums2, colTabulates, colVarDiffs, colVars, colWeightedMads,
colWeightedMeans, colWeightedMedians, colWeightedSds,
colWeightedVars, rowAlls, rowAnyNAs, rowAnys, rowAvgsPerColSet,
rowCollapse, rowCounts, rowCummaxs, rowCummins, rowCumprods,
rowCumsums, rowDiffs, rowIQRDiffs, rowIQRs, rowLogSumExps,
rowMadDiffs, rowMads, rowMaxs, rowMeans2, rowMedians, rowMins,
rowOrderStats, rowProds, rowQuantiles, rowRanges, rowRanks,
rowSdDiffs, rowSds, rowSums2, rowTabulates, rowVarDiffs, rowVars,
rowWeightedMads, rowWeightedMeans, rowWeightedMedians,
rowWeightedSds, rowWeightedVarsThe following object is masked from 'package:Biobase':
rowMedianslibrary(RUVSeq)Loading required package: edgeRWarning: package 'edgeR' was built under R version 4.2.1Loading required package: limmaWarning: package 'limma' was built under R version 4.2.1
Attaching package: 'limma'The following object is masked from 'package:BiocGenerics':
plotMAlibrary(RColorBrewer)
library(edgeR)
library(limma)
library(Biobase)
library(SummarizedExperiment)
library(tidyverse) ── Attaching core tidyverse packages ──────────────────────── tidyverse 2.0.0 ──
✔ dplyr 1.1.2 ✔ readr 2.1.4
✔ forcats 1.0.0 ✔ stringr 1.5.0
✔ ggplot2 3.4.3 ✔ tibble 3.2.1
✔ lubridate 1.9.2 ✔ tidyr 1.3.0
✔ purrr 1.0.2 ── Conflicts ────────────────────────────────────────── tidyverse_conflicts() ──
✖ lubridate::%within%() masks IRanges::%within%()
✖ dplyr::collapse() masks Biostrings::collapse(), IRanges::collapse()
✖ dplyr::combine() masks Biobase::combine(), BiocGenerics::combine()
✖ purrr::compact() masks XVector::compact()
✖ purrr::compose() masks ShortRead::compose()
✖ dplyr::count() masks matrixStats::count()
✖ dplyr::desc() masks IRanges::desc()
✖ tidyr::expand() masks S4Vectors::expand()
✖ dplyr::filter() masks stats::filter()
✖ dplyr::first() masks GenomicAlignments::first(), S4Vectors::first()
✖ dplyr::id() masks ShortRead::id()
✖ dplyr::lag() masks stats::lag()
✖ dplyr::last() masks GenomicAlignments::last()
✖ ggplot2::Position() masks BiocGenerics::Position(), base::Position()
✖ purrr::reduce() masks GenomicRanges::reduce(), IRanges::reduce()
✖ dplyr::rename() masks S4Vectors::rename()
✖ lubridate::second() masks GenomicAlignments::second(), S4Vectors::second()
✖ lubridate::second<-() masks S4Vectors::second<-()
✖ dplyr::slice() masks XVector::slice(), IRanges::slice()
✖ tibble::view() masks ShortRead::view()
ℹ Use the conflicted package (<http://conflicted.r-lib.org/>) to force all conflicts to become errorslibrary(ggfortify)
library(cluster)
library(edgeR)
library(limma)
library(biomaRt)
library(Homo.sapiens)Loading required package: AnnotationDbi
Attaching package: 'AnnotationDbi'
The following object is masked from 'package:dplyr':
select
Loading required package: OrganismDbi
Loading required package: GenomicFeaturesWarning: package 'GenomicFeatures' was built under R version 4.2.1Loading required package: GO.db
Loading required package: org.Hs.eg.db
Loading required package: TxDb.Hsapiens.UCSC.hg19.knownGenelibrary(BiocParallel)
library(qvalue)
library(pheatmap)
library(clusterProfiler)Registered S3 methods overwritten by 'treeio':
method from
MRCA.phylo tidytree
MRCA.treedata tidytree
Nnode.treedata tidytree
Ntip.treedata tidytree
ancestor.phylo tidytree
ancestor.treedata tidytree
child.phylo tidytree
child.treedata tidytree
full_join.phylo tidytree
full_join.treedata tidytree
groupClade.phylo tidytree
groupClade.treedata tidytree
groupOTU.phylo tidytree
groupOTU.treedata tidytree
is.rooted.treedata tidytree
nodeid.phylo tidytree
nodeid.treedata tidytree
nodelab.phylo tidytree
nodelab.treedata tidytree
offspring.phylo tidytree
offspring.treedata tidytree
parent.phylo tidytree
parent.treedata tidytree
root.treedata tidytree
rootnode.phylo tidytree
sibling.phylo tidytree
clusterProfiler v4.4.4 For help: https://yulab-smu.top/biomedical-knowledge-mining-book/
If you use clusterProfiler in published research, please cite:
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu. clusterProfiler 4.0: A universal enrichment tool for interpreting omics data. The Innovation. 2021, 2(3):100141
Attaching package: 'clusterProfiler'
The following object is masked from 'package:OrganismDbi':
select
The following object is masked from 'package:AnnotationDbi':
select
The following object is masked from 'package:biomaRt':
select
The following object is masked from 'package:purrr':
simplify
The following object is masked from 'package:XVector':
slice
The following object is masked from 'package:IRanges':
slice
The following object is masked from 'package:S4Vectors':
rename
The following object is masked from 'package:stats':
filterlibrary(AnnotationDbi)
library(org.Hs.eg.db)
library(RColorBrewer)
library(DOSE)Warning: package 'DOSE' was built under R version 4.2.1DOSE v3.22.1 For help: https://yulab-smu.top/biomedical-knowledge-mining-book/
If you use DOSE in published research, please cite:
Guangchuang Yu, Li-Gen Wang, Guang-Rong Yan, Qing-Yu He. DOSE: an R/Bioconductor package for Disease Ontology Semantic and Enrichment analysis. Bioinformatics 2015, 31(4):608-609library(UpSetR)
library(ggvenn)Loading required package: grid
Attaching package: 'grid'
The following object is masked from 'package:Biostrings':
patternRead in Data
Load your data
Protein_DF <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Data_Frames/Abundance.csv", header = TRUE)
Meta <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Data_Frames/Meta.csv", header = TRUE)Wrangle Data Frame
Save the original
Full_DF <- Protein_DF Subset the columns referring to abundance
Protein_DF_Abundance <- Protein_DF[,c(4, 5:ncol(Protein_DF))] Check for duplicated rows
Identify duplicated values
Protein_DF_Abundance$duplicated_name <- duplicated(Protein_DF_Abundance$Accession)This will return a logical vector where TRUE indicates the position of duplicates in the column.
To see only rows with duplicated values, you can subset the dataframe like this:
duplicated_rows <- Protein_DF_Abundance[Protein_DF_Abundance$duplicated_name == TRUE, ]
print(duplicated_rows) Accession Abundance..F1..Sample..Dox..n.a Abundance..F3..Sample..Dox..n.a
61 P04264 3.87e+08 1.45e+08
276 P35908 NA NA
997 P04040 NA NA
Abundance..F5..Sample..Dox..Dox Abundance..F7..Sample..Dox..Dox
61 2.58e+08 7.07e+08
276 NA NA
997 NA NA
Abundance..F9..Sample..Dox..Dox Abundance..F2..Control..Veh..n.a
61 3.17e+08 1.19e+10
276 NA 5.31e+06
997 NA NA
Abundance..F4..Control..Veh..n.a Abundance..F6..Control..Veh..Veh
61 1.11e+09 8.03e+08
276 1.14e+06 NA
997 NA NA
Abundance..F8..Control..Veh..Veh Abundance..F10..Control..Veh..Veh
61 4.61e+08 5.45e+08
276 5.00e+05 4.90e+05
997 NA NA
duplicated_name
61 TRUE
276 TRUE
997 TRUEWe have 3 rows with duplicates, two of which have NA values. We will remove them now since we will go ahead
and remove the duplicated rows later on anyways.
Protein_DF_Abundance <- Protein_DF_Abundance[- c(61, 276, 997), ] Make rownames of the data frame accession IDs
rownames(Protein_DF_Abundance) <- Protein_DF_Abundance$Accession
# Change colnames
colnames(Protein_DF_Abundance) [1] "Accession" "Abundance..F1..Sample..Dox..n.a"
[3] "Abundance..F3..Sample..Dox..n.a" "Abundance..F5..Sample..Dox..Dox"
[5] "Abundance..F7..Sample..Dox..Dox" "Abundance..F9..Sample..Dox..Dox"
[7] "Abundance..F2..Control..Veh..n.a" "Abundance..F4..Control..Veh..n.a"
[9] "Abundance..F6..Control..Veh..Veh" "Abundance..F8..Control..Veh..Veh"
[11] "Abundance..F10..Control..Veh..Veh" "duplicated_name" Protein_DF_Abundance <- Protein_DF_Abundance[, -c(1, 12)]
# Assuming column names of Protein_DF match with the rows in Meta
rownames(Meta) <- Meta$Samples
colnames(Protein_DF_Abundance) <- Meta$SamplesRemove rows with at least one NA
#1. Find rows with any NA values
rows_with_na <- apply(Protein_DF_Abundance, 1, function(x) any(is.na(x))) %>% which()
rows_with_na Q9Y623 A7E2Y1 Q562R1 A5A3E0 P04350 Q9H6N6 Q9BVA1
12 39 41 49 124 129 135
P54652 Q5QNW6 O60814 P49448 Q08043 Q02539 P05976
197 200 215 224 232 296 320
P35749 P04259 O00148 O15020 P08134 P52790 P0C7P4
353 396 484 497 506 541 565
Q2TB90 Q9ULD0 P26232 Q01814 P19012 Q92930 P07205
570 707 718 733 846 881 912
Q5TFQ8 Q8IUE6 Q9H254 Q6P2I3 Q9H361 P84085 Q14690
967 1018 1053 1126 1182 1204 1254
Q5XKE5 Q7Z3Y8 P13746 P19013 P41219 Q14194 P62714
1290 1328 1357 1382 1428 1437 1444
Q14568 P16157 Q15771 P57721 Q13555 P42025 Q2M2I5
1451 1486 1498 1532 1534 1564 1565
Q8IZP2 P01892 Q9BY77 P15153 Q6KB66 O95758 O14787
1630 1633 1648 1654 1747 1762 1768
Q9BXF3 A6NHQ2 P27361 Q9NYU1 Q03113 Q16352 P18463
1827 1847 1892 1916 1925 1938 1972
Q8N1N4 P21817 O60282 O00160 Q9UM54 Q13501 Q12840
2000 2007 2025 2035 2036 2038 2098
Q8WXI9 P04222 P01116 P51805 P61225 Q16799 O60784
2100 2111 2118 2147 2150 2156 2165
Q9P0S3 P10114 Q15437 Q9NRR5 O94788 P12036 Q92901
2167 2169 2201 2206 2218 2221 2227
Q9BYC2 Q05193 Q02413 Q9UKN7 Q96IX5 Q13948 O43432
2235 2239 2244 2247 2271 2289 2290
P52294 P00352 P05062 Q15843 Q9UF33 Q9BV86 Q12860
2313 2318 2319 2346 2351 2357 2381
Q9BQS8 P06493 Q92616 Q00537 Q7RTS7 Q9BTT0 P07196
2394 2402 2404 2405 2407 2412 2414
Q9BZK3 O94842 P51451 Q14004 P21802 P24941 P22607
2416 2430 2433 2434 2435 2436 2437
Q00535 Q9NWW5 P33947 P02656 P55283 Q14061 P09497
2438 2456 2464 2467 2469 2477 2488
P11908 Q9H492 O15405 Q9H2X9 P47895 Q9NY47 Q8IY18
2490 2491 2495 2500 2502 2511 2521
Q96FJ2 P22612 O43251 P45984 Q9ULD9 Q9UHB6 P0DPK5
2526 2528 2542 2545 2554 2556 2563
Q14324 O75146 P84157 Q96I45 Q9BQJ4 P62942 P05997
2573 2581 2583 2588 2597 2598 2600
P54760 Q9Y608 P61956 Q8N4C8 P98095 P49768 O15131
2611 2616 2617 2618 2620 2630 2637
Q9ULC4 Q3SY84 Q92791 P43694 Q9NYL9 Q9Y5A9 P78385
2653 2654 2655 2657 2673 2680 2688
Q06124 Q15375 P43246 O95297 O14531 P43003 Q5SW79
2689 2690 2709 2715 2716 2723 2733
Q96GZ6 P49589 Q9H4A6 P00533 Q969E2 Q4VC31 Q9P0L2
2735 2736 2740 2742 2745 2752 2753
Q96K19 Q96IZ0 P13995 Q9H0L4 Q8IYT4 P62861 P23497
2754 2755 2756 2757 2758 2759 2763
P10109 Q93045 Q8WXH2 Q5VT25 Q9NSB4 Q14410 Q14393
2772 2798 2799 2801 2802 2803 2805
O94805 Q9NXW2 A0PJW6 Q5D862 P62330 Q96B54 Q9BXT5
2818 2820 2829 2832 2833 2835 2839
Q13242 Q96EL3 Q86V48 O43236 Q9Y5Q5 P27448 Q16082
2844 2847 2853 2854 2860 2862 2870
C9JRZ8 Q86X29 Q9BW11 Q8WXA9 O95400 Q96RE7 P20929
2883 2886 2888 2890 2891 2893 2894
Q9UBL6 Q9NVV5 Q15654 Q27J81 Q8TEA8 P63151 O00592
2901 2903 2909 2913 2914 2916 2917
Q92783 Q9H0W5 P42685 Q9NYB0 O43157 P08686 O00712
2920 2933 2935 2942 2948 2950 2954
Q8NEZ4 O00479 P98173 Q15041 Q4G0F5 Q9BRK5 Q96GF1
2957 2961 2962 2963 2972 2974 2976
O94929 Q9UHY1 P52298 Q9Y570 Q96QD9 P06213 Q5VW38
2979 2980 2982 2983 2984 2986 2988
Q13426 Q15126 Q9UHN6 Q9UI08 Q15819 Q6DKJ4 Q9UKI2
2990 2991 2992 2998 3005 3006 3007
Q93062 Q92979 Q6P4A8 O94855 Q96LJ7 P09668 Q01831
3008 3009 3013 3019 3024 3027 3028
P30622 Q8TED9 Q9Y5V3 P01160 Q9P2P6 O43617 Q7Z417
3029 3032 3036 3041 3045 3050 3057
Q9BRF8 O95873 Q8TBA6 O43583 O43505 Q6NUM9 Q9P2N5
3058 3062 3067 3069 3071 3076 3077
Q9NRW3 Q9Y4I1 Q9UPN4 Q99942 Q9Y4D7 Q8ND30 Q8N122
3080 3081 3085 3090 3092 3097 3102
P78356 O75832 P16298 P19256 P20933 Q6ZUT6 Q9Y2R4
3103 3109 3112 3113 3114 3115 3118
Q9Y3B2 Q14168 Q5ST30 Q6UX04 P13984 Q99595 Q14671
3119 3120 3126 3127 3130 3131 3137
O75882 P06400 P01344 Q9Y487 P83916 Q9ULV0 O00400
3138 3139 3140 3148 3150 3151 3154
Q96ME7 Q13769 Q9UIS9 O95857 O00170 P51668 P22670
3156 3157 3160 3161 3164 3165 3166
Q9BTX1 Q8IZA0 Q9H4L4 Q8IVL5 Q9UMR5 O00194 Q8IVL6
3167 3168 3169 3171 3173 3176 3177
Q8IZX4 Q14678 P48651 O95810 P49840 Q9ULI3 Q96CN9
3178 3179 3184 3187 3190 3191 3192
P27449 O43294 E9PRG8 O15027 P78381 Q7Z2T5 Q9H4I2
3193 3194 3197 3199 3200 3201 3204
Q8TDD1 Q8NF50 P04080 P78383 P52434 Q8TEQ8 Q8IVF7
3207 3208 3213 3214 3215 3216 3217
Q9Y3Q3 O00411 Q6NUK4 Q9UJ70 P49006 Q9P1W8 Q15517
3218 3221 3223 3224 3227 3230 3232
O14523 Q9BPW9 Q8TF09 Q8NI35 P20290 P37198 Q9Y3E0
3233 3235 3239 3240 3241 3242 3249
P57723 Q8NBQ5 Q9NQG5 Q03701 Q0VF96 Q9H1K1 Q86WB0
3251 3254 3257 3260 3261 3264 3265
Q9BWD1 Q8NEW0 Q9UJY4 Q9BPX6 Q9Y287 Q7L5N7 O75223
3269 3270 3271 3272 3275 3279 3281
Q14684 Q9GZT8 P61626 Q68BL7 Q9UIF8 P50748 Q9H7N4
3282 3283 3285 3287 3289 3290 3295
Q99424 Q9BQ70 Q16773 A2RTX5 Q7Z2W4 Q969G5 Q969P0
3297 3301 3302 3304 3310 3311 3315
O75150 Q96HR9 Q9H902 Q96BQ5 P34949 Q13835 Q96J02
3316 3318 3323 3330 3331 3332 3334
Q3KQU3 Q86X55 Q495W5 Q8IUX7 P56645 Q13442 Q9P0P8
3335 3338 3341 3342 3343 3344 3349
Q9UBW8 Q14721 Q9BT92 Q06033 Q9BXR0 Q9H0E3 Q9ULE3
3350 3352 3353 3360 3361 3366 3367
Q5T1M5 Q8IZK6 Q15435 O95183 Q92626 Q8TDW7 Q6P087
3368 3369 3372 3373 3375 3377 3378
Q9H7D7 Q9Y2X8 Q03111 O00233 Q96SB4 A6NDN3 Q9UH99
3380 3381 3384 3392 3393 3395 3399
Q8N4N8 Q6IQ49 P81605 Q01804 Q6UWP8 Q9UPY3 O43896
3400 3401 3402 3404 3411 3413 3414
Q12981 P32856 Q6P1N0 P40938 Q5TA45 P47929 Q15007
3419 3421 3422 3425 3427 3428 3429
Q8TCU6 O75663 Q99614 Q02078 Q9H3S7 Q96SL1 Q69YW2
3435 3437 3438 3439 3445 3447 3448
O60503 P04216 Q6UVJ0 P49454 Q9H1J7 Q9H267 Q5VW36
3449 3450 3454 3455 3456 3460 3461
Q15555 Q7L7X3 O60524 O94955 P31025 Q9BVK2 Q8N9L9
3463 3464 3465 3467 3469 3470 3471
O15379 Q96Q27 P05107 Q4G148 Q6Q6R5 P02458 Q14088
3472 3474 3475 3477 3478 3482 3485
Q8WW12 Q8IWT6 Q13795 Q8IWT3 Q9NXS2 O75953 Q3V6T2
3492 3494 3495 3496 3498 3500 3501
Q6ZMV7 Q9BTT6 Q9NR46 P08575 Q5VU43 Q96SU4 O75909
3504 3506 3508 3511 3512 3514 3516
O60911 P35249 Q96PV0 P04637 Q9UP52 Q96GX5 Q5T655
3519 3522 3523 3525 3526 3528 3529
Q1XH10 Q86UE8 Q92572 Q13884 Q9UKY4 P11172 Q9Y3B9
3531 3532 3533 3535 3538 3539 3540
Q5THJ4 P22003 Q13438 O00178 P51513 P20585 Q9UKZ1
3541 3543 3544 3545 3546 3552 3554
Q6PCB7 Q6NTF9 O43291 B2RTY4 Q9Y6Q5 Q99569 Q9H2K8
3557 3560 3563 3567 3568 3569 3571
Q8N5A5 Q96NB2 O75177 P06132 O60573 Q9HAP6 P18615
3576 3577 3578 3579 3582 3583 3588
Q6ZVX7 Q68DH5 Q8WX92 Q8TEW0 Q92620 Q92995 Q8N3L3
3592 3593 3594 3595 3596 3597 3598
P61769 Q9UKV5 P39210 O43150 Q8WVV4 P05121 Q14643
3599 3601 3602 3604 3605 3606 3607
Q7Z7A1 Q86UR5 Q96CX2 P08123 Q9NSY1 O43633 Q9UIG0
3608 3610 3614 3617 3618 3620 3621
Q8IUD2 P55039 Q8N5S1 O43427 Q6UXI9 Q32P41 O43761
3623 3627 3631 3634 3635 3636 3638
P20930 O14618 O60645 O95502 P61073 Q9UBI6 Q96J42
3639 3640 3641 3646 3647 3650 3651
Q15418 O15021 Q9HCK5 Q8IZ83 Q8TDW0 Q09013 Q6L9W6
3652 3653 3654 3656 3659 3660 3661
Q92485 O95347 P13612 Q13610 Q13573 Q9NYB9 Q15650
3663 3664 3665 3666 3667 3668 3669
Q70HW3 Q99541 Q86UE3 O75127 Q5U3C3 Q9Y3R5 Q9H0N5
3670 3673 3674 3675 3676 3677 3680
Q5T3J3 Q9C004 P05114 Q9BT40 Q9H3U5 Q9H9B1 O00443
3681 3685 3688 3690 3692 3694 3695
Q9Y673 Q14574 P51570 Q9NVH2 P29508 Q13474 Q9BXF6
3698 3701 3702 3703 3704 3705 3710
P38432 Q8IY81 Q92733 Q96A57 A0A1B0GTZ2 Q9NS15 P54284
3711 3712 3714 3716 3717 3720 3721
Q9GZX9 O15231 O60291 Q9Y3X0 Q96P11 Q711Q0 P48751
3724 3725 3726 3728 3730 3734 3737
Q9Y4E1 Q14774 Q9NVU7 O60462 Q149N8 P48029 Q14573
3738 3739 3740 3742 3744 3750 3751
Q8N9H8 Q9UFH2 Q5SZK8 Q9UPP1 Q8NDI1 Q9ULT8 Q6ZSG1
3753 3755 3756 3757 3760 3761 3762
Q9NZU5 Q9UP65 Q9UJX2 Q9Y6U3 Q02224 O75054 Q6IA86
3763 3765 3766 3768 3769 3771 3772
Q9H9E3 Q9NY46 Q9Y5Q8 O75030 O14647 Q9ULF5 Q7Z3T8
3774 3775 3776 3777 3779 3781 3782
Q2M1Z3 Q12756 Q99848 Q15018 O14686 Q3MHD2 Q14676
3784 3785 3786 3787 3788 3789 3791
Q6ZUX3 Q8WXU2 Q15050 Q9H6V9 Q16204 Q5T4T6 Q9P2E5
3792 3796 3798 3800 3802 3803 3804
P78524 Q8NDT2 Q8NHM5 Q9BXT8 Q8N474 P61328 Q8N9M1
3805 3806 3809 3810 3811 3812 3814
Q9Y2E5 Q13895 Q86VH5 P27708 O95613 Q9UJX3 Q9NVE4
3816 3817 3819 3820 3821 3824 3825
Q96S55 Q9H0U9 Q96EV2 P04920 Q9UMR3 B1AK53 P00451
3827 3828 3829 3831 3832 3833 3834
Q9C0H2 Q9BRR3 Q8NB49 Q69YQ0 Q8N1P7 Q8WWQ0 Q8IVT5
3836 3837 3838 3840 3842 3843 3844
Q8N1N0 Q13535 O15357 Q9BQI9 Q7L9B9 Q9BQE4 Q9NXR7
3845 3846 3849 3850 3851 3852 3855
P00711 Q92805 Q8WUF5 Q9Y6V0 Q2VPK5 Q8IWJ2 Q9BRX2
3856 3857 3858 3859 3860 3863 3864
Q96KV7 Q09328 Q96PE2 O75122 P51693 Q8N1B4 Q8IYS0
3865 3866 3867 3868 3869 3870 3871
Q9H1A3 Q9NVR5 Q5QGZ9 Q9ULU4 Q9NXC5 Q13472 A6NEE1
3874 3875 3876 3877 3880 3882 3883
P17081 P49247 Q96NJ5 O95336 Q9BXB4 Q9Y6X5 P01857
3886 3887 3888 3889 3890 3891 3892
P34741 Q9UJF2 Q9H9F9 Q5TH69 Q9UPS8 O00471 H7BZ55
3894 3896 3898 3899 3900 3901 3902
Q16363 Q86YT6 Q8IXH7 O95785 O75970 Q8TAX9 O60583
3905 3906 3907 3908 3909 3910 3911
Q8NCG7 Q6ZU35 Q8IYR2 Q13751 O43683 Q9NSI6 Q8N7H5
3913 3915 3916 3917 3919 3920 3921
Q86VP1 O95476 P53814 O95394 Q96AA8 P02489 Q7Z5L9
3922 3923 3924 3926 3931 3933 3936
Q07890 P10636 P57678 Q7Z4N8 A0A096LP49 Q6ZMP0 Q9NWV8
3938 3941 3943 3946 3947 3948 3949
P49641 Q9BRK4 Q9ULL8 Q9HCI6 Q9H1D0 Q9Y5E7 Q9NZM5
3951 3952 3953 3954 3955 3957 3958
Q5T9S5 P17028 Q9UKG1 Q86WG5 Q9H4B4 Q5M9N0 Q06413
3962 3964 3965 3966 3968 3969 3970
Q96N11 A4FU01 O95248 Q02083 Q96C86 O60262 Q4AC94
3971 3972 3974 3975 3976 3979 3981
O14490 Q9HBJ7 Q12872 P78382 Q9BXP2 Q99447 Q5T4F4
3982 3983 3984 3985 3986 3989 3991
Q68DQ2 P49221 Q9Y6L7 P31944 Q9P270 Q9NQG6 O75365
3992 3995 3996 3997 3998 3999 4000
Q00975 Q86VI3 Q9ULH7 P24863 O43823 Q9Y3E7 Q6NYC8
4002 4003 4004 4005 4006 4007 4008
Q8N2C7 Q9H089 Q96KQ7 Q5SVS4 Q13480 Q8N8E3 P49069
4010 4012 4013 4014 4016 4017 4018
Q9H4L5 P59923 Q07352 Q6P158 Q2TAP0 Q2M3G0 Q8N5R6
4019 4020 4021 4023 4024 4025 4026
Q9BW62 O15083 P37840 Q9Y283 Q8N7X0 Q9UKF2 A6NKL6
4027 4030 4032 4033 4034 4035 4036
Q7Z6M4 Q8N7U6 Q9Y5G6 Q96M83 Q13127 Q9H2U1 Q86UQ4
4038 4039 4041 4042 4044 4046 4047
Q14562 Q6WKZ4 Q92817 P19387 O60879 Q8N556 Q9Y5U4
4049 4050 4051 4056 4057 4058 4059
O95935 Q8N6V9 Q3B7T1 Q13823 Q13601 Q9ULP9 Q9NZN5
4060 4062 4063 4064 4065 4066 4071
Q92913 P55081 Q9P227 Q15223 Q8WYP5 Q3MIS6 P05164
4072 4073 4074 4075 4076 4077 4078
P10911 Q96JN0 Q96JP5 Q6AWC2 Q8WZA9 Q6AI08 Q9H0M0
4079 4080 4081 4082 4083 4084 4085
Q6P280 Q02241 Q8TCU4 Q9UDT6 Q9NR99 Q8TEK3 O95259
4086 4087 4089 4090 4091 4092 4093
Q9Y315 O95486 Q9BZW7 O60343 Q9P2Y5 Q8NAG6 Q9Y6D5
4094 4095 4096 4097 4098 4099 4102
Q14814 Q9BQF6 O94915 P49770 Q96MM6 P02549 O00444
4103 4105 4107 4109 4111 4112 4114
Q6MZZ7 P25208 Q9Y2M5 P51948 O60447 Q8NFQ5 Q9UIR0
4116 4117 4118 4119 4121 4123 4124
Q14807 O94804 Q96PN6 Q8IZW8 Q6N043 Q5RHP9 Q9UJX6
4125 4126 4127 4128 4129 4130 4131
O94964 Q2KHM9 Q8IZ13 Q9BZC7 Q8NGS6 Q5TCY1 Q8TDI7
4132 4133 4134 4135 4136 4137 4139
Q12768 Q52LW3 Q5FWF5 P29475 Q8WVT3 Q9P1Z2 Q9UJX5
4141 4142 4143 4145 4146 4147 4150
Q96PC5 Q5T9G4 P29375 Q15291 Q86UV5 Q3KP66 Q6GQQ9
4153 4155 4156 4158 4160 4161 4162
Q8N998 P09496 P78345 Q9NQW6 A8MTT3 Q5U651 Q9NZB8
4163 4164 4165 4168 4170 4171 4172
Q8WU90 Q9H6S0 Q9ULX7 Q13023 Q9BVJ6 O75052 P35240
4173 4174 4177 4178 4181 4182 4183
Q92466 Q5T1B0 Q9ULJ7 Q13075 P55263 Q2UY09 P78352
4186 4187 4188 4189 4191 4192 4193
Q9P109 Q92989 Q96ES6 Q32NC0 O60469 Q7Z2W7 Q8WXA3
4194 4195 4196 4197 4199 4200 4201
Q8N8H1 Q8TDY2 A6NE01 Q9UPA5 Q658N2 Q9Y2B5 Q6Q759
4202 4205 4206 4209 4210 4214 4215
P50851 Q9ULM3 Q32M84 Q13936 Q2KJY2 Q9Y485 Q9NS91
4216 4217 4218 4219 4220 4221 4224
Q6UXX9 Q3MIN7 O75629 P0C0L4 O14522 Q5TIE3 Q13002
4226 4227 4228 4229 4230 4231 4232
O60308 Q9NRJ4 Q96M86 Q5VV17 Q93074 Q7Z7M9 Q16222
4234 4235 4236 4237 4238 4239 4240
P15735 Q8TAV3 P38935 O60907 Q96DT5 Q4V328 Q9UKA2
4241 4242 4243 4244 4246 4247 4248
Q2LD37 Q9H6R6 Q9BTV5 Q6P9H4 O43497 P0DP91 Q7L0R7
4249 4250 4251 4252 4253 4254 4255
Q7RTW8 Q9H6T0 Q9UKA4 Q53GS7 Q9UBB5 Q8WXX0 Q76I76
4256 4257 4258 4259 4262 4263 4264
P20839 Q13596 Q86XH1 Q8NBJ4 Q58F21 O60494 A1L157
4265 4267 4269 4270 4271 4272 4273
Q13753 O95876 P51808 Q9C0G6 Q86X45 O00154 Q96Q15
4276 4277 4278 4279 4280 4281 4283
P09455 Q7Z407 Q9Y4K1 Q96BR6 Q86UK0 Q9UQ53 Q8IXQ6
4284 4285 4287 4288 4289 4291 4293
Q60I27 A6NI79 Q7Z2Y8 Q9NQ89 Q9Y6J0 Q8NB66 Q5VYJ5
4297 4298 4301 4303 4304 4305 4306
P98171 Q9Y5Y9 Q6ZUT9 Q9BSC4 Q643R3 Q5VVM6 Q9NZL6
4307 4308 4309 4311 4312 4313 4315
O75592 Q8IWV7 Q9H0H0 Q8NET4 Q9H0H5 O15287 Q15025
4317 4319 4320 4321 4322 4324 4327
O95153 A6NCI8 P49675 Q5T5P2 Q6DD87 Q0VDD8 Q5VTR2
4330 4331 4333 4334 4335 4336 4337
Q9UNW1 Q8NDH2 Q8N568 Q9NU22 Q7L1W4 P78536 Q8WW24
4338 4339 4340 4341 4342 4343 4344
Q8N3K9 Q92608 Q9BZE2 Q9UBX1 P18074 Q15256 Q8NEV8
4345 4346 4348 4349 4350 4351 4355
Q96KR6 Q96BP3 Q8N9N2 Q66GS9 Q12950 Q32M78 Q8NBS3
4356 4357 4360 4361 4362 4364 4366
Q5VZ46 A6NMB1 Q5VVJ2 Q8N4C6 Q14D04 Q01167 Q9NS87
4367 4369 4370 4371 4373 4374 4375
Q53F19 Q9GZT6 Q4G0X9 P35916 Q96S44 Q5JSL3 Q8TDL5
4376 4377 4378 4379 4380 4381 4382
Q49A92 Q9Y618 Q8N9B5 Q9P219 Q92673 Q8WY91 Q8IWZ3
4383 4384 4385 4386 4387 4390 4391
Q9Y234 Q9HD67 Q8IZT6 Q08426 Q9NRY6 Q2VPB7 P25054
4394 4395 4397 4398 4400 4401 4402
Q9H8W5 O14745 A7KAX9 Q15257 O94913 Q8IWK6 Q8WXI7
4403 4404 4406 4407 4408 4410 4411
Q9HCK0 Q9BVV6 Q7Z745 Q8NG31 Q9HA64 Q14202 O14569
4412 4413 4415 4417 4418 4419 4420
Q9P218 P0C091 Q13315 O95436 O95714 A2RTY3 Q96QU8
4423 4424 4425 4426 4427 4428 4429
Q96C10 Q9BXX3 Q96JQ0 Q8WX94 Q9C0B2 Q9ULC0 Q6F5E8
4430 4433 4434 4435 4437 4438 4439
Q6PDB4 Q0VAK6 Q9NQT8 P78539 Q8N165 P17948 P25445
4440 4443 4444 4445 4446 4447 4448
Q7Z3V5 P01034 Q15911 Q92547 Q4L180 Q5M775 O75330
4449 4450 4451 4452 4453 4455 4459
P42858 Q14435 B5MCY1 Q4VCS5 Q8TC59 O75071 Q9Y493
4460 4461 4463 4464 4465 4467 4468
Q8NEP9 O60673 P40189 P11215 Q6ZSS3 O15072 Q9UJQ4
4469 4470 4471 4472 4473 4474 4475
P42768 Q7L5A3 Q8N8Z6 Q68DA7 Q6P3R8 P17021 Q8WY64
4476 4477 4478 4479 4480 4481 4482
Q6PCB5 A1L443 Q96M91 Q76G19 Q9H5I5 P51843 Q9NXL9
4483 4485 4486 4487 4489 4491 4493
Q13395 Q08188 Q5BJE1 Q9NRE2
4496 4498 4500 4501 rows_with_na <- as.numeric(rows_with_na)
rows_with_na [1] 12 39 41 49 124 129 135 197 200 215 224 232 296 320
[15] 353 396 484 497 506 541 565 570 707 718 733 846 881 912
[29] 967 1018 1053 1126 1182 1204 1254 1290 1328 1357 1382 1428 1437 1444
[43] 1451 1486 1498 1532 1534 1564 1565 1630 1633 1648 1654 1747 1762 1768
[57] 1827 1847 1892 1916 1925 1938 1972 2000 2007 2025 2035 2036 2038 2098
[71] 2100 2111 2118 2147 2150 2156 2165 2167 2169 2201 2206 2218 2221 2227
[85] 2235 2239 2244 2247 2271 2289 2290 2313 2318 2319 2346 2351 2357 2381
[99] 2394 2402 2404 2405 2407 2412 2414 2416 2430 2433 2434 2435 2436 2437
[113] 2438 2456 2464 2467 2469 2477 2488 2490 2491 2495 2500 2502 2511 2521
[127] 2526 2528 2542 2545 2554 2556 2563 2573 2581 2583 2588 2597 2598 2600
[141] 2611 2616 2617 2618 2620 2630 2637 2653 2654 2655 2657 2673 2680 2688
[155] 2689 2690 2709 2715 2716 2723 2733 2735 2736 2740 2742 2745 2752 2753
[169] 2754 2755 2756 2757 2758 2759 2763 2772 2798 2799 2801 2802 2803 2805
[183] 2818 2820 2829 2832 2833 2835 2839 2844 2847 2853 2854 2860 2862 2870
[197] 2883 2886 2888 2890 2891 2893 2894 2901 2903 2909 2913 2914 2916 2917
[211] 2920 2933 2935 2942 2948 2950 2954 2957 2961 2962 2963 2972 2974 2976
[225] 2979 2980 2982 2983 2984 2986 2988 2990 2991 2992 2998 3005 3006 3007
[239] 3008 3009 3013 3019 3024 3027 3028 3029 3032 3036 3041 3045 3050 3057
[253] 3058 3062 3067 3069 3071 3076 3077 3080 3081 3085 3090 3092 3097 3102
[267] 3103 3109 3112 3113 3114 3115 3118 3119 3120 3126 3127 3130 3131 3137
[281] 3138 3139 3140 3148 3150 3151 3154 3156 3157 3160 3161 3164 3165 3166
[295] 3167 3168 3169 3171 3173 3176 3177 3178 3179 3184 3187 3190 3191 3192
[309] 3193 3194 3197 3199 3200 3201 3204 3207 3208 3213 3214 3215 3216 3217
[323] 3218 3221 3223 3224 3227 3230 3232 3233 3235 3239 3240 3241 3242 3249
[337] 3251 3254 3257 3260 3261 3264 3265 3269 3270 3271 3272 3275 3279 3281
[351] 3282 3283 3285 3287 3289 3290 3295 3297 3301 3302 3304 3310 3311 3315
[365] 3316 3318 3323 3330 3331 3332 3334 3335 3338 3341 3342 3343 3344 3349
[379] 3350 3352 3353 3360 3361 3366 3367 3368 3369 3372 3373 3375 3377 3378
[393] 3380 3381 3384 3392 3393 3395 3399 3400 3401 3402 3404 3411 3413 3414
[407] 3419 3421 3422 3425 3427 3428 3429 3435 3437 3438 3439 3445 3447 3448
[421] 3449 3450 3454 3455 3456 3460 3461 3463 3464 3465 3467 3469 3470 3471
[435] 3472 3474 3475 3477 3478 3482 3485 3492 3494 3495 3496 3498 3500 3501
[449] 3504 3506 3508 3511 3512 3514 3516 3519 3522 3523 3525 3526 3528 3529
[463] 3531 3532 3533 3535 3538 3539 3540 3541 3543 3544 3545 3546 3552 3554
[477] 3557 3560 3563 3567 3568 3569 3571 3576 3577 3578 3579 3582 3583 3588
[491] 3592 3593 3594 3595 3596 3597 3598 3599 3601 3602 3604 3605 3606 3607
[505] 3608 3610 3614 3617 3618 3620 3621 3623 3627 3631 3634 3635 3636 3638
[519] 3639 3640 3641 3646 3647 3650 3651 3652 3653 3654 3656 3659 3660 3661
[533] 3663 3664 3665 3666 3667 3668 3669 3670 3673 3674 3675 3676 3677 3680
[547] 3681 3685 3688 3690 3692 3694 3695 3698 3701 3702 3703 3704 3705 3710
[561] 3711 3712 3714 3716 3717 3720 3721 3724 3725 3726 3728 3730 3734 3737
[575] 3738 3739 3740 3742 3744 3750 3751 3753 3755 3756 3757 3760 3761 3762
[589] 3763 3765 3766 3768 3769 3771 3772 3774 3775 3776 3777 3779 3781 3782
[603] 3784 3785 3786 3787 3788 3789 3791 3792 3796 3798 3800 3802 3803 3804
[617] 3805 3806 3809 3810 3811 3812 3814 3816 3817 3819 3820 3821 3824 3825
[631] 3827 3828 3829 3831 3832 3833 3834 3836 3837 3838 3840 3842 3843 3844
[645] 3845 3846 3849 3850 3851 3852 3855 3856 3857 3858 3859 3860 3863 3864
[659] 3865 3866 3867 3868 3869 3870 3871 3874 3875 3876 3877 3880 3882 3883
[673] 3886 3887 3888 3889 3890 3891 3892 3894 3896 3898 3899 3900 3901 3902
[687] 3905 3906 3907 3908 3909 3910 3911 3913 3915 3916 3917 3919 3920 3921
[701] 3922 3923 3924 3926 3931 3933 3936 3938 3941 3943 3946 3947 3948 3949
[715] 3951 3952 3953 3954 3955 3957 3958 3962 3964 3965 3966 3968 3969 3970
[729] 3971 3972 3974 3975 3976 3979 3981 3982 3983 3984 3985 3986 3989 3991
[743] 3992 3995 3996 3997 3998 3999 4000 4002 4003 4004 4005 4006 4007 4008
[757] 4010 4012 4013 4014 4016 4017 4018 4019 4020 4021 4023 4024 4025 4026
[771] 4027 4030 4032 4033 4034 4035 4036 4038 4039 4041 4042 4044 4046 4047
[785] 4049 4050 4051 4056 4057 4058 4059 4060 4062 4063 4064 4065 4066 4071
[799] 4072 4073 4074 4075 4076 4077 4078 4079 4080 4081 4082 4083 4084 4085
[813] 4086 4087 4089 4090 4091 4092 4093 4094 4095 4096 4097 4098 4099 4102
[827] 4103 4105 4107 4109 4111 4112 4114 4116 4117 4118 4119 4121 4123 4124
[841] 4125 4126 4127 4128 4129 4130 4131 4132 4133 4134 4135 4136 4137 4139
[855] 4141 4142 4143 4145 4146 4147 4150 4153 4155 4156 4158 4160 4161 4162
[869] 4163 4164 4165 4168 4170 4171 4172 4173 4174 4177 4178 4181 4182 4183
[883] 4186 4187 4188 4189 4191 4192 4193 4194 4195 4196 4197 4199 4200 4201
[897] 4202 4205 4206 4209 4210 4214 4215 4216 4217 4218 4219 4220 4221 4224
[911] 4226 4227 4228 4229 4230 4231 4232 4234 4235 4236 4237 4238 4239 4240
[925] 4241 4242 4243 4244 4246 4247 4248 4249 4250 4251 4252 4253 4254 4255
[939] 4256 4257 4258 4259 4262 4263 4264 4265 4267 4269 4270 4271 4272 4273
[953] 4276 4277 4278 4279 4280 4281 4283 4284 4285 4287 4288 4289 4291 4293
[967] 4297 4298 4301 4303 4304 4305 4306 4307 4308 4309 4311 4312 4313 4315
[981] 4317 4319 4320 4321 4322 4324 4327 4330 4331 4333 4334 4335 4336 4337
[995] 4338 4339 4340 4341 4342 4343 4344 4345 4346 4348 4349 4350 4351 4355
[1009] 4356 4357 4360 4361 4362 4364 4366 4367 4369 4370 4371 4373 4374 4375
[1023] 4376 4377 4378 4379 4380 4381 4382 4383 4384 4385 4386 4387 4390 4391
[1037] 4394 4395 4397 4398 4400 4401 4402 4403 4404 4406 4407 4408 4410 4411
[1051] 4412 4413 4415 4417 4418 4419 4420 4423 4424 4425 4426 4427 4428 4429
[1065] 4430 4433 4434 4435 4437 4438 4439 4440 4443 4444 4445 4446 4447 4448
[1079] 4449 4450 4451 4452 4453 4455 4459 4460 4461 4463 4464 4465 4467 4468
[1093] 4469 4470 4471 4472 4473 4474 4475 4476 4477 4478 4479 4480 4481 4482
[1107] 4483 4485 4486 4487 4489 4491 4493 4496 4498 4500 4501# 2. Remove rows with NA values
Protein_DF_Abundance <- Protein_DF_Abundance[-rows_with_na, ]
# 3. Sanity check
Protein_DF_Abundance %>% dim()[1] 3384 10TMM Normalization
library(edgeR)
# Create a DGEList from your count data
y <- DGEList(counts = Protein_DF_Abundance)
y$samples group lib.size norm.factors
S1 1 351848467600 1
S3 1 353179750800 1
S5 1 344605055500 1
S7 1 353442458300 1
S9 1 348344717400 1
S2 1 364195220100 1
S4 1 340212826000 1
S6 1 376791648000 1
S8 1 365563625400 1
S10 1 328940277650 1# Assign group to DGEList object
y$samples$group <- Meta$Cond
# Calculate normalization factors using TMM method
y <- calcNormFactors(y, method = "TMM")
# Now the object 'y' has the normalization factors calculated
# If you want to proceed with RUVSeq, you need to use these normalization factors
# when creating the counts matrix that will be input to RUVSeq
norm_counts <- t( t(y$counts) / y$samples$norm.factors )
log2_norm_counts <- log2(norm_counts)Prepare Data Object for RUVs
counts need to be integer values and in a numeric matrix
counts <- as.matrix(log2_norm_counts)
# Create a DataFrame for the phenoData
phenoData <- DataFrame(Meta)
# Now create the RangedSummarizedExperiment necessary for RUVs input
set <- SummarizedExperiment(assays = counts, metadata =phenoData)REQUIRED RUVs Matrix
# Generate a background matrix where each set of replicates are in a row
# and null spaces where there are replicate mismatches get the value -1.
# This will be used in the RUVs function, which is the typeII method to
# remove unwanted variation in the RUVs package. This will be used for all
# RUVs permutations where the number of variation factors will be changed.
scIdx <- matrix(-1, nrow = 6, ncol = 3)
scIdx[1, 1:3] <- c(which(colnames(counts) %in% c("S6", "S8", "S10")))
scIdx[2, 1:3] <- c(which(colnames(counts) %in% c("S5", "S7", "S9")))
scIdx[3, 1] <- c(which(colnames(counts) %in% c("S2")))
scIdx[4, 1] <- c(which(colnames(counts) %in% c("S1")))
scIdx[5, 1] <- c(which(colnames(counts) %in% c("S4")))
scIdx[6, 1] <- c(which(colnames(counts) %in% c("S3")))
scIdx [,1] [,2] [,3]
[1,] 8 9 10
[2,] 3 4 5
[3,] 6 -1 -1
[4,] 1 -1 -1
[5,] 7 -1 -1
[6,] 2 -1 -1Dupcor + RUVs K = 1
Apply RUVs function from RUVSeq
set <- RUVSeq::RUVs(x = counts, k =1, scIdx = scIdx, isLog = TRUE)
RUV_1 <- set$W[,1]
set$W W_1
S1 -7.933894
S3 -8.164925
S5 -8.286632
S7 -7.576930
S9 -8.574838
S2 -7.952186
S4 -8.117729
S6 -8.495872
S8 -8.337804
S10 -7.586187phenoData$RUV_1 <- RUV_1
# apply duplicateCorrelation is two rounds
design <- model.matrix(~ Cond + RUV_1, phenoData)
vobj_tmp = voom(counts, design, plot = TRUE)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
dupcor <- duplicateCorrelation(counts , design, block = Meta$Ind)
# run voom considering the duplicateCorrelation results
# in order to compute more accurate precision weights
# Otherwise, use the results from the first voom run
vobj = voom( counts = counts, design = design, plot=TRUE, block=Meta$Ind, correlation=dupcor$consensus)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Estimate linear mixed model with a single variance component
# Fit the model for each gene,
dupcor <- duplicateCorrelation(vobj, design, block=Meta$Ind)
# But this step uses only the genome-wide average for the random effect
fitDupCor <- lmFit(counts, design, block=Meta$Ind, correlation=dupcor$consensus)
# Fit Empirical Bayes for moderated t-statistics
fitDupCor_2 <- eBayes( fitDupCor )
# Summarize
results_Dupcor <- decideTests(fitDupCor_2)
summary(results_Dupcor) (Intercept) CondDox RUV_1
Down 1 182 0
NotSig 50 3161 3383
Up 3333 41 1# Toptable summary for more comprehensive results
toptable_Dupcor <- topTable(fitDupCor_2, coef = "CondDox", number = nrow(Protein_DF_Abundance), p.value = 1)
toptable_Dupcor$Protein <- rownames(toptable_Dupcor)
toptable_Dupcor logFC AveExpr t P.Value adj.P.Val
Q15327 -3.5538167761 23.99047 -16.743392583 2.054348e-08 6.951913e-05
O76021 -2.1410928975 24.25375 -13.552273075 1.444049e-07 2.443330e-04
Q96LW7 -1.6342957224 19.97143 -12.658156240 2.690260e-07 3.034614e-04
Q969Q1 -4.3423803749 20.84232 -11.920968346 4.632261e-07 3.918893e-04
P19388 -1.1658966201 20.44496 -11.622278836 5.822611e-07 3.940743e-04
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P02545 0.0158073427 30.55125 0.147851779 8.855253e-01 9.435194e-01
P61421 -0.0242455672 24.46109 -0.146216897 8.867811e-01 9.439150e-01
P20340 0.0176739001 25.74600 0.145859084 8.870560e-01 9.439150e-01
Q9BQA9 0.0170455743 21.80190 0.145606415 8.872502e-01 9.439150e-01
P25789 -0.0140235078 25.34319 -0.145580831 8.872698e-01 9.439150e-01
Q9BXW7 -0.0197262338 25.09723 -0.145552979 8.872912e-01 9.439150e-01
Q9UKE5 0.0164577249 21.37314 0.144672926 8.879675e-01 9.440395e-01
O94973 -0.0197305999 24.55550 -0.144541369 8.880685e-01 9.440395e-01
Q96MW7 -0.0346474874 20.25145 -0.144057900 8.884401e-01 9.440395e-01
P57105 0.0161700546 25.13814 0.143948518 8.885242e-01 9.440395e-01
P61009 -0.0137165968 24.59434 -0.143144496 8.891421e-01 9.443995e-01
Q9H2H9 -0.0305677796 22.50471 -0.141746433 8.902168e-01 9.452443e-01
Q9H6E4 0.0525545575 21.31375 0.141102350 8.907120e-01 9.454735e-01
Q8N9W4 0.1030273788 19.69434 0.140490112 8.911828e-01 9.455285e-01
Q8NE71 -0.0329983701 22.86666 -0.140308236 8.913226e-01 9.455285e-01
Q9NZN4 -0.0441618003 21.49412 -0.138793607 8.924875e-01 9.464674e-01
Q8TEM1 0.0200278664 25.36212 0.138303219 8.928647e-01 9.465708e-01
O43819 -0.0195882447 22.18280 -0.137325194 8.936170e-01 9.467461e-01
Q12846 -0.0173400663 23.47353 -0.137187013 8.937233e-01 9.467461e-01
P07355 0.0282842760 30.50622 0.136667009 8.941234e-01 9.467461e-01
Q6P0N0 0.0204778709 21.38154 0.136633590 8.941491e-01 9.467461e-01
Q6P1M3 0.0223517389 22.36122 0.136184062 8.944950e-01 9.468161e-01
Q13177 0.0251638166 21.80719 0.133053810 8.969042e-01 9.490693e-01
Q9Y4G6 0.0148237056 26.32653 0.132289782 8.974923e-01 9.493948e-01
Q5SV97 0.0374634803 20.72334 0.130381893 8.989614e-01 9.506517e-01
O75907 0.0342642041 21.05161 0.130002991 8.992532e-01 9.506632e-01
P47897 -0.0160481348 26.18752 -0.129410403 8.997096e-01 9.508487e-01
P63000 0.0191741341 26.66655 0.128944083 9.000688e-01 9.509313e-01
Q96G01 0.0344546541 20.55211 0.128538371 9.003813e-01 9.509619e-01
Q9NTK5 0.0268868800 22.37886 0.128112615 9.007093e-01 9.509619e-01
Q86UP2 -0.0140971525 28.39753 -0.127812007 9.009409e-01 9.509619e-01
O95479 -0.0149775013 22.51775 -0.127211174 9.014038e-01 9.511539e-01
P30084 0.0136627494 27.63577 0.125249032 9.029157e-01 9.524523e-01
Q9NRV9 0.0285287161 23.42682 0.124152688 9.037607e-01 9.530465e-01
P62805 0.0194275477 24.52758 0.123089166 9.045805e-01 9.532769e-01
P10301 0.0196646958 25.56298 0.122908464 9.047198e-01 9.532769e-01
O43684 -0.0140960751 24.99095 -0.122772994 9.048243e-01 9.532769e-01
Q14155 -0.0700116742 20.39321 -0.121205267 9.060330e-01 9.542532e-01
Q8TD19 0.0582896964 20.56313 0.116825036 9.094115e-01 9.573678e-01
P69905 0.0270981081 24.97097 0.116522213 9.096452e-01 9.573678e-01
O14958 -0.0365787285 26.10980 -0.116020812 9.100321e-01 9.573678e-01
Q15560 -0.0373465566 19.70265 -0.115712930 9.102696e-01 9.573678e-01
Q9Y6N5 -0.0502072562 22.24438 -0.115537810 9.104048e-01 9.573678e-01
O76003 0.0217527662 21.56450 0.114792868 9.109796e-01 9.576748e-01
Q9BR39 -0.0100676478 26.05558 -0.114171347 9.114593e-01 9.578815e-01
Q5TAQ9 0.0318414456 21.69117 0.112986831 9.123736e-01 9.585062e-01
Q96E39 0.0312585100 22.34399 0.112667203 9.126203e-01 9.585062e-01
P61204 -0.0112127960 25.30750 -0.111936643 9.131843e-01 9.588010e-01
Q14934 -0.0184688461 20.21072 -0.111313190 9.136656e-01 9.590088e-01
Q15005 0.0124065929 25.21650 0.110476328 9.143118e-01 9.592422e-01
Q9C0D9 0.0296622413 21.40688 0.110291001 9.144549e-01 9.592422e-01
Q9Y320 0.0119171151 25.47633 0.108797575 9.156081e-01 9.601543e-01
P11498 0.0339686151 21.99105 0.107547250 9.165738e-01 9.603356e-01
O60763 -0.0139831853 24.73159 -0.107441446 9.166556e-01 9.603356e-01
P33993 0.0296264221 22.95476 0.106818749 9.171366e-01 9.603356e-01
Q86VU5 -0.0246204336 23.37687 -0.106469690 9.174062e-01 9.603356e-01
P35998 -0.0100998261 25.38112 -0.106467932 9.174076e-01 9.603356e-01
O75369 -0.0491792455 25.49266 -0.106366787 9.174857e-01 9.603356e-01
Q9P2R3 -0.0160556032 23.35655 -0.106001999 9.177675e-01 9.603356e-01
P20618 0.0094208407 24.82056 0.105592157 9.180842e-01 9.603700e-01
Q5XKP0 0.0182047101 25.41729 0.104271843 9.191043e-01 9.611400e-01
P51809 0.0184585233 23.30146 0.102756756 9.202752e-01 9.620671e-01
O15228 -0.0163471219 23.14290 -0.102081817 9.207968e-01 9.623151e-01
P46939 0.0183565192 25.16419 0.101187000 9.214885e-01 9.627406e-01
P04062 -0.0186540967 23.81559 -0.099522119 9.227755e-01 9.633472e-01
P09382 -0.0307928569 25.49314 -0.098894180 9.232610e-01 9.633472e-01
P27694 0.0277877963 24.86406 0.098887044 9.232665e-01 9.633472e-01
O00462 -0.0097998990 25.08341 -0.098735102 9.233840e-01 9.633472e-01
P22307 -0.0145158437 25.76061 -0.098594857 9.234924e-01 9.633472e-01
Q9NZM3 0.0221290468 23.74942 0.097336464 9.244655e-01 9.636073e-01
P34931 -0.0198052635 24.65605 -0.097163206 9.245995e-01 9.636073e-01
P16219 -0.0142894513 24.99126 -0.096877470 9.248205e-01 9.636073e-01
P00734 -0.0218670313 20.79997 -0.096188763 9.253531e-01 9.636073e-01
Q9BS26 0.0118885102 26.53071 0.095918890 9.255618e-01 9.636073e-01
Q14974 0.0091638057 26.60580 0.095642815 9.257753e-01 9.636073e-01
Q9UN42 0.0529851700 24.44938 0.095168421 9.261423e-01 9.636073e-01
P50402 -0.0092716097 25.43118 -0.094973649 9.262929e-01 9.636073e-01
P01112 0.0135000733 24.14441 0.094958654 9.263045e-01 9.636073e-01
Q9NUM4 0.0223334393 22.01896 0.094471818 9.266811e-01 9.636750e-01
Q9BWM7 0.0217927237 24.70386 0.094096025 9.269718e-01 9.636750e-01
Q969M1 0.0210633620 21.82823 0.093770125 9.272239e-01 9.636750e-01
P05166 0.0107373080 25.22551 0.093072210 9.277638e-01 9.639401e-01
Q8N2H3 0.0407270612 23.71033 0.092320385 9.283455e-01 9.642394e-01
P46060 0.0101036945 22.55457 0.091927779 9.286493e-01 9.642394e-01
P24043 -0.0286933388 22.52164 -0.091018854 9.293526e-01 9.642394e-01
P13051 -0.0239032109 20.23308 -0.090774256 9.295419e-01 9.642394e-01
Q02252 0.0114156845 26.84969 0.090686632 9.296097e-01 9.642394e-01
Q8NFH5 -0.0086793530 20.80922 -0.089857588 9.302513e-01 9.642394e-01
Q9UBM7 0.0265568097 24.51966 0.089756303 9.303297e-01 9.642394e-01
Q9NVT9 -0.0695866795 24.16418 -0.089440953 9.305737e-01 9.642394e-01
Q15691 -0.0244255009 23.41869 -0.089385757 9.306164e-01 9.642394e-01
Q15070 -0.0250575927 24.80790 -0.087453602 9.321120e-01 9.654389e-01
P06865 0.0111440839 24.87987 0.087153035 9.323446e-01 9.654389e-01
Q4G176 -0.0116557149 24.14503 -0.084429697 9.344531e-01 9.667488e-01
P00761 0.0096551066 31.08365 0.083661976 9.350476e-01 9.667488e-01
O00425 -0.0088968604 26.12775 -0.082792556 9.357208e-01 9.667488e-01
Q02127 0.0119945538 22.14724 0.082729316 9.357698e-01 9.667488e-01
P08F94 -0.0186971056 21.20035 -0.082536801 9.359189e-01 9.667488e-01
Q14677 0.0118688959 20.45310 0.082354795 9.360599e-01 9.667488e-01
P08651 -0.0121724593 20.69112 -0.082077547 9.362746e-01 9.667488e-01
P28066 0.0076420581 24.33706 0.081882140 9.364259e-01 9.667488e-01
Q14249 0.0095893912 24.57991 0.081682259 9.365807e-01 9.667488e-01
Q9UDY2 -0.0253243845 20.15616 -0.081630790 9.366206e-01 9.667488e-01
Q99755 0.0418349618 18.76583 0.081460879 9.367522e-01 9.667488e-01
Q9Y2P4 0.0127607804 24.04330 0.080398436 9.375751e-01 9.673031e-01
P63165 0.0123175233 21.71677 0.079020619 9.386425e-01 9.678086e-01
Q9NYK1 -0.0498251988 23.31318 -0.078869131 9.387598e-01 9.678086e-01
Q9H019 -0.0092611101 22.90488 -0.078658462 9.389230e-01 9.678086e-01
Q8TDY8 -0.0426163562 19.12771 -0.078157765 9.393109e-01 9.679082e-01
Q9NYF8 0.0085150296 25.65458 0.077439550 9.398674e-01 9.679082e-01
Q9HD23 0.0119060604 21.38225 0.077426125 9.398778e-01 9.679082e-01
P48723 -0.0102901119 22.73254 -0.076842096 9.403303e-01 9.680796e-01
Q99594 -0.0193135842 20.32437 -0.076120062 9.408898e-01 9.682065e-01
Q9Y2U8 0.0098060997 22.99646 0.075944555 9.410258e-01 9.682065e-01
O75027 -0.0099842542 24.53979 -0.074018291 9.425185e-01 9.691118e-01
Q5SSJ5 0.0073752285 26.66669 0.073747130 9.427287e-01 9.691118e-01
O75400 -0.0124379818 24.09084 -0.073426358 9.429773e-01 9.691118e-01
P31327 0.0136571174 23.68287 0.073226019 9.431326e-01 9.691118e-01
Q9Y2A7 0.0125353448 23.81438 0.072736143 9.435123e-01 9.691118e-01
Q9UID3 0.0295843740 19.75980 0.072304102 9.438472e-01 9.691118e-01
P14543 -0.0167919221 23.69376 -0.071929886 9.441372e-01 9.691118e-01
P17152 -0.0105953273 23.41777 -0.071853200 9.441967e-01 9.691118e-01
Q13620 0.0145089750 23.68199 0.068848276 9.465262e-01 9.710227e-01
P29992 -0.0064416056 25.11985 -0.068711426 9.466323e-01 9.710227e-01
Q5T2T1 0.0097889222 19.07726 0.067750831 9.473772e-01 9.714922e-01
P62140 0.0079203715 26.50835 0.066117357 9.486438e-01 9.721262e-01
Q969V3 -0.0091642882 24.65837 -0.065961302 9.487649e-01 9.721262e-01
O75063 -0.0196776515 20.88879 -0.065731441 9.489431e-01 9.721262e-01
O43765 -0.0198025217 25.84904 -0.065471807 9.491445e-01 9.721262e-01
Q8N2F6 -0.0198511112 22.52100 -0.063289545 9.508370e-01 9.735650e-01
Q8WVX9 0.0060289228 18.79905 0.059937211 9.534375e-01 9.759324e-01
Q14139 -0.0057615311 22.36123 -0.057894924 9.550221e-01 9.772588e-01
P82933 0.0054829992 25.65392 0.056171698 9.563593e-01 9.781625e-01
Q01813 0.0167370873 27.35581 0.056011786 9.564834e-01 9.781625e-01
Q9BX66 0.0143358680 21.78936 0.055212659 9.571035e-01 9.783663e-01
P60891 0.0067843410 25.93807 0.054762504 9.574529e-01 9.783663e-01
P11021 0.0063562359 30.65990 0.054438581 9.577043e-01 9.783663e-01
Q9NSV4 0.0171790228 18.90526 0.054264910 9.578391e-01 9.783663e-01
P02786 0.0070610326 28.18432 0.053292307 9.585939e-01 9.788418e-01
Q15075 0.0050036274 26.59854 0.052648238 9.590938e-01 9.790569e-01
P50440 0.0143064229 23.95149 0.052212300 9.594322e-01 9.791069e-01
Q96ER9 -0.0102512056 22.44630 -0.051768147 9.597770e-01 9.791635e-01
Q9H0V9 -0.0093153054 23.67906 -0.051198399 9.602192e-01 9.793194e-01
Q96SJ8 -0.0156754084 21.16539 -0.049857987 9.612597e-01 9.800853e-01
Q9UDR5 0.0064776062 26.72489 0.047750841 9.628956e-01 9.812624e-01
Q99436 0.0067940073 24.84376 0.046876834 9.635742e-01 9.812624e-01
P07910 0.0061472861 25.80692 0.046681226 9.637261e-01 9.812624e-01
P43121 0.0072381493 25.74715 0.046638044 9.637596e-01 9.812624e-01
Q969Z3 -0.0054001601 25.20349 -0.046171842 9.641216e-01 9.812624e-01
Q9P291 0.0057158178 25.18091 0.046130028 9.641541e-01 9.812624e-01
Q96I51 -0.0099153320 22.36944 -0.045618276 9.645514e-01 9.813716e-01
P12270 -0.0063074599 25.52478 -0.045036686 9.650030e-01 9.814281e-01
P62993 -0.0191703184 21.93934 -0.044465395 9.654466e-01 9.814281e-01
O43852 -0.0066212747 26.73698 -0.044426234 9.654770e-01 9.814281e-01
O00186 -0.0047971737 24.18030 -0.041618048 9.676578e-01 9.833495e-01
P61020 0.0097273667 23.77504 0.041026201 9.681174e-01 9.835213e-01
Q9UJW0 -0.0059093156 21.61949 -0.039172094 9.695575e-01 9.846886e-01
P50213 -0.0051954398 29.24408 -0.038559279 9.700335e-01 9.848765e-01
P13861 -0.0050914180 25.47757 -0.037951567 9.705055e-01 9.850378e-01
Q8NDZ4 -0.0086632938 22.12834 -0.037303220 9.710091e-01 9.850378e-01
P35659 -0.0044616574 24.57097 -0.037053420 9.712032e-01 9.850378e-01
P56747 0.0187623726 22.70278 0.036814390 9.713888e-01 9.850378e-01
O95861 -0.0054869445 21.62864 -0.036481025 9.716478e-01 9.850378e-01
Q68D91 -0.0095284586 21.60360 -0.034982953 9.728115e-01 9.858407e-01
Q96D53 -0.0072857034 21.18247 -0.034343139 9.733086e-01 9.858407e-01
Q9GZP0 0.0175080541 19.10221 0.034336389 9.733138e-01 9.858407e-01
Q9UBX3 -0.0059197351 24.59611 -0.033774291 9.737505e-01 9.859879e-01
Q6Y288 0.0073062541 19.45079 0.033286033 9.741298e-01 9.860329e-01
Q58EX2 0.0102423104 20.21960 0.032597398 9.746648e-01 9.860329e-01
Q9P035 -0.0044522294 24.84269 -0.032591930 9.746690e-01 9.860329e-01
Q92614 -0.0028647118 27.76244 -0.032011880 9.751197e-01 9.861940e-01
O75376 0.0074416599 21.25635 0.031302942 9.756705e-01 9.864562e-01
O43615 0.0037622817 26.76185 0.030250962 9.764878e-01 9.867703e-01
O43169 0.0032027964 25.40996 0.030152532 9.765643e-01 9.867703e-01
Q6UW68 0.0046572920 24.02324 0.028940720 9.775059e-01 9.871844e-01
P35968 0.0047097694 22.81438 0.028874123 9.775576e-01 9.871844e-01
Q9GZY4 -0.0055021156 22.45684 -0.028419001 9.779113e-01 9.872469e-01
Q8IZQ5 0.0066248105 21.22786 0.027632841 9.785221e-01 9.874605e-01
O60841 -0.0035220559 23.29606 -0.027395651 9.787065e-01 9.874605e-01
P28288 -0.0036256509 25.16783 -0.026983209 9.790269e-01 9.874895e-01
O75417 0.0054159815 22.72883 0.024822018 9.807064e-01 9.888887e-01
Q15067 0.0044210791 24.49190 0.023960695 9.813757e-01 9.892688e-01
P26368 -0.0022281622 25.59537 -0.022554523 9.824685e-01 9.897040e-01
P23919 -0.0032968988 23.83964 -0.022524558 9.824918e-01 9.897040e-01
Q155Q3 0.0028108220 19.49408 0.021983738 9.829121e-01 9.897040e-01
Q13232 -0.0035464856 23.30546 -0.021899863 9.829773e-01 9.897040e-01
Q6FI81 0.0039575492 22.46627 0.021490816 9.832952e-01 9.897296e-01
O00505 0.0085658006 21.80293 0.019373553 9.849407e-01 9.910911e-01
Q15008 0.0024531736 24.84515 0.018699420 9.854646e-01 9.913235e-01
O00743 -0.0030229107 20.62747 -0.018142189 9.858977e-01 9.914644e-01
Q32P44 -0.0035448747 20.06958 -0.015770667 9.877410e-01 9.930230e-01
P78417 0.0018041193 23.56780 0.015101749 9.882609e-01 9.932506e-01
P14621 -0.0045005530 20.78173 -0.014573761 9.886713e-01 9.933680e-01
Q9BYD1 0.0015316464 24.46061 0.014116314 9.890268e-01 9.934303e-01
P61586 0.0013072005 26.74816 0.013411483 9.895747e-01 9.936857e-01
Q14566 0.0021581420 23.68538 0.012937085 9.899434e-01 9.937611e-01
P10915 0.0050398203 23.61243 0.012197305 9.905185e-01 9.940434e-01
Q9BXS5 -0.0015175385 22.77994 -0.009945018 9.922692e-01 9.955052e-01
Q6P1M0 -0.0013230822 22.76586 -0.009290689 9.927778e-01 9.955410e-01
Q9C0D5 0.0037181052 19.95329 0.009142181 9.928933e-01 9.955410e-01
Q15185 0.0008048923 24.10663 0.008508503 9.933859e-01 9.955435e-01
P51153 0.0012681861 22.33613 0.008381986 9.934842e-01 9.955435e-01
P29144 0.0012070742 25.09501 0.007639958 9.940610e-01 9.958267e-01
P09543 0.0006074187 25.46963 0.004251034 9.966954e-01 9.981702e-01
Q9BZF1 -0.0006529423 22.69373 -0.002977151 9.976857e-01 9.988664e-01
Q92538 0.0002573516 22.84061 0.002240344 9.982584e-01 9.991413e-01
Q96N64 -0.0002124377 21.72457 -0.001860990 9.985533e-01 9.991413e-01
Q52LJ0 -0.0003543919 23.01653 -0.001309060 9.989824e-01 9.991413e-01
P54753 -0.0002160733 24.88610 -0.001104627 9.991413e-01 9.991413e-01
B Protein
Q15327 9.41678906 Q15327
O76021 7.85938218 O76021
Q96LW7 7.32858329 Q96LW7
Q969Q1 6.85315287 Q969Q1
P19388 6.64995911 P19388
Q96GQ7 6.08177746 Q96GQ7
O43159 5.68418526 O43159
Q6EMK4 5.13889238 Q6EMK4
P17844 4.83188794 P17844
Q96PU8 4.51212370 Q96PU8
Q14498 4.45613928 Q14498
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Q9UHD9 -6.66251916 Q9UHD9
Q16630 -6.66256767 Q16630
Q15172 -6.66291309 Q15172
Q13418 -6.66299551 Q13418
Q02641 -6.66360761 Q02641
Q86WA6 -6.66389144 Q86WA6
Q12769 -6.66403175 Q12769
Q14011 -6.66457320 Q14011
P08579 -6.66469707 P08579
Q9Y6A9 -6.66472634 Q9Y6A9
P32189 -6.66473332 P32189
Q9BU61 -6.66475696 Q9BU61
Q8NI37 -6.66502503 Q8NI37
O43707 -6.66512341 O43707
Q9BYX7 -6.66514465 Q9BYX7
P49588 -6.66516093 P49588
Q15907 -6.66525913 Q15907
Q9BZE4 -6.66528792 Q9BZE4
Q96EY7 -6.66533450 Q96EY7
Q96BI1 -6.66568334 Q96BI1
Q9UBC2 -6.66569970 Q9UBC2
Q96HC4 -6.66575122 Q96HC4
Q8N2U0 -6.66577375 Q8N2U0
P50336 -6.66630569 P50336
P55268 -6.66634672 P55268
Q07065 -6.66637565 Q07065
Q9Y4F5 -6.66644990 Q9Y4F5
P25490 -6.66647229 P25490
Q15334 -6.66660972 Q15334
O75094 -6.66661907 O75094
Q13061 -6.66692468 Q13061
Q9Y3B3 -6.66698708 Q9Y3B3
Q9BV10 -6.66699978 Q9BV10
Q9HAU0 -6.66733760 Q9HAU0
Q8N7X1 -6.66744771 Q8N7X1
O60831 -6.66749804 O60831
Q9P253 -6.66767915 Q9P253
P05161 -6.66772836 P05161
Q8IUR5 -6.66797654 Q8IUR5
Q5TEU4 -6.66798393 Q5TEU4
P49720 -6.66817229 P49720
P61803 -6.66852418 P61803
Q969N2 -6.66862780 Q969N2
O95563 -6.66868489 O95563
Q15796 -6.66899331 Q15796
P08574 -6.66926386 P08574
Q13363 -6.66954799 Q13363
Q96MR6 -6.66956012 Q96MR6
P05787 -6.66991499 P05787
Q14118 -6.66996813 Q14118
Q9UIA9 -6.67019059 Q9UIA9
P48047 -6.67023407 P48047
Q99523 -6.67029209 Q99523
P12955 -6.67032711 P12955
P35221 -6.67047281 P35221
Q9Y2Z4 -6.67090162 Q9Y2Z4
Q9NPH0 -6.67090476 Q9NPH0
Q8TCT9 -6.67102192 Q8TCT9
Q9BVG9 -6.67114321 Q9BVG9
Q05682 -6.67117968 Q05682
P51149 -6.67126030 P51149
A6NHR9 -6.67137354 A6NHR9
P29317 -6.67210266 P29317
Q01973 -6.67228803 Q01973
Q16854 -6.67242588 Q16854
O00754 -6.67261721 O00754
P31946 -6.67282667 P31946
Q5RI15 -6.67317695 Q5RI15
P59998 -6.67323143 P59998
P62877 -6.67327833 P62877
O15042 -6.67340809 O15042
P49773 -6.67370984 P49773
Q96I59 -6.67373229 Q96I59
P22102 -6.67428004 P22102
P30536 -6.67434693 P30536
Q7L1Q6 -6.67498551 Q7L1Q6
Q6YP21 -6.67518183 Q6YP21
Q6PI78 -6.67521567 Q6PI78
Q13332 -6.67524336 Q13332
Q6BDS2 -6.67526194 Q6BDS2
Q8TBP6 -6.67537664 Q8TBP6
Q01105 -6.67539271 Q01105
P35232 -6.67568566 P35232
Q9Y6I9 -6.67578960 Q9Y6I9
P21439 -6.67626975 P21439
Q92973 -6.67628555 Q92973
Q9BVV7 -6.67629846 Q9BVV7
O95819 -6.67646056 O95819
Q9BYF1 -6.67653348 Q9BYF1
P67870 -6.67685915 P67870
Q9NVD7 -6.67688356 Q9NVD7
P61457 -6.67708111 P61457
Q9BZQ8 -6.67763609 Q9BZQ8
P35606 -6.67765335 P35606
A3KMH1 -6.67785072 A3KMH1
O14874 -6.67824882 O14874
O95299 -6.67825533 O95299
Q9Y276 -6.67827579 Q9Y276
Q14847 -6.67845274 Q14847
Q96J01 -6.67853106 Q96J01
P54886 -6.67864819 P54886
Q13825 -6.67870806 Q13825
Q9BX67 -6.67898522 Q9BX67
Q9UDW1 -6.67902933 Q9UDW1
Q8TDJ6 -6.67905501 Q8TDJ6
Q9Y646 -6.67930871 Q9Y646
Q14318 -6.67940234 Q14318
O15235 -6.67948767 O15235
Q9UHN1 -6.67950182 Q9UHN1
Q9UI09 -6.67965255 Q9UI09
Q8TBZ3 -6.67975606 Q8TBZ3
O00746 -6.68004520 O00746
Q15120 -6.68005973 Q15120
P49754 -6.68032439 P49754
O95573 -6.68056801 O95573
Q8N1G4 -6.68076587 Q8N1G4
Q9H9S3 -6.68078062 Q9H9S3
P26678 -6.68084373 P26678
Q15392 -6.68091961 Q15392
P13010 -6.68094368 P13010
Q00587 -6.68114155 Q00587
P05089 -6.68125589 P05089
Q09666 -6.68127671 Q09666
Q86SQ0 -6.68129963 Q86SQ0
P50416 -6.68137121 P50416
Q0VGL1 -6.68169962 Q0VGL1
O75475 -6.68186049 O75475
P01023 -6.68200959 P01023
Q9ULV4 -6.68223283 Q9ULV4
P35270 -6.68228840 P35270
P02545 -6.68261232 P02545
P61421 -6.68287321 P61421
P20340 -6.68292993 P20340
Q9BQA9 -6.68296989 Q9BQA9
P25789 -6.68297394 P25789
Q9BXW7 -6.68297834 Q9BXW7
Q9UKE5 -6.68311695 Q9UKE5
O94973 -6.68313760 O94973
Q96MW7 -6.68321332 Q96MW7
P57105 -6.68323042 P57105
P61009 -6.68335569 P61009
Q9H2H9 -6.68357186 Q9H2H9
Q9H6E4 -6.68367074 Q9H6E4
Q8N9W4 -6.68376431 Q8N9W4
Q8NE71 -6.68379203 Q8NE71
Q9NZN4 -6.68402149 Q9NZN4
Q8TEM1 -6.68409525 Q8TEM1
O43819 -6.68424157 O43819
Q12846 -6.68426216 Q12846
P07355 -6.68433946 P07355
Q6P0N0 -6.68434442 Q6P0N0
Q6P1M3 -6.68441100 Q6P1M3
Q13177 -6.68486851 Q13177
Q9Y4G6 -6.68497857 Q9Y4G6
Q5SV97 -6.68525065 Q5SV97
O75907 -6.68530421 O75907
P47897 -6.68538768 P47897
P63000 -6.68545309 P63000
Q96G01 -6.68550981 Q96G01
Q9NTK5 -6.68556914 Q9NTK5
Q86UP2 -6.68561091 Q86UP2
O95479 -6.68569411 O95479
P30084 -6.68596308 P30084
Q9NRV9 -6.68611156 Q9NRV9
P62805 -6.68625434 P62805
P10301 -6.68627848 P10301
O43684 -6.68629656 O43684
Q14155 -6.68650427 Q14155
Q8TD19 -6.68707051 Q8TD19
P69905 -6.68710888 P69905
O14958 -6.68717221 O14958
Q15560 -6.68721096 Q15560
Q9Y6N5 -6.68723296 Q9Y6N5
O76003 -6.68732615 O76003
Q9BR39 -6.68740344 Q9BR39
Q5TAQ9 -6.68754959 Q5TAQ9
Q96E39 -6.68758877 Q96E39
P61204 -6.68767790 P61204
Q14934 -6.68775350 Q14934
Q15005 -6.68785432 Q15005
Q9C0D9 -6.68787655 Q9C0D9
Q9Y320 -6.68805428 Q9Y320
P11498 -6.68820123 P11498
O60763 -6.68821359 O60763
P33993 -6.68828606 P33993
Q86VU5 -6.68832651 Q86VU5
P35998 -6.68832671 P35998
O75369 -6.68833841 O75369
Q9P2R3 -6.68838049 Q9P2R3
P20618 -6.68842760 P20618
Q5XKP0 -6.68857814 Q5XKP0
P51809 -6.68874855 P51809
O15228 -6.68882366 O15228
P46939 -6.68892248 P46939
P04062 -6.68910404 P04062
P09382 -6.68917174 P09382
P27694 -6.68917250 P27694
O00462 -6.68918882 O00462
P22307 -6.68920385 P22307
Q9NZM3 -6.68933782 Q9NZM3
P34931 -6.68935613 P34931
P16219 -6.68938626 P16219
P00734 -6.68945851 P00734
Q9BS26 -6.68948668 Q9BS26
Q14974 -6.68951542 Q14974
Q9UN42 -6.68956460 Q9UN42
P50402 -6.68958473 P50402
P01112 -6.68958627 P01112
Q9NUM4 -6.68963639 Q9NUM4
Q9BWM7 -6.68967489 Q9BWM7
Q969M1 -6.68970816 Q969M1
P05166 -6.68977902 P05166
Q8N2H3 -6.68985476 Q8N2H3
P46060 -6.68989407 P46060
P24043 -6.68998443 P24043
P13051 -6.69000860 P13051
Q02252 -6.69001724 Q02252
Q8NFH5 -6.69009858 Q8NFH5
Q9UBM7 -6.69010847 Q9UBM7
Q9NVT9 -6.69013918 Q9NVT9
Q15691 -6.69014454 Q15691
Q15070 -6.69033023 Q15070
P06865 -6.69035875 P06865
Q4G176 -6.69061271 Q4G176
P00761 -6.69068284 P00761
O00425 -6.69076150 O00425
Q02127 -6.69076719 Q02127
P08F94 -6.69078448 P08F94
Q14677 -6.69080079 Q14677
P08651 -6.69082557 P08651
P28066 -6.69084298 P28066
Q14249 -6.69086075 Q14249
Q9UDY2 -6.69086532 Q9UDY2
Q99755 -6.69088038 Q99755
Q9Y2P4 -6.69097385 Q9Y2P4
P63165 -6.69109324 P63165
Q9NYK1 -6.69110624 Q9NYK1
Q9H019 -6.69112428 Q9H019
Q8TDY8 -6.69116696 Q8TDY8
Q9NYF8 -6.69122770 Q9NYF8
Q9HD23 -6.69122883 Q9HD23
P48723 -6.69127780 P48723
Q99594 -6.69133784 Q99594
Q9Y2U8 -6.69135234 Q9Y2U8
O75027 -6.69150937 O75027
Q5SSJ5 -6.69153115 Q5SSJ5
O75400 -6.69155681 O75400
P31327 -6.69157278 P31327
Q9Y2A7 -6.69161165 Q9Y2A7
Q9UID3 -6.69164571 Q9UID3
P14543 -6.69167506 P14543
P17152 -6.69168105 P17152
Q13620 -6.69191089 Q13620
P29992 -6.69192112 P29992
Q5T2T1 -6.69199239 Q5T2T1
P62140 -6.69211127 P62140
Q969V3 -6.69212247 Q969V3
O75063 -6.69213893 O75063
O43765 -6.69215745 O43765
Q8N2F6 -6.69231021 Q8N2F6
Q8WVX9 -6.69253481 Q8WVX9
Q14139 -6.69266565 Q14139
P82933 -6.69277252 P82933
Q01813 -6.69278228 Q01813
Q9BX66 -6.69283060 Q9BX66
P60891 -6.69285752 P60891
P11021 -6.69287675 P11021
Q9NSV4 -6.69288702 Q9NSV4
P02786 -6.69294390 P02786
Q15075 -6.69298100 Q15075
P50440 -6.69300586 P50440
Q96ER9 -6.69303097 Q96ER9
Q9H0V9 -6.69306287 Q9H0V9
Q96SJ8 -6.69313652 Q96SJ8
Q9UDR5 -6.69324836 Q9UDR5
Q99436 -6.69329334 Q99436
P07910 -6.69330329 P07910
P43121 -6.69330548 P43121
Q969Z3 -6.69332901 Q969Z3
Q9P291 -6.69333111 Q9P291
Q96I51 -6.69335664 Q96I51
P12270 -6.69338531 P12270
P62993 -6.69341311 P62993
O43852 -6.69341501 O43852
O00186 -6.69354640 O00186
P61020 -6.69357300 P61020
Q9UJW0 -6.69365387 Q9UJW0
P50213 -6.69367977 P50213
P13861 -6.69370506 P13861
Q8NDZ4 -6.69373159 Q8NDZ4
P35659 -6.69374169 P35659
P56747 -6.69375129 P56747
O95861 -6.69376458 O95861
Q68D91 -6.69382280 Q68D91
Q96D53 -6.69384693 Q96D53
Q9GZP0 -6.69384718 Q9GZP0
Q9UBX3 -6.69386800 Q9UBX3
Q6Y288 -6.69388580 Q6Y288
Q58EX2 -6.69391048 Q58EX2
Q9P035 -6.69391067 Q9P035
Q92614 -6.69393105 Q92614
O75376 -6.69395546 O75376
O43615 -6.69399068 O43615
O43169 -6.69399391 O43169
Q6UW68 -6.69403286 Q6UW68
P35968 -6.69403495 P35968
Q9GZY4 -6.69404913 Q9GZY4
Q8IZQ5 -6.69407310 Q8IZQ5
O60841 -6.69408020 O60841
P28288 -6.69409240 P28288
O75417 -6.69415329 O75417
Q15067 -6.69417614 Q15067
P26368 -6.69421171 P26368
P23919 -6.69421245 P23919
Q155Q3 -6.69422554 Q155Q3
Q13232 -6.69422754 Q13232
Q6FI81 -6.69423719 Q6FI81
O00505 -6.69428425 O00505
Q15008 -6.69429821 Q15008
O00743 -6.69430938 O00743
Q32P44 -6.69435312 Q32P44
P78417 -6.69436435 P78417
P14621 -6.69437287 P14621
Q9BYD1 -6.69438001 Q9BYD1
P61586 -6.69439056 P61586
Q14566 -6.69439736 Q14566
P10915 -6.69440748 P10915
Q9BXS5 -6.69443460 Q9BXS5
Q6P1M0 -6.69444145 Q6P1M0
Q9C0D5 -6.69444293 Q9C0D5
Q15185 -6.69444902 Q15185
P51153 -6.69445018 P51153
P29144 -6.69445665 P29144
P09543 -6.69447856 P09543
Q9BZF1 -6.69448357 Q9BZF1
Q92538 -6.69448566 Q92538
Q96N64 -6.69448651 Q96N64
Q52LJ0 -6.69448746 Q52LJ0
P54753 -6.69448773 P54753Q-Values
qobj <- qvalue(toptable_Dupcor$P.Value)
adj_q_values <- qobj$qvalues
toptable_Dupcor$adj_q_values <- adj_q_values
toptable_Dupcor logFC AveExpr t P.Value adj.P.Val
Q15327 -3.5538167761 23.99047 -16.743392583 2.054348e-08 6.951913e-05
O76021 -2.1410928975 24.25375 -13.552273075 1.444049e-07 2.443330e-04
Q96LW7 -1.6342957224 19.97143 -12.658156240 2.690260e-07 3.034614e-04
Q969Q1 -4.3423803749 20.84232 -11.920968346 4.632261e-07 3.918893e-04
P19388 -1.1658966201 20.44496 -11.622278836 5.822611e-07 3.940743e-04
Q96GQ7 -1.7622803092 20.67219 -10.833687964 1.092754e-06 6.163133e-04
O43159 -2.1096892264 20.56152 -10.318875713 1.684397e-06 8.142856e-04
Q6EMK4 2.3724491682 21.06129 9.656663573 3.021583e-06 1.278129e-03
P17844 -1.1425406345 25.94182 -9.304080076 4.181540e-06 1.572259e-03
Q96PU8 -2.1455298252 21.20691 -8.951039111 5.848963e-06 1.881965e-03
Q14498 -0.8019789647 23.53525 -8.890645629 6.201192e-06 1.881965e-03
P67809 -1.1045436713 26.08944 -8.774842757 6.943236e-06 1.881965e-03
Q9BQG0 -2.2554253126 23.65243 -8.733704263 7.229772e-06 1.881965e-03
P17480 0.7861550384 24.19823 8.375813153 1.034545e-05 2.500644e-03
Q13641 1.3614453777 21.17736 8.173707956 1.273359e-05 2.711717e-03
P48634 -1.0858313049 20.62697 -8.167089200 1.282136e-05 2.711717e-03
Q92841 -0.7539368895 27.56259 -8.106875865 1.365082e-05 2.717316e-03
Q4G0J3 -0.7752299178 23.21486 -7.930348626 1.643911e-05 3.007123e-03
P78347 -0.7435322555 26.03868 -7.905231639 1.688397e-05 3.007123e-03
Q02818 -2.3955560537 22.73869 -7.799179727 1.891244e-05 3.156765e-03
Q00341 -0.9058215272 24.57254 -7.751362535 1.991267e-05 3.156765e-03
Q13123 -1.1338838135 22.25040 -7.723467328 2.052270e-05 3.156765e-03
Q92522 -1.6536207267 24.17315 -7.487060032 2.659124e-05 3.912381e-03
Q14980 -1.2192370415 24.62561 -7.396873728 2.940013e-05 4.145419e-03
Q14694 -0.7674689571 22.72482 -7.315811636 3.220183e-05 4.358840e-03
Q2TAY7 -0.7632109180 23.97921 -7.246263013 3.483785e-05 4.534280e-03
Q9NR30 -1.0206069551 23.97933 -7.190152266 3.713578e-05 4.654352e-03
O60427 -1.2083869980 21.17097 -7.066908229 4.278320e-05 5.057106e-03
Q9P258 1.7059490390 21.25515 7.027127742 4.480026e-05 5.057106e-03
Q9Y6M5 1.1382005458 23.05230 6.992690129 4.662999e-05 5.057106e-03
Q9BVP2 -1.5081799250 21.49507 -6.984110085 4.709839e-05 5.057106e-03
Q9P0V3 -1.5653815562 20.47551 -6.971047875 4.782133e-05 5.057106e-03
Q6P5R6 -1.8797159229 20.65233 -6.877412686 5.337046e-05 5.472898e-03
Q92934 -1.2351650877 21.23559 -6.837172761 5.596677e-05 5.521477e-03
Q86XP3 -0.7285835498 23.65238 -6.820129601 5.710747e-05 5.521477e-03
O95864 -2.6174073619 19.59627 -6.761650756 6.121744e-05 5.610083e-03
Q9NZB2 -1.0158315089 23.24048 -6.739923968 6.282530e-05 5.610083e-03
Q9UQE7 -1.4794349461 20.76312 -6.737634433 6.299739e-05 5.610083e-03
Q6P1J9 -0.7979336434 22.49594 -6.581727353 7.601030e-05 6.595355e-03
P16989 -2.7782295557 21.60829 -6.515400547 8.240654e-05 6.971593e-03
Q9BZK7 -0.6448869669 22.87123 -6.451002969 8.917833e-05 7.360475e-03
P08865 -0.6951266140 26.40427 -6.412174570 9.355111e-05 7.537546e-03
P26640 0.5742911993 24.75172 6.360867386 9.968907e-05 7.845298e-03
Q96T58 1.2393881736 22.45091 6.330081073 1.035805e-04 7.847079e-03
Q13151 -0.7134418171 25.34094 -6.319602357 1.049423e-04 7.847079e-03
Q9Y2X3 0.6514755296 25.29422 6.306530078 1.066683e-04 7.847079e-03
Q13451 0.7026843452 19.60808 6.254442541 1.138575e-04 8.197740e-03
Q9UKA9 -0.7576536433 24.34593 -6.213200990 1.199217e-04 8.454480e-03
P23434 0.9639278116 22.27141 6.180102278 1.250414e-04 8.635514e-03
Q9Y333 -1.6242843304 20.77853 -6.096218482 1.391064e-04 9.414723e-03
Q53EP0 -1.4507298032 22.03019 -6.016564592 1.540564e-04 1.022209e-02
P62906 -0.9477995132 25.76636 -5.964830968 1.646908e-04 1.029373e-02
P49711 -0.7460068993 21.19290 -5.956844911 1.664019e-04 1.029373e-02
P42285 -0.9617635928 22.20386 -5.956134822 1.665550e-04 1.029373e-02
Q16718 -0.6128746798 22.93208 -5.952672315 1.673036e-04 1.029373e-02
P62854 -1.7373368214 24.65941 -5.893289295 1.807240e-04 1.086007e-02
Q9BQ39 -1.1157407297 22.97953 -5.878742237 1.841859e-04 1.086007e-02
P62750 -1.1141546927 24.69063 -5.870677397 1.861359e-04 1.086007e-02
Q9H2P0 -1.0743673769 22.07434 -5.826142783 1.973134e-04 1.116432e-02
Q49A26 0.8520902429 22.17348 5.820374572 1.988134e-04 1.116432e-02
Q9UQB8 1.1594641852 22.29025 5.811110965 2.012480e-04 1.116432e-02
Q96L96 -1.7454620125 20.94368 -5.758472970 2.157071e-04 1.177343e-02
P62753 -0.6301099885 25.90518 -5.711233343 2.296400e-04 1.233495e-02
P16403 -1.5769850831 25.04572 -5.631674350 2.553465e-04 1.325802e-02
P62273 -0.7268629014 22.25772 -5.625972328 2.573044e-04 1.325802e-02
Q99536 0.7708229050 24.87540 5.615690534 2.608759e-04 1.325802e-02
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P04062 -0.0186540967 23.81559 -0.099522119 9.227755e-01 9.633472e-01
P09382 -0.0307928569 25.49314 -0.098894180 9.232610e-01 9.633472e-01
P27694 0.0277877963 24.86406 0.098887044 9.232665e-01 9.633472e-01
O00462 -0.0097998990 25.08341 -0.098735102 9.233840e-01 9.633472e-01
P22307 -0.0145158437 25.76061 -0.098594857 9.234924e-01 9.633472e-01
Q9NZM3 0.0221290468 23.74942 0.097336464 9.244655e-01 9.636073e-01
P34931 -0.0198052635 24.65605 -0.097163206 9.245995e-01 9.636073e-01
P16219 -0.0142894513 24.99126 -0.096877470 9.248205e-01 9.636073e-01
P00734 -0.0218670313 20.79997 -0.096188763 9.253531e-01 9.636073e-01
Q9BS26 0.0118885102 26.53071 0.095918890 9.255618e-01 9.636073e-01
Q14974 0.0091638057 26.60580 0.095642815 9.257753e-01 9.636073e-01
Q9UN42 0.0529851700 24.44938 0.095168421 9.261423e-01 9.636073e-01
P50402 -0.0092716097 25.43118 -0.094973649 9.262929e-01 9.636073e-01
P01112 0.0135000733 24.14441 0.094958654 9.263045e-01 9.636073e-01
Q9NUM4 0.0223334393 22.01896 0.094471818 9.266811e-01 9.636750e-01
Q9BWM7 0.0217927237 24.70386 0.094096025 9.269718e-01 9.636750e-01
Q969M1 0.0210633620 21.82823 0.093770125 9.272239e-01 9.636750e-01
P05166 0.0107373080 25.22551 0.093072210 9.277638e-01 9.639401e-01
Q8N2H3 0.0407270612 23.71033 0.092320385 9.283455e-01 9.642394e-01
P46060 0.0101036945 22.55457 0.091927779 9.286493e-01 9.642394e-01
P24043 -0.0286933388 22.52164 -0.091018854 9.293526e-01 9.642394e-01
P13051 -0.0239032109 20.23308 -0.090774256 9.295419e-01 9.642394e-01
Q02252 0.0114156845 26.84969 0.090686632 9.296097e-01 9.642394e-01
Q8NFH5 -0.0086793530 20.80922 -0.089857588 9.302513e-01 9.642394e-01
Q9UBM7 0.0265568097 24.51966 0.089756303 9.303297e-01 9.642394e-01
Q9NVT9 -0.0695866795 24.16418 -0.089440953 9.305737e-01 9.642394e-01
Q15691 -0.0244255009 23.41869 -0.089385757 9.306164e-01 9.642394e-01
Q15070 -0.0250575927 24.80790 -0.087453602 9.321120e-01 9.654389e-01
P06865 0.0111440839 24.87987 0.087153035 9.323446e-01 9.654389e-01
Q4G176 -0.0116557149 24.14503 -0.084429697 9.344531e-01 9.667488e-01
P00761 0.0096551066 31.08365 0.083661976 9.350476e-01 9.667488e-01
O00425 -0.0088968604 26.12775 -0.082792556 9.357208e-01 9.667488e-01
Q02127 0.0119945538 22.14724 0.082729316 9.357698e-01 9.667488e-01
P08F94 -0.0186971056 21.20035 -0.082536801 9.359189e-01 9.667488e-01
Q14677 0.0118688959 20.45310 0.082354795 9.360599e-01 9.667488e-01
P08651 -0.0121724593 20.69112 -0.082077547 9.362746e-01 9.667488e-01
P28066 0.0076420581 24.33706 0.081882140 9.364259e-01 9.667488e-01
Q14249 0.0095893912 24.57991 0.081682259 9.365807e-01 9.667488e-01
Q9UDY2 -0.0253243845 20.15616 -0.081630790 9.366206e-01 9.667488e-01
Q99755 0.0418349618 18.76583 0.081460879 9.367522e-01 9.667488e-01
Q9Y2P4 0.0127607804 24.04330 0.080398436 9.375751e-01 9.673031e-01
P63165 0.0123175233 21.71677 0.079020619 9.386425e-01 9.678086e-01
Q9NYK1 -0.0498251988 23.31318 -0.078869131 9.387598e-01 9.678086e-01
Q9H019 -0.0092611101 22.90488 -0.078658462 9.389230e-01 9.678086e-01
Q8TDY8 -0.0426163562 19.12771 -0.078157765 9.393109e-01 9.679082e-01
Q9NYF8 0.0085150296 25.65458 0.077439550 9.398674e-01 9.679082e-01
Q9HD23 0.0119060604 21.38225 0.077426125 9.398778e-01 9.679082e-01
P48723 -0.0102901119 22.73254 -0.076842096 9.403303e-01 9.680796e-01
Q99594 -0.0193135842 20.32437 -0.076120062 9.408898e-01 9.682065e-01
Q9Y2U8 0.0098060997 22.99646 0.075944555 9.410258e-01 9.682065e-01
O75027 -0.0099842542 24.53979 -0.074018291 9.425185e-01 9.691118e-01
Q5SSJ5 0.0073752285 26.66669 0.073747130 9.427287e-01 9.691118e-01
O75400 -0.0124379818 24.09084 -0.073426358 9.429773e-01 9.691118e-01
P31327 0.0136571174 23.68287 0.073226019 9.431326e-01 9.691118e-01
Q9Y2A7 0.0125353448 23.81438 0.072736143 9.435123e-01 9.691118e-01
Q9UID3 0.0295843740 19.75980 0.072304102 9.438472e-01 9.691118e-01
P14543 -0.0167919221 23.69376 -0.071929886 9.441372e-01 9.691118e-01
P17152 -0.0105953273 23.41777 -0.071853200 9.441967e-01 9.691118e-01
Q13620 0.0145089750 23.68199 0.068848276 9.465262e-01 9.710227e-01
P29992 -0.0064416056 25.11985 -0.068711426 9.466323e-01 9.710227e-01
Q5T2T1 0.0097889222 19.07726 0.067750831 9.473772e-01 9.714922e-01
P62140 0.0079203715 26.50835 0.066117357 9.486438e-01 9.721262e-01
Q969V3 -0.0091642882 24.65837 -0.065961302 9.487649e-01 9.721262e-01
O75063 -0.0196776515 20.88879 -0.065731441 9.489431e-01 9.721262e-01
O43765 -0.0198025217 25.84904 -0.065471807 9.491445e-01 9.721262e-01
Q8N2F6 -0.0198511112 22.52100 -0.063289545 9.508370e-01 9.735650e-01
Q8WVX9 0.0060289228 18.79905 0.059937211 9.534375e-01 9.759324e-01
Q14139 -0.0057615311 22.36123 -0.057894924 9.550221e-01 9.772588e-01
P82933 0.0054829992 25.65392 0.056171698 9.563593e-01 9.781625e-01
Q01813 0.0167370873 27.35581 0.056011786 9.564834e-01 9.781625e-01
Q9BX66 0.0143358680 21.78936 0.055212659 9.571035e-01 9.783663e-01
P60891 0.0067843410 25.93807 0.054762504 9.574529e-01 9.783663e-01
P11021 0.0063562359 30.65990 0.054438581 9.577043e-01 9.783663e-01
Q9NSV4 0.0171790228 18.90526 0.054264910 9.578391e-01 9.783663e-01
P02786 0.0070610326 28.18432 0.053292307 9.585939e-01 9.788418e-01
Q15075 0.0050036274 26.59854 0.052648238 9.590938e-01 9.790569e-01
P50440 0.0143064229 23.95149 0.052212300 9.594322e-01 9.791069e-01
Q96ER9 -0.0102512056 22.44630 -0.051768147 9.597770e-01 9.791635e-01
Q9H0V9 -0.0093153054 23.67906 -0.051198399 9.602192e-01 9.793194e-01
Q96SJ8 -0.0156754084 21.16539 -0.049857987 9.612597e-01 9.800853e-01
Q9UDR5 0.0064776062 26.72489 0.047750841 9.628956e-01 9.812624e-01
Q99436 0.0067940073 24.84376 0.046876834 9.635742e-01 9.812624e-01
P07910 0.0061472861 25.80692 0.046681226 9.637261e-01 9.812624e-01
P43121 0.0072381493 25.74715 0.046638044 9.637596e-01 9.812624e-01
Q969Z3 -0.0054001601 25.20349 -0.046171842 9.641216e-01 9.812624e-01
Q9P291 0.0057158178 25.18091 0.046130028 9.641541e-01 9.812624e-01
Q96I51 -0.0099153320 22.36944 -0.045618276 9.645514e-01 9.813716e-01
P12270 -0.0063074599 25.52478 -0.045036686 9.650030e-01 9.814281e-01
P62993 -0.0191703184 21.93934 -0.044465395 9.654466e-01 9.814281e-01
O43852 -0.0066212747 26.73698 -0.044426234 9.654770e-01 9.814281e-01
O00186 -0.0047971737 24.18030 -0.041618048 9.676578e-01 9.833495e-01
P61020 0.0097273667 23.77504 0.041026201 9.681174e-01 9.835213e-01
Q9UJW0 -0.0059093156 21.61949 -0.039172094 9.695575e-01 9.846886e-01
P50213 -0.0051954398 29.24408 -0.038559279 9.700335e-01 9.848765e-01
P13861 -0.0050914180 25.47757 -0.037951567 9.705055e-01 9.850378e-01
Q8NDZ4 -0.0086632938 22.12834 -0.037303220 9.710091e-01 9.850378e-01
P35659 -0.0044616574 24.57097 -0.037053420 9.712032e-01 9.850378e-01
P56747 0.0187623726 22.70278 0.036814390 9.713888e-01 9.850378e-01
O95861 -0.0054869445 21.62864 -0.036481025 9.716478e-01 9.850378e-01
Q68D91 -0.0095284586 21.60360 -0.034982953 9.728115e-01 9.858407e-01
Q96D53 -0.0072857034 21.18247 -0.034343139 9.733086e-01 9.858407e-01
Q9GZP0 0.0175080541 19.10221 0.034336389 9.733138e-01 9.858407e-01
Q9UBX3 -0.0059197351 24.59611 -0.033774291 9.737505e-01 9.859879e-01
Q6Y288 0.0073062541 19.45079 0.033286033 9.741298e-01 9.860329e-01
Q58EX2 0.0102423104 20.21960 0.032597398 9.746648e-01 9.860329e-01
Q9P035 -0.0044522294 24.84269 -0.032591930 9.746690e-01 9.860329e-01
Q92614 -0.0028647118 27.76244 -0.032011880 9.751197e-01 9.861940e-01
O75376 0.0074416599 21.25635 0.031302942 9.756705e-01 9.864562e-01
O43615 0.0037622817 26.76185 0.030250962 9.764878e-01 9.867703e-01
O43169 0.0032027964 25.40996 0.030152532 9.765643e-01 9.867703e-01
Q6UW68 0.0046572920 24.02324 0.028940720 9.775059e-01 9.871844e-01
P35968 0.0047097694 22.81438 0.028874123 9.775576e-01 9.871844e-01
Q9GZY4 -0.0055021156 22.45684 -0.028419001 9.779113e-01 9.872469e-01
Q8IZQ5 0.0066248105 21.22786 0.027632841 9.785221e-01 9.874605e-01
O60841 -0.0035220559 23.29606 -0.027395651 9.787065e-01 9.874605e-01
P28288 -0.0036256509 25.16783 -0.026983209 9.790269e-01 9.874895e-01
O75417 0.0054159815 22.72883 0.024822018 9.807064e-01 9.888887e-01
Q15067 0.0044210791 24.49190 0.023960695 9.813757e-01 9.892688e-01
P26368 -0.0022281622 25.59537 -0.022554523 9.824685e-01 9.897040e-01
P23919 -0.0032968988 23.83964 -0.022524558 9.824918e-01 9.897040e-01
Q155Q3 0.0028108220 19.49408 0.021983738 9.829121e-01 9.897040e-01
Q13232 -0.0035464856 23.30546 -0.021899863 9.829773e-01 9.897040e-01
Q6FI81 0.0039575492 22.46627 0.021490816 9.832952e-01 9.897296e-01
O00505 0.0085658006 21.80293 0.019373553 9.849407e-01 9.910911e-01
Q15008 0.0024531736 24.84515 0.018699420 9.854646e-01 9.913235e-01
O00743 -0.0030229107 20.62747 -0.018142189 9.858977e-01 9.914644e-01
Q32P44 -0.0035448747 20.06958 -0.015770667 9.877410e-01 9.930230e-01
P78417 0.0018041193 23.56780 0.015101749 9.882609e-01 9.932506e-01
P14621 -0.0045005530 20.78173 -0.014573761 9.886713e-01 9.933680e-01
Q9BYD1 0.0015316464 24.46061 0.014116314 9.890268e-01 9.934303e-01
P61586 0.0013072005 26.74816 0.013411483 9.895747e-01 9.936857e-01
Q14566 0.0021581420 23.68538 0.012937085 9.899434e-01 9.937611e-01
P10915 0.0050398203 23.61243 0.012197305 9.905185e-01 9.940434e-01
Q9BXS5 -0.0015175385 22.77994 -0.009945018 9.922692e-01 9.955052e-01
Q6P1M0 -0.0013230822 22.76586 -0.009290689 9.927778e-01 9.955410e-01
Q9C0D5 0.0037181052 19.95329 0.009142181 9.928933e-01 9.955410e-01
Q15185 0.0008048923 24.10663 0.008508503 9.933859e-01 9.955435e-01
P51153 0.0012681861 22.33613 0.008381986 9.934842e-01 9.955435e-01
P29144 0.0012070742 25.09501 0.007639958 9.940610e-01 9.958267e-01
P09543 0.0006074187 25.46963 0.004251034 9.966954e-01 9.981702e-01
Q9BZF1 -0.0006529423 22.69373 -0.002977151 9.976857e-01 9.988664e-01
Q92538 0.0002573516 22.84061 0.002240344 9.982584e-01 9.991413e-01
Q96N64 -0.0002124377 21.72457 -0.001860990 9.985533e-01 9.991413e-01
Q52LJ0 -0.0003543919 23.01653 -0.001309060 9.989824e-01 9.991413e-01
P54753 -0.0002160733 24.88610 -0.001104627 9.991413e-01 9.991413e-01
B Protein adj_q_values
Q15327 9.41678906 Q15327 3.487221e-05
O76021 7.85938218 O76021 1.225624e-04
Q96LW7 7.32858329 Q96LW7 1.522224e-04
Q969Q1 6.85315287 Q969Q1 1.965796e-04
P19388 6.64995911 P19388 1.976757e-04
Q96GQ7 6.08177746 Q96GQ7 3.091553e-04
O43159 5.68418526 O43159 4.084622e-04
Q6EMK4 5.13889238 Q6EMK4 6.411357e-04
P17844 4.83188794 P17844 7.886770e-04
Q96PU8 4.51212370 Q96PU8 9.440320e-04
Q14498 4.45613928 Q14498 9.440320e-04
P67809 4.34771600 P67809 9.440320e-04
Q9BQG0 4.30885560 Q9BQG0 9.440320e-04
P17480 3.96300337 P17480 1.254374e-03
Q13641 3.76135899 Q13641 1.360252e-03
P48634 3.75467595 P48634 1.360252e-03
Q92841 3.69364382 Q92841 1.363061e-03
Q4G0J3 3.51225902 Q4G0J3 1.508434e-03
P78347 3.48614960 P78347 1.508434e-03
Q02818 3.37506845 Q02818 1.583497e-03
Q00341 3.32453644 Q00341 1.583497e-03
Q13123 3.29492808 Q13123 1.583497e-03
Q92522 3.04012137 Q92522 1.962530e-03
Q14980 2.94105844 Q14980 2.079426e-03
Q14694 2.85112708 Q14694 2.186483e-03
Q2TAY7 2.77329003 Q2TAY7 2.274487e-03
Q9NR30 2.71003141 Q9NR30 2.334717e-03
O60427 2.56962788 O60427 2.536747e-03
Q9P258 2.52387666 Q9P258 2.536747e-03
Q9Y6M5 2.48409864 Q9Y6M5 2.536747e-03
Q9BVP2 2.47416318 Q9BVP2 2.536747e-03
Q9P0V3 2.45901842 Q9P0V3 2.536747e-03
Q6P5R6 2.34977722 Q6P5R6 2.745317e-03
Q92934 2.30246324 Q92934 2.769685e-03
Q86XP3 2.28235699 Q86XP3 2.769685e-03
O95864 2.21306382 O95864 2.814132e-03
Q9NZB2 2.18719870 Q9NZB2 2.814132e-03
Q9UQE7 2.18446927 Q9UQE7 2.814132e-03
Q6P1J9 1.99688564 Q6P1J9 3.308364e-03
P16989 1.91604606 P16989 3.497093e-03
Q9BZK7 1.83695990 Q9BZK7 3.692164e-03
P08865 1.78898876 P08865 3.780986e-03
P26640 1.72526854 P26640 3.935361e-03
Q96T58 1.68685180 Q96T58 3.936254e-03
Q13151 1.67374468 Q13151 3.936254e-03
Q9Y2X3 1.65737116 Q9Y2X3 3.936254e-03
Q13451 1.59188333 Q13451 4.112153e-03
Q9UKA9 1.53975167 Q9UKA9 4.240939e-03
P23434 1.49773330 P23434 4.331749e-03
Q9Y333 1.39052408 Q9Y333 4.722616e-03
Q53EP0 1.28776035 Q53EP0 5.127610e-03
P62906 1.22051338 P62906 5.163545e-03
P49711 1.21009707 P49711 5.163545e-03
P42285 1.20917043 P42285 5.163545e-03
Q16718 1.20465092 Q16718 5.163545e-03
P62854 1.12686153 P62854 5.447631e-03
Q9BQ39 1.10772508 Q9BQ39 5.447631e-03
P62750 1.09710225 P62750 5.447631e-03
Q9H2P0 1.03826658 Q9H2P0 5.600247e-03
Q49A26 1.03062429 Q49A26 5.600247e-03
Q9UQB8 1.01834049 Q9UQB8 5.600247e-03
Q96L96 0.94829592 Q96L96 5.905794e-03
P62753 0.88507921 P62753 6.187460e-03
P16403 0.77784969 P16403 6.650491e-03
P62273 0.77012769 P62273 6.650491e-03
Q99536 0.75619104 Q99536 6.650491e-03
Q06136 0.74993066 Q06136 6.650491e-03
Q9UQ35 0.69915601 Q9UQ35 6.655352e-03
Q96RU2 0.69591532 Q96RU2 6.655352e-03
P61254 0.68926951 P61254 6.655352e-03
Q14728 0.67697163 Q14728 6.655352e-03
Q9H1E3 0.67640450 Q9H1E3 6.655352e-03
Q86U42 0.64251694 Q86U42 6.689712e-03
P61313 0.62262994 P61313 6.689712e-03
Q01780 0.61237014 Q01780 6.689712e-03
P46782 0.60769103 P46782 6.689712e-03
Q9HCM4 0.58420148 Q9HCM4 6.689712e-03
P30876 0.57809873 P30876 6.689712e-03
P39880 0.57080739 P39880 6.689712e-03
Q9NQT5 0.56458543 Q9NQT5 6.689712e-03
P62280 0.54023271 P62280 6.768010e-03
P62701 0.52350618 P62701 6.796854e-03
Q92747 0.45129299 Q92747 7.145565e-03
P36578 0.44844527 P36578 7.145565e-03
P62888 0.43322923 P62888 7.168392e-03
Q5QJ74 0.40332925 Q5QJ74 7.267940e-03
O75787 0.39570237 O75787 7.267940e-03
P49207 0.35515105 P49207 7.478794e-03
Q9P0M6 0.31904160 Q9P0M6 7.581754e-03
Q6Y7W6 0.31852563 Q6Y7W6 7.581754e-03
Q7Z739 0.30701565 Q7Z739 7.584092e-03
Q8NC51 0.28873536 Q8NC51 7.638198e-03
P18621 0.25873195 P18621 7.727127e-03
O00461 0.25520586 O00461 7.727127e-03
P46783 0.24154596 P46783 7.749522e-03
P19338 0.22056090 P19338 7.829207e-03
P53396 0.18985383 P53396 7.986778e-03
Q99459 0.17312946 Q99459 8.036761e-03
Q9Y5S2 0.14548965 Q9Y5S2 8.175425e-03
Q9Y2I6 0.08497617 Q9Y2I6 8.591324e-03
O60292 0.03814180 O60292 8.802806e-03
P61513 0.03568548 P61513 8.802806e-03
Q13509 0.03032847 Q13509 8.802806e-03
Q9NVP1 -0.03024043 Q9NVP1 9.254525e-03
P62263 -0.04153371 P62263 9.268987e-03
P16220 -0.09251412 P16220 9.654642e-03
Q9UKU7 -0.14010475 Q9UKU7 9.934553e-03
P34932 -0.14048551 P34932 9.934553e-03
P83731 -0.15966101 P83731 1.003117e-02
P62249 -0.17003751 P62249 1.004212e-02
P25398 -0.21961283 P25398 1.018428e-02
Q12983 -0.21984771 Q12983 1.018428e-02
P07996 -0.22641025 P07996 1.018428e-02
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P05166 -6.68977902 P05166 4.835319e-01
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P46060 -6.68989407 P46060 4.836821e-01
P24043 -6.68998443 P24043 4.836821e-01
P13051 -6.69000860 P13051 4.836821e-01
Q02252 -6.69001724 Q02252 4.836821e-01
Q8NFH5 -6.69009858 Q8NFH5 4.836821e-01
Q9UBM7 -6.69010847 Q9UBM7 4.836821e-01
Q9NVT9 -6.69013918 Q9NVT9 4.836821e-01
Q15691 -6.69014454 Q15691 4.836821e-01
Q15070 -6.69033023 Q15070 4.842837e-01
P06865 -6.69035875 P06865 4.842837e-01
Q4G176 -6.69061271 Q4G176 4.849408e-01
P00761 -6.69068284 P00761 4.849408e-01
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P08F94 -6.69078448 P08F94 4.849408e-01
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P08651 -6.69082557 P08651 4.849408e-01
P28066 -6.69084298 P28066 4.849408e-01
Q14249 -6.69086075 Q14249 4.849408e-01
Q9UDY2 -6.69086532 Q9UDY2 4.849408e-01
Q99755 -6.69088038 Q99755 4.849408e-01
Q9Y2P4 -6.69097385 Q9Y2P4 4.852189e-01
P63165 -6.69109324 P63165 4.854724e-01
Q9NYK1 -6.69110624 Q9NYK1 4.854724e-01
Q9H019 -6.69112428 Q9H019 4.854724e-01
Q8TDY8 -6.69116696 Q8TDY8 4.855224e-01
Q9NYF8 -6.69122770 Q9NYF8 4.855224e-01
Q9HD23 -6.69122883 Q9HD23 4.855224e-01
P48723 -6.69127780 P48723 4.856084e-01
Q99594 -6.69133784 Q99594 4.856720e-01
Q9Y2U8 -6.69135234 Q9Y2U8 4.856720e-01
O75027 -6.69150937 O75027 4.861262e-01
Q5SSJ5 -6.69153115 Q5SSJ5 4.861262e-01
O75400 -6.69155681 O75400 4.861262e-01
P31327 -6.69157278 P31327 4.861262e-01
Q9Y2A7 -6.69161165 Q9Y2A7 4.861262e-01
Q9UID3 -6.69164571 Q9UID3 4.861262e-01
P14543 -6.69167506 P14543 4.861262e-01
P17152 -6.69168105 P17152 4.861262e-01
Q13620 -6.69191089 Q13620 4.870847e-01
P29992 -6.69192112 P29992 4.870847e-01
Q5T2T1 -6.69199239 Q5T2T1 4.873202e-01
P62140 -6.69211127 P62140 4.876382e-01
Q969V3 -6.69212247 Q969V3 4.876382e-01
O75063 -6.69213893 O75063 4.876382e-01
O43765 -6.69215745 O43765 4.876382e-01
Q8N2F6 -6.69231021 Q8N2F6 4.883600e-01
Q8WVX9 -6.69253481 Q8WVX9 4.895475e-01
Q14139 -6.69266565 Q14139 4.902129e-01
P82933 -6.69277252 P82933 4.906662e-01
Q01813 -6.69278228 Q01813 4.906662e-01
Q9BX66 -6.69283060 Q9BX66 4.907684e-01
P60891 -6.69285752 P60891 4.907684e-01
P11021 -6.69287675 P11021 4.907684e-01
Q9NSV4 -6.69288702 Q9NSV4 4.907684e-01
P02786 -6.69294390 P02786 4.910069e-01
Q15075 -6.69298100 Q15075 4.911148e-01
P50440 -6.69300586 P50440 4.911399e-01
Q96ER9 -6.69303097 Q96ER9 4.911683e-01
Q9H0V9 -6.69306287 Q9H0V9 4.912465e-01
Q96SJ8 -6.69313652 Q96SJ8 4.916307e-01
Q9UDR5 -6.69324836 Q9UDR5 4.922211e-01
Q99436 -6.69329334 Q99436 4.922211e-01
P07910 -6.69330329 P07910 4.922211e-01
P43121 -6.69330548 P43121 4.922211e-01
Q969Z3 -6.69332901 Q969Z3 4.922211e-01
Q9P291 -6.69333111 Q9P291 4.922211e-01
Q96I51 -6.69335664 Q96I51 4.922759e-01
P12270 -6.69338531 P12270 4.923043e-01
P62993 -6.69341311 P62993 4.923043e-01
O43852 -6.69341501 O43852 4.923043e-01
O00186 -6.69354640 O00186 4.932681e-01
P61020 -6.69357300 P61020 4.933542e-01
Q9UJW0 -6.69365387 Q9UJW0 4.939398e-01
P50213 -6.69367977 P50213 4.940340e-01
P13861 -6.69370506 P13861 4.941149e-01
Q8NDZ4 -6.69373159 Q8NDZ4 4.941149e-01
P35659 -6.69374169 P35659 4.941149e-01
P56747 -6.69375129 P56747 4.941149e-01
O95861 -6.69376458 O95861 4.941149e-01
Q68D91 -6.69382280 Q68D91 4.945177e-01
Q96D53 -6.69384693 Q96D53 4.945177e-01
Q9GZP0 -6.69384718 Q9GZP0 4.945177e-01
Q9UBX3 -6.69386800 Q9UBX3 4.945916e-01
Q6Y288 -6.69388580 Q6Y288 4.946141e-01
Q58EX2 -6.69391048 Q58EX2 4.946141e-01
Q9P035 -6.69391067 Q9P035 4.946141e-01
Q92614 -6.69393105 Q92614 4.946949e-01
O75376 -6.69395546 O75376 4.948265e-01
O43615 -6.69399068 O43615 4.949840e-01
O43169 -6.69399391 O43169 4.949840e-01
Q6UW68 -6.69403286 Q6UW68 4.951918e-01
P35968 -6.69403495 P35968 4.951918e-01
Q9GZY4 -6.69404913 Q9GZY4 4.952231e-01
Q8IZQ5 -6.69407310 Q8IZQ5 4.953303e-01
O60841 -6.69408020 O60841 4.953303e-01
P28288 -6.69409240 P28288 4.953448e-01
O75417 -6.69415329 O75417 4.960466e-01
Q15067 -6.69417614 Q15067 4.962373e-01
P26368 -6.69421171 P26368 4.964556e-01
P23919 -6.69421245 P23919 4.964556e-01
Q155Q3 -6.69422554 Q155Q3 4.964556e-01
Q13232 -6.69422754 Q13232 4.964556e-01
Q6FI81 -6.69423719 Q6FI81 4.964684e-01
O00505 -6.69428425 O00505 4.971514e-01
Q15008 -6.69429821 Q15008 4.972680e-01
O00743 -6.69430938 O00743 4.973387e-01
Q32P44 -6.69435312 Q32P44 4.981205e-01
P78417 -6.69436435 P78417 4.982347e-01
P14621 -6.69437287 P14621 4.982936e-01
Q9BYD1 -6.69438001 Q9BYD1 4.983248e-01
P61586 -6.69439056 P61586 4.984529e-01
Q14566 -6.69439736 Q14566 4.984907e-01
P10915 -6.69440748 P10915 4.986324e-01
Q9BXS5 -6.69443460 Q9BXS5 4.993656e-01
Q6P1M0 -6.69444145 Q6P1M0 4.993836e-01
Q9C0D5 -6.69444293 Q9C0D5 4.993836e-01
Q15185 -6.69444902 Q15185 4.993849e-01
P51153 -6.69445018 P51153 4.993849e-01
P29144 -6.69445665 P29144 4.995269e-01
P09543 -6.69447856 P09543 5.007025e-01
Q9BZF1 -6.69448357 Q9BZF1 5.010516e-01
Q92538 -6.69448566 Q92538 5.011896e-01
Q96N64 -6.69448651 Q96N64 5.011896e-01
Q52LJ0 -6.69448746 Q52LJ0 5.011896e-01
P54753 -6.69448773 P54753 5.011896e-01sum(toptable_Dupcor$adj_q_values < 0.05 & toptable_Dupcor$logFC > 0 )[1] 103sum(toptable_Dupcor$adj_q_values < 0.05 & toptable_Dupcor$logFC < 0 )[1] 312toptable_Dupcor %>% head() logFC AveExpr t P.Value adj.P.Val B Protein
Q15327 -3.553817 23.99047 -16.74339 2.054348e-08 6.951913e-05 9.416789 Q15327
O76021 -2.141093 24.25375 -13.55227 1.444049e-07 2.443330e-04 7.859382 O76021
Q96LW7 -1.634296 19.97143 -12.65816 2.690260e-07 3.034614e-04 7.328583 Q96LW7
Q969Q1 -4.342380 20.84232 -11.92097 4.632261e-07 3.918893e-04 6.853153 Q969Q1
P19388 -1.165897 20.44496 -11.62228 5.822611e-07 3.940743e-04 6.649959 P19388
Q96GQ7 -1.762280 20.67219 -10.83369 1.092754e-06 6.163133e-04 6.081777 Q96GQ7
adj_q_values
Q15327 3.487221e-05
O76021 1.225624e-04
Q96LW7 1.522224e-04
Q969Q1 1.965796e-04
P19388 1.976757e-04
Q96GQ7 3.091553e-04PCA
vobj$weights [,1] [,2] [,3] [,4] [,5] [,6]
[1,] 17132.1099 17132.1099 17132.1099 17132.1099 17132.1099 17007.0547
[2,] 11033.8518 10961.4090 10835.0512 11198.3257 10794.2739 10750.8137
[3,] 15008.9347 15039.3094 14937.5893 15030.8428 15040.1900 14895.0077
[4,] 16337.7187 16379.6411 16283.2262 16342.1804 16400.7563 15851.1159
[5,] 4367.9891 4455.4185 4424.0042 4276.7542 4576.0995 3867.6563
[6,] 10815.7854 10824.7093 10742.1450 10853.1691 10801.2065 10620.9251
[7,] 3566.1134 3539.3208 3441.2668 3654.5682 3451.2333 3357.6596
[8,] 5038.0182 4816.0634 4622.1142 5446.4133 4414.3883 5356.7074
[9,] 1323.3593 1350.7543 1327.8961 1303.2119 1383.5313 1564.7979
[10,] 458.5167 468.5052 467.3963 447.1539 483.8557 443.6331
[11,] 12502.7795 12494.2119 12396.4525 12570.9762 12437.0803 12238.1900
[12,] 12202.9774 12229.7168 12148.2047 12217.5528 12234.1235 11930.6434
[13,] 481.6507 492.1425 490.9111 469.7156 508.2065 530.6410
[14,] 2273.9635 2469.0827 2506.1865 2030.9833 2803.6908 1931.8150
[15,] 11695.9699 11749.4159 11684.6887 11667.7185 11802.8085 11512.9559
[16,] 11880.2259 11903.2000 11821.9193 11899.3444 11901.9031 11698.5711
[17,] 11751.6584 11766.1613 11680.8433 11783.6934 11749.9955 11465.9153
[18,] 11071.8202 11049.1732 10948.3691 11159.1021 10969.0562 10960.3329
[19,] 10601.3048 10592.4246 10501.3560 10666.0146 10537.8267 10425.1036
[20,] 9729.4557 9745.4804 9669.2772 9754.2586 9735.7555 9700.5468
[21,] 11434.0781 11670.4032 11703.1576 11128.4715 12055.5455 12064.9536
[22,] 10776.1085 10884.8923 10854.3407 10659.8759 11040.3313 10484.2316
[23,] 12281.0878 12309.8270 12228.5805 12293.0251 12317.4403 12130.1287
[24,] 11057.8244 11040.0514 10941.7739 11137.4050 10968.5221 10928.8613
[25,] 10214.7381 10284.6659 10236.2836 10156.7125 10371.3069 9824.8353
[26,] 10532.4741 10684.3198 10677.2047 10350.4987 10915.9972 10338.5437
[27,] 10928.0369 10973.9883 10909.3209 10908.9922 11015.6299 10728.5333
[28,] 7178.2514 7201.1693 7145.7550 7182.2938 7211.4774 6950.7960
[29,] 11306.0185 11307.3090 11217.8818 11356.6149 11269.2866 11132.5867
[30,] 9955.7607 10029.7953 9983.9413 9891.3837 10124.0571 10437.2802
[31,] 10675.3390 10650.4922 10550.5312 10764.3651 10567.5826 10659.7942
[32,] 9210.7494 9240.7301 9170.1187 9214.9359 9255.0684 9004.2461
[33,] 10279.1337 10285.7257 10204.0758 10318.9017 10259.0511 10147.0894
[34,] 10982.8435 11009.1854 10933.9454 10994.2084 11015.7660 10823.9713
[35,] 10669.9914 10668.3974 10580.3497 10723.4530 10626.2968 10646.4946
[36,] 9599.5253 9644.3484 9584.3377 9579.1707 9686.5260 9454.8693
[37,] 9255.2428 9327.8523 9282.5437 9189.5370 9419.9580 9008.1797
[38,] 11788.8227 11812.4134 11731.4080 11807.0083 11812.2030 11524.0275
[39,] 9657.8533 9635.7073 9540.0687 9741.6137 9559.1971 9532.2043
[40,] 9950.4377 9977.7088 9907.7923 9957.5668 9988.1779 9738.0949
[41,] 10143.5924 10171.5887 10100.4546 10150.3406 10182.6462 9963.8626
[42,] 9309.5624 9336.5818 9267.2644 9316.6586 9346.9299 9232.7025
[43,] 9072.4280 9074.1949 8990.7821 9119.3190 9039.3124 8935.1198
[44,] 9861.2171 9839.6930 9742.7365 9942.9611 9762.6817 9698.1151
[45,] 10370.8458 10379.7910 10298.3969 10407.5226 10356.8444 10320.4579
[46,] 10162.5151 10158.0563 10069.6359 10218.6323 10111.3305 9985.2504
[47,] 10136.9867 10148.4737 10068.4961 10169.4239 10130.0682 10273.2205
[48,] 8592.5753 8574.2849 8480.3327 8669.9821 8504.0673 8470.5287
[49,] 9716.2206 9729.5273 9652.0766 9745.1453 9715.0564 9616.0456
[50,] 9436.1288 9423.7196 9332.8589 9505.2273 9363.8332 9262.1827
[51,] 9251.6618 9252.8815 9167.1053 9298.7155 9216.0955 9134.7570
[52,] 7622.6290 7621.8466 7547.9514 7667.1332 7587.3472 7404.6947
[53,] 10482.4387 10460.9375 10363.1760 10566.1440 10383.7205 10358.4434
[54,] 5275.2175 5546.4122 5600.3693 4913.7623 5976.5471 6095.8515
[55,] 9169.0699 9193.3869 9120.3619 9181.7001 9197.8765 9030.2074
[56,] 188.3453 194.7913 197.0207 179.5602 206.3156 316.4722
[57,] 9778.6404 9786.0997 9704.9824 9817.0252 9760.9896 9564.8080
[58,] 10378.3462 10388.5358 10307.7010 10413.1401 10367.7529 10241.4506
[59,] 9485.5573 9639.8567 9636.5389 9296.7948 9876.2270 9279.4603
[60,] 11087.8782 11096.5254 11012.4048 11126.5198 11071.8976 10805.2676
[61,] 10684.3497 10656.9397 10555.5827 10777.2074 10569.5118 10643.6525
[62,] 9381.6588 9389.2988 9309.2617 9419.1910 9364.9487 9190.5684
[63,] 553.4979 540.8150 526.8053 578.6969 515.9517 561.9916
[64,] 9458.7043 9463.1493 9380.6198 9501.7034 9432.7737 9701.0829
[65,] 9793.3704 9779.7916 9687.7866 9864.1548 9717.6075 9481.4268
[66,] 9226.8365 9235.4144 9153.6769 9263.9551 9211.7311 9262.3412
[67,] 11143.1252 11102.6080 10992.6575 11258.8515 10991.3255 11123.1088
[68,] 9228.0198 9076.2191 8912.5792 9509.0690 8770.0783 9325.5808
[69,] 11093.4425 11165.2319 11113.5842 11035.1048 11253.2295 11356.1468
[70,] 8767.5430 8758.6113 8669.5301 8831.2567 8704.8244 8711.9987
[71,] 9384.7204 9382.9302 9298.0490 9436.9249 9341.9466 9138.0158
[72,] 9462.0993 9489.2411 9418.2797 9470.0075 9499.0329 9259.2661
[73,] 9753.7354 9881.1693 9863.5194 9607.8863 10067.8266 10170.7162
[74,] 8958.3101 8979.7160 8905.8689 8973.9955 8980.1462 9069.9557
[75,] 614.9234 644.5137 650.1651 580.1144 701.7446 726.4213
[76,] 9980.0717 10010.0426 9941.2000 9983.2246 10025.1721 9619.3601
[77,] 9743.6448 9741.2480 9655.4785 9797.1192 9698.9395 9463.2808
[78,] 7495.2531 7463.2220 7376.1283 7588.5831 7375.3455 7361.5902
[79,] 5851.2196 5900.2460 5838.7526 5826.6475 5948.4676 5330.7277
[80,] 6774.9401 6855.0969 6831.6783 6684.8037 6969.9040 6690.4185
[81,] 8657.0143 8679.2143 8606.6410 8671.6198 8680.9412 8679.3780
[82,] 8813.8132 8863.5772 8803.9134 8787.1883 8913.6296 8752.8290
[83,] 9542.2387 9561.4167 9485.6296 9562.6589 9556.9423 9311.1672
[84,] 7996.4201 8010.4567 7938.4551 8021.2586 7999.5488 7930.3018
[85,] 9301.7378 9324.4331 9252.7181 9315.4511 9327.1380 9233.3102
[86,] 8757.0104 8781.4609 8709.5080 8768.8503 8786.6389 8318.6959
[87,] 8850.7421 8880.6788 8810.4004 8854.7920 8895.0985 8644.2808
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[991,] 1763.5278 1795.0394 1759.7233 1745.1853 1827.9963 1296.8253
[992,] 4252.7680 4231.8615 4144.6753 4331.4655 4160.8928 4276.4582
[993,] 3222.0541 3215.7887 3132.6579 3276.7299 3168.6476 3137.9937
[994,] 2413.9456 2374.8482 2289.5029 2512.1747 2278.6339 2254.3530
[995,] 4136.2939 4150.2174 4078.9034 4158.7506 4141.0797 3951.9979
[996,] 3668.8447 3690.6014 3621.4783 3682.5456 3692.7632 4016.5734
[997,] 3482.7630 3431.4213 3324.4638 3606.2118 3307.0989 4073.0166
[998,] 5142.8103 5195.4688 5133.1853 5114.2866 5249.1120 5836.7765
[999,] 5081.7101 5164.9469 5119.4882 5006.5529 5275.1557 4670.3698
[1000,] 2830.2129 2963.4165 2958.8825 2676.7339 3170.7505 3295.0068
[1001,] 4121.5513 4229.0914 4209.4352 3990.3852 4392.0914 3593.0543
[1002,] 5251.4089 5357.9254 5323.8579 5140.8067 5502.7627 5167.7992
[1003,] 4022.7093 3969.4390 3863.1322 4151.3445 3842.2521 3646.2808
[1004,] 3756.8913 3681.9215 3564.1275 3916.6065 3517.8759 3846.3561
[1005,] 3496.4618 3550.2891 3497.3262 3459.7172 3607.0944 3557.3291
[1006,] 3859.9538 3872.2165 3799.5643 3886.3852 3859.0800 3244.8576
[1007,] 4387.1410 4277.9802 4145.5937 4598.2641 4052.6304 4964.7656
[1008,] 4290.7169 4314.3038 4248.1780 4300.3155 4320.7129 4610.4086
[1009,] 4271.1991 4288.9533 4220.3708 4289.5310 4285.2088 4139.7975
[1010,] 4074.1147 4056.0422 3965.3485 4147.2438 3987.7419 4038.9908
[1011,] 2708.3034 2697.6804 2620.3225 2765.8037 2645.9305 3497.3923
[1012,] 3174.9602 3201.7791 3136.0756 3180.3638 3213.3639 3333.3391
[1013,] 4537.5125 4538.8247 4461.4746 4581.7471 4505.8746 4637.1081
[1014,] 4063.0357 3971.2628 3845.8014 4244.3124 3776.1815 3550.1802
[1015,] 4096.6403 4075.8149 3983.2247 4171.4305 4002.5393 3656.4930
[1016,] 5232.9905 5218.4098 5120.7283 5309.6218 5152.1628 5473.8513
[1017,] 4490.1449 4499.1920 4426.6870 4521.7168 4480.2712 4470.3414
[1018,] 2971.6129 2968.0366 2890.7172 3020.5568 2927.7428 3072.8115
[1019,] 4576.5621 4543.1650 4447.9486 4676.2245 4449.9234 4938.5863
[1020,] 3118.0183 3068.5584 2968.2785 3243.1064 2950.0803 2718.7599
[1021,] 3661.8625 3656.4394 3574.2532 3717.8270 3611.0207 3980.2629
[1022,] 3407.1669 3254.6371 3095.2823 3694.8861 2956.1461 3687.6703
[1023,] 3201.8235 3056.1214 2907.6089 3478.4312 2778.0303 3137.5242
[1024,] 2480.1310 2344.5675 2213.0344 2739.1433 2091.0712 2109.9066
[1025,] 3580.8507 3560.7468 3468.0216 3658.8179 3487.2635 3798.4055
[1026,] 5235.3708 5263.9654 5187.6115 5244.7502 5273.4840 5438.4015
[1027,] 4025.0293 4106.0355 4065.7312 3949.9644 4204.3132 4010.5044
[1028,] 2826.6791 2854.3002 2795.9335 2826.7694 2870.5309 2321.2031
[1029,] 2652.4662 2580.3186 2476.0353 2805.0824 2428.7504 2411.9441
[1030,] 1961.5388 2029.7877 2008.6896 1889.7470 2129.1762 1830.1226
[1031,] 3505.8386 3446.6523 3335.3541 3639.0341 3309.1185 3182.9647
[1032,] 3959.7729 3977.3019 3906.8600 3979.5199 3972.3381 4099.0566
[1033,] 3345.8875 3342.7248 3262.6368 3397.7882 3301.6608 3011.3802
[1034,] 3046.0845 3071.2987 3008.7886 3051.5978 3081.8514 3205.3052
[1035,] 4195.1053 4290.7370 4263.2459 4093.2541 4428.2165 3762.4226
[1036,] 3503.1255 3557.1070 3505.1217 3465.1660 3615.2820 3243.4702
[1037,] 2153.5956 2182.0827 2134.8658 2146.1063 2204.4743 2837.6330
[1038,] 3623.5759 3617.5401 3536.0924 3679.8869 3571.5302 3426.5456
[1039,] 4776.9093 4866.6377 4829.0641 4689.6576 4991.2176 4578.2241
[1040,] 3153.7327 3256.8107 3232.4505 3043.7756 3403.3934 2695.7598
[1041,] 2597.7271 2582.1458 2505.7100 2663.8938 2524.1233 3019.9530
[1042,] 4725.7107 4702.0510 4608.3960 4811.4608 4623.8558 4372.5474
[1043,] 6035.8999 6063.4811 6000.6504 6038.5386 6077.6269 6187.3643
[1044,] 4238.3703 4272.2565 4212.4547 4231.4856 4297.6162 4011.1054
[1045,] 3519.9189 3539.0722 3466.5501 3537.0314 3537.2101 3200.0714
[1046,] 4013.5561 4175.7935 4181.2685 3810.7062 4423.4736 3772.7749
[1047,] 3720.5288 3677.2761 3575.3785 3836.3560 3566.7962 3723.1613
[1048,] 3351.4177 3330.5298 3241.7956 3431.6057 3258.9789 3313.3487
[1049,] 2544.2304 2527.2760 2451.9586 2611.5434 2467.7322 2841.5500
[1050,] 2468.9167 2541.5051 2512.3175 2396.2421 2644.4827 2604.0653
[1051,] 4355.9232 4320.4227 4223.8144 4455.3853 4223.4859 4231.3738
[1052,] 2832.6424 2964.7562 2959.6411 2680.8534 3170.0846 2118.4171
[1053,] 2726.3400 2711.0314 2631.6162 2791.6687 2651.3864 2536.1634
[1054,] 3661.7575 3644.0629 3555.9595 3737.1838 3577.5240 3537.1531
[1055,] 4937.5929 4928.3351 4837.5872 5003.1791 4873.2670 4157.8520
[1056,] 5753.8396 5800.3715 5739.4078 5732.0228 5844.9304 5524.5533
[1057,] 1169.2080 1110.6267 1052.5811 1288.4474 1004.7976 1117.4015
[1058,] 3909.6134 3889.5067 3799.8571 3987.6973 3819.4691 3837.3920
[1059,] 1968.3276 1907.7540 1822.9034 2096.8188 1782.6072 1890.9850
[1060,] 7038.0547 7113.9525 7087.5108 6959.1462 7220.5234 6802.7420
[1061,] 2296.2185 2317.7554 2265.0076 2300.5733 2327.0526 2916.4148
[1062,] 2236.6020 2082.2386 1948.2898 2530.3113 1806.5017 2688.5630
[1063,] 2588.1460 2561.4402 2480.1093 2672.1185 2484.8320 2821.3234
[1064,] 3054.8047 3053.3519 2977.6719 3101.9225 3016.8636 4473.5739
[1065,] 3183.6719 3179.2296 3098.1572 3237.5267 3135.7726 3629.6434
[1066,] 3335.3772 3294.2236 3193.8621 3448.1122 3185.7775 5064.5260
[1067,] 2847.9272 2823.7605 2739.9104 2929.8154 2749.6596 2907.4077
[1068,] 2305.2172 2271.4296 2192.1135 2397.7763 2185.2296 2524.6310
[1069,] 3612.4323 3654.2335 3596.5435 3594.6202 3693.0568 3928.7797
[1070,] 1355.8195 1346.5130 1304.8825 1392.9917 1313.7040 1183.0453
[1071,] 4967.3508 4821.1810 4664.1780 5252.5680 4538.6078 4880.7347
[1072,] 2881.8721 2857.6301 2772.6702 2963.9136 2782.9093 2615.7206
[1073,] 4862.5023 4735.9272 4589.9542 5116.4518 4485.3345 5046.3885
[1074,] 3931.6675 3935.2077 3858.5914 3972.7477 3905.9520 4708.9798
[1075,] 2491.6977 2570.7205 2544.0236 2411.1116 2685.6575 2321.1274
[1076,] 3525.5944 3583.0967 3535.5214 3478.5714 3651.4308 3661.1786
[1077,] 2637.7247 2654.4287 2592.0437 2653.8362 2651.7761 2649.1419
[1078,] 3630.5922 3587.1931 3483.4786 3746.9777 3472.3675 3530.8889
[1079,] 4133.9329 4179.7439 4128.2855 4106.7559 4227.7197 3796.8530
[1080,] 2518.5783 2580.6973 2544.5863 2464.2106 2662.9136 3081.1883
[1081,] 3999.1795 3912.3635 3787.5256 4179.5608 3720.6415 3537.9121
[1082,] 1237.6897 1085.6320 989.9447 1545.9128 867.6647 830.4015
[1083,] 5166.9025 5210.5460 5143.2067 5152.3772 5247.6786 4947.4624
[1084,] 3368.5769 3316.0030 3210.3901 3500.6635 3188.3785 2669.4938
[1085,] 5758.3288 5777.1546 5702.1330 5779.0619 5772.1898 5717.3623
[1086,] 3444.8028 3483.8072 3421.3414 3433.2237 3516.0137 3195.8886
[1087,] 4154.2723 4194.4948 4139.7686 4136.6323 4232.1421 4129.3806
[1088,] 2973.1221 3039.5209 2999.6369 2913.5871 3126.4958 2912.3532
[1089,] 1718.7070 1699.2149 1640.6130 1779.7158 1643.7125 1427.6852
[1090,] 4535.2786 4750.3041 4783.5532 4259.2120 5118.3180 5934.8562
[1091,] 1979.2717 1993.6855 1944.1800 1989.6651 1994.0996 2428.9625
[1092,] 6683.3279 6659.9907 6579.7930 6760.1688 6588.3735 7071.5276
[1093,] 3432.5624 3583.7327 3582.0438 3250.5948 3816.1913 3739.5715
[1094,] 4268.0658 4254.0701 4169.9139 4336.0046 4194.8393 3851.9479
[1095,] 2836.7508 2801.9454 2713.4635 2935.7468 2710.2156 2619.4202
[1096,] 3608.0675 3471.2371 3317.4036 3868.4096 3193.9299 4447.1208
[1097,] 2544.6910 2557.1647 2495.8296 2565.5075 2548.4515 2534.1565
[1098,] 2293.4451 2311.3051 2256.8777 2303.3859 2314.0893 2456.6241
[1099,] 3681.5091 3691.8515 3616.7957 3713.0900 3673.6903 3758.4490
[1100,] 4432.4050 4380.4721 4273.0325 4558.1233 4251.1204 3982.3932
[1101,] 4552.2635 4558.1824 4482.7953 4589.4961 4533.1609 4414.7014
[1102,] 3335.0142 3313.6131 3224.6063 3415.7387 3241.4087 3621.4699
[1103,] 4773.3930 4843.7489 4796.3699 4714.8572 4932.5150 4465.1207
[1104,] 3112.5671 3053.4456 2948.6493 3252.9473 2917.6174 3042.3530
[1105,] 3778.0353 3830.6005 3775.4036 3744.9327 3882.9924 3607.9481
[1106,] 4928.3731 4927.8403 4841.5910 4980.2476 4888.0527 4631.3892
[1107,] 3134.0938 3019.7332 2886.0516 3362.0948 2790.4078 3945.5129
[1108,] 3222.4888 3241.7588 3171.8888 3238.9003 3240.4944 3823.8773
[1109,] 2725.1394 2712.9186 2635.2400 2785.5054 2659.0561 2484.5422
[1110,] 3750.1172 3751.9806 3670.9305 3796.0581 3718.1336 3655.0850
[1111,] 4135.3465 4184.5632 4134.7885 4102.5850 4238.7110 4822.0308
[1112,] 3438.2446 3444.4533 3366.1736 3477.0582 3418.4648 3623.2752
[1113,] 3114.3172 3070.0271 2972.2671 3231.5549 2960.2465 2960.1982
[1114,] 3398.2609 3402.0465 3323.7726 3440.1617 3372.3612 3817.5791
[1115,] 1818.7180 1779.8029 1708.2979 1913.3995 1689.3197 1957.9762
[1116,] 3335.2929 3279.1038 3170.1821 3472.8033 3143.1161 3601.1611
[1117,] 2543.8864 2587.8863 2541.9333 2516.7201 2635.9482 2574.3179
[1118,] 4639.5128 4669.0434 4603.5277 4641.3566 4684.9766 4609.8103
[1119,] 2534.8828 2572.9053 2524.3114 2516.4959 2610.1617 2342.9756
[1120,] 3802.2874 3730.3356 3612.7108 3953.4032 3571.4808 4406.9483
[1121,] 3619.5302 3603.8321 3516.8365 3691.0926 3541.2313 3624.3209
[1122,] 4246.5174 4199.2773 4097.6631 4367.4407 4079.9063 4071.4595
[1123,] 2582.8815 2519.3111 2420.4271 2725.3995 2379.4499 2629.4700
[1124,] 3982.4477 3985.5633 3907.4749 4024.9467 3954.9925 4320.0191
[1125,] 3429.5293 3426.1313 3343.4757 3483.2750 3383.5466 3256.3921
[1126,] 3106.4805 3199.4493 3168.8306 3012.6407 3327.8548 2829.0699
[1127,] 3231.7879 3591.6322 3701.1333 2750.9053 4194.0671 3365.9554
[1128,] 4727.2841 4770.0956 4709.7965 4709.6890 4809.1947 4720.6703
[1129,] 3455.7698 3347.8474 3214.5107 3667.7877 3126.5121 3202.3022
[1130,] 2996.0029 3041.3469 2990.2667 2970.0956 3089.0007 3329.3910
[1131,] 3870.6220 3876.2903 3800.1972 3907.4743 3851.4457 3762.2875
[1132,] 3769.1615 3912.3643 3907.9142 3591.9334 4132.7835 3722.4014
[1133,] 3272.0490 3206.7468 3093.0077 3420.9054 3055.7428 3176.7564
[1134,] 6091.7968 6063.4338 5970.4818 6182.2333 5979.0476 6223.6410
[1135,] 4425.8972 4396.2705 4299.9779 4517.2712 4305.4130 4732.6655
[1136,] 3996.9426 4052.6387 4000.2591 3959.0978 4115.7043 3861.5816
[1137,] 2562.9116 2756.7491 2788.6254 2317.8273 3085.5460 2640.2359
[1138,] 2010.7790 2006.5794 1947.2629 2050.9483 1973.8348 4600.1509
[1139,] 3169.4548 3146.7997 3057.5044 3251.1434 3072.4032 2952.4898
[1140,] 3820.9864 3709.8676 3573.6175 4029.9628 3483.9686 4366.7193
[1141,] 4263.3728 4222.4966 4125.3800 4374.2173 4117.4257 4357.1473
[1142,] 3675.9179 3648.3475 3555.1257 3767.3888 3564.8145 3673.6883
[1143,] 1258.7841 1314.9206 1308.1976 1196.5369 1402.1093 1455.1633
[1144,] 3186.5055 3397.8522 3430.9409 2915.8541 3745.1344 3794.9247
[1145,] 3446.3788 3481.8836 3417.6487 3440.1447 3507.7578 3134.5923
[1146,] 2813.9902 2811.8384 2739.4970 2860.0524 2775.7961 2991.4466
[1147,] 3157.8582 3132.3405 3042.0499 3244.4235 3053.2703 3394.9125
[1148,] 2583.4423 2576.1410 2504.0859 2636.0905 2532.4596 2769.6446
[1149,] 1871.3548 1884.6680 1837.3169 1882.8082 1883.6209 3130.4128
[1150,] 3125.4581 3101.3544 3012.7275 3209.9932 3025.1277 2983.6748
[1151,] 3127.3087 3099.6418 3009.2765 3217.6359 3017.3817 3041.0954
[1152,] 3693.6757 3763.9702 3718.3124 3634.4982 3850.6413 3541.7098
[1153,] 4374.4694 4494.1898 4479.5561 4232.5007 4676.6993 3937.7858
[1154,] 3141.9537 3240.6609 3212.7252 3039.6482 3377.5618 3069.4468
[1155,] 3121.9995 3115.5239 3035.3793 3178.2920 3069.4217 3220.3267
[1156,] 3872.0086 3929.4276 3881.0483 3829.7989 3997.3584 4111.4498
[1157,] 2467.6391 2496.6436 2445.8591 2461.5798 2518.5831 3196.1657
[1158,] 4599.2622 4594.2323 4512.4256 4654.2239 4549.6163 4611.7151
[1159,] 1216.9879 1197.9625 1155.5462 1267.8414 1150.6772 5130.6120
[1160,] 2320.4397 2374.4036 2336.7086 2276.7009 2442.0841 2533.7542
[1161,] 3285.3675 3295.2700 3222.6262 3315.7347 3277.7907 3087.0028
[1162,] 3225.1687 3264.8953 3207.3750 3208.3579 3300.5804 2974.8727
[1163,] 2862.5958 2952.6396 2924.2182 2771.1959 3077.5375 2972.0839
[1164,] 3194.5484 3127.4963 3016.7313 3343.1864 2979.4131 3166.8696
[1165,] 2685.0059 2638.8559 2545.3120 2794.9672 2528.6546 3351.5449
[1166,] 2015.4496 2009.0783 1948.6427 2059.1711 1972.4693 1892.9150
[1167,] 4872.7569 4875.2205 4791.6596 4919.2249 4841.2181 5053.0836
[1168,] 1106.8897 1078.6082 1036.3994 1171.2344 1019.3931 943.7902
[1169,] 3583.6363 3454.4266 3305.9804 3831.5751 3193.0856 3225.7627
[1170,] 2676.3987 2705.9807 2650.6550 2671.3662 2726.7847 2737.7515
[1171,] 3412.0427 3520.1785 3493.4280 3298.2930 3666.8450 4297.1617
[1172,] 3957.3872 4006.5935 3951.9531 3928.7345 4058.5036 3870.6981
[1173,] 3614.9502 3611.1790 3531.0608 3667.5508 3569.1972 3229.7934
[1174,] 2208.2217 2171.2157 2090.9231 2302.4073 2079.5891 2220.6643
[1175,] 2563.9894 2509.6304 2415.2377 2692.8592 2385.1356 2309.7532
[1176,] 4050.0572 4187.6188 4181.4263 3880.7696 4395.7966 4017.0121
[1177,] 2293.8474 2322.1660 2272.7884 2287.8210 2343.6901 1864.0844
[1178,] 2772.3853 2908.8120 2907.3371 2610.2101 3124.9356 2899.6614
[1179,] 2643.4988 2662.4860 2601.0100 2656.2029 2663.7940 2485.7182
[1180,] 4002.7381 4008.2401 3930.8141 4041.8101 3981.6147 3990.9546
[1181,] 1067.1347 1065.5089 1036.9472 1086.7766 1050.1492 1040.8254
[1182,] 3170.2739 3204.5675 3142.6637 3164.1819 3229.6303 3032.7393
[1183,] 2908.9684 2841.5046 2735.6670 3057.9004 2695.4817 3050.9972
[1184,] 4835.2286 4873.5529 4808.6581 4825.8347 4903.4938 4668.7777
[1185,] 3401.3393 3412.9879 3338.4301 3431.0199 3397.0301 3286.8468
[1186,] 3612.1465 3651.2100 3592.1689 3598.4789 3685.0848 3483.0860
[1187,] 4173.3998 4125.7625 4016.7788 4294.0067 3997.5565 4455.1102
[1188,] 3469.6811 3430.9626 3330.3146 3575.5591 3327.7720 3507.4690
[1189,] 2640.6085 2687.3265 2639.6125 2611.0977 2735.5252 2287.8979
[1190,] 2811.8836 2610.3784 2441.1964 3189.0650 2244.9305 2937.4307
[1191,] 2690.5514 2705.7000 2642.7150 2707.2573 2701.6853 2771.5209
[1192,] 4527.0862 4584.0916 4534.8306 4485.7934 4650.7566 4494.1426
[1193,] 2230.7057 2219.4408 2151.3595 2285.0818 2171.4695 2160.7094
[1194,] 2482.0708 2492.5562 2432.2758 2504.7418 2481.2836 3014.9464
[1195,] 3416.0447 3414.4260 3333.0233 3466.7477 3375.1045 3556.7240
[1196,] 2132.0640 2076.8123 1991.2337 2256.2020 1957.2381 2087.8203
[1197,] 3392.2178 3692.5406 3771.4189 2989.4532 4184.8400 3872.2953
[1198,] 2933.8371 2937.6225 2864.3183 2971.8026 2910.1597 2661.2929
[1199,] 2304.7860 2296.3427 2228.9932 2356.1727 2253.0875 2257.8525
[1200,] 3036.3788 3063.2763 3001.8860 3039.1387 3076.9762 2840.3480
[1201,] 3222.5029 3209.1705 3122.6578 3287.6376 3149.8893 2642.5477
[1202,] 808.8761 875.2388 891.8165 731.4400 1004.9924 983.5957
[1203,] 3580.0191 3501.2683 3375.9280 3750.0638 3321.7300 3956.4875
[1204,] 4093.6359 4049.2784 3945.4493 4202.2995 3936.1532 4564.4966
[1205,] 2100.8074 2073.7372 2002.0697 2179.8252 2001.1737 1624.9974
[1206,] 3427.4300 3385.9622 3285.2632 3540.8114 3278.7643 3551.2887
[1207,] 2540.2472 2596.0298 2556.0334 2495.5575 2665.9895 2436.6416
[1208,] 2181.5157 2151.9971 2076.3718 2263.0539 2074.0706 2213.3601
[1209,] 4368.4863 4402.0719 4339.4243 4363.5249 4424.2732 4080.9394
[1210,] 398.9045 418.0655 423.1083 374.6600 452.9235 641.9207
[1211,] 4137.3603 4148.5856 4075.5419 4164.0153 4134.6756 3669.8780
[1212,] 801.2676 794.3046 773.3611 823.2239 774.4083 897.2671
[1213,] 4227.3697 4203.0509 4114.7741 4311.1619 4126.4949 4560.7919
[1214,] 2665.7124 2750.5751 2725.1473 2574.5373 2873.3179 3029.2304
[1215,] 4065.6553 4073.2288 3995.2441 4102.4344 4049.5205 4212.4397
[1216,] 2035.2053 1966.7887 1874.5977 2182.3800 1823.5562 2005.2298
[1217,] 3908.4570 3923.4102 3852.9766 3931.4316 3914.4740 3954.4149
[1218,] 1901.3825 1848.4711 1769.2252 2019.4449 1735.4543 1849.2250
[1219,] 2657.0039 2699.9339 2651.1458 2632.1216 2742.9195 2534.5862
[1220,] 2243.4433 2246.0835 2185.6427 2276.0193 2222.8833 2431.1741
[1221,] 1890.2490 1876.5782 1815.8117 1944.7200 1828.5739 2400.5102
[1222,] 3456.8354 3529.7510 3484.2073 3394.3844 3615.3000 3141.6505
[1223,] 1751.3631 1798.3526 1771.2448 1709.8841 1859.8336 1598.3675
[1224,] 1041.8816 947.6832 881.9962 1237.5065 803.1149 781.3622
[1225,] 3632.2313 3722.1499 3688.1243 3543.3672 3846.9029 3638.8138
[1226,] 2144.5514 2152.8212 2096.1954 2167.9220 2139.7563 2729.7391
[1227,] 3984.4101 3954.8083 3860.7859 4078.7923 3867.8467 3745.2062
[1228,] 4028.6795 3975.6112 3869.2514 4156.4293 3848.6900 4064.4118
[1229,] 4461.3351 4471.3964 4400.0110 4490.9647 4454.5405 4464.6923
[1230,] 1820.1635 1939.5318 1947.8056 1678.4087 2138.3010 2081.8218
[1231,] 3306.6599 3354.3533 3300.2651 3279.5988 3404.2641 3295.4195
[1232,] 3687.2270 3663.1430 3571.2838 3773.2819 3585.3899 3623.9863
[1233,] 2641.2162 2706.0702 2669.3430 2583.0195 2788.0321 2842.5576
[1234,] 1725.6439 1714.1186 1658.9605 1773.9110 1671.8483 1958.6881
[1235,] 2251.6708 2397.0296 2408.9723 2075.7170 2636.1221 2934.4646
[1236,] 4630.7618 4681.7020 4627.1304 4599.8993 4735.9817 4456.0737
[1237,] 2223.0045 2232.3848 2175.4082 2244.6261 2221.2810 2055.5311
[1238,] 2886.4075 3155.2887 3224.6516 2539.0296 3622.1316 2679.4501
[1239,] 2366.3910 2382.7587 2325.0996 2380.1273 2381.7375 2254.4687
[1240,] 2719.0177 2753.6205 2702.0795 2706.5053 2784.0319 2365.9512
[1241,] 2790.9443 2758.9716 2672.3503 2884.4499 2671.6743 1734.5451
[1242,] 3772.4911 3871.1699 3843.7082 3664.7936 4008.3595 3654.4629
[1243,] 5067.0784 5039.6535 4937.8099 5161.9544 4951.7951 5204.7884
[1244,] 4437.4821 4415.4223 4323.7828 4517.2883 4338.9779 4208.7076
[1245,] 2320.7572 2381.0164 2346.4445 2267.8336 2459.3908 2851.0214
[1246,] 3218.3432 3253.0992 3192.1036 3210.2036 3279.0836 2883.7500
[1247,] 2411.0004 2554.1261 2562.7691 2234.2279 2789.8320 2919.4293
[1248,] 4355.5843 4416.5441 4369.4889 4307.5050 4486.9119 4246.3988
[1249,] 2825.7378 2819.0334 2744.1491 2879.2271 2774.9693 2589.5603
[1250,] 4148.7543 4169.4567 4103.9914 4160.9028 4172.2010 3722.8992
[1251,] 3771.2019 3801.3733 3733.5976 3773.6286 3817.2522 3697.0535
[1252,] 2629.1735 2713.7479 2688.0513 2541.5802 2831.9357 2363.3299
[1253,] 2923.2160 2948.0872 2885.3024 2929.3301 2957.6983 3917.8918
[1254,] 2371.4423 2417.1726 2373.6268 2340.8447 2466.9808 1943.9055
[1255,] 3251.7050 3206.3647 3103.2025 3367.0872 3090.5918 3297.4738
[1256,] 1517.0083 1462.5173 1394.7732 1633.6122 1353.7900 4057.8462
[1257,] 1338.7480 1321.5080 1276.0588 1388.4848 1274.9597 1488.3077
[1258,] 3298.5425 3281.0347 3192.8856 3372.3925 3214.7955 3247.7096
[1259,] 2598.6203 2627.7700 2572.7181 2594.8833 2647.9448 2442.6262
[1260,] 3540.6451 3411.4611 3266.5268 3782.1553 3155.6376 3447.6094
[1261,] 1955.7917 1897.5226 1814.1462 2080.9009 1776.1498 2332.0909
[1262,] 2147.8961 2100.9784 2018.5981 2258.0510 1995.3386 1815.5629
[1263,] 2407.4363 2412.0999 2347.4228 2439.7845 2389.8604 3036.2890
[1264,] 1933.1387 1972.7006 1935.8510 1906.2290 2016.1642 1676.1325
[1265,] 2265.0906 2245.5881 2173.4407 2333.4468 2183.6935 3491.0875
[1266,] 3121.0914 3081.8714 2986.2716 3230.1219 2980.3880 3589.9004
[1267,] 3281.3066 3360.2877 3322.6157 3205.7931 3468.6405 3103.3202
[1268,] 1722.4552 1833.5246 1840.3102 1591.4479 2020.9677 1597.5071
[1269,] 2925.5724 2928.5294 2855.0919 2965.0491 2899.7442 3132.3181
[1270,] 4013.9488 4045.0338 3979.9421 4013.6455 4063.5804 3759.3235
[1271,] 2156.3440 2144.0346 2077.2767 2211.7748 2095.2957 2019.3854
[1272,] 3541.5647 3589.0844 3536.1633 3512.6130 3639.2044 3885.2359
[1273,] 2890.7217 2870.4200 2787.0351 2966.4337 2802.2219 2526.8350
[1274,] 4682.6490 4671.1024 4584.2917 4748.5784 4614.3576 5150.4265
[1275,] 2918.6695 2970.6291 2922.7477 2882.3190 3028.3390 3121.7513
[1276,] 2770.9254 2786.6570 2724.2763 2788.2352 2782.5176 2933.5077
[1277,] 3739.4190 3789.3503 3732.2362 3711.3385 3839.2324 3628.5136
[1278,] 2133.4372 2117.7669 2050.2440 2194.5592 2063.7126 2183.5003
[1279,] 415.1318 412.4268 405.7408 422.5840 405.3667 489.9537
[1280,] 3172.9162 3226.3367 3173.7783 3138.0563 3282.6114 3267.1381
[1281,] 3526.9406 3559.8123 3497.1172 3520.7813 3583.5650 3330.8845
[1282,] 3476.4929 3517.3334 3454.8312 3462.6786 3549.9735 3152.8571
[1283,] 4447.2318 4525.1058 4488.1880 4372.0247 4631.0084 4244.1559
[1284,] 1493.5774 1521.2636 1493.1138 1476.0649 1551.9141 1558.6147
[1285,] 2327.9517 2390.2923 2356.5083 2272.1418 2471.6545 2112.4328
[1286,] 2286.1087 2337.2361 2299.3276 2245.8730 2400.8016 2847.0017
[1287,] 4277.1240 4277.7383 4200.5481 4322.1921 4243.7841 4461.8573
[1288,] 3177.1085 3176.2173 3097.0480 3225.6006 3138.9969 2848.4963
[1289,] 3838.4440 3848.6208 3772.8297 3867.7986 3832.0533 4443.5127
[1290,] 2004.6076 1912.6861 1812.2093 2188.7371 1736.4496 1794.0950
[1291,] 1592.7091 1641.4442 1620.1823 1546.4609 1709.9164 2608.7388
[1292,] 3789.1882 3844.7896 3793.1790 3749.3342 3904.6166 4054.6643
[1293,] 3806.3867 3851.8441 3795.8870 3780.8512 3896.1244 3745.3800
[1294,] 2993.1489 3021.1487 2961.6217 2993.4433 3037.4362 2275.4088
[1295,] 2816.7315 2766.7532 2670.8547 2940.4295 2647.8450 3662.2296
[1296,] 2204.0933 2163.1102 2081.2455 2304.2350 2065.4117 2684.3695
[1297,] 2388.0942 2450.2566 2415.9801 2332.0271 2529.5259 2313.7111
[1298,] 2705.5217 2682.2660 2597.9532 2782.8531 2607.2889 2498.8852
[1299,] 3107.4975 3086.8752 3000.4460 3186.0964 3016.7929 3416.7730
[1300,] 3509.6033 3573.7299 3529.1019 3454.0051 3651.6427 3728.0063
[1301,] 3205.6554 3228.3148 3159.6330 3218.0103 3232.0465 3132.3693
[1302,] 2861.1587 2863.8801 2792.3784 2900.4480 2835.6154 2379.0202
[1303,] 2837.9077 2954.7948 2941.1304 2708.2051 3130.1041 2424.9342
[1304,] 3692.5735 3809.3753 3787.4554 3565.9190 3970.5515 3663.2191
[1305,] 3001.6667 2969.3433 2876.7679 3097.2665 2877.2095 2988.5755
[1306,] 3616.7936 3635.9499 3566.9619 3633.6681 3634.1432 2626.5451
[1307,] 1713.6941 1715.7116 1667.3389 1740.1338 1696.8281 2106.8148
[1308,] 2551.7327 2640.5548 2616.8087 2459.6045 2767.4719 3047.9758
[1309,] 2992.9914 3019.6584 2959.4844 2995.3201 3033.5603 3378.5474
[1310,] 3115.1316 3270.0568 3272.4904 2930.5108 3515.3052 3097.5596
[1311,] 3518.6149 3549.7068 3484.7609 3516.6831 3568.9193 3095.2710
[1312,] 1151.8595 1158.0488 1129.6655 1160.9718 1154.6559 1977.2606
[1313,] 2715.5569 2759.0016 2711.9265 2689.6798 2805.5816 2556.0148
[1314,] 3533.3674 3496.2622 3394.1615 3633.1598 3393.7794 3555.8582
[1315,] 3464.3727 3470.3169 3391.1382 3504.0618 3443.5158 3305.9782
[1316,] 2919.7723 2878.6312 2784.5685 3026.6451 2775.1825 2720.2283
[1317,] 3208.5976 3296.6716 3264.9323 3116.8924 3420.4219 3276.4171
[1318,] 3704.9147 3757.5019 3702.6582 3672.2980 3814.7549 3791.1038
[1319,] 1769.6887 1751.8644 1692.2014 1827.8088 1698.2931 1623.0532
[1320,] 1169.0971 1200.8637 1184.5000 1140.1486 1244.0467 1707.5320
[1321,] 4943.6435 4912.0988 4810.3089 5043.6681 4818.5935 5572.9010
[1322,] 1217.8344 1248.9049 1230.5042 1190.8549 1289.9170 1067.7425
[1323,] 2410.5296 2397.6856 2324.6320 2468.7723 2345.2764 2498.4037
[1324,] 2764.3028 2878.1762 2865.1945 2634.4523 3053.0639 2628.4842
[1325,] 2419.1722 2410.2695 2338.7680 2471.1294 2364.4386 2196.6251
[1326,] 2251.3670 2133.6260 2015.3790 2482.4032 1911.8131 2410.4118
[1327,] 2335.4346 2340.3348 2278.2551 2366.3598 2319.6382 2506.4092
[1328,] 3114.1687 3140.5258 3076.4779 3119.1687 3152.1536 2515.5664
[1329,] 2949.4830 2989.8300 2936.8024 2929.4931 3028.7420 2699.8124
[1330,] 2934.1849 2892.7215 2798.0505 3041.0479 2788.5258 3062.1396
[1331,] 3011.4655 3065.0377 3017.5632 2973.5381 3127.5773 2518.6869
[1332,] 3238.7181 3285.0577 3232.2880 3211.1609 3333.4457 3259.5852
[1333,] 2387.8803 2454.2120 2422.4243 2325.3920 2541.3503 2256.7211
[1334,] 5580.4169 5610.8343 5534.4988 5587.5071 5623.1993 5279.3207
[1335,] 4503.2546 4503.0195 4425.6385 4549.4726 4467.6964 4578.1604
[1336,] 2954.3814 2834.5369 2703.7549 3188.2597 2601.0086 3617.5113
[1337,] 2496.4429 2468.2819 2386.4285 2580.9898 2387.8690 2523.2809
[1338,] 2605.6705 2600.6022 2528.8702 2655.2161 2560.4235 2710.3722
[1339,] 2582.6167 2647.2723 2610.2798 2525.7190 2730.0150 2922.2654
[1340,] 3209.1078 3158.0100 3054.1647 3332.1600 3035.6491 3351.3458
[1341,] 1886.0355 2002.9769 2007.8824 1748.1765 2195.4706 2237.3393
[1342,] 3742.2304 3708.7705 3610.9388 3841.8940 3614.4545 4398.9137
[1343,] 3211.5354 3146.6764 3036.3948 3355.8525 3001.8749 3278.4978
[1344,] 3692.9879 3573.2872 3427.1719 3927.0415 3320.8941 3655.2328
[1345,] 2412.4001 2409.8261 2341.5439 2455.2246 2374.9639 3150.9373
[1346,] 2144.3761 2288.9044 2303.0639 1968.7788 2532.0172 4184.6759
[1347,] 439.6084 459.3310 463.7890 414.6023 494.1145 509.6991
[1348,] 3027.0485 3096.7213 3056.8114 2965.6303 3188.9947 2962.7148
[1349,] 3235.2854 3325.2590 3294.5297 3138.8229 3455.1952 3505.9051
[1350,] 2709.5146 2709.9472 2639.0388 2749.5295 2679.4356 3199.4713
[1351,] 2556.8509 2607.8639 2564.9444 2519.5078 2668.6692 2437.2890
[1352,] 4461.1021 4425.5128 4326.9741 4562.8201 4324.8106 4251.1258
[1353,] 2575.7852 2668.9667 2646.6258 2477.9092 2801.4086 2525.8361
[1354,] 2804.1841 2961.2678 2969.4576 2614.4001 3215.4262 2742.6568
[1355,] 3244.1346 3269.9333 3205.1027 3249.2278 3281.1552 2849.1771
[1356,] 2968.9257 3038.2356 2999.9434 2904.6014 3130.7404 2585.6729
[1357,] 2310.1876 2320.4126 2261.7431 2332.2807 2309.4338 2482.0683
[1358,] 2083.1730 2112.4146 2068.0527 2073.0927 2137.7676 1989.7494
[1359,] 5069.8599 5125.0405 5065.6032 5036.6114 5183.9919 5099.2474
[1360,] 2043.4327 2039.7511 1980.9922 2083.4632 2007.5396 2146.8804
[1361,] 3131.9590 3138.1089 3063.7154 3168.5638 3113.7758 3454.6896
[1362,] 3194.7860 3135.8517 3028.8193 3330.7230 3000.9030 2813.2033
[1363,] 2926.5298 2998.0107 2961.4026 2859.3840 3092.7215 3248.9538
[1364,] 3171.3660 3255.6759 3221.0980 3088.6917 3368.2497 3076.2771
[1365,] 2810.0106 2937.3559 2929.8760 2664.2160 3133.6775 2579.0340
[1366,] 2129.7835 2234.5678 2227.8394 2010.0590 2400.1690 1907.7414
[1367,] 3937.5741 3768.7754 3597.1093 4242.6721 3427.7041 3943.2185
[1368,] 3146.1561 3176.5714 3113.5169 3145.5338 3195.0089 2903.5208
[1369,] 3397.5537 3266.9667 3119.0863 3650.5874 3004.3231 2716.9180
[1370,] 2999.6606 2985.2270 2902.4634 3066.3641 2925.7957 2674.0314
[1371,] 2523.0245 2500.4238 2422.5000 2599.0420 2431.5861 3509.8396
[1372,] 2934.8110 2899.5031 2807.6782 3032.0813 2805.4923 3020.2244
[1373,] 1058.3288 1116.9349 1118.2716 991.8344 1216.0564 1117.4691
[1374,] 3226.9643 3308.1468 3273.0095 3144.3117 3420.8178 3019.9208
[1375,] 2149.8527 2139.8361 2074.3797 2201.9267 2095.0963 2164.1963
[1376,] 3547.0800 3564.4520 3493.2170 3565.5934 3560.3440 3668.6165
[1377,] 2941.5859 2997.2944 2952.7311 2897.9094 3063.7658 3324.4700
[1378,] 2926.6869 3032.5218 3013.4045 2807.7491 3193.2611 2834.3669
[1379,] 3181.5065 3299.9906 3283.7048 3045.9578 3479.6012 2810.4864
[1380,] 1886.4914 1878.9682 1821.2059 1931.0010 1841.4488 1793.2995
[1381,] 2244.4846 2188.4853 2097.4851 2372.6634 2063.0230 3105.1578
[1382,] 2738.7512 2677.7658 2573.7990 2878.6032 2536.6117 2860.9277
[1383,] 2047.6227 1958.1642 1856.0946 2230.2670 1782.2053 1989.3134
[1384,] 4262.5060 4269.9659 4196.4825 4296.6902 4248.1526 5426.5390
[1385,] 1292.6842 1251.0324 1195.8357 1381.1765 1166.5269 1341.1439
[1386,] 2653.7565 2642.9717 2566.9388 2711.5373 2592.2679 2747.7459
[1387,] 1718.7720 1721.4853 1673.2598 1744.2280 1703.7278 1856.0491
[1388,] 420.7605 414.1020 405.3896 434.7234 400.4176 426.7759
[1389,] 2778.3158 2753.3728 2670.3104 2860.1484 2678.4718 2825.6066
[1390,] 4935.8094 5064.2006 5044.3585 4791.7060 5258.0420 4824.2581
[1391,] 2138.1441 2092.7562 2011.4106 2246.0872 1989.7351 2917.8155
[1392,] 4045.7223 4013.0398 3916.0062 4142.4119 3920.1514 4080.2960
[1393,] 2577.8236 2550.2622 2468.8729 2662.9873 2472.3825 2229.5580
[1394,] 2897.2235 3035.1587 3032.8395 2733.4543 3255.8392 2328.5351
[1395,] 2474.4218 2496.1475 2441.5978 2479.5951 2504.9136 2907.0480
[1396,] 2492.4132 2475.9370 2400.5440 2557.9342 2416.9859 2285.2275
[1397,] 3665.2095 3616.8609 3512.6546 3790.2365 3495.5616 3269.2253
[1398,] 2342.3520 2290.1306 2201.2685 2464.4257 2172.8890 2108.7433
[1399,] 2348.2064 2355.9026 2294.7167 2375.0237 2339.8911 2328.1007
[1400,] 2936.6515 2931.5594 2853.9230 2987.7814 2888.6733 2840.6418
[1401,] 2518.6410 2499.5682 2423.5037 2588.8638 2436.8284 2214.3852
[1402,] 3856.7508 3951.9871 3923.2068 3751.7957 4090.6500 3048.0819
[1403,] 2192.8742 2294.4039 2285.2735 2074.6365 2456.0534 1730.9109
[1404,] 4868.8250 4936.9557 4886.3607 4814.7937 5020.1148 4767.4846
[1405,] 1442.3764 1446.1791 1407.8593 1460.2429 1434.7070 1827.1973
[1406,] 2519.1570 2570.8242 2529.4872 2480.1412 2633.4640 2502.1285
[1407,] 3163.9437 3100.3322 2992.0941 3308.7635 2958.2621 3371.7727
[1408,] 2366.4938 2430.1191 2395.6248 2309.5481 2510.5665 3284.3827
[1409,] 2252.3337 2230.9458 2157.6664 2323.4901 2165.2827 2610.9643
[1410,] 3614.3670 3575.6244 3473.6224 3722.9120 3468.4158 3510.4458
[1411,] 3122.9029 3088.3650 2994.9034 3224.3132 2994.6515 3071.3111
[1412,] 2463.9069 2431.8812 2347.0406 2554.0307 2343.0578 2746.4756
[1413,] 2357.1040 2357.0691 2291.8984 2396.2358 2327.4606 2284.5050
[1414,] 2345.5573 2335.1650 2265.5011 2400.9013 2287.9474 1934.1628
[1415,] 2015.8194 2019.0484 1963.8792 2044.3673 1999.2268 2013.8488
[1416,] 5135.0758 5176.9222 5109.3678 5122.8890 5211.1416 5683.1429
[1417,] 2359.9019 2375.3938 2317.5381 2374.8566 2372.9238 1995.3503
[1418,] 2442.9091 2473.8622 2424.2998 2433.4208 2499.7056 2788.5608
[1419,] 3733.0551 3642.7561 3517.5768 3918.0926 3447.6988 3675.9973
[1420,] 4257.5129 4297.1351 4239.7717 4242.1423 4332.6124 5035.0396
[1421,] 4024.2349 3864.4079 3696.5454 4313.9985 3541.3935 3971.4119
[1422,] 2159.5004 2052.9678 1942.3092 2370.0561 1850.3596 2775.7672
[1423,] 6510.4105 6473.3692 6381.4808 6602.6948 6375.8990 6314.3083
[1424,] 1930.6502 1895.9786 1824.1048 2018.3579 1812.5677 1845.0877
[1425,] 4114.5485 4080.5432 3981.1180 4206.4243 3984.5116 4517.5564
[1426,] 2241.2545 2165.4655 2065.8734 2401.9222 2009.5935 2294.0616
[1427,] 2957.2727 2937.6618 2852.3596 3030.2588 2869.2390 2645.6246
[1428,] 1932.6565 1926.2211 1867.3128 1976.4298 1889.8050 1675.5331
[1429,] 1948.7666 1957.9437 1905.8302 1968.2963 1948.3207 2194.2835
[1430,] 2609.4194 2738.6116 2735.9123 2457.2603 2942.9980 3115.8683
[1431,] 2541.8007 2551.3491 2488.7033 2567.1067 2537.5338 2805.1680
[1432,] 4182.2972 4173.4941 4091.3027 4240.8836 4124.1195 4914.9169
[1433,] 3081.2382 3030.2221 2929.1372 3209.0048 2907.5559 3218.2535
[1434,] 2150.4230 2164.4088 2110.3081 2165.0457 2161.3165 2451.7323
[1435,] 2629.4641 2557.4434 2453.9827 2783.0888 2405.0063 2896.1503
[1436,] 2697.9477 2686.9540 2609.0166 2755.8444 2633.9372 2499.6454
[1437,] 1313.1862 1282.8043 1231.7643 1383.4931 1215.0614 1500.6665
[1438,] 2155.2941 2188.9486 2144.1865 2140.0490 2219.9802 1978.8726
[1439,] 1686.9498 1705.8466 1666.5024 1686.6872 1717.2218 1567.8146
[1440,] 2647.1528 2742.6782 2722.6341 2541.4362 2884.0785 2463.1548
[1441,] 3008.9168 3019.6676 2951.1901 3036.0861 3005.1132 3038.2767
[1442,] 3133.5522 3200.0766 3155.2721 3078.5787 3281.3206 3187.4937
[1443,] 2638.9890 2638.2006 2567.3961 2682.4318 2604.9056 3863.3375
[1444,] 3121.6548 3053.3720 2943.8317 3275.9604 2901.8156 3599.3952
[1445,] 4699.4709 4802.2901 4773.1378 4591.5691 4952.2561 4419.3721
[1446,] 3521.7805 3462.7201 3351.0091 3653.4333 3325.1673 3458.4775
[1447,] 3752.5129 3846.0243 3814.7785 3656.0800 3969.9594 3366.3522
[1448,] 4559.3264 4611.5624 4559.1924 4525.6173 4669.2114 4879.4349
[1449,] 4280.5629 4135.2712 3973.2729 4555.8781 3831.0759 4649.2133
[1450,] 2734.9092 2782.2420 2736.4785 2703.5738 2835.6695 2942.3341
[1451,] 1487.6451 1481.8985 1437.8549 1521.5450 1453.2842 1341.3347
[1452,] 980.2266 1038.7275 1043.3897 913.1515 1141.8790 922.7145
[1453,] 2276.3870 2276.1451 2213.6436 2314.1767 2247.4355 1645.6556
[1454,] 2547.4984 2598.4230 2555.7722 2510.1106 2659.2177 2597.1958
[1455,] 1770.8413 1742.0983 1677.3804 1846.4696 1670.4863 2261.7775
[1456,] 5279.5446 5241.7799 5131.7576 5389.2399 5135.2668 4970.7356
[1457,] 3562.5388 3572.2476 3497.2286 3593.1863 3554.4351 3368.8430
[1458,] 2508.2754 2607.6875 2590.8432 2398.4403 2757.0449 2481.3325
[1459,] 2272.8365 2329.1228 2294.2395 2224.7920 2402.6011 2051.7157
[1460,] 3052.2036 3053.5413 2979.2806 3094.8824 3021.9326 2583.0656
[1461,] 1235.7371 1279.5572 1266.9445 1190.8053 1343.4577 1811.3463
[1462,] 2709.7984 2784.2119 2752.7981 2634.9290 2888.7605 2694.1448
[1463,] 1992.9343 2090.2040 2083.3057 1879.1237 2245.8714 1949.7451
[1464,] 3859.7517 3786.2900 3664.2273 4018.4071 3617.0466 3910.3241
[1465,] 2459.9812 2429.2891 2345.3300 2547.5771 2343.1689 2424.7550
[1466,] 1645.5026 1619.8195 1561.0209 1715.2187 1555.3715 1427.7784
[1467,] 1910.9879 1963.3462 1933.6354 1864.8903 2030.4685 1702.9215
[1468,] 3743.5929 3780.4242 3716.6930 3735.4089 3808.6039 3603.1301
[1469,] 1741.8852 1894.5343 1923.5021 1557.0781 2166.5370 2529.3307
[1470,] 3338.0335 3272.4699 3158.3565 3491.2229 3119.6937 3634.2379
[1471,] 1377.9552 1380.3119 1343.4283 1397.0400 1367.1689 1840.8657
[1472,] 2536.0337 2515.2876 2438.4596 2609.3035 2449.4654 2373.0517
[1473,] 3527.4878 3560.1880 3497.4344 3521.6268 3583.6634 3475.3733
[1474,] 3080.7908 3018.2397 2910.9071 3227.8137 2875.1930 3686.8062
[1475,] 2610.8615 2579.5560 2495.3328 2701.6798 2494.9373 3261.5273
[1476,] 1664.5997 1614.9977 1544.7533 1775.3432 1512.1004 1460.2252
[1477,] 1453.2023 1425.9139 1372.5436 1521.3548 1361.5266 755.9311
[1478,] 2552.0677 2616.7847 2580.8508 2494.5238 2702.1782 2921.4131
[1479,] 3665.5228 3735.9956 3691.2016 3605.6521 3826.1216 3712.1963
[1480,] 1803.7280 1893.6192 1886.9644 1701.2579 2036.6348 1866.3479
[1481,] 2241.5624 2174.7379 2079.0850 2387.2880 2032.6266 2831.8667
[1482,] 3385.4766 3363.3680 3273.0562 3468.2206 3289.2880 3429.6727
[1483,] 592.5745 556.7513 531.5273 665.2755 496.8992 501.5287
[1484,] 1890.4394 2002.6052 2004.9333 1759.1833 2185.3730 1533.8584
[1485,] 2118.7559 2319.4129 2364.8425 1867.4809 2676.8515 1647.1631
[1486,] 2101.6802 2017.5297 1917.3780 2275.1271 1849.0279 1946.4397
[1487,] 5275.9747 5257.4869 5156.9608 5357.2816 5184.0678 4988.3999
[1488,] 1382.3353 1471.2453 1478.1079 1276.8911 1624.6188 1708.6956
[1489,] 2109.7121 2107.5120 2047.1410 2148.7908 2076.8006 2148.0843
[1490,] 2193.6606 2226.0228 2181.3920 2178.9986 2256.3582 2216.3655
[1491,] 2419.7901 2392.4905 2312.3802 2499.5540 2315.6352 2316.1070
[1492,] 3281.6906 3244.9664 3145.1339 3386.2683 3141.8232 3039.8937
[1493,] 2278.9975 2322.8160 2281.5400 2249.4198 2372.9152 2196.0182
[1494,] 2093.8649 2078.8906 2013.0763 2153.0291 2026.6436 2201.1783
[1495,] 2080.1734 2182.0950 2174.4315 1965.4805 2340.5181 2098.2317
[1496,] 2115.3263 2036.3405 1938.9894 2279.5434 1876.5981 2425.5921
[1497,] 2256.7904 2397.4706 2406.7207 2087.4603 2627.0721 2298.7375
[1498,] 2787.4162 2831.2257 2782.0521 2762.2982 2877.3827 2576.3872
[1499,] 1529.0251 1496.4100 1438.5347 1607.9439 1422.4481 2121.6972
[1500,] 3061.4335 3024.9955 2931.4326 3164.8289 2927.7054 2584.8068
[1501,] 2498.2197 2385.3269 2262.2138 2721.3862 2165.3329 2647.0434
[1502,] 2282.6034 2198.2919 2092.7392 2459.6236 2025.9649 2478.3369
[1503,] 2406.0499 2338.2652 2240.2016 2550.1099 2196.2903 3571.6879
[1504,] 1934.5578 1914.1930 1848.7358 1999.6833 1854.2408 2362.3878
[1505,] 493.4049 483.1184 471.2693 513.9420 462.6368 707.0288
[1506,] 2553.6462 2612.5917 2573.7216 2504.5607 2688.0998 2252.4290
[1507,] 1639.3524 1626.6187 1573.9995 1687.7180 1583.7340 1464.1548
[1508,] 2307.3672 2360.8912 2323.4331 2264.0222 2428.5717 2228.6310
[1509,] 2168.1353 2164.3212 2101.1364 2210.3187 2129.8987 1937.7534
[1510,] 2474.5864 2461.4006 2387.3379 2534.4723 2407.7323 2390.9173
[1511,] 2121.2488 2119.9029 2059.5313 2159.2203 2090.4814 2443.9289
[1512,] 3545.5372 3477.0791 3359.3331 3693.9866 3320.6544 3476.6764
[1513,] 3797.7301 3832.3033 3767.9163 3791.8718 3855.4775 3257.1533
[1514,] 3484.8612 3544.6174 3494.0396 3439.9892 3610.4075 4190.1800
[1515,] 1444.6733 1397.1795 1335.0827 1546.7113 1301.2168 1589.3071
[1516,] 3022.3477 2991.2715 2899.8111 3116.2921 2902.1889 3140.7760
[1517,] 3396.8784 3063.3668 2822.1666 3971.2877 2491.0171 3783.1225
[1518,] 2869.9633 2970.3292 2948.3890 2762.6700 3115.7654 3043.3047
[1519,] 2272.5491 2238.5758 2158.8308 2364.7570 2151.1059 1967.4719
[1520,] 2236.7131 2370.9460 2377.4940 2075.0538 2590.1040 2006.7345
[1521,] 1456.2991 1433.7983 1382.4908 1516.6941 1377.0919 1632.5510
[1522,] 1850.2666 1858.4104 1809.3438 1869.2796 1848.5893 2518.6164
[1523,] 3581.8416 3594.9819 3523.6532 3607.4664 3582.9716 3682.4943
[1524,] 2079.3156 2005.4946 1910.3163 2235.8153 1853.2243 2007.8503
[1525,] 1505.2718 1501.0970 1457.2036 1537.0343 1474.8941 1649.6420
[1526,] 3149.6909 3120.7542 3029.1029 3241.8209 3036.0428 3192.5058
[1527,] 2228.1454 2229.1317 2167.6354 2263.0092 2203.2962 1856.6126
[1528,] 2717.9899 2703.0662 2623.5746 2782.5448 2643.6934 2477.9480
[1529,] 1026.1230 1057.8019 1046.9499 994.4114 1104.8081 1209.6981
[1530,] 2014.3080 1874.7578 1753.2708 2281.5068 1628.5288 2705.7708
[1531,] 1484.4274 1467.3696 1417.9189 1536.5470 1419.5087 2050.7676
[1532,] 1895.7941 1860.2284 1789.1974 1985.9643 1775.9231 2683.2679
[1533,] 897.3445 921.1986 911.4393 874.5035 954.8170 1055.4566
[1534,] 2942.0710 3007.1123 2967.2137 2883.8607 3090.9947 2591.0687
[1535,] 1676.2200 1678.3688 1631.3987 1701.6447 1660.3230 1871.5581
[1536,] 3207.7098 3138.8173 3026.8002 3358.5512 2987.5721 3203.4425
[1537,] 2620.1305 2732.2440 2720.6665 2492.0034 2903.4078 2686.7578
[1538,] 2284.5866 2180.9784 2066.7908 2493.0462 1979.5504 3321.2614
[1539,] 2346.2545 2308.1457 2225.5846 2445.9527 2214.6500 2685.5624
[1540,] 2794.2754 2779.0550 2701.1186 2860.7442 2720.8707 2296.4528
[1541,] 1735.5276 1785.1877 1759.4795 1690.3689 1851.2882 1647.3103
[1542,] 3716.9062 3667.8993 3563.3763 3841.5031 3547.8797 3725.3631
[1543,] 1384.8354 1362.7487 1314.2008 1443.4632 1308.2271 1254.6633
[1544,] 1351.3874 1327.3609 1278.4245 1412.6224 1269.3231 1347.3881
[1545,] 3223.2274 3251.0706 3186.3274 3225.9317 3265.1527 3284.4010
[1546,] 2311.4020 2294.3971 2222.8038 2376.6673 2236.5007 2266.8269
[1547,] 1678.3540 1654.8176 1595.7970 1745.2072 1593.3022 1424.7481
[1548,] 2480.4235 2428.0253 2332.7653 2604.3730 2304.0330 2483.5965
[1549,] 1603.0714 1593.4417 1543.5773 1645.6655 1556.4008 1379.3469
[1550,] 1671.5185 1626.0206 1557.3434 1775.2896 1529.3897 2359.3277
[1551,] 2727.6721 2679.2798 2581.8126 2846.3565 2559.8464 2932.6597
[1552,] 3847.9262 3925.3041 3887.6255 3770.8201 4030.4721 3763.8086
[1553,] 4039.2552 4022.0602 3932.6631 4114.5631 3955.6621 4271.9194
[1554,] 2003.5836 1968.7880 1893.5502 2092.7290 1881.6624 1863.1957
[1555,] 2642.5571 2641.1182 2569.8857 2687.0280 2606.6441 2922.1603
[1556,] 2675.3000 2704.0884 2648.2116 2671.6585 2723.3485 2346.4555
[1557,] 2960.6271 3179.0896 3219.6617 2683.0348 3550.3250 2499.2775
[1558,] 2733.6413 2783.0224 2738.3147 2699.2333 2840.2453 2655.9073
[1559,] 2050.6427 2063.8796 2012.9216 2064.3318 2061.0687 1879.8323
[1560,] 1610.4413 1611.4070 1566.2483 1636.3192 1592.3765 1463.9772
[1561,] 1824.5434 1699.0236 1590.1007 2069.4292 1481.2252 2106.2650
[1562,] 934.1164 870.7659 820.9243 1064.0186 766.6696 783.1092
[1563,] 2424.9167 2431.2481 2366.7589 2454.0675 2411.6419 2682.9302
[1564,] 1989.6674 2073.5968 2059.9148 1894.8104 2204.3854 1723.2607
[1565,] 1992.4268 1972.3217 1904.5013 2057.4204 1910.4996 1934.1122
[1566,] 4107.0667 4185.5520 4150.8650 4023.5889 4292.4711 4112.9434
[1567,] 3141.8524 3121.7245 3034.4746 3220.2899 3051.9990 3029.8375
[1568,] 3138.5689 3125.7694 3042.0998 3205.2179 3068.5776 2636.3916
[1569,] 1273.7801 1299.2119 1276.0567 1256.1679 1327.9087 1226.6065
[1570,] 3295.4197 3226.5640 3109.6478 3452.7913 3066.7726 3317.2493
[1571,] 2886.5123 2942.0953 2895.5817 2845.6521 3005.4975 2901.3925
[1572,] 2100.6735 2103.5795 2045.9428 2131.5094 2081.8515 2023.5141
[1573,] 1517.0816 1419.2384 1332.6640 1714.0896 1245.8982 2223.1427
[1574,] 2839.7170 2827.6072 2749.7118 2902.0738 2774.0749 3031.5796
[1575,] 2598.9588 2595.3447 2524.5251 2646.0664 2557.7718 2639.8582
[1576,] 3551.4287 3543.0218 3455.5467 3610.3223 3490.2592 3275.1733
[1577,] 2032.4510 1972.1238 1883.6610 2165.8896 1841.5934 1845.6737
[1578,] 1026.8664 1163.4156 1210.5290 872.2615 1444.7750 1344.1484
[1579,] 3183.1793 3239.9301 3189.4998 3142.7477 3302.2829 3204.3041
[1580,] 2430.0161 2482.4557 2444.3610 2385.7883 2547.6430 2308.2783
[1581,] 2204.3509 2158.9020 2074.9951 2311.6762 2053.9778 2590.4283
[1582,] 1038.8661 1015.7677 978.1171 1093.4224 965.1412 1016.9775
[1583,] 1710.9530 1689.6547 1630.4979 1774.8125 1631.2859 1674.1703
[1584,] 3063.2746 3081.7271 3015.3967 3079.5017 3080.0064 2881.0268
[1585,] 2056.1335 2103.6293 2069.1877 2018.3458 2163.1084 1903.0258
[1586,] 1490.1338 1496.1279 1457.5841 1505.5707 1487.7998 1785.6674
[1587,] 1654.9759 1581.4781 1501.1491 1807.3973 1442.6237 1677.8281
[1588,] 1464.1286 1459.1828 1416.0659 1496.2609 1432.2180 963.8290
[1589,] 1446.9912 1459.5855 1425.5345 1451.3350 1463.6192 1682.6298
[1590,] 465.7070 434.5594 413.8939 523.7443 384.3705 620.1565
[1591,] 2541.9011 2502.7896 2416.1807 2645.3433 2404.5924 2533.7066
[1592,] 3563.0723 3482.4651 3357.6758 3732.9707 3303.1795 3006.9496
[1593,] 2576.0194 2569.6800 2498.3259 2626.9910 2527.7613 2552.8027
[1594,] 2299.0216 2399.3011 2385.8101 2188.7759 2549.8539 2051.3218
[1595,] 2939.0912 3000.5936 2958.9327 2886.5529 3077.6252 3592.5262
[1596,] 2035.5825 1964.4565 1871.0574 2187.3403 1817.0662 2229.0732
[1597,] 2814.5895 2789.1373 2705.7348 2897.9299 2713.3574 2723.7843
[1598,] 2258.0123 2253.4712 2189.2883 2302.2260 2217.6306 2137.3446
[1599,] 2974.9018 2932.4555 2835.4276 3084.8903 2824.0105 2414.1058
[1600,] 2108.4044 2131.7436 2083.6286 2107.7943 2146.0160 1846.0078
[1601,] 2533.0702 2557.0966 2501.7298 2535.8649 2569.0828 3027.8317
[1602,] 2890.7609 2845.9755 2751.1428 3004.3564 2736.9615 2713.5909
[1603,] 1280.3720 1344.0873 1340.8707 1206.9549 1447.2531 1401.9150
[1604,] 1523.4506 1601.2904 1597.4944 1435.4210 1729.2146 1616.1840
[1605,] 3947.3769 3931.2111 3844.6018 4019.7489 3867.6209 3846.1669
[1606,] 2407.9418 2496.6268 2476.8263 2309.9787 2628.8878 2722.7355
[1607,] 2581.2133 2723.1388 2727.0707 2411.8459 2950.5532 2460.3512
[1608,] 1017.2856 1055.8765 1048.8466 975.6490 1116.8389 1267.7717
[1609,] 3024.3773 2965.8726 2859.5526 3163.6261 2827.8715 2810.8711
[1610,] 2951.3760 2910.5156 2815.5773 3056.6825 2807.0585 3063.0723
[1611,] 2604.4766 2553.4810 2460.3890 2726.0655 2436.6950 2449.9963
[1612,] 2066.4144 2091.7780 2046.1201 2061.8590 2110.3866 2354.3728
[1613,] 3545.2798 3193.9339 2941.0296 4134.4859 2588.1352 2327.6749
[1614,] 2726.5055 2821.7603 2800.4143 2621.2620 2965.5179 2750.1227
[1615,] 2063.2779 2084.3320 2036.6970 2065.2186 2095.2399 2417.7489
[1616,] 6845.3823 6836.3402 6766.1989 6898.0521 6790.9523 6719.7621
[1617,] 1881.1056 1952.9222 1934.1022 1806.7086 2056.8344 1658.1881
[1618,] 4223.0685 4228.4636 4154.8503 4259.9408 4203.4293 4332.1336
[1619,] 1333.5909 1346.5479 1316.2740 1335.3479 1352.8175 1997.7025
[1620,] 2269.9468 2261.9418 2195.9882 2319.9166 2219.9769 2322.5787
[1621,] 2284.4525 2185.1605 2072.8298 2485.8635 1990.0594 1998.3321
[1622,] 2892.2884 3021.8804 3015.2080 2740.8055 3226.9480 2616.2228
[1623,] 1578.7365 1621.6581 1597.9973 1540.5687 1679.3287 1842.0703
[1624,] 2695.9149 2668.9719 2583.6034 2777.6190 2589.1312 2520.2645
[1625,] 1437.7413 1433.8290 1391.9122 1467.6277 1408.9178 1428.1795
[1626,] 1352.8738 1375.8657 1349.8194 1339.8476 1400.0148 1187.6807
[1627,] 785.9449 768.3564 743.2536 825.2702 732.4446 845.7150
[1628,] 2015.4086 2039.3813 1994.8323 2011.9188 2056.3155 2212.8568
[1629,] 1397.4534 1432.0087 1410.1256 1368.2193 1476.4336 2426.9821
[1630,] 1488.2730 1645.9122 1687.2641 1298.9496 1949.4271 1115.6158
[1631,] 1498.2100 1546.7234 1528.7849 1450.4509 1616.6325 1440.2671
[1632,] 3364.4598 3187.0743 3017.6376 3692.3914 2849.3515 3052.9129
[1633,] 2018.6190 2023.6085 1969.4509 2044.4664 2006.8110 2047.1472
[1634,] 1940.6971 1955.7078 1906.6724 1951.0225 1956.5234 2137.0251
[1635,] 1627.4482 1731.9522 1738.2913 1505.7747 1909.2316 1748.1977
[1636,] 3023.4701 3002.4306 2916.5194 3101.2001 2931.7387 3108.7552
[1637,] 1742.1880 1764.2277 1724.4096 1738.3195 1780.2653 1386.6367
[1638,] 1969.4413 1953.1593 1888.3352 2027.2272 1899.4584 2051.0526
[1639,] 712.6944 914.4565 1034.9316 545.6452 1547.6244 771.8892
[1640,] 1877.5696 1842.8044 1772.6640 1966.4781 1759.7018 2096.0543
[1641,] 1878.3300 1875.5923 1820.3689 1915.0435 1846.4020 2130.3939
[1642,] 2057.6772 2102.3858 2066.5100 2024.0178 2156.6301 1804.3767
[1643,] 1012.9775 988.9408 952.2661 1067.9953 938.2730 879.6220
[1644,] 1537.0866 1543.2671 1503.1786 1553.2135 1534.5207 1464.6734
[1645,] 1978.6029 1846.7961 1730.0590 2230.2833 1614.2193 1963.0381
[1646,] 3117.8168 2968.4257 2816.4121 3405.6773 2681.8191 2553.7799
[1647,] 1670.3392 1718.5631 1694.2286 1626.2654 1784.3796 2070.4607
[1648,] 2717.0275 2686.4645 2597.9957 2806.8537 2597.7996 2518.2882
[1649,] 2132.9820 2082.5273 1999.0734 2249.2673 1971.2152 2206.7441
[1650,] 3221.1463 3228.4069 3151.7916 3256.0016 3204.7623 3378.9737
[1651,] 956.8319 931.7130 896.6276 1013.8741 879.6277 2100.6014
[1652,] 1480.4813 1430.6027 1365.9868 1588.0501 1329.6162 1434.8662
[1653,] 2701.8653 2739.8481 2690.5103 2683.7895 2776.6555 2775.1190
[1654,] 3567.7019 3649.1758 3612.6293 3486.2808 3761.8376 3868.3136
[1655,] 2965.0198 3036.7448 2999.7887 2896.7044 3133.8589 2982.1149
[1656,] 1705.0590 1713.5859 1668.6152 1721.1373 1706.2205 1709.7615
[1657,] 2113.6221 2043.4264 1950.5563 2263.0423 1898.1130 2402.2359
[1658,] 1890.5355 1867.4649 1802.3371 1960.3207 1803.7477 2343.0170
[1659,] 2558.2825 2607.9625 2564.3350 2522.9407 2666.2733 2491.1163
[1660,] 1715.8201 1709.8321 1657.6129 1754.9899 1677.1275 2332.5456
[1661,] 2425.9788 2529.3553 2517.1146 2304.8442 2692.1204 2185.0392
[1662,] 1573.3311 1568.8669 1522.4656 1606.9974 1541.0899 1369.5045
[1663,] 1119.0802 1234.5851 1264.9548 982.8635 1454.0965 736.7459
[1664,] 1794.7893 1761.4071 1693.4956 1878.9872 1681.1157 1765.1674
[1665,] 2166.2203 2150.3639 2081.6029 2226.8668 2095.4689 2267.9903
[1666,] 2911.0087 3021.4476 3004.7585 2786.2622 3189.9352 2877.0319
[1667,] 2150.8642 2119.2779 2043.7803 2236.4488 2038.4527 1923.4433
[1668,] 1524.7162 1475.4174 1409.8725 1632.3006 1374.7331 2062.9277
[1669,] 1757.9661 1753.0086 1699.7584 1795.9333 1721.3774 1334.6921
[1670,] 2037.8089 2076.5105 2038.3730 2012.6437 2119.9526 2225.3094
[1671,] 3568.6953 3635.4208 3591.3887 3511.3786 3720.5087 3468.3319
[1672,] 1000.1431 950.2105 903.3868 1103.1124 862.2136 908.0748
[1673,] 2538.6963 2414.3101 2283.5637 2782.2951 2173.0126 2699.6948
[1674,] 2726.6569 2767.4709 2718.7459 2704.9249 2809.0698 2607.8818
[1675,] 970.1658 967.5639 942.6007 989.0421 952.4585 1049.8084
[1676,] 1884.2874 1961.4174 1945.1878 1802.5294 2074.7846 1592.9110
[1677,] 1794.0914 1782.8855 1725.3961 1842.5263 1739.6657 1815.6578
[1678,] 2075.9129 2039.6676 1964.0208 2169.6184 1951.2086 2140.0946
[1679,] 2060.6410 2120.0575 2091.3964 2005.6036 2201.7026 1892.9478
[1680,] 953.0359 1030.6121 1046.9575 862.6922 1178.6764 1689.0224
[1681,] 476.0424 491.5506 493.0632 456.8366 517.2625 505.8460
[1682,] 1249.7573 1249.6545 1214.9884 1270.6828 1233.7769 1787.6668
[1683,] 2273.1860 2294.6671 2242.6832 2277.1581 2304.2309 2542.9060
[1684,] 2861.9460 2886.0522 2824.8515 2868.0754 2895.4731 2805.9785
[1685,] 1113.2870 1062.8342 1011.1897 1216.9709 970.7545 1465.1047
[1686,] 1439.5569 1395.7084 1335.4371 1535.1047 1305.5741 1770.3745
[1687,] 2400.1849 2405.6871 2341.6602 2431.5113 2385.0239 2597.0411
[1688,] 2039.8271 1952.4626 1851.7727 2218.5941 1780.3752 2489.3280
[1689,] 1780.3630 1808.5333 1771.4611 1767.0208 1835.7313 1641.1927
[1690,] 2643.2382 2557.3472 2447.2205 2818.5458 2381.6578 2555.6718
[1691,] 1659.4647 1717.8124 1698.9658 1600.7257 1802.8823 1453.4516
[1692,] 2509.5607 2540.0963 2488.6763 2501.9875 2564.1534 2474.2559
[1693,] 963.1042 1049.4862 1070.3250 862.9587 1217.5122 813.0820
[1694,] 2264.5273 2304.1853 2261.3612 2240.8575 2346.8551 2135.1966
[1695,] 2674.5401 2748.3812 2717.3945 2599.4981 2850.9686 4836.3450
[1696,] 1718.0875 1714.1370 1662.7928 1754.0601 1684.8831 1944.7277
[1697,] 1413.0208 1444.6309 1420.8332 1388.3099 1483.3483 1440.8865
[1698,] 1691.6401 1661.4520 1598.9148 1769.8258 1588.8449 1480.8015
[1699,] 1239.7652 1263.0772 1240.0679 1224.6253 1289.2208 1595.9603
[1700,] 996.3517 982.3408 950.8625 1034.1831 947.8223 943.9096
[1701,] 4039.8819 4023.3048 3934.1916 4114.2553 3957.9611 4182.1832
[1702,] 1890.0624 1898.1354 1847.6108 1910.0408 1887.5396 1604.5108
[1703,] 1877.3568 1900.7446 1858.0290 1873.5210 1917.6181 1983.3299
[1704,] 854.7055 891.0129 889.4309 813.2995 951.3824 2702.6752
[1705,] 3865.0144 3814.6171 3702.9176 3990.3668 3682.0864 3687.1997
[1706,] 1801.2563 1730.4252 1645.5825 1949.1276 1591.4316 1619.3850
[1707,] 3204.7638 3191.3454 3105.3404 3270.9022 3132.1667 3370.8403
[1708,] 5399.7083 5382.3396 5282.8326 5479.0686 5311.2667 5381.9440
[1709,] 2242.4689 2269.9580 2221.9411 2236.6678 2290.8107 2391.0920
[1710,] 1423.1195 1376.8536 1316.0805 1522.7517 1282.7594 1722.1274
[1711,] 1026.6631 1079.2173 1078.9284 966.5336 1168.3649 1134.5428
[1712,] 2880.2878 2974.8174 2949.9288 2781.0723 3109.7687 2949.6948
[1713,] 1561.0953 1511.8671 1445.4358 1669.2743 1411.0417 1756.3888
[1714,] 980.6150 918.8262 867.6766 1108.4348 814.6330 1115.0523
[1715,] 1692.7411 1687.9436 1637.1084 1729.5134 1657.6506 1571.6184
[1716,] 1847.0347 1821.7116 1756.5730 1919.6026 1754.4169 1639.6430
[1717,] 1293.0953 1280.2017 1238.0364 1334.4489 1241.8933 1294.5543
[1718,] 2010.8691 2018.1831 1965.1957 2032.9236 2005.5740 2341.5665
[1719,] 1636.7026 1690.9243 1670.8253 1583.4134 1769.0982 2392.9751
[1720,] 1305.6774 1299.3138 1259.6937 1337.0015 1271.5963 1306.4880
[1721,] 1879.7392 1902.7405 1859.7521 1876.5403 1918.8766 1816.4327
[1722,] 1666.1250 1650.8777 1596.1158 1719.1383 1603.3206 1544.1763
[1723,] 2258.6970 2270.9616 2215.0329 2276.5681 2264.3805 2071.0576
[1724,] 1412.1158 1423.4185 1389.6388 1418.0143 1425.4847 1651.6075
[1725,] 1863.2776 1852.1155 1793.4805 1913.1230 1808.7900 1754.8139
[1726,] 1687.3677 1701.0561 1659.1892 1695.0874 1703.1118 2030.7224
[1727,] 1461.9496 1377.9073 1299.3075 1630.7127 1225.4971 1496.2428
[1728,] 3221.9208 3249.3042 3184.1916 3225.4954 3262.4276 3198.8585
[1729,] 1538.9809 1588.5032 1569.6186 1490.5305 1659.6203 1648.6255
[1730,] 1586.3812 1600.8962 1563.0692 1590.6699 1606.1092 1407.7821
[1731,] 1932.7896 1931.5400 1875.0639 1968.3267 1904.0254 2115.9586
[1732,] 2594.8764 2707.5891 2696.2466 2467.9873 2877.1920 4788.0968
[1733,] 2456.1630 2344.9946 2225.4287 2673.7205 2131.1761 2402.9483
[1734,] 1944.0020 2034.4018 2024.8152 1840.8675 2176.3590 1963.4143
[1735,] 1911.5728 2249.6628 2379.1958 1506.3342 2915.5444 1814.5823
[1736,] 2898.2574 2922.2348 2859.8136 2905.2695 2930.8916 3106.8646
[1737,] 1645.7680 1671.9932 1637.6827 1633.5614 1697.3437 1531.2683
[1738,] 1550.0390 1660.3128 1672.7483 1419.8100 1854.1908 1010.3026
[1739,] 941.9534 773.4211 691.9986 1362.0337 587.7464 661.6160
[1740,] 1697.9207 1724.8843 1689.0581 1685.6893 1750.6890 1626.0109
[1741,] 2102.5242 2278.2349 2309.9361 1884.2863 2584.0380 1834.8883
[1742,] 3134.2496 3173.7955 3115.5880 3119.5403 3208.8725 3363.2203
[1743,] 2189.2355 2254.6892 2227.1501 2123.9388 2346.5704 2224.8249
[1744,] 968.0670 1020.9632 1023.0511 908.4277 1111.8409 1630.8666
[1745,] 3939.8756 4035.2439 4004.4270 3842.6423 4166.4609 4286.9137
[1746,] 1702.7956 1638.7994 1560.8316 1838.0282 1513.1087 2063.4744
[1747,] 667.8603 676.2773 668.5257 662.0387 685.8990 669.7667
[1748,] 2500.2352 2460.9926 2373.0686 2603.0910 2360.5648 2292.5267
[1749,] 1684.2225 1796.8671 1805.4182 1552.0206 1988.5638 1289.6542
[1750,] 1885.2571 1849.9550 1779.4203 1975.2259 1766.0086 2305.1512
[1751,] 1314.8429 1409.7422 1422.2288 1199.4585 1577.6297 1710.8316
[1752,] 2499.9137 2542.0474 2496.6359 2474.6994 2587.3841 2630.9728
[1753,] 1379.6215 1393.3731 1361.9005 1381.0992 1400.3317 1388.5035
[1754,] 2351.7660 2335.1886 2262.4118 2417.1744 2277.3807 2142.3569
[1755,] 1593.5422 1564.5288 1506.0492 1667.7824 1495.4964 1613.8348
[1756,] 4748.4187 4822.8066 4778.0231 4683.5526 4919.2594 4558.6275
[1757,] 1339.1788 1379.9580 1363.2315 1299.8065 1437.7423 1697.1475
[1758,] 1341.8031 1319.7966 1271.9328 1399.4808 1265.0899 1623.7219
[1759,] 1631.5013 1619.3740 1567.3223 1678.7191 1577.6447 1803.7521
[1760,] 1107.1801 1085.3643 1045.8404 1160.5627 1036.0614 1215.2166
[1761,] 2315.3561 2298.5681 2226.9408 2380.3529 2240.9755 1992.0245
[1762,] 2872.1484 2892.0441 2828.4735 2884.9409 2893.8165 2353.4939
[1763,] 1575.1987 1549.7566 1493.5514 1643.0749 1486.8442 1572.2806
[1764,] 2221.0754 2247.2099 2199.2659 2216.9017 2265.9605 2229.8107
[1765,] 1426.1202 1444.8834 1414.3256 1420.8263 1460.0467 1550.6727
[1766,] 2068.3836 2165.5129 2155.7931 1959.7472 2315.7121 2109.4226
[1767,] 814.8729 801.8013 777.6443 847.6032 771.7172 883.4929
[1768,] 377.6730 349.1719 331.8670 433.6285 305.3935 1943.9864
[1769,] 1641.6843 1596.2645 1528.7123 1744.7379 1500.3219 1634.5477
[1770,] 3222.0918 3283.9995 3239.1281 3170.0683 3360.0243 4131.3977
[1771,] 1622.8969 1625.5328 1580.7085 1646.4139 1609.1958 1573.3665
[1772,] 879.7382 846.1965 810.2466 949.9941 783.3794 926.0413
[1773,] 633.0694 606.6058 585.0834 687.9974 561.5580 713.2593
[1774,] 1197.8920 1172.6978 1128.0616 1258.6807 1115.6525 1400.8758
[1775,] 2490.0243 2466.1237 2386.4715 2567.5044 2393.2517 2328.5353
[1776,] 1624.0528 1629.8343 1586.4574 1642.6712 1618.9688 1814.3490
[1777,] 1544.8978 1574.2863 1545.1677 1525.8799 1607.2121 1616.0849
[1778,] 1878.7711 1865.7415 1805.6835 1931.9593 1819.0065 2175.4877
[1779,] 1493.5877 1459.9524 1402.4132 1573.5192 1384.5127 1536.7482
[1780,] 1159.5708 1188.0929 1170.4177 1135.2016 1225.2699 1067.3397
[1781,] 1001.3080 1125.1965 1166.2778 860.3091 1379.3913 1161.8723
[1782,] 1528.3812 1568.1984 1544.8266 1493.7096 1620.9240 1323.6783
[1783,] 3877.4939 3918.7271 3862.0970 3859.7411 3957.1139 3531.9001
[1784,] 1735.2431 1736.9203 1687.6127 1762.6850 1717.0944 1827.1831
[1785,] 1687.8025 1667.8389 1610.1231 1748.9775 1612.0651 1774.4518
[1786,] 2284.0340 2376.3043 2359.2250 2184.4399 2513.7185 2284.0583
[1787,] 1997.7922 2029.5855 1989.4610 1982.1389 2061.0085 1829.8694
[1788,] 723.9350 740.2462 734.0619 707.7807 764.5738 796.1183
[1789,] 3064.5694 3111.2839 3058.7689 3037.8191 3160.4353 3261.8349
[1790,] 1598.1647 1598.3396 1553.2547 1625.0276 1578.1531 1425.1753
[1791,] 1156.7621 1180.8346 1161.0225 1138.8955 1209.7220 1026.0450
[1792,] 2801.6882 2749.8080 2652.2874 2928.2866 2626.6572 2562.3879
[1793,] 806.8311 791.7622 766.8421 842.8480 758.3541 1001.9605
[1794,] 2191.1853 2216.1006 2167.2475 2188.4343 2232.7895 2190.6512
[1795,] 1150.7829 1135.7315 1097.3719 1193.7422 1096.0635 1157.6734
[1796,] 1318.2328 1277.5366 1221.6325 1406.1114 1193.2748 954.3844
[1797,] 1627.5329 1742.0667 1753.7857 1492.9816 1940.1493 2250.6047
[1798,] 1728.6858 1690.8284 1623.4906 1819.4569 1605.2124 1831.9680
[1799,] 1932.2137 1849.8947 1756.3209 2098.6534 1690.3844 1890.9032
[1800,] 708.9213 655.9577 622.4762 824.8346 580.2067 832.8759
[1801,] 1868.4297 1919.8087 1891.1654 1822.9137 1988.1054 1566.9789
[1802,] 1961.6071 1945.1505 1880.5282 2019.8949 1891.2862 1887.4484
[1803,] 932.3288 894.0407 854.6336 1012.0465 823.6311 929.9275
[1804,] 535.5286 523.1305 509.5907 560.0700 498.9109 540.6050
[1805,] 1939.4756 1980.1149 1943.7992 1910.8690 2025.4259 2032.2544
[1806,] 1539.5548 1543.9993 1502.9968 1558.4424 1532.1734 1342.9711
[1807,] 1592.6187 1626.0186 1597.1310 1568.6633 1665.5227 1216.6484
[1808,] 1974.6178 1970.4219 1911.0503 2013.8238 1937.1521 1888.7640
[1809,] 2679.4171 2618.4799 2518.3672 2812.7928 2484.5009 2284.3656
[1810,] 1348.2171 1347.7038 1310.4757 1371.2041 1330.0440 1434.3035
[1811,] 1186.0094 1303.2554 1331.2138 1046.0357 1520.8016 1063.3019
[1812,] 1331.0277 1250.7789 1177.2533 1489.4598 1107.6078 1047.2807
[1813,] 1591.6885 1541.9792 1474.2594 1701.3211 1440.1857 1684.7219
[1814,] 1649.5267 1670.4216 1633.3852 1645.4393 1686.0244 1313.7604
[1815,] 2779.7799 2764.8241 2687.4689 2845.5508 2707.2980 2477.1284
[1816,] 2014.3153 2024.3874 1972.9779 2032.1505 2016.5688 1596.6917
[1817,] 1243.4040 1223.1718 1179.3363 1296.7945 1173.5329 1309.6603
[1818,] 2957.5729 2897.7642 2793.7485 3093.1492 2762.8394 3050.0229
[1819,] 1206.5541 1203.7221 1169.2369 1230.9050 1183.8143 1447.1840
[1820,] 4436.1306 4581.7689 4580.2429 4255.2994 4816.0912 4249.6334
[1821,] 910.9464 963.6166 968.5261 849.2164 1058.3799 959.0139
[1822,] 504.5507 498.1456 487.9731 518.8580 483.9543 1354.6620
[1823,] 2990.2293 3086.0846 3060.5866 2887.0710 3228.8854 2991.7891
[1824,] 2267.2515 2290.0859 2238.9605 2269.0345 2302.1672 2394.6549
[1825,] 1953.0386 1965.9859 1915.5163 1966.8151 1962.9390 2453.9183
[1826,] 1777.6339 1766.4120 1709.5247 1825.2932 1723.7991 1763.8744
[1827,] 4448.5005 4118.1138 3857.0810 5040.9498 3471.9807 4930.9651
[1828,] 1412.0533 1690.6523 1809.4126 1093.7518 2302.6497 902.0919
[1829,] 1120.9166 1147.4655 1130.0921 1098.7472 1181.6172 1127.9486
[1830,] 2302.5214 2246.8266 2156.0332 2431.8155 2122.5524 2135.1730
[1831,] 472.8428 463.3834 452.2765 491.8665 444.4956 766.6622
[1832,] 2308.3075 2433.3277 2432.4182 2163.5198 2628.5465 2354.4443
[1833,] 4884.8654 4904.4682 4829.1427 4904.8576 4900.5252 5468.5599
[1834,] 1234.2341 1234.8052 1200.9937 1253.7749 1220.3379 1355.4821
[1835,] 1591.0295 1612.0891 1577.2440 1585.4680 1628.9832 2005.0890
[1836,] 3968.2440 3794.3110 3617.8545 4282.2685 3441.0877 3694.2083
[1837,] 3364.7546 3400.5458 3338.8646 3356.6728 3428.0593 2754.9993
[1838,] 1541.7924 1664.5243 1684.0761 1395.5682 1885.4988 1282.2528
[1839,] 1180.0085 1287.1650 1310.1963 1051.9202 1482.8430 1412.7810
[1840,] 743.5352 702.5579 670.9638 829.9020 637.5292 767.7187
[1841,] 3153.0384 3012.0127 2864.9284 3424.5844 2739.9559 3544.5758
[1842,] 1385.5802 1436.7113 1423.5937 1332.3806 1512.7553 1269.1591
[1843,] 1574.6490 1581.0081 1539.6890 1591.2878 1571.9746 1529.1490
[1844,] 797.2446 884.9108 915.0371 697.5453 1071.8618 944.6262
[1845,] 772.2271 734.0414 701.6222 850.7898 670.9234 971.3061
[1846,] 1632.0255 1629.5138 1581.9313 1663.8601 1604.1253 1580.5321
[1847,] 1413.1687 1388.0979 1337.2083 1476.9201 1328.2471 1177.0260
[1848,] 915.2894 944.4216 936.7975 884.8765 988.7153 974.7398
[1849,] 3275.7843 3295.6210 3228.4741 3290.5908 3295.8048 3077.1813
[1850,] 3520.3243 3492.5086 3395.5174 3606.0791 3406.9459 3073.8017
[1851,] 2078.0553 1924.9482 1794.6830 2372.7881 1654.8906 3034.0602
[1852,] 4528.8536 4574.6657 4519.7126 4504.4807 4620.9733 5298.1443
[1853,] 1577.4164 1554.2778 1499.0514 1641.5170 1495.1034 1287.9732
[1854,] 2197.3617 2091.1788 1980.9550 2406.2228 1889.9097 2798.4339
[1855,] 1188.5533 1108.1640 1040.6034 1348.3693 972.1595 1519.2523
[1856,] 1718.4020 1759.8381 1730.3763 1685.1387 1811.2059 1342.9195
[1857,] 1167.5864 1137.2138 1091.2931 1236.5158 1072.5159 1978.5410
[1858,] 4169.6262 4112.8834 3997.7504 4304.8198 3966.5246 4213.8346
[1859,] 1671.9671 1624.8100 1555.3788 1778.5877 1525.5755 1938.0107
[1860,] 1280.5326 1265.8946 1223.3562 1324.7644 1224.8802 1188.9369
[1861,] 1534.4633 1483.1375 1416.4332 1645.8023 1379.2050 1503.2095
[1862,] 909.8964 913.7477 893.6916 916.9761 910.5579 657.3234
[1863,] 756.7462 742.8009 721.2743 789.8309 713.4684 626.4886
[1864,] 1224.2481 1165.3234 1104.8625 1343.8029 1056.3321 944.5697
[1865,] 928.9339 934.7417 915.0619 933.3290 934.7490 924.4402
[1866,] 2110.4608 2148.0929 2106.8666 2088.3477 2188.3211 1288.2725
[1867,] 1107.6021 1138.6113 1123.9246 1078.7017 1181.4350 1147.0127
[1868,] 3540.6106 3607.1637 3563.8099 3480.1431 3692.3089 3644.3972
[1869,] 1086.4726 1030.5542 977.1090 1201.4827 931.3792 859.6601
[1870,] 2108.1001 2097.2700 2032.8960 2160.8960 2051.8135 2070.6208
[1871,] 1172.4314 1225.7611 1220.2720 1113.0962 1310.8413 1077.3167
[1872,] 2491.3991 2502.9595 2442.9401 2512.5834 2493.4389 2967.0929
[1873,] 1026.8337 1009.1611 974.3866 1071.4865 967.4284 1120.0624
[1874,] 2340.7656 2403.3132 2369.1837 2284.8969 2484.0003 2600.8252
[1875,] 962.7803 972.3438 953.1520 962.3490 978.4367 1251.3297
[1876,] 2281.4047 2281.5013 2218.9891 2318.7637 2253.2999 2094.1449
[1877,] 1420.7994 1402.3421 1354.2272 1473.7846 1353.2096 1214.4257
[1878,] 1999.6311 2116.5738 2119.7603 1858.6700 2309.7139 1779.6924
[1879,] 850.7992 818.1371 784.2869 918.1445 757.9525 1097.0627
[1880,] 2386.6276 2425.3443 2377.8251 2366.7931 2462.3086 1362.6377
[1881,] 1385.5600 1361.1248 1311.4758 1448.0558 1302.7604 1427.2400
[1882,] 1925.6871 1770.1981 1644.2153 2224.9571 1506.4461 1778.6323
[1883,] 693.7185 717.3934 715.9213 668.3529 756.1474 959.2388
[1884,] 759.6127 735.9477 709.9321 810.2801 691.7980 802.9367
[1885,] 806.2151 759.6176 722.6521 900.9405 684.4626 1594.7816
[1886,] 1911.9133 1779.4078 1663.3335 2169.5112 1546.4982 1609.5505
[1887,] 1063.6778 1066.3046 1039.8192 1076.5179 1058.1953 1016.6397
[1888,] 1625.6680 1655.7826 1624.0942 1607.2345 1688.6167 1646.1582
[1889,] 1877.8868 1853.1855 1787.7589 1950.0839 1786.9816 1907.0162
[1890,] 809.4524 829.0720 820.4127 791.2490 856.4643 845.8943
[1891,] 2535.4563 2523.3446 2450.5968 2594.8238 2472.1575 2577.7561
[1892,] 854.3245 875.6544 866.5108 833.8453 906.0673 675.0019
[1893,] 2321.8384 2340.1944 2285.0298 2331.5964 2343.4114 1976.8363
[1894,] 719.8123 765.7599 775.4393 667.1391 854.4908 725.2328
[1895,] 1557.5877 1467.9896 1383.6185 1739.5809 1306.5875 1739.2502
[1896,] 1558.7211 1562.2640 1520.1622 1579.4226 1548.5591 1402.4970
[1897,] 1130.1142 1172.7828 1163.2261 1085.0204 1237.6311 1072.0671
[1898,] 1039.0889 1017.5478 980.6019 1090.9548 969.3535 1010.0114
[1899,] 2769.5935 2827.3055 2785.5982 2723.4908 2899.4156 2538.5562
[1900,] 2704.0285 2711.5359 2644.5574 2732.8552 2693.8772 2702.2081
[1901,] 3172.8856 3164.1137 3081.3062 3233.6701 3113.3487 3015.8191
[1902,] 3138.1680 3228.7720 3195.9535 3048.2393 3350.4498 3761.9289
[1903,] 1158.6445 1103.9393 1048.0369 1270.6023 1003.9842 1549.6585
[1904,] 1467.8413 1545.0396 1542.9494 1379.1890 1672.9735 1739.3152
[1905,] 1080.2218 1143.1514 1145.9143 1008.2509 1250.3459 1315.7296
[1906,] 1771.6907 1821.6381 1795.7056 1725.4476 1889.3237 1836.5759
[1907,] 1084.9673 1039.5435 990.6743 1180.2446 954.8288 1660.6447
[1908,] 1656.2627 1658.5240 1612.3181 1681.0818 1640.9972 1825.7691
[1909,] 1057.5175 1146.3815 1164.1836 953.8070 1311.1304 941.1778
[1910,] 2089.4377 2194.6175 2188.3100 1970.7322 2358.5640 1809.4977
[1911,] 2295.2677 2284.1417 2215.8554 2350.7468 2236.4590 2193.3135
[1912,] 849.0212 891.7465 893.8131 799.2548 965.6361 1056.2068
[1913,] 5146.1306 5242.8646 5202.9043 5051.7608 5374.1424 5247.6811
[1914,] 942.0215 992.7031 995.0388 883.6468 1080.8298 1000.0234
[1915,] 833.2790 808.2557 778.3606 886.2489 759.7255 743.8003
[1916,] 931.5547 847.0987 789.4581 1109.4595 719.3577 753.7673
[1917,] 3139.3180 3144.9065 3070.0159 3176.9372 3119.4895 3026.1616
[1918,] 2381.1672 2466.5679 2445.1001 2290.2052 2589.7107 3325.9896
[1919,] 1089.9464 1113.0545 1095.0265 1072.2475 1141.3143 1360.5393
[1920,] 1739.3430 1829.1521 1824.3170 1636.7410 1974.7576 1368.3902
[1921,] 1043.6456 1004.6800 960.0172 1126.7217 930.5753 1026.7268
[1922,] 1464.1568 1479.7391 1446.7078 1464.2811 1488.8458 1225.0425
[1923,] 1377.3806 1311.2692 1241.7901 1512.1153 1185.7836 1522.5296
[1924,] 1364.7697 1282.8036 1206.8800 1528.0431 1134.9926 2007.1931
[1925,] 2674.4753 2647.9355 2563.8204 2754.9115 2570.2847 2818.1070
[1926,] 813.9540 819.8487 804.4264 815.8656 821.8297 851.0757
[1927,] 1703.7811 1678.0503 1617.1150 1774.8022 1612.4998 2478.4981
[1928,] 1655.1016 1656.8882 1610.4988 1680.6419 1638.5558 1860.8175
[1929,] 551.5326 615.9942 646.3134 472.2886 785.8425 427.4972
[1930,] 1396.3083 1369.9825 1319.1004 1462.0087 1308.3734 1407.4669
[1931,] 2030.3105 2030.1042 1973.2590 2064.5673 2004.0936 1934.9026
[1932,] 1550.1739 1613.5395 1601.2633 1482.4543 1711.5454 1385.6736
[1933,] 1310.2147 1246.4739 1180.9289 1437.7261 1128.1106 1259.0652
[1934,] 5305.7864 5296.7043 5200.1543 5371.5873 5239.2777 5177.7733
[1935,] 1085.0146 1096.9388 1073.5847 1083.9761 1104.8029 1211.2724
[1936,] 1629.3458 1602.4924 1543.7495 1700.6699 1536.4230 2073.6049
[1937,] 1449.1555 1363.9960 1285.0563 1619.5922 1210.1659 1348.2855
[1938,] 2783.0638 2866.6199 2837.4818 2699.6213 2985.6016 2847.8378
[1939,] 1144.7082 1149.1650 1120.1937 1156.3668 1142.8344 958.8508
[1940,] 1416.7363 1381.8993 1326.4538 1496.8021 1306.3071 1541.6937
[1941,] 1884.0929 1656.9622 1506.4620 2325.8708 1311.3583 2289.1740
[1942,] 3275.5222 2951.7189 2717.2578 3846.9228 2395.2798 3328.7330
[1943,] 1247.3069 1301.2927 1293.4686 1188.3833 1383.8001 1069.3244
[1944,] 946.1151 878.4520 826.6047 1085.6643 768.6562 1212.4118
[1945,] 1113.5611 1107.5585 1074.6732 1141.1142 1083.6364 1325.0460
[1946,] 533.1521 544.6723 543.1007 520.1831 562.2756 889.6845
[1947,] 979.6930 1072.8188 1097.1351 871.5716 1255.9066 1557.2478
[1948,] 1688.2286 1838.2383 1867.1046 1508.2286 2106.8223 1399.4071
[1949,] 1575.5325 1585.7310 1546.2170 1586.2323 1583.4478 1754.8204
[1950,] 1183.9796 1251.9990 1253.7935 1105.0165 1365.3770 983.9253
[1951,] 761.1569 766.7064 752.9159 762.3827 769.0178 822.4474
[1952,] 754.5660 798.5684 804.8464 704.5698 878.1101 860.0188
[1953,] 2333.8333 2285.7379 2199.0410 2449.7466 2175.3665 2344.5000
[1954,] 1791.0098 1865.4826 1851.3389 1709.6560 1980.6332 1701.6671
[1955,] 1431.5092 1420.2153 1375.0541 1473.0403 1382.8633 1407.0505
[1956,] 442.7443 447.4891 443.9762 438.9627 453.3085 495.9624
[1957,] 1199.2752 1173.7978 1128.9842 1260.5729 1116.2698 1147.8450
[1958,] 2132.1376 2145.4474 2091.6675 2147.4203 2141.4553 2289.1021
[1959,] 1036.9276 964.3564 907.4432 1185.0139 846.3230 1248.5315
[1960,] 1816.4500 1822.8591 1774.0818 1837.4432 1810.5457 1958.5019
[1961,] 769.6396 765.5039 746.8940 786.1657 750.8007 865.2710
[1962,] 838.1479 864.0878 857.7695 810.8208 903.4939 1073.3913
[1963,] 1428.0231 1364.6347 1296.0521 1557.9098 1243.5639 1122.3246
[1964,] 2321.4016 2309.2583 2239.6003 2379.0500 2259.4381 2012.7408
[1965,] 1561.0486 1540.0492 1486.3788 1621.2536 1484.6647 1564.2346
[1966,] 3077.8943 3037.5437 2942.1983 3187.9965 2933.8334 3141.9333
[1967,] 901.1159 875.6768 842.9298 956.3724 824.8341 816.7414
[1968,] 1038.0358 1015.1429 977.6128 1092.1968 964.8698 933.4762
[1969,] 1448.8050 1414.5918 1358.2609 1528.3338 1339.2552 1409.0551
[1970,] 1299.8386 1226.9894 1158.0378 1443.3187 1096.1582 1283.1312
[1971,] 2589.1289 2499.0616 2385.9982 2774.1810 2313.9097 2192.5656
[1972,] 691.3607 688.0099 673.8907 704.6880 676.5690 683.0370
[1973,] 2095.9821 2016.6803 1918.9179 2261.3073 1855.8946 1378.5977
[1974,] 1112.8048 1073.3692 1026.2373 1196.6283 997.2648 1415.3889
[1975,] 932.9368 932.2781 909.3517 947.4878 920.8941 1028.2463
[1976,] 3016.3239 2990.7842 2902.2390 3101.1814 2911.5606 2724.4430
[1977,] 1709.2714 1720.0292 1675.9725 1721.9815 1716.5282 1288.0056
[1978,] 1562.5351 1488.4160 1410.7408 1715.5060 1349.4918 1603.5739
[1979,] 1958.1882 1956.9007 1899.4908 1993.4878 1928.9044 2005.0959
[1980,] 2316.6039 2399.1799 2375.9963 2231.6361 2516.6381 2298.6188
[1981,] 1810.6201 1763.6528 1688.8535 1918.2617 1660.7402 2108.2246
[1982,] 2086.2533 2078.2875 2016.0204 2134.0042 2038.0574 2612.6209
[1983,] 1602.8387 1570.5447 1510.2494 1682.7791 1496.0622 1973.8309
[1984,] 4673.2607 4745.5579 4701.3098 4610.3594 4838.8270 4625.6632
[1985,] 1423.0491 1505.6426 1507.9198 1326.4731 1645.5263 1598.5866
[1986,] 2287.7723 2217.0214 2118.3682 2442.1579 2067.0566 2257.3073
[1987,] 3419.8251 3426.0054 3348.2547 3458.3581 3400.2138 4172.7891
[1988,] 1782.0908 1752.9036 1687.5205 1858.6769 1680.1845 1723.6610
[1989,] 1277.4741 1303.8756 1281.1798 1258.3901 1334.3270 1544.7269
[1990,] 2097.4196 2117.0121 2067.4737 2102.3043 2124.7491 2002.7264
[1991,] 987.6880 993.0082 970.3412 994.4783 990.8899 1003.9125
[1992,] 1552.8835 1451.9952 1362.8683 1756.6976 1274.0120 2131.2000
[1993,] 807.2560 894.8614 924.2112 707.5529 1080.1028 965.7622
[1994,] 1341.4625 1355.4998 1325.4793 1341.7288 1363.5808 1162.7289
[1995,] 1169.8540 1188.7073 1165.9005 1159.9816 1207.8013 1146.3212
[1996,] 1777.9632 1850.2461 1835.4597 1699.1767 1961.5152 1750.1292
[1997,] 1323.3164 1343.2309 1316.6947 1314.3177 1362.2368 1613.0746
[1998,] 1387.0604 1472.3397 1477.1202 1286.6470 1617.9505 1000.9190
[1999,] 1339.2506 1428.3570 1436.8012 1232.3684 1582.7723 1456.6216
[2000,] 1128.4736 1145.7423 1123.5275 1120.2100 1162.6009 1158.3650
[2001,] 1086.1670 1049.8593 1004.9918 1164.7238 978.5257 1107.6799
[2002,] 1559.1298 1611.1957 1592.8481 1507.4491 1686.8244 1586.9232
[2003,] 1024.9890 1071.5865 1068.2604 972.6452 1148.6798 1366.1334
[2004,] 2340.0193 2281.4865 2189.5952 2472.2673 2153.3917 2247.3381
[2005,] 2087.3235 2146.2545 2116.3992 2033.4921 2225.3664 1955.3025
[2006,] 1216.4883 1236.3849 1212.5067 1205.9827 1256.6384 1279.8133
[2007,] 1419.7504 1461.1857 1442.3233 1380.5793 1518.4972 1360.4674
[2008,] 1077.0529 1090.1975 1067.7050 1074.0033 1100.3869 939.2141
[2009,] 2117.3716 2223.5828 2217.7427 1996.2313 2391.2905 2031.0080
[2010,] 968.4304 1019.7052 1020.9216 910.8698 1107.0795 1124.0618
[2011,] 495.8973 504.2091 501.6280 487.2604 516.1060 433.1078
[2012,] 1656.5191 1668.2881 1626.6040 1666.5385 1667.4438 2301.9822
[2013,] 1128.2024 1132.2152 1103.5898 1140.2177 1125.3603 1344.4923
[2014,] 1235.3165 1208.1963 1161.4693 1300.1017 1147.4921 1507.8520
[2015,] 1109.4445 1108.3977 1077.9920 1129.0226 1093.0270 1291.6467
[2016,] 1565.7856 1512.3879 1443.9483 1681.3884 1404.9889 1478.7727
[2017,] 1285.0905 1335.0521 1324.6303 1230.9914 1410.8630 1576.7894
[2018,] 2921.1508 2950.8850 2890.5350 2919.7912 2968.6390 2587.2218
[2019,] 1543.5221 1496.0847 1430.9602 1648.2201 1398.2034 1303.5858
[2020,] 1554.7323 1575.5727 1541.9284 1548.7282 1592.6837 1249.8829
[2021,] 994.0350 976.7418 944.0798 1037.2608 937.2788 1741.1427
[2022,] 1174.6015 1210.4754 1195.9904 1139.8071 1261.4260 1399.2291
[2023,] 731.5452 752.6684 748.2664 709.0002 786.8567 863.1006
[2024,] 1694.9724 1728.2879 1695.6748 1673.1995 1765.8188 1602.6184
[2025,] 1550.0277 1568.3140 1533.5954 1547.7990 1580.8872 1513.0924
[2026,] 1108.3785 1145.0217 1133.1515 1071.4182 1198.6192 1248.4431
[2027,] 1232.6368 1267.8720 1251.0354 1199.9011 1316.0862 1090.0064
[2028,] 937.9030 934.6728 910.3656 956.6164 918.7883 1619.4153
[2029,] 1171.3339 1179.7881 1151.8479 1177.3177 1180.1189 1115.7933
[2030,] 1603.7277 1515.8844 1431.1573 1782.8511 1356.3928 1521.6099
[2031,] 1260.7871 1280.1834 1254.5210 1251.9195 1298.7875 1238.6749
[2032,] 7419.5480 7420.4486 7350.9348 7459.3486 7390.5014 7368.2401
[2033,] 2255.2074 2203.7457 2114.7123 2376.3848 2085.4533 2213.1515
[2034,] 2783.4400 2808.9477 2750.9214 2785.9514 2822.0260 2675.2112
[2035,] 1012.4284 965.3818 919.6593 1109.2831 881.5541 1001.2413
[2036,] 756.0842 763.4685 750.7216 754.4252 769.1320 786.6438
[2037,] 1474.9915 1502.0740 1474.2774 1458.0077 1531.9265 1566.9327
[2038,] 1548.4004 1520.1402 1463.5829 1620.4002 1453.0843 1151.3026
[2039,] 1530.0255 1562.5442 1535.4932 1506.0763 1601.5242 1419.8578
[2040,] 3495.9172 3338.2556 3179.3046 3783.8131 3035.2478 4662.5722
[2041,] 1182.6495 1078.7330 1002.9005 1389.2751 915.7063 1880.9761
[2042,] 1393.0339 1328.5975 1259.7786 1524.7470 1205.7291 1594.4121
[2043,] 727.0277 764.0159 768.2849 684.6308 831.4947 1028.1775
[2044,] 734.8758 681.3886 645.6012 850.5647 603.3553 844.5516
[2045,] 1393.2678 1378.9438 1333.6912 1439.3448 1337.1181 1398.3643
[2046,] 613.3933 623.9727 619.6628 603.5712 638.8494 691.5034
[2047,] 928.8426 909.0608 877.4607 974.7993 866.2952 881.6263
[2048,] 1966.2152 1977.9732 1926.5286 1981.7989 1972.7378 1597.5014
[2049,] 4292.2205 4283.9642 4202.0735 4351.4224 4234.4163 4381.1216
[2050,] 943.9716 885.7670 837.8644 1063.0805 788.1450 988.4658
[2051,] 1020.3326 995.3016 957.7254 1077.4189 942.7613 1087.7052
[2052,] 2176.4602 2118.8873 2030.7059 2303.1731 1995.8320 2570.5421
[2053,] 1789.4599 1768.4249 1706.4156 1853.3852 1708.6696 1530.8140
[2054,] 879.9332 856.6143 825.2184 931.7846 808.7790 904.6533
[2055,] 612.9917 591.6333 572.4833 656.9613 552.9688 665.7639
[2056,] 1189.1769 1214.3274 1193.9812 1170.3156 1244.7400 1441.9557
[2057,] 1322.0211 1284.6939 1230.1020 1404.4749 1205.4236 1197.4450
[2058,] 1875.8979 2093.2828 2154.2490 1608.0065 2496.2944 1484.2009
[2059,] 965.4866 872.7505 810.4818 1163.3051 733.3944 1203.9296
[2060,] 978.8881 1062.7134 1081.7467 881.0594 1224.0127 969.7750
[2061,] 1891.5868 1864.4318 1797.3897 1968.1234 1793.9573 1535.1591
[2062,] 944.7314 918.3460 883.0855 1003.3269 864.8725 1039.8170
[2063,] 910.8139 858.6816 813.9845 1017.5025 769.6230 1215.7541
[2064,] 655.6241 645.6671 630.4214 679.6849 624.5061 762.4020
[2065,] 1659.1277 1626.8397 1564.5430 1740.1585 1551.4297 1653.4295
[2066,] 2435.6988 2386.0801 2295.0952 2549.8220 2272.1569 2203.8955
[2067,] 630.3456 612.9092 595.5579 666.4568 581.2353 740.3107
[2068,] 583.9416 583.5199 574.9269 589.6572 578.9974 726.9503
[2069,] 1011.9585 1119.3462 1150.1257 887.6597 1332.1893 932.7132
[2070,] 955.2431 920.4860 881.1950 1029.7004 854.1811 1048.9279
[2071,] 958.1717 962.2419 940.8307 965.7842 958.7713 1108.4449
[2072,] 719.4486 710.8137 692.7594 741.7164 690.2035 771.8969
[2073,] 2033.2259 1813.7196 1657.9183 2453.2437 1463.6934 1573.3410
[2074,] 1228.8783 1224.1827 1188.0655 1256.6589 1200.7358 1357.2553
[2075,] 990.2621 1011.5511 996.6429 972.9970 1038.4016 1128.3067
[2076,] 1250.3038 1244.4812 1207.0972 1280.3310 1218.7767 1090.8477
[2077,] 1067.0824 1077.3178 1054.0119 1068.2662 1082.4297 1228.6687
[2078,] 783.0397 755.5610 727.2948 839.8735 706.2011 672.1006
[2079,] 914.4735 925.8827 909.3841 910.0569 936.1385 844.2640
[2080,] 1125.9891 1105.1173 1064.9153 1178.1465 1056.5136 1269.1957
[2081,] 1142.4728 1140.2803 1108.2190 1164.5362 1122.4301 1412.7020
[2082,] 1123.9048 1089.0149 1043.0989 1199.9277 1019.1637 1087.1651
[2083,] 616.8284 625.6826 620.3660 609.4638 637.1478 830.9233
[2084,] 1624.8423 1681.4013 1662.9147 1568.0334 1764.3506 1561.8364
[2085,] 1359.2982 1327.4435 1274.5684 1433.8852 1256.3205 1777.3002
[2086,] 1079.5777 1041.3253 995.7262 1161.8446 966.8574 1060.2019
[2087,] 744.7375 715.5885 687.8053 806.9722 664.1608 564.9408
[2088,] 1389.5728 1440.9942 1427.9097 1336.0093 1517.5174 1059.4812
[2089,] 1173.2807 1191.1968 1167.8215 1164.8740 1208.5358 1564.7468
[2090,] 645.7873 607.0749 580.2318 730.4152 545.4615 624.6133
[2091,] 1269.4647 1252.6404 1209.4744 1317.2797 1208.1811 1335.3820
[2092,] 884.9644 779.2173 717.6801 1119.7892 639.3372 733.6464
[2093,] 2565.7099 2737.5503 2757.4495 2352.2230 3022.4152 2808.6128
[2094,] 1254.7511 1279.7362 1257.0278 1237.4243 1308.5087 1319.6666
[2095,] 1137.7351 1051.8772 984.8286 1310.0765 912.8020 1236.8246
[2096,] 2176.9221 2198.0408 2146.6110 2180.9470 2207.0062 2080.7267
[2097,] 1858.6258 1962.3499 1960.8627 1739.3441 2127.5063 1742.3421
[2098,] 971.9466 971.9090 947.9081 986.8015 960.8747 1050.8571
[2099,] 1034.8275 1019.2920 985.2490 1076.2071 980.9384 1010.8714
[2100,] 1514.4419 1579.8390 1569.9252 1443.2834 1682.6982 1642.8481
[2101,] 3219.1176 3264.7416 3210.3004 3193.3324 3310.5055 3155.3982
[2102,] 822.6897 862.9181 864.5116 776.4492 931.8630 833.7771
[2103,] 851.0566 833.6963 806.0743 891.1570 796.2297 1005.2297
[2104,] 1013.0527 1162.5479 1218.4024 846.5704 1479.4906 798.3092
[2105,] 979.8031 1021.8911 1017.9119 934.0109 1089.8373 816.2637
[2106,] 825.4128 813.0697 789.0848 856.5472 784.5337 761.5849
[2107,] 2150.9700 2208.9583 2177.2973 2098.8114 2284.1008 2080.9279
[2108,] 798.5387 743.0511 703.4031 912.0862 658.8538 835.2235
[2109,] 1042.1335 1094.9786 1094.0829 982.3673 1183.5164 1115.1087
[2110,] 2553.3669 2563.1100 2500.1758 2578.5988 2549.4623 2655.2905
[2111,] 917.8944 878.2045 838.8033 999.7747 806.1902 941.5109
[2112,] 1219.2476 1270.5617 1262.3669 1163.5326 1349.4124 2919.0297
[2113,] 1422.9909 1374.9160 1313.3469 1525.7608 1277.9084 1067.9264
[2114,] 1814.3964 1767.3709 1692.3603 1922.3716 1664.1391 1145.4644
[2115,] 983.6081 1015.3377 1005.9067 951.7074 1062.1452 928.8845
[2116,] 1042.5726 1014.4189 974.3533 1106.1588 956.0602 1061.7009
[2117,] 1769.7927 1859.6660 1854.1553 1666.4694 2004.7672 1613.8046
[2118,] 1538.4180 1550.5714 1513.2987 1545.3266 1552.3544 1176.6443
[2119,] 1007.2414 1038.7106 1028.3732 975.5111 1085.1303 916.5304
[2120,] 1239.2045 1270.2031 1251.0188 1212.7366 1310.4304 1196.8132
[2121,] 3349.6929 3408.5629 3358.7647 3306.6487 3478.3800 3245.7352
[2122,] 724.5697 779.1845 793.3237 662.5646 887.3786 949.3883
[2123,] 1134.8351 1108.6722 1065.7622 1196.0467 1051.5401 1326.6535
[2124,] 2250.0854 2345.3204 2330.9691 2144.0637 2490.9249 2131.5109
[2125,] 1681.0254 1613.3470 1534.5886 1822.8823 1482.5933 1712.4732
[2126,] 770.7329 792.9693 787.3080 747.4270 826.5429 836.7146
[2127,] 1375.2291 1367.4991 1325.9431 1410.2651 1337.0570 1893.3719
[2128,] 608.2312 603.9241 592.8036 620.7395 592.4164 963.7022
[2129,] 407.0606 420.4595 422.1588 390.5479 443.1974 653.3906
[2130,] 2128.4619 2136.8589 2080.8600 2151.2942 2124.2754 2312.4005
[2131,] 690.5327 682.0414 665.4522 712.7772 661.8989 680.9752
[2132,] 454.3151 483.1960 492.4057 417.3521 536.5668 592.9337
[2133,] 1151.4150 1127.5673 1085.1490 1208.9992 1073.5392 1185.2076
[2134,] 1544.9815 1468.9318 1390.8205 1701.2488 1327.3467 2493.3418
[2135,] 1636.2839 1655.3334 1617.8764 1634.7214 1667.8292 1792.7883
[2136,] 629.3625 679.3723 696.3129 572.3527 791.0756 913.6854
[2137,] 1063.1653 1099.4481 1088.9646 1026.8236 1153.3192 1118.3376
[2138,] 796.2768 775.7071 748.5258 841.3661 734.7084 919.7827
[2139,] 1484.5111 1469.9425 1421.6886 1532.5693 1426.3116 1532.7327
[2140,] 1336.4035 1335.7111 1298.7273 1359.4302 1317.9249 1042.6225
[2141,] 658.4033 656.4119 644.5160 668.5071 648.0872 646.3075
[2142,] 5399.1736 5317.1099 5180.5435 5581.4059 5126.4398 5062.2718
[2143,] 1224.0760 1131.4660 1057.2047 1406.8409 977.9700 2387.9592
[2144,] 1314.6224 1280.6952 1227.9892 1390.8999 1207.2415 1552.7638
[2145,] 1173.0974 1219.8283 1210.9144 1122.9060 1291.9833 967.4468
[2146,] 1261.0078 1251.5056 1212.0296 1297.1756 1219.3988 1328.2760
[2147,] 599.6199 561.8509 535.7014 677.9502 499.3705 690.1784
[2148,] 1605.2686 1668.9313 1654.7692 1538.1584 1766.2270 1937.5972
[2149,] 1704.4148 1412.7639 1246.6057 2319.8828 1012.0188 1071.2069
[2150,] 1215.4662 1253.2631 1238.3179 1178.7336 1306.9762 973.3222
[2151,] 1684.9900 1662.2932 1603.4195 1750.5986 1602.0454 2780.1260
[2152,] 1291.9800 1334.6861 1320.4350 1248.2278 1396.5636 1189.1657
[2153,] 1503.1008 1511.2372 1473.2682 1515.4786 1506.4721 1585.5553
[2154,] 1125.2335 1033.0042 963.7926 1311.6352 886.5226 1884.6000
[2155,] 800.3428 799.7890 781.9503 811.6906 790.8741 900.9379
[2156,] 1532.9802 1621.4575 1622.8913 1430.8666 1771.1952 1352.5467
[2157,] 2215.7307 2207.9315 2141.5680 2264.2607 2165.8580 1216.2870
[2158,] 1351.0491 1320.9751 1269.0355 1422.4520 1252.7364 1350.1339
[2159,] 952.1187 875.5819 819.9825 1111.6917 754.5981 1593.7820
[2160,] 1523.9907 1529.6612 1489.7861 1540.6383 1520.2286 1537.0236
[2161,] 4539.4307 4515.9768 4426.4082 4622.7478 4440.0984 4728.6208
[2162,] 1316.7103 1277.8268 1222.8033 1401.4266 1196.4760 1381.7822
[2163,] 1274.6735 1243.5480 1193.6808 1345.7140 1175.8469 1338.8983
[2164,] 921.4048 912.0297 885.3053 949.6999 885.9534 1555.6020
[2165,] 532.3933 531.1791 523.1328 538.6979 525.7006 548.3772
[2166,] 1018.3305 996.2157 959.9455 1070.2448 948.1573 1205.2266
[2167,] 1292.1750 1245.1268 1187.5677 1389.9052 1152.3429 1728.2791
[2168,] 895.9099 905.7333 889.0142 893.5703 913.3840 1196.4010
[2169,] 5987.6341 6060.6221 6021.7545 5911.2687 6157.1250 5659.4670
[2170,] 1077.8713 1107.5424 1093.2000 1050.7171 1148.3661 1192.1858
[2171,] 1123.6617 1164.5687 1154.3373 1080.9331 1226.1143 826.9522
[2172,] 575.2107 678.3502 739.5955 463.5193 1015.6520 559.9195
[2173,] 741.5912 719.5022 694.4479 790.0115 677.8759 635.2225
[2174,] 2387.7296 2416.1340 2363.5498 2383.4766 2436.0934 2468.4109
[2175,] 1955.2567 1852.5807 1749.3076 2156.3965 1662.2822 1721.6511
[2176,] 545.9241 537.3509 525.4513 564.2077 519.2754 1042.9056
[2177,] 1628.4964 1664.7820 1636.0291 1600.9869 1709.0133 1725.9213
[2178,] 939.1589 880.9709 833.2178 1058.1748 783.5310 956.0699
[2179,] 1728.8420 1567.1088 1448.1994 2047.1763 1306.5251 1873.7047
[2180,] 1263.7422 1238.4110 1191.5454 1325.3595 1180.1626 1243.4827
[2181,] 681.4001 696.4533 691.7760 665.9105 720.1077 907.9942
[2182,] 760.9883 878.8837 930.1605 639.5344 1161.7904 1206.4828
[2183,] 1257.1525 1228.8427 1180.8530 1323.7213 1165.9061 1113.8689
[2184,] 980.4512 962.3663 930.0485 1025.0425 921.9375 1241.9542
[2185,] 1942.7829 1887.7017 1806.2107 2063.0775 1771.4197 1697.1459
[2186,] 934.8679 989.5669 994.4430 871.2671 1087.0609 818.4631
[2187,] 1494.6687 1397.7805 1312.5427 1689.0869 1226.2263 1277.8282
[2188,] 787.2459 806.4288 798.7484 768.5138 834.2001 1260.2948
[2189,] 850.0890 865.0468 852.8190 838.9095 882.9859 838.5137
[2190,] 1937.5785 1936.2581 1879.5761 1973.3318 1908.5429 2097.4765
[2191,] 701.3798 730.0914 730.9262 669.6147 780.0415 521.8419
[2192,] 1323.3451 1357.0767 1337.3674 1293.6881 1401.7272 1854.2135
[2193,] 836.0945 844.2755 829.0893 834.8817 850.0575 899.6447
[2194,] 1325.2891 1457.7945 1490.5376 1162.9893 1710.5809 1394.5776
[2195,] 644.3972 649.1424 641.1906 643.1837 652.9637 699.4882
[2196,] 1398.9434 1282.5911 1191.0647 1629.9537 1086.8950 1734.9345
[2197,] 1699.0117 1674.0018 1613.5668 1768.7381 1609.7138 1608.9116
[2198,] 1089.4792 1087.2726 1057.1712 1110.4906 1070.2074 1028.0614
[2199,] 1124.4286 1135.6303 1110.5958 1125.2750 1141.5785 831.4829
[2200,] 1932.6506 1824.9129 1719.6190 2143.7692 1627.1765 836.0776
[2201,] 731.7728 731.7549 717.2128 740.4489 725.1505 744.4960
[2202,] 1226.7333 1231.5025 1199.9488 1239.5436 1224.4742 1523.5438
[2203,] 1259.8459 1278.0440 1251.8294 1252.7622 1294.4807 1886.4859
[2204,] 1215.8149 1209.1335 1172.5264 1246.5041 1182.5084 1060.5096
[2205,] 1635.6274 1569.3695 1492.8519 1775.3894 1441.6266 2310.8227
[2206,] 3533.1033 3657.1079 3643.3618 3380.2921 3848.8321 3204.7197
[2207,] 984.0399 976.5170 948.5547 1011.0586 952.8159 1577.1264
[2208,] 436.8593 442.9363 440.2064 431.0224 451.2272 456.3196
[2209,] 914.7832 927.7703 912.0413 907.9924 940.8904 814.0948
[2210,] 1665.5859 1632.3398 1569.3734 1748.3618 1555.2694 1955.4265
[2211,] 881.0850 945.5478 957.8356 805.1008 1067.2570 1085.2401
[2212,] 1314.1063 1387.3836 1388.3101 1227.4866 1509.8912 1311.5055
[2213,] 1640.7299 1621.5678 1565.9301 1699.5917 1567.9337 1723.3783
[2214,] 690.2522 614.5390 574.2429 878.1595 512.9742 1459.9424
[2215,] 1198.1596 1191.8390 1155.9688 1227.9065 1166.0836 1057.1721
[2216,] 652.7977 672.0687 670.2287 632.9242 702.7042 743.6097
[2217,] 1193.2344 1176.5754 1136.0181 1239.6949 1133.5236 1314.5680
[2218,] 1314.1982 1319.9145 1286.3943 1326.7256 1313.6423 1097.6779
[2219,] 1058.2127 1094.0168 1083.5294 1022.2635 1147.3057 834.6153
[2220,] 1471.3493 1471.3298 1430.4640 1495.8200 1452.8163 1173.6034
[2221,] 1247.6992 1342.7413 1356.9444 1133.1915 1510.7968 1052.2568
[2222,] 1089.9793 1066.3160 1027.0028 1146.1454 1014.8495 1292.9209
[2223,] 1701.7981 1640.0722 1563.1302 1833.1006 1517.8343 1491.6214
[2224,] 740.4180 824.8453 855.7722 648.9998 1008.6298 1180.1828
[2225,] 1320.8179 1349.6547 1327.5981 1298.4121 1385.1603 1404.5996
[2226,] 1380.9429 1315.2529 1245.9419 1514.9145 1190.4210 1484.0450
[2227,] 1662.1748 1524.2024 1416.7687 1937.2597 1295.1003 687.5496
[2228,] 1990.2091 1997.8575 1944.7579 2011.3129 1986.1608 2067.3755
[2229,] 983.5865 974.1052 945.3604 1013.7669 947.3290 1173.1860
[2230,] 1010.4850 941.4173 886.3294 1152.3487 827.8209 1555.1093
[2231,] 827.8665 842.2687 830.4066 817.1507 859.4954 863.8747
[2232,] 834.6566 846.4061 833.0263 828.0192 858.6712 799.4223
[2233,] 1596.1863 1685.0218 1684.2426 1494.6826 1832.2136 1562.8534
[2234,] 953.1712 946.0754 919.4689 978.8128 923.3958 925.3490
[2235,] 2158.1202 2194.8036 2151.4208 2138.3931 2230.8182 2033.9042
[2236,] 684.6186 694.6968 687.4071 676.5208 708.0806 709.7252
[2237,] 1860.0181 2076.3109 2136.8493 1594.1546 2478.0232 1841.2643
[2238,] 723.2562 713.1704 694.2068 747.9507 690.1075 706.2526
[2239,] 890.5912 888.3577 866.4542 906.8682 875.0930 745.9900
[2240,] 1023.8381 1040.6752 1022.4716 1013.7905 1058.7566 726.6987
[2241,] 1150.9081 1224.3141 1230.1555 1064.5209 1350.3857 1245.3524
[2242,] 743.1235 700.3106 668.1585 833.3609 633.4502 710.8104
[2243,] 2605.3568 2494.3600 2370.6329 2824.3501 2275.1094 3165.8653
[2244,] 1484.8176 1567.3522 1567.4448 1389.3962 1705.9582 1699.9224
[2245,] 1177.5311 1245.1591 1246.9807 1098.9890 1358.1141 879.8824
[2246,] 909.0221 935.1981 926.2594 882.7823 973.3067 937.3516
[2247,] 995.4479 989.8435 961.9015 1019.5985 968.6760 1081.8697
[2248,] 1323.3060 1312.4338 1270.3097 1362.3416 1276.8027 1025.9639
[2249,] 878.9914 856.5387 825.5664 929.2715 810.0466 794.0927
[2250,] 1654.3550 1569.3428 1484.1171 1827.5458 1413.4468 2019.4387
[2251,] 513.7293 544.5660 553.7949 473.9118 601.7710 715.2583
[2252,] 1634.6769 1628.3483 1578.8809 1672.6442 1596.3790 1835.7349
[2253,] 454.7182 447.5979 437.9786 469.7888 432.7283 412.7576
[2254,] 771.2260 747.3287 721.3538 821.1505 703.6608 915.3167
[2255,] 1158.4575 1176.3965 1153.4924 1149.7718 1193.9602 586.5932
[2256,] 2076.7776 2050.5317 1980.0820 2153.9415 1979.7216 1708.8450
[2257,] 1755.6950 1765.0688 1718.6781 1771.5518 1758.3596 1535.9663
[2258,] 764.2913 756.7164 737.3812 786.2653 737.1650 803.7481
[2259,] 1114.3022 1156.9000 1147.8582 1069.0423 1221.9657 807.2052
[2260,] 2145.1679 2122.4196 2051.1968 2217.0250 2056.3110 1955.1018
[2261,] 1715.0875 1785.4470 1770.9601 1640.2267 1891.1820 1634.8998
[2262,] 985.2185 1021.5856 1014.4730 946.9708 1077.7541 954.3995
[2263,] 984.2544 955.2950 917.9553 1047.9132 897.6712 884.8851
[2264,] 356.7926 373.2088 377.7087 335.9261 403.4316 444.5782
[2265,] 1272.5059 1261.6346 1221.1229 1310.8493 1227.0420 1155.7352
[2266,] 806.7164 837.0622 834.0397 773.5247 885.4414 781.9307
[2267,] 1055.9044 1045.9737 1013.8635 1088.8354 1016.6135 866.3786
[2268,] 2198.0811 1523.3369 1227.3486 3678.7358 828.4161 910.3751
[2269,] 754.9724 756.9940 742.1498 761.5508 753.1350 810.1922
[2270,] 1325.5038 1329.3401 1294.7712 1341.1926 1319.5960 1682.2868
[2271,] 1340.7534 1338.3899 1300.5170 1366.5142 1317.6547 1284.0883
[2272,] 701.3195 712.8865 704.8564 692.2427 727.4047 571.6378
[2273,] 2541.7644 2460.1195 2350.2234 2715.4971 2287.2161 2427.9385
[2274,] 737.7370 807.6713 830.1071 659.9594 952.6782 755.8359
[2275,] 793.4151 738.9585 699.6971 905.1122 655.9417 839.5921
[2276,] 950.0049 992.9342 990.7463 902.2322 1063.8863 906.0687
[2277,] 1428.1112 1405.5016 1355.2233 1487.9271 1349.4206 1246.4523
[2278,] 991.5455 904.7427 843.8632 1173.3991 770.4020 1195.6200
[2279,] 2143.8916 2136.1643 2071.9914 2192.4805 2095.4233 1938.3937
[2280,] 915.6666 977.8043 987.7758 842.4177 1093.6073 875.9326
[2281,] 778.6537 803.4379 798.8667 751.7421 842.3427 855.3993
[2282,] 699.2283 705.2609 694.6894 698.0684 709.7275 754.3622
[2283,] 1188.3444 1178.4059 1141.1447 1223.7210 1146.6460 1131.0975
[2284,] 983.9577 935.2241 889.1292 1085.0971 848.7306 1085.1209
[2285,] 1136.5649 1137.4167 1106.9999 1153.6995 1124.9181 1248.3867
[2286,] 1037.0857 1028.5663 997.7242 1066.7947 1001.8568 1425.4615
[2287,] 909.5997 905.6030 881.8502 929.0223 888.7927 1089.2414
[2288,] 1214.2719 1213.5617 1179.8276 1235.4207 1197.1880 1307.5881
[2289,] 1480.3337 1462.9019 1413.3651 1532.9813 1414.4247 1573.5432
[2290,] 887.3971 940.8478 946.8717 825.0505 1036.9637 845.8470
[2291,] 1218.9199 1185.5489 1136.5136 1294.0686 1115.1461 1160.9251
[2292,] 1197.5224 1230.8502 1214.2869 1166.8707 1276.5090 1106.9418
[2293,] 348.9096 364.3647 368.5036 329.2968 392.5945 726.7781
[2294,] 294.2521 289.2850 284.0291 303.8239 279.9548 341.4539
[2295,] 637.6851 643.9109 636.8409 634.1406 650.3849 867.3818
[2296,] 1087.4844 1080.0402 1047.7785 1116.8294 1054.3315 1052.8620
[2297,] 936.4164 934.8675 911.4092 952.4361 921.8967 949.2620
[2298,] 499.9743 492.6066 482.0579 515.7553 476.8907 516.0234
[2299,] 1209.1695 1221.4891 1194.1725 1209.9748 1228.1308 1539.7652
[2300,] 517.2827 520.4256 514.8379 516.6645 522.7562 523.0876
[2301,] 2873.7875 2868.7581 2793.1511 2925.5377 2826.8879 3190.2898
[2302,] 1338.3012 1399.5375 1393.2954 1269.4042 1496.9104 1151.8795
[2303,] 852.4407 817.3303 782.4046 924.3757 753.5650 1023.5107
[2304,] 600.1337 627.5138 632.8464 566.9635 679.9152 549.5499
[2305,] 2198.3001 2158.7769 2077.9135 2295.5771 2063.9832 1887.6447
[2306,] 1806.6365 1752.8159 1675.1654 1925.5680 1639.4340 1880.7278
[2307,] 1714.4761 1694.1135 1635.2617 1776.8748 1637.2364 1741.7639
[2308,] 1010.2944 1071.5992 1076.7632 939.1521 1180.3723 817.2122
[2309,] 784.1669 792.1624 778.9526 782.0252 798.5710 752.9828
[2310,] 724.7595 776.3197 788.7354 666.0552 877.1865 548.3007
[2311,] 4141.2888 4268.2806 4258.2873 3981.5291 4463.8721 4397.9377
[2312,] 1143.8308 1186.6923 1176.7901 1098.6609 1251.6887 1056.9798
[2313,] 696.3742 690.6074 675.2012 714.4206 674.9924 825.3986
[2314,] 879.3102 899.6752 888.7777 861.2736 927.2481 1098.1559
[2315,] 1005.6095 1014.2154 992.5677 1007.6797 1017.6708 1131.4069
[2316,] 677.4894 667.2167 650.2718 701.5758 645.0175 986.4483
[2317,] 810.7848 797.0756 772.6833 844.6649 765.8369 873.6453
[2318,] 628.2183 634.6627 627.8930 624.2333 641.6214 699.6837
[2319,] 1303.1208 1338.8989 1320.9135 1269.4407 1387.7899 1099.7573
[2320,] 870.9953 876.1955 858.5403 874.9468 876.1897 948.5651
[2321,] 2442.5824 2447.2292 2382.3874 2473.5875 2425.8716 2218.4321
[2322,] 664.7829 784.7498 847.4671 550.8934 1117.5755 657.0933
[2323,] 607.3071 565.6030 537.6636 696.2312 497.7822 657.2871
[2324,] 645.0182 639.7308 626.7917 660.3224 625.9446 649.2837
[2325,] 1300.6168 1266.4577 1214.3253 1376.4081 1193.5079 1189.0949
[2326,] 1646.2750 1591.3285 1519.3886 1766.0345 1480.5323 1518.3078
[2327,] 1206.4947 1228.7104 1206.3170 1192.3291 1253.3922 984.2260
[2328,] 1122.1481 1123.7358 1094.1560 1137.8337 1112.7375 949.1498
[2329,] 557.8512 567.6923 564.7982 547.5847 581.9048 1559.9983
[2330,] 573.8703 596.8353 600.4880 545.4505 638.0615 621.7510
[2331,] 987.7211 1017.0401 1006.2508 959.0477 1059.1301 747.0429
[2332,] 689.4823 726.3343 732.1904 647.4238 795.7230 581.5071
[2333,] 567.1336 582.8612 582.8654 548.4097 608.6719 665.1824
[2334,] 1537.4132 1563.5409 1533.0864 1523.1052 1590.5812 1214.2705
[2335,] 689.8686 764.8511 793.9332 609.9075 934.3684 668.0511
[2336,] 643.9197 660.0254 657.2220 626.9375 685.9359 522.5887
[2337,] 1550.1011 1794.1621 1882.3917 1265.8917 2288.1807 1146.5557
[2338,] 626.2807 629.8343 621.6455 626.6797 631.6127 751.0176
[2339,] 849.7137 835.3572 809.0692 884.5926 802.5851 792.8315
[2340,] 1201.1341 1261.3545 1258.4262 1132.8910 1358.3490 1111.6569
[2341,] 873.0945 839.1130 803.3931 943.8586 775.9828 1203.8420
[2342,] 732.2230 771.1442 776.0701 687.7613 842.0298 895.6644
[2343,] 1192.1623 1193.3796 1161.2882 1209.8178 1180.6889 1202.8513
[2344,] 2730.3369 2639.9407 2523.3745 2916.3354 2453.9505 2694.1039
[2345,] 805.4478 824.6277 815.9339 787.6074 851.5076 1227.1395
[2346,] 834.4238 798.6680 763.9260 907.6175 734.8450 753.3786
[2347,] 1497.2377 1591.9821 1598.0920 1385.8840 1756.0673 1192.2648
[2348,] 1200.2140 1216.9507 1192.0894 1194.1337 1231.7085 1076.9065
[2349,] 469.6377 479.7570 478.5343 458.1371 495.2636 524.3590
[2350,] 1346.5311 1323.7037 1275.3981 1405.6694 1267.6510 1873.0713
[2351,] 1141.9332 1169.0475 1151.2343 1119.3324 1203.8474 1298.1626
[2352,] 917.9623 889.9755 855.5779 977.8988 835.2356 967.0582
[2353,] 832.8385 812.5578 784.8151 877.3867 771.4674 896.9423
[2354,] 701.1595 715.3165 708.6038 688.5613 734.6454 784.6598
[2355,] 1046.4644 1060.6604 1040.4225 1040.8080 1073.8158 1059.7669
[2356,] 882.6863 837.8818 797.3249 974.5193 759.1123 961.7910
[2357,] 580.2949 582.5428 575.3657 581.7237 582.7577 623.3960
[2358,] 560.4333 563.0179 556.3720 561.1270 563.9972 538.2927
[2359,] 607.4720 606.4184 596.9203 614.4345 600.5277 595.4119
[2360,] 1370.8289 1331.9912 1275.6085 1457.3934 1249.4583 1118.5146
[2361,] 2514.5711 2565.6245 2524.1359 2476.3767 2627.1991 2320.8484
[2362,] 1863.4783 1895.0917 1856.8755 1846.9576 1927.1649 1468.0012
[2363,] 650.1301 675.5680 677.1573 622.1301 720.2053 567.4541
[2364,] 560.4017 561.8033 554.5627 562.9214 560.6844 724.5399
[2365,] 712.3033 715.8309 703.5125 715.1768 715.6786 658.6678
[2366,] 1759.1243 1802.1227 1772.8963 1723.4655 1856.2995 2068.4409
[2367,] 1184.8043 1211.1337 1191.5228 1164.1089 1243.8198 1244.2880
[2368,] 1198.7389 1081.0443 999.3644 1433.6432 901.4274 1070.8577
[2369,] 1474.5277 1425.4797 1361.4751 1580.4200 1325.9959 1505.2334
[2370,] 793.1467 789.7261 770.7003 808.9147 775.9557 1125.0931
[2371,] 1138.3429 1144.9846 1117.2773 1146.4803 1142.6005 1106.0482
[2372,] 1457.5255 1458.8912 1419.0224 1479.5275 1442.9955 1399.8953
[2373,] 687.8033 687.2436 674.5712 696.0439 680.6643 1027.2026
[2374,] 1413.0233 1278.4790 1179.1998 1681.8523 1059.4726 1920.4146
[2375,] 716.5436 718.5929 705.4410 721.7685 715.7804 703.6409
[2376,] 659.0474 619.3437 592.0493 745.3791 557.3685 1217.9894
[2377,] 962.5546 939.6338 905.3775 1016.0289 890.8192 1000.3845
[2378,] 2996.0557 3004.8257 2934.9484 3026.0746 2986.9724 2807.3945
[2379,] 1121.2337 1207.3161 1221.0923 1019.6092 1361.5571 1501.5709
[2380,] 1071.9307 1120.7228 1116.3506 1018.5833 1199.0955 876.5071
[2381,] 964.8783 1041.7946 1057.0744 875.6334 1187.0797 936.0666
[2382,] 644.9248 652.8786 646.4355 638.9583 663.3299 757.2475
[2383,] 1679.8228 1694.0257 1652.6763 1686.5906 1697.1218 1710.1700
[2384,] 1287.4403 1373.7862 1382.4325 1183.1800 1523.7689 1482.9022
[2385,] 1014.0860 985.0040 946.2426 1078.0344 926.7837 909.5699
[2386,] 1323.7167 1371.7960 1359.3091 1272.9440 1443.9801 1552.0432
[2387,] 870.9291 894.0991 885.0017 848.4448 927.5688 935.9756
[2388,] 1010.5375 1060.9871 1060.3482 953.0404 1146.7567 1446.7589
[2389,] 926.3293 933.1794 914.0863 929.0732 935.0758 890.9847
[2390,] 562.6975 559.8507 550.4537 571.9017 551.3042 1347.0258
[2391,] 408.1899 402.8706 395.0397 419.9211 391.4057 363.6060
[2392,] 1441.5452 1400.3302 1341.1517 1532.6565 1314.2230 1475.9184
[2393,] 586.4521 576.5433 563.3142 607.6444 556.0423 589.2209
[2394,] 5250.6589 5236.8698 5139.1964 5326.2675 5171.8206 5267.9768
[2395,] 1994.4589 1859.0735 1740.1637 2253.2646 1620.2290 1865.8561
[2396,] 849.2064 749.6840 693.3022 1067.3758 621.5133 937.4910
[2397,] 551.3328 572.2422 575.3005 525.1843 608.4149 599.0601
[2398,] 807.5667 771.5061 737.8807 881.5303 708.6183 912.0287
[2399,] 1236.9122 1212.2596 1166.6100 1297.5641 1155.5116 1565.1480
[2400,] 802.3536 840.2241 841.3603 758.8593 904.6408 923.6046
[2401,] 748.0088 744.5433 727.9206 763.5403 731.7956 644.4134
[2402,] 428.3583 515.0860 561.3664 334.4836 752.5432 354.7765
[2403,] 642.3277 591.2680 559.4811 759.8502 513.1653 1169.3684
[2404,] 885.0786 857.2022 823.5958 945.2205 802.3984 778.6125
[2405,] 1461.1949 1439.7216 1388.6890 1520.1029 1384.5252 1161.1380
[2406,] 524.0909 510.0009 495.8319 551.4160 483.0632 558.8138
[2407,] 761.0811 729.1089 699.3354 828.0649 673.8635 651.2859
[2408,] 1260.7539 1236.1008 1189.6470 1321.2927 1178.9964 861.5253
[2409,] 647.8155 643.2563 630.6172 662.1694 630.6846 494.2160
[2410,] 865.0738 872.2610 855.7502 865.8705 875.8738 778.0520
[2411,] 843.4581 823.7526 795.6153 887.2833 783.0548 926.5331
[2412,] 1099.7723 1087.8889 1053.0077 1136.5618 1054.5319 1174.1229
[2413,] 625.0787 638.5033 635.3701 610.9492 659.0650 626.2518
[2414,] 506.7554 501.5941 492.0093 519.0771 489.4996 541.1937
[2415,] 760.2917 743.8885 721.2531 797.4052 710.9568 723.6214
[2416,] 1339.8736 1275.7855 1208.6286 1469.5550 1155.0123 876.3758
[2417,] 330.4393 326.1083 320.3157 339.5781 317.0402 680.1487
[2418,] 874.4520 774.4422 715.4124 1093.7663 640.6399 999.2154
[2419,] 842.3981 906.3929 920.3409 766.5671 1029.1087 836.8709
[2420,] 864.4350 863.2095 842.6277 878.3003 852.0331 1037.1148
[2421,] 994.3445 963.4681 925.1436 1060.9480 903.3112 889.4451
[2422,] 709.0718 696.1527 677.5202 738.3387 670.1076 767.0389
[2423,] 1168.9825 1211.7740 1200.9855 1124.2617 1276.2332 1366.5487
[2424,] 490.3981 510.2677 513.8766 465.1445 544.5164 460.3648
[2425,] 1129.0419 1153.7726 1135.2173 1109.6944 1184.3748 1339.4421
[2426,] 608.4956 624.0628 622.6166 591.3266 649.0346 649.7959
[2427,] 871.2966 875.7791 857.7649 876.3616 874.4978 847.9994
[2428,] 614.8112 623.1953 617.6813 608.2028 633.8248 658.1573
[2429,] 712.6289 728.9344 723.0312 696.3697 752.4621 717.4355
[2430,] 805.7507 774.7089 742.9553 870.2514 718.5997 836.9627
[2431,] 912.8279 1020.2008 1056.1365 789.5743 1247.6547 779.0296
[2432,] 2379.8837 2560.5113 2589.4474 2152.7080 2868.1178 3908.1058
[2433,] 449.5951 455.2610 452.0714 444.5327 462.6921 523.0657
[2434,] 802.3658 823.9262 816.5872 780.9868 855.5692 740.9549
[2435,] 693.2893 703.6060 695.4232 685.7573 716.4789 808.9017
[2436,] 1284.3726 1311.8765 1289.8341 1263.4503 1344.6206 944.7868
[2437,] 1232.1242 1345.0164 1369.4553 1095.5632 1552.6816 1157.7110
[2438,] 607.4451 576.8826 553.8502 670.3132 524.7612 925.7067
[2439,] 641.9256 644.1601 634.9985 644.5413 643.4518 747.0517
[2440,] 1384.0447 1383.2368 1344.6411 1408.2379 1364.5100 1089.6084
[2441,] 1026.4117 1053.5954 1040.4633 1001.1773 1091.6541 749.8139
[2442,] 1070.3400 1068.2772 1039.3408 1090.7386 1052.0671 1143.2994
[2443,] 1768.4705 1900.3210 1917.1924 1609.1871 2128.0873 1862.6220
[2444,] 736.3118 696.2820 665.6536 819.7686 633.4077 453.6929
[2445,] 637.2231 652.3807 649.8688 620.4557 677.9220 715.6756
[2446,] 648.7428 676.5067 679.4516 617.6249 726.6750 716.8524
[2447,] 1492.5219 1469.6090 1417.1697 1554.4508 1411.8615 1115.4568
[2448,] 785.5482 774.5363 752.1012 813.5231 748.0916 976.3492
[2449,] 650.7011 646.0894 633.3669 665.5054 633.4016 600.2808
[2450,] 991.3427 986.2789 958.8437 1014.5486 966.1186 1072.0765
[2451,] 1442.8871 1465.5297 1436.6373 1431.8066 1487.7708 1364.8487
[2452,] 530.4068 531.2364 524.2448 533.4967 529.3507 594.8371
[2453,] 852.2458 864.4194 850.7418 845.2634 877.2166 647.9610
[2454,] 750.9795 709.6479 677.2789 838.4861 643.1840 908.1583
[2455,] 1182.2125 1168.3661 1129.4903 1223.8065 1130.1715 1308.9986
[2456,] 920.5096 927.4569 908.5873 922.9999 929.6077 929.8187
[2457,] 865.1256 930.9686 944.8176 787.3413 1056.7783 919.9193
[2458,] 1161.9934 1181.9303 1159.9031 1150.3671 1203.1091 1273.6316
[2459,] 649.2694 680.5581 685.3541 613.9418 738.8055 859.8793
[2460,] 1028.1174 974.0955 924.7487 1138.8076 880.0691 789.7823
[2461,] 822.0393 774.5525 735.8586 918.7541 696.3315 1129.7283
[2462,] 1149.5530 1157.1443 1129.5134 1156.4498 1156.2658 1099.5207
[2463,] 1024.2434 1022.8428 995.7811 1042.2536 1008.4583 962.2330
[2464,] 1754.3420 1865.6478 1871.7973 1622.2917 2052.6373 1580.2623
[2465,] 1431.6005 1422.4351 1378.2648 1469.7400 1388.6739 1514.7840
[2466,] 895.9048 908.3444 892.9154 889.6087 920.7374 854.2770
[2467,] 800.7097 796.6639 777.1312 817.7923 781.7295 712.9935
[2468,] 485.5144 490.0244 485.6402 482.5181 495.0510 531.3309
[2469,] 960.0272 954.2778 928.1015 983.8242 933.7863 876.6200
[2470,] 1189.3833 1060.9082 975.9679 1448.1787 871.0527 952.9015
[2471,] 1200.5443 1186.2427 1146.5484 1243.2775 1147.0026 1785.5169
[2472,] 823.3611 819.0835 798.6600 841.3685 803.4818 874.7159
[2473,] 623.4891 537.4728 491.8803 861.8822 417.4508 1452.6512
[2474,] 570.4470 567.7451 558.2803 579.5027 559.3844 512.6812
[2475,] 548.0637 528.2212 510.9533 585.6079 492.1111 843.9215
[2476,] 716.3229 723.4152 712.7669 713.7962 729.5933 678.7139
[2477,] 630.0902 641.5288 637.2700 618.6606 658.2390 702.2004
[2478,] 751.9634 732.2785 708.0058 796.1399 693.4349 689.0187
[2479,] 351.5334 349.6443 344.6673 356.9225 344.5604 348.9848
[2480,] 602.4932 590.1015 575.3150 628.6692 565.5157 715.3991
[2481,] 1475.5145 1544.8610 1538.3972 1397.8152 1656.5278 1121.8980
[2482,] 859.3066 812.0406 771.9413 954.6229 732.3718 727.4885
[2483,] 1190.4145 1242.8362 1236.2401 1132.6390 1325.2670 1176.2988
[2484,] 1921.8295 1919.3485 1862.6867 1959.0783 1889.8912 1795.1724
[2485,] 857.2661 952.0755 983.5479 746.9995 1153.7506 682.1821
[2486,] 630.5092 688.8631 711.7478 565.0916 826.0532 653.8274
[2487,] 683.5604 679.3197 664.9421 697.6382 666.4344 708.6329
[2488,] 645.1965 639.8091 626.8176 660.7008 625.8512 529.9657
[2489,] 854.6665 820.6177 785.9822 924.7350 758.2631 863.8208
[2490,] 412.3348 416.0482 412.5791 409.7855 420.2502 423.3937
[2491,] 733.9098 736.9958 723.9247 737.7827 735.8176 682.5019
[2492,] 748.9957 740.6550 721.6863 772.9966 719.7112 1003.3090
[2493,] 1078.9991 1054.7876 1015.5169 1136.3044 1002.2867 1579.9613
[2494,] 1154.9220 1186.5341 1170.5588 1125.9803 1229.6209 1189.5860
[2495,] 1272.2913 1378.4933 1398.3117 1142.8439 1571.4163 1501.1626
[2496,] 643.8907 645.0301 635.2829 648.2276 642.3709 598.5240
[2497,] 899.1489 908.2025 891.0078 898.0376 914.4214 954.0635
[2498,] 909.5751 883.9120 850.9344 964.9453 832.9768 910.1550
[2499,] 815.8137 811.3185 791.2217 834.0733 795.6493 975.0394
[2500,] 1158.7274 1154.0471 1120.2608 1185.0597 1131.6836 1405.8134
[2501,] 480.0862 473.8047 464.1057 493.9825 460.0439 732.1877
[2502,] 2041.0415 1840.0846 1691.4780 2425.2413 1511.5719 2218.8460
[2503,] 545.9460 550.7930 545.5583 543.0273 555.9561 551.9969
[2504,] 1369.3126 1316.9033 1253.9704 1479.4360 1212.5669 1436.5989
[2505,] 1011.9323 1055.3406 1050.9773 963.6462 1126.2412 1078.6819
[2506,] 1623.7035 1628.0388 1583.9891 1644.5742 1614.6503 1740.4561
[2507,] 560.4555 548.8183 535.1898 583.9880 525.5884 625.5582
[2508,] 1082.1339 1030.5232 979.0225 1189.0960 937.2955 1082.3844
[2509,] 675.3504 671.4016 657.3498 688.7876 659.0992 631.0543
[2510,] 905.2007 932.6884 924.5354 877.1802 973.3826 1009.0594
[2511,] 630.1130 650.9635 651.6119 605.7310 688.7280 564.6742
[2512,] 1312.3729 1400.0550 1408.7276 1206.3509 1552.6326 1605.1151
[2513,] 1847.3958 1842.1148 1786.7985 1887.4846 1809.0608 2011.7190
[2514,] 553.1556 553.8883 546.4469 556.6373 551.6485 656.1288
[2515,] 765.6825 738.4663 710.8998 822.6718 689.6339 611.3559
[2516,] 423.9803 446.9178 453.4775 394.8492 488.8693 439.8747
[2517,] 762.0783 806.5422 812.8822 711.0475 887.2974 1340.2778
[2518,] 1722.1746 1733.5204 1689.2807 1734.2527 1730.8460 1832.8498
[2519,] 772.1953 767.4237 748.3220 789.7800 751.6043 912.7373
[2520,] 621.1789 621.4857 611.9769 626.5443 617.5688 893.2625
[2521,] 741.1363 724.0843 701.1720 780.1539 689.4829 976.1022
[2522,] 846.2893 791.4198 748.2468 957.5382 702.9937 891.8882
[2523,] 928.2532 921.5023 895.8117 952.4261 899.7508 1046.4572
[2524,] 654.9932 686.5589 691.1920 619.4537 745.1645 614.6995
[2525,] 1613.6583 1639.4013 1606.0034 1601.5127 1664.4186 1097.9036
[2526,] 524.1260 514.6999 502.7786 543.6111 495.3814 608.4819
[2527,] 828.4796 838.7678 824.8410 823.9422 848.4580 574.7724
[2528,] 634.8479 632.4790 621.1741 644.5796 623.7850 1195.8481
[2529,] 3737.2738 3662.8609 3545.8605 3897.8976 3498.0843 3892.0825
[2530,] 1004.5855 1043.0623 1036.3949 963.0575 1103.6943 1158.8441
[2531,] 526.7705 533.9522 530.2486 520.1480 543.5240 979.2460
[2532,] 1073.7506 1093.7190 1074.6852 1060.4908 1116.4251 1665.9086
[2533,] 813.8484 854.9908 857.3366 766.5889 925.8219 921.3506
[2534,] 897.4772 915.8324 903.2994 882.4449 939.0997 678.5429
[2535,] 582.2766 589.1758 584.1465 576.8562 597.6677 669.4065
[2536,] 595.6831 564.8122 541.7529 657.4581 512.0642 837.2289
[2537,] 576.2370 515.5415 480.0690 710.9553 423.5684 486.5530
[2538,] 398.2408 392.5247 384.7648 410.3599 380.6570 382.6474
[2539,] 1001.9680 972.5320 934.4515 1066.0109 914.4211 1137.5456
[2540,] 607.3811 604.8290 594.5896 616.8333 596.3417 638.7007
[2541,] 827.7180 876.4373 882.4210 770.4162 963.9200 823.8692
[2542,] 714.8262 757.6935 766.0510 665.4537 840.2470 738.3892
[2543,] 634.7039 706.7860 738.4058 556.8555 886.0612 913.2068
[2544,] 718.0432 690.7135 665.5098 775.1008 643.7247 642.9423
[2545,] 1117.1656 1155.4651 1144.1317 1078.0077 1212.0794 914.5117
[2546,] 649.7669 666.7171 663.8802 632.5874 692.9652 837.2552
[2547,] 566.0129 561.1547 550.7068 578.4616 549.1425 615.6595
[2548,] 524.0482 527.4409 521.8561 523.1226 530.1615 555.3216
[2549,] 1500.6567 1422.6601 1345.0568 1659.5070 1278.6134 1948.6828
[2550,] 861.6999 1018.8339 1090.5824 696.2655 1400.6513 655.1162
[2551,] 594.5733 617.4986 620.7504 566.5881 659.6648 585.7534
[2552,] 1371.8441 1329.9387 1272.0533 1463.6737 1242.4173 1170.2969
[2553,] 2147.2815 2299.1149 2317.1863 1961.4400 2556.5427 1975.4280
[2554,] 872.6343 889.0422 876.6789 859.8726 909.6830 786.8499
[2555,] 1078.6882 1080.0938 1052.1991 1093.7825 1069.4413 987.1740
[2556,] 630.6288 593.2545 567.1100 710.9122 532.5957 813.6817
[2557,] 857.1543 864.1839 847.8246 858.0573 867.6204 1046.0187
[2558,] 2248.1964 2197.8532 2109.3382 2367.3408 2081.2925 2220.9433
[2559,] 800.6349 794.7479 774.3352 820.7649 776.6797 778.3036
[2560,] 663.6885 665.9551 655.2186 667.2003 664.5779 681.7488
[2561,] 529.8952 541.1402 539.4831 517.3019 558.2504 675.0413
[2562,] 1155.3206 1146.3103 1110.6069 1188.5337 1116.6554 1196.4708
[2563,] 445.9661 453.3948 451.1877 438.2253 464.1483 736.7206
[2564,] 664.8642 644.2328 624.1862 708.2979 607.6868 772.0618
[2565,] 1522.7621 1681.6800 1722.3132 1332.4291 1984.8577 1380.3069
[2566,] 799.0781 830.0441 827.7107 764.5851 880.2676 1212.9180
[2567,] 749.1856 765.5713 757.5209 735.0559 787.8667 806.7138
[2568,] 718.8245 661.6031 626.0830 844.8828 580.9334 775.9956
[2569,] 942.9781 876.5857 825.3212 1079.6769 768.4568 829.8850
[2570,] 771.4482 746.6870 720.3174 823.0346 701.6875 871.4029
[2571,] 700.6860 728.0325 728.1642 670.7141 774.8583 768.3992
[2572,] 585.7698 610.2026 614.3147 555.6333 655.3215 575.4083
[2573,] 1347.8306 1363.2185 1333.6343 1346.1684 1373.6257 1371.5523
[2574,] 751.6957 754.7771 740.6606 756.5753 752.8246 792.2354
[2575,] 1213.7748 1235.6374 1212.8183 1200.2782 1259.5467 1448.7364
[2576,] 598.1917 585.1671 570.2652 625.1503 559.7148 528.7669
[2577,] 1204.8574 1169.1582 1119.5449 1283.7520 1095.3520 1523.7775
[2578,] 956.0392 980.2104 968.0766 934.1721 1013.8461 936.9393
[2579,] 743.5775 733.7659 714.2058 769.7707 710.3473 851.3991
[2580,] 626.5960 647.7697 648.6617 601.9808 685.9219 877.9173
[2581,] 687.2225 702.0533 696.4965 672.7407 724.3707 613.6078
[2582,] 919.5193 925.3953 906.0334 923.6400 925.6543 828.4493
[2583,] 951.2016 939.0254 910.0869 985.3179 907.8612 889.6706
[2584,] 650.8202 638.6163 622.2197 679.4052 613.3426 910.6725
[2585,] 539.2291 529.6663 517.4151 559.0720 510.0263 500.2435
[2586,] 1541.2124 1592.1359 1573.8784 1490.8062 1665.9257 1544.3707
[2587,] 767.1864 777.4816 765.8783 761.2968 788.2759 694.6194
[2588,] 1740.6152 1730.9384 1676.1048 1786.0136 1691.5512 1561.6867
[2589,] 879.3966 889.0550 873.1406 876.8767 896.8920 909.9466
[2590,] 749.8228 704.5871 671.0307 845.8584 634.2020 992.7953
[2591,] 3038.8212 3036.1647 2960.3961 3087.5434 2997.8136 3316.7208
[2592,] 1395.5071 1386.5698 1343.7517 1432.9043 1353.7634 1475.4335
[2593,] 633.6149 608.9066 588.2001 684.7930 566.4817 695.3507
[2594,] 2047.9797 2063.1212 2013.1710 2058.6739 2063.7290 1963.8988
[2595,] 955.9678 1010.3356 1013.8575 893.7624 1105.3251 1038.2927
[2596,] 575.4283 596.8106 599.5646 549.2109 634.5503 516.8802
[2597,] 618.2074 639.1312 640.0639 594.3769 675.8710 838.8026
[2598,] 1220.9430 1208.5178 1169.0455 1261.0266 1172.1338 626.9015
[2599,] 986.6408 993.7338 971.9586 990.6750 994.7727 955.1164
[2600,] 770.8763 774.4348 759.4024 775.3261 773.0884 685.1341
[2601,] 529.5201 510.5226 493.9459 565.3896 475.8086 506.7551
[2602,] 606.1756 618.8914 616.0942 592.6385 638.7741 643.0011
[2603,] 588.8701 574.1211 558.5552 618.5074 545.8114 469.5182
[2604,] 764.3067 752.3449 731.4126 793.4579 726.3576 812.0747
[2605,] 701.6944 702.3653 689.5255 708.8494 697.2995 773.7389
[2606,] 937.3595 931.6202 906.1348 960.0713 911.4589 880.9042
[2607,] 536.2211 541.5918 536.7952 532.4104 547.7789 556.9153
[2608,] 655.3170 684.3707 687.6450 622.8466 737.1658 765.6092
[2609,] 499.7737 490.8109 479.4935 518.1593 472.4554 902.7282
[2610,] 727.2643 724.4429 708.6466 740.2967 713.0352 700.8518
[2611,] 851.3257 815.7508 780.7068 924.0743 751.3773 917.7297
[2612,] 568.1718 568.2180 560.1605 572.8808 564.6513 595.2785
[2613,] 1914.7733 1740.4814 1607.7749 2249.4952 1454.2344 2156.9369
[2614,] 1239.1053 1397.3008 1447.6950 1049.5752 1714.1452 868.5614
[2615,] 991.8642 976.9087 945.3483 1031.1705 941.1583 1026.8168
[2616,] 476.6054 442.7707 420.6854 539.6764 388.5950 499.0791
[2617,] 791.2522 781.5865 759.6323 817.2360 757.2833 740.9405
[2618,] 802.5596 905.8215 944.9155 688.3536 1136.2580 750.3950
[2619,] 2815.1198 2792.9148 2711.0235 2893.2167 2722.5952 2602.7109
[2620,] 336.8940 326.8919 318.2893 355.8987 308.7846 486.5704
[2621,] 513.4856 475.0395 449.9761 585.7073 412.9588 495.2228
[2622,] 1680.7108 1634.0115 1564.4622 1786.5068 1535.3236 949.2511
[2623,] 830.4335 833.6772 816.2350 836.7174 830.7448 624.3582
[2624,] 872.3214 854.1794 825.3848 914.7613 814.6208 768.2855
[2625,] 1048.0835 1102.7078 1102.4537 986.2764 1194.4272 907.4495
[2626,] 595.8790 584.1318 569.8918 620.3657 560.7587 652.7719
[2627,] 588.6981 564.7161 544.8429 635.9201 522.0363 533.3973
[2628,] 702.0079 697.1973 682.2932 717.8425 683.7782 610.0911
[2629,] 1271.5150 1313.4208 1299.1021 1229.4322 1373.0250 1180.6243
[2630,] 1034.1891 1090.3276 1091.5598 969.7301 1186.2964 1089.4082
[2631,] 1174.7481 1195.5833 1173.6037 1161.9883 1218.2523 1199.3303
[2632,] 810.0673 825.6838 814.9761 797.5886 845.5277 932.3961
[2633,] 1291.3660 1386.5272 1399.8698 1175.4709 1555.4555 1274.0165
[2634,] 540.5944 521.9827 505.4240 575.8521 487.8308 630.8997
[2635,] 725.0673 762.6154 767.3296 681.9756 831.6356 685.1703
[2636,] 405.2301 386.9751 373.3273 439.7340 355.9803 449.7119
[2637,] 384.5467 389.4215 387.1770 379.8892 396.1432 355.1332
[2638,] 654.8147 692.3173 700.4766 612.2830 766.4081 599.3658
[2639,] 814.3525 824.0711 810.3217 810.4902 832.9188 751.5805
[2640,] 608.3672 652.3013 667.8606 555.9227 750.3187 561.9758
[2641,] 440.6200 438.7514 431.9374 447.0319 432.8453 579.4811
[2642,] 692.8679 679.1664 660.0399 724.7153 650.5737 879.4867
[2643,] 658.4083 700.8997 712.1603 610.1953 788.0418 553.0603
[2644,] 1176.5354 1147.7508 1102.2393 1242.9147 1085.4063 1445.0687
[2645,] 629.3311 657.4980 662.2620 596.1619 711.7960 575.0807
[2646,] 1770.5217 1873.8960 1875.4531 1648.7389 2044.9070 1668.9972
[2647,] 797.2330 787.0704 764.7181 824.3632 761.8636 794.9209
[2648,] 1866.1011 1786.5662 1695.1030 2030.1036 1631.2105 1314.5574
[2649,] 594.5613 582.7387 568.5158 619.0760 559.2851 526.7944
[2650,] 506.6307 505.2365 497.5473 512.9479 499.6516 490.8212
[2651,] 1107.2482 1117.7519 1092.9597 1108.8187 1122.7191 1090.9882
[2652,] 1022.9993 967.5236 917.9768 1136.2948 872.0505 953.1311
[2653,] 605.5049 593.6323 578.9603 631.0015 569.7751 838.2331
[2654,] 598.3724 625.0048 630.0354 566.0037 675.7197 845.6455
[2655,] 777.5507 745.7674 716.2755 842.4420 691.0849 801.8512
[2656,] 471.1942 440.5907 420.0063 528.0507 390.8017 716.1763
[2657,] 737.0405 688.5325 654.2035 840.4389 615.4865 564.3155
[2658,] 446.3202 449.5570 445.2149 444.8602 452.6168 425.4308
[2659,] 517.6975 471.7597 443.4854 605.7262 400.2258 553.6470
[2660,] 515.8101 500.8222 486.3195 544.5918 472.4804 701.8359
[2661,] 835.6046 802.3067 768.6461 904.0594 741.6694 811.6044
[2662,] 678.9812 682.1563 671.5286 681.2916 682.2321 634.5026
[2663,] 731.0539 667.5430 629.2322 872.5595 579.9291 571.0788
[2664,] 568.1972 568.5022 560.5737 572.5026 565.3894 509.3986
[2665,] 574.2076 572.5377 563.5180 581.6716 565.9310 692.5019
[2666,] 838.1254 876.1087 876.0507 794.5305 940.4221 946.0606
[2667,] 808.3412 812.8929 797.2753 811.9143 812.7772 855.9506
[2668,] 934.7325 945.5295 928.1148 931.6008 954.3891 936.0221
[2669,] 921.5272 904.9008 875.0476 961.7614 867.3241 795.8483
[2670,] 1275.1801 1196.5151 1125.9457 1430.0343 1058.2685 1123.8626
[2671,] 1038.9700 1031.8031 1001.5368 1066.5257 1007.3497 731.0344
[2672,] 622.4674 635.5766 632.3330 608.9113 655.1907 605.1056
[2673,] 833.7018 802.4453 769.7221 898.3119 744.6010 871.8163
[2674,] 943.6453 1002.3549 1008.8974 875.4191 1107.9791 999.3065
[2675,] 514.8271 510.8927 501.8113 525.2605 500.8715 535.7401
[2676,] 1493.4896 1467.7051 1413.8767 1560.2124 1405.1710 1505.3586
[2677,] 552.6597 570.2879 571.5688 531.1129 599.7795 618.6116
[2678,] 847.6165 811.3808 776.2690 921.4685 746.3640 810.7139
[2679,] 2248.8706 1755.9258 1496.7668 3239.1158 1125.6759 1551.1679
[2680,] 1748.1945 1819.0085 1804.1577 1672.0628 1926.5440 1889.0988
[2681,] 914.4315 899.5523 870.8432 951.6372 864.9987 867.0205
[2682,] 664.2370 673.5957 666.4019 656.9556 684.9780 650.8349
[2683,] 378.2717 379.5391 375.5478 379.0417 379.6868 485.0586
[2684,] 931.0277 983.0641 986.7279 870.5900 1075.0385 979.3504
[2685,] 902.8148 810.4397 751.4257 1100.1760 678.9083 1134.3360
[2686,] 552.4865 577.7354 583.1364 520.4063 623.5441 471.3941
[2687,] 605.4125 594.8337 580.7463 628.6025 573.0301 709.7532
[2688,] 1032.5775 1097.4506 1103.4193 957.2046 1211.9389 1433.4111
[2689,] 1525.5578 1600.6809 1595.3922 1441.2806 1722.9849 1338.5375
[2690,] 490.1380 481.9439 471.1598 507.2148 464.9287 538.0415
[2691,] 1164.0781 1176.6817 1150.9854 1163.5736 1184.5107 1289.0682
[2692,] 1196.0620 1168.6157 1123.0224 1260.6134 1108.0018 897.3445
[2693,] 412.4850 404.3584 395.1235 428.8727 388.3487 477.8948
[2694,] 1143.9986 913.5858 802.1531 1694.0016 654.0980 984.1518
[2695,] 559.2268 548.3039 535.0394 581.5221 526.2483 530.4459
[2696,] 745.5702 786.8255 792.0109 698.9998 860.6600 1045.6315
[2697,] 727.1238 711.8237 690.6100 761.5352 680.9417 737.1775
[2698,] 1942.2219 1929.3096 1867.0321 1995.6306 1881.7330 1644.7187
[2699,] 989.2090 974.2285 942.8376 1028.5073 938.5755 1180.0678
[2700,] 527.4305 525.1611 516.6857 535.3483 517.9028 586.6907
[2701,] 1063.7038 1060.1682 1030.8200 1086.4423 1041.5351 1519.9133
[2702,] 422.8846 411.3509 400.3474 445.1481 389.9128 392.9888
[2703,] 603.7475 613.0005 608.7792 594.9109 626.3753 587.1901
[2704,] 528.7073 537.1414 534.0481 520.2378 549.0054 935.8754
[2705,] 887.7338 908.6063 897.6334 869.2215 936.7354 1073.7373
[2706,] 516.1420 490.0625 470.4115 564.6076 444.8155 578.8560
[2707,] 768.1516 771.8420 756.9483 772.3534 770.7628 742.4039
[2708,] 975.2549 985.7306 965.9981 973.8970 992.9888 908.2309
[2709,] 536.1202 532.3163 522.9221 546.5671 522.3468 519.4517
[2710,] 532.6824 538.7203 534.3265 527.8293 546.1497 530.5004
[2711,] 340.8477 403.6282 438.8783 276.1734 563.5216 401.9871
[2712,] 666.3150 703.1425 710.6950 624.0369 775.4567 775.4197
[2713,] 820.6249 814.2835 793.1366 841.8966 795.4772 759.8789
[2714,] 541.4698 570.6472 578.4033 504.0838 624.9142 540.5394
[2715,] 4836.3358 5012.8571 5019.1797 4624.3247 5296.8649 5553.8203
[2716,] 601.5807 601.2322 592.1933 607.3734 596.6202 669.9563
[2717,] 453.7084 467.6572 468.7180 436.6763 490.6302 907.2133
[2718,] 717.1088 702.7755 682.9133 748.7826 674.1472 856.2598
[2719,] 922.4050 938.3157 923.8050 911.3701 956.6835 970.6394
[2720,] 681.0447 666.9292 648.2916 712.4272 639.0271 708.1398
[2721,] 381.5961 386.7513 384.6972 376.4938 393.9683 385.2090
[2722,] 831.3132 852.0577 843.2895 811.3462 881.0888 790.5059
[2723,] 826.3685 830.1305 813.0570 831.7796 828.1654 669.9970
[2724,] 954.8811 955.4991 932.5216 967.8629 946.0299 1009.9208
[2725,] 1208.7680 1204.2177 1168.8455 1235.9011 1181.3322 499.9074
[2726,] 604.1926 614.6319 611.0128 593.6003 630.4727 886.3869
[2727,] 846.4202 835.8741 811.3882 874.9549 809.2122 783.8989
[2728,] 631.7251 631.4159 621.1913 638.1780 626.3266 665.5197
[2729,] 619.4529 626.9759 620.9285 613.8136 635.9783 542.5674
[2730,] 674.9287 644.2271 619.8172 738.9449 594.5161 755.7567
[2731,] 811.7747 730.0704 681.0949 988.6993 619.6692 705.4576
[2732,] 892.7184 944.3427 949.2129 832.6226 1036.4399 768.4134
[2733,] 595.6328 585.6438 572.2048 616.9829 565.0702 582.3252
[2734,] 941.2998 934.9841 909.1064 965.0083 913.7901 924.3286
[2735,] 1093.0759 1106.3358 1083.3607 1090.1668 1116.4808 1242.7042
[2736,] 917.4331 902.7211 873.9126 954.4143 868.3058 883.9772
[2737,] 533.3704 542.7293 540.0314 523.5715 556.2734 572.4763
[2738,] 517.5136 527.0649 524.7519 507.2789 541.1231 639.0776
[2739,] 496.2927 500.9325 496.4468 493.1881 506.0988 600.7092
[2740,] 1203.5719 1176.7113 1131.1254 1267.2967 1116.8922 1671.2608
[2741,] 729.7275 713.1876 691.2728 766.6603 680.3242 741.3082
[2742,] 710.9542 718.2576 707.8476 708.0295 724.8789 724.2588
[2743,] 784.8684 770.1901 746.2279 819.0863 738.5137 746.1716
[2744,] 627.9698 673.1438 687.4446 575.9324 770.9777 584.1174
[2745,] 610.4188 574.4973 549.0484 686.0539 514.7270 1024.1258
[2746,] 672.7981 676.7862 666.7019 673.7749 678.3713 676.8636
[2747,] 627.7146 643.5012 641.5409 610.2298 669.5547 1082.1589
[2748,] 445.0672 430.7970 418.0447 472.1857 404.8139 430.9462
[2749,] 3943.4494 4034.6458 4001.6035 3852.3379 4158.8904 3586.1676
[2750,] 658.5362 662.4366 652.6276 659.4598 664.0115 738.3445
[2751,] 472.4746 466.0657 456.4426 486.4833 452.1803 513.3083
[2752,] 476.2124 502.6942 510.1415 442.0501 550.6144 458.7689
[2753,] 724.5387 733.9101 724.1977 718.6832 744.1252 1103.8676
[2754,] 471.0307 446.4390 428.4262 516.5150 404.7756 853.6947
[2755,] 546.2387 553.7296 549.8384 539.3426 563.7113 575.1922
[2756,] 713.2875 711.2809 696.2716 724.8229 701.4333 661.3358
[2757,] 670.8518 741.1545 769.0763 595.2153 903.8191 589.0309
[2758,] 761.1793 761.5551 745.4704 770.4290 754.7401 595.0064
[2759,] 532.9333 550.6268 552.3122 511.1284 580.1296 703.3995
[2760,] 495.8269 508.9080 508.8162 480.1937 529.8105 565.9384
[2761,] 616.8673 554.2354 517.5473 768.5682 459.6734 561.7847
[2762,] 546.9306 533.1408 518.7274 573.9365 506.5696 465.8887
[2763,] 488.5191 520.3219 530.5597 447.3265 579.6144 524.5783
[2764,] 553.0821 567.3242 566.8093 536.3646 590.0542 541.7268
[2765,] 602.0627 573.6578 551.6470 659.2681 524.6129 625.4683
[2766,] 399.6824 403.6312 400.5785 396.6069 408.3975 424.3499
[2767,] 875.6412 848.0920 814.8965 934.8255 794.1812 854.0733
[2768,] 606.8066 613.8159 608.3893 601.3612 622.8124 670.9787
[2769,] 757.2525 690.9727 649.9249 902.2244 599.5260 927.5241
[2770,] 529.8714 532.5545 526.5051 530.0926 533.9588 483.8316
[2771,] 624.0395 629.0154 621.5869 622.2366 633.3618 563.2870
[2772,] 1198.6573 1246.1599 1236.7402 1147.8621 1318.7989 1185.6850
[2773,] 520.9218 476.7871 449.1569 605.1875 407.1804 887.4210
[2774,] 572.2567 574.2586 567.1092 573.9723 574.1070 517.1488
[2775,] 1315.6270 1311.8399 1273.3887 1343.1336 1288.6910 1224.9327
[2776,] 691.1170 718.4570 719.1004 660.6902 765.6874 650.3988
[2777,] 888.8391 917.7041 910.7583 859.1108 961.0854 1076.5465
[2778,] 586.2632 598.3047 595.8487 573.3276 616.3790 443.6461
[2779,] 527.4506 523.6258 514.3821 537.8439 513.6985 573.6073
[2780,] 737.1317 738.2919 724.1938 744.0444 733.6865 694.4929
[2781,] 1160.2572 1133.9300 1090.0857 1222.1767 1075.7801 963.8006
[2782,] 869.1433 885.0354 872.6856 856.9219 904.9564 842.9329
[2783,] 543.4142 534.8026 522.9306 561.7335 516.6885 914.3098
[2784,] 432.6570 434.1844 429.2052 433.6853 434.2850 417.0034
[2785,] 474.1363 472.6526 465.4271 480.2829 467.1389 469.0000
[2786,] 847.3817 833.3532 807.3437 881.6675 801.1971 841.1852
[2787,] 648.0359 672.9695 674.4645 620.3546 716.8063 660.7052
[2788,] 1196.8565 1258.2815 1256.1374 1126.9138 1357.8673 1023.4377
[2789,] 731.5857 718.2151 697.2663 762.9448 689.6799 694.6604
[2790,] 410.8895 408.2203 401.6695 418.2681 401.2838 403.4874
[2791,] 1736.6626 1734.3317 1683.0823 1770.4668 1707.5572 1763.0772
[2792,] 850.3631 898.0053 902.6340 794.4408 982.6411 721.4950
[2793,] 551.6788 559.1803 555.1916 544.8304 569.1231 606.3587
[2794,] 698.3939 678.6044 656.5586 741.6987 641.3696 734.0403
[2795,] 573.9097 595.7443 598.7880 547.0216 634.4637 572.7207
[2796,] 1028.1322 1037.2185 1015.0793 1029.8953 1041.1973 915.8140
[2797,] 1234.1514 1197.2327 1146.1077 1315.3151 1121.0276 1462.7678
[2798,] 740.0781 706.3654 677.5182 810.8081 649.6326 697.7011
[2799,] 384.4594 398.1869 400.5764 367.3694 422.0868 484.1126
[2800,] 569.5516 619.2525 639.2312 507.6550 735.5500 584.8268
[2801,] 403.4962 397.1171 388.8724 416.8621 384.0421 475.3353
[2802,] 406.3005 395.1926 384.7057 427.7967 374.6019 565.4932
[2803,] 426.8940 421.0229 412.5292 439.6851 408.4599 497.2130
[2804,] 1057.9164 1013.2861 965.4534 1152.0790 930.4082 1039.2218
[2805,] 1460.1364 1486.8593 1459.4039 1443.3930 1516.3002 1384.6331
[2806,] 516.6970 568.8173 590.4995 450.6777 684.0791 917.4875
[2807,] 477.2558 487.1341 485.6594 466.1679 502.1184 560.9255
[2808,] 1098.3227 1178.5973 1190.0211 1004.2566 1321.8605 1132.8251
[2809,] 555.8806 646.2605 697.5362 452.0116 932.3387 520.7592
[2810,] 880.9398 799.5886 745.2928 1052.3972 680.3755 1405.6489
[2811,] 771.9981 751.4942 726.7507 815.7549 712.6755 1042.6264
[2812,] 641.4622 645.6790 637.5202 641.0224 648.5033 725.4107
[2813,] 971.1642 990.5251 975.2719 956.7964 1014.0907 873.6397
[2814,] 385.7856 392.9177 391.7781 377.8579 403.8217 413.5635
[2815,] 489.9214 484.7607 475.4657 502.0795 472.8356 570.4796
[2816,] 2228.1848 2112.7710 1996.8512 2454.7798 1895.6644 1812.4568
[2817,] 654.2052 666.6034 661.1822 643.2386 683.7140 724.9382
[2818,] 604.9464 620.3399 619.0063 587.6404 645.4858 651.8796
[2819,] 1208.9186 1193.7226 1153.3430 1253.2892 1152.8789 568.6048
[2820,] 665.2602 662.4546 649.4767 676.7445 652.2162 1007.7886
[2821,] 1094.8018 1098.3259 1070.5903 1106.9048 1091.1268 1114.6288
[2822,] 362.0668 386.6836 395.7746 331.1189 435.2630 400.8112
[2823,] 516.3319 534.2634 536.3836 494.0346 564.4318 529.6886
[2824,] 623.4759 661.4798 672.1291 578.8853 740.3644 518.2495
[2825,] 567.4060 556.0185 542.3840 590.7267 533.1343 761.6801
[2826,] 860.0798 863.7884 845.7212 866.1500 861.2878 1139.5593
[2827,] 647.6897 644.9355 633.1848 658.8385 635.4607 893.6614
[2828,] 648.7197 653.5733 645.3834 647.6005 657.6241 650.7140
[2829,] 1283.3913 1292.9340 1261.7072 1289.9802 1293.4336 1298.8918
[2830,] 570.5509 540.8325 518.6425 627.8120 489.6876 581.2953
[2831,] 935.6666 959.0878 947.9337 913.8010 992.2615 852.0124
[2832,] 701.0890 672.2554 646.6906 762.4577 623.2364 1062.1163
[2833,] 420.2454 421.9125 417.2741 420.8987 422.3846 469.1174
[2834,] 633.1314 636.5322 628.1301 633.8456 637.9755 592.1071
[2835,] 427.3967 433.5852 431.0833 421.3434 442.1997 504.5974
[2836,] 609.3711 614.3797 607.8887 606.9819 619.5120 756.0371
[2837,] 700.1910 727.9401 728.2967 669.7350 775.6373 913.8071
[2838,] 580.2987 577.2162 567.3880 590.2329 568.1207 465.1875
[2839,] 408.0671 393.1282 380.8792 436.4521 366.8161 489.5000
[2840,] 923.0612 939.1461 924.7020 911.7783 957.8251 1104.9431
[2841,] 619.5865 631.6916 627.9877 607.5645 649.1572 738.5257
[2842,] 475.0408 491.1125 492.9434 455.0300 517.9371 451.8328
[2843,] 629.3046 646.5494 645.3180 609.7680 676.0295 606.5109
[2844,] 561.6585 543.0268 526.0657 597.4262 508.6718 511.3673
[2845,] 533.4781 511.7738 493.8758 574.1705 472.8672 457.8458
[2846,] 634.5576 701.6029 730.1787 561.1260 865.3991 511.9416
[2847,] 575.3463 592.3196 592.7313 555.2005 620.4740 569.3180
[2848,] 486.5512 504.3799 506.9472 464.1428 534.5460 459.4585
[2849,] 945.7676 819.9710 747.8369 1230.3295 655.3885 988.9813
[2850,] 694.1423 643.5967 611.1692 806.5671 569.8615 1037.9607
[2851,] 586.1474 565.6662 547.4302 626.4828 528.2804 641.2017
[2852,] 289.7218 289.4203 286.5506 291.7910 287.6667 283.8566
[2853,] 874.2395 834.3811 796.2675 956.0027 762.8760 1030.5434
[2854,] 487.2935 460.7749 441.5393 536.2795 415.8328 771.6455
[2855,] 1000.1196 978.0594 943.0539 1051.4581 931.0306 875.6226
[2856,] 563.7478 575.2728 573.1456 551.0576 592.8071 517.6343
[2857,] 580.6885 576.7642 566.5135 592.0053 566.2215 614.7585
[2858,] 523.8994 524.1715 517.0234 527.7881 521.3611 548.3428
[2859,] 780.6902 802.5558 796.4272 757.9816 835.5745 763.3072
[2860,] 722.7295 708.5198 688.1367 754.7289 679.5745 639.2088
[2861,] 406.2209 408.0487 403.8111 406.4391 408.9525 639.4878
[2862,] 732.5831 718.4385 697.1005 765.4404 688.7108 745.3879
[2863,] 636.2750 652.5151 650.5658 617.9500 680.3347 544.9894
[2864,] 714.1615 773.6108 791.2913 647.3283 895.6308 694.1070
[2865,] 459.9819 445.5503 432.3623 487.4029 419.0111 510.3218
[2866,] 448.3550 484.1447 497.4209 403.0320 552.9303 442.5462
[2867,] 1024.8295 1048.4862 1033.6373 1004.7068 1079.6001 1065.4422
[2868,] 581.1482 596.9802 596.6130 562.8320 622.7765 601.3567
[2869,] 988.2272 862.5533 788.4424 1267.6184 691.3772 881.2599
[2870,] 1210.1162 1175.4153 1126.0647 1287.3972 1103.0594 1260.4876
[2871,] 610.4233 638.2832 643.2646 577.4302 691.2219 508.9334
[2872,] 505.7249 531.3005 537.7687 472.7760 577.1270 526.9615
[2873,] 649.7164 649.0505 638.2902 657.4605 643.1768 457.6026
[2874,] 535.7768 536.9524 530.0404 538.3852 535.6345 523.1593
[2875,] 956.3695 941.6814 911.4133 995.0979 906.2936 1036.4264
[2876,] 695.2624 668.8934 644.6387 751.3981 623.1797 619.6161
[2877,] 573.0430 598.2164 603.0884 541.6305 644.3815 654.0308
[2878,] 840.2373 872.8947 869.9851 803.7101 926.0688 1353.2539
[2879,] 968.1701 923.5968 879.6488 1061.6797 842.7562 794.4455
[2880,] 712.8968 784.2971 808.9954 635.0533 937.8212 908.4483
[2881,] 775.7397 767.7172 747.0704 798.6232 746.5105 843.1771
[2882,] 791.6108 827.0440 827.4118 750.7082 886.9509 674.2462
[2883,] 814.6214 825.9261 812.9010 808.4403 837.6532 777.6809
[2884,] 603.4677 612.0877 607.5468 595.5719 624.1513 473.3603
[2885,] 760.8118 785.0860 780.7498 735.4328 822.6129 824.7440
[2886,] 1399.1229 1404.4593 1368.2673 1413.9879 1396.1915 1443.5876
[2887,] 507.7116 513.8442 509.9454 502.4626 521.6589 633.2541
[2888,] 651.0567 678.8706 681.6489 620.2228 728.7692 603.6270
[2889,] 946.9480 954.7619 935.5136 948.5830 958.0895 815.3376
[2890,] 562.4033 562.2455 554.1884 567.3701 558.3678 629.7319
[2891,] 1010.7442 1017.2765 994.4581 1016.1010 1016.9659 1001.1373
[2892,] 825.2875 835.5962 821.7712 820.6658 845.3668 690.1861
[2893,] 915.7666 1031.2017 1071.9714 784.3692 1279.9019 557.0530
[2894,] 701.0506 668.4059 641.6599 770.6081 614.5840 766.3888
[2895,] 755.1400 748.6750 730.6550 775.1724 731.5573 736.6566
[2896,] 697.3378 635.2966 598.9346 842.1736 548.5341 574.8734
[2897,] 714.3961 715.2386 701.5469 721.4692 710.3316 636.6893
[2898,] 710.0616 787.5714 816.2591 626.9437 958.3326 509.2325
[2899,] 508.4691 504.9267 496.1327 518.2108 495.6069 566.9282
[2900,] 1181.7307 1180.4602 1147.5139 1203.0951 1163.6007 891.9635
[2901,] 497.4485 505.1860 502.2862 489.6696 516.0222 524.2310
[2902,] 879.3965 863.8629 836.0748 917.6755 828.4403 908.6535
[2903,] 468.3249 461.6840 452.0185 482.6821 447.4678 440.8037
[2904,] 648.7828 687.9496 697.1144 604.5382 766.5140 653.0505
[2905,] 554.9465 526.0901 504.5887 609.3405 476.3521 509.1987
[2906,] 738.1258 747.2959 737.1435 732.7684 757.6991 759.8198
[2907,] 1830.1359 1888.7056 1865.0580 1773.4364 1972.0731 1373.5981
[2908,] 1834.9099 1969.8075 1985.4415 1673.3669 2198.2944 1641.3899
[2909,] 827.2594 815.6747 791.9006 857.1757 788.2456 816.7951
[2910,] 859.7248 856.1447 834.5679 877.2429 840.9770 804.9633
[2911,] 550.9901 556.6963 551.8023 546.8294 563.3681 643.6567
[2912,] 833.5191 834.3799 815.6924 843.5715 827.2293 1011.1138
[2913,] 654.4433 681.0395 683.0216 625.1083 728.1385 895.1855
[2914,] 459.8913 485.2613 492.4101 427.3276 531.0826 539.2110
[2915,] 566.8594 576.2116 572.9033 557.3988 589.5919 510.3250
[2916,] 557.5191 588.2418 596.6465 518.3190 647.0259 619.3303
[2917,] 952.5934 1018.4705 1028.3922 875.9969 1139.4288 872.5342
[2918,] 547.3300 594.4146 612.4774 487.6412 698.4036 458.6970
[2919,] 599.8578 605.5016 599.5089 596.4019 611.5597 566.9214
[2920,] 652.9031 618.6657 593.5385 727.3208 563.2401 816.9570
[2921,] 3586.1988 3601.8471 3531.9663 3608.0058 3594.2096 3695.9178
[2922,] 512.6166 506.8102 496.8359 526.0412 493.6028 589.8611
[2923,] 513.8298 522.0007 519.0434 505.5961 533.5248 588.7430
[2924,] 797.7143 751.5106 715.5122 890.9923 678.1165 858.4137
[2925,] 653.8292 646.5967 632.6164 673.2403 629.7137 705.5775
[2926,] 463.1590 472.5844 471.1014 452.6358 486.8236 595.1736
[2927,] 497.5291 477.9761 461.6657 533.9433 442.8635 790.8392
[2928,] 373.0931 369.7518 363.6160 381.1207 361.9620 384.3621
[2929,] 517.5276 529.8551 528.9883 503.2433 549.1436 610.1498
[2930,] 814.2777 848.5518 847.2585 776.0755 904.8061 705.4451
[2931,] 6212.2483 6285.0919 6249.5270 6140.8018 6374.2137 6259.0203
[2932,] 519.2592 550.1835 559.3559 479.3829 607.5866 476.9762
[2933,] 656.4584 655.6258 644.3586 664.7099 649.2087 665.3300
[2934,] 578.8332 606.7450 612.9240 543.9928 659.9619 456.8443
[2935,] 779.0591 692.1604 644.3143 974.9768 581.8259 1114.7859
[2936,] 603.0615 658.7795 681.9096 537.7242 794.0002 842.5031
[2937,] 570.2963 552.9949 536.5058 603.9551 520.6261 619.3411
[2938,] 703.2899 691.7239 673.6343 730.8606 667.1992 775.7759
[2939,] 1486.4715 1609.4334 1631.3062 1338.8341 1834.6029 1607.9089
[2940,] 483.1532 483.3401 476.8114 486.7778 480.6792 460.9725
[2941,] 666.2796 682.3783 678.5846 649.3873 707.1310 639.9905
[2942,] 1069.5389 1109.1089 1100.0671 1028.6910 1169.2227 971.6894
[2943,] 485.8738 486.1516 479.6219 489.3843 483.6293 426.7143
[2944,] 744.7400 746.9278 733.1453 750.3139 744.0420 666.9379
[2945,] 1411.4080 1410.5780 1371.0287 1436.2050 1391.3846 1332.9655
[2946,] 410.9480 393.8196 380.5293 443.3521 364.2806 462.9182
[2947,] 473.0197 477.4939 473.3028 469.9504 482.5514 423.3023
[2948,] 547.5177 539.0709 527.2045 565.6115 521.1886 590.1271
[2949,] 1001.3773 1268.3956 1401.4827 741.5191 1944.1690 1722.1522
[2950,] 512.8782 534.7316 539.0285 485.0774 572.7962 564.0838
[2951,] 803.5713 852.0487 858.8066 746.6001 939.4836 861.5520
[2952,] 323.4238 332.8790 334.2744 311.5120 349.1145 264.9019
[2953,] 600.1614 609.5762 605.5048 591.0473 623.0635 653.9205
[2954,] 676.2806 644.0569 618.9933 743.5186 592.3968 516.1661
[2955,] 640.1087 639.0375 628.2686 647.8561 632.5451 646.6978
[2956,] 513.1936 510.0984 501.4595 522.2703 501.5262 509.9560
[2957,] 795.2098 728.8149 685.5305 934.8896 633.8112 530.3088
[2958,] 407.7965 421.0728 422.6870 391.4774 443.5409 645.8648
[2959,] 516.2642 531.8748 532.7611 497.2544 557.4945 630.1129
[2960,] 498.3675 489.5470 478.3254 516.4999 471.4446 675.5019
[2961,] 677.0191 677.9062 666.1887 682.8520 673.9648 781.2754
[2962,] 556.2886 556.8432 549.2540 560.0802 554.2642 652.2450
[2963,] 422.1406 433.9544 434.5141 407.8559 453.3601 447.8007
[2964,] 402.4940 431.2224 441.6465 366.4488 486.9382 395.5750
[2965,] 901.0114 881.5388 851.5316 945.7981 840.2003 873.8164
[2966,] 598.2247 595.1662 584.8449 608.2524 585.8830 642.4649
[2967,] 575.4903 557.1736 540.1103 611.1056 523.1508 921.3854
[2968,] 1233.5502 1138.9327 1063.3513 1420.0375 982.3958 1283.0427
[2969,] 577.3728 583.4975 578.3061 572.8854 590.8164 493.4671
[2970,] 433.6949 443.2705 442.4099 422.7487 458.1570 523.1932
[2971,] 747.8479 740.0485 721.3429 770.9164 719.9450 846.7856
[2972,] 430.3616 421.0238 410.8000 448.9914 402.8402 915.9470
[2973,] 644.2297 648.5532 640.3926 643.6589 651.5430 718.7128
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[2976,] 639.6438 623.4832 606.0399 674.2245 593.2810 850.8711
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[2979,] 528.6969 561.1045 570.9154 486.9821 622.2724 666.1872
[2980,] 485.2233 479.9481 470.6689 497.5389 467.8548 494.9098
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[2983,] 588.2702 578.1294 564.7753 609.8077 557.2942 602.5117
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[2985,] 542.3758 577.8428 589.2422 496.8187 647.5602 514.2887
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[2987,] 524.2668 560.0673 571.8820 478.1579 629.3385 534.4431
[2988,] 339.8406 345.4531 344.4818 333.6220 353.9496 357.1958
[2989,] 519.6203 508.0261 495.1198 542.6741 485.1512 799.8592
[2990,] 1056.4511 1071.3887 1050.9170 1050.1404 1085.5283 1036.7625
[2991,] 481.7618 459.1344 441.7593 523.6084 419.8991 558.9085
[2992,] 481.7685 484.3503 479.0513 481.6750 485.9403 486.9730
[2993,] 786.6132 779.2737 758.5503 808.5648 758.9265 826.8346
[2994,] 537.7237 579.3373 594.4520 484.3871 665.7136 486.0980
[2995,] 591.8948 597.7390 591.9950 588.0505 604.2287 598.1770
[2996,] 687.4725 700.6135 694.3604 675.3104 719.7160 643.3599
[2997,] 925.4653 969.6697 969.4847 874.6647 1045.6889 923.5036
[2998,] 394.5681 388.5294 380.6928 407.2189 376.1404 430.2668
[2999,] 997.8556 990.4160 961.5455 1025.0032 966.1304 593.1613
[3000,] 413.5322 419.1502 416.6388 408.1436 426.8159 406.4446
[3001,] 375.5487 367.9325 359.6810 390.7814 353.1168 363.7164
[3002,] 851.6011 783.5264 735.7968 991.9646 680.6674 591.1722
[3003,] 513.4627 508.8576 499.4696 524.9570 497.6990 665.0508
[3004,] 1002.9001 1015.5877 996.0195 998.7036 1026.4253 978.4568
[3005,] 668.3710 655.8673 639.2392 695.6515 631.5152 735.6363
[3006,] 1739.6697 1812.0932 1798.2621 1661.4090 1922.5872 1646.3220
[3007,] 831.9593 829.9209 809.9463 846.5514 817.7632 886.4066
[3008,] 330.4801 332.6685 330.1526 329.2479 334.9428 353.8991
[3009,] 1544.1838 1404.3090 1299.7704 1825.9040 1173.4494 1220.9321
[3010,] 1779.8531 1812.0864 1777.1622 1760.2545 1846.7434 1704.0786
[3011,] 391.1470 391.8492 387.3392 392.9627 390.8645 487.4169
[3012,] 445.4717 460.1999 461.8393 427.2719 484.8701 459.4342
[3013,] 503.4405 548.3136 565.8252 445.9681 639.8244 708.3613
[3014,] 546.1648 532.1086 517.5836 573.6156 505.1200 622.0751
[3015,] 509.9065 496.8024 483.2954 535.3923 471.5373 724.5249
[3016,] 744.7381 789.3516 796.4191 694.1892 870.8034 883.9608
[3017,] 478.9505 453.1211 434.3996 526.6476 409.4437 399.6039
[3018,] 511.2427 531.5740 535.0791 485.5192 566.5926 429.2086
[3019,] 568.7214 581.0481 579.2481 554.9048 600.2072 501.4493
[3020,] 625.2786 645.9814 646.6515 601.3567 682.9185 773.7421
[3021,] 689.8779 693.3797 682.6691 691.8296 693.9236 939.4314
[3022,] 508.1418 485.5517 467.6450 550.1267 445.6334 428.5987
[3023,] 503.4480 480.8590 463.0390 545.3545 441.0643 492.9302
[3024,] 3003.8434 2224.0617 1822.0787 4432.0247 1240.3993 2930.2951
[3025,] 613.9118 605.4293 592.1648 634.1155 586.8241 532.6193
[3026,] 2619.0933 2575.2314 2484.9291 2728.8404 2469.8048 2802.4218
[3027,] 376.4270 392.1259 395.7995 356.6681 420.3416 352.3198
[3028,] 787.7938 754.9349 724.3579 854.7848 697.9627 595.1731
[3029,] 782.4776 803.6077 797.0531 760.8541 835.1810 705.6144
[3030,] 216.4147 217.2490 216.2550 215.9638 218.0992 221.4281
[3031,] 398.3025 395.1466 388.5725 406.2614 387.4701 379.6468
[3032,] 707.2194 734.6204 734.6133 676.7476 782.0179 738.2182
[3033,] 542.8351 548.3383 543.4928 538.8908 554.7140 500.0150
[3034,] 4018.1875 4034.3368 3961.7556 4040.9356 4026.2680 3884.2323
[3035,] 540.0373 539.4459 531.5747 545.4436 534.9921 504.0965
[3036,] 467.3548 465.9128 458.8237 473.3824 460.5243 855.6764
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[3038,] 520.8290 535.0235 535.0762 503.8932 557.8464 525.4967
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[3042,] 856.9875 896.8508 897.0306 810.9948 964.2422 775.0341
[3043,] 568.5691 551.6499 535.3719 601.5022 519.9010 706.8541
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[3091,] 1977.6910 2118.4529 2135.2215 1803.1782 2360.8217 2010.5583
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[3125,] 553.4427 525.2080 504.0140 606.6221 476.3942 691.6167
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[3127,] 322.1707 320.0226 315.4478 327.6260 314.7342 355.5629
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[3130,] 477.1869 532.1739 556.2949 408.7429 650.2581 538.7244
[3131,] 521.6869 539.6723 541.7200 499.3922 569.8755 522.2935
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[3139,] 439.3820 422.2473 408.2594 471.6278 392.0527 599.3509
[3140,] 1098.7957 1075.8307 1036.3063 1153.9512 1025.0877 1401.2803
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[3143,] 860.8777 853.5384 830.1363 884.4519 831.9653 889.6129
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[3147,] 606.3249 653.2874 670.8541 550.3763 760.8139 518.4999
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[3151,] 695.0599 708.5995 701.8047 683.3526 727.1352 789.6014
[3152,] 1096.5144 1183.0540 1197.9767 994.8069 1339.7678 1308.4441
[3153,] 419.8791 433.4177 434.9472 403.1996 456.2706 446.8198
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[3161,] 1732.0003 1828.5501 1827.4173 1620.3094 1987.3648 1734.2142
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[3173,] 533.1776 563.7871 572.5035 493.8504 620.8959 444.8112
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[3180,] 562.9400 560.2044 550.8576 571.9703 551.8467 563.5805
[3181,] 484.8462 461.4514 443.6570 528.0928 421.0094 537.8282
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[3185,] 772.1471 747.5837 721.3141 823.2779 702.9718 622.2294
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[3188,] 702.0491 597.3185 547.1241 999.8182 466.3598 529.3359
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[3197,] 1034.7461 1021.8637 989.0558 1071.6386 987.8940 1473.5394
[3198,] 417.2162 422.6492 419.9821 412.1216 429.9540 447.1943
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[3200,] 509.7557 523.5378 523.5783 493.2645 545.7007 526.4894
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[3202,] 354.5598 346.2272 338.1092 370.7280 330.6003 360.9095
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[3207,] 623.7351 547.3921 505.4449 823.9211 437.5008 437.0564
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[3212,] 722.3728 808.9807 843.0053 630.2211 1004.2615 712.0934
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[3217,] 468.7103 472.1802 467.5383 467.1379 475.4528 525.1710
[3218,] 1100.9747 1094.8657 1062.4011 1128.4445 1070.9549 1449.0878
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[3220,] 599.0275 648.1466 667.2303 540.0557 762.8443 778.3592
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[3233,] 616.1609 620.1314 612.5165 615.8027 622.7466 580.9678
[3234,] 709.1108 720.9622 712.8823 699.3271 735.9108 633.0367
[3235,] 2650.5748 2694.3404 2645.5831 2624.9168 2738.1759 2420.2737
[3236,] 565.6169 554.3261 540.7716 588.7160 531.6177 636.7285
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[3238,] 1252.9135 4041.3173 5930.9557 373.9062 10276.0904 1393.1620
[3239,] 373.9682 383.0439 383.1724 363.2027 397.7981 413.9590
[3240,] 690.5322 670.6519 649.0212 733.5579 633.9497 762.2262
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[3249,] 1143.5611 1151.3048 1123.9508 1150.1012 1150.7899 988.6807
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[3259,] 805.5045 826.9100 819.3442 784.5409 858.0062 1323.8894
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[3261,] 479.3907 486.2470 483.1702 472.8034 495.6070 498.6821
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[3263,] 1218.3964 1220.7622 1188.3482 1234.7897 1209.6618 1190.2826
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[1100,] 3773.7424 3956.0119 3988.7624 3998.3485
[1101,] 4249.8312 4524.2540 4516.4300 4336.9607
[1102,] 3432.9020 3669.8734 3680.9363 3587.4637
[1103,] 4344.5598 4721.3609 4670.5685 4293.6297
[1104,] 2841.4030 2999.8479 3035.5866 3069.5680
[1105,] 3472.5487 3831.4927 3791.7687 3457.4431
[1106,] 4462.1476 4731.6242 4727.9579 4563.3464
[1107,] 3687.1562 3764.7047 3844.1527 4067.2880
[1108,] 3661.6223 3966.1066 3948.8738 3720.0396
[1109,] 2333.7233 2540.1721 2545.0850 2446.3987
[1110,] 3485.2772 3761.0067 3755.6801 3584.0070
[1111,] 4683.1987 5062.1244 5019.0500 4665.4048
[1112,] 3455.2593 3738.2992 3730.0322 3546.4840
[1113,] 2771.8183 2952.2974 2977.5050 2963.7731
[1114,] 3643.9563 3922.8749 3916.5183 3739.3753
[1115,] 1810.7044 1928.2145 1954.7152 1976.9415
[1116,] 3385.9893 3566.4255 3601.0173 3622.8889
[1117,] 2460.8207 2767.6070 2733.5270 2448.6762
[1118,] 4461.9025 4781.5819 4756.8146 4496.3097
[1119,] 2231.8442 2512.6091 2484.0501 2232.2062
[1120,] 4190.2860 4344.0218 4387.5033 4445.6113
[1121,] 3440.1418 3686.6274 3693.7033 3581.2508
[1122,] 3864.7974 4054.8498 4085.5362 4080.7110
[1123,] 2438.9150 2563.5769 2604.3846 2673.2907
[1124,] 4156.5927 4425.4718 4419.7434 4247.7775
[1125,] 3085.2261 3345.9993 3344.3808 3193.4304
[1126,] 2736.4683 3130.7947 3064.8067 2635.9009
[1127,] 3454.1223 4311.7272 4068.2491 2757.5999
[1128,] 4577.2433 4928.3764 4893.6230 4584.5378
[1129,] 2964.6213 3054.8405 3121.1072 3299.8071
[1130,] 3195.3047 3546.8975 3509.6244 3186.2816
[1131,] 3593.2663 3876.1576 3868.4984 3682.1131
[1132,] 3652.9508 4160.8220 4059.7616 3423.2005
[1133,] 2967.3348 3120.2387 3161.2164 3213.5941
[1134,] 6034.5913 6254.6801 6268.7793 6200.9505
[1135,] 4537.5162 4760.1146 4778.1176 4712.3427
[1136,] 3727.0895 4090.3662 4047.7110 3703.2471
[1137,] 2628.2817 3214.6099 3062.6675 2288.8123
[1138,] 4428.6104 4686.6692 4686.8319 4541.1483
[1139,] 2778.9875 2994.3668 3005.2847 2921.4094
[1140,] 4126.7020 4217.7607 4284.8254 4464.1559
[1141,] 4161.1481 4357.1941 4382.2977 4355.2080
[1142,] 3482.7171 3709.1973 3724.4205 3648.1130
[1143,] 1413.5463 1673.2579 1620.3473 1326.0100
[1144,] 3775.8861 4390.3001 4241.8532 3381.1759
[1145,] 2994.5953 3311.7722 3285.1178 3016.7838
[1146,] 2830.4025 3079.8637 3077.6901 2930.8659
[1147,] 3207.5968 3434.1593 3448.4033 3366.8952
[1148,] 2613.1598 2841.3553 2843.0544 2720.9881
[1149,] 2980.8953 3273.7905 3257.2008 3034.7044
[1150,] 2808.2405 3021.9002 3034.1684 2956.5424
[1151,] 2861.9695 3071.9857 3086.9191 3018.7335
[1152,] 3415.4741 3804.3043 3751.3430 3360.2327
[1153,] 3856.7457 4322.7046 4236.2026 3671.4566
[1154,] 2975.3448 3396.7520 3325.1335 2858.2011
[1155,] 3047.6908 3301.8319 3302.4671 3161.8271
[1156,] 3978.8422 4340.2271 4296.7012 3946.5216
[1157,] 3053.3323 3375.4154 3347.5294 3074.1558
[1158,] 4440.2520 4700.5923 4700.1296 4551.1270
[1159,] 4907.8177 5122.8910 5153.0388 5133.6923
[1160,] 2430.7359 2756.1424 2713.6043 2389.5560
[1161,] 2933.0399 3208.6331 3197.6957 3006.5821
[1162,] 2842.3747 3161.9390 3130.4501 2849.8344
[1163,] 2875.6666 3285.7684 3218.2946 2769.0329
[1164,] 2957.5746 3108.1904 3149.6733 3205.2280
[1165,] 3146.5257 3330.8686 3361.7719 3363.6441
[1166,] 1774.7248 1948.0687 1949.6780 1855.5958
[1167,] 4868.8954 5169.2599 5163.1151 4974.0857
[1168,] 881.0450 921.0893 934.7640 958.9013
[1169,] 2971.8690 3029.3554 3109.0471 3356.0549
[1170,] 2607.8955 2899.9166 2874.6614 2629.6554
[1171,] 4203.2984 4635.8691 4560.7929 4070.0062
[1172,] 3732.5553 4086.1558 4047.5687 3722.1501
[1173,] 3058.4562 3317.5055 3316.2388 3166.6196
[1174,] 2064.1095 2210.9610 2233.0056 2225.7576
[1175,] 2140.2675 2269.0815 2300.7735 2336.0863
[1176,] 3945.5129 4438.1108 4340.2618 3725.5552
[1177,] 1767.8926 1992.2051 1972.5042 1781.9211
[1178,] 2840.0040 3333.8337 3230.8284 2626.1669
[1179,] 2355.6255 2613.2800 2597.1561 2400.7044
[1180,] 3826.5054 4106.1326 4098.1891 3913.8105
[1181,] 983.3073 1071.9106 1071.6143 1020.0215
[1182,] 2895.4918 3208.2597 3180.8178 2917.8115
[1183,] 2842.4600 2984.0555 3026.6991 3095.2781
[1184,] 4523.3713 4860.3020 4830.0083 4542.6381
[1185,] 3126.0208 3412.6985 3400.7672 3201.5794
[1186,] 3337.2531 3674.8540 3643.9563 3349.3899
[1187,] 4251.5075 4436.2643 4465.7656 4466.0140
[1188,] 3305.9688 3519.3841 3541.0234 3497.4708
[1189,] 2183.4801 2470.5435 2438.4549 2170.4342
[1190,] 2635.6536 2546.6218 2680.6710 3217.8685
[1191,] 2631.5952 2900.1719 2885.2203 2687.2897
[1192,] 4367.9384 4729.8573 4685.4597 4337.7398
[1193,] 2025.1716 2211.1571 2215.8360 2125.6371
[1194,] 2863.4486 3138.7275 3126.4336 2932.2726
[1195,] 3380.4263 3651.0901 3648.2745 3489.4936
[1196,] 1926.7922 2033.8897 2067.6602 2123.6852
[1197,] 3913.2238 4660.5274 4455.3862 3326.5803
[1198,] 2514.4620 2756.7040 2750.8859 2594.5228
[1199,] 2119.6648 2317.3285 2320.0059 2217.4246
[1200,] 2706.3695 2995.2197 2973.7144 2738.6304
[1201,] 2486.7890 2703.4643 2707.8620 2600.0331
[1202,] 991.0543 1263.8171 1182.6770 845.1722
[1203,] 3727.9188 3871.3103 3920.4026 4013.2120
[1204,] 4367.5637 4562.9649 4588.2689 4563.6383
[1205,] 1514.3223 1633.0705 1645.5308 1618.4779
[1206,] 3346.7055 3554.6755 3578.0313 3547.1666
[1207,] 2331.9945 2651.0411 2608.2636 2294.7136
[1208,] 2062.2359 2221.2060 2238.2063 2206.6448
[1209,] 3931.6853 4253.2792 4227.3644 3956.9993
[1210,] 646.7566 775.0308 734.3155 580.0589
[1211,] 3508.3721 3801.4161 3788.7183 3582.6560
[1212,] 847.3199 904.2270 909.0982 892.1028
[1213,] 4376.4601 4600.4163 4613.8842 4532.4840
[1214,] 2934.3939 3349.2768 3280.2638 2822.3674
[1215,] 4049.7816 4326.2473 4317.4212 4136.1407
[1216,] 1837.4024 1914.7542 1958.8856 2065.5429
[1217,] 3796.0028 4092.0652 4077.2370 3863.1545
[1218,] 1702.5603 1794.6542 1826.7650 1885.8187
[1219,] 2420.9206 2721.3324 2689.5770 2413.6488
[1220,] 2291.2516 2519.8782 2514.6419 2368.4074
[1221,] 2249.7116 2444.7827 2452.6849 2369.1802
[1222,] 3025.0446 3402.4920 3350.5809 2971.2746
[1223,] 1531.7215 1763.4808 1729.1217 1497.1172
[1224,] 707.2956 673.2356 704.8524 875.6462
[1225,] 3533.3605 3949.3147 3885.5459 3427.3465
[1226,] 2585.3411 2840.9791 2830.7243 2654.2080
[1227,] 3552.4686 3776.2807 3793.3974 3722.5081
[1228,] 3855.8729 4039.7513 4072.6659 4079.1420
[1229,] 4304.0101 4586.2144 4575.2327 4382.2114
[1230,] 2047.6982 2487.5596 2385.0789 1838.3497
[1231,] 3160.6271 3511.6690 3472.9565 3152.2296
[1232,] 3433.9318 3667.3542 3679.8885 3593.2780
[1233,] 2736.1610 3096.8261 3045.3622 2679.3731
[1234,] 1831.0127 1998.7637 2004.8541 1930.1961
[1235,] 2893.7683 3441.6890 3314.5512 2617.0502
[1236,] 4323.2836 4671.4225 4632.6567 4310.5212
[1237,] 1939.2855 2151.6394 2142.2277 1992.5050
[1238,] 2707.1162 3404.1086 3208.6896 2244.2921
[1239,] 2132.8024 2372.0347 2357.6586 2177.1768
[1240,] 2250.8380 2526.7588 2500.6781 2259.6517
[1241,] 1614.6242 1743.9389 1757.2802 1727.0498
[1242,] 3554.9110 3986.9240 3916.1114 3428.2407
[1243,] 4995.5454 5250.7796 5266.0271 5171.9661
[1244,] 4023.4734 4252.0871 4263.6889 4178.0054
[1245,] 2744.3172 3106.0757 3054.3302 2687.4905
[1246,] 2751.6885 3055.0073 3028.3972 2770.1068
[1247,] 2873.8872 3406.9952 3286.5492 2613.7947
[1248,] 4125.3711 4485.5520 4441.1965 4085.7895
[1249,] 2441.0166 2662.3987 2663.4473 2540.3011
[1250,] 3567.2801 3875.9365 3857.6189 3618.3904
[1251,] 3547.5081 3867.0153 3844.2476 3582.8278
[1252,] 2279.7793 2638.0335 2577.1717 2189.0299
[1253,] 3765.6023 4080.4619 4057.9904 3810.1354
[1254,] 1851.9976 2108.0633 2077.4902 1837.0781
[1255,] 3096.7056 3289.1888 3316.0812 3301.2000
[1256,] 3813.8238 3912.2314 3978.9089 4152.8106
[1257,] 1388.1462 1494.3694 1505.8479 1483.2476
[1258,] 3066.4925 3303.0262 3311.2652 3207.7134
[1259,] 2319.6063 2591.7672 2568.7532 2341.2013
[1260,] 3187.8593 3253.1960 3332.9148 3579.0470
[1261,] 2151.2657 2256.5395 2298.1168 2383.1369
[1262,] 1678.2600 1785.7540 1810.6309 1834.7112
[1263,] 2879.7787 3144.5405 3137.0186 2964.2863
[1264,] 1598.0957 1822.0315 1794.8974 1584.3590
[1265,] 3299.5241 3533.5169 3546.2013 3460.4582
[1266,] 3386.5878 3593.9147 3617.4230 3585.3319
[1267,] 2995.4032 3387.6014 3328.9070 2918.8940
[1268,] 1570.0485 1918.2406 1835.2859 1416.0438
[1269,] 2971.9284 3238.7288 3232.9803 3061.0410
[1270,] 3607.8401 3930.1924 3905.8191 3640.0111
[1271,] 1889.9823 2064.1296 2069.2847 1988.6110
[1272,] 3747.9202 4101.4680 4062.7705 3737.6980
[1273,] 2370.8345 2567.9468 2577.4923 2498.0304
[1274,] 4953.4328 5232.7113 5237.0943 5093.8387
[1275,] 2996.4776 3348.0022 3306.7637 2973.5719
[1276,] 2787.1940 3065.4363 3050.2262 2843.0792
[1277,] 3492.0626 3844.8380 3808.5125 3483.8517
[1278,] 2043.0896 2222.7438 2230.6027 2155.2661
[1279,] 473.3553 490.3969 492.3960 489.4942
[1280,] 3135.3154 3492.9944 3451.1091 3116.1219
[1281,] 3186.4499 3514.4886 3485.8943 3210.7968
[1282,] 3014.9747 3340.9545 3310.8638 3027.2256
[1283,] 4135.7598 4526.2474 4469.0072 4052.7568
[1284,] 1486.2449 1688.2638 1664.2332 1477.3713
[1285,] 2026.1495 2328.3355 2283.7433 1976.1986
[1286,] 2734.3764 3079.6883 3034.7749 2696.9721
[1287,] 4294.2009 4560.3724 4556.0940 4394.9248
[1288,] 2695.9981 2939.5951 2936.4621 2787.4482
[1289,] 4282.4620 4564.6501 4553.6349 4359.8393
[1290,] 1629.5096 1664.7614 1716.8604 1884.8276
[1291,] 2512.9128 2872.9367 2816.9270 2438.6938
[1292,] 3921.7859 4277.8512 4237.4852 3898.1455
[1293,] 3605.5505 3953.1154 3918.0811 3602.2760
[1294,] 2159.0462 2415.2089 2394.4638 2185.0737
[1295,] 3449.7149 3630.2115 3664.5623 3682.0500
[1296,] 2501.7783 2662.2161 2691.0580 2696.8877
[1297,] 2220.5841 2541.4295 2495.4368 2167.9725
[1298,] 2340.3533 2529.3082 2541.6251 2477.0874
[1299,] 3232.7011 3467.4834 3478.6383 3381.2345
[1300,] 3602.1633 3980.3156 3932.2866 3556.8339
[1301,] 2984.6675 3282.3952 3263.8220 3032.2245
[1302,] 2242.5644 2467.8148 2462.9634 2318.4992
[1303,] 2356.0582 2763.5942 2686.0378 2209.2714
[1304,] 3573.4460 4030.2023 3948.5870 3413.7627
[1305,] 2806.4120 3004.3571 3023.0957 2976.2557
[1306,] 2491.1847 2754.2467 2739.2659 2540.1050
[1307,] 1984.3599 2189.2425 2184.4386 2052.1153
[1308,] 2956.3362 3379.9332 3307.0685 2833.8582
[1309,] 3230.7985 3549.4642 3526.7896 3265.9675
[1310,] 3041.3241 3565.8850 3452.4965 2801.2065
[1311,] 2955.6677 3266.1832 3241.7734 2983.2875
[1312,] 1864.4519 2074.5780 2063.9100 1910.4838
[1313,] 2442.7913 2746.3088 2713.2960 2433.0832
[1314,] 3355.0195 3570.8428 3590.9287 3543.9727
[1315,] 3141.2096 3418.9295 3410.9645 3230.6315
[1316,] 2542.2021 2716.9667 2739.6692 2720.7734
[1317,] 3171.0167 3589.6409 3525.9188 3068.7992
[1318,] 3652.7927 4009.2016 3970.0650 3637.7892
[1319,] 1515.9703 1643.5353 1652.4376 1608.3402
[1320,] 1637.0678 1891.7418 1853.0255 1593.3005
[1321,] 5357.0806 5608.6846 5627.2999 5546.7897
[1322,] 1026.4513 1170.6914 1149.3950 1005.6099
[1323,] 2346.7779 2552.3277 2557.8804 2461.3411
[1324,] 2557.4167 2986.1781 2902.0718 2401.3301
[1325,] 2060.5360 2254.2312 2256.7754 2155.7287
[1326,] 2185.5552 2202.3221 2280.1599 2554.4213
[1327,] 2367.2222 2603.7986 2596.7896 2441.8576
[1328,] 2388.9009 2657.3939 2637.3633 2423.2545
[1329,] 2575.8559 2880.8842 2849.5654 2577.2929
[1330,] 2872.2292 3058.3883 3083.3987 3062.8500
[1331,] 2410.1150 2722.4631 2685.6799 2386.3126
[1332,] 3124.1510 3472.5479 3434.4670 3116.1740
[1333,] 2167.9570 2491.2442 2443.5439 2106.9293
[1334,] 5106.9849 5459.9587 5435.4744 5153.7324
[1335,] 4411.5058 4677.8135 4674.0042 4510.7053
[1336,] 3351.7013 3413.2457 3500.0108 3753.5191
[1337,] 2360.0741 2539.6990 2556.2741 2510.7015
[1338,] 2555.7915 2785.6947 2785.7417 2657.6152
[1339,] 2812.2961 3181.4729 3128.0916 2753.5148
[1340,] 3146.3371 3330.6982 3361.5915 3363.4256
[1341,] 2196.8625 2644.7997 2542.5013 1989.7973
[1342,] 4207.2135 4420.6219 4438.1568 4381.4650
[1343,] 3064.8468 3226.8202 3266.0233 3311.7440
[1344,] 3395.4323 3471.4990 3551.6602 3779.8170
[1345,] 2985.2987 3243.0082 3241.2625 3088.4807
[1346,] 4148.5223 4713.3307 4580.7657 3825.6497
[1347,] 510.9932 577.8516 559.3869 469.1490
[1348,] 2851.3265 3224.5441 3170.3043 2791.6608
[1349,] 3397.4742 3827.1804 3757.1269 3287.3449
[1350,] 3033.0372 3298.0934 3293.9559 3130.3347
[1351,] 2329.1822 2639.2531 2600.2685 2302.8855
[1352,] 4058.2434 4262.7960 4283.8131 4241.4463
[1353,] 2446.2552 2831.1249 2763.1041 2329.9374
[1354,] 2699.2354 3210.2668 3092.1404 2451.8811
[1355,] 2713.7228 3000.7815 2980.2014 2749.2174
[1356,] 2485.4739 2829.0165 2779.6212 2428.8332
[1357,] 2346.9894 2591.9119 2580.9812 2408.3431
[1358,] 1888.2628 2129.6205 2106.4232 1896.9331
[1359,] 4951.1083 5345.0712 5301.8279 4937.5209
[1360,] 2017.2829 2214.6562 2214.3411 2100.7165
[1361,] 3287.2529 3570.7666 3562.7996 3374.3359
[1362,] 2623.9355 2777.1387 2810.0185 2836.0701
[1363,] 3133.3901 3531.3624 3472.4426 3061.8465
[1364,] 2972.6512 3370.5925 3309.0763 2885.4605
[1365,] 2516.6554 2959.7076 2867.7474 2339.0661
[1366,] 1856.8315 2216.1838 2141.3007 1720.3787
[1367,] 3648.5972 3641.9309 3756.0928 4144.1565
[1368,] 2767.2896 3064.3719 3040.7566 2795.7080
[1369,] 2485.8843 2531.7690 2606.4165 2841.7139
[1370,] 2514.5027 2728.7174 2734.6153 2634.3115
[1371,] 3315.5959 3546.1851 3560.2482 3482.2983
[1372,] 2835.7458 3031.0610 3051.5174 3011.1767
[1373,] 1095.7106 1317.7837 1266.6975 1004.2705
[1374,] 2916.0001 3308.7481 3249.4261 2832.3712
[1375,] 2029.2169 2217.4951 2221.3426 2127.1062
[1376,] 3511.5654 3814.9283 3797.8730 3572.1986
[1377,] 3198.7105 3568.7391 3524.9911 3162.8709
[1378,] 2753.7385 3181.6984 3101.4938 2613.8003
[1379,] 2735.0649 3171.8395 3087.3397 2581.0529
[1380,] 1679.6187 1841.7233 1844.1289 1759.9496
[1381,] 2894.7100 3036.5984 3080.2237 3150.5190
[1382,] 2663.8153 2801.1610 2841.1404 2900.2701
[1383,] 1808.7138 1852.1466 1908.3227 2082.8489
[1384,] 5239.7728 5559.2953 5548.8273 5337.3166
[1385,] 1233.9115 1286.7231 1313.8590 1378.1821
[1386,] 2589.0973 2811.0635 2814.9726 2704.4826
[1387,] 1745.9319 1931.8797 1927.0307 1805.8453
[1388,] 410.2498 417.7707 422.0923 432.8815
[1389,] 2656.1240 2855.8530 2870.0732 2803.7539
[1390,] 4733.5114 5237.1222 5141.7711 4563.1630
[1391,] 2723.6044 2878.5397 2913.3806 2942.8092
[1392,] 3884.9774 4105.3310 4123.0754 4061.5840
[1393,] 2080.8897 2248.3021 2262.3776 2215.5893
[1394,] 2275.8418 2709.3670 2616.3021 2093.1974
[1395,] 2767.7768 3057.9360 3037.2619 2805.4325
[1396,] 2140.9827 2327.5804 2335.5039 2255.7643
[1397,] 3067.0275 3255.2742 3283.5089 3276.8103
[1398,] 1951.3407 2069.7043 2099.5857 2134.0847
[1399,] 2198.7243 2429.6294 2420.8197 2261.2314
[1400,] 2685.9352 2921.4770 2921.2522 2786.0926
[1401,] 2071.1962 2249.8610 2258.9829 2189.1820
[1402,] 2953.5645 3369.6328 3299.9869 2840.3275
[1403,] 1682.3908 2006.7294 1940.3660 1566.6490
[1404,] 4638.3565 5033.8753 4982.5436 4595.1255
[1405,] 1719.9671 1906.8216 1900.5214 1774.6357
[1406,] 2395.6673 2712.9887 2673.3858 2364.9018
[1407,] 3156.7224 3318.7528 3358.9416 3406.1215
[1408,] 3168.6249 3563.6096 3508.4363 3099.2466
[1409,] 2449.1117 2641.7147 2655.1267 2588.8511
[1410,] 3307.3662 3517.5209 3540.6108 3503.6830
[1411,] 2886.7045 3086.2849 3106.0623 3059.4665
[1412,] 2570.8700 2752.6042 2772.9055 2740.6910
[1413,] 2151.2285 2365.2404 2362.0314 2230.6170
[1414,] 1811.1059 1984.0549 1987.3924 1899.9011
[1415,] 1894.7569 2094.0426 2088.8287 1959.8706
[1416,] 5518.4159 5883.3393 5851.2869 5537.2580
[1417,] 1883.6643 2099.2711 2086.8588 1925.2171
[1418,] 2661.7311 2963.0254 2935.0293 2675.6687
[1419,] 3439.3153 3566.9211 3622.9341 3749.8026
[1420,] 4880.4812 5252.5687 5216.4690 4890.3955
[1421,] 3683.2757 3690.8010 3800.6790 4157.9353
[1422,] 2536.3719 2569.5794 2651.6200 2918.5486
[1423,] 6122.6648 6318.1963 6339.2848 6310.0041
[1424,] 1711.2060 1833.7672 1853.8095 1851.4738
[1425,] 4327.2878 4539.6190 4557.8438 4500.9224
[1426,] 2106.9072 2192.0489 2240.5298 2364.3957
[1427,] 2485.1387 2691.1330 2699.9479 2613.6109
[1428,] 1571.4733 1723.9362 1725.4012 1642.7694
[1429,] 2070.5115 2295.0230 2284.9536 2125.2129
[1430,] 3051.9698 3559.8773 3453.6386 2833.5564
[1431,] 2661.1857 2921.2748 2910.3696 2728.5852
[1432,] 4727.2066 4999.6680 5002.3080 4856.8285
[1433,] 3014.0610 3191.1095 3224.2642 3234.5860
[1434,] 2319.9867 2570.8710 2556.8696 2370.0631
[1435,] 2690.0034 2809.3073 2857.1415 2954.5711
[1436,] 2349.3581 2558.2465 2562.4605 2459.5782
[1437,] 1389.3203 1470.5561 1492.3274 1520.3429
[1438,] 1879.5077 2124.8915 2099.7161 1881.8213
[1439,] 1486.8548 1667.6100 1652.6796 1503.8525
[1440,] 2384.9884 2770.6294 2702.4273 2265.3536
[1441,] 2885.7624 3160.6273 3148.9883 2957.4953
[1442,] 3066.8683 3443.0616 3392.2976 3018.1359
[1443,] 3688.2788 3959.0456 3955.7615 3796.3045
[1444,] 3374.3565 3533.6844 3576.9648 3642.5855
[1445,] 4320.1414 4750.6531 4676.9463 4197.6987
[1446,] 3247.5060 3424.4445 3460.1174 3479.6334
[1447,] 3262.3611 3683.7626 3617.1779 3155.4896
[1448,] 4738.7769 5122.4652 5078.5221 4720.1075
[1449,] 4374.1717 4396.8369 4492.7514 4826.3833
[1450,] 2818.7214 3156.7665 3116.8757 2799.7439
[1451,] 1259.7573 1376.2076 1377.9524 1317.6093
[1452,] 910.4723 1090.6981 1045.6920 831.3601
[1453,] 1547.3843 1705.7873 1703.4927 1605.5619
[1454,] 2487.0900 2807.5205 2768.0798 2459.9938
[1455,] 2105.0800 2257.6575 2278.5745 2263.0566
[1456,] 4762.7569 4994.9932 5015.1561 4952.4074
[1457,] 3207.4375 3494.9945 3483.7604 3285.2610
[1458,] 2407.9798 2805.4791 2731.9147 2273.7768
[1459,] 1965.3845 2253.2583 2213.1484 1923.2536
[1460,] 2440.0850 2674.4042 2669.9938 2522.1569
[1461,] 1746.2945 2042.7919 1991.7954 1668.2425
[1462,] 2595.7034 2965.4526 2907.0903 2516.0996
[1463,] 1896.8975 2260.1950 2186.0168 1759.3499
[1464,] 3684.5240 3839.3935 3884.1317 3957.0941
[1465,] 2262.1199 2434.2626 2451.9227 2416.7009
[1466,] 1330.0580 1426.2383 1439.3564 1427.8541
[1467,] 1631.1324 1880.6522 1843.9107 1592.4166
[1468,] 3455.9661 3789.0570 3759.6839 3477.8448
[1469,] 2524.3286 3112.6113 2960.0880 2176.7015
[1470,] 3412.8665 3576.9153 3618.1458 3671.5484
[1471,] 1731.7640 1916.8607 1911.7855 1790.5899
[1472,] 2221.8326 2408.1531 2419.1320 2348.2113
[1473,] 3326.1400 3654.6902 3627.6551 3350.5082
[1474,] 3467.3918 3630.6507 3672.0080 3723.2617
[1475,] 3068.0450 3276.2378 3296.2562 3249.8412
[1476,] 1346.4282 1411.0087 1437.8269 1493.3170
[1477,] 716.5530 750.2897 757.0874 759.3618
[1478,] 2812.2297 3183.2860 3129.0945 2751.1182
[1479,] 3590.1395 3975.3407 3924.3843 3535.1424
[1480,] 1815.9849 2166.4224 2093.6208 1684.7690
[1481,] 2624.9494 2739.0286 2787.8559 2894.7989
[1482,] 3244.2888 3479.0137 3490.6846 3395.0169
[1483,] 466.5721 443.7898 461.6358 545.3105
[1484,] 1502.7709 1819.7895 1746.9219 1370.4851
[1485,] 1654.9635 2125.8515 1994.3366 1390.8673
[1486,] 1774.7070 1828.2904 1878.7349 2027.3105
[1487,] 4792.0882 5055.4273 5063.1947 4940.9244
[1488,] 1681.3301 2060.6484 1971.2698 1506.8532
[1489,] 2019.5050 2219.7647 2218.3105 2099.3133
[1490,] 2107.8161 2375.5412 2348.3072 2111.6764
[1491,] 2163.9142 2335.3989 2350.2674 2301.7005
[1492,] 2854.4216 3049.1439 3070.2440 3031.8911
[1493,] 2094.3880 2377.3835 2343.2056 2077.1885
[1494,] 2059.8390 2241.1015 2248.8008 2172.3624
[1495,] 2042.6294 2427.2777 2347.1914 1896.9989
[1496,] 2224.1688 2299.2440 2355.6682 2508.7482
[1497,] 2261.1224 2729.2147 2621.1988 2036.6332
[1498,] 2461.3452 2764.6430 2732.0612 2453.7686
[1499,] 1965.5895 2088.7041 2117.0487 2142.8093
[1500,] 2417.6833 2592.4169 2612.1483 2578.0439
[1501,] 2418.4636 2458.9292 2532.9662 2775.5543
[1502,] 2273.2718 2348.2335 2407.1168 2565.5009
[1503,] 3338.6932 3478.7926 3532.7542 3630.7884
[1504,] 2209.6528 2388.7419 2402.1062 2343.2847
[1505,] 665.9057 676.7229 689.0414 729.2971
[1506,] 2157.3371 2464.5267 2423.1115 2116.4327
[1507,] 1371.1380 1489.4238 1495.1480 1446.4794
[1508,] 2132.5185 2435.2576 2393.8741 2096.0619
[1509,] 1818.0749 2000.4334 2000.0499 1894.8519
[1510,] 2243.0036 2442.8941 2448.6493 2354.7107
[1511,] 2300.7878 2522.7947 2520.5317 2388.3183
[1512,] 3257.1818 3417.4211 3460.3413 3515.2720
[1513,] 3111.7553 3435.2896 3407.6035 3135.7336
[1514,] 4063.3644 4421.7580 4378.9973 4031.0168
[1515,] 1460.0052 1520.6690 1554.0106 1636.6216
[1516,] 2955.8961 3161.4144 3180.2590 3125.1128
[1517,] 3363.2296 3084.0362 3307.8424 4246.0810
[1518,] 2955.4577 3388.1147 3311.3036 2821.3835
[1519,] 1827.1386 1965.5024 1983.9637 1967.4141
[1520,] 1970.2998 2387.3546 2290.5528 1777.9434
[1521,] 1518.1662 1629.6318 1645.2896 1633.3940
[1522,] 2382.9983 2629.3184 2618.5310 2445.8130
[1523,] 3522.6738 3818.2112 3804.3974 3592.6437
[1524,] 1837.1268 1907.8804 1954.6412 2074.9649
[1525,] 1548.0844 1698.8953 1699.8135 1616.3771
[1526,] 3006.4281 3222.8278 3238.9533 3170.3959
[1527,] 1745.0747 1927.4173 1924.0457 1809.5260
[1528,] 2325.3642 2527.0312 2533.7643 2444.0273
[1529,] 1166.4112 1351.9498 1320.7089 1122.7277
[1530,] 2436.7004 2391.7887 2501.1822 2926.8273
[1531,] 1911.8657 2066.9291 2080.6297 2038.5999
[1532,] 2501.1821 2662.5905 2691.0092 2694.9182
[1533,] 1018.1962 1170.0453 1144.9383 987.1037
[1534,] 2488.0264 2825.3554 2778.6803 2439.6479
[1535,] 1760.3047 1946.8574 1942.3463 1821.6535
[1536,] 2990.1388 3140.3932 3183.4562 3244.0056
[1537,] 2614.5850 3049.5491 2965.0609 2453.7499
[1538,] 3059.9130 3110.5602 3196.8148 3465.2114
[1539,] 2506.3469 2675.7612 2700.4656 2690.1475
[1540,] 2153.3835 2344.5549 2350.9466 2263.2651
[1541,] 1579.8230 1824.5471 1787.6694 1538.3731
[1542,] 3520.4094 3710.9823 3740.8884 3733.1172
[1543,] 1168.3658 1250.8135 1263.0068 1256.4192
[1544,] 1252.6072 1337.1062 1351.8009 1353.4655
[1545,] 3135.5561 3451.4233 3427.3075 3171.9365
[1546,] 2122.5434 2306.3285 2314.8692 2239.2308
[1547,] 1328.8205 1428.7254 1440.2392 1421.1220
[1548,] 2303.9325 2441.9775 2474.4993 2510.5122
[1549,] 1294.0311 1408.6833 1412.4500 1359.1228
[1550,] 2180.5159 2294.2971 2333.2833 2402.7897
[1551,] 2739.9053 2902.5879 2934.9994 2951.2927
[1552,] 3646.9379 4050.4561 3991.2543 3567.9197
[1553,] 4095.4331 4330.7891 4338.3729 4231.0120
[1554,] 1728.2182 1852.1072 1872.2914 1869.4077
[1555,] 2764.2980 3011.3362 3008.7296 2860.1824
[1556,] 2228.7672 2493.5674 2471.7310 2249.6085
[1557,] 2493.0764 3073.2892 2922.9441 2151.5397
[1558,] 2540.9769 2861.7688 2823.1243 2518.6035
[1559,] 1775.0038 1980.3473 1968.6301 1814.3889
[1560,] 1378.9872 1518.3246 1515.6191 1427.6633
[1561,] 1883.1132 1849.7138 1939.5937 2292.8011
[1562,] 716.6803 697.4603 724.9056 852.6329
[1563,] 2536.6896 2784.9461 2776.9815 2610.7229
[1564,] 1669.0672 1975.6856 1915.6887 1571.9889
[1565,] 1803.6511 1957.2536 1968.5551 1917.3851
[1566,] 3997.6273 4398.4440 4337.7888 3910.2961
[1567,] 2856.1752 3078.3535 3088.1148 2995.9462
[1568,] 2481.1439 2697.7575 2702.0832 2593.8581
[1569,] 1171.8094 1330.0377 1310.7911 1161.3263
[1570,] 3098.7283 3251.2924 3294.5863 3360.6858
[1571,] 2783.2188 3126.2360 3083.4205 2754.0369
[1572,] 1903.8467 2103.0296 2098.1244 1970.4530
[1573,] 1993.6185 1965.8890 2055.5372 2409.9632
[1574,] 2862.6795 3096.5799 3101.6009 2987.0192
[1575,] 2489.6673 2719.2172 2718.2890 2584.8975
[1576,] 3100.2832 3352.7731 3354.8217 3221.6880
[1577,] 1695.8461 1779.5402 1814.7781 1890.6116
[1578,] 1388.6336 1901.3064 1731.7687 1071.4220
[1579,] 3075.7987 3435.3029 3391.8088 3049.2677
[1580,] 2209.8883 2515.5804 2475.8676 2175.2210
[1581,] 2411.0665 2557.5613 2588.7645 2611.1692
[1582,] 947.7379 996.5367 1010.6149 1030.3903
[1583,] 1560.1099 1685.5663 1697.6437 1665.3994
[1584,] 2738.9622 3016.3535 3000.4269 2790.3328
[1585,] 1818.1990 2082.2993 2047.2409 1788.7767
[1586,] 1682.1642 1869.1852 1861.2535 1729.6983
[1587,] 1527.3006 1562.6996 1609.5035 1760.1361
[1588,] 912.4513 987.8785 988.7428 948.0154
[1589,] 1591.7669 1782.5931 1769.0856 1618.0742
[1590,] 569.0909 530.2361 556.7506 703.1145
[1591,] 2362.9745 2525.5870 2549.2330 2537.5678
[1592,] 2795.5169 2925.0953 2972.4672 3060.8430
[1593,] 2405.1918 2624.4836 2625.4737 2504.3269
[1594,] 1991.3071 2350.3823 2279.8565 1866.2214
[1595,] 3467.7653 3851.3685 3802.4139 3416.1832
[1596,] 2044.7031 2124.0767 2173.8429 2299.5911
[1597,] 2555.2348 2752.4367 2766.0848 2703.0659
[1598,] 2008.1007 2203.9108 2203.9666 2092.2737
[1599,] 2247.9122 2407.6914 2430.9342 2416.8079
[1600,] 1748.5299 1965.8761 1947.8766 1769.0048
[1601,] 2886.5287 3188.5752 3165.4825 2922.0140
[1602,] 2532.9151 2701.1708 2726.3976 2720.3391
[1603,] 1367.1517 1631.0809 1574.0336 1267.0262
[1604,] 1575.3719 1888.5031 1821.4487 1457.9060
[1605,] 3659.1587 3905.5408 3912.6678 3803.2932
[1606,] 2638.9948 3044.5429 2972.7698 2514.6678
[1607,] 2413.7605 2879.2098 2775.6617 2198.7521
[1608,] 1228.3397 1441.6614 1400.7585 1162.2685
[1609,] 2619.2462 2766.9536 2802.0075 2839.1832
[1610,] 2873.7761 3061.4737 3085.8828 3062.3311
[1611,] 2274.2150 2417.6952 2447.9458 2469.8184
[1612,] 2236.9827 2504.3874 2481.6249 2255.3496
[1613,] 2005.7018 1797.5006 1958.5886 2742.0253
[1614,] 2667.4923 3075.3648 3002.4142 2540.6602
[1615,] 2293.1344 2556.9331 2536.9073 2322.7639
[1616,] 6567.0389 6782.5037 6785.4602 6675.5114
[1617,] 1600.4988 1876.7462 1827.0623 1526.4728
[1618,] 4169.8368 4442.7790 4435.3836 4255.7806
[1619,] 1890.5047 2118.0646 2100.7971 1917.3195
[1620,] 2182.4818 2384.9024 2387.4735 2280.2536
[1621,] 1816.0294 1857.0869 1914.5768 2095.1744
[1622,] 2553.5676 3001.8037 2909.5448 2372.3473
[1623,] 1765.0507 2035.0699 1995.9475 1720.6901
[1624,] 2359.3174 2544.0996 2558.5267 2502.7809
[1625,] 1342.3490 1469.5638 1470.2745 1399.9633
[1626,] 1132.8461 1279.7171 1263.1440 1129.5207
[1627,] 792.0149 823.0062 835.5670 860.9641
[1628,] 2099.6026 2354.3988 2332.4133 2118.8294
[1629,] 2325.3777 2650.6853 2605.0736 2279.5932
[1630,] 1127.4171 1455.9496 1358.7414 942.5332
[1631,] 1387.0366 1608.1294 1570.8678 1337.4394
[1632,] 2774.8974 2753.7228 2861.2172 3264.9463
[1633,] 1928.4577 2133.4185 2126.8030 1990.1820
[1634,] 2021.4280 2252.0812 2237.9048 2060.6870
[1635,] 1717.2444 2095.9671 2007.9728 1545.9538
[1636,] 2932.1555 3154.2155 3165.6332 3076.7843
[1637,] 1317.4936 1477.1806 1463.0820 1328.4146
[1638,] 1917.3364 2085.1754 2093.7428 2027.1069
[1639,] 882.5544 1585.0364 1276.4593 561.0992
[1640,] 1945.9771 2080.0956 2103.3871 2105.4499
[1641,] 2002.5818 2200.2208 2199.3417 2083.3885
[1642,] 1721.9462 1970.7482 1938.1879 1699.1230
[1643,] 823.9349 860.6035 872.4521 892.4515
[1644,] 1382.9764 1531.3012 1525.0012 1420.6828
[1645,] 1755.6055 1731.6202 1812.3466 2130.0513
[1646,] 2316.6395 2326.3988 2413.1856 2713.6285
[1647,] 1987.6870 2288.1917 2243.0872 1932.5037
[1648,] 2354.2592 2531.5619 2548.9799 2507.8022
[1649,] 2040.7308 2161.3434 2194.2514 2235.4526
[1650,] 3215.5815 3498.5946 3489.3732 3299.4532
[1651,] 1932.4113 2024.5132 2064.5119 2152.3686
[1652,] 1318.7310 1370.7011 1401.2324 1478.6900
[1653,] 2651.9944 2962.0845 2930.1601 2653.4691
[1654,] 3754.8772 4160.7104 4102.9862 3665.5927
[1655,] 2873.5347 3254.4008 3198.2493 2804.8378
[1656,] 1612.4526 1794.0596 1785.5231 1654.3873
[1657,] 2209.7924 2300.0314 2349.6670 2470.1028
[1658,] 2188.9395 2359.6811 2375.5952 2330.3263
[1659,] 2382.5076 2694.7506 2656.3068 2358.4147
[1660,] 2192.4738 2396.4078 2398.6441 2289.2288
[1661,] 2121.6823 2503.1551 2429.7167 1987.3820
[1662,] 1287.5591 1408.8329 1409.5992 1342.9091
[1663,] 742.6502 915.9064 863.1842 651.9333
[1664,] 1636.0125 1751.0126 1771.3531 1773.5289
[1665,] 2124.0513 2308.8643 2317.0232 2239.5031
[1666,] 2797.9595 3239.4174 3154.6412 2648.3120
[1667,] 1787.9569 1925.0101 1942.3194 1921.0451
[1668,] 1893.4379 1977.6366 2019.7164 2121.4960
[1669,] 1254.4823 1373.0802 1373.7322 1308.7408
[1670,] 2122.4185 2406.5626 2372.7656 2107.6755
[1671,] 3343.4638 3728.7600 3677.5255 3291.0241
[1672,] 834.2719 836.0810 862.3490 961.4466
[1673,] 2459.1915 2480.8520 2563.8173 2848.5652
[1674,] 2489.8771 2792.4526 2760.6901 2486.0705
[1675,] 990.7912 1078.1672 1078.8292 1030.8263
[1676,] 1540.9011 1813.4464 1762.3624 1461.8194
[1677,] 1697.8900 1854.5839 1859.9899 1788.7979
[1678,] 1988.5162 2126.8161 2149.8497 2147.6221
[1679,] 1816.0062 2098.8433 2055.6302 1763.3469
[1680,] 1690.8745 2153.5663 2026.7723 1436.3247
[1681,] 502.5128 555.8579 543.0880 475.0614
[1682,] 1678.9765 1852.7854 1850.2719 1743.3959
[1683,] 2416.2781 2686.7818 2666.4806 2449.8656
[1684,] 2671.5994 2955.2278 2934.6349 2709.0620
[1685,] 1333.2633 1355.5012 1398.5873 1543.3465
[1686,] 1625.4474 1702.2004 1737.5309 1815.9109
[1687,] 2456.0734 2699.0473 2691.9046 2528.8856
[1688,] 2275.8814 2332.2693 2398.6821 2596.1853
[1689,] 1560.6261 1766.7132 1744.9572 1561.9116
[1690,] 2353.6594 2446.2150 2498.1807 2631.1192
[1691,] 1401.5265 1630.1640 1590.2956 1345.9025
[1692,] 2353.0561 2632.3011 2606.9753 2369.1138
[1693,] 817.3829 1012.5269 954.2493 713.9785
[1694,] 2034.5818 2304.1530 2273.8446 2025.7791
[1695,] 4720.9147 5162.0647 5093.2709 4626.8608
[1696,] 1823.8544 2005.0118 2005.3021 1903.1724
[1697,] 1378.2151 1572.4268 1546.3799 1358.1830
[1698,] 1376.9724 1471.9163 1487.5358 1485.8215
[1699,] 1521.8283 1731.1339 1705.8996 1511.4180
[1700,] 887.2477 942.9013 950.4906 944.0346
[1701,] 4000.2866 4240.8971 4247.8800 4141.4382
[1702,] 1513.9101 1679.8632 1672.6257 1555.1459
[1703,] 1879.3872 2113.3786 2093.0507 1896.2687
[1704,] 2640.1270 3099.2898 3004.0431 2450.5988
[1705,] 3478.3757 3664.4223 3696.3767 3700.6880
[1706,] 1481.4281 1529.8584 1569.1704 1682.2508
[1707,] 3192.6265 3440.0149 3445.4068 3323.3692
[1708,] 5175.1068 5451.2795 5458.9738 5333.8099
[1709,] 2271.8862 2543.2199 2519.5442 2289.1121
[1710,] 1579.5349 1647.3860 1683.9359 1773.5906
[1711,] 1110.1561 1329.2762 1280.4708 1023.1094
[1712,] 2856.5767 3273.9365 3202.3993 2740.4181
[1713,] 1611.8669 1685.3748 1721.3140 1804.3377
[1714,] 1001.9134 978.8354 1024.1627 1221.2289
[1715,] 1476.0640 1618.0301 1618.8664 1540.2799
[1716,] 1527.0706 1645.4809 1658.7421 1634.6008
[1717,] 1210.1873 1309.5070 1316.5291 1283.5840
[1718,] 2211.7831 2444.9901 2436.1315 2273.0192
[1719,] 2304.9027 2658.0691 2599.9731 2223.0269
[1720,] 1225.6693 1336.8988 1339.5501 1285.2033
[1721,] 1721.3127 1938.0684 1919.1831 1737.7204
[1722,] 1444.3098 1566.2221 1573.7663 1528.5186
[1723,] 1956.2320 2174.3593 2163.0052 2003.6100
[1724,] 1562.0080 1746.1834 1733.8157 1590.4497
[1725,] 1641.4140 1794.0205 1798.8198 1727.5421
[1726,] 1920.0690 2143.3430 2128.7618 1956.7590
[1727,] 1350.4192 1348.1129 1401.6574 1605.5481
[1728,] 3051.0741 3361.4417 3338.4851 3087.4605
[1729,] 1585.8607 1844.4726 1801.8348 1529.3945
[1730,] 1334.4022 1488.8731 1477.7607 1355.0163
[1731,] 1990.3434 2189.5664 2187.4441 2066.7433
[1732,] 4705.0896 5223.1279 5120.9388 4514.6446
[1733,] 2189.3811 2229.9061 2298.4974 2521.2692
[1734,] 1906.2339 2260.7956 2190.7922 1779.6522
[1735,] 1920.4827 2734.1647 2460.7928 1366.7630
[1736,] 2962.6691 3264.0881 3243.6307 3003.2002
[1737,] 1457.4142 1646.2673 1626.3253 1458.5320
[1738,] 999.0916 1217.3236 1161.6609 899.3038
[1739,] 581.8211 502.0827 543.9942 858.3344
[1740,] 1546.2153 1749.4140 1728.1108 1548.0341
[1741,] 1829.3505 2301.8047 2177.2697 1570.3091
[1742,] 3223.5476 3560.5825 3530.3743 3234.0624
[1743,] 2139.3355 2468.3037 2417.0537 2069.6940
[1744,] 1599.5826 1946.5096 1865.4940 1450.9695
[1745,] 4186.9439 4603.2374 4535.1032 4074.5345
[1746,] 1887.8193 1957.0360 2005.5524 2137.0286
[1747,] 650.4087 706.4621 699.1672 647.1321
[1748,] 2132.8701 2282.7657 2305.6110 2297.5987
[1749,] 1269.5681 1545.9088 1478.9504 1141.4935
[1750,] 2142.4921 2286.9702 2312.3231 2315.9486
[1751,] 1693.2856 2102.1901 2000.0288 1489.9024
[1752,] 2513.7157 2823.1798 2788.9000 2503.3090
[1753,] 1317.3158 1471.9714 1460.0002 1334.5054
[1754,] 2005.4299 2182.6922 2190.5060 2114.2866
[1755,] 1498.4359 1601.4413 1619.5533 1621.1301
[1756,] 4441.5169 4831.6593 4776.4272 4382.1977
[1757,] 1630.8980 1894.4057 1851.5932 1575.9616
[1758,] 1508.8513 1616.2977 1633.1250 1627.6229
[1759,] 1685.2144 1837.1962 1844.0434 1780.4436
[1760,] 1128.7412 1199.2663 1214.4226 1225.2856
[1761,] 1861.1285 2027.7285 2035.1810 1966.6045
[1762,] 2229.0008 2478.2130 2462.9821 2270.6071
[1763,] 1462.6717 1567.8193 1583.2137 1574.2190
[1764,] 2116.4035 2373.3960 2350.9946 2135.2172
[1765,] 1473.2372 1658.3020 1640.8160 1482.1556
[1766,] 2050.7296 2429.5327 2352.2966 1913.1574
[1767,] 830.2995 874.1207 883.3046 889.5221
[1768,] 1591.5434 1291.4766 1463.5623 2543.8489
[1769,] 1507.1318 1586.0196 1614.3939 1667.1190
[1770,] 4003.8193 4373.4721 4326.0210 3959.3516
[1771,] 1482.2676 1636.8423 1632.7230 1531.3542
[1772,] 854.9551 868.3800 891.0722 967.3674
[1773,] 660.8391 648.5036 669.6699 766.0804
[1774,] 1299.6818 1379.0719 1397.5800 1414.8456
[1775,] 2177.6737 2354.2248 2367.4043 2309.9002
[1776,] 1708.7862 1897.0550 1889.6983 1759.5459
[1777,] 1540.7166 1753.2139 1727.6355 1530.3123
[1778,] 2036.4952 2217.6338 2224.6751 2145.5413
[1779,] 1423.1900 1508.1883 1529.9317 1555.2977
[1780,] 1025.6533 1168.5547 1147.7851 1006.1611
[1781,] 1194.2177 1606.5703 1473.5568 945.6618
[1782,] 1269.3264 1454.6481 1427.6326 1241.1769
[1783,] 3386.0854 3729.4452 3695.9658 3391.7287
[1784,] 1717.7495 1898.7932 1894.8420 1779.6497
[1785,] 1652.5101 1788.9211 1800.8872 1763.3611
[1786,] 2213.7202 2588.9230 2519.1625 2092.5130
[1787,] 1739.4250 1972.1282 1947.2064 1739.1417
[1788,] 772.7846 870.0041 853.7050 751.4937
[1789,] 3126.7314 3476.0240 3437.5970 3117.7949
[1790,] 1342.2442 1476.2368 1474.1072 1390.8241
[1791,] 983.9940 1111.6531 1094.8526 973.1367
[1792,] 2383.7398 2529.9394 2560.7287 2582.8656
[1793,] 934.6815 982.5300 996.1730 1014.6807
[1794,] 2077.5680 2328.8654 2307.6853 2098.1292
[1795,] 1081.4551 1161.4927 1170.4742 1154.3504
[1796,] 888.0726 922.3756 938.7251 976.5114
[1797,] 2221.6032 2704.8726 2588.1087 1977.9722
[1798,] 1694.0202 1803.5792 1828.2476 1850.1112
[1799,] 1722.1245 1770.6726 1821.1350 1976.0945
[1800,] 742.9954 693.2183 733.0807 957.1427
[1801,] 1502.5781 1730.3936 1696.1452 1466.8550
[1802,] 1763.0698 1919.2057 1927.5002 1865.1438
[1803,] 857.5677 869.1721 892.7448 973.8635
[1804,] 515.8733 520.6148 528.6414 554.4225
[1805,] 1938.9988 2207.6605 2174.6283 1919.5511
[1806,] 1267.4132 1399.7811 1395.1463 1305.4849
[1807,] 1162.9186 1321.3295 1301.6693 1150.8364
[1808,] 1772.2992 1949.1782 1949.2115 1848.1280
[1809,] 2113.9753 2237.0084 2270.2797 2315.4096
[1810,] 1350.2415 1483.9383 1482.2942 1400.7682
[1811,] 1070.9154 1370.3119 1283.4824 908.5072
[1812,] 951.2327 945.5448 981.0751 1125.1364
[1813,] 1548.0373 1619.1030 1652.7396 1729.5647
[1814,] 1247.7765 1399.3847 1385.8750 1257.7539
[1815,] 2324.8160 2527.0760 2533.5511 2442.6507
[1816,] 1507.5852 1675.1019 1666.8709 1545.4884
[1817,] 1218.6293 1304.8111 1317.5649 1312.0716
[1818,] 2847.6959 3003.6116 3040.5190 3079.9407
[1819,] 1360.3482 1490.3032 1490.6810 1417.8303
[1820,] 4187.7837 4694.6501 4587.4492 3948.0077
[1821,] 947.1760 1143.0296 1093.5810 860.3643
[1822,] 1252.4158 1320.1767 1341.6947 1377.5924
[1823,] 2899.6229 3320.4576 3249.1030 2779.6111
[1824,] 2271.6579 2534.1915 2514.2444 2300.4802
[1825,] 2322.0876 2572.9309 2558.9905 2372.4653
[1826,] 1649.4671 1802.0949 1807.2144 1737.0894
[1827,] 4503.6418 4222.9687 4447.6633 5455.9652
[1828,] 956.4035 1389.2553 1229.2312 709.1443
[1829,] 1081.6959 1234.2497 1212.6571 1062.0836
[1830,] 1973.5010 2085.2359 2118.4368 2168.1461
[1831,] 717.5553 731.6809 745.9316 791.9816
[1832,] 2302.5337 2742.1866 2648.3499 2113.7768
[1833,] 5291.6876 5631.5464 5612.4949 5360.0613
[1834,] 1277.1943 1405.0380 1402.6689 1322.4744
[1835,] 1902.1258 2141.7981 2119.7310 1914.9076
[1836,] 3394.0646 3376.7633 3496.5030 3905.9250
[1837,] 2626.3301 2922.1142 2895.5636 2644.8916
[1838,] 1273.8572 1584.1743 1502.0016 1113.1191
[1839,] 1415.9882 1805.1858 1694.2717 1201.8438
[1840,] 704.6279 688.0844 713.6133 832.8333
[1841,] 3265.4418 3294.9564 3390.8839 3707.2791
[1842,] 1226.3697 1430.4422 1393.4940 1170.3835
[1843,] 1443.6630 1599.4603 1592.8136 1482.9890
[1844,] 970.6321 1301.0019 1191.2298 782.8212
[1845,] 883.5876 872.6537 906.5769 1048.2493
[1846,] 1485.6262 1632.1652 1631.5891 1545.8963
[1847,] 1095.8176 1168.7270 1181.3297 1181.8639
[1848,] 945.3222 1090.0474 1063.1111 907.6925
[1849,] 2930.2892 3222.6723 3204.6031 2982.0869
[1850,] 2895.3291 3109.8271 3123.6097 3048.0363
[1851,] 2736.2534 2667.4296 2792.3799 3296.9889
[1852,] 5141.0946 5531.9033 5491.4401 5136.3273
[1853,] 1200.2103 1288.9010 1300.1146 1286.4798
[1854,] 2560.2099 2598.7942 2679.8378 2937.4207
[1855,] 1359.0589 1330.2048 1394.4153 1663.4745
[1856,] 1285.7361 1467.1439 1442.5028 1264.6000
[1857,] 1821.6594 1921.0509 1955.4846 2015.1723
[1858,] 4001.8724 4173.3338 4208.9406 4239.5313
[1859,] 1783.7939 1877.5847 1912.3298 1978.5870
[1860,] 1111.7291 1198.4124 1206.1039 1181.8291
[1861,] 1381.3888 1437.6167 1469.1704 1548.4116
[1862,] 635.7489 677.1973 675.1513 644.8644
[1863,] 600.3925 618.2544 623.7483 631.8668
[1864,] 869.6019 879.5085 904.5902 992.2839
[1865,] 881.4377 967.3440 962.0111 896.3853
[1866,] 1228.0521 1388.9109 1370.7038 1223.2760
[1867,] 1103.1324 1268.5441 1242.4872 1072.5188
[1868,] 3524.1793 3906.6384 3857.3972 3467.0051
[1869,] 792.2560 794.6258 818.3381 907.8375
[1870,] 1940.3787 2119.5006 2124.0389 2037.1320
[1871,] 1049.0355 1236.9092 1198.0636 985.4943
[1872,] 2816.9563 3091.1925 3078.3258 2881.7524
[1873,] 1043.6470 1110.2031 1122.6394 1126.0237
[1874,] 2500.2017 2845.9489 2795.8703 2442.4517
[1875,] 1187.8611 1329.5550 1317.9731 1200.6001
[1876,] 1970.7601 2170.2552 2167.1527 2043.4011
[1877,] 1133.9310 1219.5495 1228.7589 1210.1863
[1878,] 1743.0777 2113.1417 2029.6034 1582.7308
[1879,] 1003.7857 1020.2327 1050.2148 1153.0068
[1880,] 1298.5653 1465.2975 1447.3666 1297.4121
[1881,] 1327.1480 1417.0610 1432.6074 1433.1771
[1882,] 1573.5281 1514.0857 1599.8386 1982.5228
[1883,] 937.7605 1101.3289 1065.4810 879.2864
[1884,] 747.8959 762.8843 779.6218 831.6004
[1885,] 1421.0315 1380.5648 1452.1003 1761.0455
[1886,] 1440.4354 1413.7106 1480.6123 1759.3888
[1887,] 963.5292 1056.2572 1053.1646 990.4004
[1888,] 1568.1744 1783.1484 1758.0844 1560.1984
[1889,] 1775.1582 1916.7133 1931.5295 1899.1976
[1890,] 818.9513 923.8750 906.8510 798.6520
[1891,] 2425.6066 2635.6345 2640.8900 2538.0630
[1892,] 658.3136 724.7229 713.6705 645.6627
[1893,] 1867.4524 2086.3236 2072.0512 1902.3340
[1894,] 725.2047 870.8646 829.4109 653.0348
[1895,] 1565.1716 1563.3759 1626.6910 1868.0095
[1896,] 1323.1892 1460.1074 1455.8886 1364.2430
[1897,] 1039.0755 1210.1389 1178.0353 991.2644
[1898,] 942.5815 993.3106 1006.2751 1020.8164
[1899,] 2434.6917 2758.4362 2716.6196 2396.0437
[1900,] 2556.5605 2807.7642 2798.8958 2628.5828
[1901,] 2850.1457 3090.4903 3092.5540 2965.0734
[1902,] 3653.2194 4075.9406 4008.4472 3548.8385
[1903,] 1407.7579 1427.9584 1475.0778 1637.7493
[1904,] 1696.9198 2040.5865 1967.2949 1561.1920
[1905,] 1291.7124 1562.3964 1498.7705 1171.7711
[1906,] 1760.7181 2032.8294 1992.7161 1713.3538
[1907,] 1511.2085 1544.1937 1591.1336 1744.0871
[1908,] 1716.9149 1899.1541 1894.6669 1777.1254
[1909,] 940.7111 1169.4031 1104.5006 824.5272
[1910,] 1762.0723 2106.8080 2034.9446 1630.5271
[1911,] 2055.5949 2244.4787 2248.8784 2156.7346
[1912,] 1038.3498 1251.0520 1200.4849 948.6880
[1913,] 5123.5566 5587.3826 5515.8641 5020.0099
[1914,] 983.1804 1179.4347 1132.5435 901.6480
[1915,] 699.2159 716.3189 728.7253 763.8698
[1916,] 683.1445 646.4705 677.6457 851.7028
[1917,] 2869.9137 3134.4081 3126.7866 2954.1778
[1918,] 3230.8470 3668.5743 3595.0183 3098.9741
[1919,] 1301.7475 1482.3026 1458.5614 1283.9282
[1920,] 1334.3959 1589.9732 1535.0428 1237.1677
[1921,] 946.2906 970.1324 994.1982 1066.5480
[1922,] 1162.8858 1300.8280 1289.5720 1176.3405
[1923,] 1383.1684 1402.3909 1449.0037 1609.2602
[1924,] 1800.9163 1788.0615 1865.8528 2164.8868
[1925,] 2647.9196 2845.6677 2860.5805 2798.0292
[1926,] 814.0502 891.7205 886.0587 824.6876
[1927,] 2311.7066 2479.4534 2499.9517 2476.2810
[1928,] 1749.8484 1934.6600 1930.4492 1811.8362
[1929,] 446.7470 556.1671 516.6130 363.5949
[1930,] 1307.9718 1393.4838 1409.8785 1416.0267
[1931,] 1817.6132 2005.2657 2002.6526 1887.0382
[1932,] 1342.2702 1575.0676 1530.5598 1271.4697
[1933,] 1144.9452 1160.4551 1198.4926 1329.6215
[1934,] 4982.8455 5270.0079 5271.6913 5114.7017
[1935,] 1150.5174 1288.1095 1276.3797 1161.9649
[1936,] 1927.1262 2066.8977 2087.3347 2076.7260
[1937,] 1216.0025 1211.1830 1260.5902 1448.4608
[1938,] 2753.1604 3146.1701 3081.1430 2657.2715
[1939,] 911.9605 998.3286 994.5768 933.5848
[1940,] 1425.5306 1505.3357 1529.2966 1565.7221
[1941,] 1970.4662 1762.0296 1920.9751 2704.6488
[1942,] 2931.0452 2679.1943 2880.8304 3798.8010
[1943,] 1039.5708 1219.4840 1183.5330 982.4878
[1944,] 1076.2443 1031.4868 1088.9962 1354.8913
[1945,] 1242.7524 1354.0295 1357.2971 1305.1108
[1946,] 867.7122 1002.9129 975.1152 824.3050
[1947,] 1572.5291 2044.7651 1906.9647 1302.8355
[1948,] 1397.4588 1765.5391 1662.9736 1200.1551
[1949,] 1656.2003 1847.5952 1836.7435 1693.3376
[1950,] 966.1028 1153.4830 1109.4260 890.6137
[1951,] 788.0003 862.0475 856.5210 797.1275
[1952,] 854.0292 1030.7648 983.3922 768.9631
[1953,] 2175.7244 2311.1618 2341.1920 2365.6964
[1954,] 1646.4616 1943.3893 1886.6569 1556.5700
[1955,] 1317.9658 1430.3801 1436.1836 1390.6820
[1956,] 485.2671 517.8282 513.5841 481.6624
[1957,] 1066.2836 1129.7487 1144.7906 1159.4663
[1958,] 2165.3722 2404.4677 2391.1363 2213.8618
[1959,] 1112.8669 1077.2326 1133.5689 1379.7798
[1960,] 1844.2356 2045.7338 2038.1001 1898.8441
[1961,] 819.8620 878.9015 881.3653 855.7672
[1962,] 1039.6284 1208.8799 1177.6032 993.8700
[1963,] 1027.1572 1047.2606 1077.1974 1176.2293
[1964,] 1884.0149 2058.9185 2063.5852 1981.0539
[1965,] 1458.1040 1569.8004 1582.2681 1559.4404
[1966,] 2950.9672 3141.5211 3166.3678 3140.3348
[1967,] 764.1803 788.7071 802.2373 836.4172
[1968,] 873.2631 916.1637 928.2390 944.8062
[1969,] 1305.0459 1379.5752 1400.3086 1428.3820
[1970,] 1160.0116 1161.2002 1205.5684 1371.2295
[1971,] 2007.7501 2078.6654 2129.9638 2268.6152
[1972,] 654.8530 690.7158 692.4027 677.6350
[1973,] 1263.5413 1305.6226 1337.8956 1429.6449
[1974,] 1298.4372 1343.0915 1375.5986 1465.4943
[1975,] 972.0839 1060.4757 1059.6649 1006.6130
[1976,] 2556.4094 2754.8652 2768.0130 2702.5601
[1977,] 1217.9264 1352.2966 1344.9552 1245.1067
[1978,] 1457.3009 1481.3089 1529.1144 1691.9639
[1979,] 1883.1153 2073.8534 2071.8825 1958.1812
[1980,] 2220.3462 2577.3909 2515.7090 2122.1848
[1981,] 1946.7992 2055.6310 2089.2620 2143.1132
[1982,] 2460.4631 2679.0658 2682.2167 2567.4020
[1983,] 1826.5686 1949.0593 1974.3525 1988.7209
[1984,] 4505.9381 4901.6648 4845.9155 4448.1728
[1985,] 1566.5979 1901.0877 1824.1158 1425.8976
[1986,] 2076.2449 2169.2410 2214.2506 2316.7317
[1987,] 4006.4244 4282.2789 4274.4274 4097.4485
[1988,] 1600.9566 1719.5936 1736.6182 1725.2004
[1989,] 1475.3647 1681.4277 1655.0780 1459.5525
[1990,] 1894.5584 2120.3138 2103.9310 1924.3138
[1991,] 954.0283 1050.3948 1045.1481 973.4649
[1992,] 1908.5738 1880.5759 1969.6959 2312.4724
[1993,] 991.5248 1324.9439 1215.6310 801.3404
[1994,] 1104.3180 1233.5023 1223.0312 1117.1212
[1995,] 1093.2493 1232.2110 1217.0272 1091.9067
[1996,] 1691.9681 1994.3731 1937.7382 1601.9016
[1997,] 1534.0481 1735.1136 1714.0639 1535.9552
[1998,] 984.9097 1184.1665 1136.0514 900.7808
[1999,] 1436.5367 1763.4950 1681.7365 1284.1150
[2000,] 1104.0638 1243.3287 1228.5566 1104.4225
[2001,] 1021.0069 1056.6821 1080.1884 1143.1464
[2002,] 1528.2717 1779.6995 1736.6472 1470.8217
[2003,] 1331.0372 1582.5580 1529.2594 1237.5498
[2004,] 2076.3467 2192.4822 2227.5195 2283.6255
[2005,] 1874.2730 2162.8291 2118.9445 1822.7322
[2006,] 1219.1604 1376.4481 1359.4255 1217.3815
[2007,] 1308.2477 1507.4776 1475.9834 1269.3182
[2008,] 898.2748 995.1963 986.1121 903.8688
[2009,] 1979.6649 2358.1750 2278.6852 1830.3891
[2010,] 1102.2261 1325.9714 1274.6240 1009.7303
[2011,] 425.8011 457.5138 452.1289 417.6207
[2012,] 2179.1498 2422.4746 2407.7731 2223.6029
[2013,] 1269.5846 1403.9685 1398.5672 1305.3612
[2014,] 1397.0498 1481.4825 1502.2941 1524.9024
[2015,] 1215.2469 1334.1192 1333.1898 1262.5428
[2016,] 1358.6451 1412.5492 1444.2170 1524.2769
[2017,] 1525.4141 1794.8653 1743.9961 1447.3781
[2018,] 2461.3570 2739.6564 2717.7043 2486.6616
[2019,] 1200.4788 1254.8623 1280.0709 1335.8959
[2020,] 1188.3048 1334.6631 1321.1164 1195.2069
[2021,] 1613.0396 1723.2235 1744.3406 1752.1078
[2022,] 1346.7577 1557.2549 1522.6908 1302.3660
[2023,] 840.3681 963.0888 939.5899 804.1121
[2024,] 1528.2088 1738.9404 1713.4404 1517.3870
[2025,] 1436.4303 1611.6416 1596.4181 1450.0116
[2026,] 1204.0606 1397.5804 1364.3490 1156.7837
[2027,] 1049.1321 1203.7507 1179.4351 1021.3511
[2028,] 1518.8923 1662.7437 1665.0309 1589.9611
[2029,] 1058.1110 1174.3036 1166.9610 1077.7506
[2030,] 1376.6206 1382.5441 1434.1667 1623.5214
[2031,] 1179.5218 1329.2747 1313.9456 1180.7445
[2032,] 7221.6253 7457.5529 7453.4921 7307.2255
[2033,] 2046.9897 2168.5070 2201.1013 2241.5412
[2034,] 2542.3252 2821.9226 2800.8351 2574.1511
[2035,] 917.9471 926.3967 954.3820 1056.4899
[2036,] 755.6965 828.2501 821.5305 760.0325
[2037,] 1493.9596 1696.9928 1672.9425 1485.4204
[2038,] 1072.0411 1142.3656 1154.8808 1156.6053
[2039,] 1357.0621 1544.4899 1520.3697 1341.3392
[2040,] 4385.4351 4403.3460 4501.0822 4844.9211
[2041,] 1647.9897 1551.7892 1655.0573 2137.2447
[2042,] 1449.6442 1474.5845 1521.6435 1680.9172
[2043,] 1016.5997 1239.9377 1183.1555 914.3776
[2044,] 755.9731 711.3666 749.8019 959.7783
[2045,] 1307.6783 1413.2317 1421.3620 1387.5374
[2046,] 674.5438 745.3075 733.5872 660.0350
[2047,] 826.3874 864.6561 875.9521 893.0314
[2048,] 1509.1392 1678.9674 1669.8438 1544.4422
[2049,] 4206.9042 4458.1127 4459.9061 4325.6435
[2050,] 894.8882 876.2550 913.7150 1077.0357
[2051,] 1009.3004 1058.6563 1075.9820 1107.2054
[2052,] 2381.8382 2505.4789 2545.4296 2613.8493
[2053,] 1429.3354 1543.3454 1553.4578 1521.4207
[2054,] 843.3354 873.6134 888.9916 926.0067
[2055,] 624.3433 619.1134 635.0611 702.5330
[2056,] 1378.3244 1570.1243 1545.1192 1361.1760
[2057,] 1106.0971 1159.3167 1180.4459 1223.1580
[2058,] 1508.9809 1993.8805 1845.3941 1223.3089
[2059,] 1046.8811 958.6783 1030.2008 1412.5657
[2060,] 972.6173 1224.2110 1151.5480 842.1513
[2061,] 1430.7808 1538.5039 1551.2753 1531.8746
[2062,] 962.7939 1000.5919 1020.0870 1066.6993
[2063,] 1091.3922 1072.1414 1121.1885 1324.3683
[2064,] 719.6641 747.4853 756.8938 772.2989
[2065,] 1533.3129 1636.5208 1656.3485 1663.7832
[2066,] 2042.4415 2174.0620 2202.2523 2222.1507
[2067,] 692.0535 698.4281 714.7330 771.7181
[2068,] 696.1517 743.6050 743.3782 715.6602
[2069,] 945.7066 1220.7928 1134.8871 794.2737
[2070,] 964.6769 987.7082 1013.2508 1092.8773
[2071,] 1049.6663 1159.7995 1154.4896 1074.7729
[2072,] 731.0531 768.8246 775.0325 773.5675
[2073,] 1367.5372 1254.9690 1351.5976 1839.5919
[2074,] 1274.9235 1392.7005 1394.4563 1333.1447
[2075,] 1081.3562 1232.0255 1211.2271 1063.8401
[2076,] 1027.1216 1116.5482 1118.5363 1073.2676
[2077,] 1165.7232 1302.5623 1291.9376 1181.0590
[2078,] 635.1845 642.6565 653.9722 693.3294
[2079,] 810.2545 894.1486 885.6109 812.3536
[2080,] 1179.1309 1256.2304 1271.1475 1277.1566
[2081,] 1328.7264 1456.2718 1456.2308 1383.2315
[2082,] 1005.0827 1045.1846 1065.8006 1116.2494
[2083,] 802.8873 898.9035 884.6540 789.3207
[2084,] 1505.3802 1754.9285 1711.3978 1445.8057
[2085,] 1639.9612 1737.8513 1765.3781 1802.5657
[2086,] 977.5028 1007.5393 1030.9007 1097.7775
[2087,] 537.0324 537.9871 548.0725 583.8859
[2088,] 1026.1494 1191.2787 1160.9207 982.1432
[2089,] 1488.9211 1683.1226 1662.5783 1489.9416
[2090,] 579.8808 555.3653 576.6355 684.2120
[2091,] 1245.6302 1340.1861 1350.4885 1331.2786
[2092,] 653.5980 597.6124 633.2012 875.7214
[2093,] 2780.4585 3343.1092 3208.3673 2478.9046
[2094,] 1260.1922 1430.6988 1409.5967 1248.6740
[2095,] 1100.7156 1061.2969 1118.4366 1372.4872
[2096,] 1971.6124 2205.3350 2188.0981 2000.1560
[2097,] 1701.3306 2049.6788 1974.7720 1560.9018
[2098,] 993.6610 1086.3971 1084.9886 1027.4674
[2099,] 947.0506 1007.7645 1016.9191 1012.3405
[2100,] 1592.5918 1885.8730 1828.3669 1498.6942
[2101,] 3022.7101 3362.1569 3326.4534 3017.8334
[2102,] 820.9152 964.7588 930.8221 760.4412
[2103,] 936.9564 983.5143 997.8262 1019.5516
[2104,] 826.2543 1108.9381 1009.0654 666.5351
[2105,] 798.4794 919.8409 894.2716 756.6035
[2106,] 721.6590 756.7288 763.3530 764.4755
[2107,] 1995.9282 2293.1521 2249.7311 1946.4370
[2108,] 755.1189 724.5832 758.2974 926.8035
[2109,] 1090.4267 1303.0659 1255.6581 1008.0481
[2110,] 2513.3016 2766.1276 2755.8430 2578.5564
[2111,] 866.1565 874.2469 899.7701 991.0366
[2112,] 2837.9352 3280.5240 3197.8293 2689.9016
[2113,] 986.8094 1022.9591 1044.2890 1099.6579
[2114,] 1061.4558 1117.8113 1135.4823 1163.7940
[2115,] 900.5958 1031.5567 1007.9976 868.2554
[2116,] 984.4643 1028.2306 1046.3760 1084.8484
[2117,] 1571.8810 1880.9097 1815.5163 1458.2064
[2118,] 1115.2355 1240.4518 1232.2035 1135.1637
[2119,] 888.0185 1014.1319 991.8548 858.6373
[2120,] 1147.6758 1313.2654 1289.6102 1124.5995
[2121,] 3117.3248 3482.9580 3437.4275 3086.3113
[2122,] 957.1006 1219.0572 1140.3140 816.6273
[2123,] 1228.0647 1299.0700 1318.4163 1344.6975
[2124,] 2067.0439 2435.2183 2363.2791 1944.4483
[2125,] 1563.0710 1611.3899 1654.9087 1783.5977
[2126,] 813.4462 926.4134 905.5921 783.5782
[2127,] 1771.8071 1936.5231 1941.6089 1863.7046
[2128,] 906.6495 966.5267 973.4751 961.2394
[2129,] 649.4705 747.9116 722.0839 605.4981
[2130,] 2184.5226 2416.4110 2406.6935 2244.0386
[2131,] 649.7008 676.5612 681.6955 683.6708
[2132,] 602.4874 725.8968 683.3544 528.9523
[2133,] 1100.6577 1167.4257 1182.7759 1196.5643
[2134,] 2268.2691 2297.7603 2374.4354 2628.6571
[2135,] 1698.0563 1910.2710 1892.3436 1716.0798
[2136,] 937.8068 1248.5988 1145.0921 760.8657
[2137,] 1080.6310 1254.9947 1223.8965 1036.6728
[2138,] 856.2552 885.8678 902.4027 942.9770
[2139,] 1432.7414 1551.0907 1559.5617 1519.4997
[2140,] 985.6686 1076.4085 1075.3586 1020.1845
[2141,] 623.2098 655.5570 656.3415 640.1432
[2142,] 4819.6810 4980.5087 5031.5004 5115.8436
[2143,] 2123.6353 2048.8832 2162.5925 2634.6681
[2144,] 1434.3626 1511.4728 1536.9206 1580.2772
[2145,] 940.6716 1090.2663 1060.8862 896.8778
[2146,] 1244.0393 1351.0326 1356.1290 1312.3603
[2147,] 629.2836 592.5048 619.9937 784.3436
[2148,] 1871.9223 2198.1541 2137.8661 1776.1059
[2149,] 899.7131 759.8076 839.6190 1396.9174
[2150,] 940.9352 1075.5700 1052.9336 912.9491
[2151,] 2605.3114 2790.4994 2809.9322 2771.4781
[2152,] 1146.9632 1329.8467 1298.9414 1103.5281
[2153,] 1497.6525 1664.8887 1656.2509 1533.8096
[2154,] 1656.9763 1572.5525 1671.9321 2124.8482
[2155,] 855.8073 927.0505 926.4286 883.3896
[2156,] 1325.1221 1595.8109 1533.7051 1210.3231
[2157,] 1143.2102 1248.8484 1250.2061 1194.1715
[2158,] 1251.0185 1325.4605 1344.2088 1366.1570
[2159,] 1398.8974 1313.7840 1401.1073 1821.4803
[2160,] 1450.6999 1606.7129 1600.3370 1491.2329
[2161,] 4538.6337 4773.3225 4786.3317 4696.8751
[2162,] 1273.9624 1333.6728 1359.2370 1414.4431
[2163,] 1238.8312 1308.7454 1328.8917 1358.7824
[2164,] 1451.8579 1567.1219 1577.8005 1546.8560
[2165,] 531.1707 555.1245 555.6176 543.7115
[2166,] 1117.1037 1180.6054 1198.0674 1221.3485
[2167,] 1580.5621 1637.7161 1678.6063 1791.1723
[2168,] 1137.5922 1276.0226 1263.2871 1145.4662
[2169,] 5524.2324 5958.2548 5896.7864 5443.0635
[2170,] 1145.9600 1318.3677 1291.7641 1114.5486
[2171,] 804.3933 915.4737 894.8273 774.6396
[2172,] 604.7189 905.7942 768.3859 440.6387
[2173,] 604.0743 612.3744 621.8875 651.0801
[2174,] 2345.6877 2620.6135 2596.9699 2366.5992
[2175,] 1557.6828 1574.1567 1629.9695 1828.1509
[2176,] 966.0740 1005.6243 1024.6197 1068.4119
[2177,] 1647.4997 1885.3790 1854.3535 1625.2718
[2178,] 867.1519 848.8427 884.3244 1041.1038
[2179,] 1640.0994 1541.1667 1645.0321 2133.5883
[2180,] 1154.7900 1227.8615 1243.2372 1253.2973
[2181,] 880.2805 1005.4919 983.0469 850.2587
[2182,] 1290.5979 1911.8608 1682.5267 905.8711
[2183,] 1035.2866 1093.8014 1109.0251 1126.8993
[2184,] 1153.1811 1225.6054 1241.1676 1252.2731
[2185,] 1563.3401 1645.3806 1675.3732 1731.9315
[2186,] 808.8013 957.4863 920.6189 742.3184
[2187,] 1147.6744 1131.5821 1182.1037 1386.1203
[2188,] 1212.9806 1401.6124 1370.8571 1172.6723
[2189,] 808.0545 900.0451 887.8961 800.2531
[2190,] 1972.9752 2170.1053 2168.0567 2048.9046
[2191,] 516.7586 567.8875 556.4539 493.3070
[2192,] 1775.7941 2044.2760 2006.0308 1734.4143
[2193,] 861.0930 950.1302 942.3131 867.5171
[2194,] 1406.2079 1818.0141 1696.2345 1171.0018
[2195,] 676.5492 732.5058 727.2473 679.4576
[2196,] 1529.3795 1457.6287 1545.7851 1953.3202
[2197,] 1497.9771 1610.9963 1624.9717 1606.4075
[2198,] 971.0913 1057.2839 1057.3463 1008.3305
[2199,] 796.6568 873.0634 867.0351 804.6842
[2200,] 771.8809 774.7156 797.2445 881.3105
[2201,] 713.1989 764.6507 763.8476 731.7513
[2202,] 1438.3659 1593.2808 1586.7400 1477.7466
[2203,] 1791.6359 2024.5479 2002.0268 1797.4556
[2204,] 999.0101 1083.0385 1085.5862 1045.3306
[2205,] 2113.3840 2176.7504 2234.5450 2404.6770
[2206,] 3124.3795 3601.1446 3512.1893 2947.2026
[2207,] 1475.2069 1601.9340 1609.0684 1559.6382
[2208,] 447.7081 479.8334 474.8914 441.2084
[2209,] 783.3726 864.7682 855.8607 782.6125
[2210,] 1810.3912 1932.8266 1957.2995 1969.4397
[2211,] 1083.2695 1357.5961 1282.8387 942.1780
[2212,] 1284.3055 1544.6392 1485.3728 1174.2280
[2213,] 1605.8477 1737.8900 1749.6471 1712.5000
[2214,] 1198.4404 971.7303 1097.8650 1947.3325
[2215,] 996.0468 1080.0224 1082.4154 1041.7391
[2216,] 729.0379 831.5272 809.7296 694.7086
[2217,] 1225.1759 1316.4192 1327.3320 1312.4576
[2218,] 1039.5771 1147.3154 1142.3920 1065.0810
[2219,] 810.6966 920.9254 901.1142 783.2711
[2220,] 1106.3644 1214.8412 1213.2013 1146.0153
[2221,] 1044.9586 1291.2284 1225.9674 925.8441
[2222,] 1197.7741 1269.0513 1287.2757 1308.2162
[2223,] 1368.9414 1420.0027 1453.2106 1541.1671
[2224,] 1226.2704 1693.9896 1535.7178 939.0007
[2225,] 1343.6784 1531.7035 1506.7027 1324.8714
[2226,] 1349.0793 1368.8008 1413.6551 1566.7766
[2227,] 637.7777 622.0180 642.5158 742.6590
[2228,] 1950.2099 2161.8442 2153.0519 2005.3272
[2229,] 1097.9023 1184.9811 1191.8393 1164.5441
[2230,] 1383.8061 1339.2756 1410.6706 1723.1246
[2231,] 832.0811 928.3953 915.8195 823.8656
[2232,] 769.7612 849.6719 840.6196 768.0337
[2233,] 1527.6598 1841.1461 1771.6083 1402.7295
[2234,] 874.0334 937.4649 941.1287 916.7684
[2235,] 1935.7143 2192.0425 2163.8687 1931.9638
[2236,] 688.7059 756.3904 746.7022 681.6573
[2237,] 1873.1731 2460.8717 2285.4353 1508.3020
[2238,] 672.3422 700.4990 706.5429 709.8220
[2239,] 713.5711 762.2840 762.6539 735.6030
[2240,] 702.5354 769.1096 761.1297 700.4167
[2241,] 1226.3828 1493.6257 1429.0569 1102.8507
[2242,] 656.7695 640.8696 662.8141 769.5382
[2243,] 2914.4806 2969.4125 3048.4997 3300.4722
[2244,] 1661.9726 2008.4834 1931.3994 1520.3523
[2245,] 865.3880 1020.8875 983.9485 801.5388
[2246,] 907.7447 1037.5672 1014.9732 877.8666
[2247,] 1018.0209 1103.6285 1106.6577 1066.8341
[2248,] 965.2123 1040.6289 1044.8753 1015.6053
[2249,] 744.7926 770.6775 782.7778 809.9273
[2250,] 1826.7706 1847.3092 1913.4250 2140.2967
[2251,] 727.2727 914.9071 853.9248 626.7666
[2252,] 1719.8255 1885.9395 1888.3187 1801.6361
[2253,] 397.3070 404.8593 408.7488 418.1047
[2254,] 848.6262 869.2189 888.7148 947.8426
[2255,] 571.9663 609.1649 605.2972 572.0072
[2256,] 1591.2040 1718.3343 1731.3520 1701.3091
[2257,] 1451.1720 1611.0405 1603.0651 1486.8902
[2258,] 761.1301 806.8658 811.5891 801.2333
[2259,] 786.6114 895.6224 874.8427 755.1472
[2260,] 1822.2896 1976.3969 1987.9083 1939.5671
[2261,] 1581.2708 1862.1283 1809.5750 1499.2014
[2262,] 927.9367 1073.4724 1045.2501 885.3618
[2263,] 825.2986 853.7485 868.9937 906.7460
[2264,] 447.9560 510.9141 492.6098 406.2288
[2265,] 1083.3322 1172.7436 1177.9331 1143.7068
[2266,] 765.0612 877.2998 854.0254 727.4747
[2267,] 819.3476 874.4941 878.5533 860.4884
[2268,] 709.0873 538.1039 609.7152 1534.8209
[2269,] 774.1516 839.3359 836.7608 791.4427
[2270,] 1584.7625 1757.1863 1750.9953 1632.9796
[2271,] 1207.5440 1323.9684 1323.7744 1256.8184
[2272,] 559.0869 598.8062 593.4108 554.2441
[2273,] 2231.3943 2319.0255 2370.7705 2498.7562
[2274,] 769.9911 979.5411 911.5337 654.7118
[2275,] 759.0312 728.3931 762.4825 931.3502
[2276,] 886.5847 1037.0656 1004.0324 831.8225
[2277,] 1161.0366 1243.3436 1255.2370 1247.7138
[2278,] 1049.2418 979.5761 1044.6250 1373.9067
[2279,] 1816.2272 1992.4980 1994.6023 1901.1687
[2280,] 870.9105 1057.0856 1006.8481 780.2673
[2281,] 833.2359 955.2730 931.6536 796.6528
[2282,] 726.6204 792.8695 786.8434 730.7969
[2283,] 1060.7232 1147.7500 1152.7805 1119.3251
[2284,] 987.1079 988.8072 1023.8448 1157.4050
[2285,] 1176.5890 1295.3402 1292.8685 1217.1617
[2286,] 1334.0120 1445.7630 1452.5346 1410.9972
[2287,] 1025.3904 1113.8499 1116.1363 1072.3635
[2288,] 1230.5213 1351.6304 1350.3369 1277.4380
[2289,] 1468.2288 1584.9210 1595.8420 1564.8753
[2290,] 837.5080 1000.8677 958.5021 761.7086
[2291,] 1073.5391 1126.1779 1145.9749 1184.2661
[2292,] 1064.4838 1221.3637 1197.0349 1037.3733
[2293,] 734.1592 908.6186 854.5626 642.3557
[2294,] 328.5697 330.1268 334.4984 349.3744
[2295,] 833.4782 924.8154 914.4443 831.4475
[2296,] 990.8975 1071.2061 1074.8184 1040.1987
[2297,] 899.6800 975.4090 975.3434 931.8174
[2298,] 495.6004 506.9510 511.7883 522.0712
[2299,] 1460.0450 1635.1769 1621.2129 1478.4690
[2300,] 509.9020 540.0099 537.3830 511.9120
[2301,] 3020.4673 3275.6350 3275.4575 3130.5810
[2302,] 1120.7647 1324.9841 1283.2739 1050.2531
[2303,] 937.5930 947.3039 975.9876 1079.4758
[2304,] 549.0693 618.3580 599.6895 509.0028
[2305,] 1750.4277 1874.2093 1895.3330 1895.4351
[2306,] 1729.1374 1816.2376 1851.4312 1924.4111
[2307,] 1622.5964 1756.1753 1768.1736 1730.9350
[2308,] 807.3046 954.6061 918.2402 741.8890
[2309,] 725.6744 792.4733 786.1422 728.9706
[2310,] 549.8475 625.2701 603.6720 503.8298
[2311,] 4321.6034 4809.3054 4710.9932 4126.4156
[2312,] 1024.5036 1191.3868 1160.1575 978.2842
[2313,] 780.9068 828.6413 833.7182 822.7708
[2314,] 1055.6716 1208.8487 1185.5675 1030.8764
[2315,] 1073.9716 1196.2083 1187.1800 1089.5072
[2316,] 921.0671 967.6477 980.9569 998.7435
[2317,] 820.5607 862.2151 871.8864 880.9524
[2318,] 678.3169 739.0224 731.8806 676.1021
[2319,] 1057.7002 1212.8169 1188.8251 1031.1534
[2320,] 904.0755 993.8933 988.1861 919.6077
[2321,] 2090.2078 2307.1367 2300.8586 2158.0590
[2322,] 704.9169 1045.8544 904.2609 532.3975
[2323,] 601.0149 562.2472 589.5468 749.3407
[2324,] 623.6022 649.7296 652.9750 648.7336
[2325,] 1100.3228 1157.5788 1176.7986 1210.0853
[2326,] 1395.8355 1454.2945 1485.5732 1562.3278
[2327,] 943.6361 1058.3121 1044.6088 938.5139
[2328,] 901.4420 982.3644 980.2345 927.4127
[2329,] 1504.9591 1758.1212 1712.9905 1441.3368
[2330,] 619.5805 709.8552 684.8431 576.1027
[2331,] 727.2569 813.9698 799.2089 708.5050
[2332,] 579.5541 653.0973 633.5872 540.8624
[2333,] 655.9308 742.2484 722.3942 623.6351
[2334,] 1157.6901 1307.6925 1291.1456 1155.1414
[2335,] 686.7336 884.8481 814.6165 579.8807
[2336,] 514.6237 558.1641 549.9441 500.0949
[2337,] 1194.2716 1658.5649 1500.4822 910.4917
[2338,] 722.8427 786.0346 781.0150 729.6749
[2339,] 747.7204 784.4423 792.3348 798.1197
[2340,] 1084.9613 1290.3235 1245.8267 1009.2176
[2341,] 1097.2839 1115.5147 1150.2275 1267.3091
[2342,] 887.3272 1070.4214 1022.8180 801.9991
[2343,] 1134.4160 1248.4485 1245.8605 1172.5464
[2344,] 2481.4676 2568.6169 2626.5909 2775.5879
[2345,] 1180.1186 1360.0498 1331.7745 1144.9610
[2346,] 701.7450 705.0858 723.1176 790.4759
[2347,] 1172.6814 1422.9889 1363.3932 1060.3568
[2348,] 1027.1721 1150.4153 1138.1609 1030.9082
[2349,] 516.8619 561.9219 553.1069 500.7027
[2350,] 1737.4369 1861.9004 1882.2208 1879.3306
[2351,] 1243.1472 1421.1235 1396.1530 1219.9470
[2352,] 897.2449 926.2759 945.1498 996.3212
[2353,] 837.5808 870.2614 884.2958 915.2339
[2354,] 760.4769 851.8013 837.3342 743.9103
[2355,] 1011.6070 1132.8094 1120.4633 1014.3310
[2356,] 877.9341 872.5563 903.9994 1030.5359
[2357,] 604.9850 642.4530 640.0542 611.0000
[2358,] 524.0223 553.7671 551.6522 528.0036
[2359,] 576.3254 604.0234 604.3030 589.4936
[2360,] 1035.1213 1082.9259 1102.4918 1142.5468
[2361,] 2219.5749 2520.6900 2483.1584 2192.4739
[2362,] 1398.3075 1580.3436 1560.4525 1396.5261
[2363,] 562.5904 623.0707 608.5799 534.1190
[2364,] 696.0842 749.1001 746.5031 708.2706
[2365,] 637.4615 680.7599 678.0719 644.8147
[2366,] 1979.9274 2264.2351 2225.8663 1943.7423
[2367,] 1190.6912 1357.2088 1335.1337 1173.1192
[2368,] 945.0802 883.4733 939.5011 1232.1453
[2369,] 1383.2067 1439.4666 1471.0740 1550.5759
[2370,] 1057.4674 1149.6331 1152.3287 1108.2183
[2371,] 1048.2685 1160.2594 1154.0797 1070.6378
[2372,] 1319.5597 1452.9696 1450.0596 1364.5147
[2373,] 970.8240 1058.3406 1057.8368 1006.2599
[2374,] 1674.2170 1559.1970 1670.7275 2203.9204
[2375,] 677.4730 726.1655 724.0381 689.2878
[2376,] 1065.4961 989.6217 1057.7014 1406.9568
[2377,] 931.1982 973.4091 989.1289 1018.4374
[2378,] 2662.2971 2919.7557 2909.9743 2733.1262
[2379,] 1492.0242 1866.9053 1767.9275 1301.8657
[2380,] 856.7638 993.8142 964.4330 809.0924
[2381,] 935.4856 1161.7118 1097.4848 820.5303
[2382,] 732.5119 809.3204 799.2563 725.9710
[2383,] 1616.7778 1808.9689 1796.1421 1645.8159
[2384,] 1463.2718 1800.0531 1715.7155 1305.6388
[2385,] 848.0743 879.4323 894.7305 930.1426
[2386,] 1499.0787 1755.7753 1708.7738 1430.4137
[2387,] 905.5179 1032.2970 1010.8756 878.5031
[2388,] 1414.1158 1698.7512 1634.8254 1300.7270
[2389,] 851.4339 934.4289 928.6176 863.2564
[2390,] 1259.6129 1362.3917 1369.8126 1335.9183
[2391,] 351.5058 358.5778 361.3535 366.9580
[2392,] 1361.2493 1427.8605 1454.4107 1508.2928
[2393,] 564.3617 576.3372 582.6284 597.9768
[2394,] 5065.8827 5349.1009 5353.8609 5211.1158
[2395,] 1666.9652 1640.1421 1718.3079 2032.6772
[2396,] 810.8296 717.9534 776.5070 1155.3336
[2397,] 596.6383 675.6790 653.7129 557.2400
[2398,] 836.9890 837.1161 864.1584 967.7401
[2399,] 1451.8024 1545.1914 1564.8556 1577.6872
[2400,] 907.9498 1077.0354 1037.0226 838.6837
[2401,] 620.9593 651.7598 652.9898 639.2805
[2402,] 388.4785 547.8256 481.3376 281.5325
[2403,] 995.7313 871.8152 951.9028 1447.7837
[2404,] 728.8590 745.9611 760.3227 801.3237
[2405,] 1083.5640 1161.1244 1171.2300 1160.3813
[2406,] 531.4864 532.8848 542.6553 576.9792
[2407,] 614.4810 614.5112 628.0516 680.1528
[2408,] 810.2729 853.3155 861.9695 866.6234
[2409,] 477.7370 495.6866 497.4137 493.0661
[2410,] 746.6125 814.7668 809.4203 754.1603
[2411,] 864.6410 900.7648 915.1220 943.8458
[2412,] 1098.2573 1184.1000 1191.4867 1166.6808
[2413,] 614.4355 674.1429 662.6334 598.5485
[2414,] 521.2486 537.4247 540.8997 543.5662
[2415,] 684.5262 707.1005 716.3075 734.6633
[2416,] 809.8421 819.4573 841.6089 917.9416
[2417,] 645.1235 661.0579 670.3129 693.0882
[2418,] 862.9837 764.8395 828.8390 1226.8399
[2419,] 838.2707 1032.0595 975.6365 737.1126
[2420,] 979.7727 1067.6660 1067.4566 1016.5848
[2421,] 828.6836 855.6708 871.6463 913.1815
[2422,] 723.4809 751.3102 761.0378 777.4506
[2423,] 1321.1259 1541.9837 1501.6895 1259.6945
[2424,] 459.8016 513.9973 499.8689 428.0773
[2425,] 1281.6876 1460.8586 1437.0151 1262.7087
[2426,] 639.6391 713.4814 697.1844 614.8630
[2427,] 809.9498 883.6326 879.5203 824.5648
[2428,] 641.4482 698.0301 689.9798 634.5699
[2429,] 698.6846 778.5825 764.6074 681.9164
[2430,] 774.9952 783.2468 803.7406 875.9818
[2431,] 796.7601 1030.2136 952.1343 666.5538
[2432,] 3891.6006 4505.0126 4357.6856 3496.1977
[2433,] 512.3679 548.8376 543.5811 506.4185
[2434,] 721.8051 808.3534 793.2781 701.8757
[2435,] 780.8441 868.1388 856.5694 772.5718
[2436,] 908.4275 1020.5471 1005.6316 898.4191
[2437,] 1160.9011 1472.9204 1384.9818 990.6788
[2438,] 828.7771 785.9352 828.6974 1043.3852
[2439,] 717.8408 776.1678 772.8236 729.2157
[2440,] 1028.7973 1125.7748 1124.7105 1065.3893
[2441,] 728.4791 811.5961 798.5166 713.8961
[2442,] 1076.7260 1177.8271 1177.8266 1120.0295
[2443,] 1842.7960 2279.4528 2171.1204 1620.6692
[2444,] 429.0718 422.3216 432.8951 476.5010
[2445,] 700.1792 789.5808 771.6061 674.1349
[2446,] 710.4132 830.0006 799.2193 657.9212
[2447,] 1041.8089 1113.9423 1123.9778 1115.7487
[2448,] 915.4288 969.7594 979.5451 980.2127
[2449,] 578.9673 602.1362 604.3958 598.8241
[2450,] 1009.5524 1094.9967 1097.5853 1056.5061
[2451,] 1300.3086 1466.2260 1448.6997 1300.4349
[2452,] 577.1378 608.2678 607.1399 585.7983
[2453,] 630.3819 679.4437 673.7582 629.2187
[2454,] 823.3530 800.9984 836.0332 993.2681
[2455,] 1221.9237 1317.8270 1326.6972 1302.2395
[2456,] 887.2416 976.4052 969.9093 899.7181
[2457,] 920.7840 1145.7568 1080.8352 804.8410
[2458,] 1214.1747 1372.9636 1355.1082 1209.7398
[2459,] 854.8222 1034.7249 985.9871 767.1029
[2460,] 730.8021 730.5744 751.2600 834.4983
[2461,] 1013.5569 988.2351 1034.9543 1240.1461
[2462,] 1042.8516 1155.3663 1148.6306 1063.1616
[2463,] 912.0476 990.2725 989.9423 943.9380
[2464,] 1552.3068 1893.5251 1812.8763 1402.7338
[2465,] 1419.5654 1545.5434 1550.2541 1493.5020
[2466,] 820.5171 908.3227 898.7233 820.1027
[2467,] 682.3741 723.1173 724.6735 705.9433
[2468,] 519.0945 552.9104 548.9518 517.2330
[2469,] 830.4988 890.7615 893.3088 866.8937
[2470,] 842.4014 779.3248 830.0622 1107.8332
[2471,] 1662.0567 1797.3254 1810.1508 1776.3719
[2472,] 828.9630 889.6631 891.9437 864.4471
[2473,] 1116.6123 803.0233 945.6060 2250.3068
[2474,] 496.0324 515.9982 517.2813 510.2941
[2475,] 770.8214 755.8493 785.3384 912.3531
[2476,] 657.1472 710.1790 704.7454 658.8850
[2477,] 684.8320 759.8030 746.5498 669.0008
[2478,] 651.8383 666.7280 676.9356 704.8885
[2479,] 339.2531 349.5905 350.6791 348.4822
[2480,] 674.0979 687.5309 699.2410 735.1862
[2481,] 1092.2636 1291.9592 1250.3526 1023.2601
[2482,] 675.2882 667.9502 687.8353 774.9812
[2483,] 1143.0565 1348.0671 1307.3997 1074.3016
[2484,] 1684.6490 1855.4048 1854.4028 1754.2144
[2485,] 694.3355 871.3079 812.2047 600.5327
[2486,] 672.0988 860.8294 793.4612 569.8859
[2487,] 677.5623 714.8159 717.4733 704.1745
[2488,] 511.6636 530.1149 532.4074 529.6878
[2489,] 798.8735 808.1650 829.7646 904.1581
[2490,] 414.3378 439.7974 436.7517 412.7307
[2491,] 658.3679 705.0830 702.4037 667.9369
[2492,] 940.7759 1001.8216 1010.4407 1003.6893
[2493,] 1461.5495 1546.5509 1570.1261 1601.8688
[2494,] 1142.9901 1313.6451 1287.5675 1113.2010
[2495,] 1497.5005 1891.4791 1784.2710 1290.1906
[2496,] 580.6019 612.0236 610.8973 589.4380
[2497,] 911.7646 1009.6547 1001.0225 919.2565
[2498,] 847.7829 877.1893 893.2236 932.8228
[2499,] 920.6809 992.2556 995.2449 963.2114
[2500,] 1320.3335 1441.8994 1443.9775 1381.2137
[2501,] 692.4413 717.5183 726.2754 741.9182
[2502,] 1939.9090 1804.8644 1935.6548 2533.4519
[2503,] 538.9107 573.7860 569.8880 537.7444
[2504,] 1315.4968 1355.9020 1390.9059 1492.6370
[2505,] 1050.4349 1238.9942 1199.9368 986.4539
[2506,] 1638.3138 1816.1212 1810.2537 1689.9371
[2507,] 595.7893 604.4285 613.1308 640.5775
[2508,] 988.1736 997.7946 1029.7646 1145.0012
[2509,] 608.0258 635.9460 637.7202 627.5478
[2510,] 976.4878 1126.6443 1099.6571 939.8327
[2511,] 559.0996 616.6461 603.5381 533.0815
[2512,] 1583.1559 1951.0437 1859.8294 1411.5848
[2513,] 1886.5407 2070.1665 2071.2698 1971.9623
[2514,] 634.1305 673.6595 672.2914 645.1297
[2515,] 581.6640 586.7565 596.5330 629.3748
[2516,] 443.9490 508.1996 489.1976 400.7435
[2517,] 1329.0525 1647.1732 1563.8705 1167.8053
[2518,] 1730.0591 1930.0283 1918.6195 1769.4429
[2519,] 862.9217 925.7757 929.0525 903.5642
[2520,] 849.6900 922.3855 920.8106 874.0901
[2521,] 906.9241 940.5525 957.9864 1001.1093
[2522,] 807.7548 782.5792 817.6372 979.5812
[2523,] 984.1314 1061.4898 1065.8842 1035.8397
[2524,] 612.1767 697.2372 674.3908 571.2562
[2525,] 1047.4695 1177.1903 1163.4434 1048.0121
[2526,] 581.4496 592.3162 599.7329 619.7748
[2527,] 560.4687 596.1312 592.5029 560.9273
[2528,] 1121.9352 1219.2786 1223.0477 1179.6115
[2529,] 3665.8959 3822.1316 3866.4508 3938.1829
[2530,] 1123.9058 1319.0041 1281.3733 1063.4696
[2531,] 944.2453 1073.5788 1053.4851 922.8058
[2532,] 1588.1397 1809.7061 1783.1608 1575.5721
[2533,] 907.5228 1081.8636 1039.4111 833.2919
[2534,] 659.8471 721.3220 712.4935 652.4221
[2535,] 650.8990 709.5743 701.2239 645.0598
[2536,] 752.5289 713.7832 749.9951 942.3874
[2537,] 437.6017 387.0384 414.2353 572.6163
[2538,] 369.1093 375.9270 379.3235 387.1419
[2539,] 1049.5660 1092.7367 1115.0332 1168.2359
[2540,] 615.1327 644.6680 646.1804 634.4791
[2541,] 816.5732 975.2935 934.2819 742.0917
[2542,] 736.9302 882.7983 842.4399 666.2036
[2543,] 963.9135 1385.0377 1231.6137 722.1850
[2544,] 607.7087 608.8516 621.3229 668.9601
[2545,] 886.8028 1014.6758 991.5554 855.3374
[2546,] 816.1996 935.9556 912.3381 779.5309
[2547,] 592.5138 613.9869 617.5039 616.5955
[2548,] 541.2374 574.0959 571.1098 542.9415
[2549,] 1759.6904 1774.3212 1839.5887 2071.6554
[2550,] 687.9637 947.5792 846.8141 549.9858
[2551,] 582.8985 655.1462 636.3235 546.3403
[2552,] 1079.5775 1126.6528 1148.9914 1200.0166
[2553,] 1952.4225 2404.7395 2291.8712 1721.1028
[2554,] 759.9628 844.1096 832.6930 751.2633
[2555,] 936.2831 1022.6034 1020.4294 963.7165
[2556,] 730.3362 686.8693 723.5699 925.9486
[2557,] 995.6154 1105.8244 1097.1717 1008.0519
[2558,] 2055.0186 2178.6929 2210.3847 2247.9596
[2559,] 739.4805 786.2566 789.3734 772.6007
[2560,] 657.4801 703.5788 701.0954 667.5821
[2561,] 662.0751 739.8895 724.1965 638.5221
[2562,] 1121.3852 1215.8272 1220.7747 1182.8744
[2563,] 718.2619 805.5188 789.8630 696.7419
[2564,] 718.4755 724.1219 741.8134 807.6608
[2565,] 1393.2879 1805.4048 1682.5794 1156.4542
[2566,] 1181.4808 1402.1890 1356.1290 1100.8774
[2567,] 781.4751 876.2867 861.5294 764.6034
[2568,] 695.6771 649.1661 684.6575 893.7635
[2569,] 754.0766 730.7682 761.9722 910.0000
[2570,] 808.7804 826.3123 845.2401 903.5374
[2571,] 755.5902 876.1472 848.6633 708.9999
[2572,] 574.0414 647.6443 627.7679 534.1637
[2573,] 1302.8183 1459.0938 1445.7730 1315.2879
[2574,] 757.9565 822.8388 819.4858 772.2528
[2575,] 1381.6584 1565.6652 1544.1570 1374.4574
[2576,] 505.6145 512.3086 519.2862 540.0497
[2577,] 1403.4928 1468.6315 1497.5563 1561.3004
[2578,] 904.6069 1026.0683 1006.8862 883.1813
[2579,] 801.7346 845.2472 853.2279 855.0958
[2580,] 864.3734 1022.2934 984.1961 798.0828
[2581,] 601.6214 653.5863 644.7586 589.8214
[2582,] 792.6101 865.0323 860.4552 804.7107
[2583,] 838.6317 889.9343 896.6414 888.9788
[2584,] 848.3202 877.9337 893.9261 933.1590
[2585,] 479.5593 488.2751 493.8557 508.2964
[2586,] 1487.4213 1729.6241 1688.3036 1432.5511
[2587,] 673.4033 732.3691 725.6028 672.0391
[2588,] 1464.1481 1597.6706 1601.4086 1536.9901
[2589,] 871.1337 963.3205 954.7456 875.8247
[2590,] 890.8693 856.0893 899.2209 1105.3151
[2591,] 3145.9631 3409.6087 3407.6047 3254.1349
[2592,] 1382.7921 1505.0412 1509.6429 1454.9384
[2593,] 647.8559 640.0164 658.2580 740.2851
[2594,] 1854.5606 2070.1397 2056.8754 1891.9099
[2595,] 1022.2002 1234.2946 1182.9373 930.9804
[2596,] 514.3221 571.5540 557.4035 483.5316
[2597,] 826.1474 972.4379 937.6089 764.1826
[2598,] 604.0468 630.7468 632.7962 624.0910
[2599,] 910.6086 1002.5168 996.3431 925.0883
[2600,] 660.8872 708.0728 705.3761 670.4926
[2601,] 479.3622 473.4996 484.9811 530.5162
[2602,] 631.0611 695.7853 683.4586 612.7254
[2603,] 448.2910 451.5060 458.6044 481.9721
[2604,] 765.6933 803.9550 811.9386 817.3341
[2605,] 739.5679 797.2873 795.8449 757.9788
[2606,] 834.4064 894.9031 897.5690 871.3436
[2607,] 544.1335 580.5700 576.1465 541.4970
[2608,] 758.5645 896.6939 861.3978 696.1112
[2609,] 839.3989 864.2231 881.5107 929.7381
[2610,] 672.0795 711.8970 713.0914 693.4947
[2611,] 845.1165 852.5006 877.0019 965.3126
[2612,] 576.9266 606.4779 606.0039 587.6778
[2613,] 1895.9921 1790.1878 1907.9643 2435.3418
[2614,] 887.9080 1163.2855 1071.9484 732.5508
[2615,] 961.0294 1023.0987 1032.5896 1028.6874
[2616,] 459.4079 426.8843 448.2443 555.9719
[2617,] 704.2394 739.9710 744.9289 741.2381
[2618,] 776.6535 1032.9140 942.2141 634.4289
[2619,] 2443.1552 2639.3476 2650.9850 2576.7509
[2620,] 460.0090 453.4365 464.7645 510.3133
[2621,] 454.9376 420.8753 442.6807 554.3251
[2622,] 885.6252 925.2131 939.3118 965.3035
[2623,] 605.2082 641.0200 639.3305 613.3204
[2624,] 724.8833 753.7629 763.1642 777.8500
[2625,] 890.1773 1048.1464 1012.0439 828.5887
[2626,] 620.8627 632.7020 641.6660 667.9330
[2627,] 502.9942 493.8318 507.1579 562.1092
[2628,] 588.8500 613.9902 615.7776 607.2682
[2629,] 1138.4395 1318.9954 1288.4773 1096.4511
[2630,] 1068.2430 1283.5115 1233.7243 980.4912
[2631,] 1144.5311 1295.1082 1277.5415 1138.9872
[2632,] 897.8134 1011.0491 994.9673 884.2071
[2633,] 1262.7520 1561.7651 1484.3175 1111.7245
[2634,] 594.0394 587.9811 602.5725 664.3795
[2635,] 680.2518 790.3018 760.9960 631.6173
[2636,] 422.0658 408.0838 421.3156 480.9895
[2637,] 349.3372 370.8166 367.5170 345.1079
[2638,] 599.9343 689.8377 663.4313 551.6283
[2639,] 725.0092 793.2508 786.2571 726.4566
[2640,] 570.0927 673.1451 638.6773 503.5086
[2641,] 560.1459 583.6809 585.1267 576.4972
[2642,] 821.4307 852.2543 866.3790 898.3271
[2643,] 555.5165 635.1800 611.5511 506.3494
[2644,] 1336.5701 1410.3173 1432.9313 1467.8354
[2645,] 573.1604 644.9195 625.7921 534.9868
[2646,] 1633.6013 1979.7048 1900.6853 1490.1337
[2647,] 751.4113 792.8116 798.9460 795.9238
[2648,] 1200.9745 1232.3710 1266.8102 1371.3910
[2649,] 504.3965 512.5713 518.9146 536.4788
[2650,] 475.5984 496.1281 496.7294 487.1280
[2651,] 1037.1422 1154.2560 1145.2220 1050.5095
[2652,] 871.5747 868.8650 898.8513 1017.4065
[2653,] 781.5166 802.5484 818.3787 863.1290
[2654,] 843.7045 1029.0397 976.9220 749.5691
[2655,] 742.6427 746.3795 767.1282 842.8337
[2656,] 645.4142 599.7022 631.3418 832.4130
[2657,] 528.5175 511.8629 528.7596 603.7541
[2658,] 415.7344 439.8646 437.4208 415.9970
[2659,] 502.2034 452.3277 481.3846 640.8229
[2660,] 656.3729 655.3086 672.1049 737.8273
[2661,] 752.6481 760.5066 780.2986 849.2423
[2662,] 614.9123 653.8884 651.3461 621.7248
[2663,] 527.7707 496.2569 518.9234 631.5294
[2664,] 494.6746 518.9321 518.3938 502.9378
[2665,] 664.3803 702.7146 703.9744 685.7415
[2666,] 928.0412 1097.9263 1058.6349 861.6993
[2667,] 817.8173 893.8460 889.0867 831.2747
[2668,] 895.5809 992.8914 983.4703 900.1020
[2669,] 750.3179 786.8861 794.9662 801.5287
[2670,] 1015.9797 1007.2396 1047.6680 1212.3092
[2671,] 697.8264 740.2181 742.1880 724.5864
[2672,] 594.3341 647.5492 637.8306 579.6197
[2673,] 806.8864 818.8544 839.9044 910.1204
[2674,] 988.0101 1202.0947 1147.5457 890.5993
[2675,] 517.0194 535.3331 537.8170 535.8342
[2676,] 1399.6899 1496.3590 1512.2832 1510.4354
[2677,] 613.1689 690.2050 671.0236 579.8481
[2678,] 750.5629 755.4547 776.3490 851.6687
[2679,] 1227.9939 924.1207 1073.7327 2242.0234
[2680,] 1826.1886 2147.0283 2087.5848 1729.9508
[2681,] 815.7029 860.1384 868.4686 871.2048
[2682,] 634.3835 687.7402 680.5492 629.2976
[2683,] 472.2291 497.8704 496.2513 476.5092
[2684,] 964.8132 1160.9886 1112.8922 880.8478
[2685,] 981.4424 885.9793 955.7723 1357.0992
[2686,] 472.0285 531.1303 515.1170 435.6407
[2687,] 671.1350 688.8850 698.7023 724.3882
[2688,] 1412.9894 1731.8638 1652.5342 1264.5782
[2689,] 1304.2953 1549.6960 1497.8019 1212.5061
[2690,] 515.7552 525.8521 531.6921 546.2620
[2691,] 1223.1749 1368.9560 1356.9849 1236.5161
[2692,] 841.1488 881.7558 892.9510 907.5547
[2693,] 457.0831 462.4684 468.8982 488.4610
[2694,] 805.9729 650.6007 725.8379 1397.6766
[2695,] 507.7167 515.6482 522.1711 540.5337
[2696,] 1035.3984 1269.4267 1209.0700 925.9150
[2697,] 695.7540 718.7720 728.6119 749.6363
[2698,] 1539.4984 1678.9115 1684.1273 1621.0748
[2699,] 1099.6046 1175.3092 1186.9392 1182.5023
[2700,] 567.0191 591.2092 592.6228 583.4683
[2701,] 1427.2704 1561.3624 1563.0427 1491.7794
[2702,] 375.5800 375.2490 381.7524 405.6166
[2703,] 575.2908 620.2302 612.9962 566.5322
[2704,] 905.7715 1033.5871 1011.7334 877.6899
[2705,] 1033.1121 1181.7846 1159.0045 1008.6614
[2706,] 540.4286 520.0941 538.7346 624.5095
[2707,] 713.4452 770.9957 767.6496 724.6470
[2708,] 868.9109 959.0151 951.1954 875.6695
[2709,] 501.6775 519.8371 522.0009 519.0197
[2710,] 518.9689 554.4640 549.7897 514.9381
[2711,] 446.0163 650.7777 562.3246 307.6176
[2712,] 774.5998 937.1439 891.4158 692.9878
[2713,] 723.4559 767.4612 770.5248 754.4336
[2714,] 544.3772 625.1056 600.9487 492.2657
[2715,] 5491.9845 6071.3895 5957.2721 5184.1417
[2716,] 645.0828 684.0747 683.8015 660.3732
[2717,] 895.0632 1069.6170 1026.3888 818.4430
[2718,] 801.5680 833.7768 846.3722 871.3352
[2719,] 931.9553 1046.2809 1031.9574 924.6141
[2720,] 670.0209 688.3742 697.8417 722.0179
[2721,] 378.7782 404.1129 400.0577 373.2023
[2722,] 766.7664 861.1210 845.7099 747.6369
[2723,] 646.8763 691.0357 688.7395 656.0026
[2724,] 956.3767 1044.9735 1043.1470 986.5402
[2725,] 484.6426 506.3522 506.6605 495.4440
[2726,] 859.3435 977.0058 956.5981 832.4368
[2727,] 742.1115 783.4516 789.0180 783.7872
[2728,] 641.3263 679.7695 679.4263 655.8557
[2729,] 530.4548 566.3564 561.8057 527.0877
[2730,] 696.4328 684.2383 707.5719 813.9750
[2731,] 637.7436 593.4710 624.0887 817.2992
[2732,] 760.1143 895.0775 861.3116 700.5980
[2733,] 558.1246 570.3074 576.3512 590.5675
[2734,] 873.5385 938.0098 941.2137 914.7259
[2735,] 1180.9880 1324.9641 1312.1505 1189.7046
[2736,] 831.5549 877.4301 885.8684 888.0269
[2737,] 562.2592 608.3873 600.3749 549.9426
[2738,] 626.8180 689.3051 677.5995 610.0894
[2739,] 586.1333 627.3523 622.2683 583.8673
[2740,] 1545.3106 1639.1694 1663.4335 1692.1305
[2741,] 698.6867 719.9804 730.6657 756.3590
[2742,] 699.0966 761.9103 755.2730 700.5168
[2743,] 706.1181 734.6704 742.6495 754.1172
[2744,] 591.0337 698.3998 663.0242 526.0358
[2745,] 900.8830 832.1978 888.0302 1194.5995
[2746,] 653.9666 702.5570 698.7731 660.2288
[2747,] 1052.5194 1238.1962 1200.5431 991.9269
[2748,] 409.5333 406.4295 415.0263 448.5909
[2749,] 3479.0865 3900.4386 3836.6115 3370.8075
[2750,] 710.6981 770.7686 766.1547 718.2014
[2751,] 493.3725 505.5346 509.9901 518.4531
[2752,] 462.9445 530.1910 510.3672 417.4279
[2753,] 1054.7923 1190.8805 1174.8905 1049.4302
[2754,] 763.2157 716.6822 756.3759 972.4769
[2755,] 563.3373 605.5636 599.2544 555.9336
[2756,] 636.9052 672.2917 672.8757 653.8060
[2757,] 602.8763 743.0633 692.0535 517.7344
[2758,] 576.7704 606.5565 605.9787 587.1790
[2759,] 696.6656 809.9819 781.2268 648.0740
[2760,] 559.5392 614.9134 602.8256 535.9448
[2761,] 506.2925 449.7766 481.3953 662.9072
[2762,] 444.6133 447.1640 454.4216 478.8958
[2763,] 532.8387 623.9003 594.7061 469.1924
[2764,] 535.1565 585.5351 574.8783 514.4336
[2765,] 584.3287 567.6299 586.0068 673.2946
[2766,] 415.6013 442.0057 438.5964 412.9257
[2767,] 795.1515 815.8534 832.7534 880.5738
[2768,] 652.0569 710.4795 702.3825 646.8769
[2769,] 815.8041 745.4345 797.4129 1093.9534
[2770,] 471.4463 498.0279 495.9951 474.4038
[2771,] 549.1378 583.1125 579.8494 550.2410
[2772,] 1148.6481 1345.3066 1308.5242 1089.8683
[2773,] 761.3709 663.3618 719.4768 1126.2916
[2774,] 503.1967 530.4653 528.8636 508.2562
[2775,] 1151.7631 1259.7432 1260.5452 1201.3764
[2776,] 642.9000 726.4978 706.3577 610.1777
[2777,] 1042.6858 1212.9531 1181.4268 996.4460
[2778,] 436.8120 471.5511 465.1904 425.9996
[2779,] 553.3724 573.7838 576.3145 573.2924
[2780,] 668.6984 714.2663 712.8121 682.1649
[2781,] 901.1555 946.9334 959.1786 975.1088
[2782,] 812.4573 906.2360 893.6330 803.6173
[2783,] 852.1309 883.2865 898.9547 935.4349
[2784,] 406.5568 427.3289 426.0428 410.1003
[2785,] 454.4499 473.5781 474.2765 465.7970
[2786,] 791.8446 832.5020 841.1029 846.6241
[2787,] 653.4772 744.8082 722.5714 616.2785
[2788,] 1000.7379 1186.4288 1145.3864 931.7386
[2789,] 660.2742 683.0615 690.3243 702.7770
[2790,] 390.8633 403.7927 405.3182 403.1595
[2791,] 1654.5284 1822.1229 1821.2063 1722.7371
[2792,] 714.4526 833.7852 803.3686 662.7787
[2793,] 593.3547 640.4375 633.2827 585.5072
[2794,] 688.5081 698.9822 713.3850 759.3616
[2795,] 570.1759 639.3119 621.1271 534.1214
[2796,] 874.7439 962.7845 956.1751 885.2890
[2797,] 1347.6367 1409.5896 1437.5289 1498.7130
[2798,] 651.2333 646.7215 664.3340 738.2847
[2799,] 483.1861 539.8617 525.1678 450.2789
[2800,] 601.6016 753.0972 696.0197 508.8435
[2801,] 455.9544 464.3504 469.5224 482.7375
[2802,] 536.5406 535.1915 546.1949 587.0195
[2803,] 477.6960 488.7613 493.3330 502.8153
[2804,] 953.9453 970.5740 997.9932 1088.8214
[2805,] 1321.3004 1496.4585 1475.9373 1313.9226
[2806,] 981.9512 1462.6492 1282.2437 708.1371
[2807,] 552.3860 600.9362 591.5308 535.9307
[2808,] 1123.3501 1387.7036 1319.7247 993.4534
[2809,] 559.1204 788.5533 684.8334 414.7561
[2810,] 1216.9809 1105.4825 1194.8982 1656.7277
[2811,] 963.9982 998.8000 1019.5799 1073.0373
[2812,] 699.1396 759.0561 753.6497 703.9763
[2813,] 841.6865 940.5109 927.4103 832.4390
[2814,] 407.7487 440.0620 433.8982 397.0074
[2815,] 549.0044 565.9259 569.7906 573.3746
[2816,] 1637.4815 1652.6923 1713.0787 1927.1745
[2817,] 705.0480 783.9446 770.8814 690.1638
[2818,] 641.8269 716.9592 700.3774 616.5022
[2819,] 548.9551 570.0245 572.1701 567.4579
[2820,] 950.0721 1026.1285 1029.1303 995.0571
[2821,] 1054.2284 1162.2779 1158.1274 1083.2200
[2822,] 409.8223 483.1971 458.9279 357.0693
[2823,] 526.7499 585.0557 570.7443 495.9875
[2824,] 521.3357 594.9735 573.6498 473.4097
[2825,] 713.8550 729.1522 742.8002 785.3382
[2826,] 1078.5948 1193.6692 1187.8944 1104.1081
[2827,] 845.8836 907.3009 910.2211 884.1159
[2828,] 631.8813 678.0544 673.7108 634.4418
[2829,] 1229.2332 1367.7490 1359.0846 1252.9170
[2830,] 542.5355 521.8189 540.6622 627.8162
[2831,] 824.3051 928.8571 912.2997 805.2387
[2832,] 962.7359 954.3794 991.8721 1145.1334
[2833,] 456.9196 481.8883 480.1971 460.5950
[2834,] 575.8780 610.1821 607.6756 580.1582
[2835,] 495.1225 531.9867 526.1295 486.9268
[2836,] 729.3183 799.5084 792.0170 729.5736
[2837,] 897.3592 1060.1596 1022.4000 832.1915
[2838,] 450.1655 467.5631 468.8778 463.4455
[2839,] 461.7648 452.9675 465.2248 515.8670
[2840,] 1057.0360 1196.9771 1179.4768 1047.6660
[2841,] 719.8629 807.0974 791.5753 698.7339
[2842,] 449.3137 496.9159 485.3581 424.3926
[2843,] 598.1152 659.3682 646.0134 575.9156
[2844,] 484.8408 481.4979 492.0986 532.5442
[2845,] 432.2386 423.8938 435.1889 482.6299
[2846,] 526.0184 633.7876 596.3541 446.8341
[2847,] 563.5273 621.6701 608.2800 537.7281
[2848,] 457.7018 508.5097 495.7979 429.6538
[2849,] 845.5473 733.8834 800.8547 1249.7300
[2850,] 909.9244 835.5798 893.9344 1219.5050
[2851,] 603.1317 597.3298 612.0520 676.0752
[2852,] 278.6035 286.4830 286.5556 282.1678
[2853,] 940.5484 943.1622 974.7280 1095.9958
[2854,] 695.6356 655.5411 688.7993 876.5616
[2855,] 821.1092 859.6982 870.6466 886.1057
[2856,] 509.5563 552.0176 544.1319 495.8304
[2857,] 592.5306 616.0627 618.7637 613.7162
[2858,] 532.2062 558.8132 558.2233 541.2548
[2859,] 743.1760 838.3947 821.0514 719.8673
[2860,] 610.9042 628.0140 634.4239 646.6365
[2861,] 620.3737 662.2617 658.8247 625.0906
[2862,] 704.2065 729.8389 738.9467 756.3344
[2863,] 537.1504 584.6442 575.2925 520.0613
[2864,] 702.3643 866.7989 814.4554 616.4135
[2865,] 483.9803 480.9240 491.3889 531.1380
[2866,] 453.9203 540.2552 511.6027 389.7915
[2867,] 1023.7797 1165.9762 1145.3927 1004.6903
[2868,] 593.9627 656.6102 642.5566 569.3079
[2869,] 766.5331 683.7981 735.5782 1077.6405
[2870,] 1162.7541 1218.0583 1241.0430 1289.2222
[2871,] 508.0665 568.7181 552.9008 472.8146
[2872,] 529.8563 604.5477 582.8926 481.7460
[2873,] 444.2421 464.4954 464.4614 452.8874
[2874,] 508.5598 535.1168 533.9493 515.1358
[2875,] 968.9183 1030.0922 1040.4202 1040.0671
[2876,] 586.4805 585.5991 597.9195 645.1633
[2877,] 653.6221 766.5147 733.9453 599.5462
[2878,] 1317.1968 1561.7502 1510.8576 1228.6924
[2879,] 736.4742 740.2910 760.2562 834.5359
[2880,] 933.7539 1247.1633 1142.0187 754.7810
[2881,] 796.7347 845.7605 851.1877 840.9771
[2882,] 665.1424 755.3606 734.1928 630.6026
[2883,] 748.9632 825.2117 816.5460 747.5435
[2884,] 463.9783 496.7035 491.8972 458.2300
[2885,] 803.9876 919.7222 897.0206 769.1905
[2886,] 1362.9534 1508.4377 1502.4210 1400.4940
[2887,] 617.9828 669.4316 661.7538 611.3129
[2888,] 599.4114 673.9524 654.2832 564.8588
[2889,] 781.5084 854.6103 849.1137 790.4537
[2890,] 608.8182 641.9775 641.6126 621.4153
[2891,] 952.1941 1050.0422 1044.0502 969.2167
[2892,] 668.5323 724.8303 718.8384 669.1242
[2893,] 566.8169 674.2106 637.4712 495.9518
[2894,] 705.8880 694.0670 718.1022 824.1575
[2895,] 701.8405 741.3780 744.6757 733.1484
[2896,] 528.2682 490.5509 515.6233 645.2447
[2897,] 615.6181 651.0541 650.1156 627.0022
[2898,] 519.2671 612.4067 582.0632 451.7874
[2899,] 547.0773 567.3949 569.8048 566.4210
[2900,] 847.5178 917.3479 916.8510 875.1255
[2901,] 514.4876 553.6154 547.2812 505.4017
[2902,] 852.3785 896.6828 907.0247 916.2904
[2903,] 424.1684 433.7080 437.5857 445.5192
[2904,] 655.4818 778.5932 741.0541 594.0847
[2905,] 476.1480 458.1960 474.4148 547.1963
[2906,] 733.3313 806.2531 797.9092 731.4301
[2907,] 1322.3270 1528.3439 1494.5699 1278.2649
[2908,] 1622.3137 2009.2198 1912.1527 1436.0220
[2909,] 771.2679 813.1727 820.1227 818.7939
[2910,] 765.5778 820.1368 821.5307 794.7024
[2911,] 627.0694 677.7720 671.1272 623.2073
[2912,] 957.7585 1047.4021 1045.2268 986.9581
[2913,] 883.1222 1053.5083 1011.3872 808.5550
[2914,] 544.2586 628.5992 602.6979 488.6966
[2915,] 501.0382 539.1980 532.9306 491.7822
[2916,] 624.5735 741.8858 704.3327 560.7066
[2917,] 866.9495 1049.8654 1000.7707 778.5185
[2918,] 471.1973 563.1618 532.3592 402.1439
[2919,] 553.4177 589.7575 585.5937 552.0816
[2920,] 739.7756 709.5645 742.0689 906.8119
[2921,] 3537.5499 3836.7901 3822.6272 3601.7130
[2922,] 567.0039 583.9247 588.3501 593.6905
[2923,] 577.4176 624.5596 616.3994 566.5886
[2924,] 782.1529 764.2950 795.3421 932.2302
[2925,] 672.0285 700.8480 706.5965 708.4476
[2926,] 585.6725 640.1091 629.3533 568.2096
[2927,] 723.0998 703.7323 731.4585 861.4326
[2928,] 371.9671 381.9100 384.1018 385.9101
[2929,] 601.7090 664.2386 650.2750 579.2164
[2930,] 693.6764 790.2928 768.5354 659.2534
[2931,] 6143.5705 6510.6969 6458.9868 6070.8351
[2932,] 482.2727 555.4785 533.4494 431.5777
[2933,] 640.8657 678.4123 678.4074 656.4191
[2934,] 457.7612 515.5371 499.7912 422.0097
[2935,] 945.8409 818.7630 897.1777 1404.1166
[2936,] 879.1131 1216.4255 1094.3548 687.2722
[2937,] 586.0686 584.7966 597.2638 645.3318
[2938,] 731.6270 762.2426 771.4320 784.6421
[2939,] 1601.3591 2017.6780 1906.4434 1384.5901
[2940,] 447.8644 469.3124 468.8753 455.3144
[2941,] 627.7943 690.7667 678.9308 610.7246
[2942,] 943.4435 1090.4101 1062.3639 903.0265
[2943,] 415.0533 434.3884 433.9410 421.5511
[2944,] 643.8570 686.3690 684.5223 653.9635
[2945,] 1254.7367 1378.0899 1376.7627 1302.7677
[2946,] 435.3969 423.5894 436.3309 491.9660
[2947,] 414.2440 439.6832 436.6434 412.6526
[2948,] 565.6269 578.6341 584.5752 597.8694
[2949,] 1939.3819 3118.6512 2678.9729 1140.3330
[2950,] 564.0319 638.6707 617.6344 521.2827
[2951,] 855.1650 1031.1161 984.1906 770.9727
[2952,] 264.3691 281.0162 276.7777 255.5402
[2953,] 639.2162 699.5629 689.6531 627.7206
[2954,] 487.3564 479.5005 491.9687 542.5929
[2955,] 624.0446 657.7905 658.0556 639.4745
[2956,] 492.8957 511.5162 513.2906 508.7405
[2957,] 494.2104 472.3094 490.4853 574.1778
[2958,] 641.8937 736.3198 711.2817 599.6206
[2959,] 623.9033 703.1552 683.6514 590.7037
[2960,] 640.5314 654.0826 663.9510 690.1166
[2961,] 746.4056 806.1298 804.3719 764.6815
[2962,] 630.6032 668.9881 667.8224 642.0764
[2963,] 443.9123 487.1485 477.3387 423.5827
[2964,] 403.9503 474.3862 451.1842 353.6174
[2965,] 818.8633 855.9209 867.4028 885.6703
[2966,] 618.2785 646.9263 648.8968 639.2375
[2967,] 842.3815 836.2157 865.9516 986.1525
[2968,] 1141.0983 1100.5987 1160.1398 1422.5821
[2969,] 482.5445 514.1683 510.2611 479.9023
[2970,] 516.1166 562.1102 552.8741 498.7538
[2971,] 799.3746 847.1504 853.2423 846.0702
[2972,] 846.0159 859.1306 881.3875 956.8401
[2973,] 693.1376 751.6976 746.4268 697.3492
[2974,] 706.0265 704.2702 724.4800 804.9600
[2975,] 662.5759 779.6718 745.3442 606.1065
[2976,] 789.4778 803.2145 822.4241 884.6940
[2977,] 563.0757 567.3095 576.7202 608.3986
[2978,] 771.4156 764.2690 790.7203 898.5399
[2979,] 676.7463 838.5293 784.7971 590.9385
[2980,] 476.7288 490.6576 494.0260 497.6334
[2981,] 685.4715 767.5568 751.1546 662.6746
[2982,] 477.7952 508.3113 504.7682 476.1549
[2983,] 576.5697 588.7490 595.4575 611.7860
[2984,] 4782.6910 5045.2092 5053.1280 4931.7319
[2985,] 521.8156 608.1226 580.9926 461.1565
[2986,] 383.8101 390.0942 394.1499 404.6472
[2987,] 543.6228 640.5154 608.5039 476.4535
[2988,] 352.5816 377.5350 372.8324 344.4346
[2989,] 744.1362 755.7922 773.5879 831.5547
[2990,] 990.1512 1108.1454 1095.8528 991.9893
[2991,] 523.3464 506.4701 523.3247 598.2680
[2992,] 474.6263 501.7336 499.5597 477.1742
[2993,] 782.5966 831.5272 836.2033 823.2401
[2994,] 497.0407 588.5584 558.5727 429.2503
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[2996,] 628.8794 685.8813 676.6943 618.3517
[2997,] 905.8806 1068.3874 1031.2779 842.4471
[2998,] 413.5333 421.0642 425.4563 436.5330
[2999,] 573.1971 598.1351 599.4548 589.6346
[3000,] 399.2404 426.3878 422.1806 393.7432
[3001,] 349.6356 352.0638 356.6908 371.8260
[3002,] 551.9532 531.9715 550.7610 637.9021
[3003,] 636.3716 661.6869 666.4097 667.0402
[3004,] 935.5633 1040.9869 1030.6973 939.4873
[3005,] 694.5806 717.8236 727.4861 747.5797
[3006,] 1593.1193 1878.7976 1824.6565 1507.5662
[3007,] 841.5099 908.0911 908.6161 872.0204
[3008,] 346.9396 365.1442 363.1511 346.5660
[3009,] 1076.9147 1018.1676 1080.7372 1383.7616
[3010,] 1622.2223 1843.9887 1818.8042 1615.2091
[3011,] 473.9082 498.1854 497.1782 480.1735
[3012,] 456.7797 505.1563 493.4697 431.4615
[3013,] 740.5999 1013.9702 911.8661 593.6619
[3014,] 590.3916 593.5518 604.3407 643.0758
[3015,] 677.7049 681.5484 697.0702 756.6373
[3016,] 879.1622 1069.3477 1017.9176 786.4602
[3017,] 375.2554 360.9530 372.9151 429.4909
[3018,] 428.3978 477.1359 464.4869 400.7413
[3019,] 494.0513 535.8906 527.8821 479.5579
[3020,] 762.0746 887.8981 858.4168 711.1083
[3021,] 895.8541 985.2921 979.2240 909.9618
[3022,] 404.2171 394.1301 405.3017 454.3324
[3023,] 463.1987 450.4700 464.3193 523.9837
[3024,] 2228.0706 1445.2349 1801.3660 4274.9784
[3025,] 512.0766 525.5143 529.8898 537.2893
[3026,] 2619.2189 2785.9046 2813.1802 2811.8871
[3027,] 353.2335 392.8494 381.7446 328.8330
[3028,] 565.4353 567.1825 577.6593 615.0250
[3029,] 688.6359 767.2280 752.7089 670.3331
[3030,] 218.8425 225.4274 224.7337 218.7524
[3031,] 367.9129 378.5682 380.3443 380.2633
[3032,] 726.7637 837.6048 811.8513 684.4656
[3033,] 488.8334 520.7293 516.8460 486.4186
[3034,] 3722.4742 4020.3905 4005.4323 3791.0636
[3035,] 488.9753 511.5738 511.6051 498.9753
[3036,] 811.1813 870.0650 872.2214 845.6878
[3037,] 770.5170 831.0590 830.2278 792.9487
[3038,] 519.8736 570.1312 559.1586 497.7704
[3039,] 507.5773 598.6643 569.0664 441.0314
[3040,] 527.4711 580.5412 568.5567 502.7733
[3041,] 968.9330 1085.6876 1072.6369 967.6404
[3042,] 762.0693 884.1620 856.3849 714.5740
[3043,] 660.6665 659.6996 676.5913 743.0401
[3044,] 625.5048 744.1222 706.0970 560.8157
[3045,] 831.2302 826.2717 855.0814 969.6042
[3046,] 457.4827 498.9635 490.2575 440.3556
[3047,] 733.0712 847.2894 820.6607 688.7353
[3048,] 466.7665 497.0618 493.3517 464.4040
[3049,] 601.7401 619.7831 625.2798 633.3550
[3050,] 463.6889 506.9409 497.6471 444.8947
[3051,] 3045.9133 3241.1599 3266.2197 3245.2799
[3052,] 1156.1126 1138.3884 1189.9301 1399.0909
[3053,] 604.8704 583.2082 604.2536 711.9492
[3054,] 502.0876 518.6457 521.4833 521.7310
[3055,] 813.3462 848.2722 860.3978 882.2205
[3056,] 467.0498 523.8605 508.7473 432.8656
[3057,] 317.6002 282.6799 299.9946 416.0791
[3058,] 738.5245 825.9759 811.5517 722.0879
[3059,] 817.1401 907.0921 896.3881 813.4773
[3060,] 862.3668 1050.0334 998.4060 769.0934
[3061,] 747.0920 766.4646 781.3756 823.3984
[3062,] 1453.4176 1654.6842 1629.2161 1438.9257
[3063,] 600.7592 612.4818 620.4156 641.5940
[3064,] 725.9346 738.9373 754.3954 804.4933
[3065,] 744.6634 808.1279 804.6632 757.4174
[3066,] 449.0425 468.3961 468.8659 459.4865
[3067,] 509.3743 552.9558 544.5846 494.2517
[3068,] 627.1448 637.5013 647.2447 678.3052
[3069,] 356.8181 366.8489 368.5674 368.6997
[3070,] 868.1176 1003.0842 975.4212 825.0435
[3071,] 845.1274 916.3781 915.1523 870.3952
[3072,] 408.8153 412.9982 418.6516 436.2921
[3073,] 467.3692 477.0177 481.9318 493.5063
[3074,] 925.1767 1020.9077 1014.0536 938.3649
[3075,] 1228.8868 1547.1710 1459.6454 1056.9491
[3076,] 499.5208 510.7351 515.7148 526.5733
[3077,] 890.1014 975.5242 970.7876 907.8262
[3078,] 382.6649 386.5510 391.5144 406.9949
[3079,] 517.5693 527.0802 533.2055 549.1491
[3080,] 426.1079 440.6508 442.5162 440.5675
[3081,] 427.6660 487.9560 470.2051 387.8039
[3082,] 5825.3954 6199.6950 6156.0845 5790.9778
[3083,] 777.3977 931.0061 889.5287 703.3114
[3084,] 763.3477 898.4323 864.7542 704.0741
[3085,] 689.6975 747.4814 742.4272 693.6401
[3086,] 457.8452 485.2240 482.5389 458.4241
[3087,] 469.5936 463.1517 474.6531 520.6500
[3088,] 2077.9184 2398.8067 2347.7788 2012.5981
[3089,] 741.7031 844.6374 823.7987 710.0918
[3090,] 474.2263 487.0095 490.7905 496.5057
[3091,] 1987.8071 2445.2338 2331.1769 1753.7069
[3092,] 412.6621 437.3938 434.6077 411.8046
[3093,] 900.7973 928.9326 948.3199 1002.2006
[3094,] 546.1691 544.4338 555.8325 598.6226
[3095,] 698.7541 829.4989 792.8071 636.7953
[3096,] 1028.3460 1103.2308 1111.3231 1094.6727
[3097,] 590.3867 618.0260 618.8963 605.8161
[3098,] 730.5712 757.2596 767.9749 788.9464
[3099,] 487.9393 493.4504 500.5316 522.3004
[3100,] 382.2370 398.8350 398.5719 388.2910
[3101,] 481.7760 498.5634 500.8586 499.1628
[3102,] 784.2256 862.0687 854.7193 787.9283
[3103,] 603.0675 671.0384 654.6580 575.6674
[3104,] 608.5087 639.1096 639.7953 624.4888
[3105,] 1778.8664 2191.8726 2089.8571 1576.8797
[3106,] 672.8082 696.7397 704.5487 716.5638
[3107,] 580.0960 595.9857 601.2943 610.4961
[3108,] 619.5349 671.7912 663.8908 612.2603
[3109,] 405.7309 416.0817 419.1106 423.5934
[3110,] 681.5973 762.3406 746.2411 658.9345
[3111,] 475.2273 508.2783 503.6039 470.0652
[3112,] 655.7613 776.6463 740.2169 595.9929
[3113,] 846.7403 966.3675 944.5888 814.8069
[3114,] 820.7443 949.0001 921.9291 775.8953
[3115,] 703.9205 824.5962 792.9144 649.7987
[3116,] 523.2469 579.9167 566.2560 493.9650
[3117,] 494.2781 534.4248 527.1467 481.8950
[3118,] 703.3920 784.7416 770.4966 685.7928
[3119,] 476.8317 519.4126 510.7005 459.8935
[3120,] 633.1642 859.0805 767.3671 506.8932
[3121,] 391.6488 414.5335 411.8998 390.6765
[3122,] 756.0417 831.0378 823.3010 757.4778
[3123,] 700.6026 720.5287 731.8373 760.9889
[3124,] 533.5423 611.3191 588.4325 482.6329
[3125,] 636.0336 609.6169 634.0130 765.5547
[3126,] 1577.1023 1351.5343 1497.6346 2339.5794
[3127,] 345.0930 354.7576 356.2923 356.0069
[3128,] 401.2397 400.8930 408.0918 434.7103
[3129,] 6616.8321 6933.9015 6893.5200 6576.6137
[3130,] 566.0509 743.8149 670.0992 448.2473
[3131,] 519.2821 576.1329 562.2846 489.4062
[3132,] 1061.5971 1185.1159 1174.9015 1072.9485
[3133,] 397.3937 399.0881 405.3741 427.1234
[3134,] 623.7576 668.4138 664.0717 626.0640
[3135,] 472.0435 506.6567 501.2496 464.5995
[3136,] 562.9733 589.5703 589.8384 575.5994
[3137,] 1344.9954 1656.8826 1577.2199 1192.2611
[3138,] 746.2479 820.2138 812.2838 746.6903
[3139,] 563.1319 551.1059 567.0443 636.5647
[3140,] 1299.7918 1378.5442 1397.3166 1415.8980
[3141,] 537.5985 648.0524 609.3367 457.7819
[3142,] 634.3281 631.8695 646.9871 710.8140
[3143,] 840.7691 897.8768 902.3017 883.6106
[3144,] 527.0539 517.1964 531.3706 590.3038
[3145,] 1251.1982 1536.3614 1464.7571 1112.4625
[3146,] 738.8577 764.8481 776.4623 801.4968
[3147,] 527.4639 619.2803 589.7003 462.2854
[3148,] 606.2762 653.9262 647.1980 600.4568
[3149,] 975.1776 1013.7354 1033.5613 1081.3742
[3150,] 293.5012 275.1551 285.6729 348.9219
[3151,] 764.9653 856.4341 842.1620 748.7313
[3152,] 1302.4963 1627.5589 1539.7304 1130.6397
[3153,] 444.2972 491.0949 479.7509 419.9030
[3154,] 381.6543 396.5125 396.9586 389.9733
[3155,] 960.9601 1030.4432 1036.8725 1018.2179
[3156,] 573.4626 620.0643 612.0611 562.4184
[3157,] 564.7196 598.0314 595.5451 568.7659
[3158,] 679.0646 735.2999 730.1092 682.2508
[3159,] 952.6847 1040.7116 1038.8837 982.5162
[3160,] 486.2225 522.1967 516.5235 478.3387
[3161,] 1693.7312 2041.5609 1966.2996 1553.2504
[3162,] 526.5686 574.3744 564.6383 508.0356
[3163,] 436.5640 445.0487 449.6746 460.9817
[3164,] 514.0167 546.4701 542.9580 513.3926
[3165,] 508.0261 552.6588 543.8014 491.4789
[3166,] 1808.0602 2121.6144 2064.7827 1717.5710
[3167,] 840.2869 937.4490 924.9794 832.7133
[3168,] 4458.1130 4566.0979 4629.1416 4787.1508
[3169,] 608.1644 634.3955 636.8798 630.0720
[3170,] 584.5780 638.5018 627.9022 567.5103
[3171,] 562.8339 681.5687 638.9350 482.2260
[3172,] 532.9648 525.6930 538.9859 592.6695
[3173,] 448.9004 513.9371 494.7457 405.0878
[3174,] 811.2060 852.0139 861.6372 871.0276
[3175,] 341.3970 366.5015 361.3855 331.8981
[3176,] 660.3003 609.7966 643.7747 864.5968
[3177,] 440.4105 460.1361 460.2208 449.3348
[3178,] 4463.5203 4880.2434 4814.2971 4373.0922
[3179,] 641.3494 753.3867 720.2086 584.8332
[3180,] 544.7760 567.1376 568.6397 561.0107
[3181,] 503.4834 486.2982 502.8374 576.2108
[3182,] 1753.1415 1958.5564 1945.8041 1789.3599
[3183,] 667.9166 707.9978 708.7825 687.9669
[3184,] 626.7886 694.5770 680.5817 604.7135
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[3186,] 523.5028 547.6079 547.8452 535.0093
[3187,] 1418.7886 1637.5642 1602.8057 1377.2739
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[3189,] 851.7278 1072.2671 1004.5534 731.4178
[3190,] 587.0834 616.2948 616.3200 599.8404
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[3192,] 724.4635 711.9097 737.0211 849.6530
[3193,] 445.2689 500.4098 485.4497 411.6703
[3194,] 440.9123 453.4000 456.5050 460.0006
[3195,] 407.7325 389.7509 404.1049 472.5621
[3196,] 557.1375 561.8431 570.9151 600.8907
[3197,] 1374.1141 1478.3558 1490.0239 1469.3230
[3198,] 438.6496 469.4637 464.8270 432.8771
[3199,] 473.3916 587.1146 546.2299 386.0079
[3200,] 520.8370 571.1777 560.1952 498.7329
[3201,] 547.5658 505.0310 532.3858 682.3832
[3202,] 346.0430 346.1469 351.6040 371.3913
[3203,] 1290.1831 1689.5602 1566.7286 1053.0669
[3204,] 454.7562 477.5212 476.7055 461.1726
[3205,] 465.9600 491.4495 489.7486 469.8300
[3206,] 540.4197 708.9676 639.1204 422.2678
[3207,] 391.2891 342.3977 367.4423 524.1645
[3208,] 564.7635 585.9787 588.5496 584.9827
[3209,] 591.4211 626.7922 624.4836 597.3195
[3210,] 421.0312 447.0335 443.9516 419.4737
[3211,] 781.3169 884.0252 865.8506 755.4794
[3212,] 735.9933 972.2151 888.3535 607.3177
[3213,] 380.0624 366.2540 378.1353 433.9754
[3214,] 1286.0301 1366.6879 1384.1795 1397.3421
[3215,] 368.8281 397.9301 391.8985 357.5747
[3216,] 772.7742 862.3200 849.3222 760.2794
[3217,] 512.4453 544.0422 540.8519 512.7722
[3218,] 1358.8777 1480.4852 1484.2776 1427.3223
[3219,] 1773.0908 1911.9730 1927.8072 1900.5159
[3220,] 804.0577 1070.0448 976.5720 654.2720
[3221,] 479.5556 467.1639 481.2592 541.4620
[3222,] 627.9856 719.4889 694.1919 585.1396
[3223,] 361.9526 349.2551 360.1944 411.4340
[3224,] 547.9813 606.5489 592.6541 519.3664
[3225,] 591.0180 623.2876 622.2582 600.7013
[3226,] 914.6608 884.9001 927.6233 1124.2791
[3227,] 529.0662 552.1811 552.9708 542.5280
[3228,] 544.4549 629.7080 603.3656 488.0680
[3229,] 746.7473 811.2110 807.4868 758.9651
[3230,] 772.9297 849.7642 842.1995 775.5502
[3231,] 543.3472 594.2160 583.4840 523.0353
[3232,] 1325.6662 1592.9693 1532.4000 1214.4836
[3233,] 565.7176 600.0292 597.1571 568.6099
[3234,] 617.5415 668.2473 660.8516 611.5885
[3235,] 2307.1790 2600.9918 2568.4963 2299.1868
[3236,] 606.0041 615.8134 624.9256 651.0584
[3237,] 817.4933 924.0160 906.2183 795.2152
[3238,] 3164.3237 9158.0668 6827.5697 376.6829
[3239,] 409.9726 447.3376 439.0783 393.5061
[3240,] 712.3811 723.1157 738.5528 791.1650
[3241,] 551.0396 570.9221 573.6132 571.4421
[3242,] 460.0946 447.5903 461.2664 520.2242
[3243,] 486.6991 513.0566 511.4627 491.3882
[3244,] 604.6096 604.2980 616.9923 667.5409
[3245,] 365.8797 378.0479 379.1353 375.8166
[3246,] 503.1761 535.1981 531.5920 501.9918
[3247,] 466.3295 454.2921 467.9445 526.2606
[3248,] 740.7621 759.3437 774.1029 815.4838
[3249,] 940.8949 1036.6596 1030.8096 957.7120
[3250,] 730.6649 694.7358 729.0006 907.4581
[3251,] 609.6011 533.5991 574.7356 888.1941
[3252,] 617.5052 675.3501 664.8985 604.0754
[3253,] 2010.7771 2242.7241 2227.6690 2046.7617
[3254,] 815.7125 856.5340 866.3475 876.4111
[3255,] 445.6605 452.9589 458.3225 472.8924
[3256,] 397.2830 402.6461 407.4330 421.3655
[3257,] 812.0738 891.6605 885.0784 819.9394
[3258,] 562.1129 583.1991 585.7310 582.0782
[3259,] 1275.8477 1478.6541 1444.4278 1227.9347
[3260,] 434.5916 476.4850 466.9895 415.0795
[3261,] 489.0657 524.7764 519.2786 481.7731
[3262,] 3560.2057 3788.4626 3804.0375 3725.4303
[3263,] 1123.4302 1237.9502 1234.6150 1158.6848
[3264,] 552.7243 634.2832 609.7396 501.2629
[3265,] 1212.6902 813.6232 984.2003 2677.6546
[3266,] 862.3727 1589.2560 1263.6177 541.5154
[3267,] 660.2067 668.4418 681.6247 726.5200
[3268,] 371.0831 406.6360 397.9124 352.7326
[3269,] 418.0572 432.5396 434.2010 431.5372
[3270,] 424.4108 447.1590 445.5476 427.4585
[3271,] 425.9666 435.8152 439.6167 447.1116
[3272,] 1083.5608 1207.0373 1197.9570 1099.4223
[3273,] 1438.7518 1716.4199 1656.8254 1336.2820
[3274,] 1805.5465 2021.5706 2006.6459 1835.1765
[3275,] 518.1340 528.3157 534.1802 548.7876
[3276,] 1040.7513 980.4752 1041.6494 1343.7979
[3277,] 368.4682 410.5229 398.8430 342.8839
[3278,] 439.7903 405.7751 427.0907 538.1938
[3279,] 1041.7319 1493.1197 1332.4486 776.3057
[3280,] 350.0947 356.6843 359.6156 366.0952
[3281,] 707.5403 844.9908 805.6998 640.8434
[3282,] 834.1553 1048.6508 982.3449 717.2380
[3283,] 535.8840 603.1823 585.0206 496.2744
[3284,] 611.5394 646.8022 645.7170 622.0975
[3285,] 1991.5996 2296.5453 2249.6464 1931.6113
[3286,] 494.9687 644.9556 585.8994 382.2562
[3287,] 2545.7822 2747.0832 2758.8749 2687.6569
[3288,] 388.1944 405.4879 405.1158 394.1074
[3289,] 613.1504 592.1867 613.1726 722.5695
[3290,] 824.4759 966.4087 933.5313 766.3600
[3291,] 917.6909 868.3835 918.3651 1170.2124
[3292,] 864.7227 918.1732 925.4426 918.8603
[3293,] 438.4452 417.5390 433.8801 511.4095
[3294,] 479.0483 499.7435 500.3535 490.7055
[3295,] 762.3987 802.9192 809.8446 810.0606
[3296,] 712.5890 921.3012 848.7440 599.8927
[3297,] 718.0639 745.0636 754.5734 771.5877
[3298,] 632.8862 644.7392 654.2357 683.0141
[3299,] 483.9815 511.2449 509.2104 487.2033
[3300,] 426.5352 513.3908 483.6428 362.1361
[3301,] 443.7867 469.6937 467.2735 444.8569
[3302,] 1061.6513 1201.8162 1184.5077 1053.0237
[3303,] 369.6181 367.0816 374.2340 402.3902
[3304,] 1009.8682 1122.7033 1113.8055 1022.2929
[3305,] 758.5393 829.9791 823.8903 764.8148
[3306,] 643.0873 700.8176 692.2834 635.5727
[3307,] 965.9183 1098.1078 1078.2359 946.7669
[3308,] 517.3242 565.4377 555.3214 497.5250
[3309,] 297.3533 282.7473 292.4487 343.7053
[3310,] 634.0039 680.1253 675.9720 637.1579
[3311,] 382.2927 378.1183 386.3208 419.4848
[3312,] 787.3899 722.8923 770.4992 1045.9463
[3313,] 646.4388 678.4848 681.2141 671.7694
[3314,] 581.2038 622.0990 616.8565 578.4084
[3315,] 383.6797 438.8533 421.8157 346.3717
[3316,] 432.5933 462.5373 458.1070 427.3147
[3317,] 864.4666 907.5783 919.0777 933.3323
[3318,] 1886.8249 2257.4242 2179.6117 1740.0015
[3319,] 472.1321 484.1716 488.2111 495.2711
[3320,] 568.9106 612.9638 606.0771 559.9799
[3321,] 1751.9739 2018.3325 1980.5282 1710.7911
[3322,] 655.5111 696.0486 695.8061 672.0317
[3323,] 1371.1580 1660.6005 1592.3651 1245.1305
[3324,] 1585.7872 1959.4924 1865.7718 1408.9375
[3325,] 780.8481 886.1906 866.8155 752.0541
[3326,] 535.6833 548.4635 553.6960 564.5148
[3327,] 157.9761 161.1156 160.7969 157.9761
[3328,] 574.2202 618.4180 611.5292 566.0881
[3329,] 2005.4091 2312.3685 2265.0447 1945.5238
[3330,] 823.4058 905.6878 898.5964 830.2845
[3331,] 749.8897 844.9290 828.2544 728.3468
[3332,] 610.3451 649.1201 646.4886 615.8968
[3333,] 446.2260 450.3810 457.0402 478.2366
[3334,] 540.3472 572.4731 569.7730 542.9182
[3335,] 2176.0715 2476.0669 2438.4187 2145.5315
[3336,] 708.3966 752.1013 754.1777 735.3689
[3337,] 423.7112 462.2186 453.8518 407.1439
[3338,] 514.8452 543.2192 541.4479 519.6646
[3339,] 453.9169 477.3350 476.2260 459.3709
[3340,] 862.7995 1074.0440 1011.5480 750.0929
[3341,] 1076.1037 1189.5731 1184.3525 1103.1747
[3342,] 495.7582 508.8527 512.9757 519.7136
[3343,] 304.6906 303.6959 308.4106 326.8072
[3344,] 1411.6426 1569.9116 1560.7305 1442.0104
[3345,] 355.2742 365.4942 367.0912 366.6834
[3346,] 633.4615 771.4069 724.6262 557.2566
[3347,] 248.8812 284.8814 270.9734 218.3345
[3348,] 360.6396 575.4727 477.7024 243.2487
[3349,] 381.8048 392.5005 394.6810 395.9597
[3350,] 465.6079 514.4319 502.7745 440.3877
[3351,] 768.8088 824.5872 825.6517 797.0331
[3352,] 4568.2013 4955.9560 4905.4041 4527.6680
[3353,] 1179.4029 1320.0710 1308.6016 1192.0578
[3354,] 681.5552 756.6143 743.2152 664.6006
[3355,] 583.4282 629.5124 622.2030 575.0277
[3356,] 689.5193 789.3449 765.6780 650.9400
[3357,] 583.0496 775.5486 694.6625 462.1303
[3358,] 1364.1243 1545.7752 1524.4601 1356.6037
[3359,] 850.0031 959.2151 942.1333 830.3851
[3360,] 535.0792 560.5696 560.5200 545.9500
[3361,] 549.0805 548.0764 559.2560 600.7629
[3362,] 929.0102 1124.8609 1073.8846 839.0511
[3363,] 437.7637 478.8857 469.8149 419.4079
[3364,] 594.7935 659.1247 644.2509 568.7257
[3365,] 526.8523 512.7407 528.5940 597.3951
[3366,] 1405.0424 1639.1734 1597.0714 1343.8900
[3367,] 390.0396 448.1346 430.0086 350.4095
[3368,] 522.4693 554.5830 551.4293 523.1713
[3369,] 1503.6796 1906.2511 1795.3980 1289.3401
[3370,] 2019.3636 2159.4615 2183.3250 2182.8902
[3371,] 568.3729 625.5959 612.6351 544.5126
[3372,] 1153.0885 1220.5797 1238.1508 1259.3273
[3373,] 398.7074 435.1331 426.8940 382.1523
[3374,] 442.3568 451.0215 455.7381 467.1653
[3375,] 1285.8065 1422.9174 1416.9772 1320.2974
[3376,] 1494.5338 2193.9497 1945.7010 1050.9892
[3377,] 1591.5607 1825.7958 1793.9545 1564.3799
[3378,] 954.9548 1127.8913 1089.3165 890.9570
[3379,] 887.3478 975.0841 969.1981 901.5944
[3380,] 675.4806 734.1189 727.6450 674.9913
[3381,] 547.8193 571.9685 572.8036 561.9254
[3382,] 1095.6161 1231.1506 1217.5467 1098.8968
[3383,] 5149.7043 5613.7806 5542.1552 5046.5091
[3384,] 430.3598 449.0121 449.2833 439.6496bleh <- (vobj$E* sqrt(vobj$weights)) %>% sqrt()
Meta Samples Ind Rep Cond Cond_Ind
S1 S1 B_77 Bio Dox B_77_Dox
S3 S3 C_87 Bio Dox C_87_Dox
S5 S5 A_48 Tech Dox A_48_Dox
S7 S7 A_48 Tech Dox A_48_Dox
S9 S9 A_48 Tech Dox A_48_Dox
S2 S2 B_77 Bio Control B_77_Control
S4 S4 C_87 Bio Control C_87_Control
S6 S6 A_48 Tech Control A_48_Control
S8 S8 A_48 Tech Control A_48_Control
S10 S10 A_48 Tech Control A_48_Control# Before correction:
prcomp_res <- prcomp(t(vobj$E), scale. = TRUE, center = TRUE, )
ggplot2::autoplot(prcomp_res, data = Meta, colour = "Cond", shape = "Ind", size =4)+
theme_bw()
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# After correction:
prcomp_res <- prcomp(t(bleh), scale. = TRUE, center = TRUE)
ggplot2::autoplot(prcomp_res, data = Meta, colour = "Cond", shape = "Ind", size =4)+
theme_bw()
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Heatmaps
Before correction with weights
hypothetical_1 <- vobj$E
colnames(hypothetical_1) <- Meta$Cond_Ind
# Use paste to combine the vectors
colnames(hypothetical_1) <- Meta$Cond_Ind
pheatmap::pheatmap(hypothetical_1,
cluster_rows = TRUE,
cluster_cols = TRUE,
show_rownames = FALSE,
show_colnames = TRUE
)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
cor(hypothetical_1) %>% pheatmap(
cluster_rows = TRUE,
cluster_cols = TRUE,
show_rownames = TRUE,
show_colnames = TRUE)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# After correction with weights
hypothetical_2 <- bleh
# Use paste to combine the vectors
colnames(hypothetical_2) <- Meta$Cond_Ind
pheatmap::pheatmap(hypothetical_2,
cluster_rows = TRUE,
cluster_cols = TRUE,
show_rownames = FALSE,
show_colnames = TRUE
)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
cor(hypothetical_2) %>% pheatmap(
cluster_rows = TRUE,
cluster_cols = TRUE,
show_rownames = TRUE,
show_colnames = TRUE)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Volcano with adj. P
# 1. Create a column to threshold adjusted P-values/q-values
toptable_Threshold_0.05 <- toptable_Dupcor %>% mutate(threshold_P = adj.P.Val < 0.05)
toptable_Threshold_0.05 logFC AveExpr t P.Value adj.P.Val
Q15327 -3.5538167761 23.99047 -16.743392583 2.054348e-08 6.951913e-05
O76021 -2.1410928975 24.25375 -13.552273075 1.444049e-07 2.443330e-04
Q96LW7 -1.6342957224 19.97143 -12.658156240 2.690260e-07 3.034614e-04
Q969Q1 -4.3423803749 20.84232 -11.920968346 4.632261e-07 3.918893e-04
P19388 -1.1658966201 20.44496 -11.622278836 5.822611e-07 3.940743e-04
Q96GQ7 -1.7622803092 20.67219 -10.833687964 1.092754e-06 6.163133e-04
O43159 -2.1096892264 20.56152 -10.318875713 1.684397e-06 8.142856e-04
Q6EMK4 2.3724491682 21.06129 9.656663573 3.021583e-06 1.278129e-03
P17844 -1.1425406345 25.94182 -9.304080076 4.181540e-06 1.572259e-03
Q96PU8 -2.1455298252 21.20691 -8.951039111 5.848963e-06 1.881965e-03
Q14498 -0.8019789647 23.53525 -8.890645629 6.201192e-06 1.881965e-03
P67809 -1.1045436713 26.08944 -8.774842757 6.943236e-06 1.881965e-03
Q9BQG0 -2.2554253126 23.65243 -8.733704263 7.229772e-06 1.881965e-03
P17480 0.7861550384 24.19823 8.375813153 1.034545e-05 2.500644e-03
Q13641 1.3614453777 21.17736 8.173707956 1.273359e-05 2.711717e-03
P48634 -1.0858313049 20.62697 -8.167089200 1.282136e-05 2.711717e-03
Q92841 -0.7539368895 27.56259 -8.106875865 1.365082e-05 2.717316e-03
Q4G0J3 -0.7752299178 23.21486 -7.930348626 1.643911e-05 3.007123e-03
P78347 -0.7435322555 26.03868 -7.905231639 1.688397e-05 3.007123e-03
Q02818 -2.3955560537 22.73869 -7.799179727 1.891244e-05 3.156765e-03
Q00341 -0.9058215272 24.57254 -7.751362535 1.991267e-05 3.156765e-03
Q13123 -1.1338838135 22.25040 -7.723467328 2.052270e-05 3.156765e-03
Q92522 -1.6536207267 24.17315 -7.487060032 2.659124e-05 3.912381e-03
Q14980 -1.2192370415 24.62561 -7.396873728 2.940013e-05 4.145419e-03
Q14694 -0.7674689571 22.72482 -7.315811636 3.220183e-05 4.358840e-03
Q2TAY7 -0.7632109180 23.97921 -7.246263013 3.483785e-05 4.534280e-03
Q9NR30 -1.0206069551 23.97933 -7.190152266 3.713578e-05 4.654352e-03
O60427 -1.2083869980 21.17097 -7.066908229 4.278320e-05 5.057106e-03
Q9P258 1.7059490390 21.25515 7.027127742 4.480026e-05 5.057106e-03
Q9Y6M5 1.1382005458 23.05230 6.992690129 4.662999e-05 5.057106e-03
Q9BVP2 -1.5081799250 21.49507 -6.984110085 4.709839e-05 5.057106e-03
Q9P0V3 -1.5653815562 20.47551 -6.971047875 4.782133e-05 5.057106e-03
Q6P5R6 -1.8797159229 20.65233 -6.877412686 5.337046e-05 5.472898e-03
Q92934 -1.2351650877 21.23559 -6.837172761 5.596677e-05 5.521477e-03
Q86XP3 -0.7285835498 23.65238 -6.820129601 5.710747e-05 5.521477e-03
O95864 -2.6174073619 19.59627 -6.761650756 6.121744e-05 5.610083e-03
Q9NZB2 -1.0158315089 23.24048 -6.739923968 6.282530e-05 5.610083e-03
Q9UQE7 -1.4794349461 20.76312 -6.737634433 6.299739e-05 5.610083e-03
Q6P1J9 -0.7979336434 22.49594 -6.581727353 7.601030e-05 6.595355e-03
P16989 -2.7782295557 21.60829 -6.515400547 8.240654e-05 6.971593e-03
Q9BZK7 -0.6448869669 22.87123 -6.451002969 8.917833e-05 7.360475e-03
P08865 -0.6951266140 26.40427 -6.412174570 9.355111e-05 7.537546e-03
P26640 0.5742911993 24.75172 6.360867386 9.968907e-05 7.845298e-03
Q96T58 1.2393881736 22.45091 6.330081073 1.035805e-04 7.847079e-03
Q13151 -0.7134418171 25.34094 -6.319602357 1.049423e-04 7.847079e-03
Q9Y2X3 0.6514755296 25.29422 6.306530078 1.066683e-04 7.847079e-03
Q13451 0.7026843452 19.60808 6.254442541 1.138575e-04 8.197740e-03
Q9UKA9 -0.7576536433 24.34593 -6.213200990 1.199217e-04 8.454480e-03
P23434 0.9639278116 22.27141 6.180102278 1.250414e-04 8.635514e-03
Q9Y333 -1.6242843304 20.77853 -6.096218482 1.391064e-04 9.414723e-03
Q53EP0 -1.4507298032 22.03019 -6.016564592 1.540564e-04 1.022209e-02
P62906 -0.9477995132 25.76636 -5.964830968 1.646908e-04 1.029373e-02
P49711 -0.7460068993 21.19290 -5.956844911 1.664019e-04 1.029373e-02
P42285 -0.9617635928 22.20386 -5.956134822 1.665550e-04 1.029373e-02
Q16718 -0.6128746798 22.93208 -5.952672315 1.673036e-04 1.029373e-02
P62854 -1.7373368214 24.65941 -5.893289295 1.807240e-04 1.086007e-02
Q9BQ39 -1.1157407297 22.97953 -5.878742237 1.841859e-04 1.086007e-02
P62750 -1.1141546927 24.69063 -5.870677397 1.861359e-04 1.086007e-02
Q9H2P0 -1.0743673769 22.07434 -5.826142783 1.973134e-04 1.116432e-02
Q49A26 0.8520902429 22.17348 5.820374572 1.988134e-04 1.116432e-02
Q9UQB8 1.1594641852 22.29025 5.811110965 2.012480e-04 1.116432e-02
Q96L96 -1.7454620125 20.94368 -5.758472970 2.157071e-04 1.177343e-02
P62753 -0.6301099885 25.90518 -5.711233343 2.296400e-04 1.233495e-02
P16403 -1.5769850831 25.04572 -5.631674350 2.553465e-04 1.325802e-02
P62273 -0.7268629014 22.25772 -5.625972328 2.573044e-04 1.325802e-02
Q99536 0.7708229050 24.87540 5.615690534 2.608759e-04 1.325802e-02
Q06136 0.7405558040 19.15135 5.611075774 2.624962e-04 1.325802e-02
Q9UQ35 -0.5903700138 25.26477 -5.573735521 2.760127e-04 1.326771e-02
Q96RU2 -0.8072247663 23.68337 -5.571357558 2.768985e-04 1.326771e-02
P61254 -0.8148623788 26.21498 -5.566482938 2.787240e-04 1.326771e-02
Q14728 0.7768860215 22.43873 5.557469579 2.821334e-04 1.326771e-02
Q9H1E3 0.9093433795 22.40193 5.557054139 2.822917e-04 1.326771e-02
Q86U42 -0.6371784527 23.71794 -5.532265108 2.919081e-04 1.333621e-02
P61313 -0.5116069160 26.06643 -5.517749351 2.977024e-04 1.333621e-02
Q01780 -1.8332257421 20.36588 -5.510269734 3.007363e-04 1.333621e-02
P46782 -0.7266249638 25.94201 -5.506860622 3.021302e-04 1.333621e-02
Q9HCM4 0.8163123746 21.15638 5.489766012 3.092251e-04 1.333621e-02
P30876 -1.0153940278 21.81690 -5.485330005 3.110953e-04 1.333621e-02
P39880 -0.6669134126 22.75124 -5.480032879 3.133446e-04 1.333621e-02
Q9NQT5 -0.9054903012 20.85469 -5.475515105 3.152768e-04 1.333621e-02
P62280 -0.6059548196 26.82509 -5.457854236 3.229539e-04 1.349230e-02
P62701 -0.5729549732 27.72801 -5.445743887 3.283343e-04 1.354980e-02
Q92747 0.6126517330 25.26208 5.393644668 3.526056e-04 1.424497e-02
P36578 -0.4568522015 27.13820 -5.391596241 3.535985e-04 1.424497e-02
P62888 -0.6160229343 25.39329 -5.380658805 3.589510e-04 1.429047e-02
Q5QJ74 -1.1986896135 19.32430 -5.359204512 3.697050e-04 1.448893e-02
O75787 1.6934062614 22.11598 5.353740006 3.724990e-04 1.448893e-02
P49207 -0.9596894143 24.07938 -5.324740422 3.877116e-04 1.490927e-02
Q9P0M6 1.6001832065 20.21988 5.298994257 4.017775e-04 1.511453e-02
Q6Y7W6 -0.9044508349 20.67539 -5.298626891 4.019821e-04 1.511453e-02
Q7Z739 -0.7250445918 22.34136 -5.290435679 4.065739e-04 1.511919e-02
Q8NC51 -0.8540143136 24.84415 -5.277441240 4.139742e-04 1.522705e-02
P18621 -0.6967076722 25.38760 -5.256153054 4.264122e-04 1.540433e-02
O00461 -0.4757964569 22.78785 -5.253654415 4.278982e-04 1.540433e-02
P46783 -0.9888508824 23.12357 -5.243981188 4.337036e-04 1.544898e-02
P19338 -0.5172166796 28.15254 -5.229140303 4.427755e-04 1.560784e-02
P53396 1.0062251308 23.59171 5.207466557 4.563918e-04 1.592196e-02
Q99459 -0.6906765081 23.61189 -5.195683317 4.639826e-04 1.602160e-02
Q9Y5S2 -0.5251120289 23.52634 -5.176242135 4.768042e-04 1.629803e-02
Q9Y2I6 0.5208548082 20.60037 5.133818920 5.061213e-04 1.712715e-02
O60292 1.2411170961 20.20225 5.101116493 5.300389e-04 1.754874e-02
P61513 -0.5882082097 24.74087 -5.099404478 5.313240e-04 1.754874e-02
Q13509 0.7849629140 23.62729 5.095671806 5.341373e-04 1.754874e-02
Q9NVP1 -0.6777723393 21.45817 -5.053570465 5.669987e-04 1.844926e-02
P62263 -0.6026084568 25.93120 -5.045741141 5.733451e-04 1.847809e-02
P16220 -0.5031254586 21.42924 -5.010477582 6.028879e-04 1.924691e-02
Q9UKU7 0.5589429736 25.14171 4.977675589 6.318350e-04 1.980493e-02
P34932 0.5788276899 26.06151 4.977413596 6.320721e-04 1.980493e-02
P83731 -0.5543597613 25.34323 -4.964228741 6.441284e-04 1.999753e-02
P62249 -0.6667823795 26.00658 -4.957101489 6.507479e-04 2.001937e-02
P25398 -0.5878505606 24.66965 -4.923122220 6.833226e-04 2.030277e-02
Q12983 -1.1241955717 20.54654 -4.922961512 6.834807e-04 2.030277e-02
P07996 -1.6006476533 22.35682 -4.918472487 6.879141e-04 2.030277e-02
Q14966 -0.7779107967 22.67750 -4.906104168 7.002888e-04 2.030277e-02
P17302 -1.1116578520 21.97051 -4.901817183 7.046334e-04 2.030277e-02
Q9UBG0 -1.0789245230 20.13330 -4.898600708 7.079121e-04 2.030277e-02
P55769 0.5414058709 22.45777 4.896410907 7.101535e-04 2.030277e-02
P21453 -1.0074850656 19.98293 -4.895586185 7.109997e-04 2.030277e-02
P15529 0.5800084020 22.29172 4.892712124 7.139568e-04 2.030277e-02
P83881 -0.7844961130 24.11681 -4.882535087 7.245342e-04 2.043186e-02
Q06830 0.5174185908 27.20340 4.869219439 7.386273e-04 2.062576e-02
Q9NUP9 -0.6427814586 22.72842 -4.864585594 7.436002e-04 2.062576e-02
P08708 -0.8002218256 24.15239 -4.837181731 7.737503e-04 2.117750e-02
P62269 -1.0084011844 26.28043 -4.833293840 7.781326e-04 2.117750e-02
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P29992 -0.0064416056 25.11985 -0.068711426 9.466323e-01 9.710227e-01
Q5T2T1 0.0097889222 19.07726 0.067750831 9.473772e-01 9.714922e-01
P62140 0.0079203715 26.50835 0.066117357 9.486438e-01 9.721262e-01
Q969V3 -0.0091642882 24.65837 -0.065961302 9.487649e-01 9.721262e-01
O75063 -0.0196776515 20.88879 -0.065731441 9.489431e-01 9.721262e-01
O43765 -0.0198025217 25.84904 -0.065471807 9.491445e-01 9.721262e-01
Q8N2F6 -0.0198511112 22.52100 -0.063289545 9.508370e-01 9.735650e-01
Q8WVX9 0.0060289228 18.79905 0.059937211 9.534375e-01 9.759324e-01
Q14139 -0.0057615311 22.36123 -0.057894924 9.550221e-01 9.772588e-01
P82933 0.0054829992 25.65392 0.056171698 9.563593e-01 9.781625e-01
Q01813 0.0167370873 27.35581 0.056011786 9.564834e-01 9.781625e-01
Q9BX66 0.0143358680 21.78936 0.055212659 9.571035e-01 9.783663e-01
P60891 0.0067843410 25.93807 0.054762504 9.574529e-01 9.783663e-01
P11021 0.0063562359 30.65990 0.054438581 9.577043e-01 9.783663e-01
Q9NSV4 0.0171790228 18.90526 0.054264910 9.578391e-01 9.783663e-01
P02786 0.0070610326 28.18432 0.053292307 9.585939e-01 9.788418e-01
Q15075 0.0050036274 26.59854 0.052648238 9.590938e-01 9.790569e-01
P50440 0.0143064229 23.95149 0.052212300 9.594322e-01 9.791069e-01
Q96ER9 -0.0102512056 22.44630 -0.051768147 9.597770e-01 9.791635e-01
Q9H0V9 -0.0093153054 23.67906 -0.051198399 9.602192e-01 9.793194e-01
Q96SJ8 -0.0156754084 21.16539 -0.049857987 9.612597e-01 9.800853e-01
Q9UDR5 0.0064776062 26.72489 0.047750841 9.628956e-01 9.812624e-01
Q99436 0.0067940073 24.84376 0.046876834 9.635742e-01 9.812624e-01
P07910 0.0061472861 25.80692 0.046681226 9.637261e-01 9.812624e-01
P43121 0.0072381493 25.74715 0.046638044 9.637596e-01 9.812624e-01
Q969Z3 -0.0054001601 25.20349 -0.046171842 9.641216e-01 9.812624e-01
Q9P291 0.0057158178 25.18091 0.046130028 9.641541e-01 9.812624e-01
Q96I51 -0.0099153320 22.36944 -0.045618276 9.645514e-01 9.813716e-01
P12270 -0.0063074599 25.52478 -0.045036686 9.650030e-01 9.814281e-01
P62993 -0.0191703184 21.93934 -0.044465395 9.654466e-01 9.814281e-01
O43852 -0.0066212747 26.73698 -0.044426234 9.654770e-01 9.814281e-01
O00186 -0.0047971737 24.18030 -0.041618048 9.676578e-01 9.833495e-01
P61020 0.0097273667 23.77504 0.041026201 9.681174e-01 9.835213e-01
Q9UJW0 -0.0059093156 21.61949 -0.039172094 9.695575e-01 9.846886e-01
P50213 -0.0051954398 29.24408 -0.038559279 9.700335e-01 9.848765e-01
P13861 -0.0050914180 25.47757 -0.037951567 9.705055e-01 9.850378e-01
Q8NDZ4 -0.0086632938 22.12834 -0.037303220 9.710091e-01 9.850378e-01
P35659 -0.0044616574 24.57097 -0.037053420 9.712032e-01 9.850378e-01
P56747 0.0187623726 22.70278 0.036814390 9.713888e-01 9.850378e-01
O95861 -0.0054869445 21.62864 -0.036481025 9.716478e-01 9.850378e-01
Q68D91 -0.0095284586 21.60360 -0.034982953 9.728115e-01 9.858407e-01
Q96D53 -0.0072857034 21.18247 -0.034343139 9.733086e-01 9.858407e-01
Q9GZP0 0.0175080541 19.10221 0.034336389 9.733138e-01 9.858407e-01
Q9UBX3 -0.0059197351 24.59611 -0.033774291 9.737505e-01 9.859879e-01
Q6Y288 0.0073062541 19.45079 0.033286033 9.741298e-01 9.860329e-01
Q58EX2 0.0102423104 20.21960 0.032597398 9.746648e-01 9.860329e-01
Q9P035 -0.0044522294 24.84269 -0.032591930 9.746690e-01 9.860329e-01
Q92614 -0.0028647118 27.76244 -0.032011880 9.751197e-01 9.861940e-01
O75376 0.0074416599 21.25635 0.031302942 9.756705e-01 9.864562e-01
O43615 0.0037622817 26.76185 0.030250962 9.764878e-01 9.867703e-01
O43169 0.0032027964 25.40996 0.030152532 9.765643e-01 9.867703e-01
Q6UW68 0.0046572920 24.02324 0.028940720 9.775059e-01 9.871844e-01
P35968 0.0047097694 22.81438 0.028874123 9.775576e-01 9.871844e-01
Q9GZY4 -0.0055021156 22.45684 -0.028419001 9.779113e-01 9.872469e-01
Q8IZQ5 0.0066248105 21.22786 0.027632841 9.785221e-01 9.874605e-01
O60841 -0.0035220559 23.29606 -0.027395651 9.787065e-01 9.874605e-01
P28288 -0.0036256509 25.16783 -0.026983209 9.790269e-01 9.874895e-01
O75417 0.0054159815 22.72883 0.024822018 9.807064e-01 9.888887e-01
Q15067 0.0044210791 24.49190 0.023960695 9.813757e-01 9.892688e-01
P26368 -0.0022281622 25.59537 -0.022554523 9.824685e-01 9.897040e-01
P23919 -0.0032968988 23.83964 -0.022524558 9.824918e-01 9.897040e-01
Q155Q3 0.0028108220 19.49408 0.021983738 9.829121e-01 9.897040e-01
Q13232 -0.0035464856 23.30546 -0.021899863 9.829773e-01 9.897040e-01
Q6FI81 0.0039575492 22.46627 0.021490816 9.832952e-01 9.897296e-01
O00505 0.0085658006 21.80293 0.019373553 9.849407e-01 9.910911e-01
Q15008 0.0024531736 24.84515 0.018699420 9.854646e-01 9.913235e-01
O00743 -0.0030229107 20.62747 -0.018142189 9.858977e-01 9.914644e-01
Q32P44 -0.0035448747 20.06958 -0.015770667 9.877410e-01 9.930230e-01
P78417 0.0018041193 23.56780 0.015101749 9.882609e-01 9.932506e-01
P14621 -0.0045005530 20.78173 -0.014573761 9.886713e-01 9.933680e-01
Q9BYD1 0.0015316464 24.46061 0.014116314 9.890268e-01 9.934303e-01
P61586 0.0013072005 26.74816 0.013411483 9.895747e-01 9.936857e-01
Q14566 0.0021581420 23.68538 0.012937085 9.899434e-01 9.937611e-01
P10915 0.0050398203 23.61243 0.012197305 9.905185e-01 9.940434e-01
Q9BXS5 -0.0015175385 22.77994 -0.009945018 9.922692e-01 9.955052e-01
Q6P1M0 -0.0013230822 22.76586 -0.009290689 9.927778e-01 9.955410e-01
Q9C0D5 0.0037181052 19.95329 0.009142181 9.928933e-01 9.955410e-01
Q15185 0.0008048923 24.10663 0.008508503 9.933859e-01 9.955435e-01
P51153 0.0012681861 22.33613 0.008381986 9.934842e-01 9.955435e-01
P29144 0.0012070742 25.09501 0.007639958 9.940610e-01 9.958267e-01
P09543 0.0006074187 25.46963 0.004251034 9.966954e-01 9.981702e-01
Q9BZF1 -0.0006529423 22.69373 -0.002977151 9.976857e-01 9.988664e-01
Q92538 0.0002573516 22.84061 0.002240344 9.982584e-01 9.991413e-01
Q96N64 -0.0002124377 21.72457 -0.001860990 9.985533e-01 9.991413e-01
Q52LJ0 -0.0003543919 23.01653 -0.001309060 9.989824e-01 9.991413e-01
P54753 -0.0002160733 24.88610 -0.001104627 9.991413e-01 9.991413e-01
B Protein adj_q_values threshold_P
Q15327 9.41678906 Q15327 3.487221e-05 TRUE
O76021 7.85938218 O76021 1.225624e-04 TRUE
Q96LW7 7.32858329 Q96LW7 1.522224e-04 TRUE
Q969Q1 6.85315287 Q969Q1 1.965796e-04 TRUE
P19388 6.64995911 P19388 1.976757e-04 TRUE
Q96GQ7 6.08177746 Q96GQ7 3.091553e-04 TRUE
O43159 5.68418526 O43159 4.084622e-04 TRUE
Q6EMK4 5.13889238 Q6EMK4 6.411357e-04 TRUE
P17844 4.83188794 P17844 7.886770e-04 TRUE
Q96PU8 4.51212370 Q96PU8 9.440320e-04 TRUE
Q14498 4.45613928 Q14498 9.440320e-04 TRUE
P67809 4.34771600 P67809 9.440320e-04 TRUE
Q9BQG0 4.30885560 Q9BQG0 9.440320e-04 TRUE
P17480 3.96300337 P17480 1.254374e-03 TRUE
Q13641 3.76135899 Q13641 1.360252e-03 TRUE
P48634 3.75467595 P48634 1.360252e-03 TRUE
Q92841 3.69364382 Q92841 1.363061e-03 TRUE
Q4G0J3 3.51225902 Q4G0J3 1.508434e-03 TRUE
P78347 3.48614960 P78347 1.508434e-03 TRUE
Q02818 3.37506845 Q02818 1.583497e-03 TRUE
Q00341 3.32453644 Q00341 1.583497e-03 TRUE
Q13123 3.29492808 Q13123 1.583497e-03 TRUE
Q92522 3.04012137 Q92522 1.962530e-03 TRUE
Q14980 2.94105844 Q14980 2.079426e-03 TRUE
Q14694 2.85112708 Q14694 2.186483e-03 TRUE
Q2TAY7 2.77329003 Q2TAY7 2.274487e-03 TRUE
Q9NR30 2.71003141 Q9NR30 2.334717e-03 TRUE
O60427 2.56962788 O60427 2.536747e-03 TRUE
Q9P258 2.52387666 Q9P258 2.536747e-03 TRUE
Q9Y6M5 2.48409864 Q9Y6M5 2.536747e-03 TRUE
Q9BVP2 2.47416318 Q9BVP2 2.536747e-03 TRUE
Q9P0V3 2.45901842 Q9P0V3 2.536747e-03 TRUE
Q6P5R6 2.34977722 Q6P5R6 2.745317e-03 TRUE
Q92934 2.30246324 Q92934 2.769685e-03 TRUE
Q86XP3 2.28235699 Q86XP3 2.769685e-03 TRUE
O95864 2.21306382 O95864 2.814132e-03 TRUE
Q9NZB2 2.18719870 Q9NZB2 2.814132e-03 TRUE
Q9UQE7 2.18446927 Q9UQE7 2.814132e-03 TRUE
Q6P1J9 1.99688564 Q6P1J9 3.308364e-03 TRUE
P16989 1.91604606 P16989 3.497093e-03 TRUE
Q9BZK7 1.83695990 Q9BZK7 3.692164e-03 TRUE
P08865 1.78898876 P08865 3.780986e-03 TRUE
P26640 1.72526854 P26640 3.935361e-03 TRUE
Q96T58 1.68685180 Q96T58 3.936254e-03 TRUE
Q13151 1.67374468 Q13151 3.936254e-03 TRUE
Q9Y2X3 1.65737116 Q9Y2X3 3.936254e-03 TRUE
Q13451 1.59188333 Q13451 4.112153e-03 TRUE
Q9UKA9 1.53975167 Q9UKA9 4.240939e-03 TRUE
P23434 1.49773330 P23434 4.331749e-03 TRUE
Q9Y333 1.39052408 Q9Y333 4.722616e-03 TRUE
Q53EP0 1.28776035 Q53EP0 5.127610e-03 TRUE
P62906 1.22051338 P62906 5.163545e-03 TRUE
P49711 1.21009707 P49711 5.163545e-03 TRUE
P42285 1.20917043 P42285 5.163545e-03 TRUE
Q16718 1.20465092 Q16718 5.163545e-03 TRUE
P62854 1.12686153 P62854 5.447631e-03 TRUE
Q9BQ39 1.10772508 Q9BQ39 5.447631e-03 TRUE
P62750 1.09710225 P62750 5.447631e-03 TRUE
Q9H2P0 1.03826658 Q9H2P0 5.600247e-03 TRUE
Q49A26 1.03062429 Q49A26 5.600247e-03 TRUE
Q9UQB8 1.01834049 Q9UQB8 5.600247e-03 TRUE
Q96L96 0.94829592 Q96L96 5.905794e-03 TRUE
P62753 0.88507921 P62753 6.187460e-03 TRUE
P16403 0.77784969 P16403 6.650491e-03 TRUE
P62273 0.77012769 P62273 6.650491e-03 TRUE
Q99536 0.75619104 Q99536 6.650491e-03 TRUE
Q06136 0.74993066 Q06136 6.650491e-03 TRUE
Q9UQ35 0.69915601 Q9UQ35 6.655352e-03 TRUE
Q96RU2 0.69591532 Q96RU2 6.655352e-03 TRUE
P61254 0.68926951 P61254 6.655352e-03 TRUE
Q14728 0.67697163 Q14728 6.655352e-03 TRUE
Q9H1E3 0.67640450 Q9H1E3 6.655352e-03 TRUE
Q86U42 0.64251694 Q86U42 6.689712e-03 TRUE
P61313 0.62262994 P61313 6.689712e-03 TRUE
Q01780 0.61237014 Q01780 6.689712e-03 TRUE
P46782 0.60769103 P46782 6.689712e-03 TRUE
Q9HCM4 0.58420148 Q9HCM4 6.689712e-03 TRUE
P30876 0.57809873 P30876 6.689712e-03 TRUE
P39880 0.57080739 P39880 6.689712e-03 TRUE
Q9NQT5 0.56458543 Q9NQT5 6.689712e-03 TRUE
P62280 0.54023271 P62280 6.768010e-03 TRUE
P62701 0.52350618 P62701 6.796854e-03 TRUE
Q92747 0.45129299 Q92747 7.145565e-03 TRUE
P36578 0.44844527 P36578 7.145565e-03 TRUE
P62888 0.43322923 P62888 7.168392e-03 TRUE
Q5QJ74 0.40332925 Q5QJ74 7.267940e-03 TRUE
O75787 0.39570237 O75787 7.267940e-03 TRUE
P49207 0.35515105 P49207 7.478794e-03 TRUE
Q9P0M6 0.31904160 Q9P0M6 7.581754e-03 TRUE
Q6Y7W6 0.31852563 Q6Y7W6 7.581754e-03 TRUE
Q7Z739 0.30701565 Q7Z739 7.584092e-03 TRUE
Q8NC51 0.28873536 Q8NC51 7.638198e-03 TRUE
P18621 0.25873195 P18621 7.727127e-03 TRUE
O00461 0.25520586 O00461 7.727127e-03 TRUE
P46783 0.24154596 P46783 7.749522e-03 TRUE
P19338 0.22056090 P19338 7.829207e-03 TRUE
P53396 0.18985383 P53396 7.986778e-03 TRUE
Q99459 0.17312946 Q99459 8.036761e-03 TRUE
Q9Y5S2 0.14548965 Q9Y5S2 8.175425e-03 TRUE
Q9Y2I6 0.08497617 Q9Y2I6 8.591324e-03 TRUE
O60292 0.03814180 O60292 8.802806e-03 TRUE
P61513 0.03568548 P61513 8.802806e-03 TRUE
Q13509 0.03032847 Q13509 8.802806e-03 TRUE
Q9NVP1 -0.03024043 Q9NVP1 9.254525e-03 TRUE
P62263 -0.04153371 P62263 9.268987e-03 TRUE
P16220 -0.09251412 P16220 9.654642e-03 TRUE
Q9UKU7 -0.14010475 Q9UKU7 9.934553e-03 TRUE
P34932 -0.14048551 P34932 9.934553e-03 TRUE
P83731 -0.15966101 P83731 1.003117e-02 TRUE
P62249 -0.17003751 P62249 1.004212e-02 TRUE
P25398 -0.21961283 P25398 1.018428e-02 TRUE
Q12983 -0.21984771 Q12983 1.018428e-02 TRUE
P07996 -0.22641025 P07996 1.018428e-02 TRUE
Q14966 -0.24450725 Q14966 1.018428e-02 TRUE
P17302 -0.25078521 P17302 1.018428e-02 TRUE
Q9UBG0 -0.25549731 Q9UBG0 1.018428e-02 TRUE
P55769 -0.25870623 P55769 1.018428e-02 TRUE
P21453 -0.25991496 P21453 1.018428e-02 TRUE
P15529 -0.26412804 P15529 1.018428e-02 TRUE
P83881 -0.27905650 P83881 1.024904e-02 TRUE
Q06830 -0.29861235 Q06830 1.034630e-02 TRUE
Q9NUP9 -0.30542402 Q9NUP9 1.034630e-02 TRUE
P08708 -0.34577285 P08708 1.062306e-02 TRUE
P62269 -0.35150638 P62269 1.062306e-02 TRUE
O00541 -0.36397734 O00541 1.062306e-02 TRUE
P62910 -0.36497400 P62910 1.062306e-02 TRUE
P50914 -0.39014678 P50914 1.080401e-02 TRUE
Q9NYV4 -0.41981442 Q9NYV4 1.103747e-02 TRUE
P61353 -0.44838805 P61353 1.126451e-02 TRUE
P54764 -0.46351780 P54764 1.130934e-02 TRUE
P62841 -0.46804190 P62841 1.130934e-02 TRUE
P61247 -0.48103491 P61247 1.136822e-02 TRUE
P62857 -0.50754989 P62857 1.154842e-02 TRUE
P29558 -0.51227167 P29558 1.154842e-02 TRUE
Q99873 -0.52069319 Q99873 1.155835e-02 TRUE
P62424 -0.53406769 P62424 1.157285e-02 TRUE
P18077 -0.53845274 P18077 1.157285e-02 TRUE
Q9H307 -0.54781049 Q9H307 1.157285e-02 TRUE
P06748 -0.55161334 P06748 1.157285e-02 TRUE
Q8IWC1 -0.56802683 Q8IWC1 1.163980e-02 TRUE
Q9NPL8 -0.57919241 Q9NPL8 1.163980e-02 TRUE
Q92784 -0.58494714 Q92784 1.163980e-02 TRUE
Q9H2K0 -0.58627706 Q9H2K0 1.163980e-02 TRUE
O00571 -0.59954613 O00571 1.171102e-02 TRUE
Q9BYV2 -0.61439895 Q9BYV2 1.180163e-02 TRUE
P46778 -0.65633037 P46778 1.221497e-02 TRUE
Q9GZS1 -0.66383870 Q9GZS1 1.222192e-02 TRUE
P19320 -0.68483532 P19320 1.239299e-02 TRUE
P05387 -0.72250756 P05387 1.275284e-02 TRUE
P32969 -0.72752575 P32969 1.275284e-02 TRUE
P82979 -0.73489725 P82979 1.276069e-02 TRUE
P60510 -0.77743645 P60510 1.318072e-02 TRUE
Q71RC2 -0.78462156 Q71RC2 1.318072e-02 TRUE
P24928 -0.78955110 P24928 1.318072e-02 TRUE
Q13084 -0.79777547 Q13084 1.318072e-02 TRUE
Q6P5Q4 -0.80085227 Q6P5Q4 1.318072e-02 TRUE
P10412 -0.82425335 P10412 1.340215e-02 TRUE
O43660 -0.83878393 O43660 1.350931e-02 TRUE
Q9H832 -0.84795251 Q9H832 1.354613e-02 TRUE
P62851 -0.85472467 P62851 1.355157e-02 TRUE
Q9GZS3 -0.88312448 Q9GZS3 1.384947e-02 TRUE
P62847 -0.91823737 P62847 1.423367e-02 TRUE
Q9BYN8 -0.92343378 Q9BYN8 1.423367e-02 TRUE
Q9Y3Y2 -0.93181406 Q9Y3Y2 1.426415e-02 TRUE
P11940 -0.98474375 P11940 1.493664e-02 TRUE
Q9H0S4 -0.99958143 Q9H0S4 1.499412e-02 TRUE
P62899 -1.00087084 P62899 1.499412e-02 TRUE
Q16658 -1.01548568 Q16658 1.505218e-02 TRUE
Q9BXB1 -1.01687608 Q9BXB1 1.505218e-02 TRUE
Q13310 -1.03821622 Q13310 1.522747e-02 TRUE
Q68CP9 -1.05079845 Q68CP9 1.522747e-02 TRUE
Q9NR56 -1.05233625 Q9NR56 1.522747e-02 TRUE
Q5BKY1 -1.05236645 Q5BKY1 1.522747e-02 TRUE
O75155 -1.06793384 O75155 1.526053e-02 TRUE
Q12972 -1.07132729 Q12972 1.526053e-02 TRUE
P62917 -1.07201447 P62917 1.526053e-02 TRUE
Q9Y5H0 -1.13769730 Q9Y5H0 1.606233e-02 TRUE
Q15758 -1.14270654 Q15758 1.606233e-02 TRUE
Q9UJV9 -1.14728461 Q9UJV9 1.606233e-02 TRUE
Q9H0A0 -1.14914015 Q9H0A0 1.606233e-02 TRUE
Q9H7H0 -1.15239640 Q9H7H0 1.606233e-02 TRUE
Q9Y3U8 -1.16800161 Q9Y3U8 1.622168e-02 TRUE
P39019 -1.17534690 P39019 1.625027e-02 TRUE
P63244 -1.18349685 P63244 1.629232e-02 TRUE
Q12888 -1.22658111 Q12888 1.676501e-02 TRUE
Q15024 -1.23590553 Q15024 1.676501e-02 TRUE
P25101 -1.23602701 P25101 1.676501e-02 TRUE
Q9P013 -1.24837454 Q9P013 1.676501e-02 TRUE
Q9UNK0 -1.24899506 Q9UNK0 1.676501e-02 TRUE
P46781 -1.25484823 P46781 1.676501e-02 TRUE
P98155 -1.25554306 P98155 1.676501e-02 TRUE
P46776 -1.25724280 P46776 1.676501e-02 TRUE
Q9NY33 -1.26094565 Q9NY33 1.676501e-02 TRUE
Q9BR76 -1.26816294 Q9BR76 1.679771e-02 TRUE
Q99766 -1.29191711 Q99766 1.706713e-02 TRUE
Q9BQ95 -1.29470089 Q9BQ95 1.706713e-02 TRUE
P29401 -1.31777497 P29401 1.737131e-02 TRUE
P78396 -1.35103389 P78396 1.785992e-02 TRUE
Q9Y224 -1.36839000 Q9Y224 1.807701e-02 TRUE
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O00746 -6.68004520 O00746 4.697450e-01 FALSE
Q15120 -6.68005973 Q15120 4.697450e-01 FALSE
P49754 -6.68032439 P49754 4.702154e-01 FALSE
O95573 -6.68056801 O95573 4.706416e-01 FALSE
Q8N1G4 -6.68076587 Q8N1G4 4.707935e-01 FALSE
Q9H9S3 -6.68078062 Q9H9S3 4.707935e-01 FALSE
P26678 -6.68084373 P26678 4.707935e-01 FALSE
Q15392 -6.68091961 Q15392 4.707935e-01 FALSE
P13010 -6.68094368 P13010 4.707935e-01 FALSE
Q00587 -6.68114155 Q00587 4.710584e-01 FALSE
P05089 -6.68125589 P05089 4.710584e-01 FALSE
Q09666 -6.68127671 Q09666 4.710584e-01 FALSE
Q86SQ0 -6.68129963 Q86SQ0 4.710584e-01 FALSE
P50416 -6.68137121 P50416 4.710839e-01 FALSE
Q0VGL1 -6.68169962 Q0VGL1 4.717404e-01 FALSE
O75475 -6.68186049 O75475 4.719897e-01 FALSE
P01023 -6.68200959 P01023 4.722121e-01 FALSE
Q9ULV4 -6.68223283 Q9ULV4 4.726143e-01 FALSE
P35270 -6.68228840 P35270 4.726143e-01 FALSE
P02545 -6.68261232 P02545 4.732885e-01 FALSE
P61421 -6.68287321 P61421 4.734869e-01 FALSE
P20340 -6.68292993 P20340 4.734869e-01 FALSE
Q9BQA9 -6.68296989 Q9BQA9 4.734869e-01 FALSE
P25789 -6.68297394 P25789 4.734869e-01 FALSE
Q9BXW7 -6.68297834 Q9BXW7 4.734869e-01 FALSE
Q9UKE5 -6.68311695 Q9UKE5 4.735494e-01 FALSE
O94973 -6.68313760 O94973 4.735494e-01 FALSE
Q96MW7 -6.68321332 Q96MW7 4.735494e-01 FALSE
P57105 -6.68323042 P57105 4.735494e-01 FALSE
P61009 -6.68335569 P61009 4.737300e-01 FALSE
Q9H2H9 -6.68357186 Q9H2H9 4.741538e-01 FALSE
Q9H6E4 -6.68367074 Q9H6E4 4.742687e-01 FALSE
Q8N9W4 -6.68376431 Q8N9W4 4.742963e-01 FALSE
Q8NE71 -6.68379203 Q8NE71 4.742963e-01 FALSE
Q9NZN4 -6.68402149 Q9NZN4 4.747673e-01 FALSE
Q8TEM1 -6.68409525 Q8TEM1 4.748191e-01 FALSE
O43819 -6.68424157 O43819 4.749071e-01 FALSE
Q12846 -6.68426216 Q12846 4.749071e-01 FALSE
P07355 -6.68433946 P07355 4.749071e-01 FALSE
Q6P0N0 -6.68434442 Q6P0N0 4.749071e-01 FALSE
Q6P1M3 -6.68441100 Q6P1M3 4.749422e-01 FALSE
Q13177 -6.68486851 Q13177 4.760724e-01 FALSE
Q9Y4G6 -6.68497857 Q9Y4G6 4.762357e-01 FALSE
Q5SV97 -6.68525065 Q5SV97 4.768662e-01 FALSE
O75907 -6.68530421 O75907 4.768720e-01 FALSE
P47897 -6.68538768 P47897 4.769650e-01 FALSE
P63000 -6.68545309 P63000 4.770064e-01 FALSE
Q96G01 -6.68550981 Q96G01 4.770218e-01 FALSE
Q9NTK5 -6.68556914 Q9NTK5 4.770218e-01 FALSE
Q86UP2 -6.68561091 Q86UP2 4.770218e-01 FALSE
O95479 -6.68569411 O95479 4.771181e-01 FALSE
P30084 -6.68596308 P30084 4.777694e-01 FALSE
Q9NRV9 -6.68611156 Q9NRV9 4.780675e-01 FALSE
P62805 -6.68625434 P62805 4.781830e-01 FALSE
P10301 -6.68627848 P10301 4.781830e-01 FALSE
O43684 -6.68629656 O43684 4.781830e-01 FALSE
Q14155 -6.68650427 Q14155 4.786728e-01 FALSE
Q8TD19 -6.68707051 Q8TD19 4.802351e-01 FALSE
P69905 -6.68710888 P69905 4.802351e-01 FALSE
O14958 -6.68717221 O14958 4.802351e-01 FALSE
Q15560 -6.68721096 Q15560 4.802351e-01 FALSE
Q9Y6N5 -6.68723296 Q9Y6N5 4.802351e-01 FALSE
O76003 -6.68732615 O76003 4.803891e-01 FALSE
Q9BR39 -6.68740344 Q9BR39 4.804928e-01 FALSE
Q5TAQ9 -6.68754959 Q5TAQ9 4.808062e-01 FALSE
Q96E39 -6.68758877 Q96E39 4.808062e-01 FALSE
P61204 -6.68767790 P61204 4.809540e-01 FALSE
Q14934 -6.68775350 Q14934 4.810583e-01 FALSE
Q15005 -6.68785432 Q15005 4.811753e-01 FALSE
Q9C0D9 -6.68787655 Q9C0D9 4.811753e-01 FALSE
Q9Y320 -6.68805428 Q9Y320 4.816329e-01 FALSE
P11498 -6.68820123 P11498 4.817238e-01 FALSE
O60763 -6.68821359 O60763 4.817238e-01 FALSE
P33993 -6.68828606 P33993 4.817238e-01 FALSE
Q86VU5 -6.68832651 Q86VU5 4.817238e-01 FALSE
P35998 -6.68832671 P35998 4.817238e-01 FALSE
O75369 -6.68833841 O75369 4.817238e-01 FALSE
Q9P2R3 -6.68838049 Q9P2R3 4.817238e-01 FALSE
P20618 -6.68842760 P20618 4.817411e-01 FALSE
Q5XKP0 -6.68857814 Q5XKP0 4.821273e-01 FALSE
P51809 -6.68874855 P51809 4.825924e-01 FALSE
O15228 -6.68882366 O15228 4.827168e-01 FALSE
P46939 -6.68892248 P46939 4.829303e-01 FALSE
P04062 -6.68910404 P04062 4.832345e-01 FALSE
P09382 -6.68917174 P09382 4.832345e-01 FALSE
P27694 -6.68917250 P27694 4.832345e-01 FALSE
O00462 -6.68918882 O00462 4.832345e-01 FALSE
P22307 -6.68920385 P22307 4.832345e-01 FALSE
Q9NZM3 -6.68933782 Q9NZM3 4.833650e-01 FALSE
P34931 -6.68935613 P34931 4.833650e-01 FALSE
P16219 -6.68938626 P16219 4.833650e-01 FALSE
P00734 -6.68945851 P00734 4.833650e-01 FALSE
Q9BS26 -6.68948668 Q9BS26 4.833650e-01 FALSE
Q14974 -6.68951542 Q14974 4.833650e-01 FALSE
Q9UN42 -6.68956460 Q9UN42 4.833650e-01 FALSE
P50402 -6.68958473 P50402 4.833650e-01 FALSE
P01112 -6.68958627 P01112 4.833650e-01 FALSE
Q9NUM4 -6.68963639 Q9NUM4 4.833989e-01 FALSE
Q9BWM7 -6.68967489 Q9BWM7 4.833989e-01 FALSE
Q969M1 -6.68970816 Q969M1 4.833989e-01 FALSE
P05166 -6.68977902 P05166 4.835319e-01 FALSE
Q8N2H3 -6.68985476 Q8N2H3 4.836821e-01 FALSE
P46060 -6.68989407 P46060 4.836821e-01 FALSE
P24043 -6.68998443 P24043 4.836821e-01 FALSE
P13051 -6.69000860 P13051 4.836821e-01 FALSE
Q02252 -6.69001724 Q02252 4.836821e-01 FALSE
Q8NFH5 -6.69009858 Q8NFH5 4.836821e-01 FALSE
Q9UBM7 -6.69010847 Q9UBM7 4.836821e-01 FALSE
Q9NVT9 -6.69013918 Q9NVT9 4.836821e-01 FALSE
Q15691 -6.69014454 Q15691 4.836821e-01 FALSE
Q15070 -6.69033023 Q15070 4.842837e-01 FALSE
P06865 -6.69035875 P06865 4.842837e-01 FALSE
Q4G176 -6.69061271 Q4G176 4.849408e-01 FALSE
P00761 -6.69068284 P00761 4.849408e-01 FALSE
O00425 -6.69076150 O00425 4.849408e-01 FALSE
Q02127 -6.69076719 Q02127 4.849408e-01 FALSE
P08F94 -6.69078448 P08F94 4.849408e-01 FALSE
Q14677 -6.69080079 Q14677 4.849408e-01 FALSE
P08651 -6.69082557 P08651 4.849408e-01 FALSE
P28066 -6.69084298 P28066 4.849408e-01 FALSE
Q14249 -6.69086075 Q14249 4.849408e-01 FALSE
Q9UDY2 -6.69086532 Q9UDY2 4.849408e-01 FALSE
Q99755 -6.69088038 Q99755 4.849408e-01 FALSE
Q9Y2P4 -6.69097385 Q9Y2P4 4.852189e-01 FALSE
P63165 -6.69109324 P63165 4.854724e-01 FALSE
Q9NYK1 -6.69110624 Q9NYK1 4.854724e-01 FALSE
Q9H019 -6.69112428 Q9H019 4.854724e-01 FALSE
Q8TDY8 -6.69116696 Q8TDY8 4.855224e-01 FALSE
Q9NYF8 -6.69122770 Q9NYF8 4.855224e-01 FALSE
Q9HD23 -6.69122883 Q9HD23 4.855224e-01 FALSE
P48723 -6.69127780 P48723 4.856084e-01 FALSE
Q99594 -6.69133784 Q99594 4.856720e-01 FALSE
Q9Y2U8 -6.69135234 Q9Y2U8 4.856720e-01 FALSE
O75027 -6.69150937 O75027 4.861262e-01 FALSE
Q5SSJ5 -6.69153115 Q5SSJ5 4.861262e-01 FALSE
O75400 -6.69155681 O75400 4.861262e-01 FALSE
P31327 -6.69157278 P31327 4.861262e-01 FALSE
Q9Y2A7 -6.69161165 Q9Y2A7 4.861262e-01 FALSE
Q9UID3 -6.69164571 Q9UID3 4.861262e-01 FALSE
P14543 -6.69167506 P14543 4.861262e-01 FALSE
P17152 -6.69168105 P17152 4.861262e-01 FALSE
Q13620 -6.69191089 Q13620 4.870847e-01 FALSE
P29992 -6.69192112 P29992 4.870847e-01 FALSE
Q5T2T1 -6.69199239 Q5T2T1 4.873202e-01 FALSE
P62140 -6.69211127 P62140 4.876382e-01 FALSE
Q969V3 -6.69212247 Q969V3 4.876382e-01 FALSE
O75063 -6.69213893 O75063 4.876382e-01 FALSE
O43765 -6.69215745 O43765 4.876382e-01 FALSE
Q8N2F6 -6.69231021 Q8N2F6 4.883600e-01 FALSE
Q8WVX9 -6.69253481 Q8WVX9 4.895475e-01 FALSE
Q14139 -6.69266565 Q14139 4.902129e-01 FALSE
P82933 -6.69277252 P82933 4.906662e-01 FALSE
Q01813 -6.69278228 Q01813 4.906662e-01 FALSE
Q9BX66 -6.69283060 Q9BX66 4.907684e-01 FALSE
P60891 -6.69285752 P60891 4.907684e-01 FALSE
P11021 -6.69287675 P11021 4.907684e-01 FALSE
Q9NSV4 -6.69288702 Q9NSV4 4.907684e-01 FALSE
P02786 -6.69294390 P02786 4.910069e-01 FALSE
Q15075 -6.69298100 Q15075 4.911148e-01 FALSE
P50440 -6.69300586 P50440 4.911399e-01 FALSE
Q96ER9 -6.69303097 Q96ER9 4.911683e-01 FALSE
Q9H0V9 -6.69306287 Q9H0V9 4.912465e-01 FALSE
Q96SJ8 -6.69313652 Q96SJ8 4.916307e-01 FALSE
Q9UDR5 -6.69324836 Q9UDR5 4.922211e-01 FALSE
Q99436 -6.69329334 Q99436 4.922211e-01 FALSE
P07910 -6.69330329 P07910 4.922211e-01 FALSE
P43121 -6.69330548 P43121 4.922211e-01 FALSE
Q969Z3 -6.69332901 Q969Z3 4.922211e-01 FALSE
Q9P291 -6.69333111 Q9P291 4.922211e-01 FALSE
Q96I51 -6.69335664 Q96I51 4.922759e-01 FALSE
P12270 -6.69338531 P12270 4.923043e-01 FALSE
P62993 -6.69341311 P62993 4.923043e-01 FALSE
O43852 -6.69341501 O43852 4.923043e-01 FALSE
O00186 -6.69354640 O00186 4.932681e-01 FALSE
P61020 -6.69357300 P61020 4.933542e-01 FALSE
Q9UJW0 -6.69365387 Q9UJW0 4.939398e-01 FALSE
P50213 -6.69367977 P50213 4.940340e-01 FALSE
P13861 -6.69370506 P13861 4.941149e-01 FALSE
Q8NDZ4 -6.69373159 Q8NDZ4 4.941149e-01 FALSE
P35659 -6.69374169 P35659 4.941149e-01 FALSE
P56747 -6.69375129 P56747 4.941149e-01 FALSE
O95861 -6.69376458 O95861 4.941149e-01 FALSE
Q68D91 -6.69382280 Q68D91 4.945177e-01 FALSE
Q96D53 -6.69384693 Q96D53 4.945177e-01 FALSE
Q9GZP0 -6.69384718 Q9GZP0 4.945177e-01 FALSE
Q9UBX3 -6.69386800 Q9UBX3 4.945916e-01 FALSE
Q6Y288 -6.69388580 Q6Y288 4.946141e-01 FALSE
Q58EX2 -6.69391048 Q58EX2 4.946141e-01 FALSE
Q9P035 -6.69391067 Q9P035 4.946141e-01 FALSE
Q92614 -6.69393105 Q92614 4.946949e-01 FALSE
O75376 -6.69395546 O75376 4.948265e-01 FALSE
O43615 -6.69399068 O43615 4.949840e-01 FALSE
O43169 -6.69399391 O43169 4.949840e-01 FALSE
Q6UW68 -6.69403286 Q6UW68 4.951918e-01 FALSE
P35968 -6.69403495 P35968 4.951918e-01 FALSE
Q9GZY4 -6.69404913 Q9GZY4 4.952231e-01 FALSE
Q8IZQ5 -6.69407310 Q8IZQ5 4.953303e-01 FALSE
O60841 -6.69408020 O60841 4.953303e-01 FALSE
P28288 -6.69409240 P28288 4.953448e-01 FALSE
O75417 -6.69415329 O75417 4.960466e-01 FALSE
Q15067 -6.69417614 Q15067 4.962373e-01 FALSE
P26368 -6.69421171 P26368 4.964556e-01 FALSE
P23919 -6.69421245 P23919 4.964556e-01 FALSE
Q155Q3 -6.69422554 Q155Q3 4.964556e-01 FALSE
Q13232 -6.69422754 Q13232 4.964556e-01 FALSE
Q6FI81 -6.69423719 Q6FI81 4.964684e-01 FALSE
O00505 -6.69428425 O00505 4.971514e-01 FALSE
Q15008 -6.69429821 Q15008 4.972680e-01 FALSE
O00743 -6.69430938 O00743 4.973387e-01 FALSE
Q32P44 -6.69435312 Q32P44 4.981205e-01 FALSE
P78417 -6.69436435 P78417 4.982347e-01 FALSE
P14621 -6.69437287 P14621 4.982936e-01 FALSE
Q9BYD1 -6.69438001 Q9BYD1 4.983248e-01 FALSE
P61586 -6.69439056 P61586 4.984529e-01 FALSE
Q14566 -6.69439736 Q14566 4.984907e-01 FALSE
P10915 -6.69440748 P10915 4.986324e-01 FALSE
Q9BXS5 -6.69443460 Q9BXS5 4.993656e-01 FALSE
Q6P1M0 -6.69444145 Q6P1M0 4.993836e-01 FALSE
Q9C0D5 -6.69444293 Q9C0D5 4.993836e-01 FALSE
Q15185 -6.69444902 Q15185 4.993849e-01 FALSE
P51153 -6.69445018 P51153 4.993849e-01 FALSE
P29144 -6.69445665 P29144 4.995269e-01 FALSE
P09543 -6.69447856 P09543 5.007025e-01 FALSE
Q9BZF1 -6.69448357 Q9BZF1 5.010516e-01 FALSE
Q92538 -6.69448566 Q92538 5.011896e-01 FALSE
Q96N64 -6.69448651 Q96N64 5.011896e-01 FALSE
Q52LJ0 -6.69448746 Q52LJ0 5.011896e-01 FALSE
P54753 -6.69448773 P54753 5.011896e-01 FALSE# 2. Do the volcano plot
ggplot(toptable_Threshold_0.05)+
geom_point(mapping = aes(x = logFC, y = -log10(adj.P.Val), color = threshold_P))+
xlab("log2FC")+
ylab("-log10 adjusted p-value")+
ylim(0, 5)+
xlim(-5, 5)+
theme(legend.position = "none",
plot.title = element_text(size = rel(1.5), hjust = 0.5),
axis.title = element_text(size = rel(1.25)))+
theme_bw()
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Volcano with adj. Q
# 1. Create a column to threshold adjusted P-values/q-values
toptable_Threshold_0.05 <- toptable_Dupcor %>% mutate(threshold_Q = adj_q_values < 0.05)
toptable_Threshold_0.05 logFC AveExpr t P.Value adj.P.Val
Q15327 -3.5538167761 23.99047 -16.743392583 2.054348e-08 6.951913e-05
O76021 -2.1410928975 24.25375 -13.552273075 1.444049e-07 2.443330e-04
Q96LW7 -1.6342957224 19.97143 -12.658156240 2.690260e-07 3.034614e-04
Q969Q1 -4.3423803749 20.84232 -11.920968346 4.632261e-07 3.918893e-04
P19388 -1.1658966201 20.44496 -11.622278836 5.822611e-07 3.940743e-04
Q96GQ7 -1.7622803092 20.67219 -10.833687964 1.092754e-06 6.163133e-04
O43159 -2.1096892264 20.56152 -10.318875713 1.684397e-06 8.142856e-04
Q6EMK4 2.3724491682 21.06129 9.656663573 3.021583e-06 1.278129e-03
P17844 -1.1425406345 25.94182 -9.304080076 4.181540e-06 1.572259e-03
Q96PU8 -2.1455298252 21.20691 -8.951039111 5.848963e-06 1.881965e-03
Q14498 -0.8019789647 23.53525 -8.890645629 6.201192e-06 1.881965e-03
P67809 -1.1045436713 26.08944 -8.774842757 6.943236e-06 1.881965e-03
Q9BQG0 -2.2554253126 23.65243 -8.733704263 7.229772e-06 1.881965e-03
P17480 0.7861550384 24.19823 8.375813153 1.034545e-05 2.500644e-03
Q13641 1.3614453777 21.17736 8.173707956 1.273359e-05 2.711717e-03
P48634 -1.0858313049 20.62697 -8.167089200 1.282136e-05 2.711717e-03
Q92841 -0.7539368895 27.56259 -8.106875865 1.365082e-05 2.717316e-03
Q4G0J3 -0.7752299178 23.21486 -7.930348626 1.643911e-05 3.007123e-03
P78347 -0.7435322555 26.03868 -7.905231639 1.688397e-05 3.007123e-03
Q02818 -2.3955560537 22.73869 -7.799179727 1.891244e-05 3.156765e-03
Q00341 -0.9058215272 24.57254 -7.751362535 1.991267e-05 3.156765e-03
Q13123 -1.1338838135 22.25040 -7.723467328 2.052270e-05 3.156765e-03
Q92522 -1.6536207267 24.17315 -7.487060032 2.659124e-05 3.912381e-03
Q14980 -1.2192370415 24.62561 -7.396873728 2.940013e-05 4.145419e-03
Q14694 -0.7674689571 22.72482 -7.315811636 3.220183e-05 4.358840e-03
Q2TAY7 -0.7632109180 23.97921 -7.246263013 3.483785e-05 4.534280e-03
Q9NR30 -1.0206069551 23.97933 -7.190152266 3.713578e-05 4.654352e-03
O60427 -1.2083869980 21.17097 -7.066908229 4.278320e-05 5.057106e-03
Q9P258 1.7059490390 21.25515 7.027127742 4.480026e-05 5.057106e-03
Q9Y6M5 1.1382005458 23.05230 6.992690129 4.662999e-05 5.057106e-03
Q9BVP2 -1.5081799250 21.49507 -6.984110085 4.709839e-05 5.057106e-03
Q9P0V3 -1.5653815562 20.47551 -6.971047875 4.782133e-05 5.057106e-03
Q6P5R6 -1.8797159229 20.65233 -6.877412686 5.337046e-05 5.472898e-03
Q92934 -1.2351650877 21.23559 -6.837172761 5.596677e-05 5.521477e-03
Q86XP3 -0.7285835498 23.65238 -6.820129601 5.710747e-05 5.521477e-03
O95864 -2.6174073619 19.59627 -6.761650756 6.121744e-05 5.610083e-03
Q9NZB2 -1.0158315089 23.24048 -6.739923968 6.282530e-05 5.610083e-03
Q9UQE7 -1.4794349461 20.76312 -6.737634433 6.299739e-05 5.610083e-03
Q6P1J9 -0.7979336434 22.49594 -6.581727353 7.601030e-05 6.595355e-03
P16989 -2.7782295557 21.60829 -6.515400547 8.240654e-05 6.971593e-03
Q9BZK7 -0.6448869669 22.87123 -6.451002969 8.917833e-05 7.360475e-03
P08865 -0.6951266140 26.40427 -6.412174570 9.355111e-05 7.537546e-03
P26640 0.5742911993 24.75172 6.360867386 9.968907e-05 7.845298e-03
Q96T58 1.2393881736 22.45091 6.330081073 1.035805e-04 7.847079e-03
Q13151 -0.7134418171 25.34094 -6.319602357 1.049423e-04 7.847079e-03
Q9Y2X3 0.6514755296 25.29422 6.306530078 1.066683e-04 7.847079e-03
Q13451 0.7026843452 19.60808 6.254442541 1.138575e-04 8.197740e-03
Q9UKA9 -0.7576536433 24.34593 -6.213200990 1.199217e-04 8.454480e-03
P23434 0.9639278116 22.27141 6.180102278 1.250414e-04 8.635514e-03
Q9Y333 -1.6242843304 20.77853 -6.096218482 1.391064e-04 9.414723e-03
Q53EP0 -1.4507298032 22.03019 -6.016564592 1.540564e-04 1.022209e-02
P62906 -0.9477995132 25.76636 -5.964830968 1.646908e-04 1.029373e-02
P49711 -0.7460068993 21.19290 -5.956844911 1.664019e-04 1.029373e-02
P42285 -0.9617635928 22.20386 -5.956134822 1.665550e-04 1.029373e-02
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O60763 -0.0139831853 24.73159 -0.107441446 9.166556e-01 9.603356e-01
P33993 0.0296264221 22.95476 0.106818749 9.171366e-01 9.603356e-01
Q86VU5 -0.0246204336 23.37687 -0.106469690 9.174062e-01 9.603356e-01
P35998 -0.0100998261 25.38112 -0.106467932 9.174076e-01 9.603356e-01
O75369 -0.0491792455 25.49266 -0.106366787 9.174857e-01 9.603356e-01
Q9P2R3 -0.0160556032 23.35655 -0.106001999 9.177675e-01 9.603356e-01
P20618 0.0094208407 24.82056 0.105592157 9.180842e-01 9.603700e-01
Q5XKP0 0.0182047101 25.41729 0.104271843 9.191043e-01 9.611400e-01
P51809 0.0184585233 23.30146 0.102756756 9.202752e-01 9.620671e-01
O15228 -0.0163471219 23.14290 -0.102081817 9.207968e-01 9.623151e-01
P46939 0.0183565192 25.16419 0.101187000 9.214885e-01 9.627406e-01
P04062 -0.0186540967 23.81559 -0.099522119 9.227755e-01 9.633472e-01
P09382 -0.0307928569 25.49314 -0.098894180 9.232610e-01 9.633472e-01
P27694 0.0277877963 24.86406 0.098887044 9.232665e-01 9.633472e-01
O00462 -0.0097998990 25.08341 -0.098735102 9.233840e-01 9.633472e-01
P22307 -0.0145158437 25.76061 -0.098594857 9.234924e-01 9.633472e-01
Q9NZM3 0.0221290468 23.74942 0.097336464 9.244655e-01 9.636073e-01
P34931 -0.0198052635 24.65605 -0.097163206 9.245995e-01 9.636073e-01
P16219 -0.0142894513 24.99126 -0.096877470 9.248205e-01 9.636073e-01
P00734 -0.0218670313 20.79997 -0.096188763 9.253531e-01 9.636073e-01
Q9BS26 0.0118885102 26.53071 0.095918890 9.255618e-01 9.636073e-01
Q14974 0.0091638057 26.60580 0.095642815 9.257753e-01 9.636073e-01
Q9UN42 0.0529851700 24.44938 0.095168421 9.261423e-01 9.636073e-01
P50402 -0.0092716097 25.43118 -0.094973649 9.262929e-01 9.636073e-01
P01112 0.0135000733 24.14441 0.094958654 9.263045e-01 9.636073e-01
Q9NUM4 0.0223334393 22.01896 0.094471818 9.266811e-01 9.636750e-01
Q9BWM7 0.0217927237 24.70386 0.094096025 9.269718e-01 9.636750e-01
Q969M1 0.0210633620 21.82823 0.093770125 9.272239e-01 9.636750e-01
P05166 0.0107373080 25.22551 0.093072210 9.277638e-01 9.639401e-01
Q8N2H3 0.0407270612 23.71033 0.092320385 9.283455e-01 9.642394e-01
P46060 0.0101036945 22.55457 0.091927779 9.286493e-01 9.642394e-01
P24043 -0.0286933388 22.52164 -0.091018854 9.293526e-01 9.642394e-01
P13051 -0.0239032109 20.23308 -0.090774256 9.295419e-01 9.642394e-01
Q02252 0.0114156845 26.84969 0.090686632 9.296097e-01 9.642394e-01
Q8NFH5 -0.0086793530 20.80922 -0.089857588 9.302513e-01 9.642394e-01
Q9UBM7 0.0265568097 24.51966 0.089756303 9.303297e-01 9.642394e-01
Q9NVT9 -0.0695866795 24.16418 -0.089440953 9.305737e-01 9.642394e-01
Q15691 -0.0244255009 23.41869 -0.089385757 9.306164e-01 9.642394e-01
Q15070 -0.0250575927 24.80790 -0.087453602 9.321120e-01 9.654389e-01
P06865 0.0111440839 24.87987 0.087153035 9.323446e-01 9.654389e-01
Q4G176 -0.0116557149 24.14503 -0.084429697 9.344531e-01 9.667488e-01
P00761 0.0096551066 31.08365 0.083661976 9.350476e-01 9.667488e-01
O00425 -0.0088968604 26.12775 -0.082792556 9.357208e-01 9.667488e-01
Q02127 0.0119945538 22.14724 0.082729316 9.357698e-01 9.667488e-01
P08F94 -0.0186971056 21.20035 -0.082536801 9.359189e-01 9.667488e-01
Q14677 0.0118688959 20.45310 0.082354795 9.360599e-01 9.667488e-01
P08651 -0.0121724593 20.69112 -0.082077547 9.362746e-01 9.667488e-01
P28066 0.0076420581 24.33706 0.081882140 9.364259e-01 9.667488e-01
Q14249 0.0095893912 24.57991 0.081682259 9.365807e-01 9.667488e-01
Q9UDY2 -0.0253243845 20.15616 -0.081630790 9.366206e-01 9.667488e-01
Q99755 0.0418349618 18.76583 0.081460879 9.367522e-01 9.667488e-01
Q9Y2P4 0.0127607804 24.04330 0.080398436 9.375751e-01 9.673031e-01
P63165 0.0123175233 21.71677 0.079020619 9.386425e-01 9.678086e-01
Q9NYK1 -0.0498251988 23.31318 -0.078869131 9.387598e-01 9.678086e-01
Q9H019 -0.0092611101 22.90488 -0.078658462 9.389230e-01 9.678086e-01
Q8TDY8 -0.0426163562 19.12771 -0.078157765 9.393109e-01 9.679082e-01
Q9NYF8 0.0085150296 25.65458 0.077439550 9.398674e-01 9.679082e-01
Q9HD23 0.0119060604 21.38225 0.077426125 9.398778e-01 9.679082e-01
P48723 -0.0102901119 22.73254 -0.076842096 9.403303e-01 9.680796e-01
Q99594 -0.0193135842 20.32437 -0.076120062 9.408898e-01 9.682065e-01
Q9Y2U8 0.0098060997 22.99646 0.075944555 9.410258e-01 9.682065e-01
O75027 -0.0099842542 24.53979 -0.074018291 9.425185e-01 9.691118e-01
Q5SSJ5 0.0073752285 26.66669 0.073747130 9.427287e-01 9.691118e-01
O75400 -0.0124379818 24.09084 -0.073426358 9.429773e-01 9.691118e-01
P31327 0.0136571174 23.68287 0.073226019 9.431326e-01 9.691118e-01
Q9Y2A7 0.0125353448 23.81438 0.072736143 9.435123e-01 9.691118e-01
Q9UID3 0.0295843740 19.75980 0.072304102 9.438472e-01 9.691118e-01
P14543 -0.0167919221 23.69376 -0.071929886 9.441372e-01 9.691118e-01
P17152 -0.0105953273 23.41777 -0.071853200 9.441967e-01 9.691118e-01
Q13620 0.0145089750 23.68199 0.068848276 9.465262e-01 9.710227e-01
P29992 -0.0064416056 25.11985 -0.068711426 9.466323e-01 9.710227e-01
Q5T2T1 0.0097889222 19.07726 0.067750831 9.473772e-01 9.714922e-01
P62140 0.0079203715 26.50835 0.066117357 9.486438e-01 9.721262e-01
Q969V3 -0.0091642882 24.65837 -0.065961302 9.487649e-01 9.721262e-01
O75063 -0.0196776515 20.88879 -0.065731441 9.489431e-01 9.721262e-01
O43765 -0.0198025217 25.84904 -0.065471807 9.491445e-01 9.721262e-01
Q8N2F6 -0.0198511112 22.52100 -0.063289545 9.508370e-01 9.735650e-01
Q8WVX9 0.0060289228 18.79905 0.059937211 9.534375e-01 9.759324e-01
Q14139 -0.0057615311 22.36123 -0.057894924 9.550221e-01 9.772588e-01
P82933 0.0054829992 25.65392 0.056171698 9.563593e-01 9.781625e-01
Q01813 0.0167370873 27.35581 0.056011786 9.564834e-01 9.781625e-01
Q9BX66 0.0143358680 21.78936 0.055212659 9.571035e-01 9.783663e-01
P60891 0.0067843410 25.93807 0.054762504 9.574529e-01 9.783663e-01
P11021 0.0063562359 30.65990 0.054438581 9.577043e-01 9.783663e-01
Q9NSV4 0.0171790228 18.90526 0.054264910 9.578391e-01 9.783663e-01
P02786 0.0070610326 28.18432 0.053292307 9.585939e-01 9.788418e-01
Q15075 0.0050036274 26.59854 0.052648238 9.590938e-01 9.790569e-01
P50440 0.0143064229 23.95149 0.052212300 9.594322e-01 9.791069e-01
Q96ER9 -0.0102512056 22.44630 -0.051768147 9.597770e-01 9.791635e-01
Q9H0V9 -0.0093153054 23.67906 -0.051198399 9.602192e-01 9.793194e-01
Q96SJ8 -0.0156754084 21.16539 -0.049857987 9.612597e-01 9.800853e-01
Q9UDR5 0.0064776062 26.72489 0.047750841 9.628956e-01 9.812624e-01
Q99436 0.0067940073 24.84376 0.046876834 9.635742e-01 9.812624e-01
P07910 0.0061472861 25.80692 0.046681226 9.637261e-01 9.812624e-01
P43121 0.0072381493 25.74715 0.046638044 9.637596e-01 9.812624e-01
Q969Z3 -0.0054001601 25.20349 -0.046171842 9.641216e-01 9.812624e-01
Q9P291 0.0057158178 25.18091 0.046130028 9.641541e-01 9.812624e-01
Q96I51 -0.0099153320 22.36944 -0.045618276 9.645514e-01 9.813716e-01
P12270 -0.0063074599 25.52478 -0.045036686 9.650030e-01 9.814281e-01
P62993 -0.0191703184 21.93934 -0.044465395 9.654466e-01 9.814281e-01
O43852 -0.0066212747 26.73698 -0.044426234 9.654770e-01 9.814281e-01
O00186 -0.0047971737 24.18030 -0.041618048 9.676578e-01 9.833495e-01
P61020 0.0097273667 23.77504 0.041026201 9.681174e-01 9.835213e-01
Q9UJW0 -0.0059093156 21.61949 -0.039172094 9.695575e-01 9.846886e-01
P50213 -0.0051954398 29.24408 -0.038559279 9.700335e-01 9.848765e-01
P13861 -0.0050914180 25.47757 -0.037951567 9.705055e-01 9.850378e-01
Q8NDZ4 -0.0086632938 22.12834 -0.037303220 9.710091e-01 9.850378e-01
P35659 -0.0044616574 24.57097 -0.037053420 9.712032e-01 9.850378e-01
P56747 0.0187623726 22.70278 0.036814390 9.713888e-01 9.850378e-01
O95861 -0.0054869445 21.62864 -0.036481025 9.716478e-01 9.850378e-01
Q68D91 -0.0095284586 21.60360 -0.034982953 9.728115e-01 9.858407e-01
Q96D53 -0.0072857034 21.18247 -0.034343139 9.733086e-01 9.858407e-01
Q9GZP0 0.0175080541 19.10221 0.034336389 9.733138e-01 9.858407e-01
Q9UBX3 -0.0059197351 24.59611 -0.033774291 9.737505e-01 9.859879e-01
Q6Y288 0.0073062541 19.45079 0.033286033 9.741298e-01 9.860329e-01
Q58EX2 0.0102423104 20.21960 0.032597398 9.746648e-01 9.860329e-01
Q9P035 -0.0044522294 24.84269 -0.032591930 9.746690e-01 9.860329e-01
Q92614 -0.0028647118 27.76244 -0.032011880 9.751197e-01 9.861940e-01
O75376 0.0074416599 21.25635 0.031302942 9.756705e-01 9.864562e-01
O43615 0.0037622817 26.76185 0.030250962 9.764878e-01 9.867703e-01
O43169 0.0032027964 25.40996 0.030152532 9.765643e-01 9.867703e-01
Q6UW68 0.0046572920 24.02324 0.028940720 9.775059e-01 9.871844e-01
P35968 0.0047097694 22.81438 0.028874123 9.775576e-01 9.871844e-01
Q9GZY4 -0.0055021156 22.45684 -0.028419001 9.779113e-01 9.872469e-01
Q8IZQ5 0.0066248105 21.22786 0.027632841 9.785221e-01 9.874605e-01
O60841 -0.0035220559 23.29606 -0.027395651 9.787065e-01 9.874605e-01
P28288 -0.0036256509 25.16783 -0.026983209 9.790269e-01 9.874895e-01
O75417 0.0054159815 22.72883 0.024822018 9.807064e-01 9.888887e-01
Q15067 0.0044210791 24.49190 0.023960695 9.813757e-01 9.892688e-01
P26368 -0.0022281622 25.59537 -0.022554523 9.824685e-01 9.897040e-01
P23919 -0.0032968988 23.83964 -0.022524558 9.824918e-01 9.897040e-01
Q155Q3 0.0028108220 19.49408 0.021983738 9.829121e-01 9.897040e-01
Q13232 -0.0035464856 23.30546 -0.021899863 9.829773e-01 9.897040e-01
Q6FI81 0.0039575492 22.46627 0.021490816 9.832952e-01 9.897296e-01
O00505 0.0085658006 21.80293 0.019373553 9.849407e-01 9.910911e-01
Q15008 0.0024531736 24.84515 0.018699420 9.854646e-01 9.913235e-01
O00743 -0.0030229107 20.62747 -0.018142189 9.858977e-01 9.914644e-01
Q32P44 -0.0035448747 20.06958 -0.015770667 9.877410e-01 9.930230e-01
P78417 0.0018041193 23.56780 0.015101749 9.882609e-01 9.932506e-01
P14621 -0.0045005530 20.78173 -0.014573761 9.886713e-01 9.933680e-01
Q9BYD1 0.0015316464 24.46061 0.014116314 9.890268e-01 9.934303e-01
P61586 0.0013072005 26.74816 0.013411483 9.895747e-01 9.936857e-01
Q14566 0.0021581420 23.68538 0.012937085 9.899434e-01 9.937611e-01
P10915 0.0050398203 23.61243 0.012197305 9.905185e-01 9.940434e-01
Q9BXS5 -0.0015175385 22.77994 -0.009945018 9.922692e-01 9.955052e-01
Q6P1M0 -0.0013230822 22.76586 -0.009290689 9.927778e-01 9.955410e-01
Q9C0D5 0.0037181052 19.95329 0.009142181 9.928933e-01 9.955410e-01
Q15185 0.0008048923 24.10663 0.008508503 9.933859e-01 9.955435e-01
P51153 0.0012681861 22.33613 0.008381986 9.934842e-01 9.955435e-01
P29144 0.0012070742 25.09501 0.007639958 9.940610e-01 9.958267e-01
P09543 0.0006074187 25.46963 0.004251034 9.966954e-01 9.981702e-01
Q9BZF1 -0.0006529423 22.69373 -0.002977151 9.976857e-01 9.988664e-01
Q92538 0.0002573516 22.84061 0.002240344 9.982584e-01 9.991413e-01
Q96N64 -0.0002124377 21.72457 -0.001860990 9.985533e-01 9.991413e-01
Q52LJ0 -0.0003543919 23.01653 -0.001309060 9.989824e-01 9.991413e-01
P54753 -0.0002160733 24.88610 -0.001104627 9.991413e-01 9.991413e-01
B Protein adj_q_values threshold_Q
Q15327 9.41678906 Q15327 3.487221e-05 TRUE
O76021 7.85938218 O76021 1.225624e-04 TRUE
Q96LW7 7.32858329 Q96LW7 1.522224e-04 TRUE
Q969Q1 6.85315287 Q969Q1 1.965796e-04 TRUE
P19388 6.64995911 P19388 1.976757e-04 TRUE
Q96GQ7 6.08177746 Q96GQ7 3.091553e-04 TRUE
O43159 5.68418526 O43159 4.084622e-04 TRUE
Q6EMK4 5.13889238 Q6EMK4 6.411357e-04 TRUE
P17844 4.83188794 P17844 7.886770e-04 TRUE
Q96PU8 4.51212370 Q96PU8 9.440320e-04 TRUE
Q14498 4.45613928 Q14498 9.440320e-04 TRUE
P67809 4.34771600 P67809 9.440320e-04 TRUE
Q9BQG0 4.30885560 Q9BQG0 9.440320e-04 TRUE
P17480 3.96300337 P17480 1.254374e-03 TRUE
Q13641 3.76135899 Q13641 1.360252e-03 TRUE
P48634 3.75467595 P48634 1.360252e-03 TRUE
Q92841 3.69364382 Q92841 1.363061e-03 TRUE
Q4G0J3 3.51225902 Q4G0J3 1.508434e-03 TRUE
P78347 3.48614960 P78347 1.508434e-03 TRUE
Q02818 3.37506845 Q02818 1.583497e-03 TRUE
Q00341 3.32453644 Q00341 1.583497e-03 TRUE
Q13123 3.29492808 Q13123 1.583497e-03 TRUE
Q92522 3.04012137 Q92522 1.962530e-03 TRUE
Q14980 2.94105844 Q14980 2.079426e-03 TRUE
Q14694 2.85112708 Q14694 2.186483e-03 TRUE
Q2TAY7 2.77329003 Q2TAY7 2.274487e-03 TRUE
Q9NR30 2.71003141 Q9NR30 2.334717e-03 TRUE
O60427 2.56962788 O60427 2.536747e-03 TRUE
Q9P258 2.52387666 Q9P258 2.536747e-03 TRUE
Q9Y6M5 2.48409864 Q9Y6M5 2.536747e-03 TRUE
Q9BVP2 2.47416318 Q9BVP2 2.536747e-03 TRUE
Q9P0V3 2.45901842 Q9P0V3 2.536747e-03 TRUE
Q6P5R6 2.34977722 Q6P5R6 2.745317e-03 TRUE
Q92934 2.30246324 Q92934 2.769685e-03 TRUE
Q86XP3 2.28235699 Q86XP3 2.769685e-03 TRUE
O95864 2.21306382 O95864 2.814132e-03 TRUE
Q9NZB2 2.18719870 Q9NZB2 2.814132e-03 TRUE
Q9UQE7 2.18446927 Q9UQE7 2.814132e-03 TRUE
Q6P1J9 1.99688564 Q6P1J9 3.308364e-03 TRUE
P16989 1.91604606 P16989 3.497093e-03 TRUE
Q9BZK7 1.83695990 Q9BZK7 3.692164e-03 TRUE
P08865 1.78898876 P08865 3.780986e-03 TRUE
P26640 1.72526854 P26640 3.935361e-03 TRUE
Q96T58 1.68685180 Q96T58 3.936254e-03 TRUE
Q13151 1.67374468 Q13151 3.936254e-03 TRUE
Q9Y2X3 1.65737116 Q9Y2X3 3.936254e-03 TRUE
Q13451 1.59188333 Q13451 4.112153e-03 TRUE
Q9UKA9 1.53975167 Q9UKA9 4.240939e-03 TRUE
P23434 1.49773330 P23434 4.331749e-03 TRUE
Q9Y333 1.39052408 Q9Y333 4.722616e-03 TRUE
Q53EP0 1.28776035 Q53EP0 5.127610e-03 TRUE
P62906 1.22051338 P62906 5.163545e-03 TRUE
P49711 1.21009707 P49711 5.163545e-03 TRUE
P42285 1.20917043 P42285 5.163545e-03 TRUE
Q16718 1.20465092 Q16718 5.163545e-03 TRUE
P62854 1.12686153 P62854 5.447631e-03 TRUE
Q9BQ39 1.10772508 Q9BQ39 5.447631e-03 TRUE
P62750 1.09710225 P62750 5.447631e-03 TRUE
Q9H2P0 1.03826658 Q9H2P0 5.600247e-03 TRUE
Q49A26 1.03062429 Q49A26 5.600247e-03 TRUE
Q9UQB8 1.01834049 Q9UQB8 5.600247e-03 TRUE
Q96L96 0.94829592 Q96L96 5.905794e-03 TRUE
P62753 0.88507921 P62753 6.187460e-03 TRUE
P16403 0.77784969 P16403 6.650491e-03 TRUE
P62273 0.77012769 P62273 6.650491e-03 TRUE
Q99536 0.75619104 Q99536 6.650491e-03 TRUE
Q06136 0.74993066 Q06136 6.650491e-03 TRUE
Q9UQ35 0.69915601 Q9UQ35 6.655352e-03 TRUE
Q96RU2 0.69591532 Q96RU2 6.655352e-03 TRUE
P61254 0.68926951 P61254 6.655352e-03 TRUE
Q14728 0.67697163 Q14728 6.655352e-03 TRUE
Q9H1E3 0.67640450 Q9H1E3 6.655352e-03 TRUE
Q86U42 0.64251694 Q86U42 6.689712e-03 TRUE
P61313 0.62262994 P61313 6.689712e-03 TRUE
Q01780 0.61237014 Q01780 6.689712e-03 TRUE
P46782 0.60769103 P46782 6.689712e-03 TRUE
Q9HCM4 0.58420148 Q9HCM4 6.689712e-03 TRUE
P30876 0.57809873 P30876 6.689712e-03 TRUE
P39880 0.57080739 P39880 6.689712e-03 TRUE
Q9NQT5 0.56458543 Q9NQT5 6.689712e-03 TRUE
P62280 0.54023271 P62280 6.768010e-03 TRUE
P62701 0.52350618 P62701 6.796854e-03 TRUE
Q92747 0.45129299 Q92747 7.145565e-03 TRUE
P36578 0.44844527 P36578 7.145565e-03 TRUE
P62888 0.43322923 P62888 7.168392e-03 TRUE
Q5QJ74 0.40332925 Q5QJ74 7.267940e-03 TRUE
O75787 0.39570237 O75787 7.267940e-03 TRUE
P49207 0.35515105 P49207 7.478794e-03 TRUE
Q9P0M6 0.31904160 Q9P0M6 7.581754e-03 TRUE
Q6Y7W6 0.31852563 Q6Y7W6 7.581754e-03 TRUE
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Q9BXS5 -6.69443460 Q9BXS5 4.993656e-01 FALSE
Q6P1M0 -6.69444145 Q6P1M0 4.993836e-01 FALSE
Q9C0D5 -6.69444293 Q9C0D5 4.993836e-01 FALSE
Q15185 -6.69444902 Q15185 4.993849e-01 FALSE
P51153 -6.69445018 P51153 4.993849e-01 FALSE
P29144 -6.69445665 P29144 4.995269e-01 FALSE
P09543 -6.69447856 P09543 5.007025e-01 FALSE
Q9BZF1 -6.69448357 Q9BZF1 5.010516e-01 FALSE
Q92538 -6.69448566 Q92538 5.011896e-01 FALSE
Q96N64 -6.69448651 Q96N64 5.011896e-01 FALSE
Q52LJ0 -6.69448746 Q52LJ0 5.011896e-01 FALSE
P54753 -6.69448773 P54753 5.011896e-01 FALSE# 2. Do the volcano plot
ggplot(toptable_Threshold_0.05)+
geom_point(mapping = aes(x = logFC, y = -log10(adj_q_values), color = threshold_Q))+
xlab("log2FC")+
ylab("-log10 adjusted q-value")+
ylim(0, 5)+
xlim(-5, 5)+
theme(legend.position = "none",
plot.title = element_text(size = rel(1.5), hjust = 0.5),
axis.title = element_text(size = rel(1.25)))+
theme_bw()
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Histogram
hist(toptable_Dupcor$adj.P.Val, breaks = 10)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
hist(toptable_Dupcor$adj_q_values, breaks = 10)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Enrichment Test Wrangle P-adj values
# 1. Read in the comprehensive DF that contains all sample info
Full_DF %>% head() Entrez.Gene.ID Ensembl.Gene.ID Gene.Symbol Accession
1 4625 ENSG00000092054 MYH7 P12883
2 4624 ENSG00000197616 MYH6 P13533
3 7273 ENSG00000155657 TTN Q8WZ42
4 70 ENSG00000159251 ACTC1 P68032
5 58 ENSG00000143632 ACTA1 P68133
6 60 ENSG00000075624 ACTB P60709
Abundance..F1..Sample..Dox..n.a Abundance..F3..Sample..Dox..n.a
1 5.25e+10 7.41e+10
2 1.00e+09 1.47e+09
3 1.39e+10 2.08e+10
4 3.92e+10 4.11e+10
5 1.72e+07 5.81e+07
6 4.02e+09 8.43e+08
Abundance..F5..Sample..Dox..Dox Abundance..F7..Sample..Dox..Dox
1 5.28e+10 6.82e+10
2 5.11e+09 4.25e+09
3 2.19e+10 2.49e+10
4 3.76e+10 3.54e+10
5 3.85e+07 5.07e+07
6 2.04e+09 1.62e+09
Abundance..F9..Sample..Dox..Dox Abundance..F2..Control..Veh..n.a
1 6.43e+10 4.33e+10
2 2.62e+09 1.50e+09
3 2.34e+10 1.29e+10
4 3.69e+10 3.54e+10
5 6.19e+07 1.64e+07
6 1.61e+09 4.16e+09
Abundance..F4..Control..Veh..n.a Abundance..F6..Control..Veh..Veh
1 7.41e+10 7.00e+10
2 1.17e+09 2.42e+09
3 2.25e+10 2.52e+10
4 2.96e+10 3.56e+10
5 3.44e+07 5.42e+07
6 6.45e+08 1.92e+09
Abundance..F8..Control..Veh..Veh Abundance..F10..Control..Veh..Veh
1 5.64e+10 5.26e+10
2 3.67e+09 3.27e+09
3 2.46e+10 2.21e+10
4 2.98e+10 2.91e+10
5 3.36e+07 4.05e+07
6 1.81e+09 1.56e+09# 2.
# Get set of DE proteins as per BH adjusted P-value
DE_proteins_Padj <- toptable_Threshold_0.05 %>%
filter(adj.P.Val < 0.05) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% DE_proteins_Padj)
# Subset the data frame
subset_Full_data <- Full_DF[rows, ]
# Here are the SYMBOL IDs for the DE proteins as per BH adj P value < 0.05
DE_SYMBOL_Padj <- subset_Full_data$Gene.Symbol %>% unique() %>% na.omit()
DE_SYMBOL_Padj [1] "H1-4" "TUBB3"
[3] "NPM1" "NCL"
[5] "H1-2" "RPL4"
[7] "KRT2" ""
[9] "PRDX1" "DDX17"
[11] "RACK1" "RPS3"
[13] "YBX1" "DDX5"
[15] "GTF2I" "RPL7A"
[17] "HSPA4" "RPS4X"
[19] "RPS3A" "PPP1CC"
[21] "PRMT1" "DDX3X"
[23] "PABPC1" "RPSA"
[25] "TP53BP1" "TKT"
[27] "RPL3" "RPL8"
[29] "RPS9" "HNRNPA0"
[31] "SRRM2" "RPS14"
[33] "NOP58" "VAT1"
[35] "NUMA1" "RPS18"
[37] "RPS6" "PTBP2"
[39] "CHD4" "FSCN1"
[41] "RPS11" "PABPC4"
[43] "RPL27" "RPS20"
[45] "VARS1" "SERBP1"
[47] "RPL17" "G3BP1"
[49] "ACAD8" "YBX3"
[51] "RPL30" "PABPN1"
[53] "RPL10A" "NDUFA8"
[55] "CAPRIN1" "RPS15A"
[57] "RPL9; RPL9P7; RPL9P8; RPL9P9" "HDLBP"
[59] "RPS5" "RPL26"
[61] "RBM39" "DDX42"
[63] "RPS16" "USP28"
[65] "RPS12" "DPYSL2"
[67] "RPL15" "ECSIT"
[69] "ARPC1A" "RPL23A"
[71] "CORO1B" "RPL24"
[73] "RSL1D1" "LMOD2"
[75] "ANKRD1" "SARNP"
[77] "CDC42BPB" "ACLY"
[79] "RPL27A" "MYBBP1A"
[81] "DDX21" "RPL21"
[83] "FAM120A" "RPS15"
[85] "UBTF" "TRIM54"
[87] "RPL14" "H1-10"
[89] "RPS17" "RPL29"
[91] "CDC5L" "GOLIM4"
[93] "SMU1" "RPS24"
[95] "RPL35A" "RPS19"
[97] "PLRG1" "USP10"
[99] "EPHA4" "TIMMDC1"
[101] "RPL34" "PNN"
[103] "GLYR1" "RNMT"
[105] "DDX50" "THBS1"
[107] "NDUFA5" "RPS25"
[109] "NUCB1" "RPS26"
[111] "RPLP2" "TRIM63"
[113] "RPL32" "SNU13"
[115] "RPL36AL" "GCSH"
[117] "RPL31" "EPB41L5"
[119] "SLC30A1" "FNDC3B"
[121] "DMAC2L" "RPL36A"
[123] "ZNF638" "LARP7"
[125] "PPP4C" "RPL37A"
[127] "TBL1XR1" "IK"
[129] "GJA1" "MRPL28"
[131] "VLDLR" "LRRN4"
[133] "NUCKS1" "LIN7C"
[135] "FADS1" "MBNL1"
[137] "RPS10" "MAP1LC3B"
[139] "CHTOP" "RPL36"
[141] "ADNP" "STX8"
[143] "ALPK3" "POLR2B"
[145] "ATP6AP2" "NAT10"
[147] "MTREX" "PRRC2A"
[149] "TMEM192" "RCC2"
[151] "DPP3" "CDK12"
[153] "CAND2" "RBMS1"
[155] "VCAM1" "CUX1"
[157] "DDX47" "RPS29"
[159] "QKI" "RTRAF"
[161] "FADS2" "MACROH2A2"
[163] "CD46" "Creb1; CREB1; LOC101356881"
[165] "TFB1M" "CDC73"
[167] "MRPS26" "DDX18"
[169] "FAM3C" "EDNRA"
[171] "RPS28" "MFSD10"
[173] "GNL3" "POLR2A"
[175] "SLC1A5" "DDX27"
[177] "BAIAP2" "S1PR1"
[179] "AHSA1" "EXOSC3"
[181] "CWC15" "EXOSC7"
[183] "YTHDF3" "LSM2"
[185] "RRP8" "VASN"
[187] "SKIC8" "LARP4"
[189] "EXOSC10" "SMNDC1"
[191] "SH3BP4" "SMC3"
[193] "LRRC10" "GIGYF2"
[195] "DPF3" "CARD19"
[197] "SIPA1L3" "PAK4"
[199] "DDX41" "LGR4"
[201] "PES1" "TPBG"
[203] "BNIP3" "POLR2E"
[205] "RPL22L1" "CTCF"
[207] "PPP1R8" "FKBP5"
[209] "MRC2" "METTL17"
[211] "ST3GAL1" "ARID2"
[213] "NINL" "SPEN"
[215] "UBE2Z" "POLR1E"
[217] "PCDHGA3" "MTIF3"
[219] "KDSR" "CCNA1"
[221] "BAD" "TBCEL"
[223] "TRIM21" "MAP7D3" # Get background Symbol IDs
All_proteins_tested <- toptable_Threshold_0.05 %>%
filter(adj.P.Val < 1) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% All_proteins_tested)
# Subset the data frame
subset_back_data <- Full_DF[rows, ]
Background_SYMBOL <- subset_back_data$Gene.Symbol %>% unique() %>% na.omit()
Background_SYMBOL [1] "MYH7"
[2] "MYH6"
[3] "TTN"
[4] "ACTC1"
[5] "ACTA1"
[6] "ACTB"
[7] "ACTG1"
[8] "MYH1"
[9] "MYH3"
[10] "MYH2"
[11] "ATP5F1B"
[12] "ATP5F1A"
[13] "MYH8"
[14] "MYH13"
[15] "MYBPC3"
[16] "HSPD1"
[17] "FLNC"
[18] "SPTAN1"
[19] "SPTBN1"
[20] "AHNAK"
[21] "TPM1"
[22] "GAPDH"
[23] "SLC25A4"
[24] "ATP2A2"
[25] "XIRP1"
[26] "ACTN2"
[27] "ACO2"
[28] "SLC25A6"
[29] "IDH2"
[30] "TNNT2"
[31] "HSPA5"
[32] "SLC25A5"
[33] "VDAC1"
[34] "HK1"
[35] "LMNA"
[36] "MYOM1"
[37] "ACTN1"
[38] "MDH2"
[39] "SORBS2"
[40] "HADHA"
[41] "LDB3"
[42] "DMD"
[43] "OBSCN"
[44] "HSPA8"
[45] "ATP1A1"
[46] "GOT2"
[47] "HNRNPA2B1"
[48] "PLEC"
[49] "VDAC2"
[50] "SERPINH1"
[51] "OGDH"
[52] "MGST3"
[53] "HSP90B1"
[54] "TPM2"
[55] "AIFM1"
[56] ""
[57] "KRT1"
[58] "P4HB"
[59] "HSPA9"
[60] "ALDOA"
[61] "SLC25A3"
[62] "ANXA2"
[63] "VCL"
[64] "POTEKP"
[65] "SYNPO2L"
[66] "VIM"
[67] "NEBL"
[68] "CLTC"
[69] "MYL3"
[70] "PRKDC"
[71] "HADHB"
[72] "FH"
[73] "MYL2"
[74] "LRPPRC"
[75] "TPM3"
[76] "EEF1A1"
[77] "UQCRC2"
[78] "FLNA"
[79] "TUBB"
[80] "ACTN4"
[81] "CTNNA1"
[82] "CKMT2"
[83] "PDHA1"
[84] "SDHA"
[85] "IMMT"
[86] "TUBB4B"
[87] "UQCRC1"
[88] "DSP"
[89] "CANX"
[90] "SVIL"
[91] "PKM"
[92] "RTN4"
[93] "HNRNPU"
[94] "KRT18"
[95] "PDHB"
[96] "MYL4"
[97] "PDIA3"
[98] "KRT8"
[99] "PRDX3"
[100] "MYH9"
[101] "NES"
[102] "FHL2"
[103] "ATP2B4"
[104] "HNRNPL"
[105] "NDUFS1"
[106] "SPTB"
[107] "ANXA6"
[108] "ATP5F1C"
[109] "ATP1A3"
[110] "CS"
[111] "CKAP4"
[112] "NNT"
[113] "ENO1"
[114] "CALR"
[115] "TPM4"
[116] "DLD"
[117] "TLN1"
[118] "KRT9"
[119] "HNRNPK"
[120] "HNRNPA1"
[121] "GLUD1"
[122] "HSPB1"
[123] "PGK1"
[124] "TUBB2A"
[125] "JUP"
[126] "H1-4"
[127] "ANK3"
[128] "PDLIM5"
[129] "SLC8A1"
[130] "KRT10"
[131] "MYO18A"
[132] "ACAT1"
[133] "ATP1A2"
[134] "PKP2"
[135] "GANAB"
[136] "DYNC1H1"
[137] "VCP"
[138] "KTN1"
[139] "ETFA"
[140] "DECR1"
[141] "DYSF"
[142] "TUBA1A"
[143] "ACAA2"
[144] "IARS2"
[145] "MYH15"
[146] "IDH3A"
[147] "CYB5R3"
[148] "HNRNPM"
[149] "EEF1A2"
[150] "HSP90AB1"
[151] "CSRP3"
[152] "GATD3B"
[153] "PPIF"
[154] "MACF1"
[155] "HSP90AA1"
[156] "PHB2"
[157] "ALB"
[158] "OPA1"
[159] "MYH10"
[160] "VDAC3"
[161] "ILF3"
[162] "DHX9"
[163] "SLC25A12"
[164] "RPS27A"
[165] "LMO7"
[166] "PDLIM1"
[167] "TRIM28"
[168] "TUBB3"
[169] "HSD17B10"
[170] "PPIB"
[171] "EPB41L3"
[172] "ITGB1"
[173] "NPM1"
[174] "COX4I1"
[175] "TPI1"
[176] "NDUFS2"
[177] "HSPE1"
[178] "H1-5"
[179] "SYNPO2"
[180] "RPN1"
[181] "SERPINB14"
[182] "LMNB1"
[183] "NONO"
[184] "TUBA4A"
[185] "ACADVL"
[186] "MYL7"
[187] "NCL"
[188] "HK2"
[189] "HSPA1B"
[190] "ABLIM1"
[191] "H2BC5"
[192] "CDH2"
[193] "SLC25A11"
[194] "MATR3"
[195] "PDIA4"
[196] "CTNNB1"
[197] "H1-2"
[198] "GPI"
[199] "SOD2"
[200] "XRCC5"
[201] "PHB1"
[202] "ANK2"
[203] "ACADM"
[204] "MYOZ2"
[205] "NEXN"
[206] "CTSB"
[207] "ENO3"
[208] "ASAH1"
[209] "DLST"
[210] "CTNND1"
[211] "ETFB"
[212] "EPRS1"
[213] "PDIA6"
[214] "ITGAV"
[215] "TNNI1"
[216] "CTSD"
[217] "DLAT"
[218] "H2BC21"
[219] "H1-3"
[220] "MDH1"
[221] "CYB5R1"
[222] "KHSRP"
[223] "SFPQ"
[224] "TLN2"
[225] "SUCLA2"
[226] "HADH"
[227] "PFKP"
[228] "RRBP1"
[229] "HNRNPA3"
[230] "RYR2"
[231] "TOMM70"
[232] "ECH1"
[233] "BCAM"
[234] "ALDH2"
[235] "EZR"
[236] "GLS"
[237] "MTCH2"
[238] "FLNB"
[239] "AFG3L2"
[240] "HYOU1"
[241] "NDUFV1"
[242] "AKAP2"
[243] "SMYD1"
[244] "TFRC"
[245] "NCAM1"
[246] "DES"
[247] "PYGB"
[248] "RPL4"
[249] "SND1"
[250] "TUBB6"
[251] "LONP1"
[252] "DPYSL3"
[253] "XRCC6"
[254] "HSD17B4"
[255] "ALDH4A1"
[256] "EEA1"
[257] "HNRNPR"
[258] "KRT2"
[259] "UQCRFS1"
[260] "SFXN1"
[261] "PGAM1"
[262] "EEF2"
[263] "RPN2"
[264] "TRAP1"
[265] "MSN"
[266] "PRDX4"
[267] "BVES"
[268] "SF3B1"
[269] "SHMT2"
[270] "IGF2BP1"
[271] "SLC25A13"
[272] "PARP1"
[273] "PRDX1"
[274] "UNC45B"
[275] "NDUFA9"
[276] "ATP5PO"
[277] "IDH3B"
[278] "DDX17"
[279] "OXCT1"
[280] "ALDH6A1"
[281] "LAMB1"
[282] "PALLD"
[283] "CNN1"
[284] "RACK1"
[285] "HNRNPD"
[286] "CYC1"
[287] "KRT19"
[288] "NDUFA10"
[289] "AP2B1"
[290] "EEF1G"
[291] "DDX39B"
[292] "LAMC1"
[293] "ACAA1"
[294] "SOD1"
[295] "HRC"
[296] "RBMX"
[297] "KRT16"
[298] "KRT14"
[299] "MFGE8"
[300] "LDHA"
[301] "ALDH7A1"
[302] "NIPSNAP2"
[303] "PRPF19"
[304] "NDUFS3"
[305] "ATP1B1"
[306] "UGGT1"
[307] "MAP4"
[308] "HNRNPH1"
[309] "RPS3"
[310] "OBSL1"
[311] "BSG"
[312] "MYL6"
[313] "PPP1R12B"
[314] "IGF2R"
[315] "ECHS1"
[316] "FUBP1"
[317] "ATP2B1"
[318] "PPP1CB"
[319] "PITRM1"
[320] "MAVS"
[321] "CRAT"
[322] "WDR1"
[323] "LDHB"
[324] "AP2A1"
[325] "LMNB2"
[326] "HNRNPH2"
[327] "SRSF1"
[328] "SRSF3"
[329] "ATAD3A"
[330] "ADD1"
[331] "ACOT9"
[332] "CHCHD3"
[333] "PRDX5"
[334] "ILF2"
[335] "PSMD2"
[336] "SYNCRIP"
[337] "ACOT1"
[338] "GNAI2"
[339] "CRIP2"
[340] "ACOT2"
[341] "PTBP1"
[342] "RFTN1"
[343] "ALDOC"
[344] "LETM1"
[345] "ABAT"
[346] "GOT1"
[347] "SNTA1"
[348] "PPP1R12A"
[349] "PGM5"
[350] "ELAVL1"
[351] "MCCC2"
[352] "PRDX2"
[353] "ECI2"
[354] "SUCLG1"
[355] "ALDH3A2"
[356] "UBA1"
[357] "ACSF2"
[358] "CPVL"
[359] "CTNNA3"
[360] "KRT6A"
[361] "QARS1"
[362] "YBX1"
[363] "MYO1C"
[364] "TIMM44"
[365] "DDX5"
[366] "SLMAP"
[367] "PDHA2"
[368] "SLC16A1"
[369] "TJP1"
[370] "EIF3A"
[371] "RDX"
[372] "IGF2BP3"
[373] "PRKCSH"
[374] "HSPA1L"
[375] "IDH3G"
[376] "TMPO"
[377] "CCT2"
[378] "GTF2I"
[379] "CPT2"
[380] "COPA"
[381] "EMC1"
[382] "DDB1"
[383] "VAPA"
[384] "KRT5"
[385] "TOMM40"
[386] "PPP1CA"
[387] "CKM"
[388] "ME2"
[389] "PCCA"
[390] "PMPCA"
[391] "ACADSB"
[392] "CCAR2"
[393] "ECI1"
[394] "POPDC2"
[395] "ACAD9"
[396] "AK3"
[397] "RHOA"
[398] "DDX1"
[399] "SAMM50"
[400] "UGP2"
[401] "VAPB"
[402] "UTRN"
[403] "TMOD1"
[404] "FXR1"
[405] "EIF4G1"
[406] "HSDL2"
[407] "ETFDH"
[408] "AASS"
[409] "FLOT1"
[410] "AK2"
[411] "RPL7A"
[412] "ACSL1"
[413] "DGLUCY"
[414] "LMAN1"
[415] "HSPA4"
[416] "IVD"
[417] "CCT8"
[418] "FDXR"
[419] "RAB2A"
[420] "SUGP2"
[421] "NIPSNAP1"
[422] "CCT3"
[423] "GNB1"
[424] "RPL6"
[425] "LAP3"
[426] "LARS1"
[427] "KPNB1"
[428] "ITGA7"
[429] "ATAD1"
[430] "MT-CO2"
[431] "CALU"
[432] "RPS4X"
[433] "FARP1"
[434] "MYH14"
[435] "CTTN"
[436] "MCCC1"
[437] "HNRNPUL2"
[438] "MTDH"
[439] "PLEKHA7"
[440] "CALD1"
[441] "TNPO1"
[442] "RPS3A"
[443] "GSTK1"
[444] "FLOT2"
[445] "TPR"
[446] "CRYZ"
[447] "SDHB"
[448] "VWA8"
[449] "SLC3A2"
[450] "H2AC20"
[451] "TOP2B"
[452] "SF3A1"
[453] "LRPAP1"
[454] "DARS2"
[455] "MFN2"
[456] "PPP1CC"
[457] "TRIM55"
[458] "CSPG4"
[459] "DSG2"
[460] "NACA"
[461] "ASPH"
[462] "PDHX"
[463] "SF3B2"
[464] "BCAT2"
[465] "CAVIN1"
[466] "CORO6"
[467] "CRYAB"
[468] "PRMT1"
[469] "FKBP10"
[470] "RBMXL1"
[471] "SEPTIN7"
[472] "NSF"
[473] "RPL7"
[474] "PDK1"
[475] "HCFC1"
[476] "SUCLG2"
[477] "SF3B3"
[478] "ATP5PB"
[479] "GLB1"
[480] "PLXNB2"
[481] "FUS"
[482] "DDX3X"
[483] "PGM1"
[484] "LMAN2"
[485] "HIBADH"
[486] "CCDC141"
[487] "AGK"
[488] "CFL1"
[489] "CAMK2D"
[490] "CCT4"
[491] "MAP1B"
[492] "LAMB2"
[493] "TXNDC5"
[494] "RPL5"
[495] "MYO18B"
[496] "HMGB1"
[497] "PRKAR2A"
[498] "GNB2"
[499] "RAB1A"
[500] "EIF3C"
[501] "ACADS"
[502] "TMED10"
[503] "MRPS22"
[504] "YWHAE"
[505] "PABPC1"
[506] "RPSA"
[507] "MTX2"
[508] "PMPCB"
[509] "DAP3"
[510] "RHOT2"
[511] "NDUFA12"
[512] "P4HA1"
[513] "MCAM"
[514] "LSS"
[515] "TP53BP1"
[516] "GFM1"
[517] "NOMO2"
[518] "RAB11B"
[519] "KRT17"
[520] "PGRMC1"
[521] "NME2"
[522] "ARVCF"
[523] "DARS1"
[524] "PCYOX1"
[525] "PSMA1"
[526] "PTCD3"
[527] "BCKDHA"
[528] "GAA"
[529] "PYGM"
[530] "CPT1A"
[531] "RAB10"
[532] "TPP1"
[533] "TKT"
[534] "NOMO1"
[535] "ALDH9A1"
[536] "NPTN"
[537] "AP2A2"
[538] "IGF2BP2"
[539] "KRT7"
[540] "PLD3"
[541] "RPL3"
[542] "ENO2"
[543] "RTCB"
[544] "MOGS"
[545] "APMAP"
[546] "PTGES2"
[547] "JPH2"
[548] "HNRNPDL"
[549] "DBN1"
[550] "DAG1"
[551] "CORO1C"
[552] "HNRNPUL1"
[553] "GYS1"
[554] "FECH"
[555] "SEC23A"
[556] "RPL8"
[557] "HP1BP3"
[558] "NOP56"
[559] "SCCPDH"
[560] "OCIAD1"
[561] "PLN"
[562] "FBL"
[563] "LNPEP"
[564] "TAF15"
[565] "RPS9"
[566] "GPC1"
[567] "CAP2"
[568] "SNRNP200"
[569] "AGPS"
[570] "RAB14"
[571] "PPA2"
[572] "MRPL37"
[573] "SSB"
[574] "HSPG2"
[575] "IARS1"
[576] "TIMM50"
[577] "APOO"
[578] "RPS8"
[579] "AP2M1"
[580] "CCT7"
[581] "HNRNPA0"
[582] "PPP2R1A"
[583] "PNPT1"
[584] "GPD2"
[585] "U2AF2"
[586] "PBXIP1"
[587] "STOML2"
[588] "PRKAR1A"
[589] "CCT5"
[590] "SRRT"
[591] "AK4"
[592] "ERP29"
[593] "ARF3"
[594] "SRRM2"
[595] "PSMD11"
[596] "DBT"
[597] "PSMD1"
[598] "LRRC59"
[599] "ACTR3"
[600] "RAB35"
[601] "KIDINS220"
[602] "RARS1"
[603] "LASP1"
[604] "RBM14"
[605] "SPEG"
[606] "COX5A"
[607] "SNRNP70"
[608] "RPS7"
[609] "RPL13"
[610] "PEBP1"
[611] "CISD1"
[612] "CAND1"
[613] "PSMC1"
[614] "SRPRB"
[615] "SFXN3"
[616] "RAB7A"
[617] "ERP44"
[618] "EIF3L"
[619] "DNAJC11"
[620] "GBE1"
[621] "RPS14"
[622] "CLIC4"
[623] "PRPF8"
[624] "ATAD3B"
[625] "EIF4A1"
[626] "PFN1"
[627] "EIF2S3"
[628] "CAPZB"
[629] "EIF4A2"
[630] "CCT6A"
[631] "NPC2"
[632] "BCAP31"
[633] "TRMT10C"
[634] "MRPL15"
[635] "IPO5"
[636] "SARS2"
[637] "GOLGB1"
[638] "NOP58"
[639] "RAB8A"
[640] "AGL"
[641] "ARL6IP5"
[642] "SRSF6"
[643] "RAB1B"
[644] "MLYCD"
[645] "PSMC4"
[646] "RBBP7"
[647] "RAC1"
[648] "ESYT1"
[649] "PSMC5"
[650] "COQ9"
[651] "PSMD3"
[652] "LARS2"
[653] "CADM1"
[654] "CNP"
[655] "GLG1"
[656] "C1QBP"
[657] "SLC25A24"
[658] "NUP210"
[659] "ACSL3"
[660] "SLC25A20"
[661] "ERO1A"
[662] "NUDT21"
[663] "PTGFRN"
[664] "CACNA2D1"
[665] "RAB6A"
[666] "TPP2"
[667] "AQP1"
[668] "GSN"
[669] "CKMT1A; CKMT1B"
[670] "COPB2"
[671] "SSBP1"
[672] "NSDHL"
[673] "GFM2"
[674] "VAT1"
[675] "PGRMC2"
[676] "FUBP3"
[677] "USO1"
[678] "DNAJB11"
[679] "TST"
[680] "PSMA7"
[681] "PDLIM3"
[682] "GRHPR"
[683] "TCP1"
[684] "ACBD3"
[685] "NME1"
[686] "PCBP1"
[687] "MYL9"
[688] "ALYREF"
[689] "PSMD13"
[690] "DDOST"
[691] "NUMA1"
[692] "MMUT"
[693] "TNNI3"
[694] "THRAP3"
[695] "HEXB"
[696] "FXR2"
[697] "PSMD12"
[698] "MRPS9"
[699] "NIPSNAP3A"
[700] "ADD3"
[701] "BCLAF1"
[702] "RAI14"
[703] "RPS18"
[704] "RPS6"
[705] "RPLP0"
[706] "YWHAZ"
[707] "PAM"
[708] "PGAM2"
[709] "LEMD2"
[710] "HNRNPF"
[711] "ATP6V1B2"
[712] "SEPTIN2"
[713] "PLOD1"
[714] "PSMB5"
[715] "TMX2"
[716] "RAB2B"
[717] "STIP1"
[718] "CPOX"
[719] "FERMT2"
[720] "MRPL3"
[721] "ACE2"
[722] "ATP6V0A1"
[723] "COL18A1"
[724] "PTBP2"
[725] "ARHGAP1"
[726] "HSD17B12"
[727] "AFDN"
[728] "STBD1"
[729] "AIMP1"
[730] "SAFB"
[731] "P4HA2"
[732] "SLC2A1"
[733] "EIF3B"
[734] "TARS2"
[735] "RAN"
[736] "ALDH5A1"
[737] "CHD4"
[738] "CASQ2"
[739] "FSCN1"
[740] "MTHFD1L"
[741] "STING1"
[742] "ALDH18A1"
[743] "YWHAG"
[744] "GNS"
[745] "RPS11"
[746] "MRPS5"
[747] "FASN"
[748] "CFL2"
[749] "POR"
[750] "PFKM"
[751] "MANBA"
[752] "TECR"
[753] "REEP5"
[754] "SUOX"
[755] "LAMA5"
[756] "FAHD2A"
[757] "ABCD3"
[758] "TACO1"
[759] "EIF4A3"
[760] "PABPC4"
[761] "GDI2"
[762] "RANBP2"
[763] "CTSC"
[764] "SPATA20"
[765] "KHDRBS1"
[766] "PSMD6"
[767] "RPL27"
[768] "SIRPA"
[769] "RPS20"
[770] "BCS1L"
[771] "MARS1"
[772] "PRKACA"
[773] "VARS1"
[774] "ADH5"
[775] "TARDBP"
[776] "RPL13A"
[777] "HSPB7"
[778] "CLPX"
[779] "AHCY"
[780] "CPSF6"
[781] "PCCB"
[782] "PARK7"
[783] "EPHA2"
[784] "SERBP1"
[785] "AKR1B1"
[786] "HDHD5"
[787] "RUVBL2"
[788] "GCDH"
[789] "SYNJ2BP"
[790] "PSMC2"
[791] "G3BP2"
[792] "ABHD11"
[793] "HCCS"
[794] "SMARCC2"
[795] "YLPM1"
[796] "PCBP2"
[797] "TGM2"
[798] "TAGLN"
[799] "EIF5A"
[800] "MYL12B"
[801] "RRAS"
[802] "CTSA"
[803] "RHOT1"
[804] "VPS35"
[805] "PRDX6"
[806] "RPL17"
[807] "G3BP1"
[808] "BAK1"
[809] "DCTN2"
[810] "TRIOBP"
[811] "SEC24C"
[812] "ZFR"
[813] "CLPB"
[814] "SGSH"
[815] "PSMA6"
[816] "EWSR1"
[817] "HNRNPAB"
[818] "ARMCX1"
[819] "ACAD8"
[820] "LRRC47"
[821] "TCOF1"
[822] "YBX3"
[823] "ALCAM"
[824] "RCN1"
[825] "EEF1D"
[826] "PUF60"
[827] "TOP1"
[828] "TNNC1"
[829] "SRPRA"
[830] "RDH13"
[831] "HSDL1"
[832] "CAV1"
[833] "LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"
[834] "NDUFV2"
[835] "PALM2"
[836] "COPB1"
[837] "SCP2"
[838] "TMED9"
[839] "MTCH1"
[840] "RPL30"
[841] "SACM1L"
[842] "STRN"
[843] "EIF3D"
[844] "CIRBP"
[845] "GNA11"
[846] "MRPL38"
[847] "MYADM"
[848] "PABPN1"
[849] "ABHD16A"
[850] "EIF3E"
[851] "PA2G4"
[852] "RAP1A"
[853] "ATP1B4"
[854] "KIF5B"
[855] "PICALM"
[856] "LNPK"
[857] "TMEM43"
[858] "RPL10A"
[859] "ZYX"
[860] "SSRP1"
[861] "NDUFA8"
[862] "EFTUD2"
[863] "ANXA1"
[864] "ATP5MG"
[865] "NAP1L4"
[866] "LRP1"
[867] "GNAS"
[868] "PIGS"
[869] "GPX1"
[870] "ERLIN2"
[871] "SCARB2"
[872] "ERBB2"
[873] "ANP32A"
[874] "VAMP3"
[875] "H2AC25"
[876] "MIPEP"
[877] "SF3A3"
[878] "COLGALT1"
[879] "PGAM5"
[880] "DAZAP1"
[881] "NDUFA11"
[882] "CD59"
[883] "CLPTM1"
[884] "MPC2"
[885] "HSPH1"
[886] "NARS1"
[887] "WFS1"
[888] "MLEC"
[889] "DHX15"
[890] "TOR1AIP1"
[891] "SEPTIN9"
[892] "GNAI1"
[893] "RPL19"
[894] "SCAMP3"
[895] "CD81"
[896] "ARL8B"
[897] "NAP1L1"
[898] "HMOX2"
[899] "BUB3"
[900] "CAPRIN1"
[901] "RPS13"
[902] "PLEKHA5"
[903] "HACD3"
[904] "EMD"
[905] "NDUFS6"
[906] "RPS15A"
[907] "SMARCA4"
[908] "RPL9; RPL9P7; RPL9P8; RPL9P9"
[909] "STT3B"
[910] "SGPL1"
[911] "RBBP4"
[912] "HDLBP"
[913] "ANXA3"
[914] "CAP1"
[915] "ATP6V1A"
[916] "GNB4"
[917] "CLIC1"
[918] "PSMA3"
[919] "CRELD1"
[920] "FLII"
[921] "ADCY5"
[922] "LGALS3BP"
[923] "RPS5"
[924] "RPL26"
[925] "RAB6B"
[926] "PELP1"
[927] "CAPZA2"
[928] "PTK7"
[929] "RBM39"
[930] "SRSF2"
[931] "ATP5F1D"
[932] "DDX42"
[933] "PDK3"
[934] "GHITM"
[935] "RPS16"
[936] "MRPS11"
[937] "RAP1B"
[938] "PLBD2"
[939] "MRPS27"
[940] "USP28"
[941] "MGST1"
[942] "UFL1"
[943] "MRPL39"
[944] "FHL1"
[945] "SUPT16H"
[946] "APOE"
[947] "HIBCH"
[948] "ACP2"
[949] "RPS12"
[950] "SART3"
[951] "PTPN1"
[952] "CAT"
[953] "ERMP1"
[954] "ACIN1"
[955] "STX7"
[956] "TXNRD2"
[957] "SCO1"
[958] "RDH11"
[959] "UBAP2L"
[960] "POLDIP2"
[961] "RAB21"
[962] "GM2A"
[963] "PDPR"
[964] "GNAI3"
[965] "RUVBL1"
[966] "RPL11"
[967] "KARS1"
[968] "HNRNPC"
[969] "SLTM"
[970] "MRPL13"
[971] "EIF4G2"
[972] "RAB12"
[973] "HMGB2"
[974] "ENDOG"
[975] "PSMB1"
[976] "ACOX1"
[977] "CDC42"
[978] "DPYSL2"
[979] "LGALS1"
[980] "PYCR1"
[981] "SEC13"
[982] "DPP7"
[983] "EIF3I"
[984] "SF1"
[985] "RPL15"
[986] "CAPZA1"
[987] "STRAP"
[988] "ABHD12"
[989] "SRSF7"
[990] "TOP2A"
[991] "TSFM"
[992] "S100A10"
[993] "PCK2"
[994] "RPL12"
[995] "MRPS31"
[996] "HMGCL"
[997] "FKBP8"
[998] "YWHAQ"
[999] "DNAJC13"
[1000] "ITGA3"
[1001] "ARSB"
[1002] "TMX3"
[1003] "SEC61A1"
[1004] "SPCS2"
[1005] "SCAMP1"
[1006] "RPL18"
[1007] "NADK2"
[1008] "HIGD1A"
[1009] "MRPL44"
[1010] "RAD23B"
[1011] "PYGL"
[1012] "RBM4"
[1013] "NDUFS8"
[1014] "HEXA"
[1015] "RNH1"
[1016] "FAF2"
[1017] "POFUT1"
[1018] "ARF4"
[1019] "SLC2A3"
[1020] "DNAJC10"
[1021] "CSNK2A1"
[1022] "NPEPPS"
[1023] "PDP1"
[1024] "NAPA"
[1025] "APEX1"
[1026] "ACTR1A"
[1027] "NASP"
[1028] "PDLIM7"
[1029] "CASK"
[1030] "RPL22"
[1031] "ARCN1"
[1032] "CSRP2"
[1033] "APOOL"
[1034] "NCLN"
[1035] "PIGT"
[1036] "DDX23"
[1037] "FARSB"
[1038] "ECSIT"
[1039] "IBA57"
[1040] "PSMC3"
[1041] "ARPC1A"
[1042] "SLC25A1"
[1043] "ARL8A"
[1044] "ITGA5"
[1045] "CLGN"
[1046] "TBRG4"
[1047] "RBM25"
[1048] "PEX11B"
[1049] "CLIC5"
[1050] "RPL23A"
[1051] "TCERG1"
[1052] "RPL35"
[1053] "HDAC2"
[1054] "RHOG"
[1055] "ACOX3"
[1056] "NIPSNAP3B"
[1057] "ARMCX2"
[1058] "RALA"
[1059] "NDUFA13"
[1060] "HNRNPH3"
[1061] "ABCD1"
[1062] "MRPS2"
[1063] "NID1"
[1064] "NUP93"
[1065] "NFS1"
[1066] "XRN2"
[1067] "FKBP3"
[1068] "YES1"
[1069] "RTN3"
[1070] "CORO1B"
[1071] "NDUFS7"
[1072] "TMEM65"
[1073] "PLA2G15"
[1074] "PRKAR2B"
[1075] "H1-0"
[1076] "H2AZ2"
[1077] "RPS2"
[1078] "COX6B1"
[1079] "DCXR"
[1080] "PSMD4"
[1081] "NDUFB9"
[1082] "GATM"
[1083] "ACTL6A"
[1084] "SPG7"
[1085] "ATP1B3"
[1086] "PSMC6"
[1087] "HOMER1"
[1088] "FKBP9"
[1089] "ACSL4"
[1090] "DSTN"
[1091] "PSMA2"
[1092] "MRPL4"
[1093] "SLC12A4"
[1094] "SEPTIN8"
[1095] "GALNT2"
[1096] "RPL24"
[1097] "MRPL1"
[1098] "ITGB5"
[1099] "CSDE1"
[1100] "PDS5B"
[1101] "PRPF6"
[1102] "SMCHD1"
[1103] "MICOS13"
[1104] "SUPV3L1"
[1105] "HMGA2"
[1106] "ABCB7"
[1107] "ERGIC1"
[1108] "MRPL9"
[1109] "SLIRP"
[1110] "DNM2"
[1111] "CAPN1"
[1112] "RAB18"
[1113] "CYB5B"
[1114] "CCDC47"
[1115] "TM9SF4"
[1116] "TMEM126A"
[1117] "MRPL24"
[1118] "FUNDC2"
[1119] "ATP5MF"
[1120] "MRPS34"
[1121] "GGH"
[1122] "PTDSS2"
[1123] "RSL1D1"
[1124] "HUWE1"
[1125] "SLC12A7"
[1126] "U2AF1"
[1127] "DEK"
[1128] "SRSF4"
[1129] "RALY"
[1130] "DCTN1"
[1131] "XPO1"
[1132] "ATP13A1"
[1133] "DTNA"
[1134] "LMOD2"
[1135] "AARS2"
[1136] "MRPL16"
[1137] "GORASP2"
[1138] "H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"
[1139] "MYOF"
[1140] "DDX46"
[1141] "MRPL19"
[1142] "MRPS23"
[1143] "PSMA4"
[1144] "ANKRD1"
[1145] "NAXE"
[1146] "PSMD7"
[1147] "CBR4"
[1148] "SCFD1"
[1149] "SLC27A6"
[1150] "STYXL2"
[1151] "PCDH7"
[1152] "FAHD1"
[1153] "GNAQ"
[1154] "MELTF"
[1155] "CDK5RAP3"
[1156] "SARNP"
[1157] "MRPL2"
[1158] "CMAS"
[1159] "MAPRE1"
[1160] "ABCB10"
[1161] "HBA1; HBA2"
[1162] "SEPTIN11"
[1163] "LAMTOR1"
[1164] "SEC63"
[1165] "PSMB7"
[1166] "RAB4A"
[1167] "PLOD3"
[1168] "EIF4E"
[1169] "PRCP"
[1170] "USP7"
[1171] "CCAR1"
[1172] "PSPC1"
[1173] "HARS2"
[1174] "PHGDH"
[1175] "NUP155"
[1176] "HSD17B8"
[1177] "SET"
[1178] "NSFL1C"
[1179] "CSNK1A1"
[1180] "STRN3"
[1181] "QDPR"
[1182] "DYNC1LI1"
[1183] "SRC"
[1184] "RTN4IP1"
[1185] "DKC1"
[1186] "PRKACB"
[1187] "CELF2"
[1188] "RPL18A"
[1189] "LPP"
[1190] "XPR1"
[1191] "CKAP5"
[1192] "PRPF4"
[1193] "STT3A"
[1194] "KRT77"
[1195] "ACTR2"
[1196] "SMARCA2"
[1197] "DHX30"
[1198] "TM9SF2"
[1199] "TMTC3"
[1200] "SEC61A2"
[1201] "RALB"
[1202] "YWHAB"
[1203] "RDH14"
[1204] "IGFBP7"
[1205] "CDKN2AIP"
[1206] "QPRT"
[1207] "GDI1"
[1208] "SLC25A10"
[1209] "CDC42BPB"
[1210] "EHD1"
[1211] "HM13"
[1212] "MTARC2"
[1213] "IDH1"
[1214] "PSMA5"
[1215] "TMEM245"
[1216] "DNAJA1"
[1217] "TMEM165"
[1218] "HMGA1"
[1219] "NDUFS4"
[1220] "PLIN3"
[1221] "MAGED2"
[1222] "MMAB"
[1223] "SIAE"
[1224] "ACLY"
[1225] "MRPL45"
[1226] "ATP5PD"
[1227] "TP53I11"
[1228] "YWHAH"
[1229] "GSR"
[1230] "PDK2"
[1231] "NRP1"
[1232] "NUP205"
[1233] "TALDO1"
[1234] "ADPRHL1"
[1235] "NEU1"
[1236] "RPL27A"
[1237] "PDCD6IP"
[1238] "ECE1"
[1239] "MYBBP1A"
[1240] "FMR1"
[1241] "PYROXD2"
[1242] "RCC1"
[1243] "CHID1"
[1244] "HDHD3"
[1245] "PLS3"
[1246] "AGRN"
[1247] "DDX21"
[1248] "MRPL47"
[1249] "ST13"
[1250] "SAFB2"
[1251] "PAFAH1B1"
[1252] "MYDGF"
[1253] "MTIF2"
[1254] "SMARCD3"
[1255] "CSTF3"
[1256] "EIF2S1"
[1257] "CPSF7"
[1258] "TBL2"
[1259] "PSIP1"
[1260] "PREB"
[1261] "VAMP2"
[1262] "PPP2CA"
[1263] "RO60"
[1264] "ACAD10"
[1265] "CTSZ"
[1266] "SMARCC1"
[1267] "MAPK1"
[1268] "GOLGA2"
[1269] "NDUFB6"
[1270] "COPG1"
[1271] "RPL21"
[1272] "PNKD"
[1273] "FAM120A"
[1274] "CYP2J2"
[1275] "SNAP23"
[1276] "HLA-A"
[1277] "RPS15"
[1278] "MCM5"
[1279] "GARS1"
[1280] "CSTF1"
[1281] "GRSF1"
[1282] "API5"
[1283] "MT-ND5"
[1284] "CSE1L"
[1285] "NECTIN2"
[1286] "MRPS12"
[1287] "TMEM205"
[1288] "UBTF"
[1289] "NDRG2"
[1290] "AHNAK2"
[1291] "DHCR7"
[1292] "ARPC2"
[1293] "TRIM54"
[1294] "SLC7A5"
[1295] "ATP6V0D1"
[1296] "RRAS2"
[1297] "YARS1"
[1298] "VCAN"
[1299] "ANXA11"
[1300] "SLC20A2"
[1301] "FHOD3"
[1302] "RPL14"
[1303] "PFKL"
[1304] "MRPS30"
[1305] "ABCC1"
[1306] "LYN"
[1307] "MTA1"
[1308] "FARSA"
[1309] "PYCR2"
[1310] "MBOAT7"
[1311] "DDX6"
[1312] "AKR7A2"
[1313] "AUH"
[1314] "CNTNAP1"
[1315] "TMEM109"
[1316] "XPNPEP3"
[1317] "NDUFAF4"
[1318] "U2SURP"
[1319] "ARMCX3"
[1320] "NDUFA7"
[1321] "PSMD8"
[1322] "MRPL14"
[1323] "FBN2"
[1324] "ABHD10"
[1325] "H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"
[1326] "SRP14"
[1327] "H1-10"
[1328] "RAB3A"
[1329] "BCL2L13"
[1330] "MARCHF5"
[1331] "EIF3F"
[1332] "COQ5"
[1333] "PSMB6"
[1334] "STAT3"
[1335] "MSRB2"
[1336] "SLC44A2"
[1337] "EPHX1"
[1338] "PPT1"
[1339] "UCHL1"
[1340] "ACOT13"
[1341] "ADAM10"
[1342] "ILVBL"
[1343] "RER1"
[1344] "SAP18"
[1345] "LYPLAL1"
[1346] "ARHGDIA"
[1347] "TFG"
[1348] "OXA1L"
[1349] "PSMB4"
[1350] "TP53I3"
[1351] "IPO7"
[1352] "RPS17"
[1353] "ISOC2"
[1354] "SLC35E1"
[1355] "FOXRED1"
[1356] "ANKFY1"
[1357] "MRPS35"
[1358] "NBAS"
[1359] "DNAJA2"
[1360] "PSAP"
[1361] "SIRT5"
[1362] "COL4A1"
[1363] "MRPS18A"
[1364] "KPNA2"
[1365] "RPL29"
[1366] "FXYD6"
[1367] "STX12"
[1368] "MTA2"
[1369] "CAMK2A"
[1370] "SSR4"
[1371] "EIF4H"
[1372] "CDC5L"
[1373] "TIMM21"
[1374] "CADM4"
[1375] "CKB"
[1376] "MRPL58"
[1377] "NAGLU"
[1378] "TIMM17B"
[1379] "TXNL1"
[1380] "CPS1"
[1381] "MRPS25"
[1382] "CPNE3"
[1383] "GYG1"
[1384] "USP5"
[1385] "NDUFB3"
[1386] "GOLIM4"
[1387] "RAB5B"
[1388] "MTX1"
[1389] "SMU1"
[1390] "EIF3H"
[1391] "MRPL22"
[1392] "ILK"
[1393] "CISD2"
[1394] "L2HGDH"
[1395] "PAICS"
[1396] "EIF5B"
[1397] "RPL28"
[1398] "HAGH"
[1399] "HIP1"
[1400] "MPC1"
[1401] "HRNR"
[1402] "RPA1"
[1403] "RPS24"
[1404] "LAMP1"
[1405] "TMED4"
[1406] "RPS27"
[1407] "PSMB2"
[1408] "ERAP1"
[1409] "ATIC"
[1410] "GPRIN3"
[1411] "SF3A2"
[1412] "CXADR"
[1413] "RPL35A"
[1414] "RAB5C"
[1415] "F11R"
[1416] "MCM3"
[1417] "SFXN4"
[1418] "DCAKD"
[1419] "CACYBP"
[1420] "MESD"
[1421] "EPS15L1"
[1422] "NOLC1"
[1423] "RPS19"
[1424] "EMC2"
[1425] "NCSTN"
[1426] "DAD1"
[1427] "PGD"
[1428] "RPL23"
[1429] "SNRPA"
[1430] "MYEF2"
[1431] "AKR1A1"
[1432] "STRN4"
[1433] "GBA2"
[1434] "YME1L1"
[1435] "PLRG1"
[1436] "AMT"
[1437] "PVR"
[1438] "YARS2"
[1439] "SERPINB6"
[1440] "HTATSF1"
[1441] "USP10"
[1442] "NCKAP1"
[1443] "PPOX"
[1444] "WDR18"
[1445] "MAN2B1"
[1446] "MCM4"
[1447] "DNAJC3"
[1448] "PRXL2A"
[1449] "SYNPO"
[1450] "SNRPD1"
[1451] "FASTKD2"
[1452] "SEC31A"
[1453] "FITM2"
[1454] "UQCRQ"
[1455] "SNRPA1"
[1456] "AGPAT1"
[1457] "EPHA4"
[1458] "DNAJA3"
[1459] "TMED7"
[1460] "SLC16A3"
[1461] "TIMMDC1"
[1462] "PLXNA1"
[1463] "RAB33B"
[1464] "NAMPT"
[1465] "EXOG"
[1466] "MYLK3"
[1467] "DDRGK1"
[1468] "SORT1"
[1469] "COMTD1"
[1470] "TARS1"
[1471] "PHF5A"
[1472] "DHRS4"
[1473] "ZFPL1"
[1474] "TMEM11"
[1475] "SART1"
[1476] "HINT1"
[1477] "PON2"
[1478] "ADAR"
[1479] "SURF4"
[1480] "GLIPR2"
[1481] "CRTAP"
[1482] "RPL34"
[1483] "EIF3M"
[1484] "STRBP"
[1485] "KANK2"
[1486] "MYPN"
[1487] "NDUFAF1"
[1488] "DYNC1I2"
[1489] "LACTB"
[1490] "EBP"
[1491] "F5"
[1492] "RPS23"
[1493] "CSTF2"
[1494] "SMPD1"
[1495] "SLC39A7"
[1496] "COX5B"
[1497] "COPS2"
[1498] "AK1"
[1499] "UBXN4"
[1500] "ERH"
[1501] "TM9SF3"
[1502] "RAE1"
[1503] "HAX1"
[1504] "TMEM33"
[1505] "P3H1"
[1506] "NIT2"
[1507] "EFNB1"
[1508] "SMARCA1"
[1509] "MRPS18B"
[1510] "PNN"
[1511] "WARS1"
[1512] "CAPN2"
[1513] "RPS27L"
[1514] "STXBP3"
[1515] "BPHL"
[1516] "CNBP"
[1517] "UQCRB"
[1518] "PIGK"
[1519] "GSK3B"
[1520] "SPCS3"
[1521] "EHD3"
[1522] "RAB13"
[1523] "LUC7L2"
[1524] "ROR1"
[1525] "EHD4"
[1526] "LMAN2L"
[1527] "DNAJB4"
[1528] "RBM26"
[1529] "WDR5"
[1530] "MAGT1"
[1531] "NDUFA6"
[1532] "TMED1"
[1533] "DPM1"
[1534] "HDGF"
[1535] "ANP32B"
[1536] "RTN2"
[1537] "NLRX1"
[1538] "NUBPL"
[1539] "LUC7L3"
[1540] "CYFIP2"
[1541] "TIMM23"
[1542] "ADD2"
[1543] "TMEM201"
[1544] "EPHB3"
[1545] "GALC"
[1546] "NRAS"
[1547] "ARPC4"
[1548] "ACSF3"
[1549] "PTGR3"
[1550] "MRPS7"
[1551] "MAIP1"
[1552] "COX20"
[1553] "ETHE1"
[1554] "ENDOD1"
[1555] "CBX3"
[1556] "BCKDK"
[1557] "GET3"
[1558] "TIAL1"
[1559] "PC"
[1560] "EMC3"
[1561] "TMLHE"
[1562] "NT5DC2"
[1563] "ZNF326"
[1564] "ABCF1"
[1565] "GLYR1"
[1566] "METAP1"
[1567] "HDAC1"
[1568] "MCM6"
[1569] "MECP2"
[1570] "MAP4K4"
[1571] "VPS13A"
[1572] "FKBP2"
[1573] "TEX10"
[1574] "SLC25A46"
[1575] "HDGFL3"
[1576] "M6PR"
[1577] "EDC4"
[1578] "RNMT"
[1579] "CARS2"
[1580] "ADCY6"
[1581] "EIF3G"
[1582] "SYNGR2"
[1583] "ELOC"
[1584] "DLG1"
[1585] "NAV1"
[1586] "LMF2"
[1587] "NCBP1"
[1588] "ATPAF1"
[1589] "RUSF1"
[1590] "MT-CO1"
[1591] "GBA1"
[1592] "RBM15"
[1593] "MT-ATP6"
[1594] "FKBP4"
[1595] "C8orf82"
[1596] "MRPL46"
[1597] "DHTKD1"
[1598] "VPS45"
[1599] "TRA2B"
[1600] "WDR82"
[1601] "NAGA"
[1602] "RANGAP1"
[1603] "ROMO1"
[1604] "PLXNA2"
[1605] "RAB5A"
[1606] "DDX50"
[1607] "GRN"
[1608] "DUT"
[1609] "MT-ND1"
[1610] "SCAMP2"
[1611] "RBM3"
[1612] "MMP15"
[1613] "ERGIC3"
[1614] "BAX"
[1615] "LAMTOR3"
[1616] "FYN"
[1617] "MRPS17"
[1618] "FILIP1"
[1619] "SUGT1"
[1620] "SEPTIN6"
[1621] "EARS2"
[1622] "FAM98B"
[1623] "ISYNA1"
[1624] "STOM"
[1625] "LMOD1"
[1626] "HSPB8"
[1627] "SEC62"
[1628] "THBS1"
[1629] "LLGL1"
[1630] "PURB"
[1631] "NDUFB11"
[1632] "PRPF40A"
[1633] "MTFR1L"
[1634] "TMCO1"
[1635] "CHP1"
[1636] "PURA"
[1637] "GPS1"
[1638] "DDT"
[1639] "ABCB8"
[1640] "PPA1"
[1641] "PARVA"
[1642] "SPTLC1"
[1643] "PSMB3"
[1644] "ALG2"
[1645] "NDUFA5"
[1646] "ADAMTSL4"
[1647] "TIMM29"
[1648] "SEC11A"
[1649] "OXSM"
[1650] "SDR39U1"
[1651] "BDH1"
[1652] "YAP1"
[1653] "BLMH"
[1654] "CTBP1"
[1655] "AIMP2"
[1656] "ESYT2"
[1657] "EIF3J"
[1658] "PLXNA4"
[1659] "HCN4"
[1660] "SRP72"
[1661] "HDGFL2"
[1662] "SEC61B"
[1663] "NDUFB10"
[1664] "FAM210A"
[1665] "SNRPB"
[1666] "EMC7"
[1667] "COQ8A"
[1668] "HEBP1"
[1669] "HSP90AB4P"
[1670] "ISOC1"
[1671] "RPS25"
[1672] "TMEM214"
[1673] "NDUFAF7"
[1674] "MIA3"
[1675] "ENAH"
[1676] "CYRIB"
[1677] "TMEM14C"
[1678] "SLC25A22"
[1679] "PNPLA8"
[1680] "NUCB1"
[1681] "MT-ND4"
[1682] "VASP"
[1683] "ARID1A"
[1684] "PRPS1"
[1685] "PCMT1"
[1686] "SMARCE1"
[1687] "CPSF1"
[1688] "BCKDHB"
[1689] "NDUFB5"
[1690] "FBLIM1"
[1691] "GPAA1"
[1692] "SIRT3"
[1693] "COA1"
[1694] "EIF3K"
[1695] "TFAM"
[1696] "UBE4A"
[1697] "PTRH2"
[1698] "GCAT"
[1699] "CYFIP1"
[1700] "SRSF5"
[1701] "MTPAP"
[1702] "UPF1"
[1703] "SQOR"
[1704] "HRAS"
[1705] "CNPY3"
[1706] "APEH"
[1707] "RAD50"
[1708] "RPS26"
[1709] "SPCS1"
[1710] "GNPAT"
[1711] "SYPL1"
[1712] "EIF2S2"
[1713] "SRP68"
[1714] "HTRA1"
[1715] "PPM1G"
[1716] "PTTG1IP"
[1717] "CDK9"
[1718] "FAM162A"
[1719] "NDUFAF3"
[1720] "RPLP2"
[1721] "RRP12"
[1722] "SMARCA5"
[1723] "NUP35"
[1724] "ZMPSTE24"
[1725] "IMPA1"
[1726] "MANF"
[1727] "ARG2"
[1728] "TMEM41B"
[1729] "H6PD"
[1730] "TMX1"
[1731] "PTPRM"
[1732] "AHSG"
[1733] "PPP1R12C"
[1734] "MRPL48"
[1735] "INPP5A"
[1736] "SOD3"
[1737] "ZRANB2"
[1738] "FUCA1"
[1739] "OSBPL8"
[1740] "HAPLN1"
[1741] "NOP2"
[1742] "SNRPB2"
[1743] "COQ3"
[1744] "TRIM63"
[1745] "SLC27A4"
[1746] "RPL32"
[1747] "SRSF11"
[1748] "ZW10"
[1749] "GNAO1"
[1750] "SMARCB1"
[1751] "APLP2"
[1752] "ERGIC2"
[1753] "PTPRK"
[1754] "MACROD1"
[1755] "PLOD2"
[1756] "AP3M1"
[1757] "SH3GLB1"
[1758] "SLC25A21"
[1759] "SORD"
[1760] "RBM12"
[1761] "MRE11"
[1762] "GSTO1"
[1763] "TMEM70"
[1764] "UBQLN1"
[1765] "HTRA2"
[1766] "PREP"
[1767] "ACO1"
[1768] "SAR1A"
[1769] "UFSP2"
[1770] "NME3"
[1771] "SCO2"
[1772] "CDS2"
[1773] "MRPL27"
[1774] "ATP2C1"
[1775] "TMEM256"
[1776] "GNA13"
[1777] "MPST"
[1778] "DOCK7"
[1779] "DCTN4"
[1780] "HARS1"
[1781] "PROS1"
[1782] "LBR"
[1783] "SNU13"
[1784] "HGS"
[1785] "ITGA1"
[1786] "NPLOC4"
[1787] "GAPDHS"
[1788] "CD44"
[1789] "EMC8"
[1790] "ADRM1"
[1791] "CNN3"
[1792] "LCLAT1"
[1793] "ARL1"
[1794] "FASTKD1"
[1795] "LETMD1"
[1796] "CELF1"
[1797] "RPL36AL"
[1798] "PTGES3"
[1799] "POFUT2"
[1800] "DAAM1"
[1801] "LEMD3"
[1802] "CAVIN4"
[1803] "GCSH"
[1804] "DIPK2A"
[1805] "RAP2C"
[1806] "MAGOHB"
[1807] "NUP98"
[1808] "RPL31"
[1809] "COL6A1"
[1810] "NDUFB8"
[1811] "BCAP29"
[1812] "SDHC"
[1813] "PRKRA"
[1814] "TRA2A"
[1815] "CPSF2"
[1816] "COX6C"
[1817] "CES1"
[1818] "NUP133"
[1819] "CD99L2"
[1820] "NDUFA2"
[1821] "AP3B1"
[1822] "TAMM41"
[1823] "B3GAT3"
[1824] "PPIC"
[1825] "ARSA"
[1826] "MRPS15"
[1827] "ATP5IF1"
[1828] "COPS5"
[1829] "MRPL20"
[1830] "MRPS14"
[1831] "NXF1"
[1832] "COPS4"
[1833] "MICOS10"
[1834] "EPM2AIP1"
[1835] "YTHDC1"
[1836] "NIBAN1"
[1837] "EPB41L5"
[1838] "LANCL2"
[1839] "TXNRD1"
[1840] "SORBS1"
[1841] "OAT"
[1842] "TMEM38B"
[1843] "COQ6"
[1844] "BRI3BP"
[1845] "EMC4"
[1846] "DDAH2"
[1847] "WBP11"
[1848] "OVCA2"
[1849] "MRPS16"
[1850] "COL3A1"
[1851] "DNM1L"
[1852] "ECHDC1"
[1853] "GATB"
[1854] "TIA1"
[1855] "SLC30A1"
[1856] "SPNS1"
[1857] "ATP11A"
[1858] "TMEM40"
[1859] "SAR1B"
[1860] "FNDC3B"
[1861] "ACSS3"
[1862] "EPB41"
[1863] "UBQLN2"
[1864] "BTN2A1"
[1865] "SLC7A6"
[1866] "SRRM1"
[1867] "RABL3"
[1868] "EXOC4"
[1869] "COQ8B"
[1870] "PLAA"
[1871] "PACS1"
[1872] "PHPT1"
[1873] "NUP88"
[1874] "MTOR"
[1875] "DTYMK"
[1876] "EIF4B"
[1877] "RMDN1"
[1878] "DMAC2L"
[1879] "CLCN7"
[1880] "RBM10"
[1881] "MASP1"
[1882] "SNRNP40"
[1883] "SEC23IP"
[1884] "ARPC1B"
[1885] "GALNS"
[1886] "USE1"
[1887] "GPX8"
[1888] "FIP1L1"
[1889] "ITPRIP"
[1890] "SEH1L"
[1891] "H3-3A; H3-3B"
[1892] "RPL36A"
[1893] "SLC35B2"
[1894] "SLC25A15"
[1895] "PAK2"
[1896] "MRPL10"
[1897] "ZNF638"
[1898] "PSMD14"
[1899] "RANBP6"
[1900] "LARP7"
[1901] "MICAL3"
[1902] "ERLIN1"
[1903] "DGUOK"
[1904] "NUDT9"
[1905] "AP1G1"
[1906] "EFR3A"
[1907] "CD151"
[1908] "ATP6V1H"
[1909] "ZC3H14"
[1910] "FBLN1"
[1911] "COA7"
[1912] "ETF1"
[1913] "STAU1"
[1914] "KPNA6"
[1915] "ARMC1"
[1916] "NANS"
[1917] "RBPMS2"
[1918] "PALS2"
[1919] "TMEM132A"
[1920] "RPS21"
[1921] "UBE2M"
[1922] "AKAP8L"
[1923] "SEPTIN10"
[1924] "RABAC1"
[1925] "DDX24"
[1926] "STX4"
[1927] "KYAT3"
[1928] "PPP4C"
[1929] "TUSC3"
[1930] "MRPS36"
[1931] "POGLUT1"
[1932] "GPAT3"
[1933] "COPZ1"
[1934] "POMGNT1"
[1935] "ERLEC1"
[1936] "PCNA"
[1937] "HSPA13"
[1938] "MGST2"
[1939] "PPFIBP1"
[1940] "PLCD3"
[1941] "MARK2"
[1942] "DHODH"
[1943] "TPT1"
[1944] "DGAT1"
[1945] "ATPAF2"
[1946] "SUPT5H"
[1947] "MGME1"
[1948] "ATP6AP1"
[1949] "PRMT5"
[1950] "MCU"
[1951] "NARS2"
[1952] "CUL4B"
[1953] "NUP153"
[1954] "CNPY2"
[1955] "SNRPD2"
[1956] "EEF1B2"
[1957] "MTFP1"
[1958] "UQCR10"
[1959] "RPL37A"
[1960] "APOBEC2"
[1961] "WLS"
[1962] "ACAD11"
[1963] "PPTC7"
[1964] "TBL1XR1"
[1965] "NUDT19"
[1966] "CENPV"
[1967] "KIAA2013"
[1968] "MCM7"
[1969] "ATXN2L"
[1970] "EIF6"
[1971] "KPNA4"
[1972] "YIF1B"
[1973] "TEX264"
[1974] "LAMA2"
[1975] "CALM3"
[1976] "CD63"
[1977] "ITSN1"
[1978] "CUL3"
[1979] "SF3B4"
[1980] "MVP"
[1981] "UFD1"
[1982] "PAFAH1B3"
[1983] "RYR3"
[1984] "CHCHD6"
[1985] "RBM24"
[1986] "ELOVL1"
[1987] "ISCA2"
[1988] "RRAGA"
[1989] "MRPS24"
[1990] "CAPNS1"
[1991] "COPS6"
[1992] "EPPK1"
[1993] "IK"
[1994] "NCOA5"
[1995] "LIN7A"
[1996] "VKORC1L1"
[1997] "GK"
[1998] "DNAJC5"
[1999] "VPS26A"
[2000] "GJA1"
[2001] "ODR4"
[2002] "MRPL50"
[2003] "OLA1"
[2004] "UBE2V1"
[2005] "CSNK2B"
[2006] "FUCA2"
[2007] "KPNA3"
[2008] "GLRX5"
[2009] "USP39"
[2010] "NCEH1"
[2011] "CDK11B"
[2012] "PML"
[2013] "MRPL28"
[2014] "ATP13A3"
[2015] "VLDLR"
[2016] "SRPK2"
[2017] "CCDC51"
[2018] "SLC30A5"
[2019] "NUP43"
[2020] "BZW2"
[2021] "LYPLA1"
[2022] "MTX3"
[2023] "LAS1L"
[2024] "COL4A2"
[2025] "TMX4"
[2026] "ROR2"
[2027] "CUL4A"
[2028] "PIP4P2"
[2029] "EMC6"
[2030] "UBE2N"
[2031] "DMAC1"
[2032] "DCAF8"
[2033] "SYMPK"
[2034] "TRIP12"
[2035] "DST"
[2036] "COPE"
[2037] "GBF1"
[2038] "LANCL1"
[2039] "SORBS3"
[2040] "RHOB"
[2041] "ATP1B2"
[2042] "NMT1"
[2043] "OGT"
[2044] "SLC30A6"
[2045] "CLPTM1L"
[2046] "DRG1"
[2047] "CHERP"
[2048] "RANBP3"
[2049] "MRPL32"
[2050] "MYO1B"
[2051] "MT-ND2"
[2052] "DNAJB6"
[2053] "IKBIP"
[2054] "GDE1"
[2055] "PQBP1"
[2056] "ACOT11"
[2057] "PRPF3"
[2058] "TMEM106B"
[2059] "COPG2"
[2060] "TXNDC17"
[2061] "SMC1A"
[2062] "SLC29A1"
[2063] "HS2ST1"
[2064] "MRAS"
[2065] "VTN"
[2066] "IDE"
[2067] "MRPL11"
[2068] "EPDR1"
[2069] "MARS2"
[2070] "NSUN2"
[2071] "NUP160"
[2072] "HMGB3"
[2073] "MPDU1"
[2074] "NAT14"
[2075] "MMGT1"
[2076] "DBNL"
[2077] "SNX2"
[2078] "UCHL5"
[2079] "PARS2"
[2080] "POGZ"
[2081] "PRKAA1"
[2082] "DECR2"
[2083] "RBX1"
[2084] "LRRN4"
[2085] "ANTXR2"
[2086] "NUCKS1"
[2087] "CBR1"
[2088] "GART"
[2089] "ANXA7"
[2090] "ESD"
[2091] "SURF1"
[2092] "MGAT2"
[2093] "AP3D1"
[2094] "EMILIN2"
[2095] "PSME3"
[2096] "ACOT8"
[2097] "FAM136A"
[2098] "SIGMAR1"
[2099] "LIN7C"
[2100] "FADS1"
[2101] "MBNL1"
[2102] "SCN5A"
[2103] "COPS8"
[2104] "TNNT1"
[2105] "TIMM22"
[2106] "RPS10"
[2107] "MFF"
[2108] "ZNF207"
[2109] "PXN"
[2110] "PEX14"
[2111] "SNX27"
[2112] "MAP1LC3B"
[2113] "GUSB"
[2114] "TMED2"
[2115] "CHTOP"
[2116] "KDM1A"
[2117] "GSPT1"
[2118] "PARL"
[2119] "DNAJB2"
[2120] "TXNDC12"
[2121] "TOP1MT"
[2122] "XPNPEP1"
[2123] "RPL36"
[2124] "NUP214"
[2125] "FIS1"
[2126] "ATP5ME"
[2127] "GTPBP6"
[2128] "GLO1"
[2129] "PI4KA"
[2130] "MRPL17"
[2131] "DHCR24"
[2132] "NDUFA4"
[2133] "EIF5"
[2134] "TMEM30A"
[2135] "ADNP"
[2136] "TMEM115"
[2137] "MRPL12"
[2138] "STX8"
[2139] "TIMP3"
[2140] "CBX5"
[2141] "DHRS7B"
[2142] "PABPC5"
[2143] "ATG9A"
[2144] "FDFT1"
[2145] "NDUFS5"
[2146] "SLC30A9"
[2147] "ALPK3"
[2148] "FASTKD5"
[2149] "EIF2A"
[2150] "NRAP"
[2151] "SPR"
[2152] "CDH11"
[2153] "SLC35F6"
[2154] "NEK7"
[2155] "ACBD5"
[2156] "CNN2"
[2157] "PPP5C"
[2158] "MFN1"
[2159] "POLR2B"
[2160] "SELENOI"
[2161] "BPNT2"
[2162] "ALG9"
[2163] "BAG3"
[2164] "SLC2A4"
[2165] "SRSF10"
[2166] "PLS1"
[2167] "MRPL23"
[2168] "PCYOX1L"
[2169] "HINT2"
[2170] "ITGA6"
[2171] "ATP6AP2"
[2172] "BAG6"
[2173] "SYNE1"
[2174] "NAT10"
[2175] "UBA3"
[2176] "KDELR1"
[2177] "LAMP2"
[2178] "MTREX"
[2179] "CTBP2"
[2180] "GPX4"
[2181] "GOSR2"
[2182] "USP9X"
[2183] "CIAPIN1"
[2184] "VKORC1"
[2185] "NOC2L"
[2186] "TM7SF2"
[2187] "AAAS"
[2188] "TOMM20"
[2189] "ADAM9"
[2190] "CPSF3"
[2191] "RP2"
[2192] "NUDT5"
[2193] "COMT"
[2194] "TMED5"
[2195] "MRPS28"
[2196] "SDF2L1"
[2197] "MPRIP"
[2198] "SLC1A4"
[2199] "COX7A2L"
[2200] "MTHFS"
[2201] "VTI1B"
[2202] "GGCX"
[2203] "RIDA"
[2204] "COX15"
[2205] "TRMU"
[2206] "ANO6"
[2207] "CPNE5"
[2208] "CLDN6"
[2209] "TMEM259"
[2210] "NUP58"
[2211] "SMS"
[2212] "PDLIM4"
[2213] "CRELD2"
[2214] "NDUFB7"
[2215] "ELOB"
[2216] "CDIPT"
[2217] "IGF1R"
[2218] "MAP2K1"
[2219] "UBR4"
[2220] "WARS2"
[2221] "SSR3"
[2222] "PRRC2A"
[2223] "THEM6"
[2224] "PRKAA2"
[2225] "TMEM192"
[2226] "RCC2"
[2227] "NIT1"
[2228] "TES"
[2229] "NRM"
[2230] "DPP3"
[2231] "CD47"
[2232] "SRP54"
[2233] "PPP2R5A"
[2234] "AGFG1"
[2235] "LDHAL6B"
[2236] "RRAGC"
[2237] "RAB23"
[2238] "NUP54"
[2239] "ABI1"
[2240] "REXO2"
[2241] "ELMOD2"
[2242] "STRA6"
[2243] "TMEM167A"
[2244] "PHLDB2"
[2245] "SLC38A10"
[2246] "SARS1"
[2247] "GPD1L"
[2248] "SYNE2"
[2249] "MECR"
[2250] "AARS1"
[2251] "MID1"
[2252] "UBE2J1"
[2253] "CNDP2"
[2254] "TOR1AIP2"
[2255] "SLC7A1"
[2256] "PHF6"
[2257] "SELENOT"
[2258] "MSMO1"
[2259] "MCM2"
[2260] "SNRPD3"
[2261] "PIN1"
[2262] "UACA"
[2263] "LDLR"
[2264] "CDK12"
[2265] "CAND2"
[2266] "PAFAH1B2"
[2267] "SLC22A18"
[2268] "FDPS"
[2269] "CTNNBL1"
[2270] "TJP2"
[2271] "CPT1B"
[2272] "TRNT1"
[2273] "SIL1"
[2274] "KRT73"
[2275] "PLPBP"
[2276] "FSTL1"
[2277] "PRAF2"
[2278] "IDUA"
[2279] "ADHFE1"
[2280] "HLA-C"
[2281] "ATP5F1EP2"
[2282] "PALM"
[2283] "MPV17L2"
[2284] "RBMS1"
[2285] "SLC16A7"
[2286] "SON"
[2287] "SEC24B"
[2288] "TAX1BP3"
[2289] "LTA4H"
[2290] "THOC2"
[2291] "VPS29"
[2292] "PIP4K2A"
[2293] "ITGB1BP2"
[2294] "DNAJB1"
[2295] "GMPS"
[2296] "STK39"
[2297] "PFN2"
[2298] "RAB24"
[2299] "VCAM1"
[2300] "SNX9"
[2301] "CHPF"
[2302] "NFU1"
[2303] "SCYL1"
[2304] "ECPAS"
[2305] "ALG1"
[2306] "NOL9"
[2307] "EXOC8"
[2308] "TM9SF1"
[2309] "AGPAT3"
[2310] "KLHL41"
[2311] "BTF3L4"
[2312] "ICMT"
[2313] "JAM3"
[2314] "ITSN2"
[2315] "SCAF4"
[2316] "TMEM120A"
[2317] "DIABLO"
[2318] "PKN2"
[2319] "CUX1"
[2320] "PRORP"
[2321] "PI4K2A"
[2322] "IQGAP1"
[2323] "GTPBP10"
[2324] "NDUFAF5"
[2325] "IRF2BPL"
[2326] "STX18"
[2327] "CTPS2"
[2328] "XPO7"
[2329] "NMNAT1"
[2330] "PRRC1"
[2331] "STK26"
[2332] "TAPT1"
[2333] "MUL1"
[2334] "TSN"
[2335] "AKAP12"
[2336] "PPL"
[2337] "RINT1"
[2338] "GATAD2A"
[2339] "SLC39A14"
[2340] "UBE2L3"
[2341] "ITGB3"
[2342] "ERAL1"
[2343] "GLA"
[2344] "RAB34"
[2345] "DDX47"
[2346] "MCAT"
[2347] "ARL2"
[2348] "EIF1AX"
[2349] "NAE1"
[2350] "LACTB2"
[2351] "METTL15"
[2352] "SSR1"
[2353] "ATP6V1E1"
[2354] "LPCAT3"
[2355] "YIPF5"
[2356] "PPIG"
[2357] "RPS29"
[2358] "THNSL1"
[2359] "QKI"
[2360] "TAP1"
[2361] "ATL2"
[2362] "UNG"
[2363] "SGTA"
[2364] "NUDC"
[2365] "BAG2"
[2366] "MAT2A"
[2367] "GGT1"
[2368] "DYNLL1"
[2369] "TMEM126B"
[2370] "EIF2B3"
[2371] "PDXP"
[2372] "RTRAF"
[2373] "XXYLT1"
[2374] "MSRA"
[2375] "GOSR1"
[2376] "MMAA"
[2377] "CDH13"
[2378] "RETREG3"
[2379] "NLN"
[2380] "NDUFC2"
[2381] "STARD3NL"
[2382] "PPP6C"
[2383] "MAP2K2"
[2384] "PPP2R5E"
[2385] "CDC37"
[2386] "FADS2"
[2387] "UBE3A"
[2388] "GLRX3"
[2389] "RRAD"
[2390] "STRIP2"
[2391] "HINT3"
[2392] "RNPS1"
[2393] "STX16"
[2394] "MOB4"
[2395] "SHROOM2"
[2396] "RMDN3"
[2397] "TOM1L2"
[2398] "TSPAN18"
[2399] "ERG28"
[2400] "NDUFA3"
[2401] "HMGN2"
[2402] "MAN1B1"
[2403] "ANXA4"
[2404] "SLC4A1AP"
[2405] "STIM1"
[2406] "MIF"
[2407] "OCIAD2"
[2408] "MAGI1"
[2409] "TAPBP"
[2410] "DMAC2"
[2411] "QRSL1"
[2412] "USP14"
[2413] "MACROH2A2"
[2414] "FXN"
[2415] "DUSP3"
[2416] "CD46"
[2417] "Creb1; CREB1; LOC101356881"
[2418] "TLCD4"
[2419] "SUPT6H"
[2420] "PACSIN2"
[2421] "NDUFB1"
[2422] "MYO1D"
[2423] "IST1"
[2424] "YIF1A"
[2425] "RBMXL3"
[2426] "TSG101"
[2427] "LTF"
[2428] "RPP30"
[2429] "RRP9"
[2430] "TFB1M"
[2431] "ATP6V1C1"
[2432] "LGMN"
[2433] "MT-CYB"
[2434] "CUL5"
[2435] "RARS2"
[2436] "ARFGAP2"
[2437] "CLCN5"
[2438] "JAGN1"
[2439] "CDC73"
[2440] "SEPTIN5"
[2441] "EPB41L2"
[2442] "MRPS26"
[2443] "PITPNM1"
[2444] "SPARC"
[2445] "JPH1"
[2446] "PIP5K1A"
[2447] "ASCC3"
[2448] "ADSL"
[2449] "METAP2"
[2450] "NME4"
[2451] "KLC1"
[2452] "RPA2"
[2453] "RBM8A"
[2454] "NUDT6"
[2455] "KIRREL1"
[2456] "EHD2"
[2457] "CLCN3"
[2458] "NTPCR"
[2459] "DDX18"
[2460] "FAM3C"
[2461] "VPS18"
[2462] "PRPF4B"
[2463] "RMND1"
[2464] "VEZT"
[2465] "MBLAC2"
[2466] "EDNRA"
[2467] "CD55"
[2468] "RPS28"
[2469] "ZC3H18"
[2470] "PCBD1"
[2471] "ALG11"
[2472] "STMN1"
[2473] "TRAM1"
[2474] "MRPL40"
[2475] "GRB2"
[2476] "ARMC8"
[2477] "AAK1"
[2478] "SYNGR1"
[2479] "EDIL3"
[2480] "AP2S1"
[2481] "RAB9A"
[2482] "DDAH1"
[2483] "PPP2R5D"
[2484] "NUCB2"
[2485] "OSTC"
[2486] "MRPL41"
[2487] "RBFOX1"
[2488] "STK11IP"
[2489] "GOLGA7"
[2490] "SBDS"
[2491] "GLOD4"
[2492] "MFSD10"
[2493] "TMUB1"
[2494] "LPGAT1"
[2495] "GNL3"
[2496] "POGLUT3"
[2497] "GRPEL1"
[2498] "HNRNPLL"
[2499] "RCN2"
[2500] "CACHD1"
[2501] "DKK3"
[2502] "SUMF1"
[2503] "THOC6"
[2504] "STXBP1"
[2505] "UBE2D3"
[2506] "CERS2"
[2507] "ELAC2"
[2508] "TNIK"
[2509] "CAST"
[2510] "NPM3"
[2511] "TOMM22"
[2512] "BLVRB"
[2513] "NDUFB4"
[2514] "YIPF4"
[2515] "SFT2D3"
[2516] "RSU1"
[2517] "TWF2"
[2518] "SMAD2"
[2519] "EXOC1"
[2520] "ACP1"
[2521] "CUL2"
[2522] "ABCE1"
[2523] "GORASP1"
[2524] "FNDC3A"
[2525] "VAMP7"
[2526] "CCDC134"
[2527] "DDX19B"
[2528] "SPHKAP"
[2529] "YIPF3"
[2530] "POLR2A"
[2531] "PDE12"
[2532] "SUB1"
[2533] "DDX28"
[2534] "CHAMP1"
[2535] "SUMF2"
[2536] "SDF2"
[2537] "PPP4R3A"
[2538] "AKAP13"
[2539] "SCAF8"
[2540] "A2M"
[2541] "FITM1"
[2542] "NUP107"
[2543] "TAGLN2"
[2544] "PRPF31"
[2545] "FLAD1"
[2546] "DCAF7"
[2547] "SPTLC2"
[2548] "ATXN10"
[2549] "PIP4P1"
[2550] "SLC25A19"
[2551] "ITGA11"
[2552] "ITIH2"
[2553] "AP1M1"
[2554] "SLC12A2"
[2555] "NLRP13"
[2556] "FN3K"
[2557] "CASZ1"
[2558] "RAB9B"
[2559] "CUL1"
[2560] "NUDT16L1"
[2561] "GOLGA3"
[2562] "COX7A2"
[2563] "HPRT1"
[2564] "AKAP1"
[2565] "SLC1A5"
[2566] "LIPT2"
[2567] "GIT2"
[2568] "APP"
[2569] "CMPK1"
[2570] "COX11"
[2571] "TMEM143"
[2572] "UBA2"
[2573] "CLCC1"
[2574] "GPAT4"
[2575] "PCID2"
[2576] "DDX27"
[2577] "PDCD6"
[2578] "ATP6V1D"
[2579] "NSUN4"
[2580] "OPA3"
[2581] "SERPINC1"
[2582] "EEF1E1"
[2583] "DLG3"
[2584] "PCYT1A"
[2585] "CTSL"
[2586] "GFER"
[2587] "ALG6"
[2588] "BAIAP2"
[2589] "CSNK2A2"
[2590] "PIEZO1"
[2591] "MCEE"
[2592] "TRIM24"
[2593] "DLG2"
[2594] "CPNE1"
[2595] "HACD2"
[2596] "PRPSAP2"
[2597] "FZD2"
[2598] "LTBP1"
[2599] "NUTF2"
[2600] "RAB31"
[2601] "NAXD"
[2602] "NDUFAF2"
[2603] "GIT1"
[2604] "WWC3"
[2605] "OGFOD3"
[2606] "HHATL"
[2607] "S1PR1"
[2608] "DSC1"
[2609] "OTUB1"
[2610] "CERS6"
[2611] "FABP5"
[2612] "HOMER3"
[2613] "SELENOH"
[2614] "AHSA1"
[2615] "USP15"
[2616] "VMP1"
[2617] "BZW1"
[2618] "RBM12B"
[2619] "EXOSC3"
[2620] "PEX3"
[2621] "ANTXR1"
[2622] "EXOSC6"
[2623] "USP11"
[2624] "SLC25A14"
[2625] "ZC3H4"
[2626] "CWC15"
[2627] "DPY19L1"
[2628] "PRKAG2"
[2629] "SLC35A4"
[2630] "MAP1A"
[2631] "MRM1"
[2632] "IMPDH2"
[2633] "THOC1"
[2634] "BPNT1"
[2635] "PNPLA6"
[2636] "COPS3"
[2637] "CD99"
[2638] "YY1"
[2639] "CTNND2"
[2640] "SLC38A7"
[2641] "GPX7"
[2642] "ARMC10"
[2643] "NAPG"
[2644] "EXOC2"
[2645] "SDHD"
[2646] "CTR9"
[2647] "SNX6"
[2648] "DPF1"
[2649] "SNX18"
[2650] "REPS1"
[2651] "DERL1"
[2652] "CASP3"
[2653] "EXOSC7"
[2654] "MRPL30"
[2655] "D2HGDH"
[2656] "GALNT1"
[2657] "RBM17"
[2658] "RECQL"
[2659] "NUDT8"
[2660] "EMC10"
[2661] "POMK"
[2662] "LARP1"
[2663] "PEX16"
[2664] "CPNE4"
[2665] "LSM8"
[2666] "OXNAD1"
[2667] "YTHDF3"
[2668] "ARSD"
[2669] "PIGU"
[2670] "LSM2"
[2671] "CACNB2"
[2672] "PEX13"
[2673] "MTG1"
[2674] "SNTB2"
[2675] "SLC5A6"
[2676] "LAMTOR4"
[2677] "SCPEP1"
[2678] "DNAJC16"
[2679] "NPC1"
[2680] "SDK2"
[2681] "VPS16"
[2682] "MRRF"
[2683] "RRP8"
[2684] "DEGS1"
[2685] "SNX3"
[2686] "PTPMT1"
[2687] "STAU2"
[2688] "PIP5K1C"
[2689] "CD276"
[2690] "AGO2"
[2691] "VASN"
[2692] "SRP9"
[2693] "FHL3"
[2694] "NDRG3"
[2695] "TMEM160"
[2696] "RAB27A"
[2697] "MLST8"
[2698] "TTC7B"
[2699] "PDIA5"
[2700] "TEX2"
[2701] "ORMDL3"
[2702] "MAOB"
[2703] "WBP2"
[2704] "NDUFAF6"
[2705] "SKIC8"
[2706] "ACP6"
[2707] "SPRYD7"
[2708] "WASF2"
[2709] "BCL2L1"
[2710] "LARP4"
[2711] "F2"
[2712] "MRPL18"
[2713] "ARFGAP1"
[2714] "STARD7"
[2715] "GDPD1"
[2716] "NUP85"
[2717] "ZC3H11A"
[2718] "INTS3"
[2719] "EXOSC10"
[2720] "PSME1"
[2721] "POLG"
[2722] "VAC14"
[2723] "WDFY1"
[2724] "SMNDC1"
[2725] "TMEM177"
[2726] "GIPC1"
[2727] "MBTPS2"
[2728] "ROCK2"
[2729] "CTPS1"
[2730] "SEL1L"
[2731] "NUP37"
[2732] "PNKP"
[2733] "ABCF2"
[2734] "AGPAT4"
[2735] "RTCA"
[2736] "MTUS2"
[2737] "LLGL2"
[2738] "SH3BP4"
[2739] "POGLUT2"
[2740] "CPD"
[2741] "MAP1S"
[2742] "PRRC2C"
[2743] "WDR77"
[2744] "YIPF6"
[2745] "SLC26A2"
[2746] "ACSS2"
[2747] "FAM177A1"
[2748] "SMC3"
[2749] "TPRG1L"
[2750] "ALG12"
[2751] "MRS2"
[2752] "CLASP1"
[2753] "SMPD4"
[2754] "AUP1"
[2755] "TMEM50A"
[2756] "UQCC1"
[2757] "CLYBL"
[2758] "AHCYL2"
[2759] "DHRS7"
[2760] "CLINT1"
[2761] "MAP3K20"
[2762] "ATP8B3"
[2763] "ATP11B"
[2764] "ARHGEF7"
[2765] "AQR"
[2766] "GADD45GIP1"
[2767] "PDS5A"
[2768] "TOMM40L"
[2769] "ZNF512B"
[2770] "OSBP"
[2771] "TWF1"
[2772] "PPIH"
[2773] "MDK"
[2774] "PTPRD"
[2775] "MRPL21"
[2776] "SLC39A6"
[2777] "ARGLU1"
[2778] "EXTL3"
[2779] "RIOX1"
[2780] "TMEM97"
[2781] "GSS"
[2782] "C1orf198"
[2783] "EIF2B1"
[2784] "LRRC10"
[2785] "TSPO"
[2786] "SCRN1"
[2787] "MYO7B"
[2788] "AIDA"
[2789] "GIGYF2"
[2790] "PNPLA4"
[2791] "CCN2"
[2792] "NFIC"
[2793] "SLC38A1"
[2794] "CEPT1"
[2795] "MYO5C"
[2796] "MAN1C1"
[2797] "COQ10B"
[2798] "PRNP"
[2799] "BORCS6"
[2800] "EXD2"
[2801] "POP1"
[2802] "HAT1"
[2803] "EXOSC2"
[2804] "PLD1"
[2805] "GPC6"
[2806] "SPAG9"
[2807] "YKT6"
[2808] "SDC4"
[2809] "ROCK1"
[2810] "PUDP"
[2811] "EIF2B5"
[2812] "COASY"
[2813] "HEPH"
[2814] "DPF3"
[2815] "LRATD2"
[2816] "DYNC1LI2"
[2817] "NAA15"
[2818] "KPRP"
[2819] "LIMS1"
[2820] "TCHH"
[2821] "RAD23A"
[2822] "CLPP"
[2823] "MRM3"
[2824] "WDR44"
[2825] "CARD19"
[2826] "MSRB3"
[2827] "STAT1"
[2828] "TOLLIP"
[2829] "DHRS13"
[2830] "PTPRS"
[2831] "TECRL"
[2832] "PAIP1"
[2833] "MOXD1"
[2834] "PPAN"
[2835] "EXOC6B"
[2836] "RPS6KA3"
[2837] "SIPA1L3"
[2838] "MAT2B"
[2839] "PDCD10"
[2840] "PITPNB"
[2841] "TMEM38A"
[2842] "AURKAIP1"
[2843] "TMEM63B"
[2844] "SKP1"
[2845] "CYSTM1"
[2846] "HACD1"
[2847] "ADPGK"
[2848] "SLC31A1"
[2849] "GGT7"
[2850] "CSNK1E"
[2851] "ATXN2"
[2852] "IL1RAP"
[2853] "PDF"
[2854] "CYBC1"
[2855] "FUNDC1"
[2856] "ANKLE2"
[2857] "AKAP9"
[2858] "FAM169A"
[2859] "COX18"
[2860] "AMPD2"
[2861] "WDR43"
[2862] "NUP188"
[2863] "KIF2A"
[2864] "BDH2"
[2865] "SCFD2"
[2866] "GFUS"
[2867] "ACYP2"
[2868] "BLVRA"
[2869] "FARS2"
[2870] "SPATA6"
[2871] "AGO3"
[2872] "MIS18BP1"
[2873] "SLC25A23"
[2874] "NOC3L"
[2875] "MRPS6"
[2876] "PAK4"
[2877] "ISCA1"
[2878] "GPC4"
[2879] "PXMP2"
[2880] "WDR45B"
[2881] "COTL1"
[2882] "CERS5"
[2883] "DIDO1"
[2884] "SLC9A1"
[2885] "ALKBH5"
[2886] "LSM6"
[2887] "LRRFIP1"
[2888] "SERPINB12"
[2889] "DDX41"
[2890] "NHERF2"
[2891] "RCOR1"
[2892] "COQ10A"
[2893] "SLK"
[2894] "BLTP3A"
[2895] "HSD17B7"
[2896] "TRDN"
[2897] "ITFG1"
[2898] "NID2"
[2899] "INTS1"
[2900] "ACTR10"
[2901] "TTC19"
[2902] "SNRPG"
[2903] "PDXK"
[2904] "TUBG1"
[2905] "AP1G2"
[2906] "REEP4"
[2907] "PPCS"
[2908] "GSTM3"
[2909] "KIFBP"
[2910] "APRT"
[2911] "MCUR1"
[2912] "GSTM2"
[2913] "ERBIN"
[2914] "MRPS10"
[2915] "PGP"
[2916] "TMEM9"
[2917] "ARL3"
[2918] "SLC25A40"
[2919] "TANC1"
[2920] "RDH10"
[2921] "LGR4"
[2922] "STUB1"
[2923] "COA3"
[2924] "MRPL43"
[2925] "DHX29"
[2926] "ABCB6"
[2927] "THOC3"
[2928] "DUOX2"
[2929] "CFAP20"
[2930] "INTS13"
[2931] "SLIT3"
[2932] "RALGAPA2"
[2933] "EXOSC8"
[2934] "ATP7A"
[2935] "PES1"
[2936] "DSC2"
[2937] "INTS10"
[2938] "WDR33"
[2939] "MTUS1"
[2940] "CLCN6"
[2941] "KDM3B"
[2942] "SAE1"
[2943] "AMACR"
[2944] "CCN1"
[2945] "RBM42"
[2946] "CYP20A1"
[2947] "GOLGA4"
[2948] "SUGCT"
[2949] "CDK7"
[2950] "GTPBP4"
[2951] "TGFB2"
[2952] "KLHL31"
[2953] "EPN2"
[2954] "SCAF11"
[2955] "TCEA2"
[2956] "GALNT7"
[2957] "NRIP1"
[2958] "POLG2"
[2959] "NXT1"
[2960] "SUMO1"
[2961] "MBOAT2"
[2962] "TPBG"
[2963] "GSDME"
[2964] "LGALS8"
[2965] "LGALS3"
[2966] "COL5A1"
[2967] "EI24"
[2968] "VPS33A"
[2969] "PANK4"
[2970] "CENPJ"
[2971] "KRT23"
[2972] "CEP290"
[2973] "TBCB"
[2974] "LRCH4"
[2975] "PACSIN3"
[2976] "BNIP3"
[2977] "PPIL1"
[2978] "POLR2E"
[2979] "CSN2"
[2980] "TMEM179B"
[2981] "SLC25A35"
[2982] "NUP50"
[2983] "WWC1"
[2984] "DCBLD2"
[2985] "CRABP2"
[2986] "GOLGA6L2"
[2987] "TLR7"
[2988] "SARAF"
[2989] "PRR14L"
[2990] "PFKFB2"
[2991] "MSH6"
[2992] "MPP1"
[2993] "ANKRD17"
[2994] "SIDT2"
[2995] "SPTBN5"
[2996] "PRKCA"
[2997] "SLC52A2"
[2998] "NOTCH2"
[2999] "RPL22L1"
[3000] "CTAGE1"
[3001] "CPQ"
[3002] "ZMYM2"
[3003] "EPB41L1"
[3004] "EIF2AK2"
[3005] "SIN3A"
[3006] "GSTZ1"
[3007] "GOPC"
[3008] "COL5A3"
[3009] "PSMD5"
[3010] "PRPF38B"
[3011] "TFB2M"
[3012] "EVC"
[3013] "PDGFD"
[3014] "PCDHGB6"
[3015] "ATP8A2"
[3016] "NEK9"
[3017] "TEAD1"
[3018] "RNF121"
[3019] "TMEM41A"
[3020] "ARG1"
[3021] "MOSPD2"
[3022] "ATL3"
[3023] "CCDC13"
[3024] "DCUN1D1"
[3025] "MKI67"
[3026] "NCOA3"
[3027] "TEFM"
[3028] "RTL8C"
[3029] "RPRD2"
[3030] "CD9"
[3031] "ABCC4"
[3032] "CTCF"
[3033] "SETX"
[3034] "TNPO3"
[3035] "RFC5"
[3036] "CCDC124"
[3037] "PPP1R8"
[3038] "STX5"
[3039] "PTP4A2"
[3040] "TMBIM6"
[3041] "TMT1A"
[3042] "SLC25A51"
[3043] "TCAP"
[3044] "IAH1"
[3045] "GUF1"
[3046] "CISD3"
[3047] "ISG15"
[3048] "VPS51"
[3049] "SC5D"
[3050] "RAB3GAP2"
[3051] "GTF3C4"
[3052] "BRD4"
[3053] "FKBP5"
[3054] "DAPK3"
[3055] "LDHD"
[3056] "EXOC3L1"
[3057] "SUPT4H1"
[3058] "BRIX1"
[3059] "NFYC"
[3060] "CHDH"
[3061] "RSF1"
[3062] "CD36"
[3063] "THYN1"
[3064] "ICAM1"
[3065] "MRC2"
[3066] "METTL17"
[3067] "LIG3"
[3068] "DOCK3"
[3069] "BICD1"
[3070] "B3GLCT"
[3071] "COQ7"
[3072] "MOB1B"
[3073] "FAM20B"
[3074] "INPP4A"
[3075] "EXOSC4"
[3076] "DIP2B"
[3077] "RBM28"
[3078] "GTF2H2C; GTF2H2C_2"
[3079] "TMEM87A"
[3080] "SUCO"
[3081] "INTS5"
[3082] "MMS19"
[3083] "PCM1"
[3084] "SLCO3A1"
[3085] "LOXL2"
[3086] "MKRN2"
[3087] "ANKRD63"
[3088] "VPS39"
[3089] "EDF1"
[3090] "VPS11"
[3091] "EML3"
[3092] "PDSS2"
[3093] "DIAPH3"
[3094] "FAT1"
[3095] "RNF2"
[3096] "TMEM161A"
[3097] "SLIT1"
[3098] "NHLRC3"
[3099] "ST3GAL1"
[3100] "ZCCHC8"
[3101] "UQCRH"
[3102] "FOXK1"
[3103] "WDR20"
[3104] "C17orf80"
[3105] "TTC21B"
[3106] "ABHD12B"
[3107] "ABCC12"
[3108] "NEURL4"
[3109] "HOOK2"
[3110] "IKBKG"
[3111] "F10"
[3112] "LSM7"
[3113] "ARID2"
[3114] "CACNB1"
[3115] "NINL"
[3116] "MARCKS"
[3117] "NFXL1"
[3118] "SPEN"
[3119] "DHX16"
[3120] "POLQ"
[3121] "RFX5"
[3122] "EIF2B4"
[3123] "ASCC2"
[3124] "TOR1A"
[3125] "OXSR1"
[3126] "MRPL35"
[3127] "MAN1A2"
[3128] "SRI"
[3129] "CTBS"
[3130] "CDC42EP1"
[3131] "PSAT1"
[3132] "MRM2"
[3133] "UBE2Z"
[3134] "RHEB"
[3135] "POLR1E"
[3136] "PCDHGA3"
[3137] "OPLAH"
[3138] "TEAD3"
[3139] "TMA16"
[3140] "SACS"
[3141] "POTEA"
[3142] "SEPHS1"
[3143] "SYN1"
[3144] "KDM5B"
[3145] "MAN2C1"
[3146] "EPSTI1"
[3147] "STXBP2"
[3148] "ATRAID"
[3149] "NOL6"
[3150] "MTIF3"
[3151] "ARHGEF2"
[3152] "TMTC1"
[3153] "BRD3"
[3154] "CSTA"
[3155] "DNAH10"
[3156] "GPRC5A"
[3157] "SEC11C"
[3158] "C4orf54"
[3159] "DUSP8"
[3160] "IGDCC4"
[3161] "ZMYM1"
[3162] "FSIP2"
[3163] "DEUP1"
[3164] "LIAS"
[3165] "HECTD4"
[3166] "NMUR1"
[3167] "SLC15A4"
[3168] "GEMIN5"
[3169] "CCDC14"
[3170] "ADGRL2"
[3171] "CSNK1G3"
[3172] "VPS41"
[3173] "FAR1"
[3174] "PKHD1"
[3175] "OMA1"
[3176] "CNTLN"
[3177] "MYO3A"
[3178] "SIPA1L2"
[3179] "PERM1"
[3180] "GTF3C2"
[3181] "HOOK1"
[3182] "PPHLN1"
[3183] "HEATR1"
[3184] "NIFK"
[3185] "GTF3C3"
[3186] "RBM5"
[3187] "ALOX12B"
[3188] "SYVN1"
[3189] "SMTNL2"
[3190] "CSNK1D"
[3191] "PTPRZ1"
[3192] "CEP83"
[3193] "VMA21"
[3194] "MON1A"
[3195] "PEPD"
[3196] "GTF2H3"
[3197] "EOGT"
[3198] "TRMT61B"
[3199] "PLPP1"
[3200] "PRSS1"
[3201] "PPP4R2"
[3202] "KDSR"
[3203] "EXOC7"
[3204] "TRMT6"
[3205] "DNMT1"
[3206] "GABARAPL2"
[3207] "TENT5A"
[3208] "DOCK9"
[3209] "CMTR1"
[3210] "GSE1"
[3211] "DNAJC7"
[3212] "GFPT1"
[3213] "MPP7"
[3214] "LSM14A"
[3215] "COG1"
[3216] "BOP1"
[3217] "CACNA1F"
[3218] "DPF2"
[3219] "CCNA1"
[3220] "DPAGT1"
[3221] "UROC1"
[3222] "TASOR2"
[3223] "KAT2B"
[3224] "WHRN"
[3225] "CUX2"
[3226] "GTF3C1"
[3227] "PLCE1"
[3228] "TAOK2"
[3229] "DNAH9"
[3230] "UBR3"
[3231] "RNASEL"
[3232] "CRTAM"
[3233] "MYO16"
[3234] "CEP170B"
[3235] "DACH2"
[3236] "ZFP14"
[3237] "ZDHHC13"
[3238] "GLYAT"
[3239] "FKBP14"
[3240] "ABCB4"
[3241] "ROBO1"
[3242] "EZH1"
[3243] "KDM5C"
[3244] "DTL"
[3245] "COL6A5"
[3246] "NHSL1"
[3247] "NCOR1"
[3248] "NIPBL"
[3249] "DCDC1"
[3250] "POLR1C"
[3251] "APOB"
[3252] "CDK5RAP2"
[3253] "HEATR5B"
[3254] "MRPL51"
[3255] "PBRM1"
[3256] "VRK1"
[3257] "DIXDC1"
[3258] "FRMPD1"
[3259] "RFT1"
[3260] "CHRNB3"
[3261] "MARF1"
[3262] "DNAJC8"
[3263] "BAD"
[3264] "CEP162"
[3265] "CCDC121"
[3266] "DENND5A"
[3267] "ZFP28"
[3268] "N4BP3"
[3269] "RPUSD4"
[3270] "RCSD1"
[3271] "COLGALT2"
[3272] "TRPM3"
[3273] "WASF1"
[3274] "BAZ1A"
[3275] "ORC2"
[3276] "WDR11"
[3277] "USP34"
[3278] "CEP250"
[3279] "ADGRB1"
[3280] "TIGD1"
[3281] "FAM184A"
[3282] "JAKMIP1"
[3283] "EP400"
[3284] "CLEC16A"
[3285] "TPH2"
[3286] "NUMB"
[3287] "ABCD2"
[3288] "CFAP57"
[3289] "SRCIN1"
[3290] "PHLDB1"
[3291] "CRNKL1"
[3292] "TBCEL"
[3293] "DNAAF1"
[3294] "ITGA9"
[3295] "LCA5L"
[3296] "DNMT3A"
[3297] "KLHL14"
[3298] "SCN4A"
[3299] "CACNA1D"
[3300] "ZNF740"
[3301] "VPS13C"
[3302] "ARHGAP10"
[3303] "FEN1"
[3304] "BCAS3"
[3305] "TANC2"
[3306] "TUBGCP3"
[3307] "TRIM21"
[3308] "ZWINT"
[3309] "IVNS1ABP"
[3310] "XIRP2"
[3311] "ALPK2"
[3312] "MAP3K4"
[3313] "ZNF777"
[3314] "MEPCE"
[3315] "RCOR3"
[3316] "TDRD9"
[3317] "RELL1"
[3318] "SETD2"
[3319] "FGD6"
[3320] "MAP7D3"
[3321] "IQCA1L"
[3322] "TFCP2"
[3323] "DOCK6"
[3324] "DMXL2"
[3325] "NIM1K"
[3326] "TPRX1"
[3327] "SKIC2"
[3328] "FLRT2"
[3329] "RUFY1"
[3330] "CCDC60"
[3331] "KDR"
[3332] "ELOA"
[3333] "PWWP2A"
[3334] "MAGI2"
[3335] "NFATC4"
[3336] "MCM8"
[3337] "BTBD8"
[3338] "BPTF" Enrichment Test Wrangle qvalues
# 1. Read in the comprehensive DF that contains all sample info
Full_DF %>% head() Entrez.Gene.ID Ensembl.Gene.ID Gene.Symbol Accession
1 4625 ENSG00000092054 MYH7 P12883
2 4624 ENSG00000197616 MYH6 P13533
3 7273 ENSG00000155657 TTN Q8WZ42
4 70 ENSG00000159251 ACTC1 P68032
5 58 ENSG00000143632 ACTA1 P68133
6 60 ENSG00000075624 ACTB P60709
Abundance..F1..Sample..Dox..n.a Abundance..F3..Sample..Dox..n.a
1 5.25e+10 7.41e+10
2 1.00e+09 1.47e+09
3 1.39e+10 2.08e+10
4 3.92e+10 4.11e+10
5 1.72e+07 5.81e+07
6 4.02e+09 8.43e+08
Abundance..F5..Sample..Dox..Dox Abundance..F7..Sample..Dox..Dox
1 5.28e+10 6.82e+10
2 5.11e+09 4.25e+09
3 2.19e+10 2.49e+10
4 3.76e+10 3.54e+10
5 3.85e+07 5.07e+07
6 2.04e+09 1.62e+09
Abundance..F9..Sample..Dox..Dox Abundance..F2..Control..Veh..n.a
1 6.43e+10 4.33e+10
2 2.62e+09 1.50e+09
3 2.34e+10 1.29e+10
4 3.69e+10 3.54e+10
5 6.19e+07 1.64e+07
6 1.61e+09 4.16e+09
Abundance..F4..Control..Veh..n.a Abundance..F6..Control..Veh..Veh
1 7.41e+10 7.00e+10
2 1.17e+09 2.42e+09
3 2.25e+10 2.52e+10
4 2.96e+10 3.56e+10
5 3.44e+07 5.42e+07
6 6.45e+08 1.92e+09
Abundance..F8..Control..Veh..Veh Abundance..F10..Control..Veh..Veh
1 5.64e+10 5.26e+10
2 3.67e+09 3.27e+09
3 2.46e+10 2.21e+10
4 2.98e+10 2.91e+10
5 3.36e+07 4.05e+07
6 1.81e+09 1.56e+09# 2.
# Get set of DE proteins as per BH adjusted P-value
DE_proteins_qval <- toptable_Threshold_0.05 %>%
filter(adj_q_values < 0.05) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% DE_proteins_qval)
# Subset the data frame
subset_Full_data <- Full_DF[rows, ]
# Here are the SYMBOL IDs for the DE proteins as per BH adj P value < 0.05
DE_SYMBOL_qval <- subset_Full_data$Gene.Symbol %>% unique() %>% na.omit()
DE_SYMBOL_qval [1] "ACTC1"
[2] "EEF1A1"
[3] "TUBB"
[4] "HNRNPU"
[5] "TUBB2A"
[6] "H1-4"
[7] "TUBA1A"
[8] "TUBB3"
[9] "NPM1"
[10] "H1-5"
[11] "NCL"
[12] "H1-2"
[13] "KHSRP"
[14] "BCAM"
[15] "RPL4"
[16] "TUBB6"
[17] "DPYSL3"
[18] "KRT2"
[19] ""
[20] "PRDX1"
[21] "DDX17"
[22] "PALLD"
[23] "RACK1"
[24] "EEF1G"
[25] "RPS3"
[26] "FUBP1"
[27] "CRAT"
[28] "YBX1"
[29] "DDX5"
[30] "GTF2I"
[31] "KRT5"
[32] "UGP2"
[33] "AK2"
[34] "RPL7A"
[35] "HSPA4"
[36] "LAP3"
[37] "RPS4X"
[38] "RPS3A"
[39] "PPP1CC"
[40] "PRMT1"
[41] "RPL7"
[42] "DDX3X"
[43] "PABPC1"
[44] "RPSA"
[45] "TP53BP1"
[46] "TKT"
[47] "RPL3"
[48] "HNRNPDL"
[49] "GYS1"
[50] "RPL8"
[51] "RPS9"
[52] "RPS8"
[53] "HNRNPA0"
[54] "SRRM2"
[55] "RPL13"
[56] "RPS14"
[57] "MRPL15"
[58] "GOLGB1"
[59] "NOP58"
[60] "PSMC5"
[61] "GSN"
[62] "VAT1"
[63] "ALYREF"
[64] "NUMA1"
[65] "FXR2"
[66] "RPS18"
[67] "RPS6"
[68] "PTBP2"
[69] "ARHGAP1"
[70] "CHD4"
[71] "FSCN1"
[72] "RPS11"
[73] "PABPC4"
[74] "KHDRBS1"
[75] "RPL27"
[76] "RPS20"
[77] "VARS1"
[78] "RPL13A"
[79] "SERBP1"
[80] "SMARCC2"
[81] "RPL17"
[82] "G3BP1"
[83] "ZFR"
[84] "ACAD8"
[85] "YBX3"
[86] "LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"
[87] "MTCH1"
[88] "RPL30"
[89] "PABPN1"
[90] "RPL10A"
[91] "NDUFA8"
[92] "CD59"
[93] "HSPH1"
[94] "MLEC"
[95] "CAPRIN1"
[96] "RPS15A"
[97] "RPL9; RPL9P7; RPL9P8; RPL9P9"
[98] "HDLBP"
[99] "FLII"
[100] "RPS5"
[101] "RPL26"
[102] "PTK7"
[103] "RBM39"
[104] "DDX42"
[105] "RPS16"
[106] "USP28"
[107] "SUPT16H"
[108] "RPS12"
[109] "RPL11"
[110] "DPYSL2"
[111] "RPL15"
[112] "CAPZA1"
[113] "RPL12"
[114] "ECSIT"
[115] "ARPC1A"
[116] "RPL23A"
[117] "RPL35"
[118] "XRN2"
[119] "CORO1B"
[120] "RPS2"
[121] "NDUFB9"
[122] "ATP1B3"
[123] "MRPL4"
[124] "RPL24"
[125] "RSL1D1"
[126] "LMOD2"
[127] "H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"
[128] "MRPS23"
[129] "ANKRD1"
[130] "STYXL2"
[131] "SARNP"
[132] "DKC1"
[133] "RPL18A"
[134] "KRT77"
[135] "CDC42BPB"
[136] "SIAE"
[137] "ACLY"
[138] "RPL27A"
[139] "MYBBP1A"
[140] "DDX21"
[141] "RPL21"
[142] "FAM120A"
[143] "RPS15"
[144] "UBTF"
[145] "TRIM54"
[146] "RPL14"
[147] "PYCR2"
[148] "NDUFAF4"
[149] "FBN2"
[150] "SRP14"
[151] "H1-10"
[152] "EIF3F"
[153] "RPS17"
[154] "COL4A1"
[155] "RPL29"
[156] "CDC5L"
[157] "CKB"
[158] "GYG1"
[159] "GOLIM4"
[160] "SMU1"
[161] "RPL28"
[162] "HAGH"
[163] "RPS24"
[164] "RPL35A"
[165] "RPS19"
[166] "PLRG1"
[167] "USP10"
[168] "SYNPO"
[169] "FASTKD2"
[170] "UQCRQ"
[171] "SNRPA1"
[172] "EPHA4"
[173] "TIMMDC1"
[174] "RPL34"
[175] "STRBP"
[176] "RPS23"
[177] "ERH"
[178] "SMARCA1"
[179] "MRPS18B"
[180] "PNN"
[181] "CAPN2"
[182] "CNBP"
[183] "RBM26"
[184] "MRPS7"
[185] "GLYR1"
[186] "RNMT"
[187] "MRPL46"
[188] "DDX50"
[189] "GRN"
[190] "STOM"
[191] "THBS1"
[192] "GPS1"
[193] "PPA1"
[194] "NDUFA5"
[195] "EIF3J"
[196] "RPS25"
[197] "NUCB1"
[198] "UPF1"
[199] "RPS26"
[200] "RPLP2"
[201] "SMARCA5"
[202] "IMPA1"
[203] "ARG2"
[204] "MRPL48"
[205] "FUCA1"
[206] "TRIM63"
[207] "RPL32"
[208] "MRPL27"
[209] "SNU13"
[210] "RPL36AL"
[211] "DAAM1"
[212] "GCSH"
[213] "MAGOHB"
[214] "RPL31"
[215] "COPS4"
[216] "EPB41L5"
[217] "TIA1"
[218] "SLC30A1"
[219] "FNDC3B"
[220] "DMAC2L"
[221] "MASP1"
[222] "RPL36A"
[223] "ZNF638"
[224] "LARP7"
[225] "RPS21"
[226] "PPP4C"
[227] "POMGNT1"
[228] "SNRPD2"
[229] "RPL37A"
[230] "TBL1XR1"
[231] "ATXN2L"
[232] "CHCHD6"
[233] "IK"
[234] "GJA1"
[235] "MRPL28"
[236] "VLDLR"
[237] "SYMPK"
[238] "SORBS3"
[239] "RHOB"
[240] "PQBP1"
[241] "SNX2"
[242] "LRRN4"
[243] "NUCKS1"
[244] "LIN7C"
[245] "FADS1"
[246] "MBNL1"
[247] "TNNT1"
[248] "RPS10"
[249] "MAP1LC3B"
[250] "CHTOP"
[251] "KDM1A"
[252] "XPNPEP1"
[253] "RPL36"
[254] "ATP5ME"
[255] "MRPL17"
[256] "ADNP"
[257] "STX8"
[258] "ALPK3"
[259] "ACBD5"
[260] "POLR2B"
[261] "ATP6AP2"
[262] "NAT10"
[263] "MTREX"
[264] "NOC2L"
[265] "SLC1A4"
[266] "VTI1B"
[267] "CDIPT"
[268] "PRRC2A"
[269] "TMEM192"
[270] "RCC2"
[271] "DPP3"
[272] "RAB23"
[273] "LDLR"
[274] "CDK12"
[275] "CAND2"
[276] "RBMS1"
[277] "VCAM1"
[278] "NOL9"
[279] "SCAF4"
[280] "CUX1"
[281] "MUL1"
[282] "SLC39A14"
[283] "DDX47"
[284] "RPS29"
[285] "QKI"
[286] "RTRAF"
[287] "FADS2"
[288] "RRAD"
[289] "HMGN2"
[290] "STIM1"
[291] "MACROH2A2"
[292] "CD46"
[293] "Creb1; CREB1; LOC101356881"
[294] "RPP30"
[295] "TFB1M"
[296] "CDC73"
[297] "MRPS26"
[298] "ADSL"
[299] "DDX18"
[300] "FAM3C"
[301] "EDNRA"
[302] "RPS28"
[303] "NUCB2"
[304] "MFSD10"
[305] "GNL3"
[306] "HNRNPLL"
[307] "SPHKAP"
[308] "POLR2A"
[309] "SPTLC2"
[310] "AKAP1"
[311] "SLC1A5"
[312] "DDX27"
[313] "SERPINC1"
[314] "GFER"
[315] "BAIAP2"
[316] "S1PR1"
[317] "AHSA1"
[318] "EXOSC3"
[319] "EXOSC6"
[320] "USP11"
[321] "CWC15"
[322] "EXOSC7"
[323] "RECQL"
[324] "LARP1"
[325] "OXNAD1"
[326] "YTHDF3"
[327] "LSM2"
[328] "CACNB2"
[329] "RRP8"
[330] "VASN"
[331] "SKIC8"
[332] "LARP4"
[333] "INTS3"
[334] "EXOSC10"
[335] "SMNDC1"
[336] "SH3BP4"
[337] "PRRC2C"
[338] "SMC3"
[339] "MRPL21"
[340] "LRRC10"
[341] "GIGYF2"
[342] "EXOSC2"
[343] "DPF3"
[344] "CARD19"
[345] "SIPA1L3"
[346] "SKP1"
[347] "WDR43"
[348] "MRPS6"
[349] "PAK4"
[350] "DDX41"
[351] "NHERF2"
[352] "ITFG1"
[353] "INTS1"
[354] "REEP4"
[355] "ARL3"
[356] "LGR4"
[357] "STUB1"
[358] "INTS13"
[359] "PES1"
[360] "SAE1"
[361] "RBM42"
[362] "KLHL31"
[363] "TPBG"
[364] "COL5A1"
[365] "LRCH4"
[366] "BNIP3"
[367] "POLR2E"
[368] "MSH6"
[369] "RPL22L1"
[370] "GOPC"
[371] "RPRD2"
[372] "CTCF"
[373] "PPP1R8"
[374] "PTP4A2"
[375] "FKBP5"
[376] "SUPT4H1"
[377] "MRC2"
[378] "METTL17"
[379] "VPS39"
[380] "RNF2"
[381] "ST3GAL1"
[382] "ARID2"
[383] "NINL"
[384] "SPEN"
[385] "TOR1A"
[386] "UBE2Z"
[387] "POLR1E"
[388] "PCDHGA3"
[389] "MTIF3"
[390] "OMA1"
[391] "SIPA1L2"
[392] "GTF3C3"
[393] "VMA21"
[394] "PPP4R2"
[395] "KDSR"
[396] "GABARAPL2"
[397] "BOP1"
[398] "CCNA1"
[399] "KDM5C"
[400] "HEATR5B"
[401] "MRPL51"
[402] "RFT1"
[403] "BAD"
[404] "ORC2"
[405] "JAKMIP1"
[406] "TBCEL"
[407] "SCN4A"
[408] "CACNA1D"
[409] "TANC2"
[410] "TRIM21"
[411] "MAP7D3"
[412] "MCM8" # Get background Symbol IDs
All_proteins_tested <- toptable_Threshold_0.05 %>%
filter(adj_q_values < 1) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% All_proteins_tested)
# Subset the data frame
subset_back_data <- Full_DF[rows, ]
Background_SYMBOL <- subset_back_data$Gene.Symbol %>% unique() %>% na.omit()
Background_SYMBOL [1] "MYH7"
[2] "MYH6"
[3] "TTN"
[4] "ACTC1"
[5] "ACTA1"
[6] "ACTB"
[7] "ACTG1"
[8] "MYH1"
[9] "MYH3"
[10] "MYH2"
[11] "ATP5F1B"
[12] "ATP5F1A"
[13] "MYH8"
[14] "MYH13"
[15] "MYBPC3"
[16] "HSPD1"
[17] "FLNC"
[18] "SPTAN1"
[19] "SPTBN1"
[20] "AHNAK"
[21] "TPM1"
[22] "GAPDH"
[23] "SLC25A4"
[24] "ATP2A2"
[25] "XIRP1"
[26] "ACTN2"
[27] "ACO2"
[28] "SLC25A6"
[29] "IDH2"
[30] "TNNT2"
[31] "HSPA5"
[32] "SLC25A5"
[33] "VDAC1"
[34] "HK1"
[35] "LMNA"
[36] "MYOM1"
[37] "ACTN1"
[38] "MDH2"
[39] "SORBS2"
[40] "HADHA"
[41] "LDB3"
[42] "DMD"
[43] "OBSCN"
[44] "HSPA8"
[45] "ATP1A1"
[46] "GOT2"
[47] "HNRNPA2B1"
[48] "PLEC"
[49] "VDAC2"
[50] "SERPINH1"
[51] "OGDH"
[52] "MGST3"
[53] "HSP90B1"
[54] "TPM2"
[55] "AIFM1"
[56] ""
[57] "KRT1"
[58] "P4HB"
[59] "HSPA9"
[60] "ALDOA"
[61] "SLC25A3"
[62] "ANXA2"
[63] "VCL"
[64] "POTEKP"
[65] "SYNPO2L"
[66] "VIM"
[67] "NEBL"
[68] "CLTC"
[69] "MYL3"
[70] "PRKDC"
[71] "HADHB"
[72] "FH"
[73] "MYL2"
[74] "LRPPRC"
[75] "TPM3"
[76] "EEF1A1"
[77] "UQCRC2"
[78] "FLNA"
[79] "TUBB"
[80] "ACTN4"
[81] "CTNNA1"
[82] "CKMT2"
[83] "PDHA1"
[84] "SDHA"
[85] "IMMT"
[86] "TUBB4B"
[87] "UQCRC1"
[88] "DSP"
[89] "CANX"
[90] "SVIL"
[91] "PKM"
[92] "RTN4"
[93] "HNRNPU"
[94] "KRT18"
[95] "PDHB"
[96] "MYL4"
[97] "PDIA3"
[98] "KRT8"
[99] "PRDX3"
[100] "MYH9"
[101] "NES"
[102] "FHL2"
[103] "ATP2B4"
[104] "HNRNPL"
[105] "NDUFS1"
[106] "SPTB"
[107] "ANXA6"
[108] "ATP5F1C"
[109] "ATP1A3"
[110] "CS"
[111] "CKAP4"
[112] "NNT"
[113] "ENO1"
[114] "CALR"
[115] "TPM4"
[116] "DLD"
[117] "TLN1"
[118] "KRT9"
[119] "HNRNPK"
[120] "HNRNPA1"
[121] "GLUD1"
[122] "HSPB1"
[123] "PGK1"
[124] "TUBB2A"
[125] "JUP"
[126] "H1-4"
[127] "ANK3"
[128] "PDLIM5"
[129] "SLC8A1"
[130] "KRT10"
[131] "MYO18A"
[132] "ACAT1"
[133] "ATP1A2"
[134] "PKP2"
[135] "GANAB"
[136] "DYNC1H1"
[137] "VCP"
[138] "KTN1"
[139] "ETFA"
[140] "DECR1"
[141] "DYSF"
[142] "TUBA1A"
[143] "ACAA2"
[144] "IARS2"
[145] "MYH15"
[146] "IDH3A"
[147] "CYB5R3"
[148] "HNRNPM"
[149] "EEF1A2"
[150] "HSP90AB1"
[151] "CSRP3"
[152] "GATD3B"
[153] "PPIF"
[154] "MACF1"
[155] "HSP90AA1"
[156] "PHB2"
[157] "ALB"
[158] "OPA1"
[159] "MYH10"
[160] "VDAC3"
[161] "ILF3"
[162] "DHX9"
[163] "SLC25A12"
[164] "RPS27A"
[165] "LMO7"
[166] "PDLIM1"
[167] "TRIM28"
[168] "TUBB3"
[169] "HSD17B10"
[170] "PPIB"
[171] "EPB41L3"
[172] "ITGB1"
[173] "NPM1"
[174] "COX4I1"
[175] "TPI1"
[176] "NDUFS2"
[177] "HSPE1"
[178] "H1-5"
[179] "SYNPO2"
[180] "RPN1"
[181] "SERPINB14"
[182] "LMNB1"
[183] "NONO"
[184] "TUBA4A"
[185] "ACADVL"
[186] "MYL7"
[187] "NCL"
[188] "HK2"
[189] "HSPA1B"
[190] "ABLIM1"
[191] "H2BC5"
[192] "CDH2"
[193] "SLC25A11"
[194] "MATR3"
[195] "PDIA4"
[196] "CTNNB1"
[197] "H1-2"
[198] "GPI"
[199] "SOD2"
[200] "XRCC5"
[201] "PHB1"
[202] "ANK2"
[203] "ACADM"
[204] "MYOZ2"
[205] "NEXN"
[206] "CTSB"
[207] "ENO3"
[208] "ASAH1"
[209] "DLST"
[210] "CTNND1"
[211] "ETFB"
[212] "EPRS1"
[213] "PDIA6"
[214] "ITGAV"
[215] "TNNI1"
[216] "CTSD"
[217] "DLAT"
[218] "H2BC21"
[219] "H1-3"
[220] "MDH1"
[221] "CYB5R1"
[222] "KHSRP"
[223] "SFPQ"
[224] "TLN2"
[225] "SUCLA2"
[226] "HADH"
[227] "PFKP"
[228] "RRBP1"
[229] "HNRNPA3"
[230] "RYR2"
[231] "TOMM70"
[232] "ECH1"
[233] "BCAM"
[234] "ALDH2"
[235] "EZR"
[236] "GLS"
[237] "MTCH2"
[238] "FLNB"
[239] "AFG3L2"
[240] "HYOU1"
[241] "NDUFV1"
[242] "AKAP2"
[243] "SMYD1"
[244] "TFRC"
[245] "NCAM1"
[246] "DES"
[247] "PYGB"
[248] "RPL4"
[249] "SND1"
[250] "TUBB6"
[251] "LONP1"
[252] "DPYSL3"
[253] "XRCC6"
[254] "HSD17B4"
[255] "ALDH4A1"
[256] "EEA1"
[257] "HNRNPR"
[258] "KRT2"
[259] "UQCRFS1"
[260] "SFXN1"
[261] "PGAM1"
[262] "EEF2"
[263] "RPN2"
[264] "TRAP1"
[265] "MSN"
[266] "PRDX4"
[267] "BVES"
[268] "SF3B1"
[269] "SHMT2"
[270] "IGF2BP1"
[271] "SLC25A13"
[272] "PARP1"
[273] "PRDX1"
[274] "UNC45B"
[275] "NDUFA9"
[276] "ATP5PO"
[277] "IDH3B"
[278] "DDX17"
[279] "OXCT1"
[280] "ALDH6A1"
[281] "LAMB1"
[282] "PALLD"
[283] "CNN1"
[284] "RACK1"
[285] "HNRNPD"
[286] "CYC1"
[287] "KRT19"
[288] "NDUFA10"
[289] "AP2B1"
[290] "EEF1G"
[291] "DDX39B"
[292] "LAMC1"
[293] "ACAA1"
[294] "SOD1"
[295] "HRC"
[296] "RBMX"
[297] "KRT16"
[298] "KRT14"
[299] "MFGE8"
[300] "LDHA"
[301] "ALDH7A1"
[302] "NIPSNAP2"
[303] "PRPF19"
[304] "NDUFS3"
[305] "ATP1B1"
[306] "UGGT1"
[307] "MAP4"
[308] "HNRNPH1"
[309] "RPS3"
[310] "OBSL1"
[311] "BSG"
[312] "MYL6"
[313] "PPP1R12B"
[314] "IGF2R"
[315] "ECHS1"
[316] "FUBP1"
[317] "ATP2B1"
[318] "PPP1CB"
[319] "PITRM1"
[320] "MAVS"
[321] "CRAT"
[322] "WDR1"
[323] "LDHB"
[324] "AP2A1"
[325] "LMNB2"
[326] "HNRNPH2"
[327] "SRSF1"
[328] "SRSF3"
[329] "ATAD3A"
[330] "ADD1"
[331] "ACOT9"
[332] "CHCHD3"
[333] "PRDX5"
[334] "ILF2"
[335] "PSMD2"
[336] "SYNCRIP"
[337] "ACOT1"
[338] "GNAI2"
[339] "CRIP2"
[340] "ACOT2"
[341] "PTBP1"
[342] "RFTN1"
[343] "ALDOC"
[344] "LETM1"
[345] "ABAT"
[346] "GOT1"
[347] "SNTA1"
[348] "PPP1R12A"
[349] "PGM5"
[350] "ELAVL1"
[351] "MCCC2"
[352] "PRDX2"
[353] "ECI2"
[354] "SUCLG1"
[355] "ALDH3A2"
[356] "UBA1"
[357] "ACSF2"
[358] "CPVL"
[359] "CTNNA3"
[360] "KRT6A"
[361] "QARS1"
[362] "YBX1"
[363] "MYO1C"
[364] "TIMM44"
[365] "DDX5"
[366] "SLMAP"
[367] "PDHA2"
[368] "SLC16A1"
[369] "TJP1"
[370] "EIF3A"
[371] "RDX"
[372] "IGF2BP3"
[373] "PRKCSH"
[374] "HSPA1L"
[375] "IDH3G"
[376] "TMPO"
[377] "CCT2"
[378] "GTF2I"
[379] "CPT2"
[380] "COPA"
[381] "EMC1"
[382] "DDB1"
[383] "VAPA"
[384] "KRT5"
[385] "TOMM40"
[386] "PPP1CA"
[387] "CKM"
[388] "ME2"
[389] "PCCA"
[390] "PMPCA"
[391] "ACADSB"
[392] "CCAR2"
[393] "ECI1"
[394] "POPDC2"
[395] "ACAD9"
[396] "AK3"
[397] "RHOA"
[398] "DDX1"
[399] "SAMM50"
[400] "UGP2"
[401] "VAPB"
[402] "UTRN"
[403] "TMOD1"
[404] "FXR1"
[405] "EIF4G1"
[406] "HSDL2"
[407] "ETFDH"
[408] "AASS"
[409] "FLOT1"
[410] "AK2"
[411] "RPL7A"
[412] "ACSL1"
[413] "DGLUCY"
[414] "LMAN1"
[415] "HSPA4"
[416] "IVD"
[417] "CCT8"
[418] "FDXR"
[419] "RAB2A"
[420] "SUGP2"
[421] "NIPSNAP1"
[422] "CCT3"
[423] "GNB1"
[424] "RPL6"
[425] "LAP3"
[426] "LARS1"
[427] "KPNB1"
[428] "ITGA7"
[429] "ATAD1"
[430] "MT-CO2"
[431] "CALU"
[432] "RPS4X"
[433] "FARP1"
[434] "MYH14"
[435] "CTTN"
[436] "MCCC1"
[437] "HNRNPUL2"
[438] "MTDH"
[439] "PLEKHA7"
[440] "CALD1"
[441] "TNPO1"
[442] "RPS3A"
[443] "GSTK1"
[444] "FLOT2"
[445] "TPR"
[446] "CRYZ"
[447] "SDHB"
[448] "VWA8"
[449] "SLC3A2"
[450] "H2AC20"
[451] "TOP2B"
[452] "SF3A1"
[453] "LRPAP1"
[454] "DARS2"
[455] "MFN2"
[456] "PPP1CC"
[457] "TRIM55"
[458] "CSPG4"
[459] "DSG2"
[460] "NACA"
[461] "ASPH"
[462] "PDHX"
[463] "SF3B2"
[464] "BCAT2"
[465] "CAVIN1"
[466] "CORO6"
[467] "CRYAB"
[468] "PRMT1"
[469] "FKBP10"
[470] "RBMXL1"
[471] "SEPTIN7"
[472] "NSF"
[473] "RPL7"
[474] "PDK1"
[475] "HCFC1"
[476] "SUCLG2"
[477] "SF3B3"
[478] "ATP5PB"
[479] "GLB1"
[480] "PLXNB2"
[481] "FUS"
[482] "DDX3X"
[483] "PGM1"
[484] "LMAN2"
[485] "HIBADH"
[486] "CCDC141"
[487] "AGK"
[488] "CFL1"
[489] "CAMK2D"
[490] "CCT4"
[491] "MAP1B"
[492] "LAMB2"
[493] "TXNDC5"
[494] "RPL5"
[495] "MYO18B"
[496] "HMGB1"
[497] "PRKAR2A"
[498] "GNB2"
[499] "RAB1A"
[500] "EIF3C"
[501] "ACADS"
[502] "TMED10"
[503] "MRPS22"
[504] "YWHAE"
[505] "PABPC1"
[506] "RPSA"
[507] "MTX2"
[508] "PMPCB"
[509] "DAP3"
[510] "RHOT2"
[511] "NDUFA12"
[512] "P4HA1"
[513] "MCAM"
[514] "LSS"
[515] "TP53BP1"
[516] "GFM1"
[517] "NOMO2"
[518] "RAB11B"
[519] "KRT17"
[520] "PGRMC1"
[521] "NME2"
[522] "ARVCF"
[523] "DARS1"
[524] "PCYOX1"
[525] "PSMA1"
[526] "PTCD3"
[527] "BCKDHA"
[528] "GAA"
[529] "PYGM"
[530] "CPT1A"
[531] "RAB10"
[532] "TPP1"
[533] "TKT"
[534] "NOMO1"
[535] "ALDH9A1"
[536] "NPTN"
[537] "AP2A2"
[538] "IGF2BP2"
[539] "KRT7"
[540] "PLD3"
[541] "RPL3"
[542] "ENO2"
[543] "RTCB"
[544] "MOGS"
[545] "APMAP"
[546] "PTGES2"
[547] "JPH2"
[548] "HNRNPDL"
[549] "DBN1"
[550] "DAG1"
[551] "CORO1C"
[552] "HNRNPUL1"
[553] "GYS1"
[554] "FECH"
[555] "SEC23A"
[556] "RPL8"
[557] "HP1BP3"
[558] "NOP56"
[559] "SCCPDH"
[560] "OCIAD1"
[561] "PLN"
[562] "FBL"
[563] "LNPEP"
[564] "TAF15"
[565] "RPS9"
[566] "GPC1"
[567] "CAP2"
[568] "SNRNP200"
[569] "AGPS"
[570] "RAB14"
[571] "PPA2"
[572] "MRPL37"
[573] "SSB"
[574] "HSPG2"
[575] "IARS1"
[576] "TIMM50"
[577] "APOO"
[578] "RPS8"
[579] "AP2M1"
[580] "CCT7"
[581] "HNRNPA0"
[582] "PPP2R1A"
[583] "PNPT1"
[584] "GPD2"
[585] "U2AF2"
[586] "PBXIP1"
[587] "STOML2"
[588] "PRKAR1A"
[589] "CCT5"
[590] "SRRT"
[591] "AK4"
[592] "ERP29"
[593] "ARF3"
[594] "SRRM2"
[595] "PSMD11"
[596] "DBT"
[597] "PSMD1"
[598] "LRRC59"
[599] "ACTR3"
[600] "RAB35"
[601] "KIDINS220"
[602] "RARS1"
[603] "LASP1"
[604] "RBM14"
[605] "SPEG"
[606] "COX5A"
[607] "SNRNP70"
[608] "RPS7"
[609] "RPL13"
[610] "PEBP1"
[611] "CISD1"
[612] "CAND1"
[613] "PSMC1"
[614] "SRPRB"
[615] "SFXN3"
[616] "RAB7A"
[617] "ERP44"
[618] "EIF3L"
[619] "DNAJC11"
[620] "GBE1"
[621] "RPS14"
[622] "CLIC4"
[623] "PRPF8"
[624] "ATAD3B"
[625] "EIF4A1"
[626] "PFN1"
[627] "EIF2S3"
[628] "CAPZB"
[629] "EIF4A2"
[630] "CCT6A"
[631] "NPC2"
[632] "BCAP31"
[633] "TRMT10C"
[634] "MRPL15"
[635] "IPO5"
[636] "SARS2"
[637] "GOLGB1"
[638] "NOP58"
[639] "RAB8A"
[640] "AGL"
[641] "ARL6IP5"
[642] "SRSF6"
[643] "RAB1B"
[644] "MLYCD"
[645] "PSMC4"
[646] "RBBP7"
[647] "RAC1"
[648] "ESYT1"
[649] "PSMC5"
[650] "COQ9"
[651] "PSMD3"
[652] "LARS2"
[653] "CADM1"
[654] "CNP"
[655] "GLG1"
[656] "C1QBP"
[657] "SLC25A24"
[658] "NUP210"
[659] "ACSL3"
[660] "SLC25A20"
[661] "ERO1A"
[662] "NUDT21"
[663] "PTGFRN"
[664] "CACNA2D1"
[665] "RAB6A"
[666] "TPP2"
[667] "AQP1"
[668] "GSN"
[669] "CKMT1A; CKMT1B"
[670] "COPB2"
[671] "SSBP1"
[672] "NSDHL"
[673] "GFM2"
[674] "VAT1"
[675] "PGRMC2"
[676] "FUBP3"
[677] "USO1"
[678] "DNAJB11"
[679] "TST"
[680] "PSMA7"
[681] "PDLIM3"
[682] "GRHPR"
[683] "TCP1"
[684] "ACBD3"
[685] "NME1"
[686] "PCBP1"
[687] "MYL9"
[688] "ALYREF"
[689] "PSMD13"
[690] "DDOST"
[691] "NUMA1"
[692] "MMUT"
[693] "TNNI3"
[694] "THRAP3"
[695] "HEXB"
[696] "FXR2"
[697] "PSMD12"
[698] "MRPS9"
[699] "NIPSNAP3A"
[700] "ADD3"
[701] "BCLAF1"
[702] "RAI14"
[703] "RPS18"
[704] "RPS6"
[705] "RPLP0"
[706] "YWHAZ"
[707] "PAM"
[708] "PGAM2"
[709] "LEMD2"
[710] "HNRNPF"
[711] "ATP6V1B2"
[712] "SEPTIN2"
[713] "PLOD1"
[714] "PSMB5"
[715] "TMX2"
[716] "RAB2B"
[717] "STIP1"
[718] "CPOX"
[719] "FERMT2"
[720] "MRPL3"
[721] "ACE2"
[722] "ATP6V0A1"
[723] "COL18A1"
[724] "PTBP2"
[725] "ARHGAP1"
[726] "HSD17B12"
[727] "AFDN"
[728] "STBD1"
[729] "AIMP1"
[730] "SAFB"
[731] "P4HA2"
[732] "SLC2A1"
[733] "EIF3B"
[734] "TARS2"
[735] "RAN"
[736] "ALDH5A1"
[737] "CHD4"
[738] "CASQ2"
[739] "FSCN1"
[740] "MTHFD1L"
[741] "STING1"
[742] "ALDH18A1"
[743] "YWHAG"
[744] "GNS"
[745] "RPS11"
[746] "MRPS5"
[747] "FASN"
[748] "CFL2"
[749] "POR"
[750] "PFKM"
[751] "MANBA"
[752] "TECR"
[753] "REEP5"
[754] "SUOX"
[755] "LAMA5"
[756] "FAHD2A"
[757] "ABCD3"
[758] "TACO1"
[759] "EIF4A3"
[760] "PABPC4"
[761] "GDI2"
[762] "RANBP2"
[763] "CTSC"
[764] "SPATA20"
[765] "KHDRBS1"
[766] "PSMD6"
[767] "RPL27"
[768] "SIRPA"
[769] "RPS20"
[770] "BCS1L"
[771] "MARS1"
[772] "PRKACA"
[773] "VARS1"
[774] "ADH5"
[775] "TARDBP"
[776] "RPL13A"
[777] "HSPB7"
[778] "CLPX"
[779] "AHCY"
[780] "CPSF6"
[781] "PCCB"
[782] "PARK7"
[783] "EPHA2"
[784] "SERBP1"
[785] "AKR1B1"
[786] "HDHD5"
[787] "RUVBL2"
[788] "GCDH"
[789] "SYNJ2BP"
[790] "PSMC2"
[791] "G3BP2"
[792] "ABHD11"
[793] "HCCS"
[794] "SMARCC2"
[795] "YLPM1"
[796] "PCBP2"
[797] "TGM2"
[798] "TAGLN"
[799] "EIF5A"
[800] "MYL12B"
[801] "RRAS"
[802] "CTSA"
[803] "RHOT1"
[804] "VPS35"
[805] "PRDX6"
[806] "RPL17"
[807] "G3BP1"
[808] "BAK1"
[809] "DCTN2"
[810] "TRIOBP"
[811] "SEC24C"
[812] "ZFR"
[813] "CLPB"
[814] "SGSH"
[815] "PSMA6"
[816] "EWSR1"
[817] "HNRNPAB"
[818] "ARMCX1"
[819] "ACAD8"
[820] "LRRC47"
[821] "TCOF1"
[822] "YBX3"
[823] "ALCAM"
[824] "RCN1"
[825] "EEF1D"
[826] "PUF60"
[827] "TOP1"
[828] "TNNC1"
[829] "SRPRA"
[830] "RDH13"
[831] "HSDL1"
[832] "CAV1"
[833] "LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"
[834] "NDUFV2"
[835] "PALM2"
[836] "COPB1"
[837] "SCP2"
[838] "TMED9"
[839] "MTCH1"
[840] "RPL30"
[841] "SACM1L"
[842] "STRN"
[843] "EIF3D"
[844] "CIRBP"
[845] "GNA11"
[846] "MRPL38"
[847] "MYADM"
[848] "PABPN1"
[849] "ABHD16A"
[850] "EIF3E"
[851] "PA2G4"
[852] "RAP1A"
[853] "ATP1B4"
[854] "KIF5B"
[855] "PICALM"
[856] "LNPK"
[857] "TMEM43"
[858] "RPL10A"
[859] "ZYX"
[860] "SSRP1"
[861] "NDUFA8"
[862] "EFTUD2"
[863] "ANXA1"
[864] "ATP5MG"
[865] "NAP1L4"
[866] "LRP1"
[867] "GNAS"
[868] "PIGS"
[869] "GPX1"
[870] "ERLIN2"
[871] "SCARB2"
[872] "ERBB2"
[873] "ANP32A"
[874] "VAMP3"
[875] "H2AC25"
[876] "MIPEP"
[877] "SF3A3"
[878] "COLGALT1"
[879] "PGAM5"
[880] "DAZAP1"
[881] "NDUFA11"
[882] "CD59"
[883] "CLPTM1"
[884] "MPC2"
[885] "HSPH1"
[886] "NARS1"
[887] "WFS1"
[888] "MLEC"
[889] "DHX15"
[890] "TOR1AIP1"
[891] "SEPTIN9"
[892] "GNAI1"
[893] "RPL19"
[894] "SCAMP3"
[895] "CD81"
[896] "ARL8B"
[897] "NAP1L1"
[898] "HMOX2"
[899] "BUB3"
[900] "CAPRIN1"
[901] "RPS13"
[902] "PLEKHA5"
[903] "HACD3"
[904] "EMD"
[905] "NDUFS6"
[906] "RPS15A"
[907] "SMARCA4"
[908] "RPL9; RPL9P7; RPL9P8; RPL9P9"
[909] "STT3B"
[910] "SGPL1"
[911] "RBBP4"
[912] "HDLBP"
[913] "ANXA3"
[914] "CAP1"
[915] "ATP6V1A"
[916] "GNB4"
[917] "CLIC1"
[918] "PSMA3"
[919] "CRELD1"
[920] "FLII"
[921] "ADCY5"
[922] "LGALS3BP"
[923] "RPS5"
[924] "RPL26"
[925] "RAB6B"
[926] "PELP1"
[927] "CAPZA2"
[928] "PTK7"
[929] "RBM39"
[930] "SRSF2"
[931] "ATP5F1D"
[932] "DDX42"
[933] "PDK3"
[934] "GHITM"
[935] "RPS16"
[936] "MRPS11"
[937] "RAP1B"
[938] "PLBD2"
[939] "MRPS27"
[940] "USP28"
[941] "MGST1"
[942] "UFL1"
[943] "MRPL39"
[944] "FHL1"
[945] "SUPT16H"
[946] "APOE"
[947] "HIBCH"
[948] "ACP2"
[949] "RPS12"
[950] "SART3"
[951] "PTPN1"
[952] "CAT"
[953] "ERMP1"
[954] "ACIN1"
[955] "STX7"
[956] "TXNRD2"
[957] "SCO1"
[958] "RDH11"
[959] "UBAP2L"
[960] "POLDIP2"
[961] "RAB21"
[962] "GM2A"
[963] "PDPR"
[964] "GNAI3"
[965] "RUVBL1"
[966] "RPL11"
[967] "KARS1"
[968] "HNRNPC"
[969] "SLTM"
[970] "MRPL13"
[971] "EIF4G2"
[972] "RAB12"
[973] "HMGB2"
[974] "ENDOG"
[975] "PSMB1"
[976] "ACOX1"
[977] "CDC42"
[978] "DPYSL2"
[979] "LGALS1"
[980] "PYCR1"
[981] "SEC13"
[982] "DPP7"
[983] "EIF3I"
[984] "SF1"
[985] "RPL15"
[986] "CAPZA1"
[987] "STRAP"
[988] "ABHD12"
[989] "SRSF7"
[990] "TOP2A"
[991] "TSFM"
[992] "S100A10"
[993] "PCK2"
[994] "RPL12"
[995] "MRPS31"
[996] "HMGCL"
[997] "FKBP8"
[998] "YWHAQ"
[999] "DNAJC13"
[1000] "ITGA3"
[1001] "ARSB"
[1002] "TMX3"
[1003] "SEC61A1"
[1004] "SPCS2"
[1005] "SCAMP1"
[1006] "RPL18"
[1007] "NADK2"
[1008] "HIGD1A"
[1009] "MRPL44"
[1010] "RAD23B"
[1011] "PYGL"
[1012] "RBM4"
[1013] "NDUFS8"
[1014] "HEXA"
[1015] "RNH1"
[1016] "FAF2"
[1017] "POFUT1"
[1018] "ARF4"
[1019] "SLC2A3"
[1020] "DNAJC10"
[1021] "CSNK2A1"
[1022] "NPEPPS"
[1023] "PDP1"
[1024] "NAPA"
[1025] "APEX1"
[1026] "ACTR1A"
[1027] "NASP"
[1028] "PDLIM7"
[1029] "CASK"
[1030] "RPL22"
[1031] "ARCN1"
[1032] "CSRP2"
[1033] "APOOL"
[1034] "NCLN"
[1035] "PIGT"
[1036] "DDX23"
[1037] "FARSB"
[1038] "ECSIT"
[1039] "IBA57"
[1040] "PSMC3"
[1041] "ARPC1A"
[1042] "SLC25A1"
[1043] "ARL8A"
[1044] "ITGA5"
[1045] "CLGN"
[1046] "TBRG4"
[1047] "RBM25"
[1048] "PEX11B"
[1049] "CLIC5"
[1050] "RPL23A"
[1051] "TCERG1"
[1052] "RPL35"
[1053] "HDAC2"
[1054] "RHOG"
[1055] "ACOX3"
[1056] "NIPSNAP3B"
[1057] "ARMCX2"
[1058] "RALA"
[1059] "NDUFA13"
[1060] "HNRNPH3"
[1061] "ABCD1"
[1062] "MRPS2"
[1063] "NID1"
[1064] "NUP93"
[1065] "NFS1"
[1066] "XRN2"
[1067] "FKBP3"
[1068] "YES1"
[1069] "RTN3"
[1070] "CORO1B"
[1071] "NDUFS7"
[1072] "TMEM65"
[1073] "PLA2G15"
[1074] "PRKAR2B"
[1075] "H1-0"
[1076] "H2AZ2"
[1077] "RPS2"
[1078] "COX6B1"
[1079] "DCXR"
[1080] "PSMD4"
[1081] "NDUFB9"
[1082] "GATM"
[1083] "ACTL6A"
[1084] "SPG7"
[1085] "ATP1B3"
[1086] "PSMC6"
[1087] "HOMER1"
[1088] "FKBP9"
[1089] "ACSL4"
[1090] "DSTN"
[1091] "PSMA2"
[1092] "MRPL4"
[1093] "SLC12A4"
[1094] "SEPTIN8"
[1095] "GALNT2"
[1096] "RPL24"
[1097] "MRPL1"
[1098] "ITGB5"
[1099] "CSDE1"
[1100] "PDS5B"
[1101] "PRPF6"
[1102] "SMCHD1"
[1103] "MICOS13"
[1104] "SUPV3L1"
[1105] "HMGA2"
[1106] "ABCB7"
[1107] "ERGIC1"
[1108] "MRPL9"
[1109] "SLIRP"
[1110] "DNM2"
[1111] "CAPN1"
[1112] "RAB18"
[1113] "CYB5B"
[1114] "CCDC47"
[1115] "TM9SF4"
[1116] "TMEM126A"
[1117] "MRPL24"
[1118] "FUNDC2"
[1119] "ATP5MF"
[1120] "MRPS34"
[1121] "GGH"
[1122] "PTDSS2"
[1123] "RSL1D1"
[1124] "HUWE1"
[1125] "SLC12A7"
[1126] "U2AF1"
[1127] "DEK"
[1128] "SRSF4"
[1129] "RALY"
[1130] "DCTN1"
[1131] "XPO1"
[1132] "ATP13A1"
[1133] "DTNA"
[1134] "LMOD2"
[1135] "AARS2"
[1136] "MRPL16"
[1137] "GORASP2"
[1138] "H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"
[1139] "MYOF"
[1140] "DDX46"
[1141] "MRPL19"
[1142] "MRPS23"
[1143] "PSMA4"
[1144] "ANKRD1"
[1145] "NAXE"
[1146] "PSMD7"
[1147] "CBR4"
[1148] "SCFD1"
[1149] "SLC27A6"
[1150] "STYXL2"
[1151] "PCDH7"
[1152] "FAHD1"
[1153] "GNAQ"
[1154] "MELTF"
[1155] "CDK5RAP3"
[1156] "SARNP"
[1157] "MRPL2"
[1158] "CMAS"
[1159] "MAPRE1"
[1160] "ABCB10"
[1161] "HBA1; HBA2"
[1162] "SEPTIN11"
[1163] "LAMTOR1"
[1164] "SEC63"
[1165] "PSMB7"
[1166] "RAB4A"
[1167] "PLOD3"
[1168] "EIF4E"
[1169] "PRCP"
[1170] "USP7"
[1171] "CCAR1"
[1172] "PSPC1"
[1173] "HARS2"
[1174] "PHGDH"
[1175] "NUP155"
[1176] "HSD17B8"
[1177] "SET"
[1178] "NSFL1C"
[1179] "CSNK1A1"
[1180] "STRN3"
[1181] "QDPR"
[1182] "DYNC1LI1"
[1183] "SRC"
[1184] "RTN4IP1"
[1185] "DKC1"
[1186] "PRKACB"
[1187] "CELF2"
[1188] "RPL18A"
[1189] "LPP"
[1190] "XPR1"
[1191] "CKAP5"
[1192] "PRPF4"
[1193] "STT3A"
[1194] "KRT77"
[1195] "ACTR2"
[1196] "SMARCA2"
[1197] "DHX30"
[1198] "TM9SF2"
[1199] "TMTC3"
[1200] "SEC61A2"
[1201] "RALB"
[1202] "YWHAB"
[1203] "RDH14"
[1204] "IGFBP7"
[1205] "CDKN2AIP"
[1206] "QPRT"
[1207] "GDI1"
[1208] "SLC25A10"
[1209] "CDC42BPB"
[1210] "EHD1"
[1211] "HM13"
[1212] "MTARC2"
[1213] "IDH1"
[1214] "PSMA5"
[1215] "TMEM245"
[1216] "DNAJA1"
[1217] "TMEM165"
[1218] "HMGA1"
[1219] "NDUFS4"
[1220] "PLIN3"
[1221] "MAGED2"
[1222] "MMAB"
[1223] "SIAE"
[1224] "ACLY"
[1225] "MRPL45"
[1226] "ATP5PD"
[1227] "TP53I11"
[1228] "YWHAH"
[1229] "GSR"
[1230] "PDK2"
[1231] "NRP1"
[1232] "NUP205"
[1233] "TALDO1"
[1234] "ADPRHL1"
[1235] "NEU1"
[1236] "RPL27A"
[1237] "PDCD6IP"
[1238] "ECE1"
[1239] "MYBBP1A"
[1240] "FMR1"
[1241] "PYROXD2"
[1242] "RCC1"
[1243] "CHID1"
[1244] "HDHD3"
[1245] "PLS3"
[1246] "AGRN"
[1247] "DDX21"
[1248] "MRPL47"
[1249] "ST13"
[1250] "SAFB2"
[1251] "PAFAH1B1"
[1252] "MYDGF"
[1253] "MTIF2"
[1254] "SMARCD3"
[1255] "CSTF3"
[1256] "EIF2S1"
[1257] "CPSF7"
[1258] "TBL2"
[1259] "PSIP1"
[1260] "PREB"
[1261] "VAMP2"
[1262] "PPP2CA"
[1263] "RO60"
[1264] "ACAD10"
[1265] "CTSZ"
[1266] "SMARCC1"
[1267] "MAPK1"
[1268] "GOLGA2"
[1269] "NDUFB6"
[1270] "COPG1"
[1271] "RPL21"
[1272] "PNKD"
[1273] "FAM120A"
[1274] "CYP2J2"
[1275] "SNAP23"
[1276] "HLA-A"
[1277] "RPS15"
[1278] "MCM5"
[1279] "GARS1"
[1280] "CSTF1"
[1281] "GRSF1"
[1282] "API5"
[1283] "MT-ND5"
[1284] "CSE1L"
[1285] "NECTIN2"
[1286] "MRPS12"
[1287] "TMEM205"
[1288] "UBTF"
[1289] "NDRG2"
[1290] "AHNAK2"
[1291] "DHCR7"
[1292] "ARPC2"
[1293] "TRIM54"
[1294] "SLC7A5"
[1295] "ATP6V0D1"
[1296] "RRAS2"
[1297] "YARS1"
[1298] "VCAN"
[1299] "ANXA11"
[1300] "SLC20A2"
[1301] "FHOD3"
[1302] "RPL14"
[1303] "PFKL"
[1304] "MRPS30"
[1305] "ABCC1"
[1306] "LYN"
[1307] "MTA1"
[1308] "FARSA"
[1309] "PYCR2"
[1310] "MBOAT7"
[1311] "DDX6"
[1312] "AKR7A2"
[1313] "AUH"
[1314] "CNTNAP1"
[1315] "TMEM109"
[1316] "XPNPEP3"
[1317] "NDUFAF4"
[1318] "U2SURP"
[1319] "ARMCX3"
[1320] "NDUFA7"
[1321] "PSMD8"
[1322] "MRPL14"
[1323] "FBN2"
[1324] "ABHD10"
[1325] "H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"
[1326] "SRP14"
[1327] "H1-10"
[1328] "RAB3A"
[1329] "BCL2L13"
[1330] "MARCHF5"
[1331] "EIF3F"
[1332] "COQ5"
[1333] "PSMB6"
[1334] "STAT3"
[1335] "MSRB2"
[1336] "SLC44A2"
[1337] "EPHX1"
[1338] "PPT1"
[1339] "UCHL1"
[1340] "ACOT13"
[1341] "ADAM10"
[1342] "ILVBL"
[1343] "RER1"
[1344] "SAP18"
[1345] "LYPLAL1"
[1346] "ARHGDIA"
[1347] "TFG"
[1348] "OXA1L"
[1349] "PSMB4"
[1350] "TP53I3"
[1351] "IPO7"
[1352] "RPS17"
[1353] "ISOC2"
[1354] "SLC35E1"
[1355] "FOXRED1"
[1356] "ANKFY1"
[1357] "MRPS35"
[1358] "NBAS"
[1359] "DNAJA2"
[1360] "PSAP"
[1361] "SIRT5"
[1362] "COL4A1"
[1363] "MRPS18A"
[1364] "KPNA2"
[1365] "RPL29"
[1366] "FXYD6"
[1367] "STX12"
[1368] "MTA2"
[1369] "CAMK2A"
[1370] "SSR4"
[1371] "EIF4H"
[1372] "CDC5L"
[1373] "TIMM21"
[1374] "CADM4"
[1375] "CKB"
[1376] "MRPL58"
[1377] "NAGLU"
[1378] "TIMM17B"
[1379] "TXNL1"
[1380] "CPS1"
[1381] "MRPS25"
[1382] "CPNE3"
[1383] "GYG1"
[1384] "USP5"
[1385] "NDUFB3"
[1386] "GOLIM4"
[1387] "RAB5B"
[1388] "MTX1"
[1389] "SMU1"
[1390] "EIF3H"
[1391] "MRPL22"
[1392] "ILK"
[1393] "CISD2"
[1394] "L2HGDH"
[1395] "PAICS"
[1396] "EIF5B"
[1397] "RPL28"
[1398] "HAGH"
[1399] "HIP1"
[1400] "MPC1"
[1401] "HRNR"
[1402] "RPA1"
[1403] "RPS24"
[1404] "LAMP1"
[1405] "TMED4"
[1406] "RPS27"
[1407] "PSMB2"
[1408] "ERAP1"
[1409] "ATIC"
[1410] "GPRIN3"
[1411] "SF3A2"
[1412] "CXADR"
[1413] "RPL35A"
[1414] "RAB5C"
[1415] "F11R"
[1416] "MCM3"
[1417] "SFXN4"
[1418] "DCAKD"
[1419] "CACYBP"
[1420] "MESD"
[1421] "EPS15L1"
[1422] "NOLC1"
[1423] "RPS19"
[1424] "EMC2"
[1425] "NCSTN"
[1426] "DAD1"
[1427] "PGD"
[1428] "RPL23"
[1429] "SNRPA"
[1430] "MYEF2"
[1431] "AKR1A1"
[1432] "STRN4"
[1433] "GBA2"
[1434] "YME1L1"
[1435] "PLRG1"
[1436] "AMT"
[1437] "PVR"
[1438] "YARS2"
[1439] "SERPINB6"
[1440] "HTATSF1"
[1441] "USP10"
[1442] "NCKAP1"
[1443] "PPOX"
[1444] "WDR18"
[1445] "MAN2B1"
[1446] "MCM4"
[1447] "DNAJC3"
[1448] "PRXL2A"
[1449] "SYNPO"
[1450] "SNRPD1"
[1451] "FASTKD2"
[1452] "SEC31A"
[1453] "FITM2"
[1454] "UQCRQ"
[1455] "SNRPA1"
[1456] "AGPAT1"
[1457] "EPHA4"
[1458] "DNAJA3"
[1459] "TMED7"
[1460] "SLC16A3"
[1461] "TIMMDC1"
[1462] "PLXNA1"
[1463] "RAB33B"
[1464] "NAMPT"
[1465] "EXOG"
[1466] "MYLK3"
[1467] "DDRGK1"
[1468] "SORT1"
[1469] "COMTD1"
[1470] "TARS1"
[1471] "PHF5A"
[1472] "DHRS4"
[1473] "ZFPL1"
[1474] "TMEM11"
[1475] "SART1"
[1476] "HINT1"
[1477] "PON2"
[1478] "ADAR"
[1479] "SURF4"
[1480] "GLIPR2"
[1481] "CRTAP"
[1482] "RPL34"
[1483] "EIF3M"
[1484] "STRBP"
[1485] "KANK2"
[1486] "MYPN"
[1487] "NDUFAF1"
[1488] "DYNC1I2"
[1489] "LACTB"
[1490] "EBP"
[1491] "F5"
[1492] "RPS23"
[1493] "CSTF2"
[1494] "SMPD1"
[1495] "SLC39A7"
[1496] "COX5B"
[1497] "COPS2"
[1498] "AK1"
[1499] "UBXN4"
[1500] "ERH"
[1501] "TM9SF3"
[1502] "RAE1"
[1503] "HAX1"
[1504] "TMEM33"
[1505] "P3H1"
[1506] "NIT2"
[1507] "EFNB1"
[1508] "SMARCA1"
[1509] "MRPS18B"
[1510] "PNN"
[1511] "WARS1"
[1512] "CAPN2"
[1513] "RPS27L"
[1514] "STXBP3"
[1515] "BPHL"
[1516] "CNBP"
[1517] "UQCRB"
[1518] "PIGK"
[1519] "GSK3B"
[1520] "SPCS3"
[1521] "EHD3"
[1522] "RAB13"
[1523] "LUC7L2"
[1524] "ROR1"
[1525] "EHD4"
[1526] "LMAN2L"
[1527] "DNAJB4"
[1528] "RBM26"
[1529] "WDR5"
[1530] "MAGT1"
[1531] "NDUFA6"
[1532] "TMED1"
[1533] "DPM1"
[1534] "HDGF"
[1535] "ANP32B"
[1536] "RTN2"
[1537] "NLRX1"
[1538] "NUBPL"
[1539] "LUC7L3"
[1540] "CYFIP2"
[1541] "TIMM23"
[1542] "ADD2"
[1543] "TMEM201"
[1544] "EPHB3"
[1545] "GALC"
[1546] "NRAS"
[1547] "ARPC4"
[1548] "ACSF3"
[1549] "PTGR3"
[1550] "MRPS7"
[1551] "MAIP1"
[1552] "COX20"
[1553] "ETHE1"
[1554] "ENDOD1"
[1555] "CBX3"
[1556] "BCKDK"
[1557] "GET3"
[1558] "TIAL1"
[1559] "PC"
[1560] "EMC3"
[1561] "TMLHE"
[1562] "NT5DC2"
[1563] "ZNF326"
[1564] "ABCF1"
[1565] "GLYR1"
[1566] "METAP1"
[1567] "HDAC1"
[1568] "MCM6"
[1569] "MECP2"
[1570] "MAP4K4"
[1571] "VPS13A"
[1572] "FKBP2"
[1573] "TEX10"
[1574] "SLC25A46"
[1575] "HDGFL3"
[1576] "M6PR"
[1577] "EDC4"
[1578] "RNMT"
[1579] "CARS2"
[1580] "ADCY6"
[1581] "EIF3G"
[1582] "SYNGR2"
[1583] "ELOC"
[1584] "DLG1"
[1585] "NAV1"
[1586] "LMF2"
[1587] "NCBP1"
[1588] "ATPAF1"
[1589] "RUSF1"
[1590] "MT-CO1"
[1591] "GBA1"
[1592] "RBM15"
[1593] "MT-ATP6"
[1594] "FKBP4"
[1595] "C8orf82"
[1596] "MRPL46"
[1597] "DHTKD1"
[1598] "VPS45"
[1599] "TRA2B"
[1600] "WDR82"
[1601] "NAGA"
[1602] "RANGAP1"
[1603] "ROMO1"
[1604] "PLXNA2"
[1605] "RAB5A"
[1606] "DDX50"
[1607] "GRN"
[1608] "DUT"
[1609] "MT-ND1"
[1610] "SCAMP2"
[1611] "RBM3"
[1612] "MMP15"
[1613] "ERGIC3"
[1614] "BAX"
[1615] "LAMTOR3"
[1616] "FYN"
[1617] "MRPS17"
[1618] "FILIP1"
[1619] "SUGT1"
[1620] "SEPTIN6"
[1621] "EARS2"
[1622] "FAM98B"
[1623] "ISYNA1"
[1624] "STOM"
[1625] "LMOD1"
[1626] "HSPB8"
[1627] "SEC62"
[1628] "THBS1"
[1629] "LLGL1"
[1630] "PURB"
[1631] "NDUFB11"
[1632] "PRPF40A"
[1633] "MTFR1L"
[1634] "TMCO1"
[1635] "CHP1"
[1636] "PURA"
[1637] "GPS1"
[1638] "DDT"
[1639] "ABCB8"
[1640] "PPA1"
[1641] "PARVA"
[1642] "SPTLC1"
[1643] "PSMB3"
[1644] "ALG2"
[1645] "NDUFA5"
[1646] "ADAMTSL4"
[1647] "TIMM29"
[1648] "SEC11A"
[1649] "OXSM"
[1650] "SDR39U1"
[1651] "BDH1"
[1652] "YAP1"
[1653] "BLMH"
[1654] "CTBP1"
[1655] "AIMP2"
[1656] "ESYT2"
[1657] "EIF3J"
[1658] "PLXNA4"
[1659] "HCN4"
[1660] "SRP72"
[1661] "HDGFL2"
[1662] "SEC61B"
[1663] "NDUFB10"
[1664] "FAM210A"
[1665] "SNRPB"
[1666] "EMC7"
[1667] "COQ8A"
[1668] "HEBP1"
[1669] "HSP90AB4P"
[1670] "ISOC1"
[1671] "RPS25"
[1672] "TMEM214"
[1673] "NDUFAF7"
[1674] "MIA3"
[1675] "ENAH"
[1676] "CYRIB"
[1677] "TMEM14C"
[1678] "SLC25A22"
[1679] "PNPLA8"
[1680] "NUCB1"
[1681] "MT-ND4"
[1682] "VASP"
[1683] "ARID1A"
[1684] "PRPS1"
[1685] "PCMT1"
[1686] "SMARCE1"
[1687] "CPSF1"
[1688] "BCKDHB"
[1689] "NDUFB5"
[1690] "FBLIM1"
[1691] "GPAA1"
[1692] "SIRT3"
[1693] "COA1"
[1694] "EIF3K"
[1695] "TFAM"
[1696] "UBE4A"
[1697] "PTRH2"
[1698] "GCAT"
[1699] "CYFIP1"
[1700] "SRSF5"
[1701] "MTPAP"
[1702] "UPF1"
[1703] "SQOR"
[1704] "HRAS"
[1705] "CNPY3"
[1706] "APEH"
[1707] "RAD50"
[1708] "RPS26"
[1709] "SPCS1"
[1710] "GNPAT"
[1711] "SYPL1"
[1712] "EIF2S2"
[1713] "SRP68"
[1714] "HTRA1"
[1715] "PPM1G"
[1716] "PTTG1IP"
[1717] "CDK9"
[1718] "FAM162A"
[1719] "NDUFAF3"
[1720] "RPLP2"
[1721] "RRP12"
[1722] "SMARCA5"
[1723] "NUP35"
[1724] "ZMPSTE24"
[1725] "IMPA1"
[1726] "MANF"
[1727] "ARG2"
[1728] "TMEM41B"
[1729] "H6PD"
[1730] "TMX1"
[1731] "PTPRM"
[1732] "AHSG"
[1733] "PPP1R12C"
[1734] "MRPL48"
[1735] "INPP5A"
[1736] "SOD3"
[1737] "ZRANB2"
[1738] "FUCA1"
[1739] "OSBPL8"
[1740] "HAPLN1"
[1741] "NOP2"
[1742] "SNRPB2"
[1743] "COQ3"
[1744] "TRIM63"
[1745] "SLC27A4"
[1746] "RPL32"
[1747] "SRSF11"
[1748] "ZW10"
[1749] "GNAO1"
[1750] "SMARCB1"
[1751] "APLP2"
[1752] "ERGIC2"
[1753] "PTPRK"
[1754] "MACROD1"
[1755] "PLOD2"
[1756] "AP3M1"
[1757] "SH3GLB1"
[1758] "SLC25A21"
[1759] "SORD"
[1760] "RBM12"
[1761] "MRE11"
[1762] "GSTO1"
[1763] "TMEM70"
[1764] "UBQLN1"
[1765] "HTRA2"
[1766] "PREP"
[1767] "ACO1"
[1768] "SAR1A"
[1769] "UFSP2"
[1770] "NME3"
[1771] "SCO2"
[1772] "CDS2"
[1773] "MRPL27"
[1774] "ATP2C1"
[1775] "TMEM256"
[1776] "GNA13"
[1777] "MPST"
[1778] "DOCK7"
[1779] "DCTN4"
[1780] "HARS1"
[1781] "PROS1"
[1782] "LBR"
[1783] "SNU13"
[1784] "HGS"
[1785] "ITGA1"
[1786] "NPLOC4"
[1787] "GAPDHS"
[1788] "CD44"
[1789] "EMC8"
[1790] "ADRM1"
[1791] "CNN3"
[1792] "LCLAT1"
[1793] "ARL1"
[1794] "FASTKD1"
[1795] "LETMD1"
[1796] "CELF1"
[1797] "RPL36AL"
[1798] "PTGES3"
[1799] "POFUT2"
[1800] "DAAM1"
[1801] "LEMD3"
[1802] "CAVIN4"
[1803] "GCSH"
[1804] "DIPK2A"
[1805] "RAP2C"
[1806] "MAGOHB"
[1807] "NUP98"
[1808] "RPL31"
[1809] "COL6A1"
[1810] "NDUFB8"
[1811] "BCAP29"
[1812] "SDHC"
[1813] "PRKRA"
[1814] "TRA2A"
[1815] "CPSF2"
[1816] "COX6C"
[1817] "CES1"
[1818] "NUP133"
[1819] "CD99L2"
[1820] "NDUFA2"
[1821] "AP3B1"
[1822] "TAMM41"
[1823] "B3GAT3"
[1824] "PPIC"
[1825] "ARSA"
[1826] "MRPS15"
[1827] "ATP5IF1"
[1828] "COPS5"
[1829] "MRPL20"
[1830] "MRPS14"
[1831] "NXF1"
[1832] "COPS4"
[1833] "MICOS10"
[1834] "EPM2AIP1"
[1835] "YTHDC1"
[1836] "NIBAN1"
[1837] "EPB41L5"
[1838] "LANCL2"
[1839] "TXNRD1"
[1840] "SORBS1"
[1841] "OAT"
[1842] "TMEM38B"
[1843] "COQ6"
[1844] "BRI3BP"
[1845] "EMC4"
[1846] "DDAH2"
[1847] "WBP11"
[1848] "OVCA2"
[1849] "MRPS16"
[1850] "COL3A1"
[1851] "DNM1L"
[1852] "ECHDC1"
[1853] "GATB"
[1854] "TIA1"
[1855] "SLC30A1"
[1856] "SPNS1"
[1857] "ATP11A"
[1858] "TMEM40"
[1859] "SAR1B"
[1860] "FNDC3B"
[1861] "ACSS3"
[1862] "EPB41"
[1863] "UBQLN2"
[1864] "BTN2A1"
[1865] "SLC7A6"
[1866] "SRRM1"
[1867] "RABL3"
[1868] "EXOC4"
[1869] "COQ8B"
[1870] "PLAA"
[1871] "PACS1"
[1872] "PHPT1"
[1873] "NUP88"
[1874] "MTOR"
[1875] "DTYMK"
[1876] "EIF4B"
[1877] "RMDN1"
[1878] "DMAC2L"
[1879] "CLCN7"
[1880] "RBM10"
[1881] "MASP1"
[1882] "SNRNP40"
[1883] "SEC23IP"
[1884] "ARPC1B"
[1885] "GALNS"
[1886] "USE1"
[1887] "GPX8"
[1888] "FIP1L1"
[1889] "ITPRIP"
[1890] "SEH1L"
[1891] "H3-3A; H3-3B"
[1892] "RPL36A"
[1893] "SLC35B2"
[1894] "SLC25A15"
[1895] "PAK2"
[1896] "MRPL10"
[1897] "ZNF638"
[1898] "PSMD14"
[1899] "RANBP6"
[1900] "LARP7"
[1901] "MICAL3"
[1902] "ERLIN1"
[1903] "DGUOK"
[1904] "NUDT9"
[1905] "AP1G1"
[1906] "EFR3A"
[1907] "CD151"
[1908] "ATP6V1H"
[1909] "ZC3H14"
[1910] "FBLN1"
[1911] "COA7"
[1912] "ETF1"
[1913] "STAU1"
[1914] "KPNA6"
[1915] "ARMC1"
[1916] "NANS"
[1917] "RBPMS2"
[1918] "PALS2"
[1919] "TMEM132A"
[1920] "RPS21"
[1921] "UBE2M"
[1922] "AKAP8L"
[1923] "SEPTIN10"
[1924] "RABAC1"
[1925] "DDX24"
[1926] "STX4"
[1927] "KYAT3"
[1928] "PPP4C"
[1929] "TUSC3"
[1930] "MRPS36"
[1931] "POGLUT1"
[1932] "GPAT3"
[1933] "COPZ1"
[1934] "POMGNT1"
[1935] "ERLEC1"
[1936] "PCNA"
[1937] "HSPA13"
[1938] "MGST2"
[1939] "PPFIBP1"
[1940] "PLCD3"
[1941] "MARK2"
[1942] "DHODH"
[1943] "TPT1"
[1944] "DGAT1"
[1945] "ATPAF2"
[1946] "SUPT5H"
[1947] "MGME1"
[1948] "ATP6AP1"
[1949] "PRMT5"
[1950] "MCU"
[1951] "NARS2"
[1952] "CUL4B"
[1953] "NUP153"
[1954] "CNPY2"
[1955] "SNRPD2"
[1956] "EEF1B2"
[1957] "MTFP1"
[1958] "UQCR10"
[1959] "RPL37A"
[1960] "APOBEC2"
[1961] "WLS"
[1962] "ACAD11"
[1963] "PPTC7"
[1964] "TBL1XR1"
[1965] "NUDT19"
[1966] "CENPV"
[1967] "KIAA2013"
[1968] "MCM7"
[1969] "ATXN2L"
[1970] "EIF6"
[1971] "KPNA4"
[1972] "YIF1B"
[1973] "TEX264"
[1974] "LAMA2"
[1975] "CALM3"
[1976] "CD63"
[1977] "ITSN1"
[1978] "CUL3"
[1979] "SF3B4"
[1980] "MVP"
[1981] "UFD1"
[1982] "PAFAH1B3"
[1983] "RYR3"
[1984] "CHCHD6"
[1985] "RBM24"
[1986] "ELOVL1"
[1987] "ISCA2"
[1988] "RRAGA"
[1989] "MRPS24"
[1990] "CAPNS1"
[1991] "COPS6"
[1992] "EPPK1"
[1993] "IK"
[1994] "NCOA5"
[1995] "LIN7A"
[1996] "VKORC1L1"
[1997] "GK"
[1998] "DNAJC5"
[1999] "VPS26A"
[2000] "GJA1"
[2001] "ODR4"
[2002] "MRPL50"
[2003] "OLA1"
[2004] "UBE2V1"
[2005] "CSNK2B"
[2006] "FUCA2"
[2007] "KPNA3"
[2008] "GLRX5"
[2009] "USP39"
[2010] "NCEH1"
[2011] "CDK11B"
[2012] "PML"
[2013] "MRPL28"
[2014] "ATP13A3"
[2015] "VLDLR"
[2016] "SRPK2"
[2017] "CCDC51"
[2018] "SLC30A5"
[2019] "NUP43"
[2020] "BZW2"
[2021] "LYPLA1"
[2022] "MTX3"
[2023] "LAS1L"
[2024] "COL4A2"
[2025] "TMX4"
[2026] "ROR2"
[2027] "CUL4A"
[2028] "PIP4P2"
[2029] "EMC6"
[2030] "UBE2N"
[2031] "DMAC1"
[2032] "DCAF8"
[2033] "SYMPK"
[2034] "TRIP12"
[2035] "DST"
[2036] "COPE"
[2037] "GBF1"
[2038] "LANCL1"
[2039] "SORBS3"
[2040] "RHOB"
[2041] "ATP1B2"
[2042] "NMT1"
[2043] "OGT"
[2044] "SLC30A6"
[2045] "CLPTM1L"
[2046] "DRG1"
[2047] "CHERP"
[2048] "RANBP3"
[2049] "MRPL32"
[2050] "MYO1B"
[2051] "MT-ND2"
[2052] "DNAJB6"
[2053] "IKBIP"
[2054] "GDE1"
[2055] "PQBP1"
[2056] "ACOT11"
[2057] "PRPF3"
[2058] "TMEM106B"
[2059] "COPG2"
[2060] "TXNDC17"
[2061] "SMC1A"
[2062] "SLC29A1"
[2063] "HS2ST1"
[2064] "MRAS"
[2065] "VTN"
[2066] "IDE"
[2067] "MRPL11"
[2068] "EPDR1"
[2069] "MARS2"
[2070] "NSUN2"
[2071] "NUP160"
[2072] "HMGB3"
[2073] "MPDU1"
[2074] "NAT14"
[2075] "MMGT1"
[2076] "DBNL"
[2077] "SNX2"
[2078] "UCHL5"
[2079] "PARS2"
[2080] "POGZ"
[2081] "PRKAA1"
[2082] "DECR2"
[2083] "RBX1"
[2084] "LRRN4"
[2085] "ANTXR2"
[2086] "NUCKS1"
[2087] "CBR1"
[2088] "GART"
[2089] "ANXA7"
[2090] "ESD"
[2091] "SURF1"
[2092] "MGAT2"
[2093] "AP3D1"
[2094] "EMILIN2"
[2095] "PSME3"
[2096] "ACOT8"
[2097] "FAM136A"
[2098] "SIGMAR1"
[2099] "LIN7C"
[2100] "FADS1"
[2101] "MBNL1"
[2102] "SCN5A"
[2103] "COPS8"
[2104] "TNNT1"
[2105] "TIMM22"
[2106] "RPS10"
[2107] "MFF"
[2108] "ZNF207"
[2109] "PXN"
[2110] "PEX14"
[2111] "SNX27"
[2112] "MAP1LC3B"
[2113] "GUSB"
[2114] "TMED2"
[2115] "CHTOP"
[2116] "KDM1A"
[2117] "GSPT1"
[2118] "PARL"
[2119] "DNAJB2"
[2120] "TXNDC12"
[2121] "TOP1MT"
[2122] "XPNPEP1"
[2123] "RPL36"
[2124] "NUP214"
[2125] "FIS1"
[2126] "ATP5ME"
[2127] "GTPBP6"
[2128] "GLO1"
[2129] "PI4KA"
[2130] "MRPL17"
[2131] "DHCR24"
[2132] "NDUFA4"
[2133] "EIF5"
[2134] "TMEM30A"
[2135] "ADNP"
[2136] "TMEM115"
[2137] "MRPL12"
[2138] "STX8"
[2139] "TIMP3"
[2140] "CBX5"
[2141] "DHRS7B"
[2142] "PABPC5"
[2143] "ATG9A"
[2144] "FDFT1"
[2145] "NDUFS5"
[2146] "SLC30A9"
[2147] "ALPK3"
[2148] "FASTKD5"
[2149] "EIF2A"
[2150] "NRAP"
[2151] "SPR"
[2152] "CDH11"
[2153] "SLC35F6"
[2154] "NEK7"
[2155] "ACBD5"
[2156] "CNN2"
[2157] "PPP5C"
[2158] "MFN1"
[2159] "POLR2B"
[2160] "SELENOI"
[2161] "BPNT2"
[2162] "ALG9"
[2163] "BAG3"
[2164] "SLC2A4"
[2165] "SRSF10"
[2166] "PLS1"
[2167] "MRPL23"
[2168] "PCYOX1L"
[2169] "HINT2"
[2170] "ITGA6"
[2171] "ATP6AP2"
[2172] "BAG6"
[2173] "SYNE1"
[2174] "NAT10"
[2175] "UBA3"
[2176] "KDELR1"
[2177] "LAMP2"
[2178] "MTREX"
[2179] "CTBP2"
[2180] "GPX4"
[2181] "GOSR2"
[2182] "USP9X"
[2183] "CIAPIN1"
[2184] "VKORC1"
[2185] "NOC2L"
[2186] "TM7SF2"
[2187] "AAAS"
[2188] "TOMM20"
[2189] "ADAM9"
[2190] "CPSF3"
[2191] "RP2"
[2192] "NUDT5"
[2193] "COMT"
[2194] "TMED5"
[2195] "MRPS28"
[2196] "SDF2L1"
[2197] "MPRIP"
[2198] "SLC1A4"
[2199] "COX7A2L"
[2200] "MTHFS"
[2201] "VTI1B"
[2202] "GGCX"
[2203] "RIDA"
[2204] "COX15"
[2205] "TRMU"
[2206] "ANO6"
[2207] "CPNE5"
[2208] "CLDN6"
[2209] "TMEM259"
[2210] "NUP58"
[2211] "SMS"
[2212] "PDLIM4"
[2213] "CRELD2"
[2214] "NDUFB7"
[2215] "ELOB"
[2216] "CDIPT"
[2217] "IGF1R"
[2218] "MAP2K1"
[2219] "UBR4"
[2220] "WARS2"
[2221] "SSR3"
[2222] "PRRC2A"
[2223] "THEM6"
[2224] "PRKAA2"
[2225] "TMEM192"
[2226] "RCC2"
[2227] "NIT1"
[2228] "TES"
[2229] "NRM"
[2230] "DPP3"
[2231] "CD47"
[2232] "SRP54"
[2233] "PPP2R5A"
[2234] "AGFG1"
[2235] "LDHAL6B"
[2236] "RRAGC"
[2237] "RAB23"
[2238] "NUP54"
[2239] "ABI1"
[2240] "REXO2"
[2241] "ELMOD2"
[2242] "STRA6"
[2243] "TMEM167A"
[2244] "PHLDB2"
[2245] "SLC38A10"
[2246] "SARS1"
[2247] "GPD1L"
[2248] "SYNE2"
[2249] "MECR"
[2250] "AARS1"
[2251] "MID1"
[2252] "UBE2J1"
[2253] "CNDP2"
[2254] "TOR1AIP2"
[2255] "SLC7A1"
[2256] "PHF6"
[2257] "SELENOT"
[2258] "MSMO1"
[2259] "MCM2"
[2260] "SNRPD3"
[2261] "PIN1"
[2262] "UACA"
[2263] "LDLR"
[2264] "CDK12"
[2265] "CAND2"
[2266] "PAFAH1B2"
[2267] "SLC22A18"
[2268] "FDPS"
[2269] "CTNNBL1"
[2270] "TJP2"
[2271] "CPT1B"
[2272] "TRNT1"
[2273] "SIL1"
[2274] "KRT73"
[2275] "PLPBP"
[2276] "FSTL1"
[2277] "PRAF2"
[2278] "IDUA"
[2279] "ADHFE1"
[2280] "HLA-C"
[2281] "ATP5F1EP2"
[2282] "PALM"
[2283] "MPV17L2"
[2284] "RBMS1"
[2285] "SLC16A7"
[2286] "SON"
[2287] "SEC24B"
[2288] "TAX1BP3"
[2289] "LTA4H"
[2290] "THOC2"
[2291] "VPS29"
[2292] "PIP4K2A"
[2293] "ITGB1BP2"
[2294] "DNAJB1"
[2295] "GMPS"
[2296] "STK39"
[2297] "PFN2"
[2298] "RAB24"
[2299] "VCAM1"
[2300] "SNX9"
[2301] "CHPF"
[2302] "NFU1"
[2303] "SCYL1"
[2304] "ECPAS"
[2305] "ALG1"
[2306] "NOL9"
[2307] "EXOC8"
[2308] "TM9SF1"
[2309] "AGPAT3"
[2310] "KLHL41"
[2311] "BTF3L4"
[2312] "ICMT"
[2313] "JAM3"
[2314] "ITSN2"
[2315] "SCAF4"
[2316] "TMEM120A"
[2317] "DIABLO"
[2318] "PKN2"
[2319] "CUX1"
[2320] "PRORP"
[2321] "PI4K2A"
[2322] "IQGAP1"
[2323] "GTPBP10"
[2324] "NDUFAF5"
[2325] "IRF2BPL"
[2326] "STX18"
[2327] "CTPS2"
[2328] "XPO7"
[2329] "NMNAT1"
[2330] "PRRC1"
[2331] "STK26"
[2332] "TAPT1"
[2333] "MUL1"
[2334] "TSN"
[2335] "AKAP12"
[2336] "PPL"
[2337] "RINT1"
[2338] "GATAD2A"
[2339] "SLC39A14"
[2340] "UBE2L3"
[2341] "ITGB3"
[2342] "ERAL1"
[2343] "GLA"
[2344] "RAB34"
[2345] "DDX47"
[2346] "MCAT"
[2347] "ARL2"
[2348] "EIF1AX"
[2349] "NAE1"
[2350] "LACTB2"
[2351] "METTL15"
[2352] "SSR1"
[2353] "ATP6V1E1"
[2354] "LPCAT3"
[2355] "YIPF5"
[2356] "PPIG"
[2357] "RPS29"
[2358] "THNSL1"
[2359] "QKI"
[2360] "TAP1"
[2361] "ATL2"
[2362] "UNG"
[2363] "SGTA"
[2364] "NUDC"
[2365] "BAG2"
[2366] "MAT2A"
[2367] "GGT1"
[2368] "DYNLL1"
[2369] "TMEM126B"
[2370] "EIF2B3"
[2371] "PDXP"
[2372] "RTRAF"
[2373] "XXYLT1"
[2374] "MSRA"
[2375] "GOSR1"
[2376] "MMAA"
[2377] "CDH13"
[2378] "RETREG3"
[2379] "NLN"
[2380] "NDUFC2"
[2381] "STARD3NL"
[2382] "PPP6C"
[2383] "MAP2K2"
[2384] "PPP2R5E"
[2385] "CDC37"
[2386] "FADS2"
[2387] "UBE3A"
[2388] "GLRX3"
[2389] "RRAD"
[2390] "STRIP2"
[2391] "HINT3"
[2392] "RNPS1"
[2393] "STX16"
[2394] "MOB4"
[2395] "SHROOM2"
[2396] "RMDN3"
[2397] "TOM1L2"
[2398] "TSPAN18"
[2399] "ERG28"
[2400] "NDUFA3"
[2401] "HMGN2"
[2402] "MAN1B1"
[2403] "ANXA4"
[2404] "SLC4A1AP"
[2405] "STIM1"
[2406] "MIF"
[2407] "OCIAD2"
[2408] "MAGI1"
[2409] "TAPBP"
[2410] "DMAC2"
[2411] "QRSL1"
[2412] "USP14"
[2413] "MACROH2A2"
[2414] "FXN"
[2415] "DUSP3"
[2416] "CD46"
[2417] "Creb1; CREB1; LOC101356881"
[2418] "TLCD4"
[2419] "SUPT6H"
[2420] "PACSIN2"
[2421] "NDUFB1"
[2422] "MYO1D"
[2423] "IST1"
[2424] "YIF1A"
[2425] "RBMXL3"
[2426] "TSG101"
[2427] "LTF"
[2428] "RPP30"
[2429] "RRP9"
[2430] "TFB1M"
[2431] "ATP6V1C1"
[2432] "LGMN"
[2433] "MT-CYB"
[2434] "CUL5"
[2435] "RARS2"
[2436] "ARFGAP2"
[2437] "CLCN5"
[2438] "JAGN1"
[2439] "CDC73"
[2440] "SEPTIN5"
[2441] "EPB41L2"
[2442] "MRPS26"
[2443] "PITPNM1"
[2444] "SPARC"
[2445] "JPH1"
[2446] "PIP5K1A"
[2447] "ASCC3"
[2448] "ADSL"
[2449] "METAP2"
[2450] "NME4"
[2451] "KLC1"
[2452] "RPA2"
[2453] "RBM8A"
[2454] "NUDT6"
[2455] "KIRREL1"
[2456] "EHD2"
[2457] "CLCN3"
[2458] "NTPCR"
[2459] "DDX18"
[2460] "FAM3C"
[2461] "VPS18"
[2462] "PRPF4B"
[2463] "RMND1"
[2464] "VEZT"
[2465] "MBLAC2"
[2466] "EDNRA"
[2467] "CD55"
[2468] "RPS28"
[2469] "ZC3H18"
[2470] "PCBD1"
[2471] "ALG11"
[2472] "STMN1"
[2473] "TRAM1"
[2474] "MRPL40"
[2475] "GRB2"
[2476] "ARMC8"
[2477] "AAK1"
[2478] "SYNGR1"
[2479] "EDIL3"
[2480] "AP2S1"
[2481] "RAB9A"
[2482] "DDAH1"
[2483] "PPP2R5D"
[2484] "NUCB2"
[2485] "OSTC"
[2486] "MRPL41"
[2487] "RBFOX1"
[2488] "STK11IP"
[2489] "GOLGA7"
[2490] "SBDS"
[2491] "GLOD4"
[2492] "MFSD10"
[2493] "TMUB1"
[2494] "LPGAT1"
[2495] "GNL3"
[2496] "POGLUT3"
[2497] "GRPEL1"
[2498] "HNRNPLL"
[2499] "RCN2"
[2500] "CACHD1"
[2501] "DKK3"
[2502] "SUMF1"
[2503] "THOC6"
[2504] "STXBP1"
[2505] "UBE2D3"
[2506] "CERS2"
[2507] "ELAC2"
[2508] "TNIK"
[2509] "CAST"
[2510] "NPM3"
[2511] "TOMM22"
[2512] "BLVRB"
[2513] "NDUFB4"
[2514] "YIPF4"
[2515] "SFT2D3"
[2516] "RSU1"
[2517] "TWF2"
[2518] "SMAD2"
[2519] "EXOC1"
[2520] "ACP1"
[2521] "CUL2"
[2522] "ABCE1"
[2523] "GORASP1"
[2524] "FNDC3A"
[2525] "VAMP7"
[2526] "CCDC134"
[2527] "DDX19B"
[2528] "SPHKAP"
[2529] "YIPF3"
[2530] "POLR2A"
[2531] "PDE12"
[2532] "SUB1"
[2533] "DDX28"
[2534] "CHAMP1"
[2535] "SUMF2"
[2536] "SDF2"
[2537] "PPP4R3A"
[2538] "AKAP13"
[2539] "SCAF8"
[2540] "A2M"
[2541] "FITM1"
[2542] "NUP107"
[2543] "TAGLN2"
[2544] "PRPF31"
[2545] "FLAD1"
[2546] "DCAF7"
[2547] "SPTLC2"
[2548] "ATXN10"
[2549] "PIP4P1"
[2550] "SLC25A19"
[2551] "ITGA11"
[2552] "ITIH2"
[2553] "AP1M1"
[2554] "SLC12A2"
[2555] "NLRP13"
[2556] "FN3K"
[2557] "CASZ1"
[2558] "RAB9B"
[2559] "CUL1"
[2560] "NUDT16L1"
[2561] "GOLGA3"
[2562] "COX7A2"
[2563] "HPRT1"
[2564] "AKAP1"
[2565] "SLC1A5"
[2566] "LIPT2"
[2567] "GIT2"
[2568] "APP"
[2569] "CMPK1"
[2570] "COX11"
[2571] "TMEM143"
[2572] "UBA2"
[2573] "CLCC1"
[2574] "GPAT4"
[2575] "PCID2"
[2576] "DDX27"
[2577] "PDCD6"
[2578] "ATP6V1D"
[2579] "NSUN4"
[2580] "OPA3"
[2581] "SERPINC1"
[2582] "EEF1E1"
[2583] "DLG3"
[2584] "PCYT1A"
[2585] "CTSL"
[2586] "GFER"
[2587] "ALG6"
[2588] "BAIAP2"
[2589] "CSNK2A2"
[2590] "PIEZO1"
[2591] "MCEE"
[2592] "TRIM24"
[2593] "DLG2"
[2594] "CPNE1"
[2595] "HACD2"
[2596] "PRPSAP2"
[2597] "FZD2"
[2598] "LTBP1"
[2599] "NUTF2"
[2600] "RAB31"
[2601] "NAXD"
[2602] "NDUFAF2"
[2603] "GIT1"
[2604] "WWC3"
[2605] "OGFOD3"
[2606] "HHATL"
[2607] "S1PR1"
[2608] "DSC1"
[2609] "OTUB1"
[2610] "CERS6"
[2611] "FABP5"
[2612] "HOMER3"
[2613] "SELENOH"
[2614] "AHSA1"
[2615] "USP15"
[2616] "VMP1"
[2617] "BZW1"
[2618] "RBM12B"
[2619] "EXOSC3"
[2620] "PEX3"
[2621] "ANTXR1"
[2622] "EXOSC6"
[2623] "USP11"
[2624] "SLC25A14"
[2625] "ZC3H4"
[2626] "CWC15"
[2627] "DPY19L1"
[2628] "PRKAG2"
[2629] "SLC35A4"
[2630] "MAP1A"
[2631] "MRM1"
[2632] "IMPDH2"
[2633] "THOC1"
[2634] "BPNT1"
[2635] "PNPLA6"
[2636] "COPS3"
[2637] "CD99"
[2638] "YY1"
[2639] "CTNND2"
[2640] "SLC38A7"
[2641] "GPX7"
[2642] "ARMC10"
[2643] "NAPG"
[2644] "EXOC2"
[2645] "SDHD"
[2646] "CTR9"
[2647] "SNX6"
[2648] "DPF1"
[2649] "SNX18"
[2650] "REPS1"
[2651] "DERL1"
[2652] "CASP3"
[2653] "EXOSC7"
[2654] "MRPL30"
[2655] "D2HGDH"
[2656] "GALNT1"
[2657] "RBM17"
[2658] "RECQL"
[2659] "NUDT8"
[2660] "EMC10"
[2661] "POMK"
[2662] "LARP1"
[2663] "PEX16"
[2664] "CPNE4"
[2665] "LSM8"
[2666] "OXNAD1"
[2667] "YTHDF3"
[2668] "ARSD"
[2669] "PIGU"
[2670] "LSM2"
[2671] "CACNB2"
[2672] "PEX13"
[2673] "MTG1"
[2674] "SNTB2"
[2675] "SLC5A6"
[2676] "LAMTOR4"
[2677] "SCPEP1"
[2678] "DNAJC16"
[2679] "NPC1"
[2680] "SDK2"
[2681] "VPS16"
[2682] "MRRF"
[2683] "RRP8"
[2684] "DEGS1"
[2685] "SNX3"
[2686] "PTPMT1"
[2687] "STAU2"
[2688] "PIP5K1C"
[2689] "CD276"
[2690] "AGO2"
[2691] "VASN"
[2692] "SRP9"
[2693] "FHL3"
[2694] "NDRG3"
[2695] "TMEM160"
[2696] "RAB27A"
[2697] "MLST8"
[2698] "TTC7B"
[2699] "PDIA5"
[2700] "TEX2"
[2701] "ORMDL3"
[2702] "MAOB"
[2703] "WBP2"
[2704] "NDUFAF6"
[2705] "SKIC8"
[2706] "ACP6"
[2707] "SPRYD7"
[2708] "WASF2"
[2709] "BCL2L1"
[2710] "LARP4"
[2711] "F2"
[2712] "MRPL18"
[2713] "ARFGAP1"
[2714] "STARD7"
[2715] "GDPD1"
[2716] "NUP85"
[2717] "ZC3H11A"
[2718] "INTS3"
[2719] "EXOSC10"
[2720] "PSME1"
[2721] "POLG"
[2722] "VAC14"
[2723] "WDFY1"
[2724] "SMNDC1"
[2725] "TMEM177"
[2726] "GIPC1"
[2727] "MBTPS2"
[2728] "ROCK2"
[2729] "CTPS1"
[2730] "SEL1L"
[2731] "NUP37"
[2732] "PNKP"
[2733] "ABCF2"
[2734] "AGPAT4"
[2735] "RTCA"
[2736] "MTUS2"
[2737] "LLGL2"
[2738] "SH3BP4"
[2739] "POGLUT2"
[2740] "CPD"
[2741] "MAP1S"
[2742] "PRRC2C"
[2743] "WDR77"
[2744] "YIPF6"
[2745] "SLC26A2"
[2746] "ACSS2"
[2747] "FAM177A1"
[2748] "SMC3"
[2749] "TPRG1L"
[2750] "ALG12"
[2751] "MRS2"
[2752] "CLASP1"
[2753] "SMPD4"
[2754] "AUP1"
[2755] "TMEM50A"
[2756] "UQCC1"
[2757] "CLYBL"
[2758] "AHCYL2"
[2759] "DHRS7"
[2760] "CLINT1"
[2761] "MAP3K20"
[2762] "ATP8B3"
[2763] "ATP11B"
[2764] "ARHGEF7"
[2765] "AQR"
[2766] "GADD45GIP1"
[2767] "PDS5A"
[2768] "TOMM40L"
[2769] "ZNF512B"
[2770] "OSBP"
[2771] "TWF1"
[2772] "PPIH"
[2773] "MDK"
[2774] "PTPRD"
[2775] "MRPL21"
[2776] "SLC39A6"
[2777] "ARGLU1"
[2778] "EXTL3"
[2779] "RIOX1"
[2780] "TMEM97"
[2781] "GSS"
[2782] "C1orf198"
[2783] "EIF2B1"
[2784] "LRRC10"
[2785] "TSPO"
[2786] "SCRN1"
[2787] "MYO7B"
[2788] "AIDA"
[2789] "GIGYF2"
[2790] "PNPLA4"
[2791] "CCN2"
[2792] "NFIC"
[2793] "SLC38A1"
[2794] "CEPT1"
[2795] "MYO5C"
[2796] "MAN1C1"
[2797] "COQ10B"
[2798] "PRNP"
[2799] "BORCS6"
[2800] "EXD2"
[2801] "POP1"
[2802] "HAT1"
[2803] "EXOSC2"
[2804] "PLD1"
[2805] "GPC6"
[2806] "SPAG9"
[2807] "YKT6"
[2808] "SDC4"
[2809] "ROCK1"
[2810] "PUDP"
[2811] "EIF2B5"
[2812] "COASY"
[2813] "HEPH"
[2814] "DPF3"
[2815] "LRATD2"
[2816] "DYNC1LI2"
[2817] "NAA15"
[2818] "KPRP"
[2819] "LIMS1"
[2820] "TCHH"
[2821] "RAD23A"
[2822] "CLPP"
[2823] "MRM3"
[2824] "WDR44"
[2825] "CARD19"
[2826] "MSRB3"
[2827] "STAT1"
[2828] "TOLLIP"
[2829] "DHRS13"
[2830] "PTPRS"
[2831] "TECRL"
[2832] "PAIP1"
[2833] "MOXD1"
[2834] "PPAN"
[2835] "EXOC6B"
[2836] "RPS6KA3"
[2837] "SIPA1L3"
[2838] "MAT2B"
[2839] "PDCD10"
[2840] "PITPNB"
[2841] "TMEM38A"
[2842] "AURKAIP1"
[2843] "TMEM63B"
[2844] "SKP1"
[2845] "CYSTM1"
[2846] "HACD1"
[2847] "ADPGK"
[2848] "SLC31A1"
[2849] "GGT7"
[2850] "CSNK1E"
[2851] "ATXN2"
[2852] "IL1RAP"
[2853] "PDF"
[2854] "CYBC1"
[2855] "FUNDC1"
[2856] "ANKLE2"
[2857] "AKAP9"
[2858] "FAM169A"
[2859] "COX18"
[2860] "AMPD2"
[2861] "WDR43"
[2862] "NUP188"
[2863] "KIF2A"
[2864] "BDH2"
[2865] "SCFD2"
[2866] "GFUS"
[2867] "ACYP2"
[2868] "BLVRA"
[2869] "FARS2"
[2870] "SPATA6"
[2871] "AGO3"
[2872] "MIS18BP1"
[2873] "SLC25A23"
[2874] "NOC3L"
[2875] "MRPS6"
[2876] "PAK4"
[2877] "ISCA1"
[2878] "GPC4"
[2879] "PXMP2"
[2880] "WDR45B"
[2881] "COTL1"
[2882] "CERS5"
[2883] "DIDO1"
[2884] "SLC9A1"
[2885] "ALKBH5"
[2886] "LSM6"
[2887] "LRRFIP1"
[2888] "SERPINB12"
[2889] "DDX41"
[2890] "NHERF2"
[2891] "RCOR1"
[2892] "COQ10A"
[2893] "SLK"
[2894] "BLTP3A"
[2895] "HSD17B7"
[2896] "TRDN"
[2897] "ITFG1"
[2898] "NID2"
[2899] "INTS1"
[2900] "ACTR10"
[2901] "TTC19"
[2902] "SNRPG"
[2903] "PDXK"
[2904] "TUBG1"
[2905] "AP1G2"
[2906] "REEP4"
[2907] "PPCS"
[2908] "GSTM3"
[2909] "KIFBP"
[2910] "APRT"
[2911] "MCUR1"
[2912] "GSTM2"
[2913] "ERBIN"
[2914] "MRPS10"
[2915] "PGP"
[2916] "TMEM9"
[2917] "ARL3"
[2918] "SLC25A40"
[2919] "TANC1"
[2920] "RDH10"
[2921] "LGR4"
[2922] "STUB1"
[2923] "COA3"
[2924] "MRPL43"
[2925] "DHX29"
[2926] "ABCB6"
[2927] "THOC3"
[2928] "DUOX2"
[2929] "CFAP20"
[2930] "INTS13"
[2931] "SLIT3"
[2932] "RALGAPA2"
[2933] "EXOSC8"
[2934] "ATP7A"
[2935] "PES1"
[2936] "DSC2"
[2937] "INTS10"
[2938] "WDR33"
[2939] "MTUS1"
[2940] "CLCN6"
[2941] "KDM3B"
[2942] "SAE1"
[2943] "AMACR"
[2944] "CCN1"
[2945] "RBM42"
[2946] "CYP20A1"
[2947] "GOLGA4"
[2948] "SUGCT"
[2949] "CDK7"
[2950] "GTPBP4"
[2951] "TGFB2"
[2952] "KLHL31"
[2953] "EPN2"
[2954] "SCAF11"
[2955] "TCEA2"
[2956] "GALNT7"
[2957] "NRIP1"
[2958] "POLG2"
[2959] "NXT1"
[2960] "SUMO1"
[2961] "MBOAT2"
[2962] "TPBG"
[2963] "GSDME"
[2964] "LGALS8"
[2965] "LGALS3"
[2966] "COL5A1"
[2967] "EI24"
[2968] "VPS33A"
[2969] "PANK4"
[2970] "CENPJ"
[2971] "KRT23"
[2972] "CEP290"
[2973] "TBCB"
[2974] "LRCH4"
[2975] "PACSIN3"
[2976] "BNIP3"
[2977] "PPIL1"
[2978] "POLR2E"
[2979] "CSN2"
[2980] "TMEM179B"
[2981] "SLC25A35"
[2982] "NUP50"
[2983] "WWC1"
[2984] "DCBLD2"
[2985] "CRABP2"
[2986] "GOLGA6L2"
[2987] "TLR7"
[2988] "SARAF"
[2989] "PRR14L"
[2990] "PFKFB2"
[2991] "MSH6"
[2992] "MPP1"
[2993] "ANKRD17"
[2994] "SIDT2"
[2995] "SPTBN5"
[2996] "PRKCA"
[2997] "SLC52A2"
[2998] "NOTCH2"
[2999] "RPL22L1"
[3000] "CTAGE1"
[3001] "CPQ"
[3002] "ZMYM2"
[3003] "EPB41L1"
[3004] "EIF2AK2"
[3005] "SIN3A"
[3006] "GSTZ1"
[3007] "GOPC"
[3008] "COL5A3"
[3009] "PSMD5"
[3010] "PRPF38B"
[3011] "TFB2M"
[3012] "EVC"
[3013] "PDGFD"
[3014] "PCDHGB6"
[3015] "ATP8A2"
[3016] "NEK9"
[3017] "TEAD1"
[3018] "RNF121"
[3019] "TMEM41A"
[3020] "ARG1"
[3021] "MOSPD2"
[3022] "ATL3"
[3023] "CCDC13"
[3024] "DCUN1D1"
[3025] "MKI67"
[3026] "NCOA3"
[3027] "TEFM"
[3028] "RTL8C"
[3029] "RPRD2"
[3030] "CD9"
[3031] "ABCC4"
[3032] "CTCF"
[3033] "SETX"
[3034] "TNPO3"
[3035] "RFC5"
[3036] "CCDC124"
[3037] "PPP1R8"
[3038] "STX5"
[3039] "PTP4A2"
[3040] "TMBIM6"
[3041] "TMT1A"
[3042] "SLC25A51"
[3043] "TCAP"
[3044] "IAH1"
[3045] "GUF1"
[3046] "CISD3"
[3047] "ISG15"
[3048] "VPS51"
[3049] "SC5D"
[3050] "RAB3GAP2"
[3051] "GTF3C4"
[3052] "BRD4"
[3053] "FKBP5"
[3054] "DAPK3"
[3055] "LDHD"
[3056] "EXOC3L1"
[3057] "SUPT4H1"
[3058] "BRIX1"
[3059] "NFYC"
[3060] "CHDH"
[3061] "RSF1"
[3062] "CD36"
[3063] "THYN1"
[3064] "ICAM1"
[3065] "MRC2"
[3066] "METTL17"
[3067] "LIG3"
[3068] "DOCK3"
[3069] "BICD1"
[3070] "B3GLCT"
[3071] "COQ7"
[3072] "MOB1B"
[3073] "FAM20B"
[3074] "INPP4A"
[3075] "EXOSC4"
[3076] "DIP2B"
[3077] "RBM28"
[3078] "GTF2H2C; GTF2H2C_2"
[3079] "TMEM87A"
[3080] "SUCO"
[3081] "INTS5"
[3082] "MMS19"
[3083] "PCM1"
[3084] "SLCO3A1"
[3085] "LOXL2"
[3086] "MKRN2"
[3087] "ANKRD63"
[3088] "VPS39"
[3089] "EDF1"
[3090] "VPS11"
[3091] "EML3"
[3092] "PDSS2"
[3093] "DIAPH3"
[3094] "FAT1"
[3095] "RNF2"
[3096] "TMEM161A"
[3097] "SLIT1"
[3098] "NHLRC3"
[3099] "ST3GAL1"
[3100] "ZCCHC8"
[3101] "UQCRH"
[3102] "FOXK1"
[3103] "WDR20"
[3104] "C17orf80"
[3105] "TTC21B"
[3106] "ABHD12B"
[3107] "ABCC12"
[3108] "NEURL4"
[3109] "HOOK2"
[3110] "IKBKG"
[3111] "F10"
[3112] "LSM7"
[3113] "ARID2"
[3114] "CACNB1"
[3115] "NINL"
[3116] "MARCKS"
[3117] "NFXL1"
[3118] "SPEN"
[3119] "DHX16"
[3120] "POLQ"
[3121] "RFX5"
[3122] "EIF2B4"
[3123] "ASCC2"
[3124] "TOR1A"
[3125] "OXSR1"
[3126] "MRPL35"
[3127] "MAN1A2"
[3128] "SRI"
[3129] "CTBS"
[3130] "CDC42EP1"
[3131] "PSAT1"
[3132] "MRM2"
[3133] "UBE2Z"
[3134] "RHEB"
[3135] "POLR1E"
[3136] "PCDHGA3"
[3137] "OPLAH"
[3138] "TEAD3"
[3139] "TMA16"
[3140] "SACS"
[3141] "POTEA"
[3142] "SEPHS1"
[3143] "SYN1"
[3144] "KDM5B"
[3145] "MAN2C1"
[3146] "EPSTI1"
[3147] "STXBP2"
[3148] "ATRAID"
[3149] "NOL6"
[3150] "MTIF3"
[3151] "ARHGEF2"
[3152] "TMTC1"
[3153] "BRD3"
[3154] "CSTA"
[3155] "DNAH10"
[3156] "GPRC5A"
[3157] "SEC11C"
[3158] "C4orf54"
[3159] "DUSP8"
[3160] "IGDCC4"
[3161] "ZMYM1"
[3162] "FSIP2"
[3163] "DEUP1"
[3164] "LIAS"
[3165] "HECTD4"
[3166] "NMUR1"
[3167] "SLC15A4"
[3168] "GEMIN5"
[3169] "CCDC14"
[3170] "ADGRL2"
[3171] "CSNK1G3"
[3172] "VPS41"
[3173] "FAR1"
[3174] "PKHD1"
[3175] "OMA1"
[3176] "CNTLN"
[3177] "MYO3A"
[3178] "SIPA1L2"
[3179] "PERM1"
[3180] "GTF3C2"
[3181] "HOOK1"
[3182] "PPHLN1"
[3183] "HEATR1"
[3184] "NIFK"
[3185] "GTF3C3"
[3186] "RBM5"
[3187] "ALOX12B"
[3188] "SYVN1"
[3189] "SMTNL2"
[3190] "CSNK1D"
[3191] "PTPRZ1"
[3192] "CEP83"
[3193] "VMA21"
[3194] "MON1A"
[3195] "PEPD"
[3196] "GTF2H3"
[3197] "EOGT"
[3198] "TRMT61B"
[3199] "PLPP1"
[3200] "PRSS1"
[3201] "PPP4R2"
[3202] "KDSR"
[3203] "EXOC7"
[3204] "TRMT6"
[3205] "DNMT1"
[3206] "GABARAPL2"
[3207] "TENT5A"
[3208] "DOCK9"
[3209] "CMTR1"
[3210] "GSE1"
[3211] "DNAJC7"
[3212] "GFPT1"
[3213] "MPP7"
[3214] "LSM14A"
[3215] "COG1"
[3216] "BOP1"
[3217] "CACNA1F"
[3218] "DPF2"
[3219] "CCNA1"
[3220] "DPAGT1"
[3221] "UROC1"
[3222] "TASOR2"
[3223] "KAT2B"
[3224] "WHRN"
[3225] "CUX2"
[3226] "GTF3C1"
[3227] "PLCE1"
[3228] "TAOK2"
[3229] "DNAH9"
[3230] "UBR3"
[3231] "RNASEL"
[3232] "CRTAM"
[3233] "MYO16"
[3234] "CEP170B"
[3235] "DACH2"
[3236] "ZFP14"
[3237] "ZDHHC13"
[3238] "GLYAT"
[3239] "FKBP14"
[3240] "ABCB4"
[3241] "ROBO1"
[3242] "EZH1"
[3243] "KDM5C"
[3244] "DTL"
[3245] "COL6A5"
[3246] "NHSL1"
[3247] "NCOR1"
[3248] "NIPBL"
[3249] "DCDC1"
[3250] "POLR1C"
[3251] "APOB"
[3252] "CDK5RAP2"
[3253] "HEATR5B"
[3254] "MRPL51"
[3255] "PBRM1"
[3256] "VRK1"
[3257] "DIXDC1"
[3258] "FRMPD1"
[3259] "RFT1"
[3260] "CHRNB3"
[3261] "MARF1"
[3262] "DNAJC8"
[3263] "BAD"
[3264] "CEP162"
[3265] "CCDC121"
[3266] "DENND5A"
[3267] "ZFP28"
[3268] "N4BP3"
[3269] "RPUSD4"
[3270] "RCSD1"
[3271] "COLGALT2"
[3272] "TRPM3"
[3273] "WASF1"
[3274] "BAZ1A"
[3275] "ORC2"
[3276] "WDR11"
[3277] "USP34"
[3278] "CEP250"
[3279] "ADGRB1"
[3280] "TIGD1"
[3281] "FAM184A"
[3282] "JAKMIP1"
[3283] "EP400"
[3284] "CLEC16A"
[3285] "TPH2"
[3286] "NUMB"
[3287] "ABCD2"
[3288] "CFAP57"
[3289] "SRCIN1"
[3290] "PHLDB1"
[3291] "CRNKL1"
[3292] "TBCEL"
[3293] "DNAAF1"
[3294] "ITGA9"
[3295] "LCA5L"
[3296] "DNMT3A"
[3297] "KLHL14"
[3298] "SCN4A"
[3299] "CACNA1D"
[3300] "ZNF740"
[3301] "VPS13C"
[3302] "ARHGAP10"
[3303] "FEN1"
[3304] "BCAS3"
[3305] "TANC2"
[3306] "TUBGCP3"
[3307] "TRIM21"
[3308] "ZWINT"
[3309] "IVNS1ABP"
[3310] "XIRP2"
[3311] "ALPK2"
[3312] "MAP3K4"
[3313] "ZNF777"
[3314] "MEPCE"
[3315] "RCOR3"
[3316] "TDRD9"
[3317] "RELL1"
[3318] "SETD2"
[3319] "FGD6"
[3320] "MAP7D3"
[3321] "IQCA1L"
[3322] "TFCP2"
[3323] "DOCK6"
[3324] "DMXL2"
[3325] "NIM1K"
[3326] "TPRX1"
[3327] "SKIC2"
[3328] "FLRT2"
[3329] "RUFY1"
[3330] "CCDC60"
[3331] "KDR"
[3332] "ELOA"
[3333] "PWWP2A"
[3334] "MAGI2"
[3335] "NFATC4"
[3336] "MCM8"
[3337] "BTBD8"
[3338] "BPTF" GO Enrichment BP - DE_Pval
# 1.
# Do enrichment analysis of ENTREZ IDs from Padjusted value
# Perform GO enrichment analysis using the enrichGO function. We are using stringent cutoffs for Pvalue and q value in the testing! (this is good)
go_enrichment <- enrichGO(gene = DE_SYMBOL_Padj,
OrgDb = org.Hs.eg.db,
keyType = "SYMBOL",
universe = Background_SYMBOL,
ont = "BP",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05)
go_enrichment#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology BP
#...@keytype SYMBOL
#...@gene chr [1:224] "H1-4" "TUBB3" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "PRDX1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...48 enriched terms found
'data.frame': 48 obs. of 9 variables:
$ ID : chr "GO:0002181" "GO:0006412" "GO:0043043" "GO:0043604" ...
$ Description: chr "cytoplasmic translation" "translation" "peptide biosynthetic process" "amide biosynthetic process" ...
$ GeneRatio : chr "51/213" "71/213" "71/213" "73/213" ...
$ BgRatio : chr "104/3193" "317/3193" "324/3193" "374/3193" ...
$ pvalue : num 2.30e-34 9.36e-23 3.80e-22 1.29e-19 1.57e-19 ...
$ p.adjust : num 5.04e-31 1.03e-19 2.78e-19 6.88e-17 6.88e-17 ...
$ qvalue : num 4.83e-31 9.85e-20 2.67e-19 6.60e-17 6.60e-17 ...
$ geneID : chr "RPL4/RPS3/YBX1/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/YBX3/RPL30"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ ...
$ Count : int 51 71 71 73 40 73 73 34 31 64 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 # Go plot
goplot(x = go_enrichment, showCategory = 30)Warning: ggrepel: 72 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# summary of the result that most people use
plot(barplot(go_enrichment, showCategory = 20))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- go_enrichment %>% as_tibble()
GO_Tibble# A tibble: 48 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:000… cytoplasmi… 51/213 104/31… 2.30e-34 5.04e-31 4.83e-31 RPL4/… 51
2 GO:000… translation 71/213 317/31… 9.36e-23 1.03e-19 9.85e-20 NPM1/… 71
3 GO:004… peptide bi… 71/213 324/31… 3.80e-22 2.78e-19 2.67e-19 NPM1/… 71
4 GO:004… amide bios… 73/213 374/31… 1.29e-19 6.88e-17 6.60e-17 NPM1/… 73
5 GO:004… ribosome b… 40/213 118/31… 1.57e-19 6.88e-17 6.60e-17 NPM1/… 40
6 GO:000… peptide me… 73/213 383/31… 5.66e-19 2.07e-16 1.98e-16 NPM1/… 73
7 GO:003… cellular m… 73/213 407/31… 2.27e-17 7.11e-15 6.82e-15 NPM1/… 73
8 GO:001… rRNA metab… 34/213 99/3193 7.27e-17 1.99e-14 1.91e-14 NCL/D… 34
9 GO:000… rRNA proce… 31/213 85/3193 2.71e-16 6.60e-14 6.33e-14 DDX17… 31
10 GO:000… RNA proces… 64/213 356/31… 4.17e-15 9.13e-13 8.77e-13 NCL/D… 64
# ℹ 38 more rows# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biologcal Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,75))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO_Tibble$negplog <- -log(GO_Tibble$p.adjust)
# Break up into high, medium and low siignfigance groups
# 1. High
# Create a sample data frame
GO_Tibble_Upper <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 67
upper_percentile <- 100
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Upper <- GO_Tibble_Upper[GO_Tibble_Upper$negplog >= lower_value & GO_Tibble_Upper$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Upper, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0, 70))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
2. Med
# Create a sample data frame
GO_Tibble_Mid <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 33
upper_percentile <- 67
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Mid <- GO_Tibble_Mid[GO_Tibble_Mid$negplog >= lower_value & GO_Tibble_Mid$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Mid, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,10))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
3. Low
# Create a sample data frame
GO_Tibble_low <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 1
upper_percentile <- 33
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_low <- GO_Tibble_low[GO_Tibble_low$negplog >= lower_value & GO_Tibble_low$negplog <= upper_value, ]
GO_Tibble_low# A tibble: 15 × 10
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <fct> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:0042770 signal tra… 8/213 32/3193 8.94e-4 0.0417 0.0400 DDX5/… 8
2 GO:0006402 mRNA catab… 14/213 82/3193 8.47e-4 0.0404 0.0387 NPM1/… 14
3 GO:0045934 negative r… 29/213 238/31… 8.28e-4 0.0403 0.0387 H1-4/… 29
4 GO:0051053 negative r… 8/213 31/3193 7.11e-4 0.0366 0.0352 H1-4/… 8
5 GO:0045727 positive r… 12/213 63/3193 7.28e-4 0.0366 0.0352 NPM1/… 12
6 GO:0010557 positive r… 36/213 317/31… 7.36e-4 0.0366 0.0352 NPM1/… 36
7 GO:0072331 signal tra… 9/213 38/3193 6.56e-4 0.0350 0.0336 DDX5/… 9
8 GO:0000375 RNA splici… 21/213 148/31… 6.35e-4 0.0348 0.0334 NCL/D… 21
9 GO:0031324 negative r… 49/213 469/31… 5.36e-4 0.0301 0.0289 H1-4/… 49
10 GO:0034248 regulation… 23/213 165/31… 4.52e-4 0.0290 0.0278 NPM1/… 23
11 GO:0006401 RNA catabo… 16/213 96/3193 4.80e-4 0.0290 0.0278 NPM1/… 16
12 GO:0034250 positive r… 13/213 69/3193 4.89e-4 0.0290 0.0278 NPM1/… 13
13 GO:0051254 positive r… 33/213 276/31… 4.98e-4 0.0290 0.0278 NPM1/… 33
14 GO:0051172 negative r… 47/213 443/31… 5.03e-4 0.0290 0.0278 H1-4/… 47
15 GO:1901798 positive r… 5/213 11/3193 4.18e-4 0.0278 0.0266 DDX5/… 5
# ℹ 1 more variable: negplog <dbl># Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_low, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,5))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = go_enrichment, showCategory = 10, categorySize = "pvalue" )Warning: ggrepel: 44 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)Warning: package 'enrichplot' was built under R version 4.2.1edo <- pairwise_termsim(go_enrichment)
edo#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology BP
#...@keytype SYMBOL
#...@gene chr [1:224] "H1-4" "TUBB3" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "PRDX1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...48 enriched terms found
'data.frame': 48 obs. of 9 variables:
$ ID : chr "GO:0002181" "GO:0006412" "GO:0043043" "GO:0043604" ...
$ Description: chr "cytoplasmic translation" "translation" "peptide biosynthetic process" "amide biosynthetic process" ...
$ GeneRatio : chr "51/213" "71/213" "71/213" "73/213" ...
$ BgRatio : chr "104/3193" "317/3193" "324/3193" "374/3193" ...
$ pvalue : num 2.30e-34 9.36e-23 3.80e-22 1.29e-19 1.57e-19 ...
$ p.adjust : num 5.04e-31 1.03e-19 2.78e-19 6.88e-17 6.88e-17 ...
$ qvalue : num 4.83e-31 9.85e-20 2.67e-19 6.60e-17 6.60e-17 ...
$ geneID : chr "RPL4/RPS3/YBX1/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/YBX3/RPL30"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ ...
$ Count : int 51 71 71 73 40 73 73 34 31 64 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 p1 <- emapplot(edo, showCategory = 30, nCluster = 3)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2Warning: ggrepel: 6 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO Enrichment MF - DE_Pval
go_enrichment <- enrichGO(gene = DE_SYMBOL_Padj,
OrgDb = org.Hs.eg.db,
keyType = "SYMBOL",
universe = Background_SYMBOL,
ont = "MF",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05)
go_enrichment#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology MF
#...@keytype SYMBOL
#...@gene chr [1:224] "H1-4" "TUBB3" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "PRDX1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...13 enriched terms found
'data.frame': 13 obs. of 9 variables:
$ ID : chr "GO:0003735" "GO:0005198" "GO:0003729" "GO:0003724" ...
$ Description: chr "structural constituent of ribosome" "structural molecule activity" "mRNA binding" "RNA helicase activity" ...
$ GeneRatio : chr "50/218" "55/218" "29/218" "12/218" ...
$ BgRatio : chr "129/3240" "303/3240" "155/3240" "33/3240" ...
$ pvalue : num 2.15e-27 6.82e-13 2.11e-07 6.41e-07 6.41e-07 ...
$ p.adjust : num 7.07e-25 1.12e-10 2.31e-05 4.20e-05 4.20e-05 ...
$ qvalue : num 6.55e-25 1.04e-10 2.14e-05 3.90e-05 3.90e-05 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "TUBB3/RPL4/KRT2/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/NUMA1/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30"| __truncated__ "NCL/RPS3/YBX1/DDX5/RPS3A/DDX3X/PABPC1/HNRNPA0/SRRM2/RPS14/PTBP2/PABPC4/SERBP1/G3BP1/YBX3/HDLBP/RPS5/RPL26/RPL24"| __truncated__ "DDX17/DDX5/DDX3X/G3BP1/DDX42/DDX21/DDX50/MTREX/DDX47/DDX18/DDX27/DDX41" ...
$ Count : int 50 55 29 12 12 42 23 26 11 13 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 goplot(go_enrichment, showCategory = 15)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# summary of the result that most people use
plot(barplot(go_enrichment, showCategory = 30 ))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- go_enrichment %>% as_tibble()
GO_Tibble# A tibble: 13 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:000… structural… 50/218 129/32… 2.15e-27 7.07e-25 6.55e-25 RPL4/… 50
2 GO:000… structural… 55/218 303/32… 6.82e-13 1.12e-10 1.04e-10 TUBB3… 55
3 GO:000… mRNA bindi… 29/218 155/32… 2.11e- 7 2.31e- 5 2.14e- 5 NCL/R… 29
4 GO:000… RNA helica… 12/218 33/3240 6.41e- 7 4.20e- 5 3.90e- 5 DDX17… 12
5 GO:000… ATP-depend… 12/218 33/3240 6.41e- 7 4.20e- 5 3.90e- 5 DDX17… 12
6 GO:000… DNA binding 42/218 298/32… 1.38e- 6 7.54e- 5 6.99e- 5 H1-4/… 42
7 GO:014… catalytic … 23/218 124/32… 4.97e- 6 2.33e- 4 2.16e- 4 DDX17… 23
8 GO:014… catalytic … 26/218 172/32… 5.47e- 5 2.24e- 3 2.08e- 3 DDX17… 26
9 GO:001… rRNA bindi… 11/218 42/3240 6.63e- 5 2.29e- 3 2.12e- 3 RPS3/… 11
10 GO:000… helicase a… 13/218 57/3240 6.98e- 5 2.29e- 3 2.12e- 3 DDX17… 13
11 GO:004… mRNA 5'-UT… 7/218 20/3240 2.06e- 4 6.16e- 3 5.71e- 3 NCL/R… 7
12 GO:000… double-str… 19/218 122/32… 3.95e- 4 1.08e- 2 1.00e- 2 H1-4/… 19
13 GO:000… poly(A) bi… 5/218 13/3240 1.08e- 3 2.74e- 2 2.54e- 2 DDX3X… 5# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,60))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = go_enrichment, showCategory = 5, categorySize = "pvalue" )Warning: ggrepel: 2 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)
edo <- pairwise_termsim(go_enrichment)
edo#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology MF
#...@keytype SYMBOL
#...@gene chr [1:224] "H1-4" "TUBB3" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "PRDX1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...13 enriched terms found
'data.frame': 13 obs. of 9 variables:
$ ID : chr "GO:0003735" "GO:0005198" "GO:0003729" "GO:0003724" ...
$ Description: chr "structural constituent of ribosome" "structural molecule activity" "mRNA binding" "RNA helicase activity" ...
$ GeneRatio : chr "50/218" "55/218" "29/218" "12/218" ...
$ BgRatio : chr "129/3240" "303/3240" "155/3240" "33/3240" ...
$ pvalue : num 2.15e-27 6.82e-13 2.11e-07 6.41e-07 6.41e-07 ...
$ p.adjust : num 7.07e-25 1.12e-10 2.31e-05 4.20e-05 4.20e-05 ...
$ qvalue : num 6.55e-25 1.04e-10 2.14e-05 3.90e-05 3.90e-05 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "TUBB3/RPL4/KRT2/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/NUMA1/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30"| __truncated__ "NCL/RPS3/YBX1/DDX5/RPS3A/DDX3X/PABPC1/HNRNPA0/SRRM2/RPS14/PTBP2/PABPC4/SERBP1/G3BP1/YBX3/HDLBP/RPS5/RPL26/RPL24"| __truncated__ "DDX17/DDX5/DDX3X/G3BP1/DDX42/DDX21/DDX50/MTREX/DDX47/DDX18/DDX27/DDX41" ...
$ Count : int 50 55 29 12 12 42 23 26 11 13 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 p1 <- emapplot(edo, showCategory = 15, nCluster = 3)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO Enrichment CC - DE_Pval
go_enrichment <- enrichGO(gene = DE_SYMBOL_Padj,
OrgDb = org.Hs.eg.db,
keyType = "SYMBOL",
universe = Background_SYMBOL,
ont = "CC",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05)
go_enrichment#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology CC
#...@keytype SYMBOL
#...@gene chr [1:224] "H1-4" "TUBB3" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "PRDX1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...26 enriched terms found
'data.frame': 26 obs. of 9 variables:
$ ID : chr "GO:0022626" "GO:1990904" "GO:0044391" "GO:0005840" ...
$ Description: chr "cytosolic ribosome" "ribonucleoprotein complex" "ribosomal subunit" "ribosome" ...
$ GeneRatio : chr "48/220" "82/220" "51/220" "52/220" ...
$ BgRatio : chr "78/3284" "367/3284" "141/3284" "155/3284" ...
$ pvalue : num 1.69e-38 2.23e-26 2.47e-26 4.79e-25 1.10e-19 ...
$ p.adjust : num 5.52e-36 2.69e-24 2.69e-24 3.91e-23 7.19e-18 ...
$ qvalue : num 4.97e-36 2.42e-24 2.42e-24 3.52e-23 6.48e-18 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "NPM1/NCL/RPL4/DDX17/RACK1/RPS3/YBX1/DDX5/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/SRRM2/RPS14/NOP58/RPS18/R"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ ...
$ Count : int 48 82 51 52 25 23 25 49 26 16 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 # Go plot
goplot(go_enrichment, showCategory = 25)Warning: ggrepel: 4 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# summary of the result that most people use
plot(barplot(go_enrichment, showCategory = 25))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- go_enrichment %>% as_tibble()
GO_Tibble# A tibble: 26 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:002… cytosolic … 48/220 78/3284 1.69e-38 5.52e-36 4.97e-36 RPL4/… 48
2 GO:199… ribonucleo… 82/220 367/32… 2.23e-26 2.69e-24 2.42e-24 NPM1/… 82
3 GO:004… ribosomal … 51/220 141/32… 2.47e-26 2.69e-24 2.42e-24 RPL4/… 51
4 GO:000… ribosome 52/220 155/32… 4.79e-25 3.91e-23 3.52e-23 RPL4/… 52
5 GO:002… cytosolic … 25/220 42/3284 1.10e-19 7.19e-18 6.48e-18 RPL4/… 25
6 GO:002… cytosolic … 23/220 36/3284 3.48e-19 1.89e-17 1.70e-17 RPS3/… 23
7 GO:001… small ribo… 25/220 58/3284 2.91e-15 1.36e-13 1.22e-13 RACK1… 25
8 GO:000… nucleolus 49/220 262/32… 4.72e-12 1.92e-10 1.73e-10 NPM1/… 49
9 GO:001… large ribo… 26/220 84/3284 7.92e-12 2.87e-10 2.59e-10 RPL4/… 26
10 GO:000… polysome 16/220 41/3284 2.21e- 9 7.21e- 8 6.50e- 8 RPS3/… 16
# ℹ 16 more rows# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,90))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = go_enrichment, showCategory = 5, categorySize = "pvalue" )
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)
edo <- pairwise_termsim(go_enrichment)
edo#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology CC
#...@keytype SYMBOL
#...@gene chr [1:224] "H1-4" "TUBB3" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "PRDX1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...26 enriched terms found
'data.frame': 26 obs. of 9 variables:
$ ID : chr "GO:0022626" "GO:1990904" "GO:0044391" "GO:0005840" ...
$ Description: chr "cytosolic ribosome" "ribonucleoprotein complex" "ribosomal subunit" "ribosome" ...
$ GeneRatio : chr "48/220" "82/220" "51/220" "52/220" ...
$ BgRatio : chr "78/3284" "367/3284" "141/3284" "155/3284" ...
$ pvalue : num 1.69e-38 2.23e-26 2.47e-26 4.79e-25 1.10e-19 ...
$ p.adjust : num 5.52e-36 2.69e-24 2.69e-24 3.91e-23 7.19e-18 ...
$ qvalue : num 4.97e-36 2.42e-24 2.42e-24 3.52e-23 6.48e-18 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "NPM1/NCL/RPL4/DDX17/RACK1/RPS3/YBX1/DDX5/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/SRRM2/RPS14/NOP58/RPS18/R"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ ...
$ Count : int 48 82 51 52 25 23 25 49 26 16 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 p1 <- emapplot(edo, showCategory = 15, nCluster = 3)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Enrichment Test Wrangle Downregulated DE genes
# 1. Read in the comprehensive DF that contains all sample info
Full_DF %>% head() Entrez.Gene.ID Ensembl.Gene.ID Gene.Symbol Accession
1 4625 ENSG00000092054 MYH7 P12883
2 4624 ENSG00000197616 MYH6 P13533
3 7273 ENSG00000155657 TTN Q8WZ42
4 70 ENSG00000159251 ACTC1 P68032
5 58 ENSG00000143632 ACTA1 P68133
6 60 ENSG00000075624 ACTB P60709
Abundance..F1..Sample..Dox..n.a Abundance..F3..Sample..Dox..n.a
1 5.25e+10 7.41e+10
2 1.00e+09 1.47e+09
3 1.39e+10 2.08e+10
4 3.92e+10 4.11e+10
5 1.72e+07 5.81e+07
6 4.02e+09 8.43e+08
Abundance..F5..Sample..Dox..Dox Abundance..F7..Sample..Dox..Dox
1 5.28e+10 6.82e+10
2 5.11e+09 4.25e+09
3 2.19e+10 2.49e+10
4 3.76e+10 3.54e+10
5 3.85e+07 5.07e+07
6 2.04e+09 1.62e+09
Abundance..F9..Sample..Dox..Dox Abundance..F2..Control..Veh..n.a
1 6.43e+10 4.33e+10
2 2.62e+09 1.50e+09
3 2.34e+10 1.29e+10
4 3.69e+10 3.54e+10
5 6.19e+07 1.64e+07
6 1.61e+09 4.16e+09
Abundance..F4..Control..Veh..n.a Abundance..F6..Control..Veh..Veh
1 7.41e+10 7.00e+10
2 1.17e+09 2.42e+09
3 2.25e+10 2.52e+10
4 2.96e+10 3.56e+10
5 3.44e+07 5.42e+07
6 6.45e+08 1.92e+09
Abundance..F8..Control..Veh..Veh Abundance..F10..Control..Veh..Veh
1 5.64e+10 5.26e+10
2 3.67e+09 3.27e+09
3 2.46e+10 2.21e+10
4 2.98e+10 2.91e+10
5 3.36e+07 4.05e+07
6 1.81e+09 1.56e+09toptable_Threshold_0.05$logFC [1] -3.5538167761 -2.1410928975 -1.6342957224 -4.3423803749 -1.1658966201
[6] -1.7622803092 -2.1096892264 2.3724491682 -1.1425406345 -2.1455298252
[11] -0.8019789647 -1.1045436713 -2.2554253126 0.7861550384 1.3614453777
[16] -1.0858313049 -0.7539368895 -0.7752299178 -0.7435322555 -2.3955560537
[21] -0.9058215272 -1.1338838135 -1.6536207267 -1.2192370415 -0.7674689571
[26] -0.7632109180 -1.0206069551 -1.2083869980 1.7059490390 1.1382005458
[31] -1.5081799250 -1.5653815562 -1.8797159229 -1.2351650877 -0.7285835498
[36] -2.6174073619 -1.0158315089 -1.4794349461 -0.7979336434 -2.7782295557
[41] -0.6448869669 -0.6951266140 0.5742911993 1.2393881736 -0.7134418171
[46] 0.6514755296 0.7026843452 -0.7576536433 0.9639278116 -1.6242843304
[51] -1.4507298032 -0.9477995132 -0.7460068993 -0.9617635928 -0.6128746798
[56] -1.7373368214 -1.1157407297 -1.1141546927 -1.0743673769 0.8520902429
[61] 1.1594641852 -1.7454620125 -0.6301099885 -1.5769850831 -0.7268629014
[66] 0.7708229050 0.7405558040 -0.5903700138 -0.8072247663 -0.8148623788
[71] 0.7768860215 0.9093433795 -0.6371784527 -0.5116069160 -1.8332257421
[76] -0.7266249638 0.8163123746 -1.0153940278 -0.6669134126 -0.9054903012
[81] -0.6059548196 -0.5729549732 0.6126517330 -0.4568522015 -0.6160229343
[86] -1.1986896135 1.6934062614 -0.9596894143 1.6001832065 -0.9044508349
[91] -0.7250445918 -0.8540143136 -0.6967076722 -0.4757964569 -0.9888508824
[96] -0.5172166796 1.0062251308 -0.6906765081 -0.5251120289 0.5208548082
[101] 1.2411170961 -0.5882082097 0.7849629140 -0.6777723393 -0.6026084568
[106] -0.5031254586 0.5589429736 0.5788276899 -0.5543597613 -0.6667823795
[111] -0.5878505606 -1.1241955717 -1.6006476533 -0.7779107967 -1.1116578520
[116] -1.0789245230 0.5414058709 -1.0074850656 0.5800084020 -0.7844961130
[121] 0.5174185908 -0.6427814586 -0.8002218256 -1.0084011844 -2.3190460799
[126] -0.7025333738 -0.4629932812 -0.6501491349 -0.4807151241 1.3983624382
[131] -0.6722019865 -0.5803803999 -1.3991428488 -0.4794151940 0.4642899702
[136] -0.5670129678 -0.5872810025 -0.7368335650 -0.6721264871 -0.7035432539
[141] -0.5256142728 -0.9494860176 -1.4597652645 -0.5290939081 -1.0838816024
[146] -0.4880244806 -0.8329828638 -2.4632413096 -1.0476033013 -0.4397303828
[151] -0.6838448301 -0.4109111435 -1.3241873915 -1.6821249628 -0.9432339010
[156] -1.1211381976 -1.0117994714 -0.5044680663 0.7271212659 -1.6985247921
[161] -0.6622600305 -0.5606924342 -1.2591913827 -1.3635409111 -0.4467117211
[166] -1.4130213235 -0.4297886272 0.5376047849 -1.6471304981 -0.4220855821
[171] -0.5392572756 -1.6782527965 -1.0063252056 -0.8070167308 -1.2890200440
[176] -0.4759712554 -0.5580530118 1.6055961679 -0.8936118551 -0.8083854490
[181] -0.4444226909 -1.0547820892 -0.9746307783 -0.4428959494 -0.5710654747
[186] -0.4925725531 -0.4080247904 -1.0350132316 -0.5908648570 -0.5203788401
[191] -0.7958276532 -0.7746361337 0.7104695951 0.5548415064 -0.5964048840
[196] 0.6415744071 0.5151478042 -0.5207857144 -1.4394805400 -0.4287029276
[201] -2.5438450163 -1.1179694119 -0.7887611969 -0.5416817723 -0.6991609801
[206] -0.4169526676 -0.7789476428 -0.4298640795 -0.7914407893 -0.8915834740
[211] -0.4642474623 -0.3899063239 -1.7898291377 -0.9057750747 -0.7050242947
[216] 0.6888824932 0.4997938598 -0.4084318083 -0.4153614928 -0.4156445083
[221] -2.2499176112 -0.4399589985 0.6223084191 -0.6951469188 -0.3563229842
[226] -0.4142764701 0.4469205277 0.6298863463 -0.5274168749 -0.7572117675
[231] -0.7414080073 0.5931696188 -0.5645815732 -0.5239525168 -0.4730751821
[236] -0.4014406815 -0.8551857038 0.3371940543 -1.0496574340 -0.4052133229
[241] -0.4028447239 -0.5503947248 -1.3454650365 -0.7178325605 0.8584113427
[246] -0.8109774106 0.4303957377 -0.3870496758 0.6227885873 0.6197817327
[251] -0.5852458646 -1.7305546971 -0.3987696346 -0.6067669038 -0.4920832708
[256] -1.6245155473 -0.4647297615 -0.6965710684 -1.3849747643 -0.9055782502
[261] -0.3767310091 -0.8768551571 -0.4686270379 -0.6511987136 -0.8124911955
[266] -1.0233266627 -0.4358097247 0.4659275185 1.1347468039 -0.4517640243
[271] -1.3304992746 -1.2928101198 -1.4343007477 0.4790130748 -0.6339303010
[276] -0.3894487283 -0.7810261501 -0.4206857485 0.3113855959 -0.6528927231
[281] -2.5854233520 -0.8721945896 -0.6729555239 -0.6445959769 -0.3456255710
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[1316] 0.1913990895 -0.1797804518 -0.2296707827 -0.9140598966 0.1822936202
[1321] 0.1957930676 0.2536459915 -0.8492074981 -0.1956753243 0.2971402877
[1326] 0.3103938096 -0.8965424131 0.1737179212 0.1451491849 0.2278769792
[1331] 0.3041902391 0.4748070915 1.1789486526 -0.2413307076 0.3817066867
[1336] -0.2240857927 -0.3024427746 0.1810344084 0.2368755761 -0.4018363757
[1341] 0.2277610361 0.1921134483 0.1966753339 0.2119918562 0.1752998970
[1346] -0.3937373400 -0.4266921252 -0.4769448034 -0.4092360678 0.3734020518
[1351] -0.2499214918 -0.2132298260 -0.1458601456 -0.5391192012 0.1856541714
[1356] -0.1551044830 0.1997982639 -0.2083323637 0.1756689741 0.1734064100
[1361] -0.1526553555 -0.5116488542 0.1847757544 0.1760794914 0.1839611026
[1366] -0.1437019702 0.1691107558 0.2558898146 0.1995929713 0.2918815492
[1371] 0.3293744375 -0.2557982811 -0.1770725141 0.2414028600 0.1818020732
[1376] -0.1886612531 0.5602075722 -0.4337233743 0.2168163302 0.3238087856
[1381] -0.2846316844 0.1774794224 -0.2497138415 0.1660316066 -0.4270998235
[1386] -0.1545494103 -0.2038991202 -0.4545700983 0.2446095314 0.1711955194
[1391] -0.7257889002 0.1577193899 0.1880983245 -0.2396861754 -0.1866335481
[1396] -0.1763420126 0.1934172414 0.3305181281 0.1517306753 -0.1703746942
[1401] 0.2133141718 -0.4304415165 0.2595738896 0.3537433291 0.3625873956
[1406] -0.1526359695 -0.1340646006 -0.2727849206 -0.4039064278 -0.2213488910
[1411] -0.1924487788 0.1806870857 0.1528159549 0.1633911931 0.2470100373
[1416] 0.1445148178 0.2014163689 -0.2018248668 -0.1669144692 0.1658497680
[1421] -0.3627875751 -0.3198460718 0.3306605987 0.1495701720 -0.2588645770
[1426] 0.2740878873 0.1375474911 0.1356290773 -0.4179321655 0.1834502649
[1431] -0.3242395030 0.1934506828 -0.1489503500 -0.1696430939 -0.3774227433
[1436] 0.7947308803 0.1385605348 0.3123543318 -0.2202004135 0.3338440517
[1441] -0.1676191426 0.7666161069 0.2066317185 0.3573558785 -0.2046992466
[1446] 0.3757262075 0.1525930061 -0.1779168350 -0.2013385424 0.2054883472
[1451] -0.2038856728 -0.2177406623 0.4556479812 -0.2048633444 -0.2219309686
[1456] 0.3214946498 -0.5551680429 -0.3932751306 -0.3026347170 -0.2319046639
[1461] 0.1249858773 0.1931230260 0.2922302106 0.1912003732 -0.2269443773
[1466] -0.3948449302 0.1947359574 -0.1828645648 0.1944969932 0.1739632470
[1471] 0.1706370371 0.1276870681 -0.2347226597 0.4119754421 0.1399504432
[1476] -0.3457421561 -0.3769303003 0.2069007037 0.1787571873 0.9020558768
[1481] 0.1442489499 0.4065555948 -0.1146413565 0.3819258261 0.1423087293
[1486] 0.1300332666 -0.1714179530 0.1695546343 0.1696781285 -0.4241305396
[1491] -0.3499586745 -0.1219694750 0.1345680756 0.5645834417 0.1722444477
[1496] 0.2143259695 -0.2366917099 -0.1586315023 0.2203412051 0.1568730927
[1501] 0.5294558186 -0.2400599582 0.2606131025 -0.2814472256 -0.2069838669
[1506] 0.2251423360 0.4097285533 0.1599648738 -0.3531608424 0.3374283381
[1511] -0.2735823428 -0.1783913409 0.1479036002 -0.5672004033 0.1833158546
[1516] -0.3781307178 0.1634320972 0.5412345970 0.1539244082 -0.4168327023
[1521] -0.2644762835 -0.3183726759 -0.1748212375 0.2042071532 0.2946458440
[1526] -0.3615133076 -0.3990717083 0.1511876257 0.2589337745 0.4247578463
[1531] 0.1583752804 -0.1708557213 -0.1314736851 -0.1640100525 0.1897139185
[1536] -0.3547290681 0.2123020967 -0.1497285352 0.6251707481 0.1829728813
[1541] -0.1826969056 0.1387678869 0.1354217771 0.1356042458 -0.2163136486
[1546] -0.2935051522 -0.1997517294 -0.1478656322 -0.1697867618 0.2232652366
[1551] 0.3592277349 0.1578093580 -0.2733087334 -0.2662306396 -0.4203079802
[1556] 1.1206318431 0.2279536937 -0.5884289392 -0.1922496341 0.2049176888
[1561] -0.4192457029 0.2575344642 0.1403036475 0.3828737024 0.3718952595
[1566] -1.1748616520 -0.6064984163 -0.1875597915 -0.2649749515 0.1404295768
[1571] 0.1265583997 0.2768460770 0.4084989557 0.2323694291 0.1578526585
[1576] 0.2626134284 0.3199039862 0.4211300832 0.1530751873 -0.3112330991
[1581] 0.1964298987 -0.5581871743 0.3567904027 -0.3380675936 -0.2131864988
[1586] 0.2773729555 -0.2944864528 0.2153007426 0.3219863805 0.2193858814
[1591] -0.2213285426 0.2510442243 0.3483369572 0.2295284048 0.2707294449
[1596] -0.3737205849 0.1844702112 0.1747237411 0.1266610913 0.1263343407
[1601] 0.2403507390 -0.1642694784 0.1989696848 -0.2152424473 -0.2024959410
[1606] -0.1869593310 1.2569154842 -0.1655102239 -0.1225704779 -0.1627755026
[1611] 0.2459319442 -0.2140915439 0.4440944221 0.2499658609 -0.6322504970
[1616] 0.2034250198 -0.4131167536 -0.2629063161 -0.1619819506 0.2781767762
[1621] 0.1717452486 0.2640393362 -0.1393212043 -0.1896560845 -0.4584078011
[1626] -0.1919268814 0.1731613968 0.2032373336 -0.1482501119 0.2038126527
[1631] 0.1418524862 -0.3138206338 0.2264951318 0.7614004148 -0.3401007616
[1636] 0.1456566581 0.1394492596 0.1794882687 -0.3284056844 0.2102243181
[1641] -0.2150802840 -0.1386995442 -0.2023316616 0.1846416190 -0.6193118089
[1646] 0.1698605945 0.3079448969 -0.2046320465 -0.3711372142 -0.2456349172
[1651] 0.4518592849 0.3456520334 -0.3590790930 0.3567368899 -0.1424573779
[1656] 0.2489579868 0.1291995546 0.1798371745 0.1435524358 0.2512525141
[1661] 0.2029690883 0.2087570688 0.1177502284 0.1844768679 0.1132188809
[1666] 1.0994459896 0.3947110352 0.2121736850 0.3820621333 -0.1892167283
[1671] -0.3073166158 0.1358267045 0.2948039564 -0.1519854196 0.2677206428
[1676] -0.1276894010 0.2814176576 -0.1994485307 -0.3853440432 0.3108440907
[1681] -0.4057918444 0.1885129287 -0.1489839924 0.1786945349 -0.2172233972
[1686] 0.2628487810 0.1329728029 0.3291979286 0.2808150998 -0.2341272132
[1691] 0.5482526245 0.1505143852 -0.1543210621 0.1759483154 -0.7229710435
[1696] 0.2328552920 0.3363279060 0.3862971555 0.1505975124 -0.1259800264
[1701] 0.1547902954 0.2036752498 0.7971485090 0.1516371828 -0.6404741507
[1706] 0.5196648792 -0.2664545546 0.1786214258 0.1428261347 0.1536044680
[1711] -0.1134483301 -0.1601107142 0.6135109749 -0.2476196549 -0.2443833248
[1716] 0.2679061725 0.2119346831 0.1232137170 -0.3149054734 0.2208384406
[1721] 0.1939024144 0.1227043825 0.5400156682 0.3560863340 -0.1487258718
[1726] 0.2220605490 -0.1799037193 0.1967298835 -0.1402372840 0.1946472071
[1731] 0.2543600134 0.2361853690 -0.1210626053 -0.1177464463 -0.1476165330
[1736] 0.2606785320 0.1399809919 0.1865845426 0.1493853231 -0.2555945521
[1741] 0.2520398057 0.2996196471 0.1479163298 0.2057463484 0.2825310123
[1746] 0.2640968158 0.1977423568 0.3122123183 0.1232028947 0.1615035994
[1751] 0.1381457962 -0.3556283888 0.1082411643 -0.3288842935 0.1236782127
[1756] -0.2252215300 0.1223331444 -0.2449752601 -0.1378927305 0.1878757736
[1761] -0.2704909154 0.1065416788 -0.2231393848 0.1686627684 0.2273542608
[1766] 0.1815756870 0.1263945529 -0.2019461981 0.1211254836 0.1356243660
[1771] 0.3021874813 -0.3342276775 0.1508902709 0.8137557802 0.1385010702
[1776] 0.1850543583 -0.1377394502 -0.4215543822 0.2098903285 0.1124389846
[1781] -0.3579173999 0.1740427263 0.2193683417 -0.1422236499 -0.1238886474
[1786] 0.1100212785 -0.5201741173 -0.1613273299 -0.1687411465 -0.2654249140
[1791] 0.4371709366 0.3161051930 0.2641095507 -0.2964064156 0.2449748418
[1796] -0.2071578184 -0.3047021024 0.1812734486 0.2028367121 0.7374886596
[1801] -0.3042980713 0.1604490806 0.1199150173 -0.1794847801 0.1198959270
[1806] -0.3647429847 0.1669020284 0.2287939484 0.1856459077 -0.2037149376
[1811] 0.1680862376 -0.4786288291 0.1936065215 0.2431381295 0.1197831916
[1816] -0.1928366990 -0.2896384659 -0.1847857949 -0.2268731958 0.3351063565
[1821] 0.7262850014 0.1193456952 -0.1856868209 0.1411615606 -0.4361139557
[1826] 0.1435746546 -0.4121759213 0.1950751068 -0.1774755759 -0.2440525252
[1831] 0.1290881568 -0.2845034110 0.2868523980 -0.1521050477 0.1508234778
[1836] 0.2021339246 0.1502564030 0.2424868192 0.1045821854 -0.5027216185
[1841] -0.1676507132 0.1540476330 -0.3214679156 -0.2352245268 0.2760268696
[1846] 0.5918018898 -0.5086292319 -0.1264495797 0.1013530396 -0.2299422577
[1851] 0.1600876037 0.1448143904 -0.1459837821 0.1708269618 -0.1106735179
[1856] -0.1393551959 -0.2332978096 0.1911236098 0.3656204165 0.1855972361
[1861] -0.5961135139 -0.3925170994 0.5855252691 0.1064003350 0.1318888957
[1866] 0.1280641474 -0.3903692553 -0.1533700029 0.2387106959 0.2206874894
[1871] 0.2277853536 0.1937722354 0.1988457745 -0.1098624407 0.1386420303
[1876] -0.1166498631 0.1402020249 0.2084939460 0.1059867484 -0.1379744633
[1881] 0.2027328807 0.3971986235 -0.2263056092 -0.1556871183 0.2624877482
[1886] 0.5482295030 -0.3398549778 0.1059117284 0.1865763781 0.1104266196
[1891] -0.1175481021 0.1406275506 -0.1100540659 0.1996727921 -0.3830711095
[1896] 0.1497891845 0.2127646086 0.0989970306 -0.2416044788 -0.3289073428
[1901] 0.5362827661 -0.1937537190 0.1130945858 0.2743177664 -0.1302150180
[1906] -0.1023378975 0.1674143768 0.2266581825 0.1456591584 0.1656514288
[1911] 0.1573491429 -0.1081806014 0.3007788675 0.1806922599 0.1675754927
[1916] 0.1608435877 0.3453116664 -0.1624602228 0.2110096754 -0.1172680589
[1921] 0.1427424435 0.1554968850 0.1152187935 0.1341858302 -0.2120833022
[1926] 0.1786406642 0.2571098478 0.1291873526 -0.3272065357 0.1168814392
[1931] 0.1108361099 0.1384347078 -0.1891713554 0.1551579680 0.1939043677
[1936] 0.1413990622 -0.1258222035 -0.1781832359 -0.3029357093 -0.4181034357
[1941] -0.3972969266 -0.1025116264 -0.1189350733 0.1600657958 0.3644860585
[1946] -0.1733205454 -0.3338646105 -0.2296435722 0.2380869581 -0.3228400161
[1951] 0.1405542089 0.1356121218 -0.2309149387 -0.2270881915 -0.0908786821
[1956] 0.1964047121 0.1164590731 -0.2221418710 0.1019734385 -0.1438827917
[1961] -0.1376909006 -0.2391865419 0.1246305850 0.1253233305 0.5291243342
[1966] 0.1794061749 0.1341115999 -0.2935734855 0.1232787774 -0.3479027395
[1971] -0.4244074996 0.1438558273 -0.1716659061 0.1732072375 0.0911141711
[1976] -0.1555959272 0.1463125698 -0.1277078100 0.2111877176 -0.3509102066
[1981] 0.4736180211 -0.2906977060 0.1587803118 0.2827424002 0.1346303030
[1986] -0.1327156417 -0.1526145948 0.1546073095 0.1528123888 -0.0969674495
[1991] 0.1297635336 0.1195975287 -0.1419630652 0.1826309791 0.1393937256
[1996] 0.1471579924 -0.2051732977 -0.1402833892 0.1720986788 0.1091842804
[2001] -0.3145349692 -0.1829436373 0.1620047804 0.2956679206 0.1035594132
[2006] -0.1389552255 0.1635104108 0.0926078408 -0.1469129728 0.1665853652
[2011] -0.1012366081 -0.0919919405 0.2428422205 -0.1873734274 0.1335478206
[2016] 0.1240278652 -0.1369132601 0.1980879304 -0.0920412487 0.2525084456
[2021] 0.1092616396 0.1195647718 0.1754433704 -0.1603465862 0.4607441303
[2026] 0.3602161255 -0.2937040729 0.1293255070 -1.1688527044 0.1228670487
[2031] -0.2945009993 -0.6650784565 0.1273674588 0.1601022524 -0.6319949280
[2036] 0.1491572499 -0.1672168492 0.1139328640 -0.1942462621 -0.1330187061
[2041] 0.2060868424 -0.1160366021 -0.0944147087 0.1359207349 -0.1377189249
[2046] 0.0939589999 0.1043407372 -0.1052286710 -0.1539773030 0.1337896782
[2051] -0.2536091609 0.1093543052 0.1431320158 0.1687013129 0.1572445637
[2056] 0.0848902434 0.1053534927 -0.1798585110 -0.1852202414 -0.2282349511
[2061] -0.1331274024 -0.1503714294 -0.0941274403 -0.1582100924 -0.1223646655
[2066] -0.2788674167 -0.2009798037 -0.1642863515 0.2517651870 -0.1189895730
[2071] -0.1132828115 0.1344889029 0.2632308677 -0.2839601305 0.3238208798
[2076] -0.1809043530 -0.1079442040 -0.0919210459 -0.1385477506 0.1402636759
[2081] -0.1082147945 0.1060104999 -0.3300467973 -0.2176380759 0.5124778155
[2086] 0.1396464367 0.1849873854 -0.1161368344 0.1841135011 0.1132479572
[2091] -0.1097208441 -0.2216553149 0.1348035251 0.2356284579 0.1552915531
[2096] 0.2229599558 -0.1129805033 0.1839253515 0.1175729384 -0.5603799007
[2101] 0.1192798867 0.2850250352 -0.1177878913 -0.1306215778 -0.3068203340
[2106] -0.1089420401 -0.2140358593 0.1066922979 0.1173837438 0.1281586003
[2111] -0.1559450159 -0.1024336555 -0.1611255677 0.1072285522 -0.0970143479
[2116] 0.0980933538 -0.1054766979 0.1185292661 -0.0837789331 0.1264718437
[2121] 0.0791359883 -0.1178194013 0.3991605464 0.1854485602 -0.1693795768
[2126] 0.1613657814 -0.0989629001 0.0902401783 0.2260558350 -0.1457402759
[2131] 0.0966267844 0.3826193809 -0.2439902363 -0.2897704100 0.1213932177
[2136] -0.1253172696 -0.2943213697 0.3756555127 0.2582655819 -0.1875987929
[2141] 0.2295703517 -0.1032980210 -0.2791393242 0.0926776020 -0.1106006243
[2146] 0.0995037586 -0.2318329234 0.1751096875 -0.1321410744 -0.1501626685
[2151] -0.0999382249 0.1961702509 0.1243371284 -0.2665467709 -0.4385883218
[2156] 0.1304443104 -0.1065776955 -0.1614489475 -0.2719364230 -0.3388657821
[2161] 0.0981272779 0.2328756144 -0.2799289032 -0.1735731130 -0.4929113011
[2166] -0.0922032534 -0.2779636141 -0.2734504237 0.4497415915 -0.1073078980
[2171] -0.1876504937 0.2062944598 -0.1898250821 -0.1685498276 0.1044799417
[2176] 0.0999937434 0.0935948268 -0.3013653463 0.2822536255 -0.3061198829
[2181] 0.0752190673 0.1644296131 -0.1573011749 0.2551237886 0.3789248124
[2186] 0.0946360809 0.1547593964 0.1457073318 -0.1786974852 -0.1012872358
[2191] 0.1174575184 0.1087991394 0.1294518467 -0.1804230458 -0.1753460633
[2196] 0.6861820167 0.1918283846 0.1414397274 0.0846556240 -0.2659856053
[2201] -0.2355238688 -0.1159312603 0.2095158169 -0.4157903448 -0.1113749380
[2206] 0.1161351290 -0.2726417501 0.1210246679 0.0848442530 0.1034871730
[2211] 0.2476201453 -0.1575405030 -0.2838945881 -0.2687302665 0.1980954870
[2216] -0.1693895431 -0.1423709405 0.1023200639 -0.2184100347 0.1576033040
[2221] 0.1632916359 0.1021725140 0.1057716482 -0.0739419192 -0.0941046311
[2226] 0.5567733277 0.1188716514 0.1341548659 -0.1014993198 0.0920632675
[2231] 0.0830265367 0.1178529959 0.1087674664 0.2768044646 -0.1314082211
[2236] -0.1219872828 0.1056491090 -0.1283539466 -0.1003376983 -0.1057187487
[2241] -0.2140228002 0.1189427241 -0.2088961218 0.0962979309 -0.1976599575
[2246] 0.1094022386 -0.1357862654 0.1462977043 0.5165688842 0.1188448055
[2251] 0.1329451073 -0.2378256940 0.0963912099 0.1398682501 0.0859174106
[2256] 0.0973916468 0.3294577858 -0.1035949163 -0.1058417568 0.1094297534
[2261] 0.1196860011 -0.1721965292 0.2358430178 -0.3650271906 0.0918088877
[2266] -0.0812919777 0.0907640999 -0.2000855117 -0.2336430828 -0.0752068166
[2271] 0.1207502672 0.2147703958 -0.2833920949 0.0980445736 -0.1536421186
[2276] -0.4297291464 0.0737346295 0.1734007188 0.1117955619 0.1205849581
[2281] -0.3207193545 -0.1548600142 0.1639074520 0.1203514909 -0.1280768636
[2286] -0.1416605055 -0.1113613082 -0.1098357922 -0.3189583107 0.1608753759
[2291] 0.1680761578 0.0870007334 0.0715412654 -0.1374402276 -0.0845387504
[2296] -0.1310341467 0.2875435215 -0.3582403310 -0.2992525080 -0.1013794478
[2301] 0.1245090072 0.1169775237 0.1039484149 -0.3775847726 -0.1260903235
[2306] -0.1210657317 0.0870340184 -0.0882905799 -0.0830500422 0.2486727601
[2311] 0.1624464050 0.0729566441 0.1523180829 -0.2017070163 0.1134130640
[2316] 0.1109538226 0.1068054840 -0.0960413079 -0.2673945504 0.0873761706
[2321] -0.5314522470 -0.1006003504 0.0940390925 0.1086948704 -0.0847909552
[2326] -0.1095230216 0.0804018831 -0.0892285079 0.0858122234 0.1126757023
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[3361] -0.0035464856 0.0039575492 0.0085658006 0.0024531736 -0.0030229107
[3366] -0.0035448747 0.0018041193 -0.0045005530 0.0015316464 0.0013072005
[3371] 0.0021581420 0.0050398203 -0.0015175385 -0.0013230822 0.0037181052
[3376] 0.0008048923 0.0012681861 0.0012070742 0.0006074187 -0.0006529423
[3381] 0.0002573516 -0.0002124377 -0.0003543919 -0.0002160733# 2.
# Get set of DE proteins as per BH adjusted P-value
DE_proteins_Padj <- toptable_Threshold_0.05 %>%
filter((logFC < 0) & (adj.P.Val < 0.05)) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% DE_proteins_Padj)
# Subset the data frame
subset_Full_data <- Full_DF[rows, ]
# Here are the SYMBOL IDs for the DE proteins as per BH adj P value < 0.05
DE_SYMBOL_Padj <- subset_Full_data$Gene.Symbol %>% unique() %>% na.omit()
# Get background Symbol IDs
All_proteins_tested <- toptable_Threshold_0.05 %>%
filter(adj.P.Val < 1) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% All_proteins_tested)
# Subset the data frame
subset_back_data <- Full_DF[rows, ]
Background_SYMBOL <- subset_back_data$Gene.Symbol %>% unique() %>% na.omit() GO Enrichment BP - Downregulated Genes
# 1.
# Do enrichment analysis of ENTREZ IDs from Padjusted value
# Perform GO enrichment analysis using the enrichGO function. We are using stringent cutoffs for Pvalue and q value in the testing! (this is good)
go_enrichment <- enrichGO(gene = DE_SYMBOL_Padj,
OrgDb = org.Hs.eg.db,
keyType = "SYMBOL",
universe = Background_SYMBOL,
ont = "BP",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05)
go_enrichment#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology BP
#...@keytype SYMBOL
#...@gene chr [1:183] "H1-4" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "DDX17" "RACK1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...74 enriched terms found
'data.frame': 74 obs. of 9 variables:
$ ID : chr "GO:0002181" "GO:0006412" "GO:0043043" "GO:0043604" ...
$ Description: chr "cytoplasmic translation" "translation" "peptide biosynthetic process" "amide biosynthetic process" ...
$ GeneRatio : chr "51/172" "70/172" "70/172" "71/172" ...
$ BgRatio : chr "104/3193" "317/3193" "324/3193" "374/3193" ...
$ pvalue : num 1.51e-39 1.39e-28 6.09e-28 1.18e-24 3.36e-23 ...
$ p.adjust : num 2.99e-36 1.38e-25 4.02e-25 5.86e-22 1.33e-20 ...
$ qvalue : num 2.84e-36 1.31e-25 3.81e-25 5.56e-22 1.26e-20 ...
$ geneID : chr "RPL4/RPS3/YBX1/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/YBX3/RPL30"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ ...
$ Count : int 51 70 70 71 70 71 38 61 71 29 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 # Go plot
goplot(x = go_enrichment, showCategory = 20)Warning: ggrepel: 32 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# summary of the result that most people use
plot(barplot(go_enrichment, showCategory = 20))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- go_enrichment %>% as_tibble()
GO_Tibble# A tibble: 74 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:000… cytoplasmi… 51/172 104/31… 1.51e-39 2.99e-36 2.84e-36 RPL4/… 51
2 GO:000… translation 70/172 317/31… 1.39e-28 1.38e-25 1.31e-25 NPM1/… 70
3 GO:004… peptide bi… 70/172 324/31… 6.09e-28 4.02e-25 3.81e-25 NPM1/… 70
4 GO:004… amide bios… 71/172 374/31… 1.18e-24 5.86e-22 5.56e-22 NPM1/… 71
5 GO:000… peptide me… 70/172 383/31… 3.36e-23 1.33e-20 1.26e-20 NPM1/… 70
6 GO:003… cellular m… 71/172 407/31… 2.70e-22 8.91e-20 8.45e-20 NPM1/… 71
7 GO:004… ribosome b… 38/172 118/31… 3.79e-21 1.07e-18 1.02e-18 NPM1/… 38
8 GO:000… RNA proces… 61/172 356/31… 2.36e-18 5.85e-16 5.55e-16 NCL/D… 61
9 GO:004… cellular a… 71/172 475/31… 3.46e-18 7.61e-16 7.22e-16 NPM1/… 71
10 GO:000… rRNA proce… 29/172 85/3193 5.42e-17 1.07e-14 1.02e-14 DDX17… 29
# ℹ 64 more rows# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biologcal Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,100))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO_Tibble$negplog <- -log(GO_Tibble$p.adjust)
# Break up into high, medium and low siignfigance groups
# 1. High
# Create a sample data frame
GO_Tibble_Upper <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 67
upper_percentile <- 100
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Upper <- GO_Tibble_Upper[GO_Tibble_Upper$negplog >= lower_value & GO_Tibble_Upper$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Upper, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0, 90))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. Med
# Create a sample data frame
GO_Tibble_Mid <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 33
upper_percentile <- 67
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Mid <- GO_Tibble_Mid[GO_Tibble_Mid$negplog >= lower_value & GO_Tibble_Mid$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Mid, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,10))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Low
# Create a sample data frame
GO_Tibble_low <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 1
upper_percentile <- 33
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_low <- GO_Tibble_low[GO_Tibble_low$negplog >= lower_value & GO_Tibble_low$negplog <= upper_value, ]
GO_Tibble_low# A tibble: 24 × 10
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <fct> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:1901361 organic cy… 16/172 132/31… 1.61e-3 0.0437 0.0415 NPM1/… 16
2 GO:0016073 snRNA meta… 5/172 17/3193 1.56e-3 0.0429 0.0407 LARP7… 5
3 GO:0009891 positive r… 32/172 348/31… 1.35e-3 0.0383 0.0363 NPM1/… 32
4 GO:0019439 aromatic c… 16/172 130/31… 1.37e-3 0.0383 0.0363 NPM1/… 16
5 GO:0043484 regulation… 12/172 83/3193 1.37e-3 0.0383 0.0363 NCL/D… 12
6 GO:0010628 positive r… 24/172 232/31… 1.17e-3 0.0342 0.0324 NPM1/… 24
7 GO:0000470 maturation… 5/172 16/3193 1.15e-3 0.0340 0.0323 RPL7A… 5
8 GO:0044270 cellular n… 16/172 127/31… 1.06e-3 0.0318 0.0302 NPM1/… 16
9 GO:0032774 RNA biosyn… 40/172 459/31… 9.13e-4 0.0278 0.0264 H1-4/… 40
10 GO:0031328 positive r… 32/172 339/31… 8.60e-4 0.0270 0.0257 NPM1/… 32
# ℹ 14 more rows
# ℹ 1 more variable: negplog <dbl># Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_low, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,5))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = go_enrichment, showCategory = 5, categorySize = "pvalue" )
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)
edo <- pairwise_termsim(go_enrichment)
edo#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology BP
#...@keytype SYMBOL
#...@gene chr [1:183] "H1-4" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "DDX17" "RACK1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...74 enriched terms found
'data.frame': 74 obs. of 9 variables:
$ ID : chr "GO:0002181" "GO:0006412" "GO:0043043" "GO:0043604" ...
$ Description: chr "cytoplasmic translation" "translation" "peptide biosynthetic process" "amide biosynthetic process" ...
$ GeneRatio : chr "51/172" "70/172" "70/172" "71/172" ...
$ BgRatio : chr "104/3193" "317/3193" "324/3193" "374/3193" ...
$ pvalue : num 1.51e-39 1.39e-28 6.09e-28 1.18e-24 3.36e-23 ...
$ p.adjust : num 2.99e-36 1.38e-25 4.02e-25 5.86e-22 1.33e-20 ...
$ qvalue : num 2.84e-36 1.31e-25 3.81e-25 5.56e-22 1.26e-20 ...
$ geneID : chr "RPL4/RPS3/YBX1/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/YBX3/RPL30"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ "NPM1/NCL/RPL4/RACK1/RPS3/YBX1/RPL7A/RPS4X/RPS3A/DDX3X/PABPC1/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/PABPC4/"| __truncated__ ...
$ Count : int 51 70 70 71 70 71 38 61 71 29 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 p1 <- emapplot(edo, showCategory = 20, nCluster = 5)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2Warning: ggrepel: 11 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO CC Downregulated proteins
# 1.
# Do enrichment analysis of ENTREZ IDs from Padjusted value
# Perform GO enrichment analysis using the enrichGO function. We are using stringent cutoffs for Pvalue and q value in the testing! (this is good)
go_enrichment <- enrichGO(gene = DE_SYMBOL_Padj,
OrgDb = org.Hs.eg.db,
keyType = "SYMBOL",
universe = Background_SYMBOL,
ont = "CC",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05)
go_enrichment#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology CC
#...@keytype SYMBOL
#...@gene chr [1:183] "H1-4" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "DDX17" "RACK1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...27 enriched terms found
'data.frame': 27 obs. of 9 variables:
$ ID : chr "GO:0022626" "GO:1990904" "GO:0044391" "GO:0005840" ...
$ Description: chr "cytosolic ribosome" "ribonucleoprotein complex" "ribosomal subunit" "ribosome" ...
$ GeneRatio : chr "48/179" "80/179" "51/179" "52/179" ...
$ BgRatio : chr "78/3284" "367/3284" "141/3284" "155/3284" ...
$ pvalue : num 3.09e-43 2.62e-32 4.38e-31 7.66e-30 5.62e-22 ...
$ p.adjust : num 8.73e-41 3.71e-30 4.13e-29 5.42e-28 3.18e-20 ...
$ qvalue : num 7.83e-41 3.33e-30 3.71e-29 4.86e-28 2.85e-20 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "NPM1/NCL/RPL4/DDX17/RACK1/RPS3/YBX1/DDX5/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/SRRM2/RPS14/RPS18/RPS6/PT"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ ...
$ Count : int 48 80 51 52 25 23 25 26 44 16 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 # Go plot
goplot(x = go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# summary of the result that most people use
plot(barplot(go_enrichment, showCategory = 20))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- go_enrichment %>% as_tibble()
GO_Tibble# A tibble: 27 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:002… cytosolic … 48/179 78/3284 3.09e-43 8.73e-41 7.83e-41 RPL4/… 48
2 GO:199… ribonucleo… 80/179 367/32… 2.62e-32 3.71e-30 3.33e-30 NPM1/… 80
3 GO:004… ribosomal … 51/179 141/32… 4.38e-31 4.13e-29 3.71e-29 RPL4/… 51
4 GO:000… ribosome 52/179 155/32… 7.66e-30 5.42e-28 4.86e-28 RPL4/… 52
5 GO:002… cytosolic … 25/179 42/3284 5.62e-22 3.18e-20 2.85e-20 RPL4/… 25
6 GO:002… cytosolic … 23/179 36/3284 2.69e-21 1.27e-19 1.14e-19 RPS3/… 23
7 GO:001… small ribo… 25/179 58/3284 1.82e-17 7.36e-16 6.60e-16 RACK1… 25
8 GO:001… large ribo… 26/179 84/3284 5.40e-14 1.91e-12 1.71e-12 RPL4/… 26
9 GO:000… nucleolus 44/179 262/32… 1.89e-12 5.94e-11 5.32e-11 NPM1/… 44
10 GO:000… polysome 16/179 41/3284 9.76e-11 2.76e- 9 2.48e- 9 RPS3/… 16
# ℹ 17 more rows# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biologcal Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,100))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO_Tibble$negplog <- -log(GO_Tibble$p.adjust)
# Break up into high, medium and low siignfigance groups
# 1. High
# Create a sample data frame
GO_Tibble_Upper <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 67
upper_percentile <- 100
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Upper <- GO_Tibble_Upper[GO_Tibble_Upper$negplog >= lower_value & GO_Tibble_Upper$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Upper, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0, 70))Warning: Removed 1 rows containing missing values (`position_stack()`).
Removed 1 rows containing missing values (`position_stack()`).
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. Med
# Create a sample data frame
GO_Tibble_Mid <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 33
upper_percentile <- 67
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Mid <- GO_Tibble_Mid[GO_Tibble_Mid$negplog >= lower_value & GO_Tibble_Mid$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Mid, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,10))Warning: Removed 3 rows containing missing values (`position_stack()`).Warning: Removed 3 rows containing missing values (`position_stack()`).
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Low
# Create a sample data frame
GO_Tibble_low <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 1
upper_percentile <- 33
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_low <- GO_Tibble_low[GO_Tibble_low$negplog >= lower_value & GO_Tibble_low$negplog <= upper_value, ]
GO_Tibble_low# A tibble: 8 × 10
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <fct> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:0061695 transferas… 7/179 35/3284 2.33e-3 0.0253 0.0227 POLR2… 7
2 GO:0071013 catalytic … 10/179 57/3284 8.28e-4 0.00937 0.00840 DDX5/… 10
3 GO:0005694 chromosome 30/179 291/32… 3.57e-4 0.00422 0.00378 H1-4/… 30
4 GO:0000428 DNA-direct… 5/179 12/3284 2.64e-4 0.00324 0.00291 POLR2… 5
5 GO:0030880 RNA polyme… 5/179 12/3284 2.64e-4 0.00324 0.00291 POLR2… 5
6 GO:0055029 nuclear DN… 5/179 12/3284 2.64e-4 0.00324 0.00291 POLR2… 5
7 GO:0070161 anchoring … 35/179 348/32… 1.75e-4 0.00248 0.00222 NPM1/… 35
8 GO:0016607 nuclear sp… 19/179 136/32… 1.05e-4 0.00157 0.00140 DDX17… 19
# ℹ 1 more variable: negplog <dbl># Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_low, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,5))Warning: Removed 6 rows containing missing values (`position_stack()`).Warning: Removed 6 rows containing missing values (`position_stack()`).
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = go_enrichment, showCategory = 5, categorySize = "pvalue" )
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)
edo <- pairwise_termsim(go_enrichment)
edo#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology CC
#...@keytype SYMBOL
#...@gene chr [1:183] "H1-4" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "DDX17" "RACK1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...27 enriched terms found
'data.frame': 27 obs. of 9 variables:
$ ID : chr "GO:0022626" "GO:1990904" "GO:0044391" "GO:0005840" ...
$ Description: chr "cytosolic ribosome" "ribonucleoprotein complex" "ribosomal subunit" "ribosome" ...
$ GeneRatio : chr "48/179" "80/179" "51/179" "52/179" ...
$ BgRatio : chr "78/3284" "367/3284" "141/3284" "155/3284" ...
$ pvalue : num 3.09e-43 2.62e-32 4.38e-31 7.66e-30 5.62e-22 ...
$ p.adjust : num 8.73e-41 3.71e-30 4.13e-29 5.42e-28 3.18e-20 ...
$ qvalue : num 7.83e-41 3.33e-30 3.71e-29 4.86e-28 2.85e-20 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "NPM1/NCL/RPL4/DDX17/RACK1/RPS3/YBX1/DDX5/RPL7A/RPS4X/RPS3A/PABPC1/RPSA/RPL3/RPL8/RPS9/SRRM2/RPS14/RPS18/RPS6/PT"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ "RPL4/RACK1/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS"| __truncated__ ...
$ Count : int 48 80 51 52 25 23 25 26 44 16 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 p1 <- emapplot(edo, showCategory = 20, nCluster = 3)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
cowplot::plot_grid(p1, p2, p3, p4, ncol=2, labels=LETTERS[1:4])Warning: ggrepel: 4 unlabeled data points (too many overlaps). Consider
increasing max.overlapsWarning: ggrepel: 11 unlabeled data points (too many overlaps). Consider
increasing max.overlapsWarning: ggrepel: 20 unlabeled data points (too many overlaps). Consider increasing max.overlaps
ggrepel: 20 unlabeled data points (too many overlaps). Consider increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO Enrichment MF - Downregulated Genes
# 1.
# Do enrichment analysis of ENTREZ IDs from Padjusted value
# Perform GO enrichment analysis using the enrichGO function. We are using stringent cutoffs for Pvalue and q value in the testing! (this is good)
go_enrichment <- enrichGO(gene = DE_SYMBOL_Padj,
OrgDb = org.Hs.eg.db,
keyType = "SYMBOL",
universe = Background_SYMBOL,
ont = "MF",
pvalueCutoff = 0.05,
qvalueCutoff = 0.05)
go_enrichment#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology MF
#...@keytype SYMBOL
#...@gene chr [1:183] "H1-4" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "DDX17" "RACK1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...15 enriched terms found
'data.frame': 15 obs. of 9 variables:
$ ID : chr "GO:0003735" "GO:0005198" "GO:0003729" "GO:0003724" ...
$ Description: chr "structural constituent of ribosome" "structural molecule activity" "mRNA binding" "RNA helicase activity" ...
$ GeneRatio : chr "50/178" "54/178" "28/178" "12/178" ...
$ BgRatio : chr "129/3240" "303/3240" "155/3240" "33/3240" ...
$ pvalue : num 5.19e-32 2.06e-16 8.45e-09 6.75e-08 6.75e-08 ...
$ p.adjust : num 1.45e-29 2.89e-14 7.88e-07 3.78e-06 3.78e-06 ...
$ qvalue : num 1.31e-29 2.59e-14 7.08e-07 3.40e-06 3.40e-06 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "RPL4/KRT2/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/NUMA1/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10"| __truncated__ "NCL/RPS3/YBX1/DDX5/RPS3A/DDX3X/PABPC1/HNRNPA0/SRRM2/RPS14/PTBP2/PABPC4/SERBP1/G3BP1/YBX3/HDLBP/RPS5/RPL26/RPL24"| __truncated__ "DDX17/DDX5/DDX3X/G3BP1/DDX42/DDX21/DDX50/MTREX/DDX47/DDX18/DDX27/DDX41" ...
$ Count : int 50 54 28 12 12 22 36 25 13 11 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 # Go plot
goplot(x = go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# summary of the result that most people use
plot(barplot(go_enrichment, showCategory = 20))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- go_enrichment %>% as_tibble()
GO_Tibble# A tibble: 15 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:000… structural… 50/178 129/32… 5.19e-32 1.45e-29 1.31e-29 RPL4/… 50
2 GO:000… structural… 54/178 303/32… 2.06e-16 2.89e-14 2.59e-14 RPL4/… 54
3 GO:000… mRNA bindi… 28/178 155/32… 8.45e- 9 7.88e- 7 7.08e- 7 NCL/R… 28
4 GO:000… RNA helica… 12/178 33/3240 6.75e- 8 3.78e- 6 3.40e- 6 DDX17… 12
5 GO:000… ATP-depend… 12/178 33/3240 6.75e- 8 3.78e- 6 3.40e- 6 DDX17… 12
6 GO:014… catalytic … 22/178 124/32… 5.50e- 7 2.57e- 5 2.31e- 5 DDX17… 22
7 GO:000… DNA binding 36/178 298/32… 2.61e- 6 1.04e- 4 9.38e- 5 H1-4/… 36
8 GO:014… catalytic … 25/178 172/32… 4.29e- 6 1.50e- 4 1.35e- 4 DDX17… 25
9 GO:000… helicase a… 13/178 57/3240 7.82e- 6 2.43e- 4 2.19e- 4 DDX17… 13
10 GO:001… rRNA bindi… 11/178 42/3240 9.72e- 6 2.72e- 4 2.45e- 4 RPS3/… 11
11 GO:004… mRNA 5'-UT… 7/178 20/3240 5.66e- 5 1.44e- 3 1.29e- 3 NCL/R… 7
12 GO:000… poly(A) bi… 5/178 13/3240 4.25e- 4 9.91e- 3 8.90e- 3 DDX3X… 5
13 GO:000… mRNA 3'-UT… 9/178 47/3240 8.26e- 4 1.69e- 2 1.52e- 2 DDX5/… 9
14 GO:000… double-str… 16/178 122/32… 8.46e- 4 1.69e- 2 1.52e- 2 H1-4/… 16
15 GO:007… poly-purin… 5/178 16/3240 1.26e- 3 2.35e- 2 2.11e- 2 DDX3X… 5# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biologcal Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,75))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO_Tibble$negplog <- -log(GO_Tibble$p.adjust)
# Break up into high, medium and low siignfigance groups
# 1. High
# Create a sample data frame
GO_Tibble_Upper <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 67
upper_percentile <- 100
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Upper <- GO_Tibble_Upper[GO_Tibble_Upper$negplog >= lower_value & GO_Tibble_Upper$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Upper, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0, 70))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. Med
# Create a sample data frame
GO_Tibble_Mid <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 33
upper_percentile <- 67
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Mid <- GO_Tibble_Mid[GO_Tibble_Mid$negplog >= lower_value & GO_Tibble_Mid$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Mid, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,10))Warning: Removed 1 rows containing missing values (`position_stack()`).
Removed 1 rows containing missing values (`position_stack()`).
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Low
# Create a sample data frame
GO_Tibble_low <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 1
upper_percentile <- 33
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_low <- GO_Tibble_low[GO_Tibble_low$negplog >= lower_value & GO_Tibble_low$negplog <= upper_value, ]
GO_Tibble_low# A tibble: 4 × 10
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <fct> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 GO:0003730 mRNA 3'-UT… 9/178 47/3240 8.26e-4 0.0169 0.0152 DDX5/… 9
2 GO:0003690 double-str… 16/178 122/32… 8.46e-4 0.0169 0.0152 H1-4/… 16
3 GO:0008143 poly(A) bi… 5/178 13/3240 4.25e-4 0.00991 0.00890 DDX3X… 5
4 GO:0048027 mRNA 5'-UT… 7/178 20/3240 5.66e-5 0.00144 0.00129 NCL/R… 7
# ℹ 1 more variable: negplog <dbl># Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_low, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Biological Processes",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,5))Warning: Removed 1 rows containing missing values (`position_stack()`).
Removed 1 rows containing missing values (`position_stack()`).
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = go_enrichment, showCategory = 5, categorySize = "pvalue" )Warning: ggrepel: 3 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(go_enrichment, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)
edo <- pairwise_termsim(go_enrichment)
edo#
# over-representation test
#
#...@organism Homo sapiens
#...@ontology MF
#...@keytype SYMBOL
#...@gene chr [1:183] "H1-4" "NPM1" "NCL" "H1-2" "RPL4" "KRT2" "" "DDX17" "RACK1" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...15 enriched terms found
'data.frame': 15 obs. of 9 variables:
$ ID : chr "GO:0003735" "GO:0005198" "GO:0003729" "GO:0003724" ...
$ Description: chr "structural constituent of ribosome" "structural molecule activity" "mRNA binding" "RNA helicase activity" ...
$ GeneRatio : chr "50/178" "54/178" "28/178" "12/178" ...
$ BgRatio : chr "129/3240" "303/3240" "155/3240" "33/3240" ...
$ pvalue : num 5.19e-32 2.06e-16 8.45e-09 6.75e-08 6.75e-08 ...
$ p.adjust : num 1.45e-29 2.89e-14 7.88e-07 3.78e-06 3.78e-06 ...
$ qvalue : num 1.31e-29 2.59e-14 7.08e-07 3.40e-06 3.40e-06 ...
$ geneID : chr "RPL4/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10A/RPS15A/RP"| __truncated__ "RPL4/KRT2/RPS3/RPL7A/RPS4X/RPS3A/RPSA/RPL3/RPL8/RPS9/RPS14/NUMA1/RPS18/RPS6/RPS11/RPL27/RPS20/RPL17/RPL30/RPL10"| __truncated__ "NCL/RPS3/YBX1/DDX5/RPS3A/DDX3X/PABPC1/HNRNPA0/SRRM2/RPS14/PTBP2/PABPC4/SERBP1/G3BP1/YBX3/HDLBP/RPS5/RPL26/RPL24"| __truncated__ "DDX17/DDX5/DDX3X/G3BP1/DDX42/DDX21/DDX50/MTREX/DDX47/DDX18/DDX27/DDX41" ...
$ Count : int 50 54 28 12 12 22 36 25 13 11 ...
#...Citation
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu.
clusterProfiler 4.0: A universal enrichment tool for interpreting omics data.
The Innovation. 2021, 2(3):100141 p1 <- emapplot(edo, showCategory = 20, nCluster = 3)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
cowplot::plot_grid(p1, p2, p3, p4, ncol=2, labels=LETTERS[1:4])
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Enrich Pathway through reactome ENTREZ - DE_Pval
# Wrangle ENTREZ IDs for Pval
# 1. Read in the comprehensive DF that contains all sample info
Full_DF %>% head() Entrez.Gene.ID Ensembl.Gene.ID Gene.Symbol Accession
1 4625 ENSG00000092054 MYH7 P12883
2 4624 ENSG00000197616 MYH6 P13533
3 7273 ENSG00000155657 TTN Q8WZ42
4 70 ENSG00000159251 ACTC1 P68032
5 58 ENSG00000143632 ACTA1 P68133
6 60 ENSG00000075624 ACTB P60709
Abundance..F1..Sample..Dox..n.a Abundance..F3..Sample..Dox..n.a
1 5.25e+10 7.41e+10
2 1.00e+09 1.47e+09
3 1.39e+10 2.08e+10
4 3.92e+10 4.11e+10
5 1.72e+07 5.81e+07
6 4.02e+09 8.43e+08
Abundance..F5..Sample..Dox..Dox Abundance..F7..Sample..Dox..Dox
1 5.28e+10 6.82e+10
2 5.11e+09 4.25e+09
3 2.19e+10 2.49e+10
4 3.76e+10 3.54e+10
5 3.85e+07 5.07e+07
6 2.04e+09 1.62e+09
Abundance..F9..Sample..Dox..Dox Abundance..F2..Control..Veh..n.a
1 6.43e+10 4.33e+10
2 2.62e+09 1.50e+09
3 2.34e+10 1.29e+10
4 3.69e+10 3.54e+10
5 6.19e+07 1.64e+07
6 1.61e+09 4.16e+09
Abundance..F4..Control..Veh..n.a Abundance..F6..Control..Veh..Veh
1 7.41e+10 7.00e+10
2 1.17e+09 2.42e+09
3 2.25e+10 2.52e+10
4 2.96e+10 3.56e+10
5 3.44e+07 5.42e+07
6 6.45e+08 1.92e+09
Abundance..F8..Control..Veh..Veh Abundance..F10..Control..Veh..Veh
1 5.64e+10 5.26e+10
2 3.67e+09 3.27e+09
3 2.46e+10 2.21e+10
4 2.98e+10 2.91e+10
5 3.36e+07 4.05e+07
6 1.81e+09 1.56e+09# 2.
# Get set of DE proteins as per BH adjusted P-value
DE_ENTREZ_Padj <- toptable_Threshold_0.05 %>%
filter(adj.P.Val < 0.05) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% DE_ENTREZ_Padj)
# Subset the data frame
subset_Full_data <- Full_DF[rows, ]
# Here are the SYMBOL IDs for the DE proteins as per BH adj P value < 0.05
DE_ENTREZ_Padj <- subset_Full_data$Entrez.Gene.ID %>% unique() %>% na.omit()
DE_ENTREZ_Padj [1] "3008"
[2] "10381"
[3] "4869"
[4] "4691"
[5] "3006"
[6] "6124"
[7] "3849"
[8] ""
[9] "5052"
[10] "10521"
[11] "10399"
[12] "6188"
[13] "4904"
[14] "1655"
[15] "2969"
[16] "6130"
[17] "3308"
[18] "6191"
[19] "6189"
[20] "5501"
[21] "3276"
[22] "1654"
[23] "26986"
[24] "3921"
[25] "7158"
[26] "7086"
[27] "6122"
[28] "6132"
[29] "6203"
[30] "10949"
[31] "23524"
[32] "6208"
[33] "51602"
[34] "10493"
[35] "4926"
[36] "6222"
[37] "6194"
[38] "58155"
[39] "1108"
[40] "6624"
[41] "6205"
[42] "8761"
[43] "6155"
[44] "6224"
[45] "7407"
[46] "26135"
[47] "6139"
[48] "10146"
[49] "27034"
[50] "8531"
[51] "6156"
[52] "8106"
[53] "4736"
[54] "4702"
[55] "4076"
[56] "6210"
[57] "6133"
[58] "3069"
[59] "6193"
[60] "6154"
[61] "9584"
[62] "11325"
[63] "6217"
[64] "57646"
[65] "6206"
[66] "1808"
[67] "6138"
[68] "51295"
[69] "10552"
[70] "6147"
[71] "57175"
[72] "6152"
[73] "26156"
[74] "442721"
[75] "27063"
[76] "84324"
[77] "9578"
[78] "47"
[79] "6157"
[80] "10514"
[81] "9188"
[82] "6144"
[83] "23196"
[84] "6209"
[85] "7343"
[86] "57159"
[87] "9045"
[88] "8971"
[89] "6218"
[90] "6159"
[91] "988"
[92] "27333"
[93] "55234"
[94] "6229"
[95] "6165"
[96] "6223"
[97] "5356"
[98] "9100"
[99] "2043"
[100] "51300"
[101] "6164"
[102] "5411"
[103] "84656"
[104] "8731"
[105] "79009"
[106] "7057"
[107] "4698"
[108] "6230"
[109] "4924"
[110] "6231"
[111] "6181"
[112] "84676"
[113] "6161"
[114] "4809"
[115] "6166"
[116] "2653"
[117] "6160"
[118] "57669"
[119] "7779"
[120] "64778"
[121] "27109"
[122] "6173"
[123] "27332"
[124] "51574"
[125] "5531"
[126] "6168"
[127] "79718"
[128] "3550"
[129] "2697"
[130] "10573"
[131] "7436"
[132] "164312"
[133] "64710"
[134] "55327"
[135] "3992"
[136] "4154"
[137] "6204"
[138] "81631"
[139] "26097"
[140] "25873"
[141] "23394"
[142] "9482"
[143] "57538"
[144] "5431"
[145] "10159"
[146] "55226"
[147] "23517"
[148] "7916"
[149] "201931"
[150] "55920"
[151] "10072"
[152] "51755"
[153] "23066"
[154] "5937"
[155] "7412"
[156] "1523"
[157] "51202"
[158] "6235"
[159] "9444"
[160] "51637"
[161] "9415"
[162] "55506"
[163] "4179"
[164] "100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"
[165] "51106"
[166] "79577"
[167] "64949"
[168] "8886"
[169] "10447"
[170] "1909"
[171] "6234"
[172] "10227"
[173] "26354"
[174] "5430"
[175] "6510"
[176] "55661"
[177] "10458"
[178] "1901"
[179] "10598"
[180] "51010"
[181] "51503"
[182] "23016"
[183] "253943"
[184] "57819"
[185] "23378"
[186] "114990"
[187] "80349"
[188] "113251"
[189] "5394"
[190] "10285"
[191] "23677"
[192] "9126"
[193] "376132"
[194] "26058"
[195] "8110"
[196] "84270"
[197] "23094"
[198] "10298"
[199] "51428"
[200] "55366"
[201] "23481"
[202] "7162"
[203] "450831"
[204] "5434"
[205] "200916"
[206] "10664"
[207] "5511"
[208] "2289"
[209] "9902"
[210] "64745"
[211] "6482"
[212] "196528"
[213] "22981"
[214] "23013"
[215] "65264"
[216] "64425"
[217] "56112"
[218] "219402"
[219] "2531"
[220] "8900"
[221] "572"
[222] "219899"
[223] "6737"
[224] "79649" # Get background Symbol IDs
All_proteins_tested <- toptable_Threshold_0.05 %>%
filter(adj.P.Val < 1) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% All_proteins_tested)
# Subset the data frame
subset_back_data <- Full_DF[rows, ]
Background_ENTREZ <- subset_back_data$Entrez.Gene.ID %>% unique() %>% na.omit()
Background_ENTREZ [1] "4625"
[2] "4624"
[3] "7273"
[4] "70"
[5] "58"
[6] "60"
[7] "71"
[8] "4619"
[9] "4621"
[10] "4620"
[11] "506"
[12] "498"
[13] "4626"
[14] "8735"
[15] "4607"
[16] "3329"
[17] "2318"
[18] "6709"
[19] "6711"
[20] "79026"
[21] "7168"
[22] "2597"
[23] "291"
[24] "488"
[25] "165904"
[26] "88"
[27] "50"
[28] "293"
[29] "3418"
[30] "7139"
[31] "3309"
[32] "292"
[33] "7416"
[34] "3098"
[35] "4000"
[36] "8736"
[37] "87"
[38] "4191"
[39] "8470"
[40] "3030"
[41] "11155"
[42] "1756"
[43] "84033"
[44] "3312"
[45] "476"
[46] "2806"
[47] "3181"
[48] "5339"
[49] "7417"
[50] "871"
[51] "4967"
[52] "4259"
[53] "7184"
[54] "7169"
[55] "9131"
[56] ""
[57] "3848"
[58] "5034"
[59] "3313"
[60] "226"
[61] "5250"
[62] "302"
[63] "7414"
[64] "79933"
[65] "7431"
[66] "10529"
[67] "1213"
[68] "4634"
[69] "5591"
[70] "3032"
[71] "2271"
[72] "4633"
[73] "10128"
[74] "7170"
[75] "1915"
[76] "7385"
[77] "2316"
[78] "203068"
[79] "81"
[80] "1495"
[81] "1160"
[82] "5160"
[83] "6389"
[84] "10989"
[85] "10383"
[86] "7384"
[87] "1832"
[88] "821"
[89] "6840"
[90] "5315"
[91] "57142"
[92] "3192"
[93] "3875"
[94] "5162"
[95] "4635"
[96] "2923"
[97] "3856"
[98] "10935"
[99] "4627"
[100] "10763"
[101] "2274"
[102] "493"
[103] "3191"
[104] "4719"
[105] "6710"
[106] "309"
[107] "509"
[108] "478"
[109] "1431"
[110] "10970"
[111] "23530"
[112] "2023"
[113] "811"
[114] "7171"
[115] "1738"
[116] "7094"
[117] "3857"
[118] "3190"
[119] "3178"
[120] "2746"
[121] "3315"
[122] "5230"
[123] "7280"
[124] "3728"
[125] "3008"
[126] "288"
[127] "10611"
[128] "6546"
[129] "3858"
[130] "399687"
[131] "38"
[132] "477"
[133] "5318"
[134] "23193"
[135] "1778"
[136] "7415"
[137] "3895"
[138] "2108"
[139] "1666"
[140] "8291"
[141] "7846"
[142] "10449"
[143] "55699"
[144] "22989"
[145] "3419"
[146] "1727"
[147] "4670"
[148] "1917"
[149] "3326"
[150] "8048"
[151] "8209"
[152] "10105"
[153] "23499"
[154] "3320"
[155] "11331"
[156] "280717"
[157] "4976"
[158] "4628"
[159] "7419"
[160] "3609"
[161] "1660"
[162] "8604"
[163] "6233"
[164] "4008"
[165] "9124"
[166] "10155"
[167] "10381"
[168] "3028"
[169] "5479"
[170] "23136"
[171] "3688"
[172] "4869"
[173] "1327"
[174] "4720"
[175] "3336"
[176] "3009"
[177] "171024"
[178] "6184"
[179] "396058"
[180] "4001"
[181] "4841"
[182] "7277"
[183] "37"
[184] "58498"
[185] "4691"
[186] "3099"
[187] "3303; 3304"
[188] "3983"
[189] "3017"
[190] "1000"
[191] "8402"
[192] "9782"
[193] "9601"
[194] "1499"
[195] "3006"
[196] "2821"
[197] "6648"
[198] "7520"
[199] "5245"
[200] "287"
[201] "34"
[202] "51778"
[203] "91624"
[204] "1508"
[205] "2027"
[206] "427"
[207] "1743"
[208] "1500"
[209] "2109"
[210] "2058"
[211] "10130"
[212] "3685"
[213] "7135"
[214] "1509"
[215] "1737"
[216] "8349"
[217] "3007"
[218] "4190"
[219] "51706"
[220] "8570"
[221] "6421"
[222] "83660"
[223] "8803"
[224] "3033"
[225] "5214"
[226] "6238"
[227] "220988"
[228] "6262"
[229] "9868"
[230] "1891"
[231] "4059"
[232] "217"
[233] "7430"
[234] "2744"
[235] "23788"
[236] "2317"
[237] "10939"
[238] "10525"
[239] "4723"
[240] "445815"
[241] "150572"
[242] "7037"
[243] "4684"
[244] "1674"
[245] "5834"
[246] "6124"
[247] "27044"
[248] "84617"
[249] "9361"
[250] "1809"
[251] "2547"
[252] "3295"
[253] "8659"
[254] "8411"
[255] "10236"
[256] "3849"
[257] "7386"
[258] "94081"
[259] "5223"
[260] "1938"
[261] "6185"
[262] "10131"
[263] "4478"
[264] "10549"
[265] "11149"
[266] "23451"
[267] "6472"
[268] "10642"
[269] "10165"
[270] "142"
[271] "5052"
[272] "146862"
[273] "4704"
[274] "539"
[275] "3420"
[276] "10521"
[277] "5019"
[278] "4329"
[279] "3912"
[280] "23022"
[281] "1264"
[282] "10399"
[283] "3184"
[284] "1537"
[285] "3880"
[286] "4705"
[287] "163"
[288] "1937"
[289] "7919"
[290] "3915"
[291] "30"
[292] "6647"
[293] "3270"
[294] "27316"
[295] "3868"
[296] "3861"
[297] "4240"
[298] "3939"
[299] "501"
[300] "2631"
[301] "27339"
[302] "4722"
[303] "481"
[304] "56886"
[305] "4134"
[306] "3187"
[307] "6188"
[308] "23363"
[309] "682"
[310] "4637"
[311] "4660"
[312] "3482"
[313] "1892"
[314] "8880"
[315] "490"
[316] "5500"
[317] "10531"
[318] "57506"
[319] "1384"
[320] "9948"
[321] "3945"
[322] "160"
[323] "84823"
[324] "3188"
[325] "6426"
[326] "6428"
[327] "55210"
[328] "118"
[329] "23597"
[330] "54927"
[331] "25824"
[332] "3608"
[333] "5708"
[334] "10492"
[335] "641371"
[336] "2771"
[337] "1397"
[338] "10965"
[339] "749887"
[340] "23180"
[341] "230"
[342] "3954"
[343] "18"
[344] "2805"
[345] "6640"
[346] "4659"
[347] "5239"
[348] "1994"
[349] "64087"
[350] "7001"
[351] "10455"
[352] "8802"
[353] "224"
[354] "7317"
[355] "80221"
[356] "54504"
[357] "29119"
[358] "3853"
[359] "5859"
[360] "4904"
[361] "4641"
[362] "10469"
[363] "1655"
[364] "7871"
[365] "5161"
[366] "6566"
[367] "7082"
[368] "8661"
[369] "5962"
[370] "10643"
[371] "5589"
[372] "3305"
[373] "3421"
[374] "7112"
[375] "10576"
[376] "2969"
[377] "1376"
[378] "1314"
[379] "23065"
[380] "1642"
[381] "9218"
[382] "3852"
[383] "10452"
[384] "5499"
[385] "1158"
[386] "4200"
[387] "5095"
[388] "23203"
[389] "36"
[390] "57805"
[391] "1632"
[392] "64091"
[393] "28976"
[394] "50808"
[395] "387"
[396] "1653"
[397] "25813"
[398] "7360"
[399] "9217"
[400] "7402"
[401] "7111"
[402] "8087"
[403] "1981"
[404] "84263"
[405] "2110"
[406] "10157"
[407] "10211"
[408] "204"
[409] "6130"
[410] "2180"
[411] "80017"
[412] "3998"
[413] "3308"
[414] "3712"
[415] "10694"
[416] "2232"
[417] "5862"
[418] "10147"
[419] "8508"
[420] "7203"
[421] "2782"
[422] "6128"
[423] "51056"
[424] "51520"
[425] "3837"
[426] "3679"
[427] "84896"
[428] "4513"
[429] "813"
[430] "6191"
[431] "10160"
[432] "79784"
[433] "2017"
[434] "56922"
[435] "221092"
[436] "92140"
[437] "144100"
[438] "800"
[439] "3842"
[440] "6189"
[441] "373156"
[442] "2319"
[443] "7175"
[444] "1429"
[445] "6390"
[446] "23078"
[447] "6520"
[448] "8338"
[449] "7155"
[450] "10291"
[451] "4043"
[452] "55157"
[453] "9927"
[454] "5501"
[455] "84675"
[456] "1464"
[457] "1829"
[458] "444"
[459] "8050"
[460] "10992"
[461] "587"
[462] "284119"
[463] "84940"
[464] "1410"
[465] "3276"
[466] "60681"
[467] "494115"
[468] "989"
[469] "4905"
[470] "6129"
[471] "5163"
[472] "3054"
[473] "8801"
[474] "23450"
[475] "515"
[476] "2720"
[477] "23654"
[478] "2521"
[479] "1654"
[480] "5236"
[481] "10960"
[482] "11112"
[483] "285025"
[484] "55750"
[485] "1072"
[486] "817"
[487] "10575"
[488] "4131"
[489] "3913"
[490] "81567"
[491] "6125"
[492] "84700"
[493] "3146"
[494] "5576"
[495] "2783"
[496] "5861"
[497] "8663"
[498] "35"
[499] "10972"
[500] "56945"
[501] "7531"
[502] "26986"
[503] "3921"
[504] "10651"
[505] "9512"
[506] "7818"
[507] "89941"
[508] "55967"
[509] "5033"
[510] "4162"
[511] "4047"
[512] "7158"
[513] "85476"
[514] "283820"
[515] "9230"
[516] "3872"
[517] "10857"
[518] "4831; 654364"
[519] "421"
[520] "1615"
[521] "51449"
[522] "5682"
[523] "55037"
[524] "593"
[525] "2548"
[526] "5837"
[527] "1374"
[528] "10890"
[529] "1200"
[530] "7086"
[531] "23420"
[532] "223"
[533] "27020"
[534] "161"
[535] "10644"
[536] "3855"
[537] "23646"
[538] "6122"
[539] "2026"
[540] "51493"
[541] "7841"
[542] "57136"
[543] "80142"
[544] "57158"
[545] "9987"
[546] "1627"
[547] "1605"
[548] "23603"
[549] "11100"
[550] "2997"
[551] "2235"
[552] "10484"
[553] "6132"
[554] "50809"
[555] "10528"
[556] "51097"
[557] "54940"
[558] "5350"
[559] "2091"
[560] "4012"
[561] "8148"
[562] "6203"
[563] "2817"
[564] "10486"
[565] "23020"
[566] "8540"
[567] "51552"
[568] "27068"
[569] "51253"
[570] "6741"
[571] "3339"
[572] "3376"
[573] "92609"
[574] "79135"
[575] "6202"
[576] "1173"
[577] "10574"
[578] "10949"
[579] "5518"
[580] "87178"
[581] "2820"
[582] "11338"
[583] "57326"
[584] "30968"
[585] "5573"
[586] "22948"
[587] "51593"
[588] "205"
[589] "10961"
[590] "377"
[591] "23524"
[592] "5717"
[593] "1629"
[594] "5707"
[595] "55379"
[596] "10096"
[597] "11021"
[598] "57498"
[599] "5917"
[600] "3927"
[601] "100526737; 10432"
[602] "10290"
[603] "9377"
[604] "6625"
[605] "6201"
[606] "6137"
[607] "5037"
[608] "55847"
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[1977] "5050"
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[1981] "64834"
[1982] "122961"
[1983] "10670"
[1984] "64951"
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[1986] "10980"
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[1989] "57727"
[1990] "8825"
[1991] "154807"
[1992] "2710"
[1993] "80331"
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[1995] "2697"
[1996] "54953"
[1997] "54534"
[1998] "29789"
[1999] "387522; 7335"
[2000] "1460"
[2001] "2519"
[2002] "3839"
[2003] "51218"
[2004] "10713"
[2005] "57552"
[2006] "984"
[2007] "5371"
[2008] "10573"
[2009] "79572"
[2010] "7436"
[2011] "6733"
[2012] "79714"
[2013] "64924"
[2014] "348995"
[2015] "28969"
[2016] "10434"
[2017] "345778"
[2018] "81887"
[2019] "1284"
[2020] "56255"
[2021] "4920"
[2022] "8451"
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[3324] "2186" # Fusion proteins in ENTREZ ids. Therefore, need to split them up
# vector to split
my_vector_test <- DE_ENTREZ_Padj
# Split the elements of the vector on semicolons
split_vector <- strsplit(my_vector_test, split = ";")
# Unlist the split vector
new_vector_ENTREZ <- unlist(split_vector)
# Do the same for background
back_vector_test <- Background_ENTREZ
# Split the elements of the vector on semicolons
split_vector <- strsplit(back_vector_test, split = ";")
# Unlist the split vector
back_new_vector_ENTREZ <- unlist(split_vector)
EnrichPathobj <- ReactomePA::enrichPathway(
new_vector_ENTREZ,
organism = "human",
pvalueCutoff = 0.05,
pAdjustMethod = "BH",
qvalueCutoff = 0.05,
universe = back_new_vector_ENTREZ,
minGSSize = 2,
maxGSSize = 500,
readable = FALSE
)
EnrichPathobj#
# over-representation test
#
#...@organism human
#...@ontology Reactome
#...@keytype ENTREZID
#...@gene chr [1:252] "3008" "10381" "4869" "4691" "3006" "6124" "3849" "5052" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...48 enriched terms found
'data.frame': 48 obs. of 9 variables:
$ ID : chr "R-HSA-8868773" "R-HSA-6791226" "R-HSA-72312" "R-HSA-2408557" ...
$ Description: chr "rRNA processing in the nucleus and cytosol" "Major pathway of rRNA processing in the nucleolus and cytosol" "rRNA processing" "Selenocysteine synthesis" ...
$ GeneRatio : chr "62/171" "61/171" "63/171" "50/171" ...
$ BgRatio : chr "109/2484" "106/2484" "118/2484" "75/2484" ...
$ pvalue : num 1.21e-47 3.06e-47 4.04e-46 6.60e-43 1.83e-42 ...
$ p.adjust : num 7.07e-45 8.93e-45 7.86e-44 9.62e-41 1.78e-40 ...
$ qvalue : num 6.26e-45 7.90e-45 6.95e-44 8.51e-41 1.58e-40 ...
$ geneID : chr "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/51602/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/"| __truncated__ "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/51602/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/"| __truncated__ "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/51602/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/"| __truncated__ "6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/6193/6154/6"| __truncated__ ...
$ Count : int 62 61 63 50 50 50 51 50 50 50 ...
#...Citation
Guangchuang Yu, Qing-Yu He. ReactomePA: an R/Bioconductor package for
reactome pathway analysis and visualization. Molecular BioSystems
2016, 12(2):477-479 # summary of the result that most people use
plot(barplot(EnrichPathobj, showCategory = 15 ))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- EnrichPathobj %>% as_tibble()
GO_Tibble# A tibble: 48 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 R-HSA-… rRNA proce… 62/171 109/24… 1.21e-47 7.07e-45 6.26e-45 4691/… 62
2 R-HSA-… Major path… 61/171 106/24… 3.06e-47 8.93e-45 7.90e-45 4691/… 61
3 R-HSA-… rRNA proce… 63/171 118/24… 4.04e-46 7.86e-44 6.95e-44 4691/… 63
4 R-HSA-… Selenocyst… 50/171 75/2484 6.60e-43 9.62e-41 8.51e-41 6124/… 50
5 R-HSA-… Peptide ch… 50/171 76/2484 1.83e-42 1.78e-40 1.58e-40 6124/… 50
6 R-HSA-… Viral mRNA… 50/171 76/2484 1.83e-42 1.78e-40 1.58e-40 6124/… 50
7 R-HSA-… Nonsense M… 51/171 80/2484 2.69e-42 2.24e-40 1.98e-40 6124/… 51
8 R-HSA-… Eukaryotic… 50/171 77/2484 4.97e-42 3.22e-40 2.85e-40 6124/… 50
9 R-HSA-… Response o… 50/171 77/2484 4.97e-42 3.22e-40 2.85e-40 6124/… 50
10 R-HSA-… Eukaryotic… 50/171 80/2484 8.65e-41 5.04e-39 4.46e-39 6124/… 50
# ℹ 38 more rowswrite_csv(x = GO_Tibble, file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Data_Frames/Important_DF_Final/Reactome_Tibble.csv")
# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,105))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GO_Tibble$negplog <- -log(GO_Tibble$p.adjust)
# Break up into high, medium and low siignfigance groups
# 1. High
# Create a sample data frame
GO_Tibble_Upper <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 67
upper_percentile <- 100
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Upper <- GO_Tibble_Upper[GO_Tibble_Upper$negplog >= lower_value & GO_Tibble_Upper$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Upper, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,130))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. Med
# Create a sample data frame
GO_Tibble_Mid <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 33
upper_percentile <- 67
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_Mid <- GO_Tibble_Mid[GO_Tibble_Mid$negplog >= lower_value & GO_Tibble_Mid$negplog <= upper_value, ]
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_Mid, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,100))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Low
# Create a sample data frame
GO_Tibble_low <- GO_Tibble
# Define the lower and upper percentile values
lower_percentile <- 1
upper_percentile <- 33
# Calculate the percentile values for the 'Value' column
lower_value <- quantile(GO_Tibble$negplog, probs = lower_percentile / 100)
upper_value <- quantile(GO_Tibble$negplog, probs = upper_percentile / 100)
# Subset the data frame based on the percentile range
GO_Tibble_low <- GO_Tibble_low[GO_Tibble_low$negplog >= lower_value & GO_Tibble_low$negplog <= upper_value, ]
GO_Tibble_low# A tibble: 16 × 10
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <fct> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 R-HSA-… FGFR2 muta… 3/171 4/2484 1.22e- 3 1.51e- 2 1.34e- 2 5431/… 3
2 R-HSA-… Signaling … 3/171 4/2484 1.22e- 3 1.51e- 2 1.34e- 2 5431/… 3
3 R-HSA-… mRNA Cappi… 4/171 8/2484 1.22e- 3 1.51e- 2 1.34e- 2 8731/… 4
4 R-HSA-… RNA Pol II… 4/171 7/2484 6.44e- 4 8.54e- 3 7.55e- 3 8731/… 4
5 R-HSA-… RNA Pol II… 4/171 7/2484 6.44e- 4 8.54e- 3 7.55e- 3 8731/… 4
6 R-HSA-… rRNA modif… 7/171 17/2484 7.00e- 5 9.72e- 4 8.60e- 4 6203/… 7
7 R-HSA-… SARS-CoV I… 31/171 171/24… 2.02e- 7 2.87e- 6 2.54e- 6 6188/… 31
8 R-HSA-… SARS-CoV-2… 29/171 134/24… 8.41e- 9 1.23e- 7 1.08e- 7 6188/… 29
9 R-HSA-… SARS-CoV-2… 26/171 102/24… 1.32e- 9 1.97e- 8 1.74e- 8 6188/… 26
10 R-HSA-… Ribosomal … 23/171 56/2484 1.94e-13 2.98e-12 2.64e-12 6188/… 23
11 R-HSA-… Translatio… 24/171 56/2484 1.72e-14 2.71e-13 2.40e-13 6188/… 24
12 R-HSA-… Activation… 24/171 56/2484 1.72e-14 2.71e-13 2.40e-13 6188/… 24
13 R-HSA-… Formation … 23/171 49/2484 5.44e-15 9.06e-14 8.01e-14 6188/… 23
14 R-HSA-… Infectious… 68/171 379/24… 4.05e-16 6.94e-15 6.14e-15 10381… 68
15 R-HSA-… Cellular r… 64/171 337/24… 2.34e-16 4.13e-15 3.65e-15 3008/… 64
16 R-HSA-… Cellular r… 64/171 337/24… 2.34e-16 4.13e-15 3.65e-15 3008/… 64
# ℹ 1 more variable: negplog <dbl># Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble_low, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,35))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#* the input for these plots will be one of the following variables
#* that we obtained in previous sections of the code, such as 1. go_enrichment,
#* 2. EnrichPathobj, or 3. enrichdiseaseobj.
#*
cnetplot(x = EnrichPathobj, showCategory = 5, categorySize = "pvalue" )Warning: ggrepel: 1 unlabeled data points (too many overlaps). Consider
increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# heatplot to see gene overlaps
heatplot(EnrichPathobj, showCategory = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Enrichmap by emapplot
library(enrichplot)
edo <- pairwise_termsim(EnrichPathobj)
edo#
# over-representation test
#
#...@organism human
#...@ontology Reactome
#...@keytype ENTREZID
#...@gene chr [1:252] "3008" "10381" "4869" "4691" "3006" "6124" "3849" "5052" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...48 enriched terms found
'data.frame': 48 obs. of 9 variables:
$ ID : chr "R-HSA-8868773" "R-HSA-6791226" "R-HSA-72312" "R-HSA-2408557" ...
$ Description: chr "rRNA processing in the nucleus and cytosol" "Major pathway of rRNA processing in the nucleolus and cytosol" "rRNA processing" "Selenocysteine synthesis" ...
$ GeneRatio : chr "62/171" "61/171" "63/171" "50/171" ...
$ BgRatio : chr "109/2484" "106/2484" "118/2484" "75/2484" ...
$ pvalue : num 1.21e-47 3.06e-47 4.04e-46 6.60e-43 1.83e-42 ...
$ p.adjust : num 7.07e-45 8.93e-45 7.86e-44 9.62e-41 1.78e-40 ...
$ qvalue : num 6.26e-45 7.90e-45 6.95e-44 8.51e-41 1.58e-40 ...
$ geneID : chr "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/51602/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/"| __truncated__ "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/51602/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/"| __truncated__ "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/51602/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/"| __truncated__ "6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/6193/6154/6"| __truncated__ ...
$ Count : int 62 61 63 50 50 50 51 50 50 50 ...
#...Citation
Guangchuang Yu, Qing-Yu He. ReactomePA: an R/Bioconductor package for
reactome pathway analysis and visualization. Molecular BioSystems
2016, 12(2):477-479 p1 <- emapplot(edo, showCategory = 15, nCluster = 3)
p1
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p2 <- emapplot(edo, cex_category=1.5)
p2
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p3 <- emapplot(edo, layout="kk")
p3
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
p4 <- emapplot(edo, cex_category=1.5,layout="kk")
p4
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
cowplot::plot_grid(p1, p2, p3, p4, ncol=2, labels=LETTERS[1:4])Warning: ggrepel: 25 unlabeled data points (too many overlaps). Consider
increasing max.overlapsWarning: ggrepel: 18 unlabeled data points (too many overlaps). Consider increasing max.overlaps
ggrepel: 18 unlabeled data points (too many overlaps). Consider increasing max.overlaps
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Enrich Pathway through reactome downregulated DE ENTREZ - DE_Pval
# Wrangle ENTREZ IDs for Pval
# 1. Read in the comprehensive DF that contains all sample info
Full_DF %>% head() Entrez.Gene.ID Ensembl.Gene.ID Gene.Symbol Accession
1 4625 ENSG00000092054 MYH7 P12883
2 4624 ENSG00000197616 MYH6 P13533
3 7273 ENSG00000155657 TTN Q8WZ42
4 70 ENSG00000159251 ACTC1 P68032
5 58 ENSG00000143632 ACTA1 P68133
6 60 ENSG00000075624 ACTB P60709
Abundance..F1..Sample..Dox..n.a Abundance..F3..Sample..Dox..n.a
1 5.25e+10 7.41e+10
2 1.00e+09 1.47e+09
3 1.39e+10 2.08e+10
4 3.92e+10 4.11e+10
5 1.72e+07 5.81e+07
6 4.02e+09 8.43e+08
Abundance..F5..Sample..Dox..Dox Abundance..F7..Sample..Dox..Dox
1 5.28e+10 6.82e+10
2 5.11e+09 4.25e+09
3 2.19e+10 2.49e+10
4 3.76e+10 3.54e+10
5 3.85e+07 5.07e+07
6 2.04e+09 1.62e+09
Abundance..F9..Sample..Dox..Dox Abundance..F2..Control..Veh..n.a
1 6.43e+10 4.33e+10
2 2.62e+09 1.50e+09
3 2.34e+10 1.29e+10
4 3.69e+10 3.54e+10
5 6.19e+07 1.64e+07
6 1.61e+09 4.16e+09
Abundance..F4..Control..Veh..n.a Abundance..F6..Control..Veh..Veh
1 7.41e+10 7.00e+10
2 1.17e+09 2.42e+09
3 2.25e+10 2.52e+10
4 2.96e+10 3.56e+10
5 3.44e+07 5.42e+07
6 6.45e+08 1.92e+09
Abundance..F8..Control..Veh..Veh Abundance..F10..Control..Veh..Veh
1 5.64e+10 5.26e+10
2 3.67e+09 3.27e+09
3 2.46e+10 2.21e+10
4 2.98e+10 2.91e+10
5 3.36e+07 4.05e+07
6 1.81e+09 1.56e+09# 2.
# Get set of DE proteins as per BH adjusted P-value
DE_ENTREZ_Padj <- toptable_Threshold_0.05 %>%
filter((logFC < 0 )&(adj.P.Val < 0.05)) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% DE_ENTREZ_Padj)
# Subset the data frame
subset_Full_data <- Full_DF[rows, ]
# Here are the SYMBOL IDs for the DE proteins as per BH adj P value < 0.05
DE_ENTREZ_Padj <- subset_Full_data$Entrez.Gene.ID %>% unique() %>% na.omit()
DE_ENTREZ_Padj [1] "3008"
[2] "4869"
[3] "4691"
[4] "3006"
[5] "6124"
[6] "3849"
[7] ""
[8] "10521"
[9] "10399"
[10] "6188"
[11] "4904"
[12] "1655"
[13] "2969"
[14] "6130"
[15] "6191"
[16] "6189"
[17] "5501"
[18] "1654"
[19] "26986"
[20] "3921"
[21] "7158"
[22] "6122"
[23] "6132"
[24] "6203"
[25] "10949"
[26] "23524"
[27] "6208"
[28] "4926"
[29] "6222"
[30] "6194"
[31] "58155"
[32] "1108"
[33] "6205"
[34] "8761"
[35] "6155"
[36] "6224"
[37] "26135"
[38] "6139"
[39] "10146"
[40] "8531"
[41] "6156"
[42] "8106"
[43] "4736"
[44] "4702"
[45] "4076"
[46] "6210"
[47] "6133"
[48] "3069"
[49] "6193"
[50] "6154"
[51] "9584"
[52] "11325"
[53] "6217"
[54] "57646"
[55] "6206"
[56] "6138"
[57] "6147"
[58] "6152"
[59] "26156"
[60] "442721"
[61] "27063"
[62] "84324"
[63] "9578"
[64] "6157"
[65] "10514"
[66] "9188"
[67] "6144"
[68] "23196"
[69] "6209"
[70] "57159"
[71] "9045"
[72] "8971"
[73] "6218"
[74] "6159"
[75] "988"
[76] "27333"
[77] "55234"
[78] "6229"
[79] "6165"
[80] "6223"
[81] "5356"
[82] "9100"
[83] "51300"
[84] "6164"
[85] "5411"
[86] "8731"
[87] "79009"
[88] "7057"
[89] "4698"
[90] "6230"
[91] "4924"
[92] "6231"
[93] "6181"
[94] "84676"
[95] "6161"
[96] "6166"
[97] "6160"
[98] "64778"
[99] "27109"
[100] "6173"
[101] "27332"
[102] "51574"
[103] "5531"
[104] "6168"
[105] "79718"
[106] "3550"
[107] "2697"
[108] "10573"
[109] "7436"
[110] "164312"
[111] "55327"
[112] "3992"
[113] "4154"
[114] "6204"
[115] "26097"
[116] "25873"
[117] "23394"
[118] "9482"
[119] "57538"
[120] "5431"
[121] "55226"
[122] "23517"
[123] "7916"
[124] "201931"
[125] "51755"
[126] "23066"
[127] "5937"
[128] "7412"
[129] "1523"
[130] "51202"
[131] "6235"
[132] "9444"
[133] "51637"
[134] "9415"
[135] "100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"
[136] "51106"
[137] "79577"
[138] "64949"
[139] "8886"
[140] "10447"
[141] "1909"
[142] "6234"
[143] "26354"
[144] "5430"
[145] "55661"
[146] "1901"
[147] "51010"
[148] "51503"
[149] "23016"
[150] "253943"
[151] "57819"
[152] "23378"
[153] "80349"
[154] "113251"
[155] "5394"
[156] "10285"
[157] "23677"
[158] "9126"
[159] "376132"
[160] "26058"
[161] "8110"
[162] "84270"
[163] "10298"
[164] "51428"
[165] "55366"
[166] "23481"
[167] "450831"
[168] "5434"
[169] "200916"
[170] "10664"
[171] "5511"
[172] "9902"
[173] "64745"
[174] "6482"
[175] "196528"
[176] "64425"
[177] "56112"
[178] "219402"
[179] "8900"
[180] "572"
[181] "219899"
[182] "6737"
[183] "79649" # Get background Symbol IDs
All_proteins_tested <- toptable_Threshold_0.05 %>%
filter(adj.P.Val < 1) %>% rownames()
# Get SYMBOL ID for the proteins in DE_proteins_Padj
# Find the rows where 'var' is in 'values'
rows <- which(Full_DF$Accession %in% All_proteins_tested)
# Subset the data frame
subset_back_data <- Full_DF[rows, ]
Background_ENTREZ <- subset_back_data$Entrez.Gene.ID %>% unique() %>% na.omit()
Background_ENTREZ [1] "4625"
[2] "4624"
[3] "7273"
[4] "70"
[5] "58"
[6] "60"
[7] "71"
[8] "4619"
[9] "4621"
[10] "4620"
[11] "506"
[12] "498"
[13] "4626"
[14] "8735"
[15] "4607"
[16] "3329"
[17] "2318"
[18] "6709"
[19] "6711"
[20] "79026"
[21] "7168"
[22] "2597"
[23] "291"
[24] "488"
[25] "165904"
[26] "88"
[27] "50"
[28] "293"
[29] "3418"
[30] "7139"
[31] "3309"
[32] "292"
[33] "7416"
[34] "3098"
[35] "4000"
[36] "8736"
[37] "87"
[38] "4191"
[39] "8470"
[40] "3030"
[41] "11155"
[42] "1756"
[43] "84033"
[44] "3312"
[45] "476"
[46] "2806"
[47] "3181"
[48] "5339"
[49] "7417"
[50] "871"
[51] "4967"
[52] "4259"
[53] "7184"
[54] "7169"
[55] "9131"
[56] ""
[57] "3848"
[58] "5034"
[59] "3313"
[60] "226"
[61] "5250"
[62] "302"
[63] "7414"
[64] "79933"
[65] "7431"
[66] "10529"
[67] "1213"
[68] "4634"
[69] "5591"
[70] "3032"
[71] "2271"
[72] "4633"
[73] "10128"
[74] "7170"
[75] "1915"
[76] "7385"
[77] "2316"
[78] "203068"
[79] "81"
[80] "1495"
[81] "1160"
[82] "5160"
[83] "6389"
[84] "10989"
[85] "10383"
[86] "7384"
[87] "1832"
[88] "821"
[89] "6840"
[90] "5315"
[91] "57142"
[92] "3192"
[93] "3875"
[94] "5162"
[95] "4635"
[96] "2923"
[97] "3856"
[98] "10935"
[99] "4627"
[100] "10763"
[101] "2274"
[102] "493"
[103] "3191"
[104] "4719"
[105] "6710"
[106] "309"
[107] "509"
[108] "478"
[109] "1431"
[110] "10970"
[111] "23530"
[112] "2023"
[113] "811"
[114] "7171"
[115] "1738"
[116] "7094"
[117] "3857"
[118] "3190"
[119] "3178"
[120] "2746"
[121] "3315"
[122] "5230"
[123] "7280"
[124] "3728"
[125] "3008"
[126] "288"
[127] "10611"
[128] "6546"
[129] "3858"
[130] "399687"
[131] "38"
[132] "477"
[133] "5318"
[134] "23193"
[135] "1778"
[136] "7415"
[137] "3895"
[138] "2108"
[139] "1666"
[140] "8291"
[141] "7846"
[142] "10449"
[143] "55699"
[144] "22989"
[145] "3419"
[146] "1727"
[147] "4670"
[148] "1917"
[149] "3326"
[150] "8048"
[151] "8209"
[152] "10105"
[153] "23499"
[154] "3320"
[155] "11331"
[156] "280717"
[157] "4976"
[158] "4628"
[159] "7419"
[160] "3609"
[161] "1660"
[162] "8604"
[163] "6233"
[164] "4008"
[165] "9124"
[166] "10155"
[167] "10381"
[168] "3028"
[169] "5479"
[170] "23136"
[171] "3688"
[172] "4869"
[173] "1327"
[174] "4720"
[175] "3336"
[176] "3009"
[177] "171024"
[178] "6184"
[179] "396058"
[180] "4001"
[181] "4841"
[182] "7277"
[183] "37"
[184] "58498"
[185] "4691"
[186] "3099"
[187] "3303; 3304"
[188] "3983"
[189] "3017"
[190] "1000"
[191] "8402"
[192] "9782"
[193] "9601"
[194] "1499"
[195] "3006"
[196] "2821"
[197] "6648"
[198] "7520"
[199] "5245"
[200] "287"
[201] "34"
[202] "51778"
[203] "91624"
[204] "1508"
[205] "2027"
[206] "427"
[207] "1743"
[208] "1500"
[209] "2109"
[210] "2058"
[211] "10130"
[212] "3685"
[213] "7135"
[214] "1509"
[215] "1737"
[216] "8349"
[217] "3007"
[218] "4190"
[219] "51706"
[220] "8570"
[221] "6421"
[222] "83660"
[223] "8803"
[224] "3033"
[225] "5214"
[226] "6238"
[227] "220988"
[228] "6262"
[229] "9868"
[230] "1891"
[231] "4059"
[232] "217"
[233] "7430"
[234] "2744"
[235] "23788"
[236] "2317"
[237] "10939"
[238] "10525"
[239] "4723"
[240] "445815"
[241] "150572"
[242] "7037"
[243] "4684"
[244] "1674"
[245] "5834"
[246] "6124"
[247] "27044"
[248] "84617"
[249] "9361"
[250] "1809"
[251] "2547"
[252] "3295"
[253] "8659"
[254] "8411"
[255] "10236"
[256] "3849"
[257] "7386"
[258] "94081"
[259] "5223"
[260] "1938"
[261] "6185"
[262] "10131"
[263] "4478"
[264] "10549"
[265] "11149"
[266] "23451"
[267] "6472"
[268] "10642"
[269] "10165"
[270] "142"
[271] "5052"
[272] "146862"
[273] "4704"
[274] "539"
[275] "3420"
[276] "10521"
[277] "5019"
[278] "4329"
[279] "3912"
[280] "23022"
[281] "1264"
[282] "10399"
[283] "3184"
[284] "1537"
[285] "3880"
[286] "4705"
[287] "163"
[288] "1937"
[289] "7919"
[290] "3915"
[291] "30"
[292] "6647"
[293] "3270"
[294] "27316"
[295] "3868"
[296] "3861"
[297] "4240"
[298] "3939"
[299] "501"
[300] "2631"
[301] "27339"
[302] "4722"
[303] "481"
[304] "56886"
[305] "4134"
[306] "3187"
[307] "6188"
[308] "23363"
[309] "682"
[310] "4637"
[311] "4660"
[312] "3482"
[313] "1892"
[314] "8880"
[315] "490"
[316] "5500"
[317] "10531"
[318] "57506"
[319] "1384"
[320] "9948"
[321] "3945"
[322] "160"
[323] "84823"
[324] "3188"
[325] "6426"
[326] "6428"
[327] "55210"
[328] "118"
[329] "23597"
[330] "54927"
[331] "25824"
[332] "3608"
[333] "5708"
[334] "10492"
[335] "641371"
[336] "2771"
[337] "1397"
[338] "10965"
[339] "749887"
[340] "23180"
[341] "230"
[342] "3954"
[343] "18"
[344] "2805"
[345] "6640"
[346] "4659"
[347] "5239"
[348] "1994"
[349] "64087"
[350] "7001"
[351] "10455"
[352] "8802"
[353] "224"
[354] "7317"
[355] "80221"
[356] "54504"
[357] "29119"
[358] "3853"
[359] "5859"
[360] "4904"
[361] "4641"
[362] "10469"
[363] "1655"
[364] "7871"
[365] "5161"
[366] "6566"
[367] "7082"
[368] "8661"
[369] "5962"
[370] "10643"
[371] "5589"
[372] "3305"
[373] "3421"
[374] "7112"
[375] "10576"
[376] "2969"
[377] "1376"
[378] "1314"
[379] "23065"
[380] "1642"
[381] "9218"
[382] "3852"
[383] "10452"
[384] "5499"
[385] "1158"
[386] "4200"
[387] "5095"
[388] "23203"
[389] "36"
[390] "57805"
[391] "1632"
[392] "64091"
[393] "28976"
[394] "50808"
[395] "387"
[396] "1653"
[397] "25813"
[398] "7360"
[399] "9217"
[400] "7402"
[401] "7111"
[402] "8087"
[403] "1981"
[404] "84263"
[405] "2110"
[406] "10157"
[407] "10211"
[408] "204"
[409] "6130"
[410] "2180"
[411] "80017"
[412] "3998"
[413] "3308"
[414] "3712"
[415] "10694"
[416] "2232"
[417] "5862"
[418] "10147"
[419] "8508"
[420] "7203"
[421] "2782"
[422] "6128"
[423] "51056"
[424] "51520"
[425] "3837"
[426] "3679"
[427] "84896"
[428] "4513"
[429] "813"
[430] "6191"
[431] "10160"
[432] "79784"
[433] "2017"
[434] "56922"
[435] "221092"
[436] "92140"
[437] "144100"
[438] "800"
[439] "3842"
[440] "6189"
[441] "373156"
[442] "2319"
[443] "7175"
[444] "1429"
[445] "6390"
[446] "23078"
[447] "6520"
[448] "8338"
[449] "7155"
[450] "10291"
[451] "4043"
[452] "55157"
[453] "9927"
[454] "5501"
[455] "84675"
[456] "1464"
[457] "1829"
[458] "444"
[459] "8050"
[460] "10992"
[461] "587"
[462] "284119"
[463] "84940"
[464] "1410"
[465] "3276"
[466] "60681"
[467] "494115"
[468] "989"
[469] "4905"
[470] "6129"
[471] "5163"
[472] "3054"
[473] "8801"
[474] "23450"
[475] "515"
[476] "2720"
[477] "23654"
[478] "2521"
[479] "1654"
[480] "5236"
[481] "10960"
[482] "11112"
[483] "285025"
[484] "55750"
[485] "1072"
[486] "817"
[487] "10575"
[488] "4131"
[489] "3913"
[490] "81567"
[491] "6125"
[492] "84700"
[493] "3146"
[494] "5576"
[495] "2783"
[496] "5861"
[497] "8663"
[498] "35"
[499] "10972"
[500] "56945"
[501] "7531"
[502] "26986"
[503] "3921"
[504] "10651"
[505] "9512"
[506] "7818"
[507] "89941"
[508] "55967"
[509] "5033"
[510] "4162"
[511] "4047"
[512] "7158"
[513] "85476"
[514] "283820"
[515] "9230"
[516] "3872"
[517] "10857"
[518] "4831; 654364"
[519] "421"
[520] "1615"
[521] "51449"
[522] "5682"
[523] "55037"
[524] "593"
[525] "2548"
[526] "5837"
[527] "1374"
[528] "10890"
[529] "1200"
[530] "7086"
[531] "23420"
[532] "223"
[533] "27020"
[534] "161"
[535] "10644"
[536] "3855"
[537] "23646"
[538] "6122"
[539] "2026"
[540] "51493"
[541] "7841"
[542] "57136"
[543] "80142"
[544] "57158"
[545] "9987"
[546] "1627"
[547] "1605"
[548] "23603"
[549] "11100"
[550] "2997"
[551] "2235"
[552] "10484"
[553] "6132"
[554] "50809"
[555] "10528"
[556] "51097"
[557] "54940"
[558] "5350"
[559] "2091"
[560] "4012"
[561] "8148"
[562] "6203"
[563] "2817"
[564] "10486"
[565] "23020"
[566] "8540"
[567] "51552"
[568] "27068"
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[1947] "8450"
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[1964] "11273"
[1965] "3692"
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[1969] "3908"
[1970] "801; 805; 808"
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[1975] "9961"
[1976] "7353"
[1977] "5050"
[1978] "6263"
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[1980] "221662"
[1981] "64834"
[1982] "122961"
[1983] "10670"
[1984] "64951"
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[1986] "10980"
[1987] "83481"
[1988] "3550"
[1989] "57727"
[1990] "8825"
[1991] "154807"
[1992] "2710"
[1993] "80331"
[1994] "9559"
[1995] "2697"
[1996] "54953"
[1997] "54534"
[1998] "29789"
[1999] "387522; 7335"
[2000] "1460"
[2001] "2519"
[2002] "3839"
[2003] "51218"
[2004] "10713"
[2005] "57552"
[2006] "984"
[2007] "5371"
[2008] "10573"
[2009] "79572"
[2010] "7436"
[2011] "6733"
[2012] "79714"
[2013] "64924"
[2014] "348995"
[2015] "28969"
[2016] "10434"
[2017] "345778"
[2018] "81887"
[2019] "1284"
[2020] "56255"
[2021] "4920"
[2022] "8451"
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[2024] "83460"
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[2090] "10197"
[2091] "10005"
[2092] "84908"
[2093] "10280"
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[2095] "3992"
[2096] "4154"
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[2099] "7138"
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[2205] "9818"
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[3324] "2186" # Fusion proteins in ENTREZ ids. Therefore, need to split them up
# vector to split
my_vector_test <- DE_ENTREZ_Padj
# Split the elements of the vector on semicolons
split_vector <- strsplit(my_vector_test, split = ";")
# Unlist the split vector
new_vector_ENTREZ <- unlist(split_vector)
# Do the same for background
back_vector_test <- Background_ENTREZ
# Split the elements of the vector on semicolons
split_vector <- strsplit(back_vector_test, split = ";")
# Unlist the split vector
back_new_vector_ENTREZ <- unlist(split_vector)
new_vector_ENTREZ %>% length()[1] 211EnrichPathobj <- ReactomePA::enrichPathway(
new_vector_ENTREZ,
organism = "human",
pvalueCutoff = 0.05,
pAdjustMethod = "BH",
qvalueCutoff = 0.05,
universe = back_new_vector_ENTREZ,
minGSSize = 2,
maxGSSize = 500,
readable = FALSE
)
EnrichPathobj#
# over-representation test
#
#...@organism human
#...@ontology Reactome
#...@keytype ENTREZID
#...@gene chr [1:211] "3008" "4869" "4691" "3006" "6124" "3849" "10521" "10399" ...
#...pvalues adjusted by 'BH' with cutoff <0.05
#...65 enriched terms found
'data.frame': 65 obs. of 9 variables:
$ ID : chr "R-HSA-8868773" "R-HSA-6791226" "R-HSA-72312" "R-HSA-2408557" ...
$ Description: chr "rRNA processing in the nucleus and cytosol" "Major pathway of rRNA processing in the nucleolus and cytosol" "rRNA processing" "Selenocysteine synthesis" ...
$ GeneRatio : chr "60/140" "59/140" "61/140" "50/140" ...
$ BgRatio : chr "109/2484" "106/2484" "118/2484" "75/2484" ...
$ pvalue : num 4.20e-51 1.48e-50 8.65e-50 5.41e-48 1.52e-47 ...
$ p.adjust : num 1.96e-48 3.45e-48 1.34e-47 6.30e-46 1.15e-45 ...
$ qvalue : num 1.63e-48 2.86e-48 1.12e-47 5.24e-46 9.57e-46 ...
$ geneID : chr "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/6193/6"| __truncated__ "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/6193/6"| __truncated__ "4691/6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/6193/6"| __truncated__ "6124/6188/6130/6191/6189/3921/6122/6132/6203/6208/6222/6194/6205/6155/6224/6139/6156/4736/6210/6133/6193/6154/6"| __truncated__ ...
$ Count : int 60 59 61 50 50 50 51 50 50 50 ...
#...Citation
Guangchuang Yu, Qing-Yu He. ReactomePA: an R/Bioconductor package for
reactome pathway analysis and visualization. Molecular BioSystems
2016, 12(2):477-479 # summary of the result that most people use
plot(barplot(EnrichPathobj, showCategory = 20))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# View the top enriched GO terms as a tibble
GO_Tibble <- EnrichPathobj %>% as_tibble()
GO_Tibble# A tibble: 65 × 9
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
<chr> <chr> <chr> <chr> <dbl> <dbl> <dbl> <chr> <int>
1 R-HSA-… rRNA proce… 60/140 109/24… 4.20e-51 1.96e-48 1.63e-48 4691/… 60
2 R-HSA-… Major path… 59/140 106/24… 1.48e-50 3.45e-48 2.86e-48 4691/… 59
3 R-HSA-… rRNA proce… 61/140 118/24… 8.65e-50 1.34e-47 1.12e-47 4691/… 61
4 R-HSA-… Selenocyst… 50/140 75/2484 5.41e-48 6.30e-46 5.24e-46 6124/… 50
5 R-HSA-… Peptide ch… 50/140 76/2484 1.52e-47 1.15e-45 9.57e-46 6124/… 50
6 R-HSA-… Viral mRNA… 50/140 76/2484 1.52e-47 1.15e-45 9.57e-46 6124/… 50
7 R-HSA-… Nonsense M… 51/140 80/2484 1.73e-47 1.15e-45 9.57e-46 6124/… 51
8 R-HSA-… Eukaryotic… 50/140 77/2484 4.19e-47 2.17e-45 1.80e-45 6124/… 50
9 R-HSA-… Response o… 50/140 77/2484 4.19e-47 2.17e-45 1.80e-45 6124/… 50
10 R-HSA-… Eukaryotic… 50/140 80/2484 7.57e-46 3.53e-44 2.93e-44 6124/… 50
# ℹ 55 more rows# Arrange by adjusted p value
GO_Tibble <- GO_Tibble %>%
arrange(desc(p.adjust))
# Factor by P.adjusted value
GO_Tibble$Description <- factor(GO_Tibble$Description, levels = GO_Tibble$Description[order(GO_Tibble$p.adjust)])
# Get P value for consistent gradient fill
Gradient_value <- GO_Tibble$qvalue %>% median()
# Visualize the total enriched GO terms using a vertical bar plot
ggplot(data = GO_Tibble, aes(x = -log(p.adjust), y = reorder(Description, -log(p.adjust)))) +
geom_bar(stat = "identity") +
geom_bar(stat = "identity", fill = "#4B9CD3")+
labs(x = "-log(p-adj)",
y = "Molecular Functions",
fill = "P.adjusted",
title = "GO enrichment analysis") +
theme_minimal() +
theme(axis.text.x = element_text(angle = 45, hjust = 1))+
xlim(c(0,120))
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* - Read in and wrangle RNA-Seq data ####
#### RNA-Seq Wrangling ####
# Get data
RNA_Seq_Top_Table <- read_csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/RNA_Seq/Doxtoplist.csv", col_names = TRUE, row.names(1))New names:
Rows: 28168 Columns: 9
── Column specification
──────────────────────────────────────────────────────── Delimiter: "," chr
(4): ...1, time, id, SYMBOL dbl (5): ENTREZID, logFC, AveExpr, P.Value,
adj.P.Val
ℹ Use `spec()` to retrieve the full column specification for this data. ℹ
Specify the column types or set `show_col_types = FALSE` to quiet this message.
• `` -> `...1`RNA_Seq_Top_Table %>% dim()[1] 28168 9# Group the 24hr data together
RNA_Seq_Top_Table_24hr <- RNA_Seq_Top_Table %>% dplyr::filter(time == "24_hours")
RNA_Seq_Top_Table_24hr # A tibble: 14,084 × 9
...1 time id ENTREZID SYMBOL logFC AveExpr P.Value adj.P.Val
<chr> <chr> <chr> <dbl> <chr> <dbl> <dbl> <dbl> <dbl>
1 1643...1 24_hours DOX 1643 DDB2 -2.59 5.19 1.74e-28 2.44e-24
2 8337...2 24_hours DOX 8337 H2AC18 -3.00 4.86 1.17e-23 8.25e-20
3 7803...3 24_hours DOX 7803 PTP4A1 -1.90 7.66 4.55e-23 1.47e-19
4 132...4 24_hours DOX 132 ADK -2.06 5.18 5.62e-23 1.47e-19
5 85459...5 24_hours DOX 85459 CEP295 2.01 4.05 5.82e-23 1.47e-19
6 723790...6 24_hours DOX 723790 H2AC19 -2.95 4.87 6.28e-23 1.47e-19
7 29965...7 24_hours DOX 29965 CDIP1 -2.62 7.29 5.28e-22 1.06e-18
8 8493...8 24_hours DOX 8493 PPM1D -2.00 5.53 2.99e-21 5.26e-18
9 4488...9 24_hours DOX 4488 MSX2 -3.08 4.33 3.39e-21 5.30e-18
10 25861...10 24_hours DOX 25861 WHRN -3.79 3.77 3.76e-21 5.30e-18
# ℹ 14,074 more rows# Generate q values for the 24hr Dox toptable
qobj <- qvalue(RNA_Seq_Top_Table_24hr$P.Value)
adj_q_values <- qobj$qvalues
RNA_Seq_Top_Table_24hr$adj_q_values <- adj_q_values
RNA_Seq_Top_Table_24hr# A tibble: 14,084 × 10
...1 time id ENTREZID SYMBOL logFC AveExpr P.Value adj.P.Val
<chr> <chr> <chr> <dbl> <chr> <dbl> <dbl> <dbl> <dbl>
1 1643...1 24_hours DOX 1643 DDB2 -2.59 5.19 1.74e-28 2.44e-24
2 8337...2 24_hours DOX 8337 H2AC18 -3.00 4.86 1.17e-23 8.25e-20
3 7803...3 24_hours DOX 7803 PTP4A1 -1.90 7.66 4.55e-23 1.47e-19
4 132...4 24_hours DOX 132 ADK -2.06 5.18 5.62e-23 1.47e-19
5 85459...5 24_hours DOX 85459 CEP295 2.01 4.05 5.82e-23 1.47e-19
6 723790...6 24_hours DOX 723790 H2AC19 -2.95 4.87 6.28e-23 1.47e-19
7 29965...7 24_hours DOX 29965 CDIP1 -2.62 7.29 5.28e-22 1.06e-18
8 8493...8 24_hours DOX 8493 PPM1D -2.00 5.53 2.99e-21 5.26e-18
9 4488...9 24_hours DOX 4488 MSX2 -3.08 4.33 3.39e-21 5.30e-18
10 25861...10 24_hours DOX 25861 WHRN -3.79 3.77 3.76e-21 5.30e-18
# ℹ 14,074 more rows
# ℹ 1 more variable: adj_q_values <dbl>sum(RNA_Seq_Top_Table_24hr$adj_q_values < 0.05 & RNA_Seq_Top_Table_24hr$logFC > 0 )[1] 4143sum(RNA_Seq_Top_Table_24hr$adj_q_values < 0.05 & RNA_Seq_Top_Table_24hr$logFC < 0 )[1] 4119# Group the 3hr data together
RNA_Seq_Top_Table_3hr <- RNA_Seq_Top_Table %>% dplyr::filter(time == "3_hours" )24 hr Plots
# Basic workflow for visualizing. and interpreting genes for 24 hr timepoint
RNA_Seq_Top_Table_24hr# A tibble: 14,084 × 10
...1 time id ENTREZID SYMBOL logFC AveExpr P.Value adj.P.Val
<chr> <chr> <chr> <dbl> <chr> <dbl> <dbl> <dbl> <dbl>
1 1643...1 24_hours DOX 1643 DDB2 -2.59 5.19 1.74e-28 2.44e-24
2 8337...2 24_hours DOX 8337 H2AC18 -3.00 4.86 1.17e-23 8.25e-20
3 7803...3 24_hours DOX 7803 PTP4A1 -1.90 7.66 4.55e-23 1.47e-19
4 132...4 24_hours DOX 132 ADK -2.06 5.18 5.62e-23 1.47e-19
5 85459...5 24_hours DOX 85459 CEP295 2.01 4.05 5.82e-23 1.47e-19
6 723790...6 24_hours DOX 723790 H2AC19 -2.95 4.87 6.28e-23 1.47e-19
7 29965...7 24_hours DOX 29965 CDIP1 -2.62 7.29 5.28e-22 1.06e-18
8 8493...8 24_hours DOX 8493 PPM1D -2.00 5.53 2.99e-21 5.26e-18
9 4488...9 24_hours DOX 4488 MSX2 -3.08 4.33 3.39e-21 5.30e-18
10 25861...10 24_hours DOX 25861 WHRN -3.79 3.77 3.76e-21 5.30e-18
# ℹ 14,074 more rows
# ℹ 1 more variable: adj_q_values <dbl># 1. Create a column to threshold adjusted P-values/q-values
RNA_24hr_Dox_toptable_Threshold_0.05 <- RNA_Seq_Top_Table_24hr %>% mutate(threshold_P = adj.P.Val < 0.05)
# 2. Do the volcano plot
ggplot(RNA_24hr_Dox_toptable_Threshold_0.05)+
geom_point(mapping = aes(x = logFC, y = -log10(adj.P.Val), color = threshold_P ))+
xlab("log2FC")+
ylab("-log10 adjusted p-value")+
ylim(0, 25)+
xlim(-8, 8)+
theme(legend.position = "none",
plot.title = element_text(size = rel(1.5), hjust = 0.5),
axis.title = element_text(size = rel(1.25)))+
theme_bw()
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Volcano plot with labels
ggplot(RNA_24hr_Dox_toptable_Threshold_0.05)+
geom_point(mapping = aes(x = logFC, y = -log10(adj.P.Val), color = threshold_P))+
geom_text(mapping = aes(x = logFC, y = -log10(adj.P.Val), label = SYMBOL),
hjust = -0.1, vjust = -0.1, check_overlap = TRUE, size = 3)+
xlab("log2FC")+
ylab("-log10 adjusted p-value")+
ylim(0, 30)+
xlim(-10, 10)+
theme(legend.position = "none",
plot.title = element_text(size = rel(1.5), hjust = 0.5),
axis.title = element_text(size = rel(1.25)))+
theme_bw()Warning: Removed 70 rows containing missing values (`geom_text()`).
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
RNA-Seq + proteomic sign test Next to do
# Use the ensembl dataset
mart <- useMart("ensembl", dataset = "hsapiens_gene_ensembl")
# vector of Uniprot IDs
uniprot_ids <- toptable_Dupcor %>% rownames()
uniprot_ids %>% length()[1] 3384# Get the corresponding ENTREZ IDs
results_Pro <- getBM(filters = "uniprotswissprot",
attributes = c("uniprotswissprot", "hgnc_symbol"),
values = uniprot_ids,
mart = mart)
# Get the corresponding SYMBOLs
results_RNA <- getBM(filters = "hgnc_symbol",
attributes = c("entrezgene_id","uniprotswissprot", "hgnc_symbol"),
values = RNA_24hr_Dox_toptable_Threshold_0.05$SYMBOL,
mart = mart)
# Simplify Proteomic DF
Pro_DF <- data.frame( uniprotswissprot = rownames(toptable_Dupcor), Pro_LogFC = toptable_Dupcor$logFC, Pro_Pval = toptable_Dupcor$adj.P.Val )
Joined_ProDF_results_Pro <- full_join(Pro_DF, results_Pro, by = "uniprotswissprot")
Joined_ProDF_results_Pro <- Joined_ProDF_results_Pro %>% na.omit()
# Simplify RNA DF
RNA_DF <- data.frame( hgnc_symbol = RNA_24hr_Dox_toptable_Threshold_0.05$SYMBOL, RNA_LogFC = RNA_24hr_Dox_toptable_Threshold_0.05$logFC, RNA_Pval = RNA_24hr_Dox_toptable_Threshold_0.05$adj.P.Val )
RNA_DF %>% head() hgnc_symbol RNA_LogFC RNA_Pval
1 DDB2 -2.593915 2.444720e-24
2 H2AC18 -3.004897 8.254799e-20
3 PTP4A1 -1.902640 1.473790e-19
4 ADK -2.059920 1.473790e-19
5 CEP295 2.008745 1.473790e-19
6 H2AC19 -2.947133 1.473790e-19Joined_ProDF_results_Pro_RNA_DF <- full_join(Joined_ProDF_results_Pro, RNA_DF, by = "hgnc_symbol")
Joined_ProDF_results_Pro_RNA_DF_NAomit <- Joined_ProDF_results_Pro_RNA_DF %>% na.omit()
Results_RNA_DF_Pro_DF_Merged_NAomit <- data.frame(uniprotswissprot = Joined_ProDF_results_Pro_RNA_DF_NAomit$uniprotswissprot,
hgnc_symbol =Joined_ProDF_results_Pro_RNA_DF_NAomit$hgnc_symbol ,
RNA_LogFC = Joined_ProDF_results_Pro_RNA_DF_NAomit$RNA_LogFC,
RNA_Pval = Joined_ProDF_results_Pro_RNA_DF_NAomit$RNA_Pval,
Pro_LogFC = Joined_ProDF_results_Pro_RNA_DF_NAomit$Pro_LogFC,
Pro_Pval = Joined_ProDF_results_Pro_RNA_DF_NAomit$Pro_Pval)
Results_RNA_DF_Pro_DF_Merged_NAomit %>% head() uniprotswissprot hgnc_symbol RNA_LogFC RNA_Pval Pro_LogFC Pro_Pval
1 Q15327 ANKRD1 0.542369649 0.3495016 -3.553817 6.951913e-05
2 O76021 RSL1D1 -0.316532413 0.0903693 -2.141093 2.443330e-04
3 Q96LW7 CARD19 -0.376258841 0.1269744 -1.634296 3.034614e-04
4 Q969Q1 TRIM63 -0.688160365 0.1389441 -4.342380 3.918893e-04
5 P19388 POLR2E 0.183353536 0.1788005 -1.165897 3.940743e-04
6 O43159 RRP8 0.001877949 0.9922191 -2.109689 8.142856e-04Sign Testing
# Add a new column to the data frame indicating whether the signs of Pro_LogFC and RNA_LogFC match
Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match <- sign(Results_RNA_DF_Pro_DF_Merged_NAomit$RNA_LogFC) == sign(Results_RNA_DF_Pro_DF_Merged_NAomit$Pro_LogFC)
Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match [1] FALSE TRUE TRUE TRUE FALSE FALSE FALSE TRUE FALSE FALSE TRUE FALSE
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[3277] FALSE FALSE# Calculate the proportion of matches
proportion_sign_matches <- mean(Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match)
print(proportion_sign_matches)[1] 0.4603417# Fit linear model
model_LogFC <- lm(RNA_LogFC ~ Pro_LogFC, data = Results_RNA_DF_Pro_DF_Merged_NAomit)
# Get R-squared
r2 <- summary(model_LogFC)$r.squared
r2[1] 0.01282524#------ Plot for both same sign and not same sign
ggplot(Results_RNA_DF_Pro_DF_Merged_NAomit, aes(x = Pro_LogFC, y = RNA_LogFC, color = sign_match)) +
geom_point(size = 2, alpha = 0.5) +
geom_smooth(method = "lm", se = FALSE, color = "black", linetype = "dashed") +
annotate("text", x = Inf, y = Inf, vjust = 2, hjust = 2,
label = paste("R^2 = ", round(r2, digits = 2), sep = ""),
color = "black") +
scale_color_manual(values = c("red", "blue")) +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
theme_bw()`geom_smooth()` using formula = 'y ~ x'
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#------ Plot for same sign
SAME_SIGN <- Results_RNA_DF_Pro_DF_Merged_NAomit[Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match == TRUE, ]
# Fit linear model
model_LogFC <- lm(RNA_LogFC ~ Pro_LogFC, data = SAME_SIGN)
nrow(SAME_SIGN)/nrow(Results_RNA_DF_Pro_DF_Merged_NAomit)[1] 0.4603417# Get R-squared
r2 <- summary(model_LogFC)$r.squared
r2[1] 0.228724ggplot(SAME_SIGN, aes(x = Pro_LogFC, y = RNA_LogFC, color = sign_match)) +
geom_point(size = 2, alpha = 0.5) +
geom_smooth(method = "lm", se = FALSE, color = "black", linetype = "dashed") +
annotate("text", x = Inf, y = Inf, vjust = 2, hjust = 2,
label = paste("R^2 = ", round(r2, digits = 2), sep = ""),
color = "black") +
scale_color_manual(values = c("red", "blue")) +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
theme_bw()`geom_smooth()` using formula = 'y ~ x'
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#------ Plot for opposite signs
OPPOSITE_SIGN <- Results_RNA_DF_Pro_DF_Merged_NAomit[Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match == FALSE, ]
# Fit linear model
model_LogFC <- lm(RNA_LogFC ~ Pro_LogFC, data = OPPOSITE_SIGN)
# Get R-squared
r2 <- summary(model_LogFC)$r.squared
r2[1] 0.2757911ggplot(OPPOSITE_SIGN, aes(x = Pro_LogFC, y = RNA_LogFC, color = sign_match)) +
geom_point(size = 2, alpha = 0.5) +
geom_smooth(method = "lm", se = FALSE, color = "black", linetype = "dashed") +
annotate("text", x = Inf, y = Inf, vjust = 2, hjust = 2,
label = paste("R^2 = ", round(r2, digits = 2), sep = ""),
color = "black") +
scale_color_manual(values = c("red", "blue")) +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
theme_bw()`geom_smooth()` using formula = 'y ~ x'
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Plot for Same sign & DE in both cases
SAME_Sign_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match == TRUE), ]
SAME_Sign_DE_2 <- SAME_Sign_DE[ (SAME_Sign_DE$RNA_Pval < 0.05) & (SAME_Sign_DE$Pro_Pval < 0.05), ]
# Fit linear model
model_LogFC <- lm(RNA_LogFC ~ Pro_LogFC, data = SAME_Sign_DE_2)
# Get R-squared
r2 <- summary(model_LogFC)$r.squared
r2[1] 0.402619ggplot(SAME_Sign_DE_2, aes(x = Pro_LogFC, y = RNA_LogFC, color = sign_match)) +
geom_point(size = 2, alpha = 0.5) +
geom_smooth(method = "lm", se = FALSE, color = "black", linetype = "dashed") +
annotate("text", x = Inf, y = Inf, vjust = 2, hjust = 2,
label = paste("R^2 = ", round(r2, digits = 2), sep = ""),
color = "black") +
scale_color_manual(values = c("red", "blue")) +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
theme_bw()`geom_smooth()` using formula = 'y ~ x'
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Plot for opposite sign & DE
SAME_Sign_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match == FALSE), ]
SAME_Sign_DE_2 <- SAME_Sign_DE[ (SAME_Sign_DE$RNA_Pval < 0.05) & (SAME_Sign_DE$Pro_Pval < 0.05), ]
SAME_Sign_DE_2 %>% dim()[1] 62 7# Fit linear model
model_LogFC <- lm(RNA_LogFC ~ Pro_LogFC, data = SAME_Sign_DE_2)
# Get R-squared
r2 <- summary(model_LogFC)$r.squared
r2[1] 0.5648142ggplot(SAME_Sign_DE_2, aes(x = Pro_LogFC, y = RNA_LogFC, color = sign_match)) +
geom_point(size = 2, alpha = 0.5) +
geom_smooth(method = "lm", se = FALSE, color = "black", linetype = "dashed") +
annotate("text", x = Inf, y = Inf, vjust = 2, hjust = 2,
label = paste("R^2 = ", round(r2, digits = 2), sep = ""),
color = "black") +
scale_color_manual(values = c("red", "blue")) +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
theme_bw()`geom_smooth()` using formula = 'y ~ x'
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
#---------- Plot for DE
RNA_Pro_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$RNA_Pval < 0.05) & (Results_RNA_DF_Pro_DF_Merged_NAomit$Pro_Pval < 0.05), ]
# Fit linear model
model_LogFC <- lm(RNA_LogFC ~ Pro_LogFC, data = RNA_Pro_DE)
# Get R-squared
r2 <- summary(model_LogFC)$r.squared
r2[1] 0.1772525ggplot(RNA_Pro_DE, aes(x = Pro_LogFC, y = RNA_LogFC, color = sign_match)) +
geom_point(size = 2, alpha = 0.5) +
geom_smooth(method = "lm", se = FALSE, color = "black", linetype = "dashed") +
annotate("text", x = Inf, y = Inf, vjust = 2, hjust = 2,
label = paste("R^2 = ", round(r2, digits = 2), sep = ""),
color = "black") +
scale_color_manual(values = c("red", "blue")) +
theme(axis.text.x = element_text(angle = 90, vjust = 0.5, hjust=1)) +
theme_bw()`geom_smooth()` using formula = 'y ~ x'
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GWAS Enrichment Tests
HF_GWAS <- readRDS(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Data_sets/GWAS/HF_geneset.RDS")
CAD_GWAS <- readRDS(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Data_sets/GWAS/CAD_geneset.RDS")
ARR_GWAS <- readRDS(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Data_sets/GWAS/Arr_geneset.RDS")
# Combine data frames into a whole CVD GWAS data set
CVD_GWAS <- rbind(HF_GWAS, CAD_GWAS, ARR_GWAS)
# Get the unique genes from the CVD_GWAS data set
CVD_GWAS_Unique <- CVD_GWAS$hgnc_symbol %>% unique() # Prepare:
# A = number of DE things that are in the GWAS list
# B = number of DE things that are not in the GWAS list
# C = number of expressed things that are in the GWAS list but are not DE
# D = number of expressed things that are not in the GWAS list and are not DE
Expressed_protein <- Results_RNA_DF_Pro_DF_Merged_NAomit$hgnc_symbol
CAD_GWAS_Expressed <- intersect(CAD_GWAS$hgnc_symbol, Expressed_protein)
intersect(Expressed_protein,CAD_GWAS_Expressed ) [1] "GIGYF2" "EDNRA" "SNRPD2" "LDLR" "FBN2" "PALLD"
[7] "PTK7" "HTRA1" "COL4A2" "RDX" "AGPAT4" "FN1"
[13] "ANXA6" "CNPY2" "HSD17B12" "WDR11" "RRBP1" "CTAGE1"
[19] "GOSR2" "NIPSNAP3B" "NDUFAF6" "VPS29" "NOC3L" "APOE"
[25] "MRAS" "FGD6" "KANK2" "TNS1" "GIT2" "NRIP1"
[31] "ACAA2" "GFPT1" "MAT2A" "COMT" "SOD2" "ATP2A2"
[37] "MAP1S" "MYL2" "CDH13" "ATP2B1" "BCAP29" "PAFAH1B1"
[43] "SERPINH1" "PPCS" "MIA3" "BCAS3" "HNRNPUL1" "IGF2BP1"
[49] "SORBS2" "SF3A3" "ATP1B1" "ITGA2" "PDLIM5" "RAC1"
[55] "NEK9" "TMEM106B" "CLINT1" CAD_GWAS_Expressed [1] "ACAA2" "AGPAT4" "ANXA6" "APOE" "ATP1B1" "ATP2A2"
[7] "ATP2B1" "BCAP29" "BCAS3" "CDH13" "CLINT1" "CNPY2"
[13] "COL4A2" "COMT" "CTAGE1" "EDNRA" "FBN2" "FGD6"
[19] "FN1" "GFPT1" "GIGYF2" "GIT2" "GOSR2" "HNRNPUL1"
[25] "HSD17B12" "HTRA1" "IGF2BP1" "ITGA2" "KANK2" "LDLR"
[31] "MAP1S" "MAT2A" "MIA3" "MRAS" "MYL2" "NDUFAF6"
[37] "NEK9" "NIPSNAP3B" "NOC3L" "NRIP1" "PAFAH1B1" "PALLD"
[43] "PDLIM5" "PPCS" "PTK7" "RAC1" "RDX" "RRBP1"
[49] "SERPINH1" "SF3A3" "SNRPD2" "SOD2" "SORBS2" "TMEM106B"
[55] "TNS1" "VPS29" "WDR11" ARR_GWAS_Expressed <- intersect(ARR_GWAS$hgnc_symbol,Expressed_protein)
intersect(Expressed_protein,ARR_GWAS_Expressed ) [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" HF_GWAS_Expressed <- intersect(HF_GWAS$hgnc_symbol, Expressed_protein)
intersect(Expressed_protein,HF_GWAS_Expressed )[1] "GTF2I" "SPEN" "CACNB2" "HSD17B12" "BAG3" "YWHAE" "SYNPO2L"
[8] "ALDH2" "NPC1" HF_GWAS_Expressed[1] "ALDH2" "BAG3" "CACNB2" "GTF2I" "HSD17B12" "NPC1" "SPEN"
[8] "SYNPO2L" "YWHAE" Enrichment Testing
####* --- DE protein ####
# Protein coding universe GWAS
SAME_Sign_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$Pro_Pval <0.05 ), ]
SAME_Sign_DE$hgnc_symbol [1] "ANKRD1" "RSL1D1" "CARD19" "TRIM63" "POLR2E" "RRP8"
[7] "VASN" "DDX5" "QKI" "RBM39" "YBX1" "MYBBP1A"
[13] "UBTF" "TPBG" "PRRC2A" "DDX17" "LARP7" "GTF2I"
[19] "NUCB1" "HDLBP" "IK" "H1-10" "NUMA1" "USP10"
[25] "SMU1" "DDX21" "FADS1" "RCC2" "SLC30A1" "GNL3"
[31] "SH3BP4" "RPL22L1" "BAD" "DDX42" "FADS2" "FAM120A"
[37] "SMC3" "CDC73" "YBX3" "TBL1XR1" "RPSA" "VARS1"
[43] "SPEN" "HNRNPA0" "NOP58" "FKBP5" "PTBP2" "GCSH"
[49] "LSM2" "FNDC3B" "RPL10A" "CTCF" "MTREX" "NDUFA5"
[55] "RPS26" "DDX50" "RPL23A" "ADNP" "GLYR1" "BAIAP2"
[61] "ALPK3" "RPS6" "H1-2" "RPS29" "VAT1" "KDSR"
[67] "SRRM2" "USP28" "RPL26" "MFSD10" "NUCKS1" "PABPN1"
[73] "RPL15" "EXOSC10" "RPS5" "EPB41L5" "POLR2B" "CUX1"
[79] "EXOSC3" "RPS11" "RPS4X" "ARPC1A" "RPL4" "RPL30"
[85] "TBCEL" "ATP6AP2" "RPL34" "MACROH2A2" "GIGYF2" "YTHDF3"
[91] "SERBP1" "RPL17" "GOLIM4" "RPS10" "NCL" "ACLY"
[97] "CDC5L" "CDC42BPB" "NINL" "SIPA1L3" "RPL37A" "TUBB3"
[103] "DDX18" "RPS14" "CREB1" "ACAD8" "HSPA4" "RPL24"
[109] "RPS16" "RPS12" "BNIP3" "THBS1" "ZNF638" "GJA1"
[115] "MRC2" "SNU13" "S1PR1" "CD46" "RPL36A" "PRDX1"
[121] "LIN7C" "RPS17" "RPS18" "PES1" "RPL32" "RPL14"
[127] "CDK12" "RPL27" "EPHA4" "RPS15" "RPS3A" "RPS28"
[133] "RBMS1" "PRMT1" "RPL7A" "RPL35A" "PNN" "NPM1"
[139] "MAP7D3" "TIMMDC1" "DPF3" "MTIF3" "DDX3X" "TRIM54"
[145] "RPL21" "POLR1E" "VCAM1" "RPLP2" "RPL9" "SARNP"
[151] "PPP4C" "LARP4" "MRPL28" "LMOD2" "PLRG1" "UBE2Z"
[157] "RPS25" "RPS24" "MRPS26" "CHTOP" "PABPC1" "DDX47"
[163] "RPL31" "FSCN1" "LGR4" "PABPC4" "ARID2" "MBNL1"
[169] "LRRC10" "CAND2" "PPP1R8" "RPL8" "SLC1A5" "DDX41"
[175] "NAT10" "METTL17" "RPL36" "RPS19" "RACK1" "TP53BP1"
[181] "EXOSC7" "EDNRA" "CWC15" "STX8" "RPS9" "VLDLR"
[187] "RPL27A" "DPP3" "CORO1B" "DMAC2L" "ECSIT" "TKT"
[193] "CCNA1" "RTRAF" "NDUFA8" "RPL36AL" "ST3GAL1" "PAK4"
[199] "CAPRIN1" "G3BP1" "RPS3" "FAM3C" "RPS15A" "TRIM21"
[205] "RPL29" "RPS20" "CHD4" "LRRN4" "SMNDC1" "TFB1M"
[211] "AHSA1" "MAP1LC3B" "TMEM192" "RPL3" "RNMT" "PPP1CC"
[217] "DPYSL2" HF_GWAS$ensembl_gene_id %>% length()[1] 41# HF
#**************************
GWAS_Exp <- intersect(Expressed_protein, HF_GWAS_Expressed)
GWAS_Exp[1] "GTF2I" "SPEN" "CACNB2" "HSD17B12" "BAG3" "YWHAE" "SYNPO2L"
[8] "ALDH2" "NPC1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 2# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE$hgnc_symbol) - A
B[1] 215# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 7# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE$hgnc_symbol)) - C
D[1] 3054# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.4736, df = 1, p-value = 0.2248fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.1155
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.4086789 21.4718469
sample estimates:
odds ratio
4.055648 # Record the gene list
GWAS_List_3 <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp)
GWAS_List_3[1] "GTF2I" "SPEN" colnames(mat) <- c("DE", "~DE")
rownames(mat) <- c("GWAS", "~GWAS")
mat DE ~DE
GWAS 2 7
~GWAS 215 3054table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("GWAS", "Non-GWAS"),
Protein = c("DE", "Non-DE"))))
# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + GWAS", "DE ~ GWAS", "~ DE + GWAS", "~ DE ~ GWAS")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
table Protein
Gene DE Non-DE
GWAS 2 7
Non-GWAS 215 3054# CAD
#**************************
CAD_GWAS$hgnc_symbol %>% length()[1] 279CAD_GWAS_Expressed %>% length()[1] 57GWAS_Exp <- intersect(Expressed_protein, CAD_GWAS_Expressed)
intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()[1] 2# A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 2# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE$hgnc_symbol) - A
B[1] 215# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 55# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE$hgnc_symbol)) - C
D[1] 3006# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.4683, df = 1, p-value = 0.4938# ARR
#**************************
GWAS_Exp <- intersect(Expressed_protein, ARR_GWAS_Expressed)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 5# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE$hgnc_symbol) - A
B[1] 212# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 39# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE$hgnc_symbol)) - C
D[1] 3022# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.93886, df = 1, p-value = 0.3326fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2109
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.5562774 4.7075648
sample estimates:
odds ratio
1.827042 ####* — DE RNA ####
Results_RNA_DF_Pro_DF_Merged_NAomit %>% dim()[1] 3278 7# Protein coding universe GWAS
SAME_Sign_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$RNA_Pval < 0.05 ), ]
SAME_Sign_DE$hgnc_symbol [1] "VASN" "DDX5" "QKI" "YBX1" "MYBBP1A"
[6] "TPBG" "PRRC2A" "DDX17" "H1-10" "USP10"
[11] "SMU1" "RCC2" "SLC30A1" "GNL3" "RPL22L1"
[16] "BAD" "FADS2" "FAM120A" "SMC3" "YBX3"
[21] "FKBP5" "CTCF" "MTREX" "DDX50" "RPL23A"
[26] "ADNP" "BAIAP2" "H1-2" "KDSR" "USP28"
[31] "EXOSC10" "POLR2B" "TBCEL" "MACROH2A2" "YTHDF3"
[36] "RPL17" "RPS10" "ACLY" "TUBB3" "HSPA4"
[41] "GJA1" "SNU13" "S1PR1" "CD46" "CDK12"
[46] "RPS15" "RBMS1" "PNN" "TIMMDC1" "DPF3"
[51] "DDX3X" "TRIM54" "POLR1E" "VCAM1" "MRPL28"
[56] "LMOD2" "UBE2Z" "RPS24" "MRPS26" "CHTOP"
[61] "FSCN1" "LGR4" "PABPC4" "ARID2" "MBNL1"
[66] "LRRC10" "CAND2" "NAT10" "RPS19" "RACK1"
[71] "TP53BP1" "EDNRA" "STX8" "VLDLR" "CORO1B"
[76] "ECSIT" "TKT" "CCNA1" "NDUFA8" "PAK4"
[81] "CAPRIN1" "TRIM21" "RPS20" "CHD4" "TFB1M"
[86] "MAP1LC3B" "PPP1CC" "DPYSL2" "MCM8" "FUCA1"
[91] "STIM1" "GRN" "RPP30" "OXNAD1" "CDIPT"
[96] "ANXA5" "FASTKD2" "AK2" "NOC2L" "PQBP1"
[101] "MRPS6" "DKC1" "WDR43" "RBM20" "KLHL31"
[106] "MRPL4" "SAE1" "MRPS18B" "CNBP" "SMARCA1"
[111] "TNNT1" "SPTLC2" "MTCH1" "OMA1" "MAGOHB"
[116] "HNRNPLL" "CHCHD6" "BOP1" "LRCH4" "SYMPK"
[121] "PYCR2" "TANC2" "INTS3" "CYP51A1" "UPF1"
[126] "ACTC1" "TUBB" "CRAT" "SMARCA5" "MUL1"
[131] "CD59" "TUBA1A" "TUBB6" "STYXL2" "NUCB2"
[136] "AKAP1" "VPS39" "SUPT4H1" "CACNB2" "FBN2"
[141] "HNRNPDL" "FUBP1" "MRPL17" "MACROH2A1" "PALLD"
[146] "ARHGAP1" "MSH6" "ADSL" "EXOSC2" "SORBS3"
[151] "DPYSL3" "ORC2" "SKP1" "SNX2" "GABARAPL2"
[156] "STOM" "SPHKAP" "MLEC" "USP11" "INTS13"
[161] "HSPH1" "TOR1A" "VMA21" "MRPL15" "SLC39A14"
[166] "GTF3C3" "SNRPA1" "XPNPEP1" "KHDRBS1" "EEF1A1"
[171] "REEP4" "MRPL30" "NUDT8" "SLC12A4" "H2AZ2"
[176] "WBP11" "SF1" "GOLGA2" "SMARCA4" "COPS5"
[181] "ATP8A2" "HIP1" "ATPAF2" "DNPEP" "PHF6"
[186] "GORASP1" "FBL" "CSTF3" "EIF3B" "G3BP2"
[191] "PTPRD" "NAPA" "DDB1" "EXOSC8" "TUBA4A"
[196] "CFL1" "MAGI1" "FUS" "TMX4" "TCERG1"
[201] "NDUFB10" "SRSF6" "PEX3" "EZH1" "ZC3H14"
[206] "RDH10" "NDUFV2" "EIF4A3" "NCEH1" "PDS5A"
[211] "ZDHHC13" "HSPA1B" "H1-0" "CDK9" "RPS27"
[216] "GIT1" "TNNI3" "ERAL1" "M6PR" "NXF1"
[221] "SSRP1" "EPHX1" "PIGK" "ARPC2" "FHL1"
[226] "HDAC1" "PRKRA" "KDM3B" "FAM98A" "ERLIN1"
[231] "TAP1" "HIBADH" "MRPL18" "BRI3BP" "ALG9"
[236] "PPIA" "MYOZ2" "ATP5PB" "VIM" "DDX28"
[241] "EIF4A2" "NLGN1" "FABP3" "TM7SF2" "OPLAH"
[246] "HTATSF1" "STBD1" "SFPQ" "NPEPPS" "BAX"
[251] "PAICS" "ACBD3" "GSTZ1" "NPM3" "TP53I3"
[256] "ISYNA1" "DCAF7" "P4HA2" "NAPG" "NAMPT"
[261] "RP2" "FASTKD1" "MRPL32" "EIF3H" "UBQLN1"
[266] "MRPL40" "EIF2B1" "LPGAT1" "CAPN1" "GSR"
[271] "PABPC5" "HNRNPH1" "PLEKHA7" "TMOD1" "SLC31A1"
[276] "LPP" "NONO" "HACD1" "SOD1" "FHOD3"
[281] "LGALS3BP" "RSF1" "REXO2" "UBXN4" "AGPAT4"
[286] "USP15" "LSM14A" "STK11IP" "ILVBL" "SLC25A21"
[291] "AAAS" "PPP1R12B" "DST" "SLC25A15" "USP5"
[296] "FEN1" "SRSF5" "CHCHD3" "SNRNP40" "AHCY"
[301] "TRA2A" "HNRNPD" "GSE1" "NME2" "WDR77"
[306] "MYO1B" "EXD2" "TMEM177" "ABHD12" "DHX29"
[311] "HAT1" "DOCK3" "MRPS17" "ANXA6" "EIF2B3"
[316] "EDC4" "YES1" "TST" "LGALS3" "CASZ1"
[321] "TUBGCP3" "RUFY1" "ARSA" "CELF2" "PRMT5"
[326] "CTSB" "DNAJB4" "GOT1" "SLC35B2" "GLS"
[331] "INTS5" "COQ8A" "PHGDH" "RAB33B" "CISD2"
[336] "PDK2" "DNAJC8" "SMS" "FILIP1" "RETREG3"
[341] "EIF3M" "WHRN" "TMEM109" "IPO7" "GRSF1"
[346] "DNAJC10" "SSR3" "CDS2" "PITRM1" "CASK"
[351] "ATP5F1B" "BAG3" "NAA15" "LBR" "FDXR"
[356] "TENT5A" "PRKAR2B" "VPS45" "SRP72" "COX11"
[361] "TMEM161A" "EXOSC4" "TEX2" "PFN2" "RALA"
[366] "PCCA" "COL18A1" "EHD1" "EXOC8" "ATP1A2"
[371] "ATP5F1A" "WDFY1" "RSU1" "SAP18" "LARS1"
[376] "ETF1" "PRDX6" "ANP32B" "SMARCD3" "TXNDC12"
[381] "BCAT2" "PPP5C" "UFL1" "NDUFA9" "SEPTIN8"
[386] "DAP3" "CNN3" "PDCD6IP" "EMC2" "FAT1"
[391] "NBAS" "POPDC2" "APEH" "GDPD1" "MYL12B"
[396] "CPT2" "MKRN2" "NDUFAF6" "SLC25A3" "CPSF3"
[401] "MFGE8" "CBR4" "CFAP20" "PSMB6" "DDAH1"
[406] "BCAP31" "FLRT2" "RALGAPA2" "NAP1L1" "SNX18"
[411] "TCAP" "DRG1" "LIMS1" "SDHD" "MPP1"
[416] "NCOA3" "PTGFRN" "ACIN1" "DCXR" "ELOC"
[421] "PPM1G" "RAN" "CACHD1" "GNAI1" "METTL15"
[426] "ABCB10" "TAX1BP3" "EPB41L1" "NDUFB4" "AP3M1"
[431] "PRNP" "CRIP2" "PGM5" "NOC3L" "ANP32A"
[436] "NUMB" "ESD" "MYH13" "RAB24" "NADK2"
[441] "METAP1" "SLC30A5" "PRORP" "RDH11" "FDFT1"
[446] "HNRNPR" "TCOF1" "EXOC4" "GNA13" "FKBP4"
[451] "OXSR1" "MAIP1" "NEXN" "PMPCB" "ADH5"
[456] "ACSF2" "ZNF740" "CERS6" "MON1A" "KIFBP"
[461] "AKAP12" "SIGMAR1" "SMARCE1" "MPST" "CASP3"
[466] "WASF1" "SCCPDH" "FHL3" "DCAKD" "ESYT1"
[471] "POGLUT1" "NAV1" "ASCC3" "FXN" "CSTF1"
[476] "YWHAE" "RAP1B" "CDC37" "MMS19" "LIAS"
[481] "RARS1" "AMT" "RPUSD4" "EIF4G2" "ARMC8"
[486] "DNAJB6" "DNM1L" "LIG3" "DEGS1" "DDX24"
[491] "MLIP" "TMEM179B" "SLC35A4" "FRMPD1" "UFSP2"
[496] "DYNLL1" "NEU1" "CCAR2" "TPM1" "DNAH10"
[501] "ZMYM1" "ARF4" "TALDO1" "NFS1" "FOXRED1"
[506] "CS" "ACO2" "RPA2" "SRPK2" "MBOAT7"
[511] "DYNC1I2" "TRA2B" "IBA57" "MCM5" "CYSTM1"
[516] "MFN2" "DMAC2" "TOP2A" "NLRX1" "COA3"
[521] "GPC6" "SIDT2" "MRPL19" "WWC1" "RAB5A"
[526] "BZW2" "MMAA" "BLVRB" "DNAJA1" "IKBIP"
[531] "SRSF2" "RELL1" "EWSR1" "PRKAG2" "GPD1L"
[536] "RTN3" "DLD" "TNS1" "PGRMC2" "MRPL39"
[541] "MRPS34" "FARP1" "PSMB4" "ZWINT" "NUP205"
[546] "ERAP1" "TEX10" "PML" "GIT2" "DCUN1D1"
[551] "ALCAM" "YWHAG" "ICAM1" "PDP1" "CLCN7"
[556] "MRPS27" "TRIP12" "SGPL1" "SCAF11" "IGF2BP2"
[561] "CYP2J2" "ECI2" "CTSL" "IGF2R" "PCNA"
[566] "MBTPS2" "PPHLN1" "RAB10" "DHRS7B" "PPIL1"
[571] "POLDIP2" "RRAGC" "DNAJC5" "PGAM5" "GNAS"
[576] "AMPD2" "EXOC7" "TAMM41" "CUL4A" "PDE12"
[581] "ERGIC2" "VPS26A" "VAMP3" "PTPRZ1" "UBA3"
[586] "PRDX3" "PDXP" "SEC13" "IL1RAP" "PUDP"
[591] "MTUS2" "LAMB1" "HSDL2" "STAU1" "RAD23A"
[596] "MAPK1" "SETD2" "PYGL" "RAB3A" "AHNAK2"
[601] "ADD3" "PGD" "SUCLG1" "NTPCR" "SLC25A24"
[606] "NDUFS4" "RFC5" "CCDC14" "PGP" "LMNB2"
[611] "ELAC2" "DDRGK1" "TMTC3" "IVD" "PNKD"
[616] "THEM6" "CD276" "AGFG1" "MTHFD1" "LTA4H"
[621] "SCN5A" "MCCC2" "AP1B1" "SF3A2" "CDK5RAP2"
[626] "ABAT" "RYR2" "RBM4" "SRPRA" "SUN1"
[631] "MRRF" "NDUFS8" "COG1" "PPP4R3A" "TOMM20"
[636] "DHX15" "EIF2S2" "GFPT1" "TNNT2" "EXOC3L1"
[641] "AKR1A1" "PCID2" "SEC23IP" "SEC31A" "CCDC60"
[646] "STARD7" "ATP2B4" "FABP5" "CTSC" "NUP85"
[651] "TTC7B" "AKAP8L" "ARVCF" "PNPLA6" "RPS27L"
[656] "AK1" "DYNC1H1" "STX16" "HSPB7" "ARHGAP10"
[661] "DTNA" "EPPK1" "TMED5" "RBM28" "NUDT19"
[666] "PRR14L" "ATIC" "ITPRIP" "HAX1" "ATP13A1"
[671] "PRRC1" "CARS2" "POFUT1" "MGME1" "ENDOD1"
[676] "IRF2BPL" "GPRIN3" "MYO18B" "CBX5" "CACYBP"
[681] "SURF1" "MARS1" "CYFIP2" "AK3" "ASPH"
[686] "PSMD14" "HDGF" "HSD17B7" "TOR1AIP1" "CLEC16A"
[691] "CENPJ" "PPA2" "HMOX2" "NHLRC3" "SDC4"
[696] "CENPV" "SNRPD1" "HSPD1" "GOT2" "HNRNPA2B1"
[701] "SNTB2" "VASP" "ECI1" "ZFP14" "CTPS2"
[706] "SLC25A35" "GFUS" "SLC25A4" "LTBP1" "KDM5B"
[711] "EPRS1" "IKBKG" "ALDOC" "RUVBL1" "LRPAP1"
[716] "BAZ1A" "TARS2" "SRRT" "SEC23A" "PALM2AKAP2"
[721] "GIPC1" "TOMM40" "APLP2" "FLOT1" "BAG2"
[726] "MYH7" "ATP2A2" "ATP6V1H" "CSTF2" "ADD2"
[731] "TMED1" "MAP1S" "FAHD1" "KPNA6" "SUGCT"
[736] "TRAM1" "NSUN4" "EOGT" "NAE1" "INPP4A"
[741] "LANCL1" "UBE3A" "ATP6V1D" "STT3A" "SFXN4"
[746] "FAM184A" "YWHAZ" "TIMM29" "CTBS" "GHITM"
[751] "MFF" "SCRN1" "SMYD1" "CISD3" "ACOX3"
[756] "ATP5F1C" "PIEZO1" "PSMD12" "SEPTIN9" "SCYL1"
[761] "ALPK2" "AAK1" "AGRN" "OTUB1" "CBX3"
[766] "CSNK2A1" "NDUFS1" "CYB5A" "TMLHE" "ATP2B1"
[771] "JUP" "MCM3" "SPAG9" "BORCS6" "STAT1"
[776] "PKN2" "PDS5B" "BCAP29" "CSNK1A1" "GSTP1"
[781] "PPP1CA" "RRAGA" "MTA2" "NHSL1" "H2BC21"
[786] "IDH3G" "LCLAT1" "NXT1" "CD55" "ARL2"
[791] "CAP2" "COQ3" "RHOT1" "PA2G4" "LMF2"
[796] "LDB3" "CCDC141" "PDXK" "PALM" "GPAA1"
[801] "GPX1" "ETFB" "MRPL10" "EFNB1" "HSPA9"
[806] "TUFM" "RBM12B" "OGFOD3" "STRN4" "DNAJC13"
[811] "HNRNPA1" "YARS1" "GPC4" "MYEF2" "SEC63"
[816] "NIPSNAP2" "STX5" "TBL2" "SLC25A11" "TXNRD1"
[821] "TP53I11" "MRPL12" "HMGB1" "HTRA2" "NRM"
[826] "CEP290" "PFKFB2" "NNT" "LETMD1" "ABCD1"
[831] "EIF4B" "ADCY5" "DDAH2" "NUP43" "ISCA2"
[836] "NAXD" "AGK" "LAS1L" "SUOX" "SRSF3"
[841] "PGM1" "MYO1C" "CD9" "ACSS2" "MYH2"
[846] "EPM2AIP1" "MESD" "KDELR1" "PGAM2" "YAP1"
[851] "NSDHL" "EEF1D" "ERBB2" "SND1" "NCAM1"
[856] "NUDT9" "HMGCL" "CPOX" "MTA1" "OPA3"
[861] "GMPS" "CTNNA3" "RAB9B" "TAOK2" "MRPS36"
[866] "USP39" "NDRG3" "MIA3" "CTNND2" "ATP6V1E1"
[871] "C8orf82" "SF3B3" "C17orf80" "CAMK2D" "MARF1"
[876] "PLOD1" "APOO" "MRPL44" "CLCC1" "RTN4IP1"
[881] "PREP" "RBBP7" "ABCC1" "MOB1B" "PSMD8"
[886] "MCCC1" "FKBP14" "ZFPL1" "TUBG1" "TMEM143"
[891] "PRPSAP2" "AARS2" "RAB1A" "ACADVL" "DDX1"
[896] "FHL2" "MRPS35" "TECR" "SLC16A7" "PIP5K1C"
[901] "ITGB1BP2" "PSMC3" "BDH1" "ATP5F1D" "RAB6B"
[906] "TOP1" "DNMT1" "IST1" "RAB8A" "IDH1"
[911] "PXMP2" "SH3GLB1" "GTPBP6" "CSNK1D" "CCT3"
[916] "FARSB" "PAFAH1B3" "BLVRA" "BVES" "LMOD1"
[921] "PPT1" "ADRM1" "PARP1" "FAM210A" "LRPPRC"
[926] "ATP6V0A1" "CLCN5" "H2BC5" "KAT2B" "PEX13"
[931] "RBMX" "EZR" "MYH6" "ALDH1B1" "SLC2A4"
[936] "SAR1B" "CYB5R1" "SLC20A2" "PCYOX1L" "VPS13C"
[941] "C1QBP" "SPTLC1" "MTCH2" "BCAS3" "OSTC"
[946] "ATP6V1B2" "MRPL35" "GORASP2" "PLXNA4" "SLC25A12"
[951] "HDGFL3" "APEX1" "TAPT1" "NARS1" "COPS3"
[956] "QDPR" "FMR1" "HNRNPL" "PPP2R5E" "CTR9"
[961] "ACTN2" "CNTNAP1" "AGL" "NPLOC4" "QRSL1"
[966] "TMEM115" "SAFB2" "ESYT2" "PSMD3" "GPAT4"
[971] "HNRNPUL1" "FITM1" "DSC2" "MYOM1" "UNC45B"
[976] "NRP1" "PTGES2" "ITGA3" "BCL2L1" "STK39"
[981] "DLG1" "NCBP1" "RAB31" "CLCN3" "SLC25A20"
[986] "PSMA1" "NSF" "TSG101" "THOC1" "FASTKD5"
[991] "PIGU" "PCM1" "TOP2B" "POGLUT3" "UFD1"
[996] "BAK1" "PANK4" "SPEG" "PLCE1" "BDH2"
[1001] "NUDC" "TTC21B" "GBE1" "LUC7L3" "SRI"
[1006] "SHMT2" "MRPL3" "PTPMT1" "DTL" "AQP1"
[1011] "IGF2BP1" "GAPDHS" "TOLLIP" "ABHD16A" "LAMTOR3"
[1016] "ABCE1" "ANXA4" "OBSCN" "ELMOD2" "SNX6"
[1021] "AUP1" "MRPS2" "ABCB6" "SLC25A19" "SBDS"
[1026] "RCSD1" "ATG9A" "NPC1" "SORBS2" "TMEM63B"
[1031] "CLTC" "CNTLN" "GNAQ" "PTPN1" "SLC7A1"
[1036] "PEX14" "ZNF512B" "ATP1A3" "MMAB" "POGZ"
[1041] "ALDH3A2" "SRP68" "DMD" "CEP83" "RFTN1"
[1046] "NUP155" "CKAP5" "ZW10" "PCDH7" "PACSIN2"
[1051] "MLST8" "HSD17B4" "SLC39A7" "TECRL" "REPS1"
[1056] "FSIP2" "NMT1" "DECR2" "RBM12" "HACD2"
[1061] "PDSS2" "KRT19" "ATAD3B" "VEZT" "GLOD4"
[1066] "CNN1" "CEP162" "NUP93" "STX12" "DHRS4"
[1071] "NEURL4" "ZFP28" "MMP15" "POLG" "FUBP3"
[1076] "SRSF7" "FBLIM1" "XRCC1" "PI4K2A" "GNAI2"
[1081] "RCOR1" "DYNC1LI2" "GNAO1" "H3-3B" "H3-3A"
[1086] "GCAT" "MARS2" "EXOG" "NES" "SLC9A1"
[1091] "HDAC2" "KRT18" "EIF5" "TMEM41A" "THNSL1"
[1096] "PDLIM4" "TMEM126A" "PPAN" "LNPK" "VPS53"
[1101] "METTL7A" "PCDHGB6" "IMMT" "PLA2G15" "FN3K"
[1106] "NUP133" "LYPLA1" "TTN" "HGS" "AGPAT3"
[1111] "MMUT" "PDCD6" "EI24" "SNX27" "DBN1"
[1116] "CLPP" "GSDME" "PTPRK" "GLA" "SRPRB"
[1121] "LETM1" "HIBCH" "PSMA7" "SRRM1" "DGKZ"
[1126] "DLAT" "DHTKD1" "TFB2M" "XPR1" "MAT2B"
[1131] "ARL8B" "TMEM201" "MRPL16" "YIF1B" "SLC26A2"
[1136] "GPX8" "AIMP2" "POR" "RAE1" "IDE"
[1141] "SRSF10" "AP3D1" "GOLGA3" "ACOT11" "PIN1"
[1146] "EIF2B4" "TIMM50" "CLPB" "HSPB8" "ARMCX3"
[1151] "SCFD2" "RBM10" "EMC7" "TRAP1" "LACTB"
[1156] "DARS2" "NUDT21" "VRK1" "FAM169A" "EEF1E1"
[1161] "SYPL1" "C4orf54" "EEF1A2" "EIF4H" "TRMU"
[1166] "ROR2" "SCRIB" "MRM2" "RBM8A" "CNDP2"
[1171] "MTX3" "ATP11A" "ISOC2" "MPRIP" "CDK5RAP3"
[1176] "ARHGEF2" "USP34" "PYCR1" "THYN1" "STARD3NL"
[1181] "ATAD3A" "SLCO3A1" "PALM2AKAP2" "MRPL22" "COQ6"
[1186] "ABHD10" "SLC8A1" "RAB18" "MTPAP" "CTPS1"
[1191] "LDHD" "SUCO" "SLC3A2" "CLIC1" "RTN2"
[1196] "ATP1B2" "KIAA2013" "ARFGAP1" "COPB1" "ARL8A"
[1201] "RAI14" "GNB4" "PMPCA" "MCM2" "MKI67"
[1206] "PPIH" "PREB" "SARS1" "STAT3" "CDH2"
[1211] "GDE1" "LSS" "DPF1" "SRSF1" "DUT"
[1216] "NSFL1C" "DNAJC7" "PYGM" "TBCB" "SPRYD7"
[1221] "SARS2" "HOOK1" "RALB" "PHB2" "EXOC2"
[1226] "DAZAP1" "STX7" "EIF2B5" "TMPO" "TMPO"
[1231] "SNRPD3" "SDHB" "RAB14" "RAB21" "ADPRHL1"
[1236] "AFG3L2" "RTN4" "PAIP1" "NIPSNAP1" "MRM3"
[1241] "KPNA2" "SYNM" "CEPT1" "IGF1R" "L2HGDH"
[1246] "PLXNA1" "WDR18" "NUP98" "SYNPO2" "SCAMP3"
[1251] "DYSF" "PIP4K2A" "SEPHS1" "FAM136A" "DGLUCY"
[1256] "BAG6" "DUOX2" "HARS2" "COX15" "AMACR"
[1261] "CROCC" "PSMD13" "FARS2" "SLC9A6" "ELOA"
[1266] "NAP1L4" "FITM2" "HNRNPAB" "ERG28" "SRC"
[1271] "PFKM" "ANK2" "PHPT1" "MRPL24" "CELF1"
[1276] "ACSL1" "ARMCX2" "NUP88" "MYADM" "LACTB2"
[1281] "PEX16" "NEBL" "DPF2" "GARS1" "FZD2"
[1286] "BCKDHB" "NAT14" "CSPG4" "NIPBL" "MAN1A2"
[1291] "PLXNB2" "MPC1" "FLAD1" "PKP2" "PNKP"
[1296] "ECE1" "ACOT13" "GUF1" "MSRB3" "UQCC1"
[1301] "RAB34" "COPS8" "UBQLN2" "ILK" "CACNB1"
[1306] "BPHL" "NUP160" "CIRBP" "AARS1" "RAB11B"
[1311] "GTPBP4" "PTCD3" "SLC22A18" "PDLIM5" "TMEM256"
[1316] "PPOX" "CEP170B" "YY1" "LLGL1" "SLIT3"
[1321] "TRDN" "ALG12" "ISG15" "NDUFAF5" "CYC1"
[1326] "CFAP57" "KRT8" "DAG1" "XPO7" "ATP5PO"
[1331] "SORT1" "ACP6" "RAB7A" "SMCHD1" "EPHA2"
[1336] "ROR1" "NARS2" "GART" "BZW1" "PTPRS"
[1341] "SLC25A40" "SET" "TEX264" "TNPO1" "TIMM21"
[1346] "CSNK2B" "PCBD1" "NIBAN1" "VWA8" "BCKDK"
[1351] "BCS1L" "THOC3" "ALDH18A1" "AUH" "DMXL2"
[1356] "NDUFA12" "NME4" "VPS41" "XRCC5" "AHNAK"
[1361] "PHLDB2" "PSIP1" "LMNA" "ATP6V0D1" "CYBC1"
[1366] "PSMA4" "HDHD5" "TNIK" "SYNJ2BP" "STX4"
[1371] "MIS18BP1" "LLGL2" "PAK2" "TLN2" "QARS1"
[1376] "OLA1" "HEBP1" "H4C8" "H4C5" "H4C15"
[1381] "H4C14" "TCEA2" "JPH2" "RBMXL1" "ARF3"
[1386] "NFATC4" "SPCS2" "TMX2" "MCM7" "GNPAT"
[1391] "UTRN" "ITSN2" "ERP44" "KPNB1" "HRAS"
[1396] "TMEM106B" "TOMM40L" "UNG" "NUP35" "DHCR7"
[1401] "MAPRE1" "ACSF3" "IGF2BP3" "DHODH" "NFIC"
[1406] "TJP2" "IGDCC4" "BCLAF1" "MRS2" "TEAD3"
[1411] "ABCB7" "CPS1" "NCKAP1" "GNA11" "ARMC10"
[1416] "FAR1" "MRPS9" "TFRC" "CCDC51" "LMAN2L"
[1421] "AASS" "HNRNPC" "MCAM" "MTARC2" "ARMCX1"
[1426] "RCC1L" "TPR" "STXBP3" "IDH3A" "DEK"
[1431] "BPNT1" "PDGFD" "SLC25A10" "B3GLCT" "SDK2"
[1436] "MYO18A" "NCOR1" "TIMM44" "TMEM205" "ABCD3"
[1441] "POLQ" "U2AF2" "DTYMK" "NME3" "CIAPIN1"
[1446] "KPNA3" "PPP6C" "GSTO1" "ACYP2" "MCM6"
[1451] "RAB13" "TPP2" "CNP" "OSBPL8" SAME_Sign_DE %>% dim()[1] 1454 7# HF
#**************************
GWAS_Exp <- intersect(Expressed_protein, HF_GWAS_Expressed)
GWAS_Exp[1] "GTF2I" "SPEN" "CACNB2" "HSD17B12" "BAG3" "YWHAE" "SYNPO2L"
[8] "ALDH2" "NPC1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 4# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE$hgnc_symbol) - A
B[1] 1450# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 5# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE$hgnc_symbol)) - C
D[1] 1819# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.907e-27, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.1987716 4.6718545
sample estimates:
odds ratio
1.003585 # CAD
#**************************
GWAS_Exp <- intersect(Expressed_protein, CAD_GWAS_Expressed)
GWAS_Exp [1] "GIGYF2" "EDNRA" "SNRPD2" "LDLR" "FBN2" "PALLD"
[7] "PTK7" "HTRA1" "COL4A2" "RDX" "AGPAT4" "FN1"
[13] "ANXA6" "CNPY2" "HSD17B12" "WDR11" "RRBP1" "CTAGE1"
[19] "GOSR2" "NIPSNAP3B" "NDUFAF6" "VPS29" "NOC3L" "APOE"
[25] "MRAS" "FGD6" "KANK2" "TNS1" "GIT2" "NRIP1"
[31] "ACAA2" "GFPT1" "MAT2A" "COMT" "SOD2" "ATP2A2"
[37] "MAP1S" "MYL2" "CDH13" "ATP2B1" "BCAP29" "PAFAH1B1"
[43] "SERPINH1" "PPCS" "MIA3" "BCAS3" "HNRNPUL1" "IGF2BP1"
[49] "SORBS2" "SF3A3" "ATP1B1" "ITGA2" "PDLIM5" "RAC1"
[55] "NEK9" "TMEM106B" "CLINT1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 21# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE$hgnc_symbol) - A
B[1] 1433# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 36# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE$hgnc_symbol)) - C
D[1] 1788# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.0353, df = 1, p-value = 0.3089fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.283
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.4018611 1.2874959
sample estimates:
odds ratio
0.7279137 # ARR --- Restricted to most DE genes that are protein coding ( Pval < 0.01)
#**************************
GWAS_Exp <- intersect(Expressed_protein, ARR_GWAS_Expressed)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 26# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE$hgnc_symbol) - A
B[1] 1428# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 18# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE$hgnc_symbol)) - C
D[1] 1806# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 3.3413, df = 1, p-value = 0.06756fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.06556
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.9593184 3.5517673
sample estimates:
odds ratio
1.82643 # Collect enriched genes
GWAS_List_1 <- intersect(SAME_Sign_DE$hgnc_symbol, GWAS_Exp)
GWAS_List_1 [1] "DPF3" "LRRC10" "CAND2" "RBM20" "CASZ1" "YWHAE"
[7] "CUL4A" "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B"
[13] "MYH7" "MYO1C" "CAMK2D" "MYH6" "ANXA4" "TTN"
[19] "USP34" "GNB4" "IGF1R" "PKP2" "SLIT3" "XPO7"
[25] "PHLDB2" "DEK" # Plot result
colnames(mat) <- c("DE", "~DE")
rownames(mat) <- c("GWAS", "~GWAS")
mat DE ~DE
GWAS 26 18
~GWAS 1428 1806table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("GWAS", "Non-GWAS"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
GWAS 26 18
Non-GWAS 1428 1806# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + GWAS", "DE ~ GWAS", "~ DE + GWAS", "~ DE ~ GWAS")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* — DE-Same-Sign ####
# Protein coding universe GWAS
SAME_Sign_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match == TRUE), ]
SAME_Sign_DE_2 <- SAME_Sign_DE[ (SAME_Sign_DE$RNA_Pval < 0.05) & (SAME_Sign_DE$Pro_Pval < 0.05), ]
# HF
#**************************
GWAS_Exp <- intersect(Expressed_protein, HF_GWAS_Expressed)
GWAS_Exp[1] "GTF2I" "SPEN" "CACNB2" "HSD17B12" "BAG3" "YWHAE" "SYNPO2L"
[8] "ALDH2" "NPC1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE_2$hgnc_symbol) - A
B[1] 26# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 9# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE_2$hgnc_symbol)) - C
D[1] 3243# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 2.4696e-25, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.00000 66.67481
sample estimates:
odds ratio
0 # CAD
#**************************
GWAS_Exp <- intersect(Expressed_protein, CAD_GWAS_Expressed)
GWAS_Exp [1] "GIGYF2" "EDNRA" "SNRPD2" "LDLR" "FBN2" "PALLD"
[7] "PTK7" "HTRA1" "COL4A2" "RDX" "AGPAT4" "FN1"
[13] "ANXA6" "CNPY2" "HSD17B12" "WDR11" "RRBP1" "CTAGE1"
[19] "GOSR2" "NIPSNAP3B" "NDUFAF6" "VPS29" "NOC3L" "APOE"
[25] "MRAS" "FGD6" "KANK2" "TNS1" "GIT2" "NRIP1"
[31] "ACAA2" "GFPT1" "MAT2A" "COMT" "SOD2" "ATP2A2"
[37] "MAP1S" "MYL2" "CDH13" "ATP2B1" "BCAP29" "PAFAH1B1"
[43] "SERPINH1" "PPCS" "MIA3" "BCAS3" "HNRNPUL1" "IGF2BP1"
[49] "SORBS2" "SF3A3" "ATP1B1" "ITGA2" "PDLIM5" "RAC1"
[55] "NEK9" "TMEM106B" "CLINT1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE_2$hgnc_symbol) - A
B[1] 26# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 57# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE_2$hgnc_symbol)) - C
D[1] 3195# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.3975e-26, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.000000 8.807611
sample estimates:
odds ratio
0 # ARR --- Restricted to most DE genes that are protein coding ( Pval < 0.01)
#**************************
GWAS_Exp <- intersect(Expressed_protein, ARR_GWAS_Expressed)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE_2$hgnc_symbol) - A
B[1] 26# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 44# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE_2$hgnc_symbol)) - C
D[1] 3208# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 5.7723e-26, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.0000 11.5501
sample estimates:
odds ratio
0 ####* — DE-Opposite-Sign ####
# Protein coding universe GWAS
SAME_Sign_DE <- Results_RNA_DF_Pro_DF_Merged_NAomit[(Results_RNA_DF_Pro_DF_Merged_NAomit$sign_match == FALSE), ]
SAME_Sign_DE_2 <- SAME_Sign_DE[ (SAME_Sign_DE$RNA_Pval < 0.05) & (SAME_Sign_DE$Pro_Pval < 0.05), ]
# HF
#**************************
GWAS_Exp <- intersect(Expressed_protein, HF_GWAS_Expressed)
GWAS_Exp[1] "GTF2I" "SPEN" "CACNB2" "HSD17B12" "BAG3" "YWHAE" "SYNPO2L"
[8] "ALDH2" "NPC1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE_2$hgnc_symbol) - A
B[1] 62# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 9# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE_2$hgnc_symbol)) - C
D[1] 3207# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 5.8352e-29, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.00000 26.80925
sample estimates:
odds ratio
0 # CAD
#**************************
GWAS_Exp <- intersect(Expressed_protein, CAD_GWAS_Expressed)
GWAS_Exp [1] "GIGYF2" "EDNRA" "SNRPD2" "LDLR" "FBN2" "PALLD"
[7] "PTK7" "HTRA1" "COL4A2" "RDX" "AGPAT4" "FN1"
[13] "ANXA6" "CNPY2" "HSD17B12" "WDR11" "RRBP1" "CTAGE1"
[19] "GOSR2" "NIPSNAP3B" "NDUFAF6" "VPS29" "NOC3L" "APOE"
[25] "MRAS" "FGD6" "KANK2" "TNS1" "GIT2" "NRIP1"
[31] "ACAA2" "GFPT1" "MAT2A" "COMT" "SOD2" "ATP2A2"
[37] "MAP1S" "MYL2" "CDH13" "ATP2B1" "BCAP29" "PAFAH1B1"
[43] "SERPINH1" "PPCS" "MIA3" "BCAS3" "HNRNPUL1" "IGF2BP1"
[49] "SORBS2" "SF3A3" "ATP1B1" "ITGA2" "PDLIM5" "RAC1"
[55] "NEK9" "TMEM106B" "CLINT1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 1# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE_2$hgnc_symbol) - A
B[1] 61# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 56# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE_2$hgnc_symbol)) - C
D[1] 3160# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.4172e-29, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.02264808 5.56715786
sample estimates:
odds ratio
0.9250796 # ARR --- Restricted to most DE genes that are protein coding ( Pval < 0.05)
#**************************
GWAS_Exp <- intersect(Expressed_protein, ARR_GWAS_Expressed)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp) %>% length()
A[1] 3# B = number of DE gene/proteins that are not in the GWAS list
B <- length(SAME_Sign_DE_2$hgnc_symbol) - A
B[1] 59# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 41# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(SAME_Sign_DE_2$hgnc_symbol)) - C
D[1] 3175# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 3.4531, df = 1, p-value = 0.06313fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.04929
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.7581648 12.8969707
sample estimates:
odds ratio
3.934371 # Record the genes in this set
GWAS_List_2 <- intersect(SAME_Sign_DE_2$hgnc_symbol, GWAS_Exp)
GWAS_List_2[1] "DPF3" "LRRC10" "CAND2" # Plot result
colnames(mat) <- c("DE", "~DE")
rownames(mat) <- c("GWAS", "~GWAS")
mat DE ~DE
GWAS 3 41
~GWAS 59 3175table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("GWAS", "Non-GWAS"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
GWAS 3 41
Non-GWAS 59 3175# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + GWAS", "DE ~ GWAS", "~ DE + GWAS", "~ DE ~ GWAS")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* — Divergent sets ####
# Calculate the deltaLogFC and plot dstribution and define quantile sets
New_RNA_PRO_DF <- Results_RNA_DF_Pro_DF_Merged_NAomit %>% mutate(delta_logFC = abs(RNA_LogFC - Pro_LogFC))
New_RNA_PRO_DF$delta_logFC %>% hist()
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
New_RNA_PRO_DF$delta_logFC [1] 4.0961864246 1.8245604847 1.2580368818 3.6542200096 1.3492501561
[6] 2.1115671749 3.3858026389 0.4017811005 3.0204363862 1.0569056170
[11] 0.5956266202 2.8271043027 1.0720761781 2.5718561759 1.8116489603
[16] 1.7788574655 1.0623471286 0.9322249767 2.5965406701 1.0786949217
[21] 1.0693304218 2.1865598321 1.4339970353 1.3506158167 0.4847919072
[26] 1.1456024818 1.1043775767 2.7925565575 2.9808919211 2.0825481592
[31] 1.6596221669 4.0238075319 1.8705818769 0.5830719704 4.4937132950
[36] 2.2164881676 2.0319061085 1.1499372980 0.6125415096 0.7944301004
[41] 0.7488775917 0.2881598776 1.4283475860 0.9943021551 0.5036262448
[46] 1.8966704320 1.2681497485 0.6386222300 2.0408582802 1.1039491437
[51] 1.0563313463 0.3792885928 1.2838035761 0.9504383179 1.6779040891
[56] 0.4696977730 0.5771483474 1.6367045733 0.9585857204 2.7709596064
[61] 1.7262253230 0.9300022891 0.4289246355 0.4146200045 0.4022706827
[66] 2.2560273217 0.6569515831 1.9277510943 0.6514508255 0.5465574799
[71] 1.1617534182 0.5170318875 0.2338491604 2.4411232407 0.8935294347
[76] 1.1820592459 0.6048774818 0.9381489554 0.8463901301 0.5622511342
[81] 0.4390906565 0.3394132474 0.7029390562 0.6004303130 0.2675113048
[86] 2.3755343466 0.8385777451 1.1065956371 0.8019510352 0.2027651810
[91] 1.1219898194 0.1618911967 0.3217711153 0.3992141351 0.1357322547
[96] 2.2255342515 0.9061403976 0.2398283522 0.2622166002 1.1514391487
[101] 0.7438978431 2.0312703968 0.9028499346 0.7212781213 0.6033864304
[106] 0.4225422839 1.1918443100 0.5743554200 0.9509630346 0.2081079330
[111] 1.6478580408 2.5963626496 0.8249133018 2.1140912065 1.0303577486
[116] 0.1381957548 2.4348953372 1.9898255541 1.2347437286 1.4514329576
[121] 0.2573932047 0.6145765517 1.1153085877 2.2551695346 0.6237777413
[126] 0.6590585110 1.0266017297 0.3509413277 1.7943590040 0.1794368408
[131] 0.1436771859 1.1256283650 0.1785686990 0.5313770133 0.6118603269
[136] 0.7045547385 1.2318804961 0.7351212622 0.9966578808 0.1797829579
[141] 2.4116868315 1.3993020743 0.0589645654 2.5225175350 0.6258914705
[146] 1.9398481990 8.2496045250 0.8922202907 0.0661851593 1.0013223674
[151] 0.2872363091 1.0968810670 1.7703390177 4.3386891070 0.6517052830
[156] 1.4452637773 1.7047915324 0.0510496299 1.7570147195 1.6535316380
[161] 0.1038534142 1.5881436086 0.3699534966 1.4871880284 2.9276321716
[166] 0.8554297998 1.2197640167 2.3098150655 4.8542763314 2.4982115216
[171] 1.3918582030 0.6634011466 2.4016436238 0.8285943367 1.3920527761
[176] 0.7728235367 0.9763530075 0.0388296915 0.9374410006 1.3674012805
[181] 0.7682160954 1.5672016432 0.7372646708 1.6760118176 0.6389544313
[186] 1.3599960709 0.6507742954 0.7334739513 1.3504281732 0.7709955311
[191] 0.0187742951 2.1318429280 3.2389296898 1.2990319320 1.3819921202
[196] 2.5425072877 0.7475279442 2.1182367441 0.8816213225 0.8165990022
[201] 0.3925419454 0.2608770458 0.5840926646 0.0590645196 0.9013298774
[206] 0.1742051833 1.1212854116 2.9054912584 0.9850436811 1.6117922476
[211] 0.6120554792 1.7288181814 0.0121509333 0.7234591770 0.6222823042
[216] 1.0751251707 1.5483678200 0.6140528971 0.1935052167 2.0361900263
[221] 2.5497556940 2.0401661371 1.0173352627 0.1960725269 0.8117561302
[226] 1.0882659197 0.6720459825 0.4471666255 0.5285265951 0.6095108239
[231] 1.0126594882 0.0272387756 1.0336490432 0.2795678046 0.3240474074
[236] 0.5490035332 1.3912534758 1.2008565652 1.1565439417 1.0388870784
[241] 0.4274597726 0.9601706653 1.4286661777 1.5123370274 1.4901815170
[246] 0.1952886553 0.5499380250 0.8569210111 1.1355252630 0.1544830158
[251] 1.7897613341 0.5754078185 0.6281168715 1.1411527025 0.2848291844
[256] 0.7105462668 1.3024958283 1.4784026634 1.0147349707 0.2288354200
[261] 1.9160304873 1.3337056619 3.6088893084 1.2936864318 0.4193074680
[266] 1.4702078995 0.1002639133 1.5992239970 0.7227616602 0.5277908878
[271] 1.3762141950 2.7052523531 1.2711696159 0.9967257695 1.1427673712
[276] 0.3672836055 0.9114985066 0.3551527488 1.9581041479 0.2952231159
[281] 1.6090822687 0.5434863952 0.6400195925 1.0498847263 0.2476688261
[286] 0.4298698331 1.4411009020 2.4804455223 0.7000156209 0.2885562025
[291] 1.0562527408 0.5492382245 0.4164933843 1.0416566643 2.2966012053
[296] 0.8338795360 1.7520973211 1.4628270022 0.6756481469 1.2454612076
[301] 0.2678014884 0.8446364261 0.6748788104 0.4126739472 0.7450055585
[306] 1.5586679419 0.9700978636 0.4701926092 0.7898073280 1.4559312499
[311] 1.4255780971 0.4884584021 0.8192647295 0.5093990770 0.1534768803
[316] 1.8366907266 0.2469816053 1.0227214363 2.0694871726 0.8671986727
[321] 0.1593566477 0.9116493504 1.0837884441 0.4718442541 1.4255132145
[326] 0.8363197297 0.9730680271 1.1885826290 1.7920544443 1.6369138757
[331] 1.7750251420 0.9064474333 1.1479700552 0.6166114858 0.3844253140
[336] 0.4660648282 1.4962553068 1.2326580695 0.6601681234 1.3231125097
[341] 0.4315861844 0.5437635701 1.3133887766 0.5347860096 1.9346508102
[346] 1.1725029359 0.2373727746 0.7989698405 0.9557564075 0.6098487124
[351] 0.1247402619 0.2324234828 0.3183445208 0.4787825806 1.6046548362
[356] 1.8125681573 0.7058888294 0.4867089227 1.6650137602 1.7759311636
[361] 0.0383521199 0.4964674965 0.9101055456 1.2728377167 0.1838056762
[366] 0.9404240368 0.8980586762 0.8164938926 3.9888640664 0.6137257018
[371] 0.5885387124 1.0262596323 0.5996244463 1.4611929199 0.4797714403
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[1476] 0.3113227836 0.9098068057 0.2385877499 1.2323410119 0.6056918188
[1481] 1.2917571967 0.2469824181 0.1604377212 0.5413885289 0.1657225835
[1486] 0.8968508680 0.1131877959 0.7583185468 0.0567323401 0.2249952552
[1491] 0.3989186461 0.1131967318 0.1522282069 0.0512662755 0.4972199689
[1496] 0.4179516810 0.6726604569 0.5547964914 0.1153194587 0.1555315608
[1501] 0.0919404384 0.2574686261 0.2517289456 0.2074888942 1.1718210942
[1506] 0.9949726831 0.1413128467 0.7156847793 1.0084010904 0.5987853664
[1511] 0.1006990162 0.1462107537 0.5688669568 0.5104642812 0.4355724900
[1516] 3.4268831125 0.0997887727 0.3496603559 0.1195833620 0.3169702326
[1521] 0.6522915720 0.2801023443 0.5456960465 0.2125408114 1.4301554469
[1526] 0.5215822024 0.9274822031 0.7706274331 0.0563825998 0.9627568634
[1531] 0.3166793222 0.3823615000 0.3783200016 1.2584894574 0.2083580668
[1536] 0.3012306767 0.3487991383 1.0677668232 0.0816872383 0.2910030553
[1541] 0.7779337760 0.0868198692 0.4594521647 0.0162323105 0.6108661005
[1546] 0.3319752803 0.0488368524 0.9775249570 0.0340543167 1.5584124074
[1551] 0.1702426410 0.2346563614 0.3333316239 2.0708319625 0.2863141751
[1556] 0.1252305977 1.1029349261 0.0113185126 0.0368859787 1.9533180865
[1561] 0.2603375152 1.6430544906 0.3045255174 1.2105151273 0.0235165475
[1566] 0.3619427003 0.3555986138 0.1154859269 0.4396786997 0.2769792161
[1571] 1.0590006535 0.6445208159 0.3935288106 0.2421309855 0.5748147982
[1576] 0.0166118943 0.5284268550 0.2478831885 0.4587384126 0.8674437631
[1581] 0.6091219201 0.1431121087 0.2962249169 0.0965901175 0.4946614106
[1586] 0.0570715162 0.4233701132 0.3353662237 0.5723965253 1.9575627725
[1591] 1.4655610533 0.0325453484 0.3704211601 0.2336541383 2.6448535635
[1596] 0.4123828821 0.3964307730 0.3597708883 1.0802284778 0.8618800813
[1601] 1.2621684481 0.0596127366 0.0476440443 0.4741221118 0.2573985893
[1606] 0.2437552543 1.0802908526 0.2989190898 0.0111924487 0.2698937783
[1611] 1.0611577159 1.5734056798 0.3882767066 0.7184410432 0.4715978972
[1616] 0.1178879299 0.4334677348 0.3761410447 0.4791724075 0.7836958812
[1621] 0.7424232498 0.5704587573 0.1546278792 1.3427527013 0.9509949463
[1626] 0.9142021566 1.7835396625 0.3845924681 0.3495861713 0.3696559310
[1631] 1.3543779204 1.5192282217 0.7584610422 1.0059716119 0.6343479374
[1636] 0.3651748464 0.3213508829 0.3339205450 0.8259485020 0.1547961646
[1641] 1.1277484595 0.1188662771 0.5144448369 0.8879532234 1.1533562985
[1646] 0.3482671281 1.9066527528 0.8669162984 0.7302195659 0.1606553278
[1651] 0.0496966209 0.0987923619 1.1810541160 0.0660108460 0.2182857013
[1656] 0.5529085307 0.2845170429 0.4391838341 0.0650544122 0.6149392011
[1661] 1.1827822342 1.2227256406 0.0856454089 0.7364235286 1.2764041891
[1666] 1.1462894377 1.5942760858 0.4520093902 0.5946905678 0.4377566066
[1671] 1.3273857133 0.1356189621 0.0236982310 1.3329931283 0.4751146907
[1676] 1.5640197411 0.6715041631 0.0105116260 0.0325234680 0.5405581525
[1681] 0.1428745533 0.1985947647 0.2799815365 0.2190203741 0.3954902073
[1686] 1.3604482803 0.0421579166 0.4682668945 0.4612217902 0.4084819785
[1691] 0.0060769720 0.0518896674 0.7598296725 0.6758349305 0.3089977505
[1696] 0.8179284350 0.1544369342 0.6064305577 0.6446898814 0.8210228972
[1701] 0.4228365824 3.0123598913 0.3993683214 1.2885115157 0.3055103222
[1706] 0.0440996516 0.2965921927 0.0727558610 0.1063092898 0.9431055527
[1711] 0.0341992313 0.0628750057 0.7944716908 0.6751309969 0.0105796668
[1716] 0.6797944506 0.6325542936 0.6322519532 0.2446703553 0.0519779359
[1721] 1.2892291808 0.4938768013 1.0784456379 0.3514674264 0.3401247011
[1726] 0.5493217455 0.1680059316 0.2419192917 0.2788656640 0.1350594732
[1731] 1.1102571996 0.5476642487 0.3631740228 0.0448357356 0.9085468635
[1736] 0.1216582126 0.4989996652 0.4925978899 0.6466559678 0.6283550119
[1741] 0.3941020422 0.5556490550 0.1978740419 0.0573720481 0.0246558563
[1746] 0.2802240651 0.0753324104 0.0114781064 0.4403312176 0.5912517304
[1751] 0.0803141481 0.5943674380 1.1303522998 0.7054677626 0.2672062973
[1756] 1.3975345553 0.0743804287 0.5125730646 0.3727551481 0.3918926009
[1761] 0.8760408280 0.4978964914 1.3280349130 0.6434892686 0.4518486251
[1766] 0.4390755642 0.1162883137 1.0564354382 1.7396473664 2.0068074677
[1771] 1.6723159710 1.0394087596 0.4027722642 0.3219096660 0.1191817277
[1776] 0.0196481317 0.2734223533 0.0577227537 0.0145095430 0.2374914682
[1781] 0.2134201956 0.0209160462 0.0442109349 1.5156215954 0.2043843566
[1786] 1.0889947097 0.9928120335 1.0151431733 0.4437707569 0.4360214539
[1791] 0.4436360140 1.4497306123 0.5345116141 0.6471880785 0.1591033252
[1796] 0.2292782457 0.4970728711 2.6956611518 0.6164981646 0.1248534568
[1801] 0.5789630779 0.1129418424 0.7017650697 2.6434957368 0.3096079573
[1806] 0.0600358797 1.3005315175 0.5218988464 0.3041874268 0.4571332158
[1811] 0.6098826938 0.6023178327 1.1703716481 0.2619598091 1.3784905891
[1816] 0.4847484037 0.4850692195 0.2293175040 1.0581727357 0.1873638782
[1821] 0.5060450606 0.3721816558 1.0606096993 0.8080631000 0.5593186377
[1826] 0.4966912550 0.1033858685 1.6360843567 0.0704131847 0.1998671540
[1831] 0.2970630094 1.3197976242 0.3849415057 0.4236682789 0.3263005662
[1836] 0.9528238816 0.2234761809 1.0669925665 1.1632971610 0.6881532595
[1841] 1.3154478025 0.0305058803 0.3390899996 0.9580382210 0.9383272139
[1846] 0.1484149947 0.3775635936 1.7357174680 2.5861197767 1.6442329472
[1851] 0.0487099878 0.0767505525 0.6862770294 0.6305117432 0.0207326331
[1856] 0.4244118812 0.0341495859 0.6006353681 2.6145434653 0.4275383092
[1861] 0.1367065588 0.1482801467 0.0898157319 0.2614076684 0.3173273301
[1866] 1.5813078414 0.6810936219 0.4723161037 0.3682763158 0.4471870231
[1871] 0.4372241490 0.6763288784 0.1984649352 0.9065321987 0.0256305229
[1876] 1.1590818148 0.8297009666 0.9427714787 0.2808065636 0.3079631098
[1881] 1.3571915030 0.7500115966 0.5601445944 0.2186633579 0.3699753083
[1886] 0.9803800269 0.2191611140 0.4481260726 0.1250017423 0.1983360490
[1891] 0.2272846012 0.4577867619 0.6678579193 0.0145554265 0.2481894476
[1896] 0.7944417285 1.0403840877 0.4483413993 0.0768561887 0.6943895023
[1901] 2.3102415496 1.6006352509 0.1526584403 0.0293881913 0.2240743881
[1906] 1.5981933325 0.3127515368 0.0894864195 0.3645943642 0.2924651789
[1911] 0.2231446650 0.2821327450 0.2906401377 1.8068338361 0.4302737214
[1916] 0.3079213375 0.2045939152 0.6028993308 0.1453015106 0.9806752829
[1921] 0.6465710210 0.2490450462 0.6994388092 0.5449100071 0.4762100047
[1926] 0.0460088046 0.0200811232 0.2574335916 1.3394764515 0.3596022844
[1931] 0.1360319849 0.0631615071 0.2348559328 0.2310383371 1.9881419960
[1936] 0.2842764664 1.0246518906 0.3683755809 0.9978271828 0.2108568091
[1941] 0.8463743632 0.6219411267 0.1645802952 0.4270642117 0.1144005331
[1946] 0.2305187521 1.4193567490 1.3811604095 0.1374358896 0.5506244854
[1951] 0.1536404179 0.2776089996 0.2795711342 0.5090876789 0.1360420905
[1956] 0.2774982542 0.0678512420 0.4580536540 0.8101521000 0.1904407039
[1961] 1.5960478957 0.0832611825 0.0064784432 0.0679374414 1.4766782916
[1966] 0.1523323531 0.2471974515 0.4273256425 0.9965212220 1.1729823564
[1971] 0.5266558157 0.1663188634 0.3573235729 0.3087994876 0.4230364616
[1976] 1.6346349916 0.6653394833 0.9066320567 0.7348820381 0.4838656745
[1981] 0.8550985833 0.4356792180 0.5716954271 0.0717965844 1.3049073482
[1986] 0.0628017409 0.0477508513 0.2204097844 1.5266574167 0.2030270823
[1991] 0.0439933713 0.1699492548 0.3838737236 2.5762019882 0.9604296749
[1996] 0.7541305100 0.0692050538 0.3780686017 0.3174192330 0.1231529782
[2001] 0.1508992661 1.2611720377 0.2351870195 0.2923716733 0.6605127791
[2006] 0.1652059401 1.0683899416 0.8063425643 0.2486655898 0.2311438715
[2011] 0.7839049182 0.2522323291 0.5123281772 0.7116042644 0.0327845820
[2016] 1.5794290043 0.4347481095 0.2484052721 0.6499834422 0.8063661561
[2021] 0.6183100604 0.1047974404 0.0714400993 1.0069918181 0.3804437069
[2026] 0.2705413011 0.5390424550 0.9834651888 0.3082512729 0.6060731409
[2031] 0.1866880870 0.5685337653 0.6252467825 1.3638898970 0.5361310118
[2036] 0.6374886198 1.2328077097 0.2353683479 0.2286968646 0.1565836877
[2041] 0.0693376870 0.2122867461 1.1307096497 0.9878730235 0.0656407076
[2046] 0.9453531969 0.6990701287 0.6196736987 0.1848871525 0.2985723663
[2051] 0.9564147703 0.0547648317 0.2429320117 1.6917272635 0.5110345389
[2056] 0.7601422129 0.1014288213 0.1977138856 0.6037113419 0.3557818626
[2061] 0.2250493170 1.8703460414 0.5183962213 0.5110884974 0.1729481944
[2066] 0.3799073124 0.0047888251 0.2656771690 0.4867349869 0.1917548360
[2071] 2.3395611939 0.1346943887 0.0703924217 2.0162254156 0.1991838253
[2076] 1.0425328460 1.0209623087 0.7613132007 0.2960844284 0.8412580875
[2081] 0.3051501178 0.0418402127 0.1620712854 0.6270722271 1.4701056283
[2086] 1.0508505933 1.1227063839 0.1007732479 0.0320551610 0.2570175848
[2091] 0.1182433380 0.6029773065 0.5579172912 0.0884366808 0.7337454905
[2096] 1.2253782212 0.2867725993 0.1009599868 0.6826277707 0.1914822956
[2101] 0.1195423598 0.1498219424 0.3268510929 0.8467148314 1.5258671071
[2106] 0.1288551761 0.0614695448 1.3574362737 3.0138493123 1.1314346192
[2111] 1.0386316849 0.4388658124 0.0205134688 0.0711012464 1.0712599254
[2116] 0.9619622669 0.4263692723 1.0958311038 0.2112884318 0.5607986325
[2121] 0.0535660871 0.6697381465 0.6200920234 1.3504853297 1.4212680202
[2126] 0.0973189391 1.1925731973 0.4338096411 0.0229487455 0.6404784673
[2131] 0.8768583560 0.9617167519 0.2176371515 0.5896288448 0.4852322213
[2136] 0.6516628662 0.0394486575 2.3678492477 0.4110156748 0.4579609756
[2141] 0.0725120320 1.0498017127 1.7996397178 0.6770391902 0.4435795816
[2146] 0.3799532866 0.4527947574 1.1525256727 1.2245623174 0.1263235492
[2151] 0.2709476100 0.3332009822 1.2994650355 0.0103059914 0.9051086151
[2156] 0.5239085877 0.5965142585 0.0265386263 0.1610675697 0.1983801989
[2161] 0.2567020980 0.6601679142 0.1949428570 0.1349338069 0.6951163224
[2166] 0.3854606069 1.0398643188 0.7222993110 0.4064207399 1.8721129422
[2171] 2.2008674579 0.5334087580 0.6580791454 1.4503535172 0.2994114520
[2176] 0.3944651589 0.2872684218 0.6046356838 0.1478172944 0.2391134440
[2181] 0.9569946056 0.2057408803 0.5176439093 0.3327680231 0.3051659210
[2186] 0.3640203785 0.5602499597 1.7137133737 0.3107445677 0.0136756036
[2191] 0.0982026284 0.0651292766 0.4451482743 0.2734749812 0.3618807767
[2196] 0.4842722531 0.3880056046 0.0643737170 0.2551205199 0.2264147521
[2201] 0.0640909391 1.0383774824 0.0365719257 0.7349780520 0.6383088232
[2206] 0.6433660574 1.7613381622 0.0101145030 0.4368364619 0.7340447360
[2211] 0.2285475836 0.2299693853 0.8405722068 0.5411237005 1.4949959524
[2216] 0.4782779734 0.5265229613 0.6844744454 0.4405039348 3.0994071101
[2221] 0.5061935897 0.7677409961 1.3330714248 0.4859619293 1.7886352390
[2226] 0.2317160355 0.3486588399 0.7783330455 0.1879251080 1.7684929207
[2231] 0.9627521289 1.0322875346 0.9984357202 1.5018838989 0.3817680488
[2236] 0.1212771748 1.3122700373 0.5094617551 0.3380679063 0.4799490179
[2241] 0.3942423429 0.3743131889 0.2696954654 0.5968261599 0.9680124244
[2246] 0.3637230973 0.0236536646 0.7818155135 0.1404419542 0.6945538864
[2251] 0.3587873432 0.1362231534 0.6018001871 0.9392430480 0.4103879583
[2256] 0.4891639139 0.3671476392 0.0191879944 1.0300941882 0.1782251366
[2261] 0.0056675700 0.3574584023 0.0418667805 0.2975064883 0.3105584130
[2266] 0.0990512539 1.3118414470 0.6015858867 1.4267095206 0.7002605085
[2271] 1.7132376732 0.1363497802 0.4307722311 0.1384277329 0.9622859744
[2276] 0.1627400822 0.3220107863 1.5942016902 0.0946757558 0.1856997568
[2281] 0.4442253086 0.1666032661 0.3043437769 1.2712992239 0.3470114322
[2286] 0.3087039556 0.8629291632 0.2827742861 0.6023216833 0.5022332489
[2291] 0.7870778429 0.1630309331 0.0491735076 0.1906856072 0.2570332486
[2296] 0.2722011612 1.1853948541 0.7849957559 1.0375558620 0.8649339938
[2301] 0.1573826868 0.2298165848 0.2295790604 0.0411162364 0.1230628623
[2306] 0.0292022482 2.4828581598 2.1205500813 0.8285866371 0.2477190420
[2311] 0.5557642729 0.1312273395 0.6302715853 0.4412046421 0.5142518125
[2316] 0.2822598332 0.0957842749 0.1419146732 0.5758188545 0.4147608989
[2321] 0.5161497239 0.2621179423 0.1528454966 0.4150776995 0.1442850922
[2326] 0.1137835402 2.2684278804 1.8513385525 0.1262830514 0.4902510835
[2331] 0.1237526301 0.2407988201 0.5149467322 0.0152127719 0.3283165690
[2336] 0.3123483308 0.4982205557 0.9795762233 1.5737941081 0.0645345908
[2341] 0.0476098556 0.6892521839 0.7086624672 0.2245558822 0.2411822197
[2346] 0.2722492807 1.6295435826 0.2862724909 0.8656445745 0.7407463598
[2351] 0.1945165496 0.0383274447 1.3679847063 0.2534662912 0.0311757605
[2356] 0.5584170281 0.9011683195 0.0709982536 0.2101151544 0.0973866028
[2361] 0.8198030596 1.1610017948 1.1259904796 0.9745953408 0.6702742890
[2366] 0.0999980493 0.7507105721 1.1534229023 2.9006001932 0.2132930684
[2371] 0.5735682386 0.1222996182 0.1140655513 0.0225078559 0.5570027784
[2376] 0.5864176907 0.4812658297 0.2287088495 0.0707693886 1.0960926459
[2381] 0.8039979777 1.0209826765 0.4376675427 0.3120867621 0.7470944673
[2386] 0.7237596412 0.5302494401 0.2008674509 0.3922970151 0.2883952526
[2391] 0.8572437044 0.6297402784 0.1186235032 0.2767300691 0.1776747481
[2396] 0.6103093963 0.1701849354 0.4657406294 0.4817068226 1.0887671317
[2401] 1.2366417749 0.4161712490 2.4079660928 0.0369749924 0.0070633016
[2406] 0.5318756803 0.6153927751 0.4129411557 0.7154482839 0.5005037754
[2411] 1.8439161966 0.3744514441 0.7703151819 0.2193529291 0.3195065819
[2416] 0.1414696201 0.4896899413 0.2476823536 0.1180911180 0.0025215127
[2421] 0.1545132600 0.2246107577 1.1055946666 0.0470717441 0.8001469169
[2426] 0.3252860262 0.4026497036 1.5267983248 0.3785012360 0.5864778804
[2431] 0.8611800301 1.0183529494 0.0900959188 0.0318930198 0.0567129707
[2436] 0.4710414927 0.1295644467 1.3483266530 0.7211980528 0.2986416855
[2441] 1.1982829444 0.1969822924 0.8717486953 0.0922842307 0.5143360676
[2446] 0.9429227918 0.4423494731 0.0136266401 0.1494841653 0.3803613339
[2451] 0.6670790048 0.1726562387 0.8338255465 0.3617022035 0.5740802672
[2456] 0.0827966052 1.7532376025 0.2132394133 1.6155749693 0.9307828302
[2461] 0.6296080411 0.5285670954 0.8044851387 0.1858941271 0.4227178060
[2466] 0.3382449230 0.9667866174 0.7496435882 0.8285375707 1.9943903493
[2471] 0.3245230769 0.0708427019 0.7541084791 0.0559536417 0.6150360478
[2476] 1.1295623976 0.2858748617 0.1516734329 0.0326541019 1.0277073940
[2481] 0.2654277980 0.8162518847 0.5136419242 0.3084320644 0.0227316655
[2486] 1.0522455642 0.7013117911 0.1036752074 0.1863250517 0.2185232713
[2491] 0.6746986437 0.3256767636 0.8400978856 0.0181026175 0.0726844867
[2496] 0.1453027390 0.6600763262 0.4003733312 1.0146435078 0.5331605568
[2501] 0.3565604733 0.4663681897 0.9356401927 0.6665213921 0.5638776255
[2506] 0.0242895446 0.0883629607 1.5508162821 0.0452426652 0.4705708784
[2511] 0.0548908339 0.5885120882 0.2282446422 0.4171424961 0.5341346099
[2516] 0.4072801969 1.4708892673 0.4300026236 1.1481866460 0.1009199077
[2521] 1.3116477229 0.6524484221 0.8685118772 0.1821280931 0.4378786813
[2526] 2.2257467618 0.7359671094 0.3856888656 0.3656436647 2.0727781759
[2531] 0.2064984292 1.0228299711 0.3527970570 0.7322948468 0.3380950871
[2536] 1.2203595509 0.0182246193 0.6095145070 0.0538619958 0.4371891415
[2541] 0.1345998249 0.2710697412 1.3530618304 0.7896444906 0.0076131545
[2546] 1.1274048471 0.1457137174 0.7232663290 0.3439598310 0.1211896092
[2551] 0.3389706085 0.4094291426 0.2535278347 0.1677613891 1.5506455131
[2556] 0.6514515606 0.2722070148 0.3500932870 0.1789063463 1.3140677425
[2561] 0.4238867104 0.9014330918 0.0758455098 0.3335308339 0.0252618694
[2566] 0.1421170377 0.1841897652 0.1163715685 0.0050283858 0.8430343775
[2571] 0.2606161341 0.5230244648 1.4800989461 0.0363430936 0.0456381299
[2576] 0.3340272539 1.5072855621 3.1220306857 0.1624318505 0.6547053450
[2581] 0.4505242271 0.1049712891 0.2929751471 0.9306508796 0.2316284689
[2586] 1.3304981442 0.0758117691 0.1987642697 0.0305299506 0.3741193901
[2591] 0.0855525866 0.3745469530 0.0646774035 0.0064984224 0.7265746357
[2596] 0.6403683292 0.3733927802 0.5103264444 0.2358777676 0.5260760211
[2601] 1.3335399295 0.2319455067 0.4211095007 0.1245615987 0.3204967132
[2606] 0.1496024238 0.0711702277 0.0647894966 0.4535046368 0.1314393111
[2611] 0.0251508884 0.0313889392 0.1947808785 1.1432064478 0.9793202457
[2616] 0.3110249571 1.6158236992 0.8371443551 0.4127162992 0.4555788437
[2621] 0.6494551622 0.4162410399 0.2623232654 0.3412739664 0.1398912892
[2626] 0.6210937979 0.5298186930 0.4122217549 0.6345543032 1.1767428119
[2631] 0.0793415291 0.0591423828 0.4726760532 0.2450258773 0.4462380618
[2636] 1.6887415089 1.6000066638 0.6970830752 0.7996663505 0.9258158908
[2641] 0.1167366887 0.4415640451 0.1141934953 0.2625703407 0.3430868931
[2646] 1.3394905530 0.1188359105 0.7051454300 0.3369058260 0.3075675691
[2651] 0.6258426310 0.3378811695 0.2002214364 0.1470823779 0.5668090290
[2656] 0.4185913252 0.4917454066 1.1604726532 0.2974594529 0.1888306091
[2661] 0.6193381532 0.0554637643 0.4699023617 0.6105927646 0.9039212788
[2666] 0.0110199354 0.5027406148 0.5198692650 0.7984459280 0.0143881144
[2671] 0.9010122886 0.3829095527 0.3469548512 0.3488456526 1.4938150127
[2676] 0.7180990063 0.7754991043 1.3457704290 1.3221909178 0.2420572170
[2681] 0.1168479166 0.6811310262 0.6491468995 1.5644561516 0.1265656931
[2686] 0.3560690702 0.2812396023 0.8921024364 0.2470333124 0.1033807066
[2691] 0.0006043133 0.9654273621 3.1382595810 0.2987636230 0.3653358862
[2696] 0.2628324285 0.1099119811 1.2003226221 0.0812994492 0.0103980255
[2701] 0.2228877560 0.8708968021 0.0125995555 0.1679332761 0.1869011898
[2706] 0.3841234773 0.2863457207 0.7610280723 1.0525918948 0.9988060976
[2711] 0.9416541061 1.0894906591 0.1363635226 0.1397611069 0.2004783113
[2716] 1.1402657497 0.8711732368 0.5243286577 1.0292664090 0.4475005866
[2721] 1.0622709409 0.7462527923 0.8524433438 0.1698466771 0.4604934859
[2726] 0.0476532939 0.6186105760 0.1992663971 0.1771309504 0.2820174751
[2731] 0.4052127551 0.1703757792 2.6307375351 0.4050223181 3.2743956300
[2736] 0.5481810748 0.0894228040 0.3562208659 1.1864748376 0.2716435264
[2741] 1.1600987321 0.3964021701 1.0691189380 0.1854039517 1.0749000250
[2746] 0.3851615259 0.4426864775 0.2951527314 0.1282391820 0.0362470772
[2751] 0.4417662422 0.0636679700 0.9126616213 0.8619692249 0.3002958710
[2756] 1.9375357051 0.1043226123 0.7596192448 0.0106573814 0.0383340702
[2761] 0.4177192802 1.1859233709 0.2229027761 0.5537448097 0.0621264416
[2766] 0.2363328614 0.2761146227 0.3966886970 1.1102639261 0.0783880515
[2771] 0.2481457312 0.5561960976 0.3706733810 1.0659326597 0.3597733260
[2776] 1.0813222890 0.3192838925 0.9769103928 0.5614058923 0.5453308131
[2781] 0.1559938394 0.1330519555 0.4303953409 0.3385417757 0.0973877016
[2786] 0.7979334694 0.3362258634 0.9635842815 0.3699590313 0.2098121022
[2791] 0.3757339968 0.1974822744 0.7612251365 0.0941398818 0.1103957468
[2796] 0.1911727895 0.3659542846 0.1515952495 0.1460004617 0.6606947115
[2801] 0.1411433667 0.3581701128 0.2731316918 0.4716344080 0.5579547497
[2806] 0.0218098307 0.5627706239 1.5466771078 0.9204470979 0.5033025228
[2811] 0.5507132101 0.2665778331 0.9604707175 0.3418720003 0.7548966694
[2816] 0.3264790489 0.2759363244 1.0483931331 0.6512710414 0.6427136359
[2821] 0.3840345735 0.1370179058 1.0560696752 0.5914798289 0.2733854650
[2826] 1.0797609942 0.4962315916 0.0753514939 1.9429280735 0.1529657694
[2831] 0.9578040413 0.4144838978 0.9592314976 0.2687073025 0.0870495105
[2836] 0.1688248629 1.1236758310 0.2498402859 1.1514249927 0.3935565752
[2841] 0.2966867951 0.0284041078 0.6563804337 0.1891868189 0.1419489057
[2846] 0.3367920127 1.1879144320 0.0912208914 0.0705666683 0.3192924179
[2851] 0.0396935775 0.4105898892 0.0673435434 0.1640695775 0.2323917624
[2856] 0.1630060485 0.1830224225 4.1833075930 0.1054662778 0.5341211128
[2861] 0.3371187815 1.3779166130 0.2808664369 0.2566363137 1.1773916069
[2866] 0.4339842381 0.0620087867 0.5382882718 0.6225930875 0.4410298208
[2871] 0.5866087819 0.3512114826 0.1768444899 0.1394270224 0.3855965231
[2876] 0.1300101547 0.4607481922 0.1068467491 0.3299533085 0.1842162587
[2881] 0.9336646461 0.0162602640 0.7172527067 1.2060063809 0.1914397532
[2886] 1.4119409811 1.5833729293 1.7667757211 0.8551813282 0.1026373411
[2891] 0.2731679785 0.5315444363 0.1901593228 0.2495158189 0.7850497247
[2896] 0.2049029531 0.2720843801 0.2503533429 0.1005516195 0.7584793396
[2901] 0.3248662910 1.8491077439 0.0509332611 0.3454881038 1.5794288593
[2906] 0.9774558375 0.1096202328 0.3238160883 0.6213027685 0.1140253950
[2911] 1.3637497496 0.5490450174 0.7948184794 1.5189465604 0.3687621343
[2916] 0.8804748968 2.3638134356 0.2093094903 0.2720315069 0.0937660854
[2921] 0.0437611430 0.3830093549 0.1190520698 0.3636622856 0.8546989890
[2926] 1.5023158287 0.4814186856 0.0816195737 0.6340363057 0.1941013134
[2931] 0.3809154151 0.1627882974 0.1251424128 0.2432183737 0.6908527435
[2936] 0.5886374961 0.5270340659 1.2728100645 0.1460194527 0.2112876769
[2941] 0.1451462344 0.2248956025 0.3167477337 0.3966360777 0.0633130425
[2946] 0.2131746634 0.3009067407 0.1975244565 0.4788066465 0.2241680442
[2951] 0.4435423952 0.9128400138 1.9787263853 0.6225766508 0.7303574669
[2956] 1.0993649610 0.1180671340 0.1330780928 0.3173567732 0.1460798939
[2961] 0.0811705134 0.5538963292 1.4950487740 0.4537265473 0.2489740154
[2966] 0.6639588772 1.5096434004 0.2413224571 1.2772649570 0.6109590945
[2971] 0.9686568898 0.2481889648 0.1950255171 1.8638509769 0.7257885968
[2976] 0.5739413551 1.5805005583 0.9636866106 0.0537086908 0.6102279126
[2981] 0.3613921312 0.0219424873 0.1272145745 1.6372213994 0.1041292139
[2986] 0.6782989735 0.0582091575 0.3831714985 0.2527136808 0.1187326100
[2991] 0.1582022985 0.6385708589 0.1945754058 1.2423499550 0.8130853759
[2996] 0.4896668538 0.6112329053 0.9773733207 0.5752970431 0.1461288501
[3001] 0.2100800906 0.1104214799 0.8856313869 0.2036460858 0.3869494075
[3006] 0.3806137576 0.9963837119 0.4532513394 1.7122423312 1.0126485248
[3011] 0.0441158220 0.2337548362 0.3199887340 0.0359899085 0.0921357102
[3016] 0.3093479973 0.0136505152 0.1038079726 1.0740552612 0.7510014793
[3021] 0.6728410771 0.7920121838 0.1703376772 0.1683645504 0.8200378602
[3026] 1.9792214765 0.1821516459 0.1675377378 0.6969505573 1.0701378495
[3031] 0.4600345592 1.1508998846 0.1301679698 0.6700846663 0.7273108628
[3036] 0.1078566676 0.4826262821 0.8678730473 0.1719498222 0.7592809986
[3041] 0.8199064909 0.2135766067 0.7422246167 0.3077849207 0.5854517320
[3046] 1.5487391139 0.5222980630 0.0936558553 0.1693912507 1.3755271082
[3051] 0.5491415762 0.2494202684 0.2492895774 0.4893569129 0.5650180100
[3056] 0.0400540839 1.2910564640 0.7067899167 0.3727393910 0.2695445800
[3061] 0.2561331800 0.0584821865 0.8797420357 0.3923139192 0.3838340022
[3066] 0.8163660427 0.8311486734 1.5681957378 0.3487739300 0.3108079165
[3071] 0.6925927138 0.7448465275 0.2126160011 0.1834838972 1.0449087844
[3076] 0.7494238644 0.1846156705 0.8775607081 0.5326196804 1.2899092691
[3081] 0.4291898986 0.2066727875 0.3817218257 0.3599988466 0.1304807899
[3086] 0.0953287176 0.1904708193 0.1120669463 1.6471988858 0.4904310228
[3091] 0.0275961821 0.3551554790 0.2309748427 2.7313702728 0.5374157338
[3096] 0.6287767551 0.9201139025 0.1892352105 0.3098662482 0.2329670308
[3101] 0.3732973217 0.6972953959 0.1921851559 0.1249460938 0.0031894178
[3106] 0.5417545747 2.7439950525 2.9721510243 2.3054002259 2.0800856256
[3111] 0.1193551818 0.1613225945 0.0709216923 0.3098563180 0.3842156385
[3116] 0.5387511704 0.1899138854 0.0330923510 1.4097274683 0.0321902526
[3121] 0.2916722615 0.4588112406 0.4143529317 0.5014504864 0.0659842695
[3126] 0.4962259921 0.1619363050 0.1906868302 1.5930424955 0.3261287239
[3131] 0.0332184436 0.0496800292 0.2250988293 0.3548986385 0.4307512343
[3136] 0.3480977704 0.5169305955 0.3819959141 0.4673964209 0.3428450553
[3141] 0.2760209348 0.2616941636 0.3684968572 0.0869530796 0.4540771643
[3146] 0.6149016696 0.9340593349 0.7259667598 0.1053487970 1.3215030852
[3151] 0.9700007508 0.5658304557 1.1986858614 0.0918763402 0.0259534220
[3156] 0.0946984908 0.6897634212 1.1376147436 0.1231332393 1.2886381752
[3161] 1.0626820288 0.1562504288 0.6178900715 0.3232125960 0.0299273996
[3166] 1.1762397507 0.4581353588 1.8799608091 0.1376467078 1.9249315735
[3171] 0.2253372762 0.3323411576 1.1491416946 0.0306824676 0.8969042946
[3176] 0.2856726814 0.1854349619 0.7702468809 0.2847473072 0.2982814373
[3181] 0.1145172723 0.5934217234 0.0038648785 0.9456162580 0.0601776474
[3186] 0.0424936057 1.5123518091 0.3397701659 0.0475705529 0.2466043063
[3191] 0.0392264167 0.5066628087 0.6397041308 0.2579566043 0.2054927299
[3196] 0.0517891860 0.1912129981 0.2208987620 0.4717821017 0.6757553331
[3201] 0.1037379257 0.5674507783 0.0538162479 0.4156793767 0.5291821543
[3206] 0.2618607505 0.6848672481 1.5384719154 0.0779004371 0.6895198897
[3211] 0.5139317970 0.7014584876 0.0830983370 0.8967189692 0.1089983100
[3216] 0.5513674640 2.0260185163 0.9434550559 0.6378867946 0.3211836386
[3221] 0.4209894352 0.0577014027 0.3902417979 0.4113185731 0.0889913924
[3226] 0.1644375539 0.9195481597 0.1959917194 0.3072014911 0.6880813836
[3231] 0.4715424025 0.8208335989 0.1657616048 0.1830376318 0.8889980846
[3236] 1.5293082131 0.9423445351 1.2269859497 0.4709515767 0.7060878510
[3241] 0.6322491478 0.6334830160 0.0175310330 0.7601603750 0.5349537103
[3246] 0.4954358280 0.0014104384 0.0974428150 0.3522540242 2.0030018432
[3251] 0.1932264613 0.2972847251 1.0440005271 0.0245098280 2.2241325840
[3256] 0.2830228052 0.4141178091 0.1819096659 0.3922732274 0.1067284155
[3261] 0.7738306014 2.3054228706 0.0858781743 0.0989061756 2.5275972523
[3266] 0.7500490988 0.0387858918 0.2772995863 0.3124897474 0.0420184780
[3271] 0.3735223372 0.6691625373 1.0414368237 0.6910868588 0.3108380903
[3276] 0.0990713527 0.2409690657 0.6995974284quantile(x = New_RNA_PRO_DF$delta_logFC , 0.95) 95%
1.837277 hist(New_RNA_PRO_DF$delta_logFC, breaks = 20)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
New_RNA_PRO_DF <- New_RNA_PRO_DF %>% mutate(Upper_quant = New_RNA_PRO_DF$delta_logFC > quantile(x = New_RNA_PRO_DF$delta_logFC , 0.95))
New_RNA_PRO_DF uniprotswissprot hgnc_symbol RNA_LogFC RNA_Pval Pro_LogFC
1 Q15327 ANKRD1 0.5423696485 3.495016e-01 -3.5538167761
2 O76021 RSL1D1 -0.3165324128 9.036930e-02 -2.1410928975
3 Q96LW7 CARD19 -0.3762588406 1.269744e-01 -1.6342957224
4 Q969Q1 TRIM63 -0.6881603653 1.389441e-01 -4.3423803749
5 P19388 POLR2E 0.1833535360 1.788005e-01 -1.1658966201
6 O43159 RRP8 0.0018779486 9.922191e-01 -2.1096892264
7 Q6EMK4 VASN -1.0133534707 2.813836e-02 2.3724491682
8 P17844 DDX5 -0.7407595340 7.355961e-06 -1.1425406345
9 Q96PU8 QKI 0.8749065610 8.348710e-04 -2.1455298252
10 Q14498 RBM39 0.2549266523 2.249342e-01 -0.8019789647
11 P67809 YBX1 -0.5089170511 3.434736e-03 -1.1045436713
12 Q9BQG0 MYBBP1A 0.5716789901 4.860616e-02 -2.2554253126
13 P17480 UBTF -0.2859211398 2.180101e-01 0.7861550384
14 Q13641 TPBG -1.2104107982 2.462399e-03 1.3614453777
15 P48634 PRRC2A 0.7258176554 6.107409e-05 -1.0858313049
16 Q92841 DDX17 1.0249205760 1.803967e-05 -0.7539368895
17 Q4G0J3 LARP7 0.2871172108 2.958777e-01 -0.7752299178
18 P78347 GTF2I 0.1886927212 1.309096e-01 -0.7435322555
19 Q02818 NUCB1 0.2009846164 3.514145e-01 -2.3955560537
20 Q00341 HDLBP 0.1728733945 4.730758e-01 -0.9058215272
21 Q13123 IK -0.0645533917 6.866371e-01 -1.1338838135
22 Q92522 H1-10 0.5329391054 8.572555e-03 -1.6536207267
23 Q14980 NUMA1 0.2147599937 3.527295e-01 -1.2192370415
24 Q14694 USP10 0.5831468596 8.741223e-08 -0.7674689571
25 Q2TAY7 SMU1 -0.2784190109 5.782096e-03 -0.7632109180
26 Q9NR30 DDX21 0.1249955267 6.201663e-01 -1.0206069551
27 O60427 FADS1 -0.1040094213 5.328441e-01 -1.2083869980
28 Q9P258 RCC2 -1.0866075184 4.199620e-04 1.7059490390
29 Q9Y6M5 SLC30A1 -1.8426913753 5.128952e-11 1.1382005458
30 Q9BVP2 GNL3 0.5743682342 5.357130e-04 -1.5081799250
31 Q9P0V3 SH3BP4 0.0942406107 7.300890e-01 -1.5653815562
32 Q6P5R6 RPL22L1 2.1440916090 3.626716e-06 -1.8797159229
33 Q92934 BAD 0.6354167891 1.824699e-02 -1.2351650877
34 Q86XP3 DDX42 -0.1455115793 3.521690e-01 -0.7285835498
35 O95864 FADS2 1.8763059331 2.691634e-08 -2.6174073619
36 Q9NZB2 FAM120A 1.2006566587 6.991516e-09 -1.0158315089
37 Q9UQE7 SMC3 0.5524711623 9.667542e-04 -1.4794349461
38 Q6P1J9 CDC73 0.3520036546 9.455214e-02 -0.7979336434
39 P16989 YBX3 -2.1656880461 3.985001e-14 -2.7782295557
40 Q9BZK7 TBL1XR1 0.1495431334 5.563774e-01 -0.6448869669
41 P08865 RPSA 0.0537509777 8.534899e-01 -0.6951266140
42 P26640 VARS1 0.2861313217 8.598609e-02 0.5742911993
43 Q96T58 SPEN -0.1889594124 4.670353e-01 1.2393881736
44 Q13151 HNRNPA0 0.2808603380 6.222551e-02 -0.7134418171
45 Q9Y2X3 NOP58 0.1478492848 2.800142e-01 0.6514755296
46 Q13451 FKBP5 -1.1939860867 1.003869e-03 0.7026843452
47 Q9UKA9 PTBP2 0.5104961052 6.227976e-02 -0.7576536433
48 P23434 GCSH 0.3253055817 2.167016e-01 0.9639278116
49 Q9Y333 LSM2 0.4165739498 9.885059e-02 -1.6242843304
50 Q53EP0 FNDC3B -0.3467806595 2.628028e-01 -1.4507298032
51 P62906 RPL10A 0.1085318331 6.383740e-01 -0.9477995132
52 P49711 CTCF -0.3667183065 2.640275e-02 -0.7460068993
53 P42285 MTREX 0.3220399833 4.353403e-02 -0.9617635928
54 Q16718 NDUFA5 0.3375636380 3.512106e-01 -0.6128746798
55 P62854 RPS26 -0.0594327323 8.141256e-01 -1.7373368214
56 Q9BQ39 DDX50 -0.6460429567 1.338170e-03 -1.1157407297
57 P62750 RPL23A -0.5370063453 1.083308e-03 -1.1141546927
58 Q9H2P0 ADNP 0.5623371965 3.959623e-05 -1.0743673769
59 Q49A26 GLYR1 -0.1064954776 4.887237e-01 0.8520902429
60 Q9UQB8 BAIAP2 -1.6114954212 1.724253e-04 1.1594641852
61 Q96L96 ALPK3 -0.0192366895 9.552033e-01 -1.7454620125
62 P62753 RPS6 0.2998923006 1.630510e-01 -0.6301099885
63 P16403 H1-2 -2.0059097186 5.623946e-11 -1.5769850831
64 P62273 RPS29 -0.3122428969 2.583113e-01 -0.7268629014
65 Q99536 VAT1 0.3685522223 2.869995e-01 0.7708229050
66 Q06136 KDSR -1.5154715177 1.182475e-08 0.7405558040
67 Q9UQ35 SRRM2 0.0665815693 8.060578e-01 -0.5903700138
68 Q96RU2 USP28 1.1205263279 1.247180e-06 -0.8072247663
69 P61254 RPL26 -0.1634115532 5.189082e-01 -0.8148623788
70 Q14728 MFSD10 0.2303285416 3.155888e-01 0.7768860215
71 Q9H1E3 NUCKS1 -0.2524100387 9.341759e-02 0.9093433795
72 Q86U42 PABPN1 -0.1201465652 5.446108e-01 -0.6371784527
73 P61313 RPL15 -0.2777577556 6.150198e-02 -0.5116069160
74 Q01780 EXOSC10 0.6078974986 5.992892e-06 -1.8332257421
75 P46782 RPS5 0.1669044709 4.352819e-01 -0.7266249638
76 Q9HCM4 EPB41L5 -0.3657468712 1.615621e-01 0.8163123746
77 P30876 POLR2B -0.4105165460 5.497988e-03 -1.0153940278
78 P39880 CUX1 0.2712355427 1.232083e-01 -0.6669134126
79 Q9NQT5 EXOSC3 -0.0591001711 7.319892e-01 -0.9054903012
80 P62280 RPS11 -0.0437036854 8.521183e-01 -0.6059548196
81 P62701 RPS4X -0.1338643168 7.047699e-01 -0.5729549732
82 Q92747 ARPC1A 0.2732384855 5.453804e-02 0.6126517330
83 P36578 RPL4 0.2460868547 1.199925e-01 -0.4568522015
84 P62888 RPL30 -0.0155926213 9.563555e-01 -0.6160229343
85 Q5QJ74 TBCEL -1.4662009183 5.426043e-12 -1.1986896135
86 O75787 ATP6AP2 -0.6821280852 1.086495e-01 1.6934062614
87 P49207 RPL34 -0.1211116692 6.382085e-01 -0.9596894143
88 Q9P0M6 MACROH2A2 0.4935875694 3.905499e-07 1.6001832065
89 Q6Y7W6 GIGYF2 -0.1024997998 5.643843e-01 -0.9044508349
90 Q7Z739 YTHDF3 -0.5222794108 3.378136e-04 -0.7250445918
91 Q8NC51 SERBP1 0.2679755058 7.545723e-02 -0.8540143136
92 P18621 RPL17 -0.5348164756 6.742014e-03 -0.6967076722
93 O00461 GOLIM4 -0.1540253416 6.585118e-01 -0.4757964569
94 P46783 RPS10 -0.5896367473 1.341147e-02 -0.9888508824
95 P19338 NCL -0.3814844249 5.133478e-02 -0.5172166796
96 P53396 ACLY -1.2193091206 6.052200e-03 1.0062251308
97 Q99459 CDC5L 0.2154638895 8.196734e-02 -0.6906765081
98 Q9Y5S2 CDC42BPB -0.2852836767 1.334011e-01 -0.5251120289
99 Q9Y2I6 NINL 0.2586382080 2.314292e-01 0.5208548082
100 O60292 SIPA1L3 0.0896779474 6.332390e-01 1.2411170961
101 P61513 RPL37A 0.1556896334 5.251190e-01 -0.5882082097
102 Q13509 TUBB3 -1.2463074828 4.480636e-02 0.7849629140
103 Q9NVP1 DDX18 0.2250775953 7.684463e-02 -0.6777723393
104 P62263 RPS14 0.1186696646 6.268403e-01 -0.6026084568
105 P16220 CREB1 0.1002609718 4.352588e-01 -0.5031254586
106 Q9UKU7 ACAD8 0.1364006897 3.756701e-01 0.5589429736
107 P34932 HSPA4 -0.6130166200 8.478545e-05 0.5788276899
108 P83731 RPL24 0.0199956587 9.315324e-01 -0.5543597613
109 P62249 RPS16 0.2841806551 2.946914e-01 -0.6667823795
110 P25398 RPS12 -0.3797426277 1.522246e-01 -0.5878505606
111 Q12983 BNIP3 0.5236624690 5.832608e-01 -1.1241955717
112 P07996 THBS1 0.9957149963 1.485370e-01 -1.6006476533
113 Q14966 ZNF638 0.0470025052 8.313867e-01 -0.7779107967
114 P17302 GJA1 1.0024333545 6.579793e-03 -1.1116578520
115 Q9UBG0 MRC2 -0.0485667744 9.275443e-01 -1.0789245230
116 P55769 SNU13 0.4032101161 3.799754e-02 0.5414058709
117 P21453 S1PR1 1.4274102716 2.512511e-07 -1.0074850656
118 P15529 CD46 -1.4098171521 4.689571e-07 0.5800084020
119 P83881 RPL36A 0.4502476157 9.321517e-02 -0.7844961130
120 Q06830 PRDX1 -0.9340143668 5.122866e-02 0.5174185908
121 Q9NUP9 LIN7C -0.3853882539 1.204831e-01 -0.6427814586
122 P08708 RPS17 -0.1856452739 4.429504e-01 -0.8002218256
123 P62269 RPS18 0.1069074033 6.059797e-01 -1.0084011844
124 O00541 PES1 -0.0638765453 7.365412e-01 -2.3190460799
125 P62910 RPL32 -0.0787556324 7.508022e-01 -0.7025333738
126 P50914 RPL14 0.1960652298 2.503990e-01 -0.4629932812
127 Q9NYV4 CDK12 0.3764525948 3.462818e-02 -0.6501491349
128 P61353 RPL27 -0.1297737964 5.862650e-01 -0.4807151241
129 P54764 EPHA4 -0.3959965658 9.940504e-02 1.3983624382
130 P62841 RPS15 -0.4927651457 7.587736e-03 -0.6722019865
131 P61247 RPS3A -0.4367032139 5.334327e-02 -0.5803803999
132 P62857 RPS28 -0.2735144838 6.438816e-01 -1.3991428488
133 P29558 RBMS1 -0.3008464951 3.105908e-02 -0.4794151940
134 Q99873 PRMT1 -0.0670870432 6.567542e-01 0.4642899702
135 P62424 RPL7A 0.0448473591 7.268621e-01 -0.5670129678
136 P18077 RPL35A 0.1172737360 6.081130e-01 -0.5872810025
137 Q9H307 PNN 0.4950469311 7.883106e-03 -0.7368335650
138 P06748 NPM1 0.0629947752 8.012141e-01 -0.6721264871
139 Q8IWC1 MAP7D3 0.2931146269 2.701569e-01 -0.7035432539
140 Q9NPL8 TIMMDC1 -0.3458313149 1.145294e-02 -0.5256142728
141 Q92784 DPF3 1.4622008139 2.254046e-09 -0.9494860176
142 Q9H2K0 MTIF3 -0.0604631902 7.829920e-01 -1.4597652645
143 O00571 DDX3X -0.5880584735 2.960967e-03 -0.5290939081
144 Q9BYV2 TRIM54 1.4386359326 1.550574e-02 -1.0838816024
145 P46778 RPL21 0.1378669900 5.816250e-01 -0.4880244806
146 Q9GZS1 POLR1E 1.1068653352 1.334246e-06 -0.8329828638
147 P19320 VCAM1 5.7863632154 1.134608e-08 -2.4632413096
148 P05387 RPLP2 -0.1553830106 4.149530e-01 -1.0476033013
149 P32969 RPL9 -0.3735452234 2.068902e-01 -0.4397303828
150 P82979 SARNP 0.3174775373 6.651951e-02 -0.6838448301
151 P60510 PPP4C -0.1236748345 4.315664e-01 -0.4109111435
152 Q71RC2 LARP4 -0.2273063245 1.410006e-01 -1.3241873915
153 Q13084 MRPL28 0.8271051167 3.084432e-05 -0.9432339010
154 Q6P5Q4 LMOD2 3.2175509094 5.842445e-05 -1.1211381976
155 O43660 PLRG1 0.1472372167 2.847966e-01 -0.5044680663
156 Q9H832 UBE2Z -0.7181425114 6.721573e-05 0.7271212659
157 P62851 RPS25 0.0062667403 9.805571e-01 -1.6985247921
158 P62847 RPS24 -0.5096428043 4.835569e-03 -0.5606924342
159 Q9BYN8 MRPS26 0.4978233367 1.287251e-02 -1.2591913827
160 Q9Y3Y2 CHTOP 0.2899907269 2.274058e-02 -1.3635409111
161 P11940 PABPC1 -0.3428583069 1.658003e-01 -0.4467117211
162 Q9H0S4 DDX47 0.1751222851 3.151134e-01 -1.4130213235
163 P62899 RPL31 -0.0598351306 8.425184e-01 -0.4297886272
164 Q16658 FSCN1 -0.9495832435 9.367219e-03 0.5376047849
165 Q9BXB1 LGR4 1.2805016735 5.359533e-08 -1.6471304981
166 Q13310 PABPC4 0.4333442177 1.219707e-04 -0.4220855821
167 Q68CP9 ARID2 0.6805067410 9.729348e-06 -0.5392572756
168 Q9NR56 MBNL1 0.6315622690 4.800199e-03 -1.6782527965
169 Q5BKY1 LRRC10 3.8479511258 1.373363e-08 -1.0063252056
170 O75155 CAND2 1.6911947908 1.475912e-05 -0.8070167308
171 Q12972 PPP1R8 0.1028381590 4.506624e-01 -1.2890200440
172 P62917 RPL8 0.1874298912 3.737473e-01 -0.4759712554
173 Q15758 SLC1A5 -0.7960474559 5.215009e-02 1.6055961679
174 Q9UJV9 DDX41 -0.0650175184 8.471726e-01 -0.8936118551
175 Q9H0A0 NAT10 0.5836673271 1.051245e-03 -0.8083854490
176 Q9H7H0 METTL17 0.3284008459 9.959660e-02 -0.4444226909
177 Q9Y3U8 RPL36 -0.0784290817 6.804384e-01 -1.0547820892
178 P39019 RPS19 -0.9358010869 2.615819e-06 -0.9746307783
179 P63244 RACK1 0.4945450512 3.137162e-03 -0.4428959494
180 Q12888 TP53BP1 0.7963358058 6.702687e-06 -0.5710654747
181 Q15024 EXOSC7 0.2756435422 2.117596e-01 -0.4925725531
182 P25101 EDNRA 1.1591768528 2.582678e-06 -0.4080247904
183 Q9P013 CWC15 -0.2977485608 7.896910e-02 -1.0350132316
184 Q9UNK0 STX8 1.0851469606 5.055426e-06 -0.5908648570
185 P46781 RPS9 0.1185755912 6.772641e-01 -0.5203788401
186 P98155 VLDLR 0.5641684176 3.781976e-03 -0.7958276532
187 P46776 RPL27A -0.1238618382 4.572328e-01 -0.7746361337
188 Q9NY33 DPP3 -0.0230043562 9.467111e-01 0.7104695951
189 Q9BR76 CORO1B -0.7955866668 2.205256e-03 0.5548415064
190 Q99766 DMAC2L 0.1745906472 5.356163e-01 -0.5964048840
191 Q9BQ95 ECSIT 0.6228001120 2.220967e-02 0.6415744071
192 P29401 TKT -1.6166951239 3.333491e-03 0.5151478042
193 P78396 CCNA1 -3.7597154042 3.862465e-06 -0.5207857144
194 Q9Y224 RTRAF -0.1404486080 4.739177e-01 -1.4394805400
195 P51970 NDUFA8 0.9532891926 1.007481e-03 -0.4287029276
196 Q969Q0 RPL36AL -0.0013377286 9.941708e-01 -2.5438450163
197 Q11201 ST3GAL1 -0.3704414676 1.070530e-01 -1.1179694119
198 O96013 PAK4 1.3294755471 2.005242e-09 -0.7887611969
199 Q14444 CAPRIN1 0.3399395502 1.224001e-03 -0.5416817723
200 Q13283 G3BP1 0.1174380221 4.352588e-01 -0.6991609801
201 P23396 RPS3 -0.0244107222 8.976225e-01 -0.4169526676
202 Q92520 FAM3C -0.5180705970 5.693321e-02 -0.7789476428
203 P62244 RPS15A 0.1542285851 5.678381e-01 -0.4298640795
204 P19474 TRIM21 -0.8505053089 8.767955e-04 -0.7914407893
205 P47914 RPL29 0.0097464034 9.678269e-01 -0.8915834740
206 P60866 RPS20 -0.6384526455 1.886575e-03 -0.4642474623
207 Q14839 CHD4 0.7313790878 1.083429e-05 -0.3899063239
208 Q8WUT4 LRRN4 1.1156621206 6.247524e-02 -1.7898291377
209 O75940 SMNDC1 0.0792686064 6.234391e-01 -0.9057750747
210 Q8WVM0 TFB1M 0.9067679530 1.948248e-04 -0.7050242947
211 O95433 AHSA1 0.0768270140 6.250759e-01 0.6888824932
212 Q9GZQ8 MAP1LC3B -1.2290243216 1.126835e-06 0.4997938598
213 Q8IY95 TMEM192 -0.4205827416 1.125052e-01 -0.4084318083
214 P39023 RPL3 0.3080976843 6.405062e-02 -0.4153614928
215 O43148 RNMT 0.2066377958 1.687837e-01 -0.4156445083
216 P36873 PPP1CC 0.6351661722 4.864267e-05 -0.4399589985
217 Q16555 DPYSL2 2.1706762391 1.215465e-05 0.6223084191
218 Q9UNE7 STUB1 -0.0810940217 6.652149e-01 -0.6951469188
219 Q00839 HNRNPU -0.1628177675 2.933821e-01 -0.3563229842
220 Q9UJA3 MCM8 1.6219135563 4.286690e-08 -0.4142764701
221 P04066 FUCA1 -2.1028351663 1.343373e-06 0.4469205277
222 Q13586 STIM1 -1.4102797908 8.097095e-09 0.6298863463
223 Q9P032 NDUFAF4 0.4899183878 1.103590e-01 -0.5274168749
224 Q8N3V7 SYNPO -0.9532842945 1.069135e-01 -0.7572117675
225 P02462 COL4A1 0.0703481228 8.636317e-01 -0.7414080073
226 P28799 GRN -0.4950963009 1.613259e-02 0.5931696188
227 P26373 RPL13 0.1074644094 6.335468e-01 -0.5645815732
228 P78540 ARG2 -0.0767858913 9.095050e-01 -0.5239525168
229 P27635 RPL10 0.0554514130 8.188589e-01 -0.4730751821
230 O00303 EIF3F 0.2080701424 1.182386e-01 -0.4014406815
231 P48740 MASP1 0.1574737844 7.328062e-01 -0.8551857038
232 P50895 BCAM 0.3644328300 5.301379e-01 0.3371940543
233 Q9NY27 PPP4R2 -0.0160083908 9.188219e-01 -1.0496574340
234 P15880 RPS2 -0.1256455183 5.971345e-01 -0.4052133229
235 Q8WWM7 ATXN2L -0.0787973165 6.906027e-01 -0.4028447239
236 P62266 RPS23 -0.0013911916 9.951722e-01 -0.5503947248
237 P42766 RPL35 0.0457884393 8.780237e-01 -1.3454650365
238 P78346 RPP30 0.4830240047 4.405524e-03 -0.7178325605
239 Q8TB96 ITFG1 -0.2981325990 1.560165e-01 0.8584113427
240 Q9H2W6 MRPL46 0.2279096678 4.035797e-01 -0.8109774106
241 Q16851 UGP2 0.0029359651 9.902724e-01 0.4303957377
242 Q96HP4 OXNAD1 0.5731209896 1.325697e-02 -0.3870496758
243 O14735 CDIPT -0.8058775904 3.844745e-07 0.6227885873
244 P08758 ANXA5 -0.8925552947 9.041284e-03 0.6197817327
245 Q9NYY8 FASTKD2 0.9049356525 1.243965e-04 -0.5852458646
246 P46779 RPL28 -0.2034809793 2.585471e-01 -0.3987696346
247 Q9Y3D9 MRPS23 -0.0568288787 8.301168e-01 -0.6067669038
248 P54819 AK2 0.3648377403 1.990512e-02 -0.4920832708
249 Q9Y3T9 NOC2L -0.4889902843 5.286748e-05 -1.6245155473
250 P30050 RPL12 -0.3102467457 2.019839e-01 -0.4647297615
251 Q5RKV6 EXOSC6 0.4047865698 1.017811e-01 -1.3849747643
252 O95104 SCAF4 -0.3301704317 7.597994e-02 -0.9055782502
253 Q13045 FLII 0.2513858624 1.021944e-01 -0.3767310091
254 Q9UEU0 VTI1B 0.2642975454 1.130288e-01 -0.8768551571
255 Q9H0D6 XRN2 -0.1837978535 1.756149e-01 -0.4686270379
256 Q9P0M9 MRPL27 0.0593475532 8.539815e-01 -0.6511987136
257 O60828 PQBP1 0.4900046328 7.052813e-05 -0.8124911955
258 Q5VT52 RPRD2 0.4550760007 5.273264e-02 -1.0233266627
259 P82932 MRPS6 -1.4505446953 5.540140e-06 -0.4358097247
260 O60832 DKC1 0.6947629385 6.973185e-05 0.4659275185
261 Q15061 WDR43 -0.7812836834 1.716509e-06 1.1347468039
262 Q5T481 RBM20 0.8819416375 2.811629e-04 -0.4517640243
263 Q9H511 KLHL31 2.2783900339 2.371431e-05 -1.3304992746
264 Q9HD26 GOPC 0.0008763120 9.958031e-01 -1.2928101198
265 Q13885 TUBB2A 0.0597056068 9.023055e-01 0.4790130748
266 Q9BYD3 MRPL4 0.8362775985 7.678685e-05 -0.6339303010
267 Q02543 RPL18A -0.2891848150 1.617336e-01 -0.3894487283
268 Q9UBE0 SAE1 0.8181978469 5.830672e-07 -0.7810261501
269 P62316 SNRPD2 0.3020759116 2.086768e-01 -0.4206857485
270 P52907 CAPZA1 -0.2164052920 2.503990e-01 0.3113855959
271 Q9Y676 MRPS18B 0.7233214718 2.558969e-04 -0.6528927231
272 P01130 LDLR 0.1198290011 7.939456e-01 -2.5854233520
273 P62633 CNBP 0.3989750262 3.906168e-02 -0.8721945896
274 Q9Y6M9 NDUFB9 0.3237702457 2.458497e-01 -0.6729555239
275 P28370 SMARCA1 0.4981713943 9.046414e-03 -0.6445959769
276 P62913 RPL11 0.0216580344 9.178005e-01 -0.3456255710
277 P20908 COL5A1 0.0077279234 9.902724e-01 -0.9037705832
278 Q9Y4D1 DAAM1 -0.1254258437 4.109070e-01 -0.4805785925
279 P13805 TNNT1 1.0068783914 2.636288e-03 -0.9512257565
280 P62241 RPS8 -0.1587323616 3.394358e-01 -0.4539554775
281 O15270 SPTLC2 0.7253863974 2.553260e-03 -0.8836958713
282 Q5SY16 NOL9 0.1816399045 2.563003e-01 0.7251262997
283 Q9NZJ7 MTCH1 -0.2938380442 4.532038e-02 0.3461815482
284 Q96SI9 STRBP -0.1609476687 2.137362e-01 -1.2108323950
285 Q96GC5 MRPL48 -0.1443070528 5.111842e-01 -0.3919758789
286 P26641 EEF1G -0.0689973087 7.246135e-01 0.3608725244
287 Q96E52 OMA1 0.8801346479 3.115714e-04 -0.5609662542
288 Q96A72 MAGOHB 0.9207700009 1.230800e-04 -1.5596755214
289 P06396 GSN -0.1817545324 6.809838e-01 0.5182610885
290 P62745 RHOB -0.3920291281 1.600153e-01 -0.6805853306
291 Q8WVV9 HNRNPLL -0.6536880337 1.409387e-03 -1.7099407745
292 Q99496 RNF2 0.1769816439 3.544101e-01 -0.3722565806
293 Q12974 PTP4A2 -0.1225014446 4.621706e-01 -0.5389948290
294 Q6PKG0 LARP1 0.2805042938 8.462617e-02 -0.7611523705
295 Q9BRQ6 CHCHD6 1.6230743804 8.745341e-09 -0.6735268248
296 P31483 TIA1 0.2743497218 2.502705e-01 -0.5595298142
297 Q14137 BOP1 0.6993891592 8.666290e-06 -1.0527081619
298 O75427 LRCH4 0.6380826733 4.480257e-07 -0.8247443289
299 Q5T8D3 ACBD5 0.1846336387 2.135512e-01 -0.4910145082
300 O75822 EIF3J 0.0944707624 5.053986e-01 -1.1509904452
301 P51116 FXR2 -0.0514965589 7.173752e-01 -0.3192980472
302 Q92797 SYMPK -0.4353086253 7.972376e-04 0.4093278008
303 P36405 ARL3 0.2263495682 2.345075e-01 0.9012283787
304 P12277 CKB 0.0802026196 7.857749e-01 0.4928765668
305 Q96C36 PYCR2 -0.2511283080 4.619373e-02 0.4938772506
306 Q9HCD6 TANC2 0.6996840112 4.362276e-02 -0.8589839307
307 Q9Y2R9 MRPS7 0.1842542118 3.419440e-01 -0.7858436518
308 Q9HAT2 SIAE -0.1645405316 4.858789e-01 0.3056520776
309 Q9P2F8 SIPA1L2 0.1373712624 6.224173e-01 -0.6524360656
310 Q68E01 INTS3 0.5155336479 2.088983e-03 -0.9403976021
311 Q16850 CYP51A1 0.8873943450 3.428984e-04 -0.5381837521
312 Q14789 GOLGB1 0.0869764249 6.403854e-01 -0.4014819772
313 Q5T8P6 RBM26 0.1168519656 3.847801e-01 -0.7024127638
314 Q9BTD8 RBM42 -0.2342168959 4.429647e-01 -0.7436159729
315 Q92900 UPF1 -0.5270460842 1.085298e-02 -0.3735692039
316 P68032 ACTC1 2.1954078615 9.556916e-06 0.3587171349
317 O14949 UQCRQ -0.2261677317 5.375570e-01 -0.4731493370
318 Q9P2D3 HEATR5B -0.2164620244 2.458497e-01 0.8062594119
319 P07437 TUBB 2.4539199959 1.346482e-12 0.3844328233
320 P43155 CRAT -0.5402284509 1.146006e-02 0.3269702218
321 Q92945 KHSRP -0.1528435146 2.703341e-01 -0.3122001624
322 O60264 SMARCA5 0.5166142102 1.285809e-05 -0.3950351402
323 Q969V5 MUL1 0.2728545634 4.831754e-02 -0.8109338807
324 P46063 RECQL 0.1223529613 7.581931e-01 0.5941972155
325 P13987 CD59 -1.0162186604 2.461916e-04 0.4092945541
326 P84090 ERH 0.1966450727 1.644475e-01 -0.6396746570
327 Q71U36 TUBA1A 1.4021216608 1.098121e-05 0.4290536337
328 Q9BUF5 TUBB6 -0.7276692060 2.668735e-03 0.4609134230
329 Q5VZP5 STYXL2 1.2515035896 2.189358e-02 -0.5405508547
330 P80303 NUCB2 0.4203168918 2.927701e-02 -1.2165969840
331 Q92667 AKAP1 0.9545320217 1.026714e-05 -0.8204931203
332 P63220 RPS21 -0.0191404628 9.547250e-01 -0.9255878960
333 Q96JC1 VPS39 -0.4699787619 3.935340e-04 0.6779912933
334 P46976 GYG1 0.0078442435 9.814166e-01 0.6244557293
335 P63272 SUPT4H1 -0.5384631514 1.016012e-05 -0.9228884654
336 P62195 PSMC5 -0.0087478083 9.536399e-01 0.4573170199
337 Q08289 CACNB2 1.0870390762 2.312329e-03 -0.4092162305
338 P35556 FBN2 0.7100883122 2.330280e-02 -0.5225697573
339 P54709 ATP1B3 -0.3089159007 3.849201e-01 0.3512522227
340 O14979 HNRNPDL 1.0306517805 5.107003e-07 -0.2924607292
341 O60341 KDM1A 0.0872847729 5.153440e-01 -0.3443014115
342 Q15181 PPA1 0.4079346900 2.491160e-01 0.9516982601
343 Q96AE4 FUBP1 0.9363571166 5.536343e-08 -0.3770316600
344 Q8WZA1 POMGNT1 -0.0109817447 9.529130e-01 -0.5457677543
345 Q9NRX2 MRPL17 0.8605785394 3.140535e-05 -1.0740722708
346 P55042 RRAD 0.7688042127 1.231594e-01 -0.4036987232
347 P18124 RPL7 -0.1367387601 5.732436e-01 -0.3741115347
348 O75367 MACROH2A1 -0.4465099799 1.059118e-03 0.3524598606
349 Q8WX93 PALLD 0.4014122865 2.124664e-02 -0.5543441210
350 Q07960 ARHGAP1 0.9021028730 1.856772e-04 0.2922541606
351 P40429 RPL13A -0.2035821453 2.615269e-01 -0.3283224071
352 P52701 MSH6 1.0272848441 9.966054e-06 0.7948613613
353 P30566 ADSL 0.2364629204 4.556902e-02 0.5548074412
354 P46100 ATRX -0.0195891859 9.214757e-01 0.4591933947
355 P55789 GFER 0.1714220170 3.846111e-01 -1.4332328192
356 P41229 KDM5C -0.1194961205 7.352198e-01 1.6930720368
357 Q4U2R6 MRPL51 -0.1438654574 4.516234e-01 -0.8497542868
358 Q9Y520 PRRC2C 0.0744350860 6.724141e-01 -0.4122738367
359 Q13868 EXOSC2 0.9940876365 1.113388e-07 -0.6709261237
360 O60504 SORBS3 1.3006950994 1.021733e-07 -0.4752360642
361 Q01668 CACNA1D 0.3771640882 3.578012e-01 0.4155162081
362 Q14195 DPYSL3 0.8827320969 3.411693e-03 0.3862646005
363 P29218 IMPA1 -0.3686568123 8.875258e-02 0.5414487333
364 Q13416 ORC2 0.6384997150 4.257490e-04 -0.6343380016
365 P63208 SKP1 -0.3882136335 2.127564e-02 -0.5720193097
366 O60749 SNX2 -0.5193840648 9.628923e-04 0.4210399720
367 P60520 GABARAPL2 -0.5980287446 2.891437e-03 0.3000299316
368 P27105 STOM -1.2455487476 3.287804e-07 -0.4290548550
369 Q2M3C7 SPHKAP 3.1667088674 1.529116e-03 -0.8221551990
370 P28838 LAP3 -0.3104866216 5.130279e-02 0.3032390802
371 Q13098 GPS1 -0.0450396127 7.334863e-01 -0.6335783250
372 Q14165 MLEC -0.6798477294 2.428190e-03 0.3464119029
373 Q8TAQ2 SMARCC2 0.2258610407 1.727956e-01 -0.3737634055
374 P51784 USP11 -0.6450091305 3.606982e-03 0.8161837895
375 Q96KR1 ZFR 0.1049359300 6.498938e-01 -0.3748355103
376 Q7Z2W9 MRPL21 0.4048853397 1.310670e-01 -0.6916203087
377 P56385 ATP5ME 0.0232226747 9.522307e-01 -1.0637270214
378 Q9Y5B9 SUPT16H 0.2030047055 2.310478e-01 0.2954668383
379 Q9NVM9 INTS13 0.3988358940 9.932321e-04 -1.3026924690
380 Q92598 HSPH1 -0.7613134255 1.436923e-04 0.3804315943
381 Q9BT78 COPS4 -0.0195633515 9.370910e-01 -1.0558452099
382 P37108 SRP14 0.2726095961 4.252475e-01 -0.6169511964
383 P05204 HMGN2 -0.0788204280 7.571384e-01 -1.2085669392
384 O14656 TOR1A -0.8186753412 3.559545e-04 0.4511341811
385 Q3ZAQ7 VMA21 -0.4170151266 1.182572e-02 -0.4151625218
386 P13807 GYS1 -0.1264663904 7.073062e-01 0.4516558156
387 Q9P015 MRPL15 1.2789894244 1.319160e-04 -0.5904530367
388 Q15043 SLC39A14 1.5983854558 3.239786e-09 -0.7832229949
389 Q9Y5Q9 GTF3C3 0.4779158425 2.972656e-02 -1.0813404482
390 P17655 CAPN2 -0.0749915165 8.344448e-01 0.2934613225
391 P09661 SNRPA1 0.6417607018 9.520794e-03 -0.5332923877
392 Q16775 HAGH -0.1962403378 3.290442e-01 0.3476464592
393 Q9ULC3 RAB23 -0.0549202741 8.028234e-01 0.4260306931
394 Q96AA3 RFT1 0.3812161119 1.349483e-01 1.0958445515
395 Q9NQW7 XPNPEP1 0.2651260227 5.654978e-03 0.4582743679
396 Q07666 KHDRBS1 0.3353122796 2.495134e-03 -0.4688445046
397 Q13308 PTK7 0.0071098280 9.807059e-01 0.4373290166
398 P68104 EEF1A1 -0.2470038476 2.381038e-02 0.3181740149
399 Q9H6H4 REEP4 1.0575919641 1.259830e-03 0.4640746350
400 Q8N201 INTS1 -0.1771978166 2.839828e-01 -0.8975844927
401 P43007 SLC1A4 0.2281585816 5.039942e-01 1.8802482838
402 Q8TCC3 MRPL30 0.4680122762 2.163909e-03 -0.6584219344
403 Q8WV74 NUDT8 -0.9970464088 1.154943e-03 -0.5504330912
404 Q9NXV6 CDKN2AIP 0.1468676663 5.083058e-01 -0.4972596863
405 P12429 ANXA3 0.3652194368 1.433188e-01 0.3176720787
406 P23229 ITGA6 -0.6257620402 1.400451e-01 0.6595635443
407 Q9UP95 SLC12A4 -1.4325877990 5.177903e-07 -0.4635346249
408 Q9BXX0 EMILIN2 -0.0783713227 6.822287e-01 -0.6344854439
409 Q71UI9 H2AZ2 0.6135690089 2.147418e-04 -0.4301336551
410 Q9Y2W2 WBP11 0.8287414540 4.007254e-04 -0.4028048673
411 Q15637 SF1 1.2527316777 4.090712e-11 -0.4581816870
412 P84098 RPL19 -0.2385906121 9.704783e-02 -0.4721135303
413 Q96EL2 MRPS24 0.3574359187 3.768453e-01 -0.4131804042
414 Q14197 MRPL58 0.2719690900 2.256413e-01 -0.3695335464
415 Q9Y3Q4 HCN4 0.4662549138 6.640458e-02 -0.7093931841
416 Q08379 GOLGA2 0.8215388821 5.563077e-06 -0.4895793901
417 P51532 SMARCA4 0.5154207060 4.659437e-03 -0.3179279487
418 P13645 KRT10 0.4673739666 6.983123e-02 -2.0029629530
419 Q92905 COPS5 0.5404312642 4.092852e-03 0.4018375134
420 Q9NTI2 ATP8A2 -1.4022203539 5.365945e-03 0.4929770512
421 P55265 ADAR -0.1619696324 5.258018e-01 -0.6610507874
422 O00291 HIP1 0.9405567383 5.841820e-05 -0.3009509003
423 Q99613 EIF3C 0.3928267492 1.139536e-01 -0.3061523124
424 P85037 FOXK1 0.1520530566 4.664245e-01 -0.8461871169
425 Q96JJ7 TMX3 0.2736242923 3.247071e-01 0.3344933002
426 Q6IN84 MRM1 -0.3747478403 1.138166e-01 -0.6194351122
427 Q8N5M1 ATPAF2 -0.9191643340 1.050751e-08 0.8283158927
428 Q9ULA0 DNPEP 0.5047163836 4.193959e-02 0.3580605778
429 P62081 RPS7 0.0690921127 7.880325e-01 -0.3610348386
430 Q8IWS0 PHF6 0.4902379537 4.041485e-02 -0.6440290831
431 P15848 ARSB -0.4096872277 7.803900e-02 0.3891627085
432 Q9BQQ3 GORASP1 0.4132613005 5.365424e-04 -0.7132660761
433 P22087 FBL 0.8289703912 4.178859e-04 0.4594797427
434 Q12996 CSTF3 -0.6960501727 3.031616e-03 0.3031950790
435 P55884 EIF3B -0.4618877814 4.749722e-03 -0.3126922986
436 P07195 LDHB 0.2491087735 3.948683e-01 0.3203974681
437 Q9UN86 G3BP2 -0.7040184543 6.113209e-07 -0.2989675130
438 P23468 PTPRD 1.0787928665 9.758776e-04 -0.9630380004
439 P54920 NAPA -0.8502220740 1.077099e-08 -0.6048193942
440 P02452 COL1A1 0.6721815204 5.358371e-01 -0.8630373614
441 Q16531 DDB1 -0.3948834173 2.522025e-03 0.2763074102
442 P68371 TUBB4B 0.3006574067 1.056926e-01 0.3750467234
443 P49458 SRP9 0.2669696641 1.234128e-01 -1.0415756021
444 P56537 EIF6 -0.1902817074 1.307247e-01 0.6675807342
445 Q96B26 EXOSC8 2.0101417868 2.989705e-13 -0.6792508671
446 P68366 TUBA4A -1.4354288035 2.628266e-02 0.4272030385
447 P62277 RPS13 -0.2690662375 1.640769e-01 -0.3846046816
448 Q16822 PCK2 -0.1756835712 6.825087e-01 0.4709793965
449 Q5BKZ1 ZNF326 0.1951961438 3.308689e-01 -0.3647787281
450 Q13263 TRIM28 0.0962837324 5.528096e-01 -0.2937293605
451 Q9BVK6 TMED9 0.3155895074 3.025056e-01 0.4827264623
452 P23528 CFL1 -0.5758998949 3.722646e-03 0.3117478150
453 Q8IX01 SUGP2 -0.0137509656 9.191644e-01 -0.2795046931
454 Q9BY50 SEC11C -0.3268293953 3.941064e-01 -1.2684329185
455 Q16787 LAMA3 -0.6907573539 2.712123e-01 -0.3462892463
456 Q92743 HTRA1 0.2307052769 5.141306e-01 0.8623326478
457 O60506 SYNCRIP 0.1590813816 2.914142e-01 -0.3910241522
458 Q07020 RPL18 -0.0471146593 7.870350e-01 -0.2858289428
459 Q96QZ7 MAGI1 0.5570774145 2.358907e-04 -0.4339758253
460 P35637 FUS 0.3390490981 3.724655e-02 -0.2990647406
461 P09012 SNRPA 0.1910245206 2.180101e-01 -0.3090219578
462 Q9H1E5 TMX4 -1.4146185712 1.891611e-08 0.3043317235
463 O14776 TCERG1 0.7901206455 2.620191e-09 -0.3458759592
464 O96000 NDUFB10 1.0000141615 5.569011e-04 -0.4227285183
465 P60468 SEC61B -0.2153534445 4.482293e-01 -0.5599036128
466 P82914 MRPS15 0.0752106813 6.496023e-01 -0.8500467295
467 Q13247 SRSF6 0.5386303730 5.001146e-03 -0.2604375079
468 Q14152 EIF3A 0.1726139814 2.890248e-01 -0.3089986079
469 P56589 PEX3 0.6372032138 5.751769e-04 -0.9449411391
470 Q8TDN6 BRIX1 0.3654738576 5.006356e-02 -0.7560440425
471 Q96DB5 RMDN1 -0.1772339474 4.038820e-01 -0.4723676141
472 Q9Y3A3 MOB4 0.0255375791 9.528946e-01 -0.3440229284
473 Q92800 EZH1 -0.4801464253 1.969336e-02 0.3908564702
474 Q6PJT7 ZC3H14 0.4034031224 2.096873e-03 -0.4874957222
475 Q8IZV5 RDH10 -2.1353159089 2.660668e-13 1.1706138848
476 P04632 CAPNS1 0.2368317063 1.936450e-01 0.2772049278
477 Q9NR34 MAN1C1 0.4481741366 6.484816e-02 -0.9665615416
478 P19404 NDUFV2 0.6998375558 2.028573e-03 -0.3781730368
479 Q6NZY4 ZCCHC8 0.2875460765 1.407064e-01 -0.4962457368
480 P38919 EIF4A3 -0.5451352258 2.358548e-03 -0.3684189605
481 Q6PIU2 NCEH1 -1.3116846487 1.526136e-03 0.5851131103
482 Q29RF7 PDS5A 0.6470874046 1.134430e-06 -0.5547108799
483 Q13202 DUSP8 0.4228096168 3.353131e-01 1.8187243965
484 Q8IUH4 ZDHHC13 0.5036690751 2.816376e-02 -0.5153855648
485 P0DMV9 HSPA1B -0.8663812989 2.021490e-02 0.2708637003
486 P07305 H1-0 -1.2559973086 2.904490e-02 -1.0334128888
487 P50750 CDK9 -0.7910846063 2.340011e-07 0.2855567380
488 Q99653 CHP1 0.1309733547 2.945199e-01 -0.4448151817
489 Q99643 SDHC -0.0968659127 5.549480e-01 0.4862583138
490 P42677 RPS27 -0.6445649133 1.414077e-02 -0.3351396054
491 O95169 NDUFB8 0.0506719816 8.751558e-01 -0.4606033708
492 Q9HCD5 NCOA5 0.2887085858 1.446025e-01 -0.3506594591
493 P18583 SON -0.0818892058 5.755145e-01 -0.9153020232
494 Q00059 TFAM 0.2011667397 2.513114e-01 -0.7790856934
495 O95218 ZRANB2 -0.0456755950 7.610537e-01 0.3083065194
496 Q9Y2X7 GIT1 -1.4967307021 1.466811e-10 0.3132612547
497 Q96HD1 CRELD1 0.3642374314 6.328671e-02 0.2715033937
498 P78559 MAP1A 0.4226387467 2.747778e-01 0.3942175556
499 O43395 PRPF3 0.2201058117 3.849201e-01 -0.5403943652
500 Q13347 EIF3I -0.2477456755 8.042413e-02 -0.2716999379
501 Q86UU1 PHLDB1 -0.1668358344 5.754920e-01 0.2530908683
502 O76031 CLPX 0.0035449924 9.832379e-01 -0.3107116887
503 Q9NWB1 RBFOX1 1.1281874868 1.169248e-01 -0.9501738753
504 Q9H2G2 SLK 0.0526281272 8.608871e-01 0.3681217777
505 Q96QE5 TEFM -0.2918104476 2.138701e-01 -0.4496117216
506 P19429 TNNI3 2.3467024412 2.301703e-05 -0.9714665218
507 Q15366 PCBP2 0.0030323143 9.886746e-01 -0.3037069974
508 O75616 ERAL1 -0.3518307158 5.553771e-03 -0.9408901443
509 P61764 STXBP1 -0.3988562463 2.493912e-01 0.5756644880
510 Q12907 LMAN2 -0.3156453918 1.074554e-01 0.2621010721
511 Q8NBK3 SUMF1 0.2109373270 5.845005e-01 -0.4603575127
512 P20645 M6PR -0.4647944846 3.844957e-02 0.4711022282
513 Q9UBU9 NXF1 -0.6411723992 1.886110e-02 0.5022800746
514 P32119 PRDX2 0.0766155588 7.966408e-01 0.3696025245
515 P61201 COPS2 -0.2718669436 1.040782e-01 0.2930714596
516 O75431 MTX2 0.0322426388 9.018516e-01 -0.3629461236
517 Q8IWA5 SLC44A2 0.5717115459 7.597003e-02 0.3109732814
518 P24844 MYL9 0.2870405810 2.959670e-01 -0.5627771670
519 O43488 AKR7A2 -0.1358950402 4.967546e-01 0.4110057430
520 P17252 PRKCA 0.4593747770 1.034073e-01 0.2962363732
521 Q08945 SSRP1 1.0802132673 1.029047e-08 0.3710919668
522 P55061 TMBIM6 -0.0717644373 6.847280e-01 0.4929378830
523 P07099 EPHX1 -1.9148323190 1.510118e-07 0.3221245491
524 P49756 RBM25 0.1755407515 2.902732e-01 -0.5368877021
525 Q92643 PIGK 0.7292956331 2.254813e-03 0.4288792875
526 Q9HAN9 NMNAT1 -0.2910727001 1.152230e-01 0.3991490568
527 O15144 ARPC2 -0.6100720629 2.066893e-05 0.3211464316
528 P62979 RPS27A 0.0395205375 8.730709e-01 -0.2239699579
529 Q13642 FHL1 1.0965471675 3.659715e-02 0.3805890001
530 O75083 WDR1 -0.3374692161 1.847864e-01 0.2340067894
531 Q13547 HDAC1 0.8040082602 3.445784e-05 -1.0167907744
532 Q15365 PCBP1 0.0993692416 6.057608e-01 -0.3061675928
533 O75569 PRKRA -0.5328514505 1.381915e-02 0.3809017814
534 Q7LBC6 KDM3B 1.0176730569 2.037186e-08 -0.9503690547
535 Q8NCA5 FAM98A 1.1007004384 6.895728e-08 -0.2770389541
536 Q6P1L8 MRPL14 -0.0188183573 9.463694e-01 -0.3469523732
537 Q9P289 STK26 -0.0773877778 7.551357e-01 0.4756052660
538 P05388 RPLP0 -0.1908294607 3.397934e-01 -0.2717749456
539 P47985 UQCRFS1 -0.0457454155 8.623682e-01 0.2737215840
540 O75477 ERLIN1 0.9890699467 4.421037e-03 0.9477072136
541 Q03518 TAP1 -3.1736455781 1.479107e-08 0.4421568992
542 P61160 ACTR2 -0.2940751330 2.985995e-01 0.3580260837
543 P47756 CAPZB 0.2739979063 1.202877e-01 0.2822669904
544 P31937 HIBADH 0.6887903854 9.639952e-04 0.3441131027
545 O60716 CTNND1 0.4035269561 3.311900e-01 -0.2304867318
546 Q9H0U6 MRPL18 -0.5507188132 9.301754e-05 -1.3334459844
547 P36969 GPX4 -0.1335553661 5.274344e-01 0.2666889930
548 Q8WY22 BRI3BP 0.8292030105 4.240227e-02 0.4902556476
549 Q9H6U8 ALG9 -0.3675387700 4.968232e-03 0.9940491999
550 P62937 PPIA -0.9008668330 2.162977e-06 0.2950316011
551 Q9NPC6 MYOZ2 0.9109674806 1.246893e-02 -0.5035953865
552 E9PAV3 NACA 0.2581178070 2.269935e-01 -0.4199626116
553 P24539 ATP5PB 0.4977984458 3.617286e-02 -0.4602042411
554 P08670 VIM -1.1785896409 3.597197e-05 0.2688944771
555 Q15274 QPRT 0.5395076738 5.065405e-02 0.2424456522
556 Q9NUL7 DDX28 -0.5469654820 1.973327e-03 -0.9091187813
557 Q14240 EIF4A2 0.3995775654 1.659073e-02 -0.3120783275
558 Q8N2Q7 NLGN1 1.8778072491 5.407303e-09 -0.7657686906
559 P46821 MAP1B -0.1636857451 5.696421e-01 0.3085520521
560 Q9NVA2 SEPTIN11 -0.5036513202 2.945199e-01 0.4225280356
561 P05413 FABP3 1.2309485446 3.634266e-04 0.2972655757
562 O76062 TM7SF2 -0.5559958215 6.128040e-03 0.2490267354
563 Q9ULD2 MTUS1 -0.7096277477 5.396461e-02 -0.7733423209
564 Q9BTV4 TMEM43 0.1545802524 6.906027e-01 0.4077539594
565 P22314 UBA1 0.0636136551 6.862526e-01 0.2742359818
566 P49189 ALDH9A1 0.3314445510 1.113250e-01 0.2844682295
567 Q8WYA6 CTNNBL1 0.2123630545 1.096362e-01 -0.4901126467
568 P63027 VAMP2 0.0998023599 6.710640e-01 -0.6054917542
569 O00267 SUPT5H -0.2086574583 1.889684e-01 -0.4883081268
570 Q8NBJ5 COLGALT1 0.1146598393 7.352198e-01 0.3474954001
571 O14841 OPLAH 0.8163379560 1.409651e-03 -0.4760189497
572 P17600 SYN1 -0.1656643340 7.339746e-01 0.5994787416
573 Q9UKK9 NUDT5 -0.2026747363 2.779936e-01 0.3541283421
574 Q86XL3 ANKLE2 -0.1916505126 4.429647e-01 1.3845804736
575 P05198 EIF2S1 0.0973122814 3.981279e-01 -0.3544038723
576 P51688 SGSH -0.1004932999 7.268621e-01 0.2929826523
577 Q86UL8 MAGI2 0.4296374072 1.322177e-01 0.3862327095
578 P00367 GLUD1 -0.2893886116 1.301154e-01 0.2670106787
579 Q96BJ3 AIDA 0.1917527460 4.898020e-01 0.6582557815
580 Q99575 POP1 0.0956093303 7.534672e-01 -0.6414286222
581 O43719 HTATSF1 0.4384987692 5.781667e-03 0.3884105367
582 Q86X76 NIT1 -0.2862856475 8.634769e-02 0.3856365267
583 O95210 STBD1 -0.5584720177 4.751430e-02 0.2866070079
584 P42356 PI4KA -0.2367648935 1.029220e-01 1.2271614838
585 O43678 NDUFA2 -0.4041656581 1.833207e-01 -0.5458101749
586 P23246 SFPQ 0.6611575762 2.564757e-03 -0.2168170966
587 P19784 CSNK2A2 -0.1355469726 3.194378e-01 0.7709444858
588 P17096 HMGA1 -0.2357947196 4.906365e-01 -0.5797074831
589 Q9UKM9 RALY -0.0483677000 7.785561e-01 -0.4627118864
590 Q9H6W3 RIOX1 0.1292883279 3.904879e-01 -0.5569526335
591 P55786 NPEPPS -0.5797105043 1.268447e-04 0.3432192302
592 Q07812 BAX -0.6413241147 2.582908e-02 0.4538761304
593 P22234 PAICS 1.6520499009 3.041109e-09 0.3942821645
594 Q9NZ43 USE1 0.3351504929 8.915003e-02 -0.4723754360
595 Q9H3P7 ACBD3 -0.5997582631 2.242583e-05 -0.3259712832
596 Q8NFW8 CMAS 0.2392759251 1.849662e-01 0.2913882873
597 P15170 GSPT1 0.0415525754 7.839481e-01 0.4042387632
598 Q5VYK3 ECPAS 0.0108414164 9.417671e-01 0.4792864217
599 Q9UII2 ATP5IF1 -0.3284880457 2.263708e-01 -0.5779054981
600 O43708 GSTZ1 -0.7799865069 1.831524e-05 -0.6957611001
601 O75607 NPM3 1.5239330544 5.414239e-06 -0.9024633221
602 Q53FA7 TP53I3 -1.3570560321 3.446817e-04 0.5307514644
603 Q9NPH2 ISYNA1 -1.3444834440 1.362227e-08 0.4510412715
604 P07741 APRT -0.3832130302 6.588620e-02 0.4023932468
605 Q14257 RCN2 0.6425795337 7.231870e-02 -0.8584705001
606 Q14157 UBAP2L 0.1914422774 3.604566e-01 -0.3441134306
607 Q24JP5 TMEM132A 0.2414741743 6.313552e-01 -1.4422446639
608 Q01518 CAP1 -0.5346497883 2.751801e-01 0.3829117241
609 P61962 DCAF7 -0.4815590890 3.404176e-04 -0.3313386279
610 O15460 P4HA2 -0.9766244719 1.487283e-03 -0.3027177373
611 Q99747 NAPG -0.4343916927 1.543643e-03 -0.3890434609
612 Q8TAE8 GADD45GIP1 0.3882491564 1.062931e-01 -1.2300854866
613 P43490 NAMPT -1.0194115561 6.849385e-04 0.5174534867
614 Q7L2E3 DHX30 0.0340490413 8.159683e-01 -0.2764088254
615 O75695 RP2 -1.1714405268 8.368133e-03 0.4557587058
616 Q53R41 FASTKD1 1.3223735741 3.743997e-04 -0.3721521378
617 Q6IBS0 TWF2 -0.1173084348 7.841181e-01 0.7200825532
618 O94832 MYO1D 0.2690337919 6.476079e-01 0.7113059870
619 Q9BYC8 MRPL32 -0.4480979361 2.429880e-02 -0.2881419915
620 P48643 CCT5 -0.0058820803 9.772284e-01 0.2426027202
621 O15372 EIF3H -0.2610659080 3.763684e-02 -0.3263963987
622 Q96AQ6 PBXIP1 -0.0163638588 9.621687e-01 0.3309292514
623 Q7L5N1 COPS6 -0.2350807816 9.640492e-02 0.3315156795
624 Q9NVR2 INTS10 0.0338200374 8.453607e-01 -0.8769919926
625 Q9UMX0 UBQLN1 0.2922786773 1.457348e-03 -0.2377988557
626 Q9NQ50 MRPL40 0.6286217574 3.878009e-03 -0.3913373827
627 Q14683 SMC1A 0.4311916987 8.116395e-02 -0.5756236294
628 Q14232 EIF2B1 -0.6603408853 8.111896e-09 1.9462616239
629 Q92604 LPGAT1 0.7704135697 5.514489e-07 1.0405755950
630 P08572 COL4A2 0.4491763899 1.258861e-01 -0.3643688597
631 P07384 CAPN1 -1.3219536649 6.187266e-07 0.2261268785
632 P52272 HNRNPM 0.2186810007 1.847864e-01 -0.2797465658
633 Q86W42 THOC6 -0.4215140472 6.582871e-02 -0.9444680116
634 P28347 TEAD1 -0.0286435805 8.816473e-01 -0.3519508310
635 P50461 CSRP3 0.2294442348 6.251060e-01 0.2553134985
636 P00390 GSR -0.5967623594 1.877845e-04 0.2636667900
637 P46777 RPL5 0.0831884957 6.476079e-01 -0.2495164254
638 P04181 OAT -0.0401454901 9.416420e-01 0.9716895965
639 Q96DU9 PABPC5 0.8939401998 6.783585e-04 0.6708709984
640 P35241 RDX -0.1606314650 3.331075e-01 0.2499929201
641 P31943 HNRNPH1 0.4866003602 3.866085e-03 0.2549349323
642 Q5VTL8 PRPF38B 0.1010820245 5.542266e-01 -0.4484439926
643 P07737 PFN1 0.1190329014 6.606078e-01 0.2594450203
644 Q6IQ23 PLEKHA7 0.8724483086 7.178181e-03 -0.3220582211
645 P28289 TMOD1 1.0742952939 2.057250e-02 -0.3767097442
646 Q9UBQ5 EIF3K -0.0067538517 9.802232e-01 -0.3198561727
647 O15431 SLC31A1 1.2095187333 1.510118e-07 0.8765074048
648 Q93052 LPP 1.3285364435 1.294344e-09 0.5077176987
649 Q15233 NONO 0.6393183642 2.593862e-08 -0.2203773267
650 B0YJ81 HACD1 0.8508394849 1.807684e-03 0.4263671815
651 P00441 SOD1 -0.4671522469 7.872033e-03 0.4394854663
652 Q01085 TIAL1 -0.0550344146 6.381128e-01 -0.3549740982
653 Q2V2M9 FHOD3 1.2501354304 1.815337e-05 -0.7493233584
654 P49674 CSNK1E -0.1962455236 5.504317e-01 -0.7750987888
655 Q9NWH7 SPATA6 0.3844624298 1.008895e-01 0.5727472293
656 Q8IXM3 MRPL41 0.6549381927 6.640458e-02 -0.3990313451
657 Q9NX58 LYAR 0.5242236978 6.336421e-02 -0.8605130413
658 P43304 GPD2 0.0926100540 7.999934e-01 0.3402365495
659 P05556 ITGB1 -0.0767833405 7.007477e-01 0.2519834655
660 Q8NBN3 TMEM87A 0.2225276227 3.289896e-01 -0.4900780058
661 Q96CT7 CCDC124 0.1104749174 5.125304e-01 -0.4060190842
662 Q969Z0 TBRG4 0.2053348669 1.958325e-01 0.2455943690
663 Q08380 LGALS3BP 0.8116587964 8.347575e-03 -0.2613356849
664 Q96T23 RSF1 -0.3474590463 1.893405e-02 -0.3131375395
665 Q9Y3B8 REXO2 -0.9568243220 3.426112e-06 -0.4786573745
666 Q92575 UBXN4 0.2809817986 9.823708e-03 -0.2357279698
667 P27144 AK4 -0.5534132180 3.175948e-01 -0.6088953174
668 Q9BUE6 ISCA1 0.0163704418 9.340454e-01 -0.5666584588
669 Q9NRZ5 AGPAT4 1.2574505904 4.846370e-07 -0.4871600338
670 Q8N8S7 ENAH 0.1605520564 4.794633e-01 -0.5071440857
671 Q9Y4E8 USP15 -0.6910215805 3.446377e-04 0.4269619270
672 P22695 UQCRC2 0.1706856323 3.959487e-01 0.2418092957
673 Q8ND56 LSM14A 0.3059021188 2.680936e-02 -0.3500765191
674 Q8N1F8 STK11IP -0.3656655059 5.497988e-03 -0.6479501264
675 A1L0T0 ILVBL 1.5030893035 3.659487e-09 -0.2521369710
676 Q9UN36 NDRG2 0.1470911810 6.569264e-01 -0.4168096232
677 Q9BQT8 SLC25A21 1.4846188142 5.402980e-06 0.2914019843
678 Q12824 SMARCB1 0.0348891813 8.905595e-01 -0.3203859112
679 O94905 ERLIN2 0.1035191096 4.586469e-01 0.2275121181
680 Q9NRG9 AAAS 0.6726711025 2.071350e-05 -0.3584746085
681 O60237 PPP1R12B 1.7489695447 3.631344e-04 -0.4003948098
682 O15533 TAPBP -0.0792272891 7.451698e-01 0.4751868334
683 P51608 MECP2 0.0697471352 6.652472e-01 0.4218689960
684 P61158 ACTR3 0.0769307747 8.048556e-01 0.3166017563
685 Q03001 DST 0.6671658276 1.485206e-04 -0.6141941812
686 Q9BVT8 TMUB1 0.1919158489 3.566117e-01 -0.5405761239
687 P55809 OXCT1 -0.2174422855 1.693419e-01 0.2434337963
688 Q99832 CCT7 -0.1183479718 2.591770e-01 0.2478731192
689 Q9Y619 SLC25A15 -1.3600982211 6.843738e-10 0.4805033783
690 O14910 LIN7A -0.0029448527 9.940050e-01 -0.3979042815
691 Q9P2D7 DNAH1 0.0317203002 9.247605e-01 -0.3617650877
692 P45974 USP5 0.4272082820 3.347588e-04 0.4780870272
693 Q9Y6R4 MAP3K4 0.1365172003 3.829033e-01 -0.3299816274
694 Q9BRA2 TXNDC17 0.0869574681 7.454704e-01 0.5433263672
695 P39748 FEN1 0.7419165260 3.358585e-02 0.5040722392
696 O43293 DAPK3 0.5693891008 5.910806e-02 -0.6285225768
697 Q9Y666 SLC12A7 0.6011450211 1.239458e-01 -0.4381618809
698 Q13243 SRSF5 -0.9385942458 2.054642e-08 -0.3170640659
699 O60783 MRPS14 -0.0066880886 9.775133e-01 -0.5086372728
700 P07919 UQCRH 0.1359094849 6.906027e-01 -0.5651417812
701 Q9NX63 CHCHD3 1.0427572607 2.935836e-04 -0.3277408282
702 P55084 HADHB -0.2677472580 1.547869e-01 0.2097034528
703 P13489 RNH1 -0.0706709931 6.871579e-01 0.4345200177
704 Q96DI7 SNRNP40 0.9869211353 2.164541e-09 -0.1970792390
705 Q7L2J0 MEPCE 0.2026658218 3.182126e-01 -0.5611017091
706 Q96BY9 SARAF -0.0647009289 7.866349e-01 0.4949614588
707 P35580 MYH10 0.1599521080 5.234833e-01 0.2579626136
708 Q702N8 XIRP1 0.6888344015 9.755848e-02 0.3451051635
709 Q9NZJ4 SACS -0.1521014978 6.314397e-01 0.2581561934
710 P10253 GAA -0.1872497079 3.260615e-01 0.2597096574
711 P13693 TPT1 -0.3736870386 1.059118e-01 0.3488953735
712 P25787 PSMA2 -0.3411146970 1.154110e-01 0.2237141090
713 Q15059 BRD3 -0.0642290127 7.380837e-01 0.7008214340
714 P62829 RPL23 -0.0375054703 8.722541e-01 -0.2495856064
715 P02751 FN1 0.4059860559 6.382477e-01 -0.6182199049
716 P23526 AHCY -0.4200199217 4.021328e-04 0.3846324108
717 Q14108 SCARB2 -0.5811844517 6.050463e-02 0.3501590830
718 Q92692 NECTIN2 0.3327029312 1.442756e-01 0.3587154090
719 Q13595 TRA2A 0.5837181309 1.118645e-05 -0.3544887951
720 Q14103 HNRNPD 0.6137841986 1.798761e-03 -0.2356367552
721 Q14687 GSE1 0.4615816199 2.834109e-02 0.3011342509
722 O00442 RTCA 0.0497484933 7.143912e-01 0.3236586076
723 P22392 NME2 0.6019933568 7.480706e-03 0.2216193309
724 P55145 MANF 0.5420947519 5.951120e-02 -0.4247296304
725 Q9BQA1 WDR77 -0.3514704546 3.562026e-03 1.0060757957
726 Q96T37 RBM15 -0.1629125831 5.332425e-01 -0.3326641434
727 P62312 LSM6 0.4407276866 5.295960e-02 -0.4824660783
728 P62341 SELENOT -0.0028886621 9.902110e-01 -0.3898158084
729 O43795 MYO1B -1.0346866233 1.283428e-04 0.3917883122
730 Q9NVH0 EXD2 1.1161067985 1.377560e-08 -0.6313561384
731 Q53S58 TMEM177 1.6642066794 3.698369e-06 -0.4765063730
732 Q8N2K0 ABHD12 -0.2813628352 5.984460e-03 0.4113335486
733 Q7Z478 DHX29 0.5915033898 8.893336e-07 -0.5521116291
734 P22059 OSBP 0.2496588428 7.648157e-02 -1.5819245055
735 O14929 HAT1 0.8951330995 2.332618e-03 0.7983739285
736 P40925 MDH1 0.5631077569 8.819686e-02 0.2955321084
737 Q15424 SAFB 0.0150735999 9.393487e-01 -0.2113807956
738 Q8IZD9 DOCK3 -1.9038208031 2.826730e-05 -0.4601150657
739 Q9Y2R5 MRPS17 0.4574472322 1.611673e-02 -0.2305341454
740 O15164 TRIM24 -0.4664298084 6.385852e-02 -0.3100285550
741 O15143 ARPC1B -0.2565048751 5.251166e-01 0.2949767775
742 Q9UJU6 DBNL -0.2499848751 6.816093e-02 0.5606788831
743 Q9NR31 SAR1A 0.2363214759 1.614588e-01 0.1959339329
744 P11047 LAMC1 -0.1406192194 5.612558e-01 0.2901354561
745 P08133 ANXA6 0.9749843576 9.887322e-12 0.3743442056
746 Q9NR50 EIF2B3 0.5703202424 5.512294e-05 0.4164645917
747 Q6P2E9 EDC4 0.4108529510 1.252629e-02 0.2671590393
748 P07947 YES1 -1.2189749153 6.403973e-06 0.8030695959
749 Q13867 BLMH 0.1776476793 3.490101e-01 0.3373069173
750 Q9NZN3 EHD3 0.2435280219 4.288570e-01 0.1925063729
751 Q16762 TST -1.4379139834 8.395059e-10 0.2678680274
752 Q14BN4 SLMAP 0.6937765036 9.737918e-02 -0.6357207592
753 P49914 MTHFS 0.5510523939 8.411946e-02 -0.3727031427
754 P17931 LGALS3 -2.5929374784 2.490015e-12 0.9625827295
755 Q86V15 CASZ1 0.8639407478 1.565329e-03 -0.6604771128
756 Q9Y678 COPG1 0.1067590686 5.701039e-01 0.2606506039
757 P61088 UBE2N -0.1635906008 2.465348e-01 0.4780619425
758 P30038 ALDH4A1 -0.0038355019 9.917878e-01 0.1953479302
759 P26885 FKBP2 0.1433370710 4.421703e-01 -0.5035273514
760 Q96CW5 TUBGCP3 1.0142092917 1.681253e-08 0.2827323465
761 Q96T51 RUFY1 0.4127955103 3.713102e-04 0.2433044713
762 P15289 ARSA -0.6910198170 4.722300e-04 0.3370065119
763 Q09028 RBBP4 -0.0508643970 6.176985e-01 -0.2283178102
764 Q9NWT8 AURKAIP1 0.0206912716 9.398638e-01 -0.9917786351
765 Q8IUX1 TMEM126B 0.2342691077 3.325270e-01 -0.3178565596
766 O95319 CELF2 0.5525093287 1.349687e-03 -0.2973479666
767 O14744 PRMT5 0.3402711208 2.329948e-03 0.5622037955
768 P54646 PRKAA2 0.4755630769 1.349687e-01 0.3472953318
769 P07858 CTSB -1.0268972427 5.304533e-07 0.2022527967
770 P33176 KIF5B 0.1552245851 3.577067e-01 0.2534894382
771 Q9UDY4 DNAJB4 -0.7021476742 3.459294e-03 0.2982075190
772 Q96EY1 DNAJA3 0.1113988217 5.546771e-01 -0.3118180617
773 Q8N4L2 PIP4P2 0.1266681155 6.125831e-01 -0.3896896872
774 P11177 PDHB 0.2567833368 1.582214e-01 0.2136331629
775 P17174 GOT1 0.8094163135 1.441070e-02 0.3350182125
776 Q8IVP5 FUNDC1 -0.0092819535 9.811352e-01 0.4600303072
777 O14773 TPP1 -0.1834997747 4.230061e-01 0.2517810618
778 P40227 CCT6A -0.2531332079 1.627520e-01 0.2546402387
779 P38606 ATP6V1A -0.5007412522 1.660687e-01 0.2052176420
780 O75208 COQ9 0.1017936983 6.244844e-01 -0.3265285959
781 Q9Y241 HIGD1A -0.1579891207 5.315324e-01 -0.2504555886
782 Q15019 SEPTIN2 -0.2199549265 1.267210e-01 0.3261869153
783 Q9Y2B0 CNPY2 -0.1076399004 7.320698e-01 -0.4768480877
784 Q5JSH3 WDR44 -0.2588684197 1.173070e-01 0.3483007813
785 Q8TB61 SLC35B2 0.7906029307 1.825629e-03 -0.4518085483
786 O94925 GLS -0.9953780835 1.405469e-05 0.2333756716
787 O94851 MICAL2 -0.2176904615 5.697835e-01 -0.3030187814
788 Q6P9B9 INTS5 -0.5362100362 4.876540e-04 -0.3672135897
789 P19237 TNNI1 0.5409715269 4.832926e-01 -0.5832965628
790 Q8NI60 COQ8A -0.9926464570 7.613501e-04 0.2684334443
791 O43175 PHGDH 0.6948338219 4.589757e-03 0.3128419382
792 Q9H082 RAB33B -1.2739844415 2.469365e-08 0.5793168823
793 Q00688 FKBP3 0.0120297357 9.664295e-01 0.3469715716
794 Q8N5K1 CISD2 0.7865389802 6.443198e-04 -0.2494762484
795 Q53GQ0 HSD17B12 -0.2050903596 4.474464e-01 0.2636347396
796 Q15119 PDK2 0.9203529177 5.124475e-04 -0.4245385559
797 Q8NFZ8 CADM4 0.4605378959 1.349615e-01 0.3074889502
798 O75937 DNAJC8 -0.5934749336 2.457478e-07 -0.8903072704
799 P52788 SMS 0.5028428846 4.421612e-02 0.7752797052
800 Q9Y2G8 DNAJC16 -0.0896233969 6.038524e-01 -0.3926432183
801 Q9Y617 PSAT1 -0.1757422936 6.817153e-01 0.6649855107
802 Q7Z7B0 FILIP1 1.4561039118 2.580053e-06 -0.2594882676
803 Q9BZH6 WDR11 -0.1604207703 3.122814e-01 0.3077656887
804 O15160 POLR1C -0.3304019405 9.457277e-02 -0.5328005416
805 Q15717 ELAVL1 -0.1791772256 1.634265e-01 -0.2644192279
806 Q86VR2 RETREG3 -0.7348944119 4.591830e-04 0.9144363126
807 Q92544 TM9SF4 0.2604999245 1.576993e-01 -0.2630598716
808 Q7L2H7 EIF3M 0.4417920457 1.341720e-02 -0.4165979428
809 Q9P202 WHRN -3.7907907294 5.296885e-18 -0.4396852898
810 Q14315 FLNC 0.0091980102 9.797195e-01 0.2407867819
811 O14579 COPE -0.1899210959 2.457766e-01 -0.4194876561
812 Q9BVC6 TMEM109 1.0778444594 1.278189e-07 0.2159356176
813 Q8NHP8 PLBD2 0.0427569679 8.842507e-01 0.2536745160
814 O95373 IPO7 -0.7179835937 4.379434e-05 0.2658177394
815 Q8NBN7 RDH13 0.5405853327 1.313719e-01 -0.3638958128
816 Q12849 GRSF1 -0.2797399863 2.235376e-02 -0.2447808690
817 O15294 OGT 0.2622533078 1.383752e-01 -0.3081091741
818 Q9Y639 NPTN 0.2451096282 2.439584e-01 0.2648427227
819 P07948 LYN -0.2187979779 3.709284e-01 0.2004440899
820 Q9HC07 TMEM165 -0.0768647081 8.169991e-01 -0.2575657257
821 Q86YM7 HOMER1 0.2049307776 6.395442e-01 -0.2236535786
822 Q9UBF2 COPG2 -0.2187991718 3.184513e-01 0.8256921260
823 Q8IXB1 DNAJC10 0.5575281221 9.531126e-03 0.2569521756
824 Q9UNL2 SSR3 0.8247432844 1.175747e-04 -0.4034222028
825 Q9P2E9 RRBP1 0.1485374403 7.794919e-01 -0.3297708482
826 P49790 NUP153 0.2273400159 1.240236e-01 -0.3131665674
827 O95674 CDS2 0.6041098732 1.248110e-02 0.6374003101
828 Q15459 SF3A1 0.0149075549 9.416420e-01 -0.2070695644
829 Q6ZUS5 CCDC121 -0.3088625409 2.057986e-01 -1.0874069922
830 Q9UGI8 TES -0.2718416723 3.820426e-01 0.2629903558
831 Q96KA5 CLPTM1L -0.3461131673 1.449524e-01 0.4813606706
832 Q5JRX3 PITRM1 -1.4530277020 2.719314e-08 0.2504261087
833 Q9Y6G9 DYNC1LI1 -0.1959136088 1.442756e-01 0.2240779488
834 O14936 CASK -0.8152996245 6.393939e-03 0.2772116486
835 Q9NTX5 ECHDC1 0.2091493103 9.763701e-02 0.3097828770
836 Q96RT6 CTAGE1 0.4989257122 6.211457e-02 0.2580294367
837 P29966 MARCKS -0.6166755034 2.937736e-01 -0.5430377812
838 P06576 ATP5F1B 0.3304109780 3.478027e-02 0.2189506192
839 Q8NFV4 ABHD11 0.3292054123 1.093639e-01 -0.3398481794
840 O95817 BAG3 -0.4577460200 7.042418e-03 -0.6677963911
841 Q9BXJ9 NAA15 0.6306292851 9.605473e-06 -0.3740103288
842 Q96MV1 TLCD4 0.3443623814 4.219153e-01 0.2623120849
843 Q9NR45 NANS 0.0351492231 8.996647e-01 0.3146913223
844 P63241 EIF5A 0.3063341986 1.163757e-01 0.2769532214
845 Q8N766 EMC1 -0.0148415365 9.703914e-01 0.2279321175
846 Q9UHX1 PUF60 0.1308349073 3.871955e-01 -0.2098946096
847 Q14739 LBR 1.3656942419 2.574362e-06 0.2734819331
848 Q9BVS5 TRMT61B 0.1689631584 2.887540e-01 -0.4735072436
849 P22570 FDXR -3.0490137809 6.494646e-15 0.3135655531
850 Q6JQN1 ACAD10 0.4163115983 9.914669e-02 0.2456100233
851 Q12792 TWF1 0.1212247041 7.804761e-01 -0.5774892398
852 O60762 DPM1 -0.3015365935 8.012789e-02 -0.2377234491
853 Q96IP4 TENT5A -1.2399342896 5.565489e-08 1.1728031062
854 O15230 LAMA5 0.4447570795 1.072857e-01 -0.5469555280
855 P31323 PRKAR2B 1.2817323071 1.231591e-03 0.3632298261
856 Q9NRW7 VPS45 0.6171724986 1.884764e-04 0.2653227724
857 O76094 SRP72 0.4813531766 2.927449e-02 -0.2458223900
858 Q9NX14 NDUFB11 0.2929721988 2.570118e-01 -0.2311935849
859 Q8NF91 SYNE1 0.0363200034 9.112240e-01 -0.4360386458
860 O75915 ARL6IP5 -0.0069882044 9.721511e-01 0.2602322904
861 Q9Y6N1 COX11 -0.3963814121 1.567336e-03 0.8089524574
862 Q9NX61 TMEM161A 0.6897117325 1.251528e-04 -0.5679989932
863 P53992 SEC24C -0.0527575479 7.224271e-01 -1.1668691275
864 Q14019 COTL1 -0.3691141983 6.429733e-01 0.6632140707
865 Q9NPD3 EXOSC4 -0.4595099214 4.728026e-03 -0.4989232971
866 Q8IWB9 TEX2 0.3794846960 2.614909e-02 -0.2596002743
867 P35080 PFN2 0.5231094827 1.094566e-02 0.4131442460
868 Q9BX46 RBM24 0.2943106489 3.352250e-01 -0.3530349822
869 P11233 RALA -0.4600139862 2.007882e-03 0.2179385173
870 Q9P2W9 STX18 0.0238119456 8.787580e-01 -0.2484726219
871 Q8N3E9 PLCD3 -0.1796994289 3.699624e-01 0.2207670998
872 P05165 PCCA 1.0108453414 2.818499e-07 0.1902944993
873 P47755 CAPZA2 0.1417976794 6.301749e-01 0.2758038835
874 P39060 COL18A1 0.4101545222 1.816848e-02 -0.3024581704
875 O60306 AQR 0.1084464144 5.727434e-01 -0.6041590902
876 Q9H4M9 EHD1 -0.9635804815 3.086698e-07 0.1800152817
877 Q7RTP6 MICAL3 0.2015549206 5.110727e-01 -0.2343073623
878 Q9Y262 EIF3L -0.0130205025 9.403779e-01 -0.2814381562
879 Q96J84 KIRREL1 0.6724886606 1.291765e-01 0.6706125423
880 O14925 TIMM23 0.1195718542 2.140039e-01 -0.2276745311
881 Q8IYI6 EXOC8 -0.4093023401 1.707838e-03 0.6349943165
882 P50993 ATP1A2 1.4675780543 1.988062e-02 -0.2577987166
883 O14653 GOSR2 -0.1260510994 2.596516e-01 -0.3243496360
884 P25705 ATP5F1A 0.4306473723 1.132568e-02 0.2257005707
885 Q8IWB7 WDFY1 -0.7829870674 8.936408e-03 0.7064385530
886 Q9BS92 NIPSNAP3B -0.1324233067 6.953143e-01 0.2694926792
887 Q15404 RSU1 0.8263313732 2.441850e-04 -0.5275078037
888 O00422 SAP18 -0.8366488364 8.327475e-05 -0.2535599295
889 Q7Z3B4 NUP54 0.1466943110 5.563617e-01 1.8506747811
890 Q9P2J5 LARS1 0.5978709437 1.600134e-07 0.2285428331
891 P62495 ETF1 -0.3965590239 1.851360e-03 0.3631770352
892 P26038 MSN 0.4133762823 2.478151e-01 0.1709112499
893 P30041 PRDX6 -0.8741911770 9.707431e-07 0.2881943921
894 Q9Y2D4 EXOC6B -0.0919038948 6.236365e-01 0.6507001381
895 Q8N465 D2HGDH 0.0259624405 9.062350e-01 0.2672801369
896 Q92688 ANP32B 0.4804698795 8.123762e-03 0.3991123511
897 Q6STE5 SMARCD3 0.8576798083 1.141002e-05 -0.2675357203
898 O95881 TXNDC12 0.4742654502 8.991521e-03 -0.3698129169
899 Q9Y2Q9 MRPS28 0.5024745440 6.207591e-02 -0.9935453361
900 Q14203 DCTN1 0.2309867566 8.641046e-02 0.2375835105
901 O15382 BCAT2 0.4597613267 4.616915e-04 0.2498531004
902 P53041 PPP5C 0.9762585878 2.639922e-12 0.3091713831
903 O94874 UFL1 0.8424211554 1.200925e-06 -0.2854740636
904 Q96K17 BTF3L4 -0.0694849844 6.937699e-01 -0.6777132062
905 Q96RT1 ERBIN -0.1093053646 4.506383e-01 -0.3295656488
906 Q16795 NDUFA9 0.7323482247 3.964602e-05 0.1927761825
907 Q92599 SEPTIN8 0.5157063915 1.160454e-02 0.2024064979
908 P51398 DAP3 0.9266599244 1.774996e-07 -0.2499363600
909 Q5T4S7 UBR4 0.2486941173 2.676098e-01 0.5108829847
910 Q15417 CNN3 -0.7253456121 4.411046e-03 0.4565561668
911 Q8WUM4 PDCD6IP -0.5149553377 2.683067e-05 0.4075451648
912 Q9BYC9 MRPL20 0.1903756584 2.196497e-01 -0.5383363165
913 P58335 ANTXR2 0.1195977762 5.422546e-01 0.5629312410
914 Q15046 KARS1 0.1606257612 1.723397e-01 0.2374029245
915 Q03135 CAV1 -0.9300855868 7.400782e-02 0.1995018439
916 P04083 ANXA1 -0.0461632255 9.631503e-01 0.3359523597
917 Q15006 EMC2 0.6095726321 1.922097e-03 -0.3710452243
918 Q14517 FAT1 -0.8459858648 2.906147e-02 -0.9700068016
919 P0DP25 CALM3 0.3042375830 6.089589e-02 -0.5683668420
920 A2RRP1 NBAS 0.6358297250 1.124990e-04 -0.3033480951
921 P49321 NASP 0.0313830414 9.208014e-01 0.3808527490
922 Q14112 NID2 0.6089685079 1.261899e-01 -0.7753149080
923 P99999 CYCS 0.0493396030 8.807324e-01 -0.2130178742
924 P13929 ENO3 0.6449258844 1.389299e-01 0.3775704797
925 Q9HBU9 POPDC2 1.5945344204 2.724736e-03 -0.1759774239
926 P13798 APEH 0.2795448974 1.995638e-02 0.2389391661
927 Q92896 GLG1 0.0038275416 9.898522e-01 -0.2389296568
928 Q8N9F7 GDPD1 1.0732167208 8.957472e-04 -0.3218915392
929 O14950 MYL12B -0.6752782282 3.702169e-03 -0.4581729650
930 Q07157 TJP1 0.2930951888 6.588620e-02 -0.1907873045
931 Q9NV70 EXOC1 -0.2665690554 5.567732e-02 0.3095148387
932 P23786 CPT2 -1.1480949718 8.048024e-10 0.2091800381
933 Q9H000 MKRN2 0.3287332771 3.432010e-02 -0.7303962642
934 Q330K2 NDUFAF6 -0.8849238742 2.421835e-06 -0.6975382642
935 P17568 NDUFB7 0.3570215949 3.132859e-01 -0.4652801960
936 Q12905 ILF2 0.0387615287 8.313867e-01 -0.1636565050
937 Q00325 SLC25A3 0.6990663237 9.659669e-05 0.2434013775
938 P50990 CCT8 -0.1151594169 5.083174e-01 0.2098631154
939 Q9UKF6 CPSF3 -0.5498634751 6.118418e-06 0.5202758716
940 Q9H8M1 COQ10B 0.0040928588 9.850060e-01 -0.4021494489
941 Q08431 MFGE8 -0.7693245664 4.736294e-05 0.3344022603
942 Q8N4T8 CBR4 -0.7289628455 4.513419e-06 0.1957529169
943 Q9H553 ALG2 -0.2861101188 8.623609e-02 0.2221531721
944 Q13523 PRPF4B 0.0835591922 6.686509e-01 -0.3213637053
945 Q96A23 CPNE4 0.4401121522 5.161763e-01 0.3283358372
946 Q9Y6A4 CFAP20 0.2975429444 2.924956e-02 -0.2432424196
947 Q99460 PSMD1 -0.0400776179 7.032391e-01 0.1755410750
948 O94903 PLPBP 0.0284779230 8.799214e-01 0.3035410868
949 O00139 KIF2A 0.0099644132 9.620962e-01 0.5817846082
950 P14927 UQCRB 0.0231759786 9.531766e-01 -0.3014341275
951 Q9UMS4 PRPF19 0.0397906442 8.634162e-01 -0.2416057330
952 P28072 PSMB6 -0.2977006176 1.737828e-02 0.1629178650
953 O94760 DDAH1 -1.2222651325 6.451953e-04 0.6363531350
954 P51572 BCAP31 -0.5535838131 3.579409e-03 0.2609031879
955 O43155 FLRT2 -0.6565364545 4.780275e-02 -0.4750531410
956 Q01449 MYL7 0.5336212558 1.283220e-01 -0.4080785114
957 Q13617 CUL2 -0.0594813383 6.476079e-01 0.2439321263
958 Q2PPJ7 RALGAPA2 0.6569275809 5.158838e-03 0.5746045275
959 O14880 MGST3 0.3067880393 4.060940e-01 0.2074988516
960 Q6P6C2 ALKBH5 -0.1189052691 7.091700e-01 -0.5049489697
961 P55209 NAP1L1 -0.6201325860 2.092402e-04 0.2863524381
962 P55036 PSMD4 -0.0964899280 3.805719e-01 0.1776812272
963 Q9HD33 MRPL47 0.2554762149 2.760215e-01 -0.3659727073
964 Q96DZ1 ERLEC1 0.1565713350 4.134580e-01 0.4692238398
965 Q96RF0 SNX18 -0.8066293130 4.146307e-03 -0.9094283446
966 Q8WWA1 TMEM40 -0.5402682566 1.535104e-01 -0.7748569766
967 O75131 CPNE3 0.0006017617 9.978874e-01 0.2697861351
968 O15273 TCAP 2.2881799287 2.927843e-02 0.3182510946
969 Q9Y2K3 MYH15 -0.7504523419 2.827785e-01 -0.5962386272
970 Q13148 TARDBP -0.2767561140 7.834289e-02 -0.2052262160
971 Q6ZRY4 RBPMS2 -0.4218662355 1.668584e-01 -0.5207844372
972 Q15287 RNPS1 -0.2382835791 8.198952e-02 -0.3093679118
973 O95822 MLYCD -0.1976594742 5.064806e-01 0.2195562657
974 O75534 CSDE1 -0.0653691148 6.954938e-01 -0.3217653128
975 Q9BSH4 TACO1 0.1071798699 7.162095e-01 -0.2463987244
976 Q9Y295 DRG1 0.4343534097 3.144624e-03 -0.2042030230
977 Q8IWA4 MFN1 0.0355707901 8.638571e-01 0.3031254880
978 Q9UJ68 MSRA 0.0690531004 6.398019e-01 0.4520051600
979 O75438 NDUFB1 -0.1909603695 6.244175e-01 -0.4073721122
980 P48059 LIMS1 -1.1820329846 9.547417e-05 0.2845010920
981 O14521 SDHD 0.5553709774 1.676135e-02 0.6828707650
982 Q8IWX8 CHERP 0.1666658517 3.685543e-01 -0.2741827603
983 Q00013 MPP1 1.9427738598 2.286116e-14 0.2673576413
984 P07602 PSAP -0.1813243140 3.301339e-01 0.2996491858
985 P02768 ALB -0.1259893048 9.682887e-01 0.1813038996
986 Q5HYI8 RABL3 -0.0018235256 9.932990e-01 0.6096474811
987 P09110 ACAA1 0.0249357682 8.965306e-01 0.2525502788
988 Q2TAL5 SMTNL2 0.1467268953 8.101386e-01 -0.4179533925
989 Q9Y6Q9 NCOA3 -1.0777882364 5.852037e-03 0.3992454030
990 Q96DV4 MRPL38 -0.2212564061 1.553935e-01 -0.2845310764
991 O43670 ZNF207 0.1018045171 3.918009e-01 -0.9218539849
992 Q9P2B2 PTGFRN 0.7660902561 1.138043e-02 0.2236670180
993 Q9UKV3 ACIN1 0.3329212994 1.650592e-02 -0.2256838069
994 Q92665 MRPS31 0.3901754512 6.832485e-02 -0.2616878415
995 P61923 COPZ1 0.0766732085 5.611689e-01 -0.2853890358
996 P08559 PDHA1 0.1750477058 4.419413e-01 0.1983900169
997 Q7Z4W1 DCXR -0.8704833695 8.965092e-04 0.3260169770
998 Q93008 USP9X -0.3162855346 3.867037e-01 -0.4530244840
999 P57740 NUP107 0.3496003321 1.794755e-01 -0.3587798251
1000 Q8TB22 SPATA20 0.3148845355 2.051312e-01 0.1798405753
1001 Q15369 ELOC -0.6869531304 2.099688e-06 -0.2699784691
1002 Q9GZT3 SLIRP 0.1659760476 5.798608e-01 -0.2760344148
1003 Q9NX00 TMEM160 0.0612060409 7.969343e-01 0.4628996523
1004 O14494 PLPP1 -0.1518940764 6.540261e-01 -0.5747954452
1005 O15355 PPM1G -0.4927385661 1.466417e-03 0.8194855442
1006 Q9NQR4 NIT2 0.2387231413 1.813028e-01 0.2024662845
1007 P49750 YLPM1 0.3700886974 9.752070e-02 -0.2510595044
1008 Q9UBQ0 VPS29 0.2536104755 2.329681e-01 0.2006268126
1009 Q9ULQ0 STRIP2 -0.0883828464 6.892018e-01 0.2366328761
1010 Q5JTH9 RRP12 -0.5708116705 1.032103e-01 -0.2766978235
1011 P62826 RAN 0.6027384305 6.088563e-04 0.2216165615
1012 P55287 CDH11 0.2882049217 6.821621e-01 -0.7330076615
1013 Q5VU97 CACHD1 1.0177770023 2.709308e-06 -0.2798743420
1014 Q15363 TMED2 -0.0233466988 9.207356e-01 0.2339965755
1015 P56556 NDUFA6 0.5684564686 9.153004e-02 -0.1926233296
1016 P63096 GNAI1 -1.4218247399 6.830061e-11 0.3335997898
1017 O95302 FKBP9 -0.0463607365 8.461508e-01 0.2443602043
1018 A6NJ78 METTL15 0.7550515034 1.614602e-05 -0.4571510920
1019 Q9NRK6 ABCB10 0.5652114841 5.019931e-03 0.2190583824
1020 O14907 TAX1BP3 -1.4210392542 8.264307e-08 -0.3224757532
1021 Q9UKM7 MAN1B1 0.1752593770 6.193836e-01 -0.5574282159
1022 Q9UBP4 DKK3 -0.2319026104 2.605354e-01 0.6821042386
1023 P12259 F5 -1.2386880915 3.470117e-01 0.4073259675
1024 P00387 CYB5R3 0.0165754913 9.488212e-01 0.1694320838
1025 Q9H4G0 EPB41L1 -0.5669181959 7.434396e-03 0.3791705016
1026 P35475 IDUA 0.0329431435 9.156707e-01 0.4743598857
1027 P31942 HNRNPH3 0.0463689881 7.599386e-01 -0.6346268799
1028 P50395 GDI2 0.1680521407 1.594557e-01 0.2610576155
1029 O95168 NDUFB4 0.7850763904 2.159324e-03 -0.6440503004
1030 P07951 TPM2 0.0670765094 8.011362e-01 -0.6021338456
1031 P40939 HADHA -0.0439308007 7.533651e-01 0.1851041865
1032 Q96EE3 SEH1L 0.0478673574 7.581510e-01 0.4602912846
1033 Q16540 MRPL23 0.3033165534 2.267761e-01 -0.4441561464
1034 Q9Y2T2 AP3M1 0.6553017315 9.730282e-09 0.1684261992
1035 P40926 MDH2 -0.1236527959 4.502836e-01 0.2223211902
1036 Q9NS69 TOMM22 0.0087281260 9.484325e-01 0.3003760482
1037 P04156 PRNP -1.1410070974 1.808163e-06 0.2250199589
1038 Q92734 TFG 0.2145229437 8.071085e-02 0.2279689200
1039 Q969P6 TOP1MT -0.4056391210 4.035648e-01 0.8647687743
1040 P52943 CRIP2 1.0385478432 3.655249e-03 0.2739689260
1041 Q15124 PGM5 1.2411532464 1.554380e-04 0.2773011733
1042 Q9BSR8 YIPF4 -0.1859739698 3.744347e-01 -0.3012102796
1043 Q8WTT2 NOC3L 0.5412351347 1.358450e-02 -0.5317944608
1044 Q9BW60 ELOVL1 -0.1864125831 7.101723e-01 -0.4149351657
1045 P39687 ANP32A 0.8494308005 4.364201e-07 -0.9428756110
1046 P49757 NUMB -0.6263374138 4.012865e-07 0.7438829815
1047 P10768 ESD 0.6282585286 1.332894e-02 0.5347772205
1048 P98160 HSPG2 0.0249069355 9.418177e-01 -0.2947119636
1049 Q9ULE0 WWC3 -0.3287921351 5.397758e-02 0.3052709232
1050 P06756 ITGAV -0.0036628192 9.901463e-01 0.1883455390
1051 Q9UKX3 MYH13 2.6319240265 4.927442e-06 0.3484502872
1052 P13639 EEF2 -0.1466171035 2.744447e-01 0.2163254542
1053 Q969Q5 RAB24 -0.4136407272 5.400707e-03 0.3537539950
1054 Q9Y230 RUVBL2 0.1924869830 1.374833e-01 -0.2118808800
1055 Q6P2Q9 PRPF8 0.0199878345 9.227264e-01 -0.1645047624
1056 Q4G0N4 NADK2 -1.2451834616 5.944150e-10 0.3179150726
1057 P28161 GSTM2 0.3494152399 1.217532e-01 -1.0126528211
1058 Q99470 SDF2 -0.3121417375 7.928556e-02 0.2742877121
1059 P05141 SLC25A5 0.0323084281 9.470804e-01 0.1752388592
1060 P53582 METAP1 0.6066468278 7.599310e-04 -0.3068330790
1061 Q8TAD4 SLC30A5 0.7591393290 3.805658e-06 -0.3732777871
1062 P55060 CSE1L 0.2378893508 2.990434e-01 0.4091759109
1063 O15091 PRORP 0.8154014564 2.908861e-07 -0.2562552421
1064 P62873 GNB1 0.2528335485 2.274096e-01 -0.1777631605
1065 P04406 GAPDH 0.1275573809 7.411443e-01 0.2606249142
1066 Q8TC12 RDH11 0.8626611190 7.887052e-07 0.1652025327
1067 P49327 FASN -0.5962963684 5.396461e-02 0.4285017684
1068 P37268 FDFT1 -0.4778184988 6.654641e-03 0.4290734589
1069 Q96L91 EP400 0.2009817341 2.146727e-01 -0.4746403647
1070 P14618 PKM -0.4858103234 6.241861e-02 0.3185482785
1071 O43390 HNRNPR 0.5315895314 1.982246e-04 -0.1484957651
1072 Q13428 TCOF1 0.8468016143 1.085352e-06 -0.2276177324
1073 Q96A65 EXOC4 0.6058767415 5.968732e-05 0.3332367779
1074 Q14344 GNA13 -0.8495024713 1.904966e-08 -0.4145648161
1075 Q9BSH5 HDHD3 0.1458391930 7.273371e-01 -0.3785623189
1076 Q02790 FKBP4 -0.4219765300 2.970464e-02 0.2517632624
1077 P12532 CKMT1B 0.3189274908 4.609424e-01 0.3851066822
1078 P12532 CKMT1A -0.0184073314 9.706144e-01 0.3851066822
1079 O95747 OXSR1 -0.6930139820 1.682823e-05 -0.2969421867
1080 Q8WWC4 MAIP1 0.4513648139 1.399208e-02 -0.1604667632
1081 Q0ZGT2 NEXN 1.5557338253 5.934942e-06 -0.1712369163
1082 Q8WXF1 PSPC1 -0.1595771459 3.171161e-01 -0.2346862373
1083 P02649 APOE 0.4604001113 2.870514e-01 -0.4349334489
1084 O75439 PMPCB 0.2744611640 3.556375e-02 0.2474615548
1085 P11766 ADH5 0.6237013071 3.521814e-03 0.3431203127
1086 P52926 HMGA2 0.3196203987 5.375888e-01 -0.4825620433
1087 Q12904 AIMP1 0.0468284387 8.099196e-01 0.1472376419
1088 Q96CM8 ACSF2 0.5162424633 3.982095e-02 0.2109320371
1089 P60228 EIF3E 0.3908875813 5.770630e-02 -0.1934319770
1090 Q56VL3 OCIAD2 -0.3691745379 3.140993e-01 -1.1556235158
1091 P54803 GALC -0.3742303001 1.625391e-01 0.4053021635
1092 Q8NDX6 ZNF740 -0.3816940537 1.117693e-02 0.6161897468
1093 O60725 ICMT 0.1083662631 4.429647e-01 -0.4737800938
1094 Q6ZMG9 CERS6 0.6201730241 2.096873e-03 -0.4165891174
1095 Q9BWU0 SLC4A1AP -0.1415998358 2.117596e-01 -0.4005840378
1096 Q86VX9 MON1A 0.4727584757 5.124475e-04 -0.4942796745
1097 Q96EK5 KIFBP 0.9888310990 5.708229e-09 -0.4534656876
1098 P27348 YWHAQ 0.0515756392 7.512007e-01 -0.6274318586
1099 Q02952 AKAP12 -1.4315524123 2.048071e-03 -0.3310385676
1100 Q99720 SIGMAR1 0.4357987381 6.202618e-03 -0.1955697004
1101 P60660 MYL6 -0.1045768329 7.385530e-01 -0.3794384882
1102 Q969G3 SMARCE1 0.4652326113 5.866240e-04 -0.3907690326
1103 P25325 MPST 1.0954059223 3.036855e-09 0.3486364653
1104 Q9BYT8 NLN 0.2114194894 5.360158e-01 0.2497676276
1105 P54289 CACNA2D1 -0.0815651133 7.198256e-01 0.2886669420
1106 Q8WZ82 OVCA2 -0.4018782433 1.327398e-01 -0.1856533008
1107 P42574 CASP3 -1.6038011779 2.933546e-09 0.5822243824
1108 Q92558 WASF1 -1.0036354192 4.535845e-07 0.2895967574
1109 Q8NBX0 SCCPDH 0.6776929220 4.818857e-06 0.1643488603
1110 P13804 ETFA -0.2818442738 1.411864e-01 0.1860273983
1111 Q13643 FHL3 -1.0466605470 5.960147e-04 0.1756591781
1112 Q8WVC6 DCAKD -0.5719796571 2.568020e-02 0.1748852996
1113 Q9BSJ8 ESYT1 -0.6367166593 4.096170e-02 0.1886056449
1114 P55196 AFDN 0.2091178559 1.298005e-01 -0.2564127074
1115 O14807 MRAS 0.1120639937 6.429733e-01 0.4264170297
1116 Q8NBL1 POGLUT1 -0.6596242310 1.587475e-02 -0.3876724743
1117 P31150 GDI1 0.1686184919 2.946914e-01 0.6114273746
1118 O14529 CUX2 1.0336963276 6.178952e-02 0.4127866418
1119 Q15286 RAB35 -0.2780641932 1.109953e-01 -0.1915257928
1120 Q8NEY1 NAV1 1.9662442223 3.747903e-08 -0.4378139709
1121 Q8N3C0 ASCC3 -0.6486076404 8.401111e-03 -0.5238838638
1122 Q16595 FXN 0.6398030501 9.726706e-04 -0.3371877748
1123 Q9NWS8 RMND1 0.2602737035 6.081843e-02 0.2420462084
1124 Q9BY67 CADM1 -0.4034661933 1.815525e-01 0.2844115419
1125 P29279 CCN2 0.3821801087 6.180574e-01 -0.8798236579
1126 Q05048 CSTF1 0.2951151024 2.640275e-02 0.1715145274
1127 Q99497 PARK7 0.0583411647 7.139775e-01 0.2191932166
1128 P62258 YWHAE 0.3142248906 2.818680e-03 -0.4324579082
1129 P61224 RAP1B -1.5013856554 1.311531e-05 -0.3147737961
1130 Q16543 CDC37 -0.5108490580 1.215245e-05 0.8527218013
1131 Q01082 SPTBN1 -0.0048328352 9.875678e-01 0.1512178834
1132 Q96T76 MMS19 -0.5602189701 7.363503e-05 0.4412916923
1133 P12268 IMPDH2 0.2390327046 1.472817e-01 -0.2698557914
1134 O43766 LIAS 0.6649578996 6.135567e-03 -1.1289560057
1135 P54136 RARS1 -0.4148859560 9.917262e-03 0.1495354361
1136 P14314 PRKCSH 0.0562381883 8.270659e-01 0.2016706204
1137 P48728 AMT 0.6051898352 4.147509e-02 0.2171183611
1138 Q96CM3 RPUSD4 0.2274541467 4.557228e-02 -0.3544502906
1139 P52756 RBM5 -0.1546649647 4.624358e-01 -0.8464717098
1140 P78344 EIF4G2 -0.4697120711 5.914711e-04 0.2593451257
1141 Q96GK7 FAHD2A -0.0165881490 9.235759e-01 0.2791955975
1142 Q8IUR7 ARMC8 0.4878246776 3.386954e-04 0.2030229675
1143 O75190 DNAJB6 0.4856672435 2.079892e-03 -0.2459882156
1144 Q16181 SEPTIN7 0.2802200640 1.432851e-01 0.2438979297
1145 O00429 DNM1L 0.6162961656 1.113388e-07 0.1755736706
1146 Q5T9L3 WLS 0.0530897999 8.330211e-01 -0.3865169903
1147 P49916 LIG3 0.4922429801 1.582479e-04 0.1707692990
1148 O43818 RRP9 -0.3284797629 5.104956e-02 0.5894990859
1149 P30085 CMPK1 -0.2729015270 2.130730e-01 -0.1933908597
1150 Q8NBS9 TXNDC5 0.4876545122 3.085543e-01 0.2019894057
1151 O15121 DEGS1 0.7115466365 1.713023e-03 -0.4371204792
1152 Q6ZV73 FGD6 0.2367997872 1.673359e-01 0.2874082823
1153 Q9GZR7 DDX24 -0.4542717013 2.459383e-02 -0.3096223957
1154 Q9UKN8 GTF3C4 -0.3939530826 7.672568e-02 -0.6266017327
1155 P51151 RAB9A 0.1237132687 6.844126e-01 -0.5759567126
1156 Q5VWP3 MLIP 1.4082377847 7.629580e-04 -0.1938196858
1157 P51665 PSMD7 -0.0126233128 9.413936e-01 0.1505964723
1158 Q9C0H9 SRCIN1 -0.3524688080 4.091536e-01 0.2171637939
1159 Q04917 YWHAH 0.2689926137 9.321517e-02 -0.4586416160
1160 Q7Z7N9 TMEM179B -0.7344085789 1.156193e-04 0.6261185914
1161 Q5UCC4 EMC10 0.2168141134 1.543301e-01 0.2690058380
1162 L0R6Q1 SLC35A4 0.8696231556 1.008397e-06 0.7132840229
1163 Q6UXN9 WDR82 0.0767347774 5.205339e-01 -0.3073078218
1164 Q8TCZ2 CD99L2 -0.0878460353 5.362211e-01 -0.3654760179
1165 Q5SYB0 FRMPD1 1.9818177950 2.144046e-04 0.4304354667
1166 P18206 VCL -0.0116573432 9.620962e-01 0.1625168061
1167 Q96MF6 COQ10A 0.1370566562 7.792366e-01 -0.5899767781
1168 O43290 SART1 -0.0824654706 5.621323e-01 -0.2948589306
1169 Q9NUQ7 UFSP2 0.4863813235 4.128438e-03 -0.4890693930
1170 P63167 DYNLL1 -0.5080263356 4.269633e-04 -0.4776309632
1171 Q99519 NEU1 -0.8060382687 1.349653e-04 0.2340729081
1172 Q9UKX7 NUP50 0.3178479574 8.032711e-02 0.4563067949
1173 Q9UBQ7 GRHPR 0.2494752880 3.913320e-01 0.1623730725
1174 Q8N4V1 MMGT1 0.2107773991 1.970990e-01 -0.3831556700
1175 P07954 FH 0.2011052174 3.531808e-01 0.1758702593
1176 Q8N163 CCAR2 -0.5003892785 1.148994e-03 -0.2234923015
1177 Q12800 TFCP2 0.3945259094 1.125052e-01 -0.8942465762
1178 P11216 PYGB 0.3706804227 2.218133e-01 0.2592249446
1179 P09493 TPM1 1.2522744866 4.075438e-04 -0.5195783053
1180 Q8IVF4 DNAH10 -0.9839650884 1.487763e-03 -0.6988988483
1181 Q5SVZ6 ZMYM1 1.4001510972 1.082586e-10 0.5097142713
1182 P18085 ARF4 -0.6154930300 1.344725e-02 0.2406756720
1183 Q8IZ52 CHPF -0.1520880634 4.751689e-01 0.6396365429
1184 P19525 EIF2AK2 0.1609265130 5.373424e-01 0.3289154011
1185 P37837 TALDO1 0.5147243339 7.599499e-05 0.3275565224
1186 P41252 IARS1 0.2027621499 1.155138e-01 0.3010367691
1187 Q9Y697 NFS1 0.4748574691 2.356207e-03 0.2601530251
1188 Q6IQ26 DENND5A 0.3579760163 5.329381e-02 0.2819111601
1189 Q96CU9 FOXRED1 0.7669916720 3.126725e-03 0.1623620999
1190 Q8TDX7 NEK7 0.0397505828 9.218093e-01 0.2370851894
1191 O75390 CS 1.1967109946 1.105975e-08 0.2019558931
1192 Q99798 ACO2 0.3624162228 3.742887e-02 0.1737075649
1193 Q9H987 SYNPO2L 0.4677785726 1.764840e-01 -0.2173125110
1194 Q8WUA4 GTF3C2 0.1565539482 3.922664e-01 0.2645293192
1195 P15927 RPA2 0.6335135818 3.158478e-04 0.5900679915
1196 Q15413 RYR3 0.3365342196 5.161763e-01 0.4907422965
1197 P61081 UBE2M -0.0260307838 9.041815e-01 0.3808241832
1198 Q5BJF2 TMEM97 0.1622419885 5.904522e-01 0.4124106934
1199 Q96CS3 FAF2 -0.1597987456 3.988428e-01 0.2017451620
1200 P78362 SRPK2 -0.4640259359 2.829528e-04 -0.3561675508
1201 Q9NS86 LANCL2 -0.2007028884 3.025541e-01 0.5336491286
1202 Q9BQ69 MACROD1 0.2563418328 6.744580e-01 -0.3061545662
1203 Q96N66 MBOAT7 -0.6330062537 1.683402e-02 0.2051623271
1204 Q13409 DYNC1I2 -0.4299918990 1.980653e-03 0.2249566098
1205 P47813 EIF1AX -0.0412253155 8.756696e-01 -0.5763856120
1206 P62995 TRA2B 0.8662104375 3.205397e-10 0.2357465745
1207 Q5T440 IBA57 -0.3729151474 1.173489e-02 0.1572735744
1208 P33992 MCM5 2.5385286100 7.953892e-08 -0.4266690391
1209 Q9H1C7 CYSTM1 -0.5429026984 1.530673e-02 -0.2042284216
1210 Q99805 TM9SF2 0.0518010183 7.881137e-01 -0.2996303088
1211 Q9HCG7 GBA2 0.1452445581 5.913134e-01 0.6715095217
1212 Q7Z434 MAVS 0.1179006213 5.258659e-01 -0.2201294849
1213 O95140 MFN2 0.6211688186 1.353209e-03 0.1736514536
1214 P67936 TPM4 0.7288517470 1.204219e-01 -1.3145986683
1215 Q9NW81 DMAC2 0.4249282327 3.640322e-02 0.7093298005
1216 P06744 GPI 0.5731296492 1.195410e-01 0.2989626569
1217 P11388 TOP2A 2.5453095174 4.335829e-07 0.2831782862
1218 Q8IXI1 RHOT2 0.2257658276 2.679636e-01 0.1829881949
1219 Q86UT6 NLRX1 -1.4935468157 1.188060e-09 0.1727044734
1220 P61289 PSME3 -0.1551700705 2.936398e-01 -0.3186488922
1221 O00264 PGRMC1 -0.1643681228 5.832608e-01 -0.3144666001
1222 O96011 PEX11B 0.2246029516 2.006356e-01 -0.4070909886
1223 Q9Y2R0 COA3 0.7124130525 9.633384e-03 -1.0563885795
1224 O43837 IDH3B -0.2117197571 2.465050e-01 0.1745584763
1225 Q9Y625 GPC6 2.1561393996 5.386425e-08 -0.5029000042
1226 Q86T03 PIP4P1 -0.1920107847 2.215834e-01 0.2361481036
1227 Q9BZL4 PPP1R12C -0.1722368676 4.060347e-01 -0.4609433229
1228 Q9H425 C1orf198 0.1918442593 4.730758e-01 -0.2446437360
1229 P29373 CRABP2 -0.5694131325 1.275539e-01 0.5833966568
1230 O00483 NDUFA4 -0.0935414601 8.187737e-01 -0.1548613881
1231 Q9BVL2 NUP58 -0.0962208544 5.154703e-01 0.4128067530
1232 Q8NBJ9 SIDT2 -2.1821899647 4.994420e-11 0.1777699194
1233 P49406 MRPL19 0.3354281979 3.559057e-02 -0.1866633396
1234 Q8IX03 WWC1 -1.6684211550 8.573148e-04 -0.5816565682
1235 Q10472 GALNT1 0.0221855095 9.321867e-01 -0.3390812803
1236 Q02878 RPL6 -0.1665519442 2.233610e-01 -0.1699608569
1237 P20339 RAB5A -0.4581357504 2.769122e-03 -0.1952687252
1238 Q8NBI6 XXYLT1 0.2742338750 1.110262e-01 0.2879622067
1239 Q96PK6 RBM14 -0.0882873299 7.646341e-01 -0.1602658956
1240 P12236 SLC25A6 0.3566280473 7.825277e-02 0.2312047675
1241 Q9Y6E2 BZW2 0.7262709175 1.363170e-02 0.4040859421
1242 Q8IVH4 MMAA -0.6684583600 8.023218e-05 0.4118128987
1243 Q8N357 SLC35F6 -0.1557783728 5.992235e-01 -0.9284861958
1244 Q96RL7 VPS13A 0.1572218831 4.644663e-01 0.2389143229
1245 Q00796 SORD -0.2923900264 2.679636e-01 0.2646324357
1246 Q9Y281 CFL2 0.4869382091 5.488877e-02 -0.2704586228
1247 P30043 BLVRB -2.0859019736 1.324293e-11 0.4176070938
1248 Q7RTV0 PHF5A -0.3088479011 8.362302e-02 0.1821132685
1249 P31689 DNAJA1 -0.6821528472 2.591641e-06 -0.1702417740
1250 O95182 NDUFA7 -0.3041434870 4.695476e-01 -0.2823055399
1251 Q70UQ0 IKBIP -2.5968791300 1.312041e-08 -0.4258268925
1252 Q01130 SRSF2 1.3161428264 2.203715e-13 -0.1757609362
1253 Q8IUW5 RELL1 -0.9659703540 5.544404e-03 0.4383245957
1254 Q15700 DLG2 0.2863520456 4.632790e-01 0.3382206433
1255 Q01844 EWSR1 0.3213996649 1.945372e-03 -0.1795997354
1256 Q63ZY3 KANK2 -0.1363736576 6.866698e-01 0.2702748502
1257 Q9UGJ0 PRKAG2 0.7936863964 2.199838e-04 0.2038104192
1258 Q9NZW5 PALS2 -0.1629946832 5.024194e-01 -0.3516237777
1259 Q8N335 GPD1L -1.3979714290 5.775641e-06 0.2670420996
1260 Q9UBW7 ZMYM2 -0.3256196612 8.150065e-02 -0.8711726993
1261 O95197 RTN3 0.5732234253 5.001978e-05 0.1595146606
1262 O94906 PRPF6 -0.0631869873 6.972857e-01 -0.2087853647
1263 P53007 SLC25A1 -0.0156444912 9.432795e-01 0.1674328582
1264 P09622 DLD 0.5596219860 1.646930e-02 0.1663956233
1265 Q9HBL0 TNS1 1.5841964540 6.973185e-05 -0.2565113346
1266 O15173 PGRMC2 0.8576537752 1.729944e-05 -0.2180495810
1267 O60869 EDF1 0.0935117587 5.358371e-01 0.3151733118
1268 Q9NYK5 MRPL39 -1.1662315660 3.597863e-06 -0.1484128380
1269 Q96PD2 DCBLD2 0.1316710309 6.968809e-01 -0.7323248288
1270 A4D1E9 GTPBP10 0.2891125963 1.640769e-01 -0.2908210346
1271 P82930 MRPS34 1.0870852877 2.162139e-07 -0.2525067136
1272 Q9Y4F1 FARP1 0.5041133248 1.693429e-02 0.2126862545
1273 P28070 PSMB4 -0.3870507288 1.778245e-03 0.1913990895
1274 O15371 EIF3D -0.1383335046 3.323825e-01 -0.1797804518
1275 O95229 ZWINT 2.1556045824 3.197079e-06 -0.2296707827
1276 P24752 ACAT1 -0.0248016224 9.225443e-01 0.1822936202
1277 Q92621 NUP205 1.2512749595 1.883758e-07 0.1957930676
1278 Q9NZ08 ERAP1 -1.0814621888 7.124195e-04 0.2536459915
1279 Q9UKX5 ITGA11 0.0411507027 9.696183e-01 -0.8492074981
1280 Q9NXF1 TEX10 -1.2219378568 1.730844e-07 -0.1956753243
1281 O60830 TIMM17B 0.4848448634 8.123777e-02 0.2971402877
1282 Q8IYK4 COLGALT2 0.2996215758 5.029982e-01 0.3103938096
1283 P29590 PML -2.0234028242 1.022548e-10 -0.8965424131
1284 Q9BUB7 TMEM70 -0.1382877334 5.086063e-01 0.1737179212
1285 Q9UHG3 PCYOX1 -0.0941640821 7.066130e-01 0.1451491849
1286 Q9UGM6 WARS2 -0.0220872871 9.065459e-01 0.2278769792
1287 Q14161 GIT2 -0.5935467767 1.131321e-03 0.3041902391
1288 P16070 CD44 -0.6017436142 2.437847e-01 0.4748070915
1289 Q96GG9 DCUN1D1 -0.5363147019 2.054383e-03 -0.2413307076
1290 Q9P0V9 SEPTIN10 -0.1467395687 5.602139e-01 0.3817066867
1291 P20674 COX5A 0.3123204036 2.851546e-01 -0.2240857927
1292 Q96AG4 LRRC59 -0.0065760286 9.811304e-01 -0.3024427746
1293 Q13510 ASAH1 0.1920116213 4.885160e-01 0.1810344084
1294 Q13740 ALCAM 0.6736856725 6.164576e-03 0.2368755761
1295 P61981 YWHAG -0.5825967230 5.124475e-04 -0.4018363757
1296 P05362 ICAM1 -3.1728344444 2.136255e-06 0.2277610361
1297 Q9BV81 EMC6 -0.4998517862 1.058354e-01 0.1921134483
1298 Q9P0J1 PDP1 -1.0137644623 2.814159e-07 0.1966753339
1299 P28074 PSMB5 -0.1744676482 1.875239e-01 0.1752998970
1300 P51798 CLCN7 -0.5351607685 1.358450e-02 -0.3937373400
1301 P14678 SNRPB -0.0171175039 9.485996e-01 -0.4266921252
1302 Q8WWY3 PRPF31 0.1817990400 1.877427e-01 -0.4769448034
1303 Q9BQE5 APOL2 0.1695596533 7.560025e-01 -0.4092360678
1304 P48552 NRIP1 -0.3031652618 1.394605e-01 0.3734020518
1305 Q92552 MRPS27 0.4896357530 5.956966e-06 -0.2499214918
1306 Q14669 TRIP12 -0.3217735245 2.396917e-03 -0.2132298260
1307 O95470 SGPL1 0.6106090065 2.816802e-03 -0.1458601456
1308 Q99590 SCAF11 0.4355917717 1.465209e-04 -0.5391192012
1309 P20073 ANXA7 0.2067953861 1.557194e-01 0.1856541714
1310 Q9Y6M1 IGF2BP2 0.4028236776 3.489404e-02 -0.1551044830
1311 Q9Y6Y0 IVNS1ABP -0.3483677379 1.585645e-01 0.1997982639
1312 P51589 CYP2J2 1.7911017443 1.188032e-03 -0.2083323637
1313 O75521 ECI2 -0.4605854024 6.925060e-03 0.1756689741
1314 P07711 CTSL -1.1932420348 2.660594e-05 0.1734064100
1315 Q9Y2W1 THRAP3 0.2584578608 1.147468e-01 -0.1526553555
1316 O15321 TM9SF1 0.2913228563 1.101212e-01 -0.5116488542
1317 P07237 P4HB 0.0540833049 8.043185e-01 0.1847757544
1318 P11717 IGF2R -0.6547762061 3.621031e-02 0.1760794914
1319 Q96A33 CCDC47 -0.0096495394 9.594684e-01 0.1839611026
1320 P51797 CLCN6 0.3068992915 7.583298e-02 -0.1437019702
1321 Q16134 ETFDH 0.1294769884 5.078204e-01 0.1691107558
1322 P13473 LAMP2 -0.0788987806 8.028234e-01 0.2558898146
1323 P52565 ARHGDIA -0.1099337515 7.084320e-01 0.1995929713
1324 P12004 PCNA -2.3246891718 6.129513e-12 0.2918815492
1325 Q9H6R3 ACSS3 0.4830666754 8.960703e-02 0.3293744375
1326 Q9H0U4 RAB1B 0.1402863905 2.887879e-01 -0.2557982811
1327 Q04637 EIF4G1 -0.1270788032 5.813380e-01 -0.1770725141
1328 Q6PML9 SLC30A9 0.1291828830 3.908375e-01 0.2414028600
1329 O00330 PDHX 0.0969681201 6.221394e-01 0.1818020732
1330 Q92878 RAD50 0.3013301993 1.539666e-01 -0.1886612531
1331 O43462 MBTPS2 0.9315136933 3.968384e-04 0.5602075722
1332 Q9H6F2 TMEM38A 0.4916124969 4.728673e-01 -0.4337233743
1333 P15121 AKR1B1 -0.2020262208 4.922021e-01 0.2168163302
1334 Q9NXE4 SMPD4 0.0245570685 8.854080e-01 0.3238087856
1335 Q8NEY8 PPHLN1 -0.7712157819 2.933686e-09 -0.2846316844
1336 Q13011 ECH1 0.0072142691 9.874831e-01 0.1774794224
1337 Q6NUQ4 TMEM214 0.2922292584 2.573985e-01 -0.2497138415
1338 P35658 NUP214 0.1114429427 5.316200e-01 0.1660316066
1339 Q567V2 MPV17L2 0.2715510733 7.679599e-02 -0.4270998235
1340 P61026 RAB10 0.8730113488 1.016052e-11 -0.1545494103
1341 Q6IAN0 DHRS7B 0.7459477690 3.290862e-07 -0.2038991202
1342 Q9Y3C6 PPIL1 0.4085145307 6.532447e-03 -0.4545700983
1343 Q9Y2S7 POLDIP2 -0.4774891546 5.888724e-07 0.2446095314
1344 P27824 CANX -0.1205830583 6.654446e-01 0.1711955194
1345 P63316 TNNC1 0.3950433855 3.828440e-01 -0.7257889002
1346 Q9H857 NT5DC2 -0.2455237401 2.135304e-01 0.1577193899
1347 Q9HB90 RRAGC -1.1930258462 5.051989e-08 0.1880983245
1348 Q9H3Z4 DNAJC5 -0.9422654275 2.119777e-04 -0.2396861754
1349 Q96HS1 PGAM5 0.7857049495 3.790385e-05 -0.1866335481
1350 P61964 WDR5 -0.0092351371 9.538291e-01 -0.1763420126
1351 Q5JWF2 GNAS -0.6305427339 4.178859e-04 0.1934172414
1352 Q01433 AMPD2 0.5567075681 1.992546e-03 0.3305181281
1353 Q9H2D6 TRIOBP 0.0427631222 8.567453e-01 0.1517306753
1354 P46087 NOP2 0.2945846607 1.998767e-01 -0.1703746942
1355 Q13057 COASY -0.1409929830 2.111999e-01 0.2133141718
1356 P22694 PRKACB -0.1742394335 2.677860e-01 -0.4304415165
1357 P60602 ROMO1 -0.3041029275 2.803242e-01 0.2595738896
1358 Q9UPT5 EXOC7 -0.7633202347 1.107584e-07 0.3537433291
1359 Q96BW9 TAMM41 1.8801846809 3.284402e-07 0.3625873956
1360 Q53EU6 GPAT3 -0.2746935698 4.102683e-01 -0.1526359695
1361 P51114 FXR1 0.2749105225 1.145534e-01 -0.1340646006
1362 Q13619 CUL4A 0.2717370544 1.213938e-02 -0.2727849206
1363 Q6L8Q7 PDE12 -0.3078127710 3.495553e-02 -0.4039064278
1364 Q96RQ1 ERGIC2 0.5416732220 7.785810e-03 -0.2213488910
1365 P12109 COL6A1 -0.3308760927 2.249124e-01 -0.1924487788
1366 Q96QK1 VPS35 -0.1229776835 4.482536e-01 0.1806870857
1367 Q16698 DECR1 0.1255539034 6.197637e-01 0.1528159549
1368 P49257 LMAN1 0.3622248162 1.360145e-01 0.1633911931
1369 O75436 VPS26A -0.4446357587 2.194143e-02 0.2470100373
1370 P49821 NDUFV1 -0.1739867927 3.974064e-01 0.1445148178
1371 P60033 CD81 0.2138264116 1.873557e-01 0.2014163689
1372 P84095 RHOG 0.0130944774 9.440755e-01 -0.2018248668
1373 Q15836 VAMP3 -0.4501115145 8.462332e-03 -0.1669144692
1374 P42765 ACAA2 -0.0097654094 9.531766e-01 0.1658497680
1375 O95777 LSM8 -0.1232393564 5.871844e-01 -0.3627875751
1376 Q9UG63 ABCF2 -0.1793084711 2.923517e-01 -0.3198460718
1377 P23471 PTPRZ1 -1.8380208226 4.134054e-02 0.3306605987
1378 Q9BV35 SLC25A23 0.4919305499 1.840405e-01 0.1495701720
1379 O43909 EXTL3 -0.2417633874 2.016974e-01 -0.2588645770
1380 Q8TBC4 UBA3 -0.4470115703 1.081952e-02 0.2740878873
1381 P11142 HSPA8 -0.1120909167 5.556990e-01 0.1375474911
1382 P30048 PRDX3 0.4574038642 3.688970e-02 0.1356290773
1383 Q9H173 SIL1 -0.0528623030 8.260484e-01 -0.4179321655
1384 Q86VP6 CAND1 -0.0397175883 8.171965e-01 0.1834502649
1385 Q6ZNB6 NFXL1 0.2699386779 1.299681e-01 -0.3242395030
1386 P51610 HCFC1 0.0139026053 9.560853e-01 0.1934506828
1387 O96019 ACTL6A 0.3714181468 9.080026e-02 -0.1489503500
1388 Q9BZZ5 API5 -0.0899678184 5.555046e-01 -0.1696430939
1389 Q8N983 MRPL43 0.2037530918 2.558748e-01 -0.3774227433
1390 Q96GD0 PDXP 0.7840934441 4.605458e-03 0.7947308803
1391 P55735 SEC13 0.5422210806 1.305824e-03 0.1385605348
1392 Q96PE7 MCEE -0.0298643257 9.399329e-01 0.3123543318
1393 P19021 PAM 0.0596644561 8.344395e-01 -0.2202004135
1394 Q9NPH3 IL1RAP -1.0472359928 5.965804e-04 0.3338440517
1395 Q08J23 NSUN2 -0.1666072327 3.454471e-01 -0.1676191426
1396 Q08623 PUDP -0.3650137374 4.738124e-02 0.7666161069
1397 Q13439 GOLGA4 0.0871495074 5.805587e-01 0.2066317185
1398 Q5JR59 MTUS2 1.3856369471 1.123932e-03 0.3573558785
1399 P07942 LAMB1 0.7587264630 1.699551e-02 -0.2046992466
1400 O43491 EPB41L2 0.4950260111 2.675653e-01 0.3757262075
1401 Q6YN16 HSDL2 -0.6335113257 8.462332e-03 0.1525930061
1402 O95793 STAU1 -0.3752495163 3.461841e-02 -0.1779168350
1403 P54725 RAD23A 0.7934363991 1.194638e-04 -0.2013385424
1404 P28482 MAPK1 -0.3116937867 1.910829e-02 0.2054883472
1405 Q10570 CPSF1 0.1310133571 3.689465e-01 -0.2038856728
1406 Q9UK45 LSM7 -0.0900907482 7.426571e-01 -0.2177406623
1407 Q9BXJ8 TMEM120A 0.2358585935 5.965741e-02 0.4556479812
1408 Q9NX47 MARCHF5 -0.1759985128 1.230138e-01 -0.2048633444
1409 Q9BYW2 SETD2 0.3276360164 3.156658e-02 -0.2219309686
1410 P06737 PYGL -1.2697589330 2.164541e-09 0.3214946498
1411 P20336 RAB3A 0.9973077526 1.337983e-02 -0.5551680429
1412 Q6UX07 DHRS13 0.1807359059 6.515495e-01 -0.3932751306
1413 Q8IVF2 AHNAK2 -0.8311904374 3.302512e-02 -0.3026347170
1414 Q9UDX5 MTFP1 0.6562423049 1.186882e-01 -0.2319046639
1415 Q9H3G5 CPVL 0.1390151955 6.623457e-01 0.1249858773
1416 Q9UEY8 ADD3 0.6324864962 1.181397e-02 0.1931230260
1417 P52209 PGD -1.1149314800 2.243988e-07 0.2922302106
1418 P53597 SUCLG1 0.6181336384 1.993105e-02 0.1912003732
1419 A4UGR9 XIRP2 2.4905258168 1.119086e-01 -0.2269443773
1420 O43854 EDIL3 0.2860416366 7.718964e-01 -0.3948449302
1421 Q969H8 MYDGF 0.0387146865 9.418177e-01 0.1947359574
1422 O76024 WFS1 0.0547337907 8.089624e-01 -0.1828645648
1423 Q9BSD7 NTPCR -0.6238779689 1.930237e-03 0.1944969932
1424 P31930 UQCRC1 0.2519176584 1.997361e-01 0.1739632470
1425 Q6NUK1 SLC25A24 0.9003719479 4.596853e-06 0.1706370371
1426 P14868 DARS1 0.5050206219 9.628551e-02 0.1276870681
1427 Q9Y2Q3 GSTK1 0.2043138029 3.395401e-01 -0.2347226597
1428 Q99829 CPNE1 0.0429119650 8.451320e-01 0.4119754421
1429 O43181 NDUFS4 0.7052030058 7.656405e-03 0.1399504432
1430 P40937 RFC5 1.3275675619 1.047054e-06 -0.3457421561
1431 Q49A88 CCDC14 0.8631370897 2.526654e-04 -0.3769303003
1432 P48444 ARCN1 -0.3134527240 2.437644e-01 0.1787571873
1433 A6NDG6 PGP 0.8445219568 5.148613e-03 0.9020558768
1434 Q86Y39 NDUFA11 -0.1473201374 7.231248e-01 0.1442489499
1435 P68133 ACTA1 1.9681486393 1.453014e-01 0.4065555948
1436 Q5BJD5 TMEM41B 0.2687774711 1.039667e-01 -0.1146413565
1437 O95167 NDUFA3 0.1116812849 7.479148e-01 0.3819258261
1438 Q9Y277 VDAC3 0.2182083325 4.139644e-01 0.1423087293
1439 Q03252 LMNB2 1.5270141096 5.232113e-08 0.1300332666
1440 Q9BQ52 ELAC2 0.4683545774 1.747223e-03 -0.1714179530
1441 Q8IYB8 SUPV3L1 -0.1791004805 8.290764e-02 0.1695546343
1442 P22830 FECH -0.0814246543 7.846933e-01 0.1696781285
1443 Q96HY6 DDRGK1 0.6580762653 2.821087e-03 -0.4241305396
1444 Q99807 COQ7 -0.0106316375 9.607669e-01 -0.3499586745
1445 Q6ZXV5 TMTC3 -0.5770581993 2.636265e-02 -0.1219694750
1446 P26440 IVD 0.2984579133 3.460452e-02 0.1345680756
1447 P30405 PPIF -0.2204973612 2.591195e-01 0.1722444477
1448 Q8N490 PNKD 0.8205032256 1.784634e-04 0.2143259695
1449 Q8WUY1 THEM6 2.8374047428 3.205397e-10 -0.2366917099
1450 P56545 CTBP2 -0.2272613345 1.530905e-01 -0.1586315023
1451 Q9NNW7 TXNRD2 0.1932756669 6.509988e-01 0.2203412051
1452 P61163 ACTR1A 0.0264030234 8.576817e-01 0.1568730927
1453 Q5ZPR3 CD276 -0.7487156798 2.005037e-02 0.5294558186
1454 O43674 NDUFB5 0.1820378276 5.484705e-01 -0.2400599582
1455 P49755 TMED10 0.2785278679 8.919661e-02 0.2606131025
1456 Q9H7F0 ATP13A3 0.3887749942 1.328384e-01 -0.2814472256
1457 P52594 AGFG1 -0.3955555234 3.642568e-03 0.2251423360
1458 P11586 MTHFD1 1.4447541588 8.308105e-09 0.4097285533
1459 P17987 TCP1 0.2282805566 1.236860e-01 0.1599648738
1460 P09960 LTA4H -0.5960658362 1.122294e-05 0.3374283381
1461 Q96GQ5 RUSF1 0.2195671986 2.168049e-01 -0.2735823428
1462 Q14524 SCN5A 2.0508096541 1.805189e-11 -0.1783913409
1463 Q9HCC0 MCCC2 0.2788300967 4.161078e-02 0.1479036002
1464 P41247 PNPLA4 -0.3265835033 2.710520e-01 -0.5672004033
1465 Q08722 CD47 0.2526191664 2.082809e-01 0.1833158546
1466 Q13393 PLD1 0.3617911813 6.623782e-02 -0.3781307178
1467 Q10567 AP1B1 -0.2948061186 3.248651e-02 0.1634320972
1468 Q13464 ROCK1 0.1933406902 3.032811e-01 0.5412345970
1469 P30101 PDIA3 0.0086654019 9.829745e-01 0.1539244082
1470 Q15428 SF3A2 0.4164544855 1.497359e-02 -0.4168327023
1471 Q9Y696 CLIC4 0.5348426386 9.324176e-02 -0.2644762835
1472 Q969M3 YIPF5 -0.2321594888 1.445567e-01 -0.3183726759
1473 P53680 AP2S1 0.1359370191 5.511424e-01 -0.1748212375
1474 O95571 ETHE1 0.0812171329 7.829920e-01 0.2042071532
1475 O15258 RER1 -0.2121602638 1.700926e-01 0.2946458440
1476 O60231 DHX16 -0.0501905240 8.435382e-01 -0.3615133076
1477 Q96SN8 CDK5RAP2 0.5107350974 5.425311e-03 -0.3990717083
1478 Q9P2R7 SUCLA2 -0.0874001242 7.094227e-01 0.1511876257
1479 P80404 ABAT 1.4912747864 1.197906e-04 0.2589337745
1480 P37802 TAGLN2 -0.1809339725 8.384457e-01 0.4247578463
1481 Q92736 RYR2 1.4501324771 1.612760e-03 0.1583752804
1482 Q9BWF3 RBM4 -0.4178381394 3.868243e-04 -0.1708557213
1483 P35268 RPL22 0.0289640361 8.893281e-01 -0.1314736851
1484 P08240 SRPRA 0.3773784764 2.388333e-02 -0.1640100525
1485 O94901 SUN1 0.3554365020 2.368120e-02 0.1897139185
1486 Q96E11 MRRF 0.5421217999 1.662836e-04 -0.3547290681
1487 P35237 SERPINB6 0.0991143007 7.020432e-01 0.2123020967
1488 O00217 NDUFS8 0.6085900117 3.558259e-03 -0.1497285352
1489 Q9BX79 STRA6 0.5684384079 1.020726e-01 0.6251707481
1490 P30086 PEBP1 -0.0420223739 7.966408e-01 0.1829728813
1491 Q9Y3B7 MRPL11 0.2162217405 2.496476e-01 -0.1826969056
1492 Q13162 PRDX4 0.0255711551 9.130904e-01 0.1387678869
1493 Q9Y3I0 RTCB -0.0168064298 8.991323e-01 0.1354217771
1494 P19367 HK1 0.1868705214 2.115534e-01 0.1356042458
1495 Q8WTW3 COG1 -0.7135336175 3.992086e-05 -0.2163136486
1496 Q6IN85 PPP4R3A -0.7114568332 2.414227e-07 -0.2935051522
1497 Q15388 TOMM20 0.4729087275 1.634914e-05 -0.1997517294
1498 O43143 DHX15 0.4069308591 1.662068e-02 -0.1478656322
1499 P20042 EIF2S2 -0.2851062205 3.121713e-02 -0.1697867618
1500 P30046 DDT 0.0677336758 8.526218e-01 0.2232652366
1501 Q06210 GFPT1 0.4511681733 2.975976e-03 0.3592277349
1502 P61916 NPC2 -0.0996592680 6.254355e-01 0.1578093580
1503 Q96G23 CERS2 -0.0215797878 9.420915e-01 -0.2733087334
1504 P51531 SMARCA2 -0.0587417454 8.036622e-01 -0.2662306396
1505 P45379 TNNT2 0.7515131141 3.732140e-02 -0.4203079802
1506 Q6UW56 ATRAID 0.1256591601 4.701730e-01 1.1206318431
1507 Q96AC1 FERMT2 0.3692665404 1.501799e-01 0.2279536937
1508 O00622 CCN1 0.1272558401 8.353794e-01 -0.5884289392
1509 Q86VI1 EXOC3L1 -1.2006507244 1.226800e-06 -0.1922496341
1510 P14550 AKR1A1 -0.3938676776 1.021968e-02 0.2049176888
1511 Q5JVF3 PCID2 -0.3185466867 2.395503e-02 -0.4192457029
1512 Q9Y6Y8 SEC23IP 0.4037452180 5.279361e-04 0.2575344642
1513 O94979 SEC31A -0.4285633093 4.107315e-02 0.1403036475
1514 O15260 SURF4 -0.1275905789 5.698260e-01 0.3828737024
1515 Q6UW63 POGLUT2 -0.0636772305 8.703472e-01 0.3718952595
1516 Q8IWA6 CCDC60 -4.6017447645 4.289264e-10 -1.1748616520
1517 P30044 PRDX5 -0.0877710188 7.138991e-01 -0.1875597915
1518 P02511 CRYAB 0.0846854044 9.036887e-01 -0.2649749515
1519 Q92947 GCDH 0.2600129387 6.522259e-02 0.1404295768
1520 P63010 AP2B1 -0.1904118329 2.351845e-01 0.1265583997
1521 Q9NQZ5 STARD7 0.9291376490 1.107584e-07 0.2768460770
1522 Q9Y5L0 TNPO3 0.1283966114 4.922021e-01 0.4084989557
1523 P23634 ATP2B4 0.7035487050 2.629039e-03 0.1578526585
1524 Q9Y2Z0 SUGT1 0.0500726171 7.965814e-01 0.2626134284
1525 Q01469 FABP5 -1.1102514606 1.147383e-04 0.3199039862
1526 Q8N5M9 JAGN1 -0.1004521192 4.678910e-01 0.4211300832
1527 P53634 CTSC 1.0805573904 4.738244e-04 0.1530751873
1528 Q9BW27 NUP85 0.4593943340 3.535362e-03 -0.3112330991
1529 P42345 MTOR 0.2528124985 1.059118e-01 0.1964298987
1530 P02461 COL3A1 0.4045696891 6.993849e-01 -0.5581871743
1531 Q86TV6 TTC7B 0.6734697249 7.133974e-04 0.3567904027
1532 Q96HN2 AHCYL2 0.0442939064 9.065459e-01 -0.3380675936
1533 Q9ULX6 AKAP8L -0.5915065004 1.177978e-03 -0.2131864988
1534 O00192 ARVCF -0.9811165019 6.272316e-04 0.2773729555
1535 P31153 MAT2A -0.0861283860 6.566185e-01 -0.2944864528
1536 Q8IY17 PNPLA6 0.6232170572 2.038740e-03 0.3219863805
1537 Q9NR28 DIABLO -0.1294132569 3.995054e-01 0.2193858814
1538 Q71UM5 RPS27L -1.2890953658 1.295235e-06 -0.2213285426
1539 Q13724 MOGS 0.3327314626 1.800319e-01 0.2510442243
1540 Q13443 ADAM9 0.0573339019 9.190308e-01 0.3483369572
1541 P00568 AK1 -0.5484053712 9.717693e-03 0.2295284048
1542 Q9NUT2 ABCB8 0.1839095756 3.858076e-01 0.2707294449
1543 Q13889 GTF2H3 0.0857315799 5.819400e-01 -0.3737205849
1544 Q14254 FLOT2 0.1682379007 2.402563e-01 0.1844702112
1545 Q14204 DYNC1H1 -0.4361423594 4.284663e-02 0.1747237411
1546 P42785 PRCP 0.4586363716 6.983123e-02 0.1266610913
1547 O15498 YKT6 0.0774974883 6.761154e-01 0.1263343407
1548 O14662 STX16 -0.7371742180 5.786007e-06 0.2403507390
1549 Q8N684 CPSF7 -0.1302151618 3.789783e-01 -0.1642694784
1550 Q9UBY9 HSPB7 1.7573820921 4.612292e-04 0.1989696848
1551 Q6ZVM7 TOM1L2 -0.0449998063 8.627737e-01 -0.2152424473
1552 Q14642 INPP5A 0.0321604204 8.924107e-01 -0.2024959410
1553 Q6NXT4 SLC30A6 0.1463722928 2.982599e-01 -0.1869593310
1554 A1A4S6 ARHGAP10 -0.8139164783 9.576317e-05 1.2569154842
1555 Q9UPN3 MACF1 0.1208039512 7.315256e-01 -0.1655102239
1556 Q13435 SF3B2 -0.2478010756 6.256746e-02 -0.1225704779
1557 Q9Y4J8 DTNA 0.9401594234 3.984492e-03 -0.1627755026
1558 Q96ST3 SIN3A 0.2346134317 3.711127e-01 0.2459319442
1559 Q8NFQ8 TOR1AIP2 -0.2509775227 7.310169e-02 -0.2140915439
1560 P58107 EPPK1 -1.5092236644 8.093815e-03 0.4440944221
1561 Q9Y3A6 TMED5 0.5103033760 2.647971e-03 0.2499658609
1562 Q9NW13 RBM28 1.0108039937 6.077584e-09 -0.6322504970
1563 Q5MNZ6 WDR45B -0.1011004976 3.426630e-01 0.2034250198
1564 A8MXV4 NUDT19 0.7973983737 3.571356e-02 -0.4131167536
1565 Q15370 ELOB -0.2393897686 3.343181e-01 -0.2629063161
1566 Q5THK1 PRR14L -0.5239246509 2.021663e-02 -0.1619819506
1567 P31939 ATIC 0.6337753900 2.000627e-09 0.2781767762
1568 Q6QEF8 CORO6 0.0562593217 9.144368e-01 0.1717452486
1569 Q8IWB1 ITPRIP 0.7037180359 1.527445e-02 0.2640393362
1570 O75179 ANKRD17 0.1376580118 3.816490e-01 -0.1393212043
1571 O00165 HAX1 0.8693445690 1.393538e-03 -0.1896560845
1572 Q96GE9 DMAC1 0.1861130148 6.435786e-01 -0.4584078011
1573 Q9HD20 ATP13A1 -0.5854556919 9.972490e-03 -0.1919268814
1574 Q96M27 PRRC1 0.4152923823 1.291836e-02 0.1731613968
1575 O75843 AP1G2 -0.3715774646 1.451499e-01 0.2032373336
1576 Q9P0J0 NDUFA13 -0.1316382177 6.646525e-01 -0.1482501119
1577 Q14247 CTTN -0.3246142023 2.976993e-01 0.2038126527
1578 Q9HA77 CARS2 0.3897356747 3.252390e-02 0.1418524862
1579 Q92542 NCSTN -0.2322432808 3.148938e-01 0.2264951318
1580 Q16401 PSMD5 -0.1060433484 7.880189e-01 0.7614004148
1581 P11166 SLC2A1 0.2690211584 5.706415e-01 -0.3401007616
1582 P48735 IDH2 0.0025445494 9.946207e-01 0.1456566581
1583 Q9H488 POFUT1 0.4356741765 2.200447e-02 0.1394492596
1584 Q9P265 DIP2B 0.2760783862 1.736875e-01 0.1794882687
1585 Q6ZWT7 MBOAT2 0.1662557261 2.266774e-01 -0.3284056844
1586 P04792 HSPB1 0.2672958343 4.574401e-01 0.2102243181
1587 Q9BQP7 MGME1 -0.6384503973 6.115062e-06 -0.2150802840
1588 P61019 RAB2A 0.1966666795 1.480561e-01 -0.1386995442
1589 Q9Y385 UBE2J1 0.3700648637 2.208082e-01 -0.2023316616
1590 O94919 ENDOD1 -1.7729211535 6.177175e-07 0.1846416190
1591 P35625 TIMP3 0.8462492444 1.375839e-01 -0.6193118089
1592 Q9UIQ6 LNPEP 0.2024059429 4.499877e-01 0.1698605945
1593 Q9H1B7 IRF2BPL -0.5750532066 7.417813e-04 -0.2046320465
1594 Q9Y3F4 STRAP -0.1374830759 1.356946e-01 -0.3711372142
1595 Q6ZVF9 GPRIN3 2.3992186463 4.465813e-04 -0.2456349172
1596 Q08AM6 VAC14 0.0394764028 7.755739e-01 0.4518592849
1597 Q9UBB4 ATXN10 -0.0507787396 7.096562e-01 0.3456520334
1598 P21964 COMT 0.0006917953 9.988233e-01 -0.3590790930
1599 Q32P28 P3H1 -0.7234915878 2.083102e-01 0.3567368899
1600 Q8IUG5 MYO18B 0.7194227033 2.015646e-03 -0.1424573779
1601 P45973 CBX5 1.5111264349 5.550083e-12 0.2489579868
1602 P50570 DNM2 0.0695868180 6.585118e-01 0.1291995546
1603 P48382 RFX5 0.1321931302 3.719748e-01 0.1798371745
1604 Q9HB71 CACYBP 0.6176745477 4.182411e-03 0.1435524358
1605 Q9NYL2 MAP3K20 0.5086511034 1.182328e-01 0.2512525141
1606 Q96AY3 FKBP10 0.4467243427 1.113112e-01 0.2029690883
1607 Q15526 SURF1 -0.8715337838 9.907168e-06 0.2087570688
1608 P56192 MARS1 0.4166693182 1.134044e-03 0.1177502284
1609 P16278 GLB1 0.1732844191 4.753941e-01 0.1844768679
1610 Q14697 GANAB -0.1566748974 6.054961e-01 0.1132188809
1611 Q9BZ29 DOCK9 0.0382882737 9.237096e-01 1.0994459896
1612 Q96F07 CYFIP2 -1.1786946446 8.220763e-05 0.3947110352
1613 O43396 TXNL1 -0.1761030215 1.065178e-01 0.2121736850
1614 Q9Y4K0 LOXL2 -0.3363789099 1.677229e-01 0.3820621333
1615 Q9UIJ7 AK3 -0.6608146256 4.135304e-05 -0.1892167283
1616 P09669 COX6C -0.1894286858 6.067403e-01 -0.3073166158
1617 P25788 PSMA3 -0.2976410304 9.860888e-02 0.1358267045
1618 O75380 NDUFS6 0.2241556251 4.170884e-01 -0.1519854196
1619 Q12797 ASPH 0.7468930503 2.666929e-02 0.2677206428
1620 O00487 PSMD14 0.6560064802 2.822175e-04 -0.1276894010
1621 P51858 HDGF 1.0238409074 7.757876e-11 0.2814176576
1622 P98179 RBM3 0.3710102267 2.595213e-01 -0.1994485307
1623 Q96EY4 TMA16 -0.2307161639 2.740189e-01 -0.3853440432
1624 P56937 HSD17B7 -1.0319086106 5.613777e-06 0.3108440907
1625 Q5JTV8 TOR1AIP1 0.5452031019 4.412361e-04 -0.4057918444
1626 Q2KHT3 CLEC16A -0.7256892280 5.099687e-04 0.1885129287
1627 Q9HC77 CENPJ 1.6345556701 4.937728e-08 -0.1489839924
1628 Q9H2U2 PPA2 0.5632870030 1.752156e-02 0.1786945349
1629 P30519 HMOX2 -0.5668095686 1.666777e-03 -0.2172233972
1630 P51689 ARSD -0.1068071500 5.108484e-01 0.2628487810
1631 Q5JS37 NHLRC3 1.4873507233 2.630120e-10 0.1329728029
1632 P31431 SDC4 -1.1900302931 9.106766e-07 0.3291979286
1633 Q7Z7K6 CENPV 1.0392761420 3.544615e-03 0.2808150998
1634 P62314 SNRPD1 0.7718443987 7.409111e-04 -0.2341272132
1635 O95447 LCA5L -0.0860953128 8.787568e-01 0.5482526245
1636 P10809 HSPD1 0.5156892316 8.698080e-03 0.1505143852
1637 O95139 NDUFB6 0.1670298208 5.954926e-01 -0.1543210621
1638 Q7L576 CYFIP1 -0.1579722296 7.277515e-01 0.1759483154
1639 Q969T9 WBP2 0.1029774584 5.470422e-01 -0.7229710435
1640 Q15904 ATP6AP1 0.0780591274 7.842824e-01 0.2328552920
1641 P56199 ITGA1 -0.7914205536 2.987471e-01 0.3363279060
1642 A6ZKI3 RTL8C 0.2674308784 1.598083e-01 0.3862971555
1643 P00505 GOT2 0.6650423493 4.266416e-04 0.1505975124
1644 P22626 HNRNPA2B1 0.7619731970 5.774953e-06 -0.1259800264
1645 Q13425 SNTB2 -0.9985660031 3.115714e-04 0.1547902954
1646 P50552 VASP 0.5519423779 2.128793e-02 0.2036752498
1647 Q96J88 EPSTI1 -1.1095042439 1.835069e-01 0.7971485090
1648 P42126 ECI1 1.0185534813 2.020110e-03 0.1516371828
1649 Q9HB40 SCPEP1 0.0897454152 8.330211e-01 -0.6404741507
1650 Q9HCL3 ZFP14 0.6803202071 6.676085e-03 0.5196648792
1651 Q96AX1 VPS33A -0.2167579337 1.449379e-01 -0.2664545546
1652 Q15165 PON2 0.2774137877 2.959670e-01 0.1786214258
1653 Q9NRF8 CTPS2 1.3238802508 1.837109e-16 0.1428261347
1654 Q9H9B4 SFXN1 0.2196153140 1.419957e-01 0.1536044680
1655 O43815 STRN 0.1048373712 7.259133e-01 -0.1134483301
1656 Q3KQZ1 SLC25A35 1.1664195057 4.317272e-07 0.6135109749
1657 Q9UJZ1 STOML2 0.0368973879 8.171965e-01 -0.2476196549
1658 Q99996 AKAP9 0.1948005093 4.232226e-01 -0.2443833248
1659 P18669 PGAM1 0.2028517603 3.849766e-01 0.2679061725
1660 Q13630 GFUS -0.4030045181 4.907970e-03 0.2119346831
1661 P12235 SLC25A4 1.3059959512 1.289144e-03 0.1232137170
1662 Q14766 LTBP1 0.9078201672 7.718248e-05 -0.3149054734
1663 P35579 MYH9 0.3064838495 6.147760e-01 0.2208384406
1664 Q9UGL1 KDM5B -0.5425211142 2.870172e-03 0.1939024144
1665 P07814 EPRS1 1.3991085717 6.673332e-11 0.1227043825
1666 Q9Y6K9 IKBKG -0.6062737695 2.527446e-06 0.5400156682
1667 P09972 ALDOC 1.9503624199 6.912356e-04 0.3560863340
1668 Q9Y265 RUVBL1 0.3032835184 4.325777e-02 -0.1487258718
1669 Q86TC9 MYPN 0.8167511169 1.148090e-01 0.2220605490
1670 O75051 PLXNA2 -0.6176603259 8.652638e-02 -0.1799037193
1671 P30533 LRPAP1 -1.1306558297 4.057262e-07 0.1967298835
1672 Q8NC56 LEMD2 -0.0046183220 9.824619e-01 -0.1402372840
1673 P23368 ME2 0.1709489761 4.827411e-01 0.1946472071
1674 Q9NRL2 BAZ1A -1.0786331149 9.534784e-04 0.2543600134
1675 Q13952 NFYC -0.2389293218 1.725348e-01 0.2361853690
1676 Q9BW92 TARS2 1.4429571358 2.152874e-08 -0.1210626053
1677 Q9BXP5 SRRT 0.5537577167 2.897458e-04 -0.1177464463
1678 O14980 XPO1 -0.1371049070 3.824226e-01 -0.1476165330
1679 Q04760 GLO1 0.2932020001 8.689470e-02 0.2606785320
1680 Q15436 SEC23A 0.6805391443 8.675127e-04 0.1399809919
1681 P04075 ALDOA 0.0437099893 9.203675e-01 0.1865845426
1682 Q9Y3L5 RAP2C -0.0492094416 7.889271e-01 0.1493853231
1683 Q9UBT2 UBA2 0.0243869844 9.111757e-01 -0.2555945521
1684 Q99943 AGPAT1 0.0330194316 8.025897e-01 0.2520398057
1685 Q96Q11 TRNT1 -0.0958705602 7.644507e-01 0.2996196471
1686 Q8IXS6 PALM2AKAP2 1.5083646100 2.554631e-04 0.1479163298
1687 Q6NUQ1 RINT1 0.2479042651 1.416423e-01 0.2057463484
1688 O14908 GIPC1 0.7507979068 1.175732e-06 0.2825310123
1689 P55011 SLC12A2 -0.1971249744 2.819238e-01 0.2640968158
1690 Q8N5B7 CERS5 -0.2107396217 6.479203e-01 0.1977423568
1691 Q9H936 SLC25A22 0.3061353463 4.664245e-01 0.3122123183
1692 Q9Y2J2 EPB41L3 0.0713132272 7.398659e-01 0.1232028947
1693 O96008 TOMM40 0.9213332719 7.199240e-09 0.1615035994
1694 Q06481 APLP2 -0.5376891342 4.303612e-03 0.1381457962
1695 O43681 GET3 -0.2007565862 1.422552e-01 0.1082411643
1696 P00742 F10 0.4890441414 1.182328e-01 -0.3288842935
1697 P04179 SOD2 0.2781151469 3.260615e-01 0.1236782127
1698 P12829 MYL4 0.3812090277 4.623616e-01 -0.2252215300
1699 O75955 FLOT1 -0.5223567371 3.467202e-02 0.1223331444
1700 O95816 BAG2 0.5760476370 6.416839e-03 -0.2449752601
1701 O95425 SVIL 0.2849438519 2.677598e-01 -0.1378927305
1702 P12883 MYH7 3.2002356649 2.374922e-06 0.1878757736
1703 Q9Y624 F11R -0.6698592368 7.290407e-02 -0.2704909154
1704 P16615 ATP2A2 1.3950531945 2.805068e-06 0.1065416788
1705 Q9UI12 ATP6V1H -0.5286497070 1.907817e-04 -0.2231393848
1706 Q8NCN5 PDPR 0.1245631168 6.835264e-01 0.1686627684
1707 P60174 TPI1 0.5239464535 2.235432e-01 0.2273542608
1708 P54802 NAGLU 0.1088198260 7.137069e-01 0.1815756870
1709 Q9NVH1 DNAJC11 0.2327038427 1.482114e-01 0.1263945529
1710 P33240 CSTF2 0.7411593546 1.436905e-04 -0.2019461981
1711 Q4KMQ2 ANO6 0.0869262523 5.858591e-01 0.1211254836
1712 P18754 RCC1 0.1984993716 5.687145e-01 0.1356243660
1713 P35612 ADD2 1.0966591721 3.731146e-02 0.3021874813
1714 P02144 MB 0.3409033194 6.394701e-01 -0.3342276775
1715 P45877 PPIC 0.1403106041 4.195817e-01 0.1508902709
1716 P14209 CD99 0.1339613296 5.522434e-01 0.8137557802
1717 Q13445 TMED1 0.7710553637 1.681322e-03 0.1385010702
1718 Q66K74 MAP1S -0.4471975949 3.154724e-03 0.1850543583
1719 Q6P587 FAHD1 -0.3824098055 1.904442e-03 -0.1377394502
1720 O60684 KPNA6 -0.3695764463 9.222340e-03 -0.4215543822
1721 Q9HAC7 SUGCT -1.0793388523 1.108564e-08 0.2098903285
1722 P60900 PSMA6 -0.3814378167 7.625722e-02 0.1124389846
1723 P10916 MYL2 0.7205282380 4.278901e-01 -0.3579173999
1724 P05091 ALDH2 -0.1774247001 3.132016e-01 0.1740427263
1725 P00558 PGK1 -0.1207563594 8.357532e-01 0.2193683417
1726 Q15629 TRAM1 0.4070980955 1.720433e-02 -0.1422236499
1727 P06730 EIF4E 0.0441172842 8.268671e-01 -0.1238886474
1728 Q96CW1 AP2M1 -0.1318980132 3.473382e-01 0.1100212785
1729 Q9H269 VPS16 -0.2413084532 9.153004e-02 -0.5201741173
1730 Q13427 PPIG -0.0262678567 9.151958e-01 -0.1613273299
1731 Q96CB9 NSUN4 0.9415160531 4.973727e-07 -0.1687411465
1732 Q5NDL2 EOGT 0.2822393347 4.797973e-02 -0.2654249140
1733 Q13564 NAE1 0.8003449594 1.029047e-08 0.4371709366
1734 Q9H223 EHD4 0.3609409286 1.149628e-01 0.3161051930
1735 P19823 ITIH2 -0.6444373128 7.828187e-01 0.2641095507
1736 Q96EC8 YIPF6 -0.1747482031 9.934305e-02 -0.2964064156
1737 O00567 NOP56 -0.2540248234 2.095424e-01 0.2449748418
1738 O95070 YIF1A 0.2854400715 6.551948e-02 -0.2071578184
1739 Q04656 ATP7A 0.3419538655 1.501427e-01 -0.3047021024
1740 Q96PE3 INPP4A -0.4470815633 1.016122e-04 0.1812734486
1741 O43813 LANCL1 0.5969387543 2.895836e-04 0.2028367121
1742 P55290 CDH13 0.1818396046 8.314755e-01 0.7374886596
1743 Q05086 UBE3A -0.5021721131 4.268154e-03 -0.3042980713
1744 P07339 CTSD 0.1030770325 7.056427e-01 0.1604490806
1745 P08238 HSP90AB1 0.0952591610 6.220550e-01 0.1199150173
1746 Q9Y5K8 ATP6V1D -0.4597088451 3.702169e-03 -0.1794847801
1747 P53621 COPA 0.0445635167 7.922981e-01 0.1198959270
1748 Q13433 SLC39A6 -0.3532648783 3.930349e-01 -0.3647429847
1749 Q9HDC9 APMAP -0.2734291892 4.693337e-01 0.1669020284
1750 P46977 STT3A 0.8200456788 1.230085e-02 0.2287939484
1751 Q9Y5K5 UCHL5 0.1053317596 5.846743e-01 0.1856459077
1752 Q9NZA1 CLIC5 0.3906525004 1.430895e-01 -0.2037149376
1753 Q6P4A7 SFXN4 1.2984385374 1.491799e-05 0.1680862376
1754 Q9BUN8 DERL1 0.2268389334 5.507804e-02 -0.4786288291
1755 Q6UXV4 APOOL -0.0735997758 6.890104e-01 0.1936065215
1756 Q8NB25 FAM184A -1.1543964258 1.603258e-03 0.2431381295
1757 P31948 STIP1 0.1941636203 2.222603e-01 0.1197831916
1758 Q8NI27 THOC2 0.3197363656 6.150198e-02 -0.1928366990
1759 P63104 YWHAZ -0.6623936141 1.156325e-04 -0.2896384659
1760 Q9BSF4 TIMM29 -0.5766783958 1.417637e-05 -0.1847857949
1761 P08590 MYL3 0.6491676322 2.020188e-01 -0.2268731958
1762 P48739 PITPNB -0.1627901348 3.913320e-01 0.3351063565
1763 Q01459 CTBS -0.6017499116 1.842871e-02 0.7262850014
1764 Q9H3K2 GHITM -0.5241435734 1.507280e-03 0.1193456952
1765 Q9GZY8 MFF 0.2661618043 2.479116e-02 -0.1856868209
1766 P49792 RANBP2 -0.2979140036 8.998002e-02 0.1411615606
1767 Q8WUD1 RAB2B 0.0272863409 8.351565e-01 0.1435746546
1768 Q12765 SCRN1 0.6442595169 1.342872e-02 -0.4121759213
1769 Q8NB12 SMYD1 1.9347224732 2.672598e-05 0.1950751068
1770 P0C7P0 CISD3 1.8293318918 2.316466e-10 -0.1774755759
1771 O15254 ACOX3 1.4282634458 3.580569e-06 -0.2440525252
1772 P36542 ATP5F1C 1.1684969164 1.389818e-03 0.1290881568
1773 P19440 GGT1 0.1182688532 8.687663e-01 -0.2845034110
1774 Q92508 PIEZO1 0.6087620640 4.257620e-02 0.2868523980
1775 O00232 PSMD12 -0.2712867753 3.982575e-02 -0.1521050477
1776 Q15155 NOMO1 0.1704716095 4.735078e-01 0.1508234778
1777 Q9UHD8 SEPTIN9 0.4755562779 3.322623e-03 0.2021339246
1778 Q5JPE7 NOMO2 0.2079791567 4.531615e-01 0.1502564030
1779 O75879 GATB 0.2279772762 1.554719e-01 0.2424868192
1780 Q9Y490 TLN1 0.3420736536 8.924860e-02 0.1045821854
1781 Q96KG9 SCYL1 -0.2893014229 3.637259e-02 -0.5027216185
1782 Q13505 MTX1 -0.1467346670 6.199701e-01 -0.1676507132
1783 Q9UJS0 SLC25A13 0.1982585679 6.345327e-02 0.1540476330
1784 Q86TB3 ALPK2 1.1941536798 1.404986e-05 -0.3214679156
1785 Q2M2I8 AAK1 -0.4396088834 1.902638e-02 -0.2352245268
1786 O00468 AGRN -0.8129678401 1.587084e-02 0.2760268696
1787 Q96FW1 OTUB1 -0.4010101437 5.500048e-04 0.5918018898
1788 Q13185 CBX3 0.5065139414 5.001146e-03 -0.5086292319
1789 P68400 CSNK2A1 0.3173211773 1.966664e-02 -0.1264495797
1790 P28331 NDUFS1 0.5373744935 1.844769e-03 0.1013530396
1791 Q9Y263 PLAA 0.2136937563 7.739730e-02 -0.2299422577
1792 P00167 CYB5A 1.6098182159 3.465401e-06 0.1600876037
1793 Q9NVH6 TMLHE 0.6793260045 3.633019e-03 0.1448143904
1794 P20020 ATP2B1 -0.7931718607 4.120125e-04 -0.1459837821
1795 Q9Y4L1 HYOU1 0.0117236366 9.807059e-01 0.1708269618
1796 P26196 DDX6 0.1186047278 5.234808e-01 -0.1106735179
1797 P14923 JUP -0.6364280671 1.506576e-03 -0.1393551959
1798 P25205 MCM3 2.4623633421 1.867494e-13 -0.2332978096
1799 Q9H3N1 TMX1 -0.4253745548 2.912518e-01 0.1911236098
1800 O43759 SYNGR1 0.4904738733 6.795980e-02 0.3656204165
1801 O60271 SPAG9 -0.3933658419 3.835940e-03 0.1855972361
1802 Q96GS4 BORCS6 -0.7090553563 2.163665e-04 -0.5961135139
1803 Q5SRE5 NUP188 0.3092479704 1.453906e-01 -0.3925170994
1804 P42224 STAT1 -2.0579704677 7.148119e-16 0.5855252691
1805 Q92820 GGH 0.4160082923 2.192069e-01 0.1064003350
1806 Q07866 KLC1 0.0718530160 5.387119e-01 0.1318888957
1807 Q16513 PKN2 0.9101622622 6.846336e-05 -0.3903692553
1808 Q9NTI5 PDS5B 0.3685288435 4.091455e-02 -0.1533700029
1809 P23327 HRC 0.5428981226 1.702822e-01 0.2387106959
1810 Q15631 TSN -0.2364457264 5.589455e-02 0.2206874894
1811 Q6P1A2 LPCAT3 -0.3820973402 7.840920e-02 0.2277853536
1812 O00151 PDLIM1 -0.4085455973 1.691772e-01 0.1937722354
1813 Q9UHQ4 BCAP29 1.3692174226 2.169737e-05 0.1988457745
1814 P48729 CSNK1A1 -0.3718222498 3.449183e-04 -0.1098624407
1815 P09211 GSTP1 -1.2398485588 1.562978e-04 0.1386420303
1816 P62136 PPP1CA -0.6013982668 2.374922e-06 -0.1166498631
1817 P50502 ST13 -0.3448671946 6.254709e-02 0.1402020249
1818 Q08257 CRYZ -0.0208235580 9.652077e-01 0.2084939460
1819 Q7L523 RRAGA -0.9521859873 8.455097e-09 0.1059867484
1820 P22061 PCMT1 0.0493894149 7.817566e-01 -0.1379744633
1821 Q32MK0 MYLK3 0.7087779413 6.127695e-02 0.2027328807
1822 Q8NFH4 NUP37 0.1458760466 5.111842e-01 -0.2263056092
1823 O94776 MTA2 -1.2162968176 3.421653e-06 -0.1556871183
1824 Q5SYE7 NHSL1 1.0705508482 3.484130e-04 0.2624877482
1825 Q8N8Q8 COX18 -0.0110891346 9.536399e-01 0.5482295030
1826 P09486 SPARC 0.1568362773 7.691643e-01 -0.3398549778
1827 Q9BRX8 PRXL2A 0.2092975969 4.171057e-01 0.1059117284
1828 Q16778 H2BC21 -1.4495079785 3.380343e-09 0.1865763781
1829 P62191 PSMC1 0.0400134349 7.914979e-01 0.1104266196
1830 P56134 ATP5MF 0.0823190520 7.345604e-01 -0.1175481021
1831 P51553 IDH3G 0.4376905600 6.857067e-03 0.1406275506
1832 Q6UWP7 LCLAT1 1.2097435583 9.233786e-06 -0.1100540659
1833 Q9UKK6 NXT1 0.5846142978 9.009009e-03 0.1996727921
1834 P08174 CD55 -0.8067393884 4.413626e-02 -0.3830711095
1835 P36404 ARL2 0.4760897507 4.029220e-02 0.1497891845
1836 P40123 CAP2 1.1655884901 4.626400e-05 0.2127646086
1837 Q15149 PLEC 0.3224732115 1.896376e-01 0.0989970306
1838 P27338 MAOB -1.3085970453 1.185109e-01 -0.2416044788
1839 P11055 MYH3 0.8343898183 1.790471e-01 -0.3289073428
1840 Q9UMS0 NFU1 -0.1518704934 5.904522e-01 0.5362827661
1841 Q9NZJ6 COQ3 1.1216940835 1.059948e-04 -0.1937537190
1842 P21796 VDAC1 0.1436004662 3.942572e-01 0.1130945858
1843 P06732 CKM 0.6134077660 4.766527e-01 0.2743177664
1844 Q8IXI2 RHOT1 0.8557003235 9.860472e-07 -0.1023378975
1845 Q9UQ80 PA2G4 -0.7709128371 1.855568e-08 0.1674143768
1846 Q9H9G7 AGO3 0.0782431877 6.981589e-01 0.2266581825
1847 P17050 NAGA -0.2319044352 4.672553e-01 0.1456591584
1848 Q9BU23 LMF2 -1.5700660393 3.711224e-08 0.1656514288
1849 O75112 LDB3 2.7434689196 7.381874e-07 0.1573491429
1850 Q6ZP82 CCDC141 1.5360523458 2.019713e-03 -0.1081806014
1851 Q14141 SEPTIN6 0.3494888553 1.890797e-01 0.3007788675
1852 P24666 ACP1 0.1039417074 4.446857e-01 0.1806922599
1853 O00764 PDXK -0.5187015367 1.260691e-02 0.1675754927
1854 O75781 PALM 0.7913553309 2.824205e-06 0.1608435877
1855 O00629 KPNA4 -0.1831928559 1.137567e-01 -0.1624602228
1856 P53999 SUB1 -0.2134022058 2.946914e-01 0.2110096754
1857 Q9BUQ8 DDX23 -0.0831184730 7.359313e-01 -0.1172680589
1858 O43292 GPAA1 -0.4578929246 6.926732e-04 0.1427424435
1859 P07203 GPX1 -2.4590465803 4.844657e-13 0.1554968850
1860 P38117 ETFB 0.5427571027 3.114159e-02 0.1152187935
1861 Q13683 ITGA7 0.2708923890 5.313725e-01 0.1341858302
1862 Q7Z7H8 MRPL10 -0.3603634488 2.478305e-03 -0.2120833022
1863 O75844 ZMPSTE24 0.0888249323 8.347974e-01 0.1786406642
1864 P17858 PFKL -0.0042978206 9.902724e-01 0.2571098478
1865 Q7L0Y3 TRMT10C -0.1881399775 3.640171e-01 0.1291873526
1866 P98172 EFNB1 -1.9085143771 4.814741e-09 -0.3272065357
1867 P38646 HSPA9 0.7979750611 3.230682e-06 0.1168814392
1868 P49411 TUFM -0.3614799938 5.557599e-04 0.1108361099
1869 Q8IXT5 RBM12B 0.5067110236 2.616229e-02 0.1384347078
1870 Q8NCW5 NAXE 0.2580156677 1.217783e-01 -0.1891713554
1871 Q14896 MYBPC3 0.5923821171 1.348475e-01 0.1551579680
1872 Q6PK18 OGFOD3 0.8702332461 4.996088e-08 0.1939043677
1873 Q9NRL3 STRN4 0.3398639974 2.990451e-03 0.1413990622
1874 O75165 DNAJC13 0.7807099953 2.589505e-09 -0.1258222035
1875 Q9UJA5 TRMT6 -0.1525527130 3.176235e-01 -0.1781832359
1876 C9JTQ0 ANKRD63 0.7409783790 5.179543e-01 -0.4181034357
1877 Q9HBH1 PDF 0.4324040400 1.913444e-01 -0.3972969266
1878 P09651 HNRNPA1 0.8402598523 2.681422e-05 -0.1025116264
1879 Q93034 CUL5 0.1618714903 3.406833e-01 -0.1189350733
1880 P54577 YARS1 0.4680289055 8.632363e-03 0.1600657958
1881 O75487 GPC4 -0.9927054445 9.088184e-03 0.3644860585
1882 Q9P2K5 MYEF2 0.5766910513 3.057090e-03 -0.1733205454
1883 P23381 WARS1 0.2262799839 3.925141e-01 -0.3338646105
1884 P78310 CXADR -0.0109802143 9.623291e-01 -0.2296435722
1885 Q13217 DNAJC3 0.6080622664 5.599550e-02 0.2380869581
1886 P04040 CAT 0.6575400108 1.967081e-01 -0.3228400161
1887 Q9UHL4 DPP7 0.3597153229 5.185833e-01 0.1405542089
1888 Q9UGP8 SEC63 0.5837381944 9.973318e-05 0.1356121218
1889 P14854 COX6B1 -0.1059131964 7.451698e-01 -0.2309149387
1890 Q9Y3D3 MRPS16 -0.0287521425 8.917191e-01 -0.2270881915
1891 P61978 HNRNPK 0.1364059191 2.551803e-01 -0.0908786821
1892 P15531 NME1 -0.2613820498 4.497980e-01 0.1964047121
1893 O75323 NIPSNAP2 0.7843169924 1.550574e-02 0.1164590731
1894 P15924 DSP -0.2366972975 3.077717e-01 -0.2221418710
1895 Q9HAB3 SLC52A2 0.3501628861 2.070068e-01 0.1019734385
1896 Q13190 STX5 -0.9383245202 3.310862e-07 -0.1438827917
1897 Q9Y4P3 TBL2 0.9026931871 2.374922e-06 -0.1376909006
1898 Q14651 PLS1 0.2091548574 4.352572e-01 -0.2391865419
1899 Q8TCS8 PNPT1 0.2014867737 3.051769e-01 0.1246305850
1900 Q02978 SLC25A11 0.8197128328 3.226581e-03 0.1253233305
1901 Q16881 TXNRD1 -1.7811172154 8.055294e-05 0.5291243342
1902 O14683 TP53I11 -1.4212290760 1.116181e-03 0.1794061749
1903 Q969X5 ERGIC1 -0.0185468404 9.577110e-01 0.1341115999
1904 Q15833 STXBP2 -0.3229616767 3.022883e-01 -0.2935734855
1905 P10619 CTSA -0.1007956107 6.370888e-01 0.1232787774
1906 P52815 MRPL12 1.2502905930 5.432475e-05 -0.3479027395
1907 Q9Y2H6 FNDC3A -0.1116559628 5.327590e-01 -0.4244074996
1908 P10155 RO60 0.0543694078 8.344448e-01 0.1438558273
1909 P43034 PAFAH1B1 0.1929284581 4.288570e-01 -0.1716659061
1910 P09429 HMGB1 0.4656724164 3.570169e-02 0.1732072375
1911 Q13813 SPTAN1 0.3142588362 3.137613e-01 0.0911141711
1912 O43464 HTRA2 -0.4377286721 9.427037e-05 -0.1555959272
1913 P35613 BSG -0.1443275679 4.754237e-01 0.1463125698
1914 Q8IXM6 NRM 1.6791260262 6.276217e-09 -0.1277078100
1915 Q6VY07 PACS1 -0.2190860038 4.020375e-01 0.2111877176
1916 Q9NR12 PDLIM7 -0.0429888691 9.221062e-01 -0.3509102066
1917 O15078 CEP290 0.6782119363 2.159324e-03 0.4736180211
1918 Q9BRJ7 NUDT16L1 0.3122016247 1.501522e-01 -0.2906977060
1919 Q9BZF9 UACA 0.3040818225 3.810870e-01 0.1587803118
1920 O60825 PFKFB2 -0.6979328827 1.144153e-02 0.2827424002
1921 Q13423 NNT 0.7812013239 6.762288e-03 0.1346303030
1922 Q1KMD3 HNRNPUL2 0.1163294045 4.825500e-01 -0.1327156417
1923 Q15800 MSMO1 0.5468242144 9.635216e-02 -0.1526145948
1924 Q6P1Q0 LETMD1 0.6995173166 6.017717e-05 0.1546073095
1925 P33897 ABCD1 0.6290223935 4.198877e-06 0.1528123888
1926 Q12955 ANK3 -0.0509586450 8.864972e-01 -0.0969674495
1927 P46199 MTIF2 0.1096824103 4.585699e-01 0.1297635336
1928 P23588 EIF4B 0.3770311203 1.557476e-02 0.1195975287
1929 O95622 ADCY5 1.1975133863 3.300409e-05 -0.1419630652
1930 P06733 ENO1 0.5422332635 1.738513e-01 0.1826309791
1931 Q9NTJ4 MAN2C1 0.0033617407 9.870447e-01 0.1393937256
1932 P50454 SERPINH1 0.0839964853 8.162662e-01 0.1471579924
1933 Q96I25 RBM17 0.0296826351 8.189223e-01 -0.2051732977
1934 Q9Y394 DHRS7 -0.3713217263 2.899647e-01 -0.1402833892
1935 O95865 DDAH2 2.1602406748 9.407488e-10 0.1720986788
1936 Q8NFH3 NUP43 0.3934607468 1.650592e-02 0.1091842804
1937 Q86U28 ISCA2 0.7101169214 1.344176e-02 -0.3145349692
1938 O43306 ADCY6 0.1854319436 5.083174e-01 -0.1829436373
1939 Q8IW45 NAXD -0.8358224024 5.485080e-07 0.1620047804
1940 Q9HAB8 PPCS 0.0848111115 6.423964e-01 0.2956679206
1941 Q53H12 AGK 0.9499337765 5.633987e-07 0.1035594132
1942 Q9Y4W2 LAS1L 0.4829859012 4.905683e-02 -0.1389552255
1943 Q96S52 PIGS -0.0010698844 9.955733e-01 0.1635104108
1944 Q96I99 SUCLG2 0.5196720525 6.050381e-02 0.0926078408
1945 P43686 PSMC4 -0.0325124396 7.560025e-01 -0.1469129728
1946 Q7Z6Z7 HUWE1 -0.0639333870 7.738442e-01 0.1665853652
1947 P51687 SUOX 1.3181201409 1.261956e-08 -0.1012366081
1948 P84103 SRSF3 1.2891684690 6.009634e-05 -0.0919919405
1949 P21399 ACO1 0.1054063310 6.197900e-01 0.2428422205
1950 Q32MZ4 LRRFIP1 0.3632510580 1.125297e-01 -0.1873734274
1951 Q15811 ITSN1 -0.0200925973 9.439519e-01 0.1335478206
1952 P23284 PPIB 0.4016368648 1.902491e-01 0.1240278652
1953 Q9BT09 CNPY3 0.1426578740 4.456442e-01 -0.1369132601
1954 P36871 PGM1 0.7071756094 1.389818e-03 0.1980879304
1955 P11117 ACP2 0.0440008418 8.746155e-01 -0.0920412487
1956 Q99700 ATXN2 -0.0249898086 9.112628e-01 0.2525084456
1957 P62333 PSMC6 0.0414103976 8.718443e-01 0.1092616396
1958 O00159 MYO1C 0.5776184258 9.362778e-04 0.1195647718
1959 P11279 LAMP1 -0.6347087295 7.318359e-02 0.1754433704
1960 P82664 MRPS10 0.0300941178 8.638571e-01 -0.1603465862
1961 P21926 CD9 -1.1353037654 6.391773e-03 0.4607441303
1962 Q9NR19 ACSS2 0.4434773080 3.407810e-02 0.3602161255
1963 Q9HAV7 GRPEL1 -0.2872256298 1.767325e-01 -0.2937040729
1964 P60981 DSTN 0.0613880656 8.155761e-01 0.1293255070
1965 Q9UKX2 MYH2 1.5995453403 2.936946e-03 0.1228670487
1966 Q7L775 EPM2AIP1 -0.4468333524 4.801878e-02 -0.2945009993
1967 Q5TC12 ATPAF1 0.3745649103 9.720010e-02 0.1273674588
1968 Q14696 MESD 0.5874278948 3.633019e-03 0.1601022524
1969 P24390 KDELR1 0.3645262940 3.847837e-02 -0.6319949280
1970 P15259 PGAM2 1.3221396063 7.599926e-03 0.1491572499
1971 P46937 YAP1 -0.6938726648 3.686012e-05 -0.1672168492
1972 Q15738 NSDHL 0.2802517274 3.302512e-02 0.1139328640
1973 P29692 EEF1D -0.5515698350 4.801212e-06 -0.1942462621
1974 Q13492 PICALM 0.1757807814 3.326360e-01 -0.1330187061
1975 Q9BV79 MECR -0.2169496192 1.244770e-01 0.2060868424
1976 P04626 ERBB2 1.5185983895 1.391522e-06 -0.1160366021
1977 Q7KZF4 SND1 0.5709247746 4.507875e-04 -0.0944147087
1978 P13591 NCAM1 1.0425527917 1.475188e-04 0.1359207349
1979 Q9H4G4 GLIPR2 -0.8726009629 1.435338e-01 -0.1377189249
1980 Q9BW91 NUDT9 0.5778246744 2.560287e-03 0.0939589999
1981 P35914 HMGCL -0.7507578460 1.150621e-05 0.1043407372
1982 P36551 CPOX -0.5409078890 4.832631e-03 -0.1052286710
1983 Q13330 MTA1 0.4177181242 6.967793e-03 -0.1539773030
1984 Q5T0D9 TPRG1L 0.0619930937 7.863513e-01 0.1337896782
1985 Q9H6K4 OPA3 1.0512981873 5.119571e-07 -0.2536091609
1986 P45954 ACADSB 0.0465525644 8.530599e-01 0.1093543052
1987 Q96MU7 YTHDC1 0.0953811645 6.055396e-01 0.1431320158
1988 P49915 GMPS 0.3891110973 4.962040e-03 0.1687013129
1989 Q9UI47 CTNNA3 1.6839019804 9.180409e-04 0.1572445637
1990 Q93009 USP7 -0.1181368389 3.942116e-01 0.0848902434
1991 P11182 DBT 0.1493468639 2.903078e-01 0.1053534927
1992 P61619 SEC61A1 -0.3498077658 2.947810e-01 -0.1798585110
1993 Q96HP0 DOCK6 0.1986534823 6.773818e-01 -0.1852202414
1994 Q9NP90 RAB9B 2.3479670371 5.184398e-08 -0.2282349511
1995 Q9UL54 TAOK2 0.8273022724 1.585060e-09 -0.1331274024
1996 P82909 MRPS36 0.6037590805 3.134948e-02 -0.1503714294
1997 Q9BYV6 TRIM55 -0.0249223865 9.277871e-01 -0.0941274403
1998 O75396 SEC22B 0.2198585093 1.556393e-01 -0.1582100924
1999 Q53GS9 USP39 0.1950545675 1.074006e-02 -0.1223646655
2000 Q9UM00 TMCO1 -0.1557144385 2.512859e-01 -0.2788674167
2001 P10644 PRKAR1A -0.0500805377 8.882699e-01 -0.2009798037
2002 Q9UGV2 NDRG3 1.0968856862 2.489318e-06 -0.1642863515
2003 Q5JRA6 MIA3 0.4869522066 5.922553e-03 0.2517651870
2004 P82675 MRPS5 0.1733821004 2.569455e-01 -0.1189895730
2005 Q9UQB3 CTNND2 0.5472299676 4.133040e-02 -0.1132828115
2006 Q8NBU5 ATAD1 0.2996948430 1.737459e-01 0.1344889029
2007 P08582 MELTF -0.8051590739 6.821040e-02 0.2632308677
2008 P36543 ATP6V1E1 -1.0903026949 1.234720e-11 -0.2839601305
2009 Q06323 PSME1 0.0677612368 7.809287e-01 -0.1809043530
2010 Q9P0L0 VAPA -0.3390880755 5.894954e-02 -0.1079442040
2011 Q6P1X6 C8orf82 0.6919838723 7.940349e-03 -0.0919210459
2012 P10606 COX5B 0.1136845784 7.808695e-01 -0.1385477506
2013 O75976 CPD -0.3720645013 1.305032e-01 0.1402636759
2014 Q15393 SF3B3 0.6033894698 3.130775e-04 -0.1082147945
2015 P78371 CCT2 0.1387950818 6.615389e-01 0.1060104999
2016 Q9BSJ5 C17orf80 -1.9094758017 1.826841e-06 -0.3300467973
2017 O95298 NDUFC2 0.2171100335 2.916878e-01 -0.2176380759
2018 Q6UY14 ADAMTSL4 0.2640725434 3.106133e-01 0.5124778155
2019 Q13557 CAMK2D 0.7896298789 8.483366e-05 0.1396464367
2020 Q9Y4F3 MARF1 -0.6213787707 1.966890e-05 0.1849873854
2021 Q02809 PLOD1 0.5021732260 4.207209e-02 -0.1161368344
2022 Q8TB37 NUBPL 0.2889109415 1.650630e-01 0.1841135011
2023 P12694 BCKDHA 0.0418078579 9.417757e-01 0.1132479572
2024 Q9BUR5 APOO 0.8972709740 4.653243e-03 -0.1097208441
2025 Q9H9J2 MRPL44 -0.6020990218 5.948296e-09 -0.2216553149
2026 Q96S66 CLCC1 0.4053448262 1.791996e-02 0.1348035251
2027 Q9NWB6 ARGLU1 -0.3034139972 6.762886e-02 0.2356284579
2028 Q8WWV3 RTN4IP1 1.1387567419 1.291165e-07 0.1552915531
2029 P48147 PREP 0.5312112286 2.689724e-03 0.2229599558
2030 Q16576 RBBP7 0.4930926376 2.598395e-02 -0.1129805033
2031 O95831 AIFM1 0.3042610253 1.506253e-01 0.1175729384
2032 Q9BTC0 DIDO1 0.0081538646 9.673552e-01 -0.5603799007
2033 P33527 ABCC1 -0.5059668958 3.604825e-02 0.1192798867
2034 Q7L9L4 MOB1B -1.0788648618 3.975851e-07 0.2850250352
2035 P48556 PSMD8 -0.6539189031 2.549062e-07 -0.1177878913
2036 Q96RQ3 MCCC1 0.5068670420 2.622499e-04 -0.1306215778
2037 Q9NWM8 FKBP14 0.9259873757 1.926029e-03 -0.3068203340
2038 O95159 ZFPL1 -0.3443103880 6.845974e-03 -0.1089420401
2039 Q9NQE9 HINT3 0.0146610053 9.466218e-01 -0.2140358593
2040 Q00765 REEP5 -0.0498913897 8.026646e-01 0.1066922979
2041 P13667 PDIA4 0.1867214309 6.356035e-01 0.1173837438
2042 P23258 TUBG1 0.3404453465 5.861478e-03 0.1281586003
2043 Q96AN5 TMEM143 0.9747646338 3.461372e-03 -0.1559450159
2044 O60256 PRPSAP2 -1.0903066790 1.788167e-10 -0.1024336555
2045 Q9NTJ5 SACM1L -0.2267662753 3.417828e-01 -0.1611255677
2046 Q5JTZ9 AARS2 1.0525817491 1.371412e-05 0.1072285522
2047 P62820 RAB1A -0.7960844766 1.573876e-07 -0.0970143479
2048 P49748 ACADVL -0.5215803449 4.066065e-04 0.0980933538
2049 Q2TAA5 ALG11 0.0794104546 7.969870e-01 -0.1054766979
2050 P49753 ACOT2 -0.1800431002 7.401664e-01 0.1185292661
2051 Q92499 DDX1 0.8726358372 3.619793e-07 -0.0837789331
2052 O75643 SNRNP200 0.0243711566 8.839931e-01 0.0791359883
2053 Q9P0S9 TMEM14C -0.3607514130 2.138033e-01 -0.1178194013
2054 Q14192 FHL2 1.5223476866 1.765607e-02 -0.1693795768
2055 O60664 PLIN3 -0.3496687575 1.273580e-01 0.1613657814
2056 P82673 MRPS35 0.6611793127 4.555276e-06 -0.0989629001
2057 Q9Y512 SAMM50 0.1916689996 1.419957e-01 0.0902401783
2058 O43747 AP1G1 0.0283419493 9.060774e-01 0.2260558350
2059 Q9BYD6 MRPL1 0.4579710660 8.064139e-02 -0.1457402759
2060 Q9NZ01 TECR 0.4524086470 3.547010e-03 0.0966267844
2061 P00492 HPRT1 0.1575700639 7.224271e-01 0.3826193809
2062 O60669 SLC16A7 1.6263558051 9.193574e-07 -0.2439902363
2063 Q9P0T7 TMEM9 0.2286258113 2.548708e-01 -0.2897704100
2064 O60331 PIP5K1C -0.3896952797 4.796960e-02 0.1213932177
2065 Q99442 SEC62 0.0476309248 8.008723e-01 -0.1253172696
2066 Q9NZ32 ACTR10 0.0855859427 6.892018e-01 -0.2943213697
2067 Q8N0X4 CLYBL 0.3804443378 4.146781e-01 0.3756555127
2068 Q9H6Z4 RANBP3 -0.0074115872 9.631476e-01 0.2582655819
2069 Q9NTG7 SIRT3 -0.2571646352 3.838222e-01 0.2295703517
2070 P26599 PTBP1 -0.2950528569 4.211937e-01 -0.1032980210
2071 Q9UKP3 ITGB1BP2 2.0604218697 2.109661e-05 -0.2791393242
2072 P17980 PSMC3 0.2273719907 2.332383e-02 0.0926776020
2073 Q9NVS2 MRPS18A -0.0402082025 8.031348e-01 -0.1106006243
2074 Q02338 BDH1 2.1157291743 5.303489e-04 0.0995037586
2075 Q9H6R4 NOL6 -0.4310167487 1.700926e-01 -0.2318329234
2076 Q53GG5 PDLIM3 -0.8674231586 2.768987e-01 0.1751096875
2077 P30049 ATP5F1D 0.8888212343 3.257062e-03 -0.1321410744
2078 Q9NRW1 RAB6B 0.6111505322 7.677371e-03 -0.1501626685
2079 P11387 TOP1 -0.3960226533 1.712180e-02 -0.0999382249
2080 P26358 DNMT1 1.0374283384 4.595571e-10 0.1961702509
2081 Q96AQ8 MCUR1 0.0386033469 8.367774e-01 -0.2665467709
2082 P53990 IST1 -0.3967481091 2.203305e-03 -0.4385883218
2083 Q15084 PDIA6 -0.0316269750 9.313407e-01 0.1304443104
2084 P61006 RAB8A 0.5204945315 6.672035e-03 -0.1065776955
2085 P16671 CD36 1.3086566808 6.254709e-02 -0.1614489475
2086 O75874 IDH1 0.7789141704 2.457396e-03 -0.2719364230
2087 Q9NR77 PXMP2 0.7838406018 8.064319e-03 -0.3388657821
2088 P30153 PPP2R1A -0.0026459700 9.890591e-01 0.0981272779
2089 Q8N697 SLC15A4 0.2649307754 3.593882e-01 0.2328756144
2090 Q9Y371 SH3GLB1 -0.5369464880 4.355728e-02 -0.2799289032
2091 Q16270 IGFBP7 -0.0553297749 8.820208e-01 -0.1735731130
2092 P06753 TPM3 0.1100660054 8.361777e-01 -0.4929113011
2093 P13674 P4HA1 0.4657140377 2.025001e-01 -0.0922032534
2094 P48637 GSS -0.1895269333 1.869396e-01 -0.2779636141
2095 O43824 GTPBP6 0.4602950667 1.395504e-03 -0.2734504237
2096 P17661 DES 1.6751198127 5.708764e-02 0.4497415915
2097 Q7LGA3 HS2ST1 -0.3940804973 9.973634e-02 -0.1073078980
2098 Q9UI14 RABAC1 -0.2886104805 1.764840e-01 -0.1876504937
2099 P48730 CSNK1D -0.4763333110 7.179966e-04 0.2062944598
2100 Q86VM9 ZC3H18 0.0016572135 9.932779e-01 -0.1898250821
2101 Q7KZ85 SUPT6H -0.2880921875 1.533015e-01 -0.1685498276
2102 O60313 OPA1 0.2543018841 9.554793e-02 0.1044799417
2103 P49368 CCT3 0.4268448363 4.046655e-05 0.0999937434
2104 Q9NSD9 FARSB 0.9403096582 5.430703e-08 0.0935948268
2105 Q15102 PAFAH1B3 1.2245017608 9.140099e-08 -0.3013653463
2106 P53004 BLVRA 0.4111088016 1.230085e-02 0.2822536255
2107 Q96KN1 LRATD2 -0.2446503381 4.592222e-01 -0.3061198829
2108 Q8NE79 BVES 1.4326553411 7.542194e-06 0.0752190673
2109 P29536 LMOD1 3.1782789254 8.557605e-10 0.1644296131
2110 P50897 PPT1 0.9741334443 5.476262e-03 -0.1573011749
2111 Q16186 ADRM1 -0.7835078963 3.213693e-09 0.2551237886
2112 P50579 METAP2 -0.0599410000 7.424054e-01 0.3789248124
2113 Q02218 OGDH 0.1151495497 4.763414e-01 0.0946360809
2114 Q92796 DLG3 0.0836581500 7.209849e-01 0.1547593964
2115 P09874 PARP1 1.2169672572 2.774678e-08 0.1457073318
2116 Q96ND0 FAM210A 0.7832647817 1.615588e-03 -0.1786974852
2117 P42704 LRPPRC -0.5276565080 4.153601e-03 -0.1012872358
2118 Q93050 ATP6V0A1 -0.9783735854 1.119784e-03 0.1174575184
2119 P11310 ACADM 0.3200875712 3.319724e-01 0.1087991394
2120 P17612 PRKACA -0.4313467858 8.929479e-02 0.1294518467
2121 Q96JM3 CHAMP1 -0.2339891329 1.856538e-01 -0.1804230458
2122 Q96A26 FAM162A 0.4943920832 4.654980e-01 -0.1753460633
2123 O60229 KALRN 0.0660899933 8.703066e-01 0.6861820167
2124 P51795 CLCN5 -1.1586569450 4.289188e-02 0.1918283846
2125 P58876 H2BC5 -1.2798282928 2.306805e-05 0.1414397274
2126 P45880 VDAC2 0.1819745631 3.549004e-01 0.0846556240
2127 Q92831 KAT2B -1.4585588026 1.205558e-07 -0.2659856053
2128 Q86U86 PBRM1 0.1982857723 1.405046e-01 -0.2355238688
2129 Q13616 CUL1 -0.0929825149 5.173780e-01 -0.1159312603
2130 P12814 ACTN1 -0.4309626504 3.900074e-01 0.2095158169
2131 Q92968 PEX13 0.4610680112 2.732571e-03 -0.4157903448
2132 P38159 RBMX 0.8503418139 6.771555e-05 -0.1113749380
2133 Q9BX68 HINT2 0.3337722805 1.996118e-01 0.1161351290
2134 Q8TEQ6 GEMIN5 0.3169870947 5.899150e-02 -0.2726417501
2135 Q96CN7 ISOC1 0.6062568892 5.940723e-02 0.1210246679
2136 P15311 EZR 0.7365071191 1.448667e-05 0.0848442530
2137 Q9HBH5 RDH14 0.0640385155 8.270659e-01 0.1034871730
2138 P13533 MYH6 2.6154693930 7.116697e-09 0.2476201453
2139 Q9Y285 FARSA 0.2534751718 2.042847e-01 -0.1575405030
2140 P51452 DUSP3 0.1740663875 5.069760e-01 -0.2838945881
2141 Q6DKK2 TTC19 -0.1962182345 1.964601e-01 -0.2687302665
2142 P30837 ALDH1B1 -0.8517062256 2.544079e-02 0.1980954870
2143 P14672 SLC2A4 1.6302501747 9.199969e-04 -0.1693895431
2144 Q9Y6B6 SAR1B 0.5346682497 1.691695e-04 -0.1423709405
2145 Q9UHQ9 CYB5R1 0.5458996455 1.670314e-02 0.1023200639
2146 Q13796 SHROOM2 -0.5983633213 9.919486e-02 -0.2184100347
2147 O60662 KLHL41 0.6103980614 1.342304e-01 0.1576033040
2148 Q08357 SLC20A2 1.3158173086 4.610660e-07 0.1632916359
2149 Q8NBM8 PCYOX1L -1.1223898034 6.889023e-07 0.1021725140
2150 Q8IV08 PLD3 0.2320951973 2.799846e-01 0.1057716482
2151 Q12906 ILF3 0.1970056909 2.071025e-01 -0.0739419192
2152 P13073 COX4I1 0.2390963512 4.112933e-01 -0.0941046311
2153 Q709C8 VPS13C -0.7426917078 9.377918e-05 0.5567733277
2154 P51649 ALDH5A1 0.1085656600 6.413752e-01 0.1188716514
2155 Q07021 C1QBP 1.0392634810 4.251062e-08 0.1341548659
2156 O15269 SPTLC1 -0.6254079075 7.575681e-04 -0.1014993198
2157 Q9Y6C9 MTCH2 0.6885775260 2.562630e-05 0.0920632675
2158 Q15031 LARS2 0.1095651629 6.535154e-01 0.0830265367
2159 P18084 ITGB5 0.2789205655 4.714806e-01 0.1178529959
2160 P11277 SPTB 0.3071476653 3.158852e-01 0.1087674664
2161 P33991 MCM4 0.5335065626 1.011400e-01 0.2768044646
2162 Q9H6U6 BCAS3 0.5287596931 3.371953e-02 -0.1314082211
2163 Q6UB35 MTHFD1L -0.3169301398 1.984854e-01 -0.1219872828
2164 Q5HYK3 COQ5 0.2405829159 2.354522e-01 0.1056491090
2165 Q9NRP0 OSTC 0.5667623757 1.131441e-02 -0.1283539466
2166 P21281 ATP6V1B2 -0.4857983051 2.239842e-02 -0.1003376983
2167 Q9NZE8 MRPL35 0.9341455701 3.583120e-05 -0.1057187487
2168 O15344 MID1 0.5082765108 1.113637e-01 -0.2140228002
2169 Q9H8Y8 GORASP2 0.5253634640 4.746911e-04 0.1189427241
2170 Q9HCM2 PLXNA4 1.6632168204 6.838493e-04 -0.2088961218
2171 O75746 SLC25A12 2.2971653888 2.992524e-07 0.0962979309
2172 Q9Y3E1 HDGFL3 -0.4240065194 1.567336e-03 0.1094022386
2173 P27695 APEX1 0.8043768497 6.101284e-09 0.1462977043
2174 Q6NXT6 TAPT1 -0.9337846330 2.414441e-09 0.5165688842
2175 P27797 CALR 0.4182562575 1.423336e-01 0.1188448055
2176 O43776 NARS1 0.5274102662 7.701333e-04 0.1329451073
2177 Q9NXA8 SIRT5 -0.1908772118 2.928658e-01 0.0963912099
2178 P26583 HMGB2 0.7445039339 1.273074e-01 0.1398682501
2179 P26639 TARS1 0.2337347050 1.546895e-01 0.0859174106
2180 Q8IX12 CCAR1 -0.1417217972 3.791233e-01 0.0973916468
2181 P13797 PLS3 -0.6275368199 1.528067e-01 0.3294577858
2182 P49959 MRE11 0.1021459640 7.272842e-01 -0.1035949163
2183 O75947 ATP5PD 0.4118021525 1.353475e-01 -0.1058417568
2184 Q96GC9 VMP1 -0.2233382697 4.236564e-01 0.1094297534
2185 Q3SXM5 HSDL1 -0.1854799199 1.637189e-01 0.1196860011
2186 Q9BUL8 PDCD10 0.1918238493 4.235083e-01 -0.1721965292
2187 Q9UNS2 COPS3 -0.3244069419 4.765550e-03 0.2358430178
2188 P09417 QDPR 1.3486861831 8.097095e-09 -0.3650271906
2189 Q8TBQ9 TMEM167A -0.2189356800 7.927123e-02 0.0918088877
2190 Q01081 U2AF1 -0.0676163742 6.882073e-01 -0.0812919777
2191 Q9BRJ2 MRPL45 -0.0074385286 9.564850e-01 0.0907640999
2192 Q587I9 SFT2D3 -0.1349562351 5.906045e-01 -0.2000855117
2193 Q06787 FMR1 -0.6787913571 3.034775e-06 -0.2336430828
2194 P14866 HNRNPL -0.3486817978 6.150589e-03 -0.0752068166
2195 Q16537 PPP2R5E -0.2411305096 4.593771e-02 0.1207502672
2196 Q86W92 PPFIBP1 -0.2695018573 3.849201e-01 0.2147703958
2197 Q08170 SRSF4 0.1046135096 5.170669e-01 -0.2833920949
2198 P61011 SRP54 0.0336708567 8.227996e-01 0.0980445736
2199 Q6PD62 CTR9 -0.4087626385 1.213051e-03 -0.1536421186
2200 Q9H2M9 RAB3GAP2 -0.2033143942 1.300085e-01 -0.4297291464
2201 P04843 RPN1 0.0096436904 9.739276e-01 0.0737346295
2202 P35609 ACTN2 1.2117782012 2.205256e-03 0.1734007188
2203 O14639 ABLIM1 0.0752236362 7.385530e-01 0.1117955619
2204 P78357 CNTNAP1 0.8555630102 1.917259e-03 0.1205849581
2205 P51159 RAB27A 0.3175894687 3.343181e-01 -0.3207193545
2206 Q96SL4 GPX7 0.4885060433 4.088528e-01 -0.1548600142
2207 P35573 AGL 1.9252456142 3.197106e-05 0.1639074520
2208 O00116 AGPS 0.1102369880 3.853408e-01 0.1203514909
2209 Q8TAT6 NPLOC4 -0.5649133255 5.242117e-04 -0.1280768636
2210 Q9H0R6 QRSL1 0.5923842305 5.290926e-04 -0.1416605055
2211 Q12893 TMEM115 -0.3399088918 3.191682e-02 -0.1113613082
2212 Q9NP80 PNPLA8 -0.3398051775 1.331941e-01 -0.1098357922
2213 Q8NE62 CHDH 0.5216138962 2.483114e-01 -0.3189583107
2214 Q14151 SAFB2 -0.3802483246 2.512862e-02 0.1608753759
2215 A0FGR8 ESYT2 -1.3269197946 1.313129e-09 0.1680761578
2216 Q16836 HADH 0.5652787068 7.400782e-02 0.0870007334
2217 O43242 PSMD3 0.5980642266 6.966096e-07 0.0715412654
2218 Q86UL3 GPAT4 0.5470342177 5.963664e-03 -0.1374402276
2219 Q9BUJ2 HNRNPUL1 0.3559651845 1.639440e-02 -0.0845387504
2220 A5D6W6 FITM1 2.9683729634 1.358940e-02 -0.1310341467
2221 Q14764 MVP -0.2186500682 5.048069e-01 0.2875435215
2222 Q5BKX8 CAVIN4 0.4095006651 4.927518e-01 -0.3582403310
2223 Q02487 DSC2 1.0338189168 7.396651e-07 -0.2992525080
2224 Q9BQB6 VKORC1 0.3845824815 8.360751e-02 -0.1013794478
2225 P52179 MYOM1 1.9131442462 4.139588e-06 0.1245090072
2226 P62070 RRAS2 -0.1147385118 7.171943e-01 0.1169775237
2227 P49841 GSK3B -0.2447104250 9.266246e-02 0.1039484149
2228 Q8WXH0 SYNE2 0.4007482729 2.634036e-01 -0.3775847726
2229 O75845 SC5D 0.0618347845 9.166914e-01 -0.1260903235
2230 Q8IWX7 UNC45B 1.6474271890 2.027930e-06 -0.1210657317
2231 O14786 NRP1 1.0497861474 5.695981e-04 0.0870340184
2232 Q9H7Z7 PTGES2 0.9439969548 6.628375e-05 -0.0882905799
2233 P26006 ITGA3 -1.0814857623 2.601634e-02 -0.0830500422
2234 Q07817 BCL2L1 -1.2532111388 6.403973e-06 0.2486727601
2235 Q9UBR2 CTSZ -0.2193216438 4.541611e-01 0.1624464050
2236 Q86UE4 MTDH 0.1942338189 1.364889e-01 0.0729566441
2237 Q9UEW8 STK39 1.4645881202 3.238939e-08 0.1523180829
2238 P04004 VTN 0.3077547388 5.288148e-01 -0.2017070163
2239 O00214 LGALS8 -0.2246548423 4.490987e-01 0.1134130640
2240 Q12959 DLG1 0.5909028405 7.386090e-05 0.1109538226
2241 O60568 PLOD3 -0.2874368588 3.387479e-01 0.1068054840
2242 Q09161 NCBP1 0.2782718810 6.818212e-03 -0.0960413079
2243 P21283 ATP6V1C1 -0.1823192948 2.872729e-01 0.0873761706
2244 Q13636 RAB31 -1.1282784068 2.697689e-06 -0.5314522470
2245 P51790 CLCN3 0.8674120740 1.262030e-06 -0.1006003504
2246 O43772 SLC25A20 -0.2696840049 4.471466e-02 0.0940390925
2247 Q8N0U8 VKORC1L1 0.0850412058 7.524273e-01 0.1086948704
2248 P25786 PSMA1 0.6970245582 4.427227e-05 -0.0847909552
2249 Q13561 DCTN2 0.0309189326 8.268671e-01 -0.1095230216
2250 P46459 NSF -0.6141520033 2.017168e-03 0.0804018831
2251 Q8WWI1 LMO7 0.2695588353 2.100990e-01 -0.0892285079
2252 P05455 SSB 0.2220353768 9.929410e-02 0.0858122234
2253 Q7Z406 MYH14 0.7144758894 7.784809e-01 0.1126757023
2254 P21741 MDK -0.6601513678 7.623460e-02 0.2790916802
2255 Q99816 TSG101 -0.5358082905 5.565489e-08 -0.1254203323
2256 Q12802 AKAP13 0.2634402096 3.787848e-01 -0.2257237044
2257 P15151 PVR -0.2249349449 6.252877e-01 0.1422126943
2258 Q6IAA8 LAMTOR1 -0.0818105779 6.018847e-01 -0.1009985723
2259 Q96FV9 THOC1 0.8930647640 8.605784e-05 -0.1370294243
2260 Q9NP92 MRPS30 0.0935161655 6.658838e-01 -0.0847089711
2261 Q9ULD5 ZNF777 -0.1619445131 4.949122e-01 -0.1562769431
2262 Q7L8L6 FASTKD5 -0.4734031845 3.057090e-03 -0.1159447822
2263 O43676 NDUFB3 0.0348197043 9.200086e-01 0.0766864847
2264 O43920 NDUFS5 0.2235269835 5.393581e-01 -0.0739795048
2265 O15126 SCAMP1 0.2246440150 2.588138e-01 -0.0859143980
2266 P50613 CDK7 -0.0264044520 9.191317e-01 -0.1254557060
2267 Q9H490 PIGU 1.4090850298 5.930049e-07 0.0972435828
2268 Q15154 PCM1 -0.4528419457 9.935505e-03 0.1487439410
2269 Q8NFJ5 GPRC5A -1.6984613127 1.080710e-01 -0.2717517921
2270 Q02880 TOP2B 0.7928685525 2.583391e-11 0.0926080440
2271 Q7Z4H8 POGLUT3 1.5871024102 9.307457e-06 -0.1261352630
2272 P07900 HSP90AA1 0.2268566605 2.598713e-01 0.0905068804
2273 Q92890 UFD1 -0.3420062623 2.671656e-02 0.0887659687
2274 P82663 MRPS25 0.2122163225 2.916822e-01 0.0737885897
2275 Q16611 BAK1 -1.0772691463 9.510081e-04 -0.1149831719
2276 Q8N6H7 ARFGAP2 -0.1746849878 2.593567e-01 -0.3374250700
2277 Q9NVE7 PANK4 0.4321126233 1.797828e-02 0.1101018370
2278 Q15772 SPEG 1.4638370318 1.034254e-05 -0.1303646584
2279 P36507 MAP2K2 -0.1340735619 2.711267e-01 -0.2287493177
2280 O75821 EIF3G 0.0733741808 5.892635e-01 -0.1123255760
2281 Q9UPT8 ZC3H4 0.1977910173 2.150821e-01 -0.2464342913
2282 Q9NWH9 SLTM -0.0757628687 6.765655e-01 0.0908403974
2283 P01111 NRAS 0.3781786546 1.650738e-01 0.0738348777
2284 Q9P212 PLCE1 1.4128238530 1.758350e-05 0.1415246291
2285 P61077 UBE2D3 -0.2002922092 5.102552e-02 0.1467192230
2286 P14625 HSP90B1 0.4111294033 2.839828e-01 0.1024254477
2287 Q9BUT1 BDH2 0.6852905713 2.828355e-03 -0.1776385918
2288 Q9Y266 NUDC 0.3984925061 1.546301e-03 0.1157182200
2289 Q7Z4L5 TTC21B 0.7398097408 4.465813e-04 0.1374880575
2290 Q04446 GBE1 0.6553690204 5.264471e-03 0.1531357716
2291 O95232 LUC7L3 0.4983608791 9.545049e-03 -0.2887169637
2292 P62308 SNRPG 0.0172793718 9.547250e-01 -0.1457515613
2293 Q8IWW8 ADHFE1 0.1476809359 7.646353e-01 0.0985074284
2294 P15822 HIVEP1 -0.4079514547 1.613442e-01 -0.2172658475
2295 O94766 B3GAT3 -0.3922927046 1.426625e-01 -0.1352594561
2296 P34059 GALNS 0.3643727308 2.489842e-01 0.0921715696
2297 P30626 SRI 1.0432623040 3.476572e-06 -0.1421325502
2298 P34897 SHMT2 0.6745794025 8.732723e-05 -0.1104163534
2299 P09001 MRPL3 0.9374300831 1.496252e-07 -0.1001257790
2300 Q8WUK0 PTPMT1 0.7486204849 4.880568e-04 -0.1163135089
2301 Q8IZP0 ABI1 -0.0162363756 9.215519e-01 -0.1736190624
2302 Q9Y6M4 CSNK1G3 -0.0350858181 8.529185e-01 -0.2649024029
2303 P52758 RIDA 0.3317649635 2.271529e-01 0.1021859031
2304 P53801 PTTG1IP 0.1249992232 5.294926e-01 0.0838829868
2305 O75533 SF3B1 -0.0336202692 8.344448e-01 0.0894425931
2306 P82912 MRPS11 0.0559313376 7.857749e-01 0.0851335858
2307 Q9NZJ0 DTL 2.3985535906 7.819813e-07 -0.0843045692
2308 P29972 AQP1 2.2547102483 6.643097e-09 0.1341601670
2309 Q9NZI8 IGF2BP1 0.7446256123 2.260722e-05 -0.0839610247
2310 P14406 COX7A2 0.0777922045 8.548331e-01 -0.1699268375
2311 O14556 GAPDHS 0.7770135718 4.500282e-02 0.2212492989
2312 O14497 ARID1A -0.0030497592 9.901463e-01 -0.1342770987
2313 Q9H0E2 TOLLIP -0.5405509152 6.234638e-05 0.0897206701
2314 O95870 ABHD16A 0.5159231881 3.662427e-03 0.0747185461
2315 P39656 DDOST -0.4314026965 8.033659e-02 0.0828491160
2316 Q9UHA4 LAMTOR3 -0.3719507199 7.607481e-03 -0.0896908867
2317 Q9BT17 MTG1 -0.0142030324 9.478949e-01 0.0815812425
2318 Q15029 EFTUD2 -0.2037573353 1.365262e-01 -0.0618426621
2319 Q9C0J8 WDR33 0.2433898445 7.727531e-02 -0.3324290100
2320 P61221 ABCE1 0.5948428427 5.176238e-06 0.1800819437
2321 P21980 TGM2 0.6571123409 5.760362e-02 0.1409626170
2322 O14672 ADAM10 -0.3686718880 2.818300e-01 -0.1065539456
2323 P49023 PXN -0.2555707420 1.725348e-01 -0.1027252454
2324 Q9Y6N7 ROBO1 0.6055548432 6.889263e-02 0.1904771436
2325 P60953 CDC42 -0.2062601515 1.404962e-01 -0.0619750593
2326 P20700 LMNB1 -0.0401274632 8.797037e-01 0.0736560770
2327 P09525 ANXA4 -2.0762293471 1.775044e-10 0.1921985332
2328 Q5VST9 OBSCN 1.9657388755 9.141551e-06 0.1144003231
2329 P36776 LONP1 0.1993639520 1.989495e-01 0.0730809005
2330 Q8IZ81 ELMOD2 0.5734409147 1.816252e-02 0.0831898312
2331 Q8TCJ2 STT3B 0.2127207135 2.548533e-01 0.0889680834
2332 O96005 CLPTM1 -0.1382258477 5.283851e-01 0.1025729723
2333 Q9UNH7 SNX6 0.6293863778 3.499151e-05 0.1144396456
2334 O60884 DNAJA2 0.0634284390 6.324113e-01 0.0786412110
2335 Q9BTY2 FUCA2 0.4167218015 2.410173e-01 0.0884052326
2336 P51148 RAB5C -0.4251364040 1.835069e-01 -0.1127880732
2337 Q9Y679 AUP1 -0.3700852374 1.829319e-02 0.1281353183
2338 Q9Y399 MRPS2 0.8713937049 6.025728e-08 -0.1081825184
2339 Q9NP58 ABCB6 -1.7819160928 1.071398e-08 -0.2081219846
2340 P25686 DNAJB2 -0.3764083310 5.021972e-02 -0.4409429218
2341 Q8NFD5 ARID1B 0.1649458813 3.779063e-01 0.1173360257
2342 Q9HC21 SLC25A19 -0.5451086200 2.190423e-02 0.1441435639
2343 Q9Y3A5 SBDS 0.4518700340 1.258558e-02 -0.2567924331
2344 Q7Z7H5 TMED4 -0.1400053220 2.312305e-01 0.0845505602
2345 Q9NX62 BPNT2 0.0824927707 6.090531e-01 -0.1586894490
2346 Q9NV96 TMEM30A -0.3802463385 8.611958e-02 -0.1079970578
2347 Q6JBY9 RCSD1 1.4050248084 2.002982e-03 -0.2245187743
2348 Q7Z3C6 ATG9A 0.4232071809 2.680046e-03 0.1369346901
2349 O15118 NPC1 -0.6786219897 2.564494e-02 0.1870225847
2350 O94875 SORBS2 0.8466433842 7.652204e-04 0.1058970244
2351 P43243 MATR3 0.1346123482 5.733979e-01 -0.0599042013
2352 O00410 IPO5 0.0388070439 8.220781e-01 0.0771344886
2353 Q5T3F8 TMEM63B -0.8899017684 2.523434e-05 0.4780829378
2354 P52789 HK2 0.1052990652 8.475792e-01 -0.1481672261
2355 P21266 GSTM3 0.1396641502 6.626186e-01 0.1084883898
2356 Q00610 CLTC 0.4570964549 8.554795e-04 -0.1013205733
2357 Q9NXG0 CNTLN 0.8301658116 2.358548e-03 -0.0710025079
2358 Q8WVM8 SCFD1 -0.0166513041 9.101552e-01 -0.0876495577
2359 P16152 CBR1 0.3369572776 3.665830e-01 0.1268421232
2360 Q9NVC3 SLC38A7 -0.0230360023 9.398638e-01 -0.1204226051
2361 P50148 GNAQ -0.5176245426 2.150925e-02 0.3021785170
2362 P18031 PTPN1 -1.0298878141 2.400114e-05 0.1311139807
2363 P30825 SLC7A1 0.9445964951 3.420367e-04 -0.1813939844
2364 Q9HCP6 HHATL 1.2634805253 2.191637e-01 0.2888851845
2365 O75381 PEX14 0.3491617120 2.690376e-02 -0.3211125770
2366 Q15427 SF3B4 0.1870032303 1.920420e-01 0.0870051810
2367 Q8NBJ7 SUMF2 0.5456688017 5.050998e-02 -0.2050417704
2368 Q96KM6 ZNF512B 1.2616455509 1.903062e-04 0.1082226486
2369 P13637 ATP1A3 2.8038238320 3.926380e-08 -0.0967763612
2370 Q9HD45 TM9SF3 0.1313191994 4.994314e-01 -0.0819738690
2371 Q96EY8 MMAB 0.6748654000 9.696859e-05 0.1012971614
2372 Q9H1I8 ASCC2 -0.0170807523 9.416420e-01 -0.1393803706
2373 Q9Y6K1 DNMT3A 0.0163411504 9.416420e-01 -0.0977244009
2374 Q9H300 PARL -0.1307387069 2.023490e-01 -0.1082308510
2375 Q7Z3K3 POGZ 0.4362730969 5.150607e-03 -0.1207296815
2376 Q99439 CNN2 0.8377840511 5.309659e-02 0.2513663604
2377 P51648 ALDH3A2 0.5719194395 1.389925e-02 0.0906536098
2378 Q12830 BPTF -0.1414491576 4.189015e-01 0.0872596919
2379 Q02750 MAP2K1 -0.1052212653 6.661304e-01 -0.1759906539
2380 Q9UHB9 SRP68 -0.9555278494 7.172050e-07 0.1405647965
2381 P11532 DMD 0.8686020943 6.162823e-03 0.0646041166
2382 Q9Y592 CEP83 1.2257758177 3.953353e-06 0.2047931412
2383 P09104 ENO2 0.5985469728 5.799643e-01 0.1608794301
2384 Q5JPH6 EARS2 0.4069693423 1.294753e-01 0.0948825802
2385 Q14699 RFTN1 -0.6521454800 6.470766e-03 0.0949489874
2386 O75694 NUP155 0.5991875782 3.478329e-04 -0.1245720630
2387 Q14008 CKAP5 -0.4389918745 2.524708e-03 0.0912575656
2388 Q7L014 DDX46 0.1218455874 5.104887e-01 -0.0790218635
2389 P52597 HNRNPF -0.3305074757 5.547817e-02 0.0617895394
2390 P08294 SOD3 0.0937949214 7.431747e-01 -0.1946003311
2391 O43264 ZW10 0.7310688837 9.812131e-04 -0.1261748207
2392 O60245 PCDH7 0.7495802771 6.083667e-04 0.1198399987
2393 P11171 EPB41 -0.0254643741 9.279437e-01 0.0931591291
2394 Q04721 NOTCH2 -0.0421000924 9.051863e-01 0.2346299767
2395 Q6UN15 FIP1L1 0.0493975885 7.777428e-01 -0.1282771596
2396 Q9UNF0 PACSIN2 -0.5023746472 5.340197e-04 0.1079347491
2397 Q9BVC4 MLST8 0.4733889899 1.062802e-02 0.3032040546
2398 Q6P1K8 GTF2H2C 0.3244639326 1.200738e-01 -0.1412766968
2399 P51659 HSD17B4 0.5574602088 2.560487e-04 0.0757533862
2400 Q92504 SLC39A7 0.7985954291 1.682925e-05 -0.2901717026
2401 Q5HYJ1 TECRL 1.1552446549 1.236416e-02 -0.0813971200
2402 Q96D71 REPS1 0.3125509237 1.910829e-02 -0.1036203253
2403 Q5CZC0 FSIP2 2.1208301759 8.097095e-09 -0.2871359169
2404 Q709F0 ACAD11 0.0557420518 8.641535e-01 0.0927170442
2405 O43402 EMC8 -0.1140199597 4.358335e-01 -0.1210832613
2406 P30419 NMT1 0.3165557419 2.024316e-03 -0.2153199384
2407 Q9NUI1 DECR2 0.5272927256 4.096170e-02 -0.0881000495
2408 Q9NTZ6 RBM12 -0.5190400624 2.735487e-03 -0.1060989067
2409 Q6Y1H2 HACD2 0.8619514419 3.567381e-02 0.1465031580
2410 Q86YH6 PDSS2 0.6033452360 1.028914e-02 0.1028414606
2411 P08727 KRT19 -1.9500320846 3.126264e-04 -0.1061158880
2412 Q7Z5G4 GOLGA7 0.2375474817 6.133869e-02 -0.1369039624
2413 Q5T9A4 ATAD3B 0.9145547943 9.359890e-06 0.1442396124
2414 Q9BZJ0 CRNKL1 -0.1316039742 3.611632e-01 0.0877489549
2415 Q9BQS7 HEPH 0.2046066661 6.067403e-01 -0.1148999158
2416 Q12874 SF3A3 0.0819311102 6.100667e-01 -0.0595385098
2417 Q9HBM0 VEZT 0.3522668572 3.037280e-02 -0.1374230842
2418 Q9HC38 GLOD4 0.4430369369 1.699268e-04 0.1953545833
2419 P51991 HNRNPA3 -0.1801884270 4.129760e-01 -0.0620973090
2420 P67812 SEC11A 0.0774137063 7.470536e-01 0.0748921936
2421 P61604 HSPE1 0.0924421731 6.975348e-01 -0.0620710869
2422 Q5VWN6 TASOR2 -0.2041902220 1.625263e-01 -0.4288009796
2423 P51911 CNN1 1.2440751036 2.226766e-02 0.1384804369
2424 P78324 SIRPA -0.0376881173 8.597583e-01 -0.0847598614
2425 Q5TB80 CEP162 0.9806911168 2.122293e-05 0.1805441998
2426 Q9NUQ9 CYRIB -0.2160941947 2.692079e-01 0.1091918315
2427 Q8N1F7 NUP93 0.4738018173 2.638992e-04 0.0711521136
2428 Q86Y82 STX12 -1.6124420699 1.844188e-12 -0.0856437451
2429 P23142 FBLN1 0.5082271882 8.116395e-02 0.1297259522
2430 Q9BTZ2 DHRS4 -0.5070912785 1.451382e-02 0.0793866019
2431 Q96JN8 NEURL4 0.7213982353 1.756922e-04 -0.1397817948
2432 Q8NHY6 ZFP28 0.8708184850 1.527098e-03 -0.1475344644
2433 Q9Y282 ERGIC3 0.0160967765 9.399329e-01 -0.0739991423
2434 P08621 SNRNP70 0.0853912404 6.169122e-01 0.0534982205
2435 P06241 FYN -0.0991840519 7.135396e-01 -0.1558970226
2436 O75718 CRTAP 0.2891110521 3.582692e-01 -0.1819304406
2437 O95258 SLC25A14 0.2926980071 1.679156e-01 0.1631335603
2438 P51511 MMP15 1.2192276705 7.380313e-06 -0.1290989825
2439 P54098 POLG -0.5059588808 4.352882e-03 0.2152391720
2440 Q96I24 FUBP3 -0.2383924291 1.050097e-02 0.0602492565
2441 Q16629 SRSF7 1.2595757422 6.354545e-08 0.0612927978
2442 Q8WW59 SPRYD4 -0.1128651061 6.829595e-01 0.0841171863
2443 Q8WUP2 FBLIM1 0.5717179577 4.491768e-03 -0.3000307376
2444 Q9UFN0 NIPSNAP3A 0.1752720862 6.361333e-01 0.0829878556
2445 P18887 XRCC1 0.7302841694 3.552244e-05 0.2159481018
2446 Q15118 PDK1 0.8146132774 1.484807e-01 -0.1283095144
2447 Q9Y5X1 SNX9 0.2038400227 1.074654e-01 -0.2385094504
2448 Q92804 TAF15 0.0903404643 6.038390e-01 0.0767138242
2449 O94826 TOMM70 0.2108903696 1.558634e-01 0.0614062043
2450 Q9BT22 ALG1 0.4991754120 1.261137e-01 0.1188140781
2451 Q9BTU6 PI4K2A -0.7877622293 8.846913e-06 -0.1206832245
2452 O75489 NDUFS3 0.2345735640 4.628069e-01 0.0619173253
2453 P04899 GNAI2 0.8901251476 2.304169e-05 0.0562996012
2454 Q9UKL0 RCOR1 -0.4830987671 2.121440e-03 -0.1213965636
2455 O43237 DYNC1LI2 -0.4810024045 1.562862e-02 0.0930778627
2456 Q9NYU2 UGGT1 0.1535375276 5.078204e-01 0.0707409224
2457 P09471 GNAO1 1.4284544938 4.120712e-02 -0.3247831088
2458 Q9Y2G3 ATP11B -0.0687453930 7.528601e-01 0.1444940203
2459 P84243 H3-3B -1.5299856374 1.967564e-08 0.0855893319
2460 P84243 H3-3A -0.8451934983 9.458782e-06 0.0855893319
2461 Q01995 TAGLN 0.7038730596 2.736851e-01 0.0742650185
2462 O75600 GCAT 0.6727060803 4.996000e-04 0.1441389849
2463 Q9HCN8 SDF2L1 0.6745502609 6.661735e-02 -0.1299348778
2464 Q9Y2G5 POFUT2 0.0653514999 8.314755e-01 -0.1205426272
2465 Q96GW9 MARS2 0.5568052163 2.809161e-02 0.1340874103
2466 Q9H1U9 SLC25A51 -0.0798470763 7.289997e-01 0.2583978467
2467 Q9Y2C4 EXOG 1.1113055777 4.340975e-06 0.1445189602
2468 P08729 KRT7 -1.0801937457 4.287329e-01 -0.3305501575
2469 P48681 NES 0.9081946152 4.814416e-05 0.0796570446
2470 P19634 SLC9A1 -2.0830189739 4.574836e-10 -0.0886286246
2471 Q92769 HDAC2 -0.3786520640 1.554878e-02 -0.0541289871
2472 Q92536 SLC7A6 -0.0295804145 9.345997e-01 -0.1004231165
2473 P05783 KRT18 0.8829370736 2.728087e-02 0.1288285946
2474 Q9HBR0 SLC38A10 -0.2054667644 3.267505e-01 -0.1495131227
2475 P55010 EIF5 -0.7255456588 3.516704e-06 -0.1105096109
2476 Q96HV5 TMEM41A -1.3469975421 2.551398e-07 -0.2174351445
2477 Q9UNF1 MAGED2 -0.0957153952 5.526410e-01 0.1901594665
2478 Q9BYG3 NIFK 0.0537970296 7.947659e-01 -0.0978764034
2479 P67775 PPP2CA -0.0423444468 8.083169e-01 -0.0749985487
2480 P60709 ACTB 1.1911733904 1.401556e-01 0.1634659964
2481 Q13131 PRKAA1 0.1296500008 2.167016e-01 -0.1357777971
2482 Q8IYQ7 THNSL1 -0.7286837089 2.167999e-06 0.0875681758
2483 O60493 SNX3 0.3991619387 9.883046e-02 -0.1144799855
2484 P31040 SDHA -0.2526259768 1.385651e-01 0.0558060876
2485 Q9H5K3 POMK 0.1578527482 7.635140e-01 0.1805844137
2486 P50479 PDLIM4 -1.2100168591 3.035880e-03 -0.1577712949
2487 Q9H061 TMEM126A 0.7792589366 1.141553e-02 0.0779471456
2488 Q16527 CSRP2 0.1250032734 6.021855e-01 0.2286784808
2489 P21127 CDK11B -0.0235672707 9.112240e-01 0.1627577810
2490 Q96K37 SLC35E1 0.1096222361 5.222702e-01 -0.1089010353
2491 Q9NQ55 PPAN 0.5854203463 1.361376e-02 -0.0892782974
2492 P62834 RAP1A -0.2678312595 1.136761e-01 0.0578455041
2493 Q9C0E8 LNPK 0.8951907119 8.678073e-05 0.0550928263
2494 Q9Y375 NDUFAF1 0.0915894425 5.412275e-01 0.0734868250
2495 Q8N138 ORMDL3 0.0062261328 9.855048e-01 0.0789106195
2496 Q5VIR6 VPS53 -0.3552433128 1.079929e-02 -0.2099405738
2497 P98194 ATP2C1 0.5343361766 1.338103e-01 -0.1257401496
2498 P43897 TSFM 0.3252331428 1.126874e-01 -0.0751401884
2499 Q9H8H3 METTL7A -0.7904047700 4.045716e-02 0.2242387378
2500 Q9Y5F9 PCDHGB6 0.6461228342 4.735124e-02 0.1129622774
2501 O14734 ACOT8 -0.2436383717 1.284014e-01 0.1129221016
2502 Q16891 IMMT 0.5224613214 1.933882e-03 0.0560931318
2503 Q8NCC3 PLA2G15 -0.8859299390 6.473601e-03 0.0497102537
2504 P05106 ITGB3 0.7443954844 1.543798e-01 0.0778740923
2505 P53370 NUDT6 0.4598502798 3.157219e-01 -0.1040273457
2506 Q9NSE4 IARS2 0.0250475764 8.634162e-01 0.0493371209
2507 P35611 ADD1 0.1515286412 4.311913e-01 0.0631656805
2508 Q9H479 FN3K 1.4720558600 4.565326e-05 -0.0787604221
2509 Q9Y584 TIMM22 -0.0199925200 9.023055e-01 -0.0652351852
2510 Q8WUM0 NUP133 0.5263330289 3.070939e-08 0.0557621505
2511 Q08211 DHX9 0.1048349930 4.404153e-01 0.0499441591
2512 O75608 LYPLA1 0.5139354865 6.682146e-03 -0.0745766017
2513 Q969S9 GFM2 -0.1654798434 4.223064e-01 0.0627647987
2514 Q7Z2K6 ERMP1 0.3622874046 9.257619e-02 -0.0548550915
2515 Q9UBV2 SEL1L 0.3718793581 6.370818e-02 -0.1622552518
2516 Q13797 ITGA9 0.1553046783 8.118748e-01 -0.2519755185
2517 Q8WZ42 TTN 1.5503118991 1.548083e-03 0.0794226318
2518 O14964 HGS -0.3479797435 3.814316e-03 0.0820228802
2519 Q9NRZ7 AGPAT3 1.3129524979 6.851935e-09 0.1647658519
2520 Q5VWZ2 LYPLAL1 -0.0273748120 9.436764e-01 0.0735450958
2521 P54296 MYOM2 1.5783967642 2.917550e-01 0.2667490413
2522 P22033 MMUT 0.6045395885 2.020883e-04 -0.0479088336
2523 O75340 PDCD6 -0.7721646252 3.484750e-08 0.0963472520
2524 O15347 HMGB3 0.0292633899 8.987883e-01 -0.1528647031
2525 O60437 PPL -0.5370936912 9.853099e-02 -0.0992150100
2526 Q86VF7 NRAP 2.0533013326 8.793317e-02 -0.1724454292
2527 Q9UJ14 GGT7 0.5518019154 1.800319e-01 -0.1841651940
2528 Q14126 DSG2 -0.2950398271 2.745787e-01 0.0906490385
2529 Q9Y305 ACOT9 0.4473976546 9.166317e-02 0.0817539898
2530 O14681 EI24 -2.0223453547 1.700569e-15 0.0504328211
2531 Q96L92 SNX27 -0.2770092005 3.454181e-02 -0.0705107713
2532 Q16643 DBN1 1.1371670784 4.013151e-05 0.1143371074
2533 P08648 ITGA5 0.4052198196 2.276024e-01 0.0524227625
2534 Q16740 CLPP 0.5735338690 2.478798e-04 -0.1587609777
2535 Q9UKV8 AGO2 0.2153615252 2.492656e-01 -0.1227335619
2536 O60443 GSDME -1.1530519198 3.116827e-02 0.0673076311
2537 Q8IZL8 PELP1 -0.0692630422 6.170311e-01 -0.0510384229
2538 Q15262 PTPRK 0.5173309033 3.138572e-03 -0.0921836037
2539 P17405 SMPD1 -0.0446406350 8.815904e-01 -0.0985026308
2540 P06280 GLA -1.0809752169 7.218259e-04 -0.6437860755
2541 Q96AG3 SLC25A46 0.2054926854 2.743544e-01 0.0708928605
2542 P40616 ARL1 0.1872647105 2.107712e-01 -0.0838050306
2543 Q9Y5M8 SRPRB 1.4256986965 3.557126e-05 0.0726368661
2544 O95202 LETM1 0.8533270403 3.412074e-05 0.0636825497
2545 Q8N4Q0 PTGR3 0.0837654112 7.135981e-01 0.0761522567
2546 Q6NVY1 HIBCH -1.0351287184 1.887305e-04 0.0922761288
2547 Q96QR8 PURB 0.0801388864 6.079252e-01 -0.0655748310
2548 O14818 PSMA7 0.7813855124 2.740252e-04 0.0581191834
2549 Q86TX2 ACOT1 -0.2123781167 6.692364e-01 0.1315817143
2550 Q9BRR6 ADPGK 0.2268054422 3.644632e-01 0.1056158330
2551 O14967 CLGN 0.4097482788 2.562461e-01 0.0707776703
2552 Q8IYB3 SRRM1 0.3680207351 4.183113e-02 -0.0414084075
2553 Q96BR5 COA7 0.2017047247 1.890797e-01 -0.0518231100
2554 Q13574 DGKZ -0.5074002197 1.607816e-03 -0.3396388305
2555 P10515 DLAT 1.6015165667 1.176204e-09 0.0508710536
2556 Q96HY7 DHTKD1 0.5985503520 6.565498e-04 -0.0529012086
2557 O14548 COX7A2L -0.3528133514 6.966400e-02 -0.0806063366
2558 Q9H5Q4 TFB2M 0.4670297498 2.600783e-02 0.1169364628
2559 Q92922 SMARCC1 0.0934443982 7.049648e-01 -0.0854619480
2560 Q9UBH6 XPR1 -1.4167253053 7.564749e-06 -0.1026575628
2561 Q9NZL9 MAT2B -0.3424379218 4.381741e-03 0.0814487887
2562 Q9NVJ2 ARL8B -0.8362189775 6.131492e-08 0.0652141143
2563 Q9GZM5 YIPF3 -0.1492491534 3.275521e-01 -0.0734036437
2564 Q5SNT2 TMEM201 0.3870492789 2.320300e-02 0.0535184450
2565 O95487 SEC24B -0.1592382477 1.990496e-01 -0.1845001171
2566 Q9H330 TMEM245 -0.0988973725 6.661304e-01 0.0432196652
2567 Q96RP9 GFM1 0.2436572748 1.876704e-01 0.0594675096
2568 P05067 APP 0.0152687436 9.489411e-01 0.1316403122
2569 Q9BWH2 FUNDC2 0.0606475663 8.170769e-01 0.0656759520
2570 Q9NX20 MRPL16 0.9064266818 2.849637e-05 0.0633923043
2571 P14324 FDPS 0.1416346638 6.142191e-01 -0.1189814702
2572 Q8N183 NDUFAF2 0.1511105735 5.099439e-01 -0.3719138913
2573 Q5BJH7 YIF1B 1.4253199703 3.019843e-06 -0.0547789758
2574 O15439 ABCC4 0.0407828947 9.190308e-01 0.0771259883
2575 Q00577 PURA 0.0127208563 9.609405e-01 0.0583589862
2576 Q9Y6W5 WASF2 -0.2199023452 2.402674e-01 0.1141249087
2577 P50443 SLC26A2 -1.3479890063 3.766949e-03 0.1592965558
2578 Q8TED1 GPX8 3.0484685694 1.554146e-13 -0.0735621163
2579 O95292 VAPB -0.1094827710 4.378143e-01 0.0529490794
2580 Q13155 AIMP2 0.5819064719 1.422933e-03 -0.0727988731
2581 Q9NSC5 HOMER3 -0.3354888628 1.148090e-01 0.1150353643
2582 O75964 ATP5MG -0.0493905276 8.902135e-01 0.0555807615
2583 Q9H0U3 MAGT1 0.3562946865 2.173729e-01 0.0633195394
2584 P00338 LDHA 1.0587934995 2.409196e-01 0.1281426199
2585 Q9H583 HEATR1 0.3391123324 1.867005e-01 0.1074838635
2586 P16435 POR -1.2655279567 1.190999e-06 0.0649701875
2587 Q9Y289 SLC5A6 0.1885906139 4.560770e-01 0.1127788448
2588 Q14156 EFR3A 0.2685704152 2.857056e-01 0.0698061455
2589 O00203 AP3B1 0.0914340384 4.652111e-01 0.0609040878
2590 P78406 RAE1 -0.3100844999 9.315030e-03 0.0640348902
2591 Q9UMR2 DDX19B 0.0014752820 9.908899e-01 -0.0840773046
2592 P61812 TGFB2 -0.5931954178 9.720795e-02 -0.2186484648
2593 Q86SF2 GALNT7 -0.1966649504 7.484510e-01 -0.1319875469
2594 P55072 VCP -0.0419526871 7.709822e-01 -0.0484511095
2595 P14735 IDE 0.6256251410 1.614125e-06 -0.1009494947
2596 O75494 SRSF10 0.5445494331 1.857462e-04 -0.0958188961
2597 Q9UQ90 SPG7 0.3105730123 5.316283e-02 -0.0628197679
2598 O14617 AP3D1 -0.4318239693 3.673295e-03 0.0785024751
2599 P78527 PRKDC 0.2782599456 1.202798e-01 0.0423821780
2600 Q08378 GOLGA3 -0.4409489163 1.087242e-02 0.0851271048
2601 Q8WXI4 ACOT11 1.4115676530 6.509022e-07 0.0780277235
2602 P41091 EIF2S3 0.1812784296 2.685841e-01 -0.0506670771
2603 Q13526 PIN1 -0.3255357436 4.916231e-02 0.0955737571
2604 Q9UI10 EIF2B4 0.3601553688 9.562356e-04 0.2355937702
2605 P05026 ATP1B1 0.2768670516 3.258210e-01 -0.0436296616
2606 O60518 RANBP6 0.0480501091 8.732040e-01 -0.1015523148
2607 Q9H845 ACAD9 0.1266353329 1.610315e-01 0.0554651052
2608 A6NK58 LIPT2 0.1309436026 7.460294e-01 0.0661541060
2609 Q3ZCQ8 TIMM50 0.5117820878 2.736684e-04 0.0582774510
2610 Q9HCH3 CPNE5 -0.2321974841 4.828487e-01 -0.1007581731
2611 O75880 SCO1 0.0842102825 6.119409e-01 0.0590593941
2612 Q10469 MGAT2 0.1004830131 5.478646e-01 0.0690940739
2613 P82650 MRPS22 0.2482159660 2.379069e-01 0.0534350875
2614 Q9H078 CLPB 1.0532811603 6.131492e-08 -0.0899252875
2615 Q9UJY1 HSPB8 -1.0598526509 3.307007e-06 -0.0805324053
2616 Q9UH62 ARMCX3 -0.4069138156 1.286143e-02 -0.0958888585
2617 Q8WU76 SCFD2 1.5317503551 2.385808e-05 -0.0840733440
2618 Q2TAA2 IAH1 0.6672248678 7.584923e-02 -0.1699194872
2619 P98175 RBM10 0.3394993051 8.940688e-03 -0.0732169941
2620 Q9NPA0 EMC7 -0.3903013917 3.918018e-02 0.0652774520
2621 Q12931 TRAP1 0.7068623097 2.162977e-06 0.0574071475
2622 P10599 TXN -0.4839048918 1.833892e-01 -0.0676638518
2623 Q13200 PSMD2 -0.2148143779 1.783229e-01 0.0475088875
2624 P83111 LACTB -0.2707482119 3.348552e-02 0.0705257544
2625 P05023 ATP1A1 -0.0995814694 6.895934e-01 0.0403098199
2626 Q6PI48 DARS2 0.6837442563 3.079227e-06 0.0626504584
2627 O43809 NUDT21 0.4052185510 2.138124e-03 -0.1246001420
2628 Q99986 VRK1 0.7325617825 3.881177e-02 0.3203400277
2629 Q9Y6X4 FAM169A 0.6938112613 3.995721e-03 0.0592569582
2630 O43324 EEF1E1 0.9867779144 5.131606e-04 -0.1899648976
2631 P48509 CD151 0.1635675502 4.784343e-01 0.0842260211
2632 P35052 GPC1 -0.0879123208 6.383740e-01 -0.1470547036
2633 Q9NZ45 CISD1 0.4159239357 2.132812e-01 -0.0567521175
2634 Q16563 SYPL1 0.3795805055 8.407325e-03 0.1345546282
2635 Q9Y3D6 FIS1 0.3357572162 1.861721e-01 -0.1104808456
2636 D6RIA3 C4orf54 -1.7968489000 2.496839e-04 -0.1081073911
2637 Q05639 EEF1A2 1.6832224831 1.848845e-07 0.0832158192
2638 Q15056 EIF4H -0.6116727151 1.151303e-06 0.0854103602
2639 O75648 TRMU 0.8604649782 1.067794e-04 0.0607986277
2640 Q6PIF6 MYO7B 0.8429421466 1.387979e-01 -0.0828737441
2641 P62879 GNB2 -0.1653011337 2.851546e-01 -0.0485644451
2642 Q9NRG7 SDR39U1 0.2985167008 1.985132e-01 -0.1430473443
2643 Q99735 MGST2 -0.1700401697 5.268783e-01 -0.0558466744
2644 Q07954 LRP1 -0.3349441725 3.537431e-01 -0.0723738317
2645 P54578 USP14 0.2514016694 7.706288e-02 -0.0916852238
2646 Q01974 ROR2 1.2672147544 9.680216e-03 -0.0722757987
2647 Q9NQH7 XPNPEP3 0.0530862921 7.377871e-01 -0.0657496183
2648 Q14160 SCRIB -0.6435861716 5.474390e-04 0.0615592583
2649 Q9UI43 MRM2 -0.4076633948 1.818576e-03 -0.0707575688
2650 P17540 CKMT2 0.3580122056 5.176419e-01 0.0504446365
2651 Q99538 LGMN -0.4976071817 2.054690e-01 0.1282354493
2652 O15049 N4BP3 0.4215966539 1.420118e-01 0.0837154845
2653 Q9H920 RNF121 0.1502067048 3.629881e-01 -0.0500147316
2654 Q9Y5S9 RBM8A -0.2469778184 1.716700e-02 -0.0998954406
2655 Q96KP4 CNDP2 0.6598520480 4.018998e-04 0.0930430190
2656 Q5HYI7 MTX3 -0.5461515008 9.301754e-05 -0.1275601756
2657 P98196 ATP11A 0.6328987985 7.387914e-04 0.1411533919
2658 Q96AB3 ISOC2 1.0831514061 3.552244e-05 -0.0773212472
2659 Q8N128 FAM177A1 -0.2268155265 2.248883e-01 0.0706439264
2660 Q9BYD2 MRPL9 0.1396258467 5.212238e-01 -0.0492047624
2661 Q6WCQ1 MPRIP -0.7807004684 1.126835e-06 -0.1613623152
2662 O95782 AP2A1 -0.0097067352 9.391114e-01 0.0457570291
2663 Q96JB5 CDK5RAP3 -0.5245609230 5.048248e-04 -0.0546585614
2664 Q9NRC6 SPTBN5 0.5077932744 3.365473e-01 -0.1027994903
2665 Q92974 ARHGEF2 0.7632771201 3.678876e-06 -0.1406441587
2666 Q96N67 DOCK7 0.0611686180 6.506806e-01 0.0721885534
2667 Q9UQM7 CAMK2A -0.5609558277 2.435398e-01 -0.0582152129
2668 P16949 STMN1 0.3835150936 8.016840e-02 -0.1363541714
2669 P10620 MGST1 0.7336422732 6.965271e-02 -0.0648036547
2670 Q9Y383 LUC7L2 -0.0364676557 8.966021e-01 -0.0508557701
2671 P46940 IQGAP1 -1.0625544249 1.057504e-01 -0.1615421363
2672 P07686 HEXB -0.3352275762 3.900074e-01 0.0476819765
2673 Q5T653 MRPL2 0.4129304291 1.076757e-01 0.0659755779
2674 Q70CQ2 USP34 0.4087772356 4.361926e-04 0.0599315830
2675 P32322 PYCR1 1.5524154653 1.103013e-08 0.0586004526
2676 Q9P016 THYN1 0.6238648553 9.355885e-04 -0.0942341510
2677 O95772 STARD3NL 0.6361316416 1.547445e-03 -0.1393674627
2678 Q9NVI7 ATAD3A 1.3949761759 8.073924e-13 0.0492057469
2679 Q9UIG8 SLCO3A1 1.2094959376 2.321652e-08 -0.1126949802
2680 Q6UVY6 MOXD1 -0.0134253435 9.902724e-01 0.2286318734
2681 O95807 TMEM50A -0.0549467221 7.754355e-01 0.0619011946
2682 Q9NQX4 MYO5C 0.8751175315 7.295568e-02 0.1939865053
2683 Q96HE7 ERO1A 0.5832648632 1.311261e-01 -0.0658820362
2684 Q9Y2D5 PALM2AKAP2 1.5083646100 2.554631e-04 -0.0560915416
2685 P36957 DLST -0.0777303111 5.022038e-01 0.0488353820
2686 Q9NWU5 MRPL22 0.4324154719 1.720433e-02 0.0763464017
2687 Q9NWU1 OXSM -0.0799563404 8.151385e-01 0.2012832619
2688 Q01650 SLC7A5 -0.7509730942 2.103451e-01 0.1411293422
2689 Q9Y2Z9 COQ6 -0.3303364544 2.087049e-02 -0.0833031421
2690 P27816 MAP4 -0.0111065627 9.705725e-01 0.0922741439
2691 P07225 PROS1 -0.0971194305 6.101213e-01 -0.0965151172
2692 Q9NUJ1 ABHD10 0.9066565276 2.461916e-04 -0.0587708345
2693 P32418 SLC8A1 3.1835431479 4.769101e-09 0.0452835669
2694 Q9NP72 RAB18 -0.3874919938 2.647971e-03 -0.0887283708
2695 Q9NVV4 MTPAP 0.4799515097 2.349367e-03 0.1146156235
2696 P08754 GNAI3 -0.3409940351 2.232265e-01 -0.0781616066
2697 O43760 SYNGR2 -0.0342205186 8.815993e-01 0.0756914626
2698 P17812 CTPS1 -1.1167805358 7.091370e-03 0.0835420863
2699 O75152 ZC3H11A 0.0624688295 6.256821e-01 0.1437682787
2700 P20810 CAST -0.0714795511 6.765701e-01 -0.0818775766
2701 Q7L3T8 PARS2 -0.1565213656 4.748472e-01 0.0663663904
2702 Q86WU2 LDHD 0.7281306332 3.067223e-02 -0.1427661689
2703 Q14738 PPP2R5D -0.1121890011 4.876574e-01 -0.1247885566
2704 P57088 TMEM33 0.1295374324 4.195866e-01 -0.0383958437
2705 O95249 GOSR1 -0.0449952471 7.442568e-01 -0.2318964369
2706 Q2PZI1 DPY19L1 -0.3295427484 1.864519e-01 0.0545807289
2707 Q13454 TUSC3 -0.2052341348 2.053194e-01 0.0811115859
2708 P63261 ACTG1 0.9124379264 2.017725e-01 0.1514098541
2709 Q9UBS9 SUCO -1.1114626973 7.774826e-08 -0.0588708025
2710 P08195 SLC3A2 -0.8988803890 3.124818e-02 0.0999257085
2711 O00299 CLIC1 0.8938427485 5.660302e-03 -0.0478113576
2712 O75298 RTN2 1.1554884367 2.486770e-04 0.0659977777
2713 Q04837 SSBP1 0.1737329458 2.162510e-01 0.0373694231
2714 Q13618 CUL3 -0.2401622985 6.957132e-02 -0.1004011916
2715 Q9BXK5 BCL2L13 -0.1482820028 1.521714e-01 0.0521963085
2716 P21333 FLNA -1.0136720766 1.202798e-01 0.1265936731
2717 P14415 ATP1B2 1.0374333676 7.894786e-03 0.1662601308
2718 Q8IYS2 KIAA2013 -0.4848078958 1.193138e-04 0.0395207619
2719 Q8N6T3 ARFGAP1 -0.9167574926 2.259300e-06 0.1125089163
2720 P53618 COPB1 0.3977257043 4.226960e-02 -0.0497748823
2721 Q96BM9 ARL8A -0.9854771003 4.190086e-10 0.0767938406
2722 Q9P0K7 RAI14 0.8155768340 1.994095e-03 0.0693240416
2723 Q9HAV0 GNB4 0.9868231804 7.083006e-05 0.1343798366
2724 Q96TA2 YME1L1 -0.2137780535 9.744620e-02 -0.0439313764
2725 O00469 PLOD2 0.3939850317 1.365480e-01 -0.0665084542
2726 Q13404 UBE2V1 -0.0007615578 9.982756e-01 0.0468917361
2727 Q10713 PMPCA -0.5635984037 2.499798e-05 0.0550121724
2728 Q9NZM1 MYOF 0.2590918498 7.374383e-01 0.0598254527
2729 P08236 GUSB 0.2294336255 1.048175e-01 0.0523026752
2730 P17900 GM2A -0.3534298821 3.298585e-01 -0.0714124070
2731 O75116 ROCK2 0.1529708576 3.931930e-01 -0.2522418974
2732 Q9UBS4 DNAJB11 -0.1192728397 6.626186e-01 0.0511029395
2733 P49736 MCM2 2.5137351365 1.527253e-10 -0.1170023987
2734 P57679 EVC 0.2274242440 5.590541e-01 -0.1775980741
2735 P46013 MKI67 3.1925555339 4.277678e-09 -0.0818400961
2736 Q96TC7 RMDN3 -0.4889222680 8.230405e-02 0.0592588068
2737 Q5J8M3 EMC4 -0.0571915661 7.186727e-01 0.0322312379
2738 Q6NZI2 CAVIN1 -0.4143890508 9.599098e-02 -0.0581681850
2739 O43447 PPIH 1.1325713088 3.903568e-07 -0.0539035288
2740 Q9HCU5 PREB -0.3227376633 5.862226e-03 -0.0510941370
2741 P49591 SARS1 -1.0527251109 1.577502e-08 0.1073736212
2742 Q15125 EBP 0.4399490328 6.579634e-02 0.0435468627
2743 P40763 STAT3 -1.0243533136 2.139961e-05 0.0447656245
2744 P13611 VCAN 0.1345961284 7.373560e-01 -0.0508078233
2745 P19022 CDH2 1.0229789347 3.472860e-06 -0.0519210903
2746 Q7Z333 SETX 0.2847320717 1.284597e-01 -0.1004294542
2747 Q9NZC3 GDE1 -0.3856784333 4.123132e-02 0.0570080442
2748 Q13424 SNTA1 0.3364184108 4.081515e-01 0.0412656794
2749 Q9H2V7 SPNS1 -0.1917477773 3.157111e-01 -0.0635085952
2750 Q5SWX8 ODR4 0.1316054818 3.830812e-01 0.0953584047
2751 P11169 SLC2A3 0.3337652162 3.138746e-01 -0.1080010260
2752 Q15942 ZYX -0.0014679632 9.962108e-01 0.0622000068
2753 Q86WV6 STING1 -0.8053645358 8.061501e-02 0.1072970854
2754 P48449 LSS 0.8975821584 3.491184e-06 0.0356129336
2755 Q9BV73 CEP250 -0.3598995582 1.506746e-01 -0.0596036872
2756 Q92782 DPF1 1.9951502499 7.472775e-08 0.0576145448
2757 Q13033 STRN3 -0.0690902368 7.368047e-01 0.0352323755
2758 P17301 ITGA2 -0.6592482313 3.355090e-01 0.1003710135
2759 Q15293 RCN1 0.0734770925 8.662738e-01 0.0628197111
2760 P53701 HCCS -0.0867614590 5.480628e-01 -0.0484273888
2761 Q9UKS6 PACSIN3 -0.5272179865 8.845802e-02 -0.1094987063
2762 Q07955 SRSF1 1.1467374695 5.346559e-07 -0.0391859015
2763 Q7L592 NDUFAF7 -0.2633960486 1.182386e-01 -0.0404932725
2764 P33316 DUT 0.6312258784 3.413888e-02 0.0774810686
2765 Q05519 SRSF11 0.1190336337 4.799253e-01 0.0569071921
2766 Q9UNZ2 NSFL1C 0.2955679637 1.963230e-02 0.0592351024
2767 O95208 EPN2 0.3143992197 1.025879e-01 0.0382845970
2768 Q99615 DNAJC7 0.3290536994 3.051566e-03 -0.0676349976
2769 P11217 PYGM 1.1700866775 4.925563e-04 0.0598227514
2770 Q8N1G2 CMTR1 0.1603182047 1.682034e-01 0.0819301533
2771 O75306 NDUFS2 0.2880903396 1.178153e-01 0.0399446084
2772 Q99426 TBCB 0.6548047592 7.473858e-04 0.0986086617
2773 Q5W111 SPRYD7 -0.4229806633 2.582381e-04 -0.0523072823
2774 Q9NP81 SARS2 1.0214661726 4.101962e-06 -0.0444664870
2775 Q9HDC5 JPH1 -0.1280236647 6.192886e-01 0.2317496612
2776 Q9UJC3 HOOK1 1.1753749079 8.509754e-04 0.0940526189
2777 Q92506 HSD17B8 -0.3905828587 1.022885e-01 -0.0712989662
2778 P11234 RALB -1.0172204118 7.529379e-07 -0.0403100190
2779 Q99623 PHB2 0.5099329422 1.705015e-03 -0.0514729501
2780 P53985 SLC16A1 0.5892047325 7.591981e-02 0.0438739194
2781 P55795 HNRNPH2 -0.1209912621 6.382475e-01 0.0350025774
2782 O14974 PPP1R12A -0.0877030419 6.815455e-01 0.0453489137
2783 P09936 UCHL1 -0.3399545366 6.273533e-01 0.0904408042
2784 Q96KP1 EXOC2 0.4330945960 1.761561e-02 0.0945528203
2785 P30040 ERP29 0.0508678515 8.112169e-01 -0.0465198501
2786 Q96EP5 DAZAP1 0.7609342008 2.812139e-06 -0.0369992686
2787 Q9P0I2 EMC3 -0.2996132352 6.588620e-02 0.0366126282
2788 Q9Y235 APOBEC2 -0.9052056042 1.473419e-01 0.0583786774
2789 O15400 STX7 0.3354591695 3.350851e-02 -0.0344998618
2790 Q13144 EIF2B5 0.2531519590 3.449055e-02 0.0433398568
2791 O75147 OBSL1 0.4335231822 1.971177e-01 0.0577891854
2792 Q12789 GTF3C1 -0.2615329182 3.133200e-01 -0.0640506438
2793 P42167 TMPO 0.7237111156 1.412195e-03 -0.0375140209
2794 O00231 PSMD11 0.1317317300 4.084242e-01 0.0375918482
2795 Q9Y3D2 MSRB2 -0.0517416376 8.738745e-01 0.0586541092
2796 Q8IVS2 MCAT -0.2926567365 9.613072e-02 -0.1014839470
2797 Q9H3H5 DPAGT1 0.4086802317 1.157844e-01 0.0427259471
2798 Q5TGZ0 MICOS10 0.1068775129 6.606668e-01 -0.0447177365
2799 Q8N5N7 MRPL50 0.2385118249 1.950985e-01 0.0925113632
2800 P42166 TMPO 0.7237111156 1.412195e-03 0.0630164041
2801 P62318 SNRPD3 0.2561489101 1.719657e-02 0.1150055434
2802 P35222 CTNNB1 -0.3135098953 5.573547e-02 0.0446602174
2803 Q9UM22 EPDR1 -0.1849868484 6.122030e-01 0.0881448434
2804 P21912 SDHB 0.5052465843 4.003952e-02 0.0336121763
2805 P61106 RAB14 -0.6061920095 6.679032e-06 -0.0482372598
2806 Q9BWS9 CHID1 0.0771900662 6.203558e-01 0.0553802355
2807 Q9UL25 RAB21 -0.5980758710 1.749916e-03 -0.0353052471
2808 Q8NDY3 ADPRHL1 1.6004304321 1.136792e-04 0.0537533243
2809 Q9Y4W6 AFG3L2 0.9546075105 3.305842e-09 0.0341604126
2810 Q9NQC3 RTN4 0.4550297070 5.150134e-03 -0.0482728158
2811 Q9H074 PAIP1 0.4366179687 4.251179e-04 -0.1140952414
2812 Q10471 GALNT2 -0.2016125277 6.685165e-01 0.0649653054
2813 Q9BPW8 NIPSNAP1 0.9220238580 1.273560e-03 -0.0384468594
2814 Q9HC36 MRM3 0.3965624087 4.552754e-02 0.0546904084
2815 P52292 KPNA2 0.8046923564 1.648005e-04 0.0497956870
2816 P15586 GNS -0.2958473758 2.518025e-01 0.0306316731
2817 O75352 MPDU1 0.3227422935 2.134996e-01 0.0468059691
2818 O15061 SYNM -1.1301308435 1.964901e-06 -0.0817377103
2819 Q9Y6K0 CEPT1 -0.7299724718 7.499442e-05 -0.0787014303
2820 P08069 IGF1R -0.7116650541 3.449183e-04 -0.0689514183
2821 O00562 PITPNM1 -0.2555296692 4.094867e-01 0.1285049043
2822 Q14978 NOLC1 0.0941669401 6.831750e-01 -0.0428509657
2823 Q9H9P8 L2HGDH 1.1148373528 2.186165e-07 0.0587676775
2824 Q9UIW2 PLXNA1 0.5527794006 3.662538e-02 -0.0387004284
2825 Q8NHH9 ATL2 0.2186443478 2.227770e-01 -0.0547411172
2826 Q9BV38 WDR18 1.0320014546 9.827105e-05 -0.0477595397
2827 P52948 NUP98 0.4585014024 1.016122e-04 -0.0377301892
2828 Q7Z4V5 HDGFL2 -0.0309362072 8.351643e-01 0.0444152867
2829 Q9UMS6 SYNPO2 2.0191382577 8.842194e-04 0.0762101842
2830 Q8NE86 MCU 0.0919034848 7.318300e-01 -0.0610622846
2831 O14828 SCAMP3 0.8991398890 6.266594e-06 -0.0586641523
2832 Q15382 RHEB -0.3164275823 9.554793e-02 0.0980563155
2833 Q9H0Q3 FXYD6 0.8701441681 2.026593e-01 -0.0890873295
2834 Q9UPN6 SCAF8 -0.1929916183 2.928622e-01 0.0757156842
2835 P38435 GGCX -0.1847947804 4.394869e-01 -0.0977452700
2836 P04844 RPN2 -0.1306212037 5.687116e-01 0.0382036593
2837 O75923 DYSF 1.1621227104 1.600570e-06 0.0384468794
2838 P43307 SSR1 0.2111926133 5.063750e-01 -0.0386476726
2839 P48426 PIP4K2A -1.0699081860 2.290935e-05 0.0815168067
2840 P49903 SEPHS1 0.4702161666 2.673273e-04 0.0766595914
2841 Q86SX6 GLRX5 0.2013957932 2.053194e-01 -0.0952910019
2842 P54727 RAD23B 0.0633134843 6.185586e-01 0.0349093765
2843 Q96C01 FAM136A 0.6096478093 1.314144e-03 -0.0467326244
2844 P12081 HARS1 0.1437977121 4.130152e-01 -0.0453891068
2845 Q9H6X2 ANTXR1 0.0498977738 8.443521e-01 -0.0920511319
2846 Q9Y672 ALG6 0.4433937328 1.714454e-01 0.1066017201
2847 Q7Z3D6 DGLUCY 0.9247290692 1.051245e-03 -0.2631853628
2848 Q12841 FSTL1 -0.0010329937 9.984980e-01 -0.0922538851
2849 P68036 UBE2L3 -0.0134667438 9.082355e-01 0.0570999245
2850 Q9NVV0 TMEM38B 0.2517104597 5.219035e-01 -0.0675819583
2851 Q6UW02 CYP20A1 -0.0644544560 6.820543e-01 -0.1041480335
2852 P46379 BAG6 0.3581078598 5.985753e-03 -0.0524820295
2853 P50991 CCT4 -0.0156253035 9.285961e-01 0.0517182399
2854 O15427 SLC16A3 0.1013201229 8.698396e-01 -0.0627494545
2855 P49721 PSMB2 0.1736474882 2.222727e-01 -0.0587442742
2856 O95490 ADGRL2 -0.1020226040 6.002582e-01 0.0609834445
2857 P50995 ANXA11 -0.2453330962 4.428612e-01 -0.0623106737
2858 Q9NRD8 DUOX2 -4.1202038448 1.002301e-05 0.0631037482
2859 Q15020 SART3 -0.0625391404 7.398659e-01 0.0429271374
2860 P49590 HARS2 0.4994461191 7.250382e-03 -0.0346749937
2861 Q7KZN9 COX15 -0.2930529375 3.579409e-03 0.0440658440
2862 Q9UHK6 AMACR 1.3043917794 1.797816e-03 -0.0735248336
2863 Q4ZIN3 TMEM259 -0.2273601374 1.977664e-01 0.0535062995
2864 Q96ED9 HOOK2 0.1975435921 6.382631e-01 -0.0590927216
2865 Q5TZA2 CROCC -1.1006844648 5.905056e-03 0.0767071421
2866 Q86TM6 SYVN1 -0.3880618122 1.256510e-01 0.0459224259
2867 P08962 CD63 0.0150629990 9.623440e-01 0.0770717857
2868 Q9UNM6 PSMD13 -0.5066445167 3.723469e-06 0.0316437552
2869 O95363 FARS2 0.5535626148 2.439788e-03 -0.0690304728
2870 Q92581 SLC9A6 0.5113228175 1.388297e-02 0.0702929967
2871 O00161 SNAP23 0.6303111960 6.560196e-02 0.0437024141
2872 P68402 PAFAH1B2 -0.2886264239 1.301005e-01 0.0625850587
2873 Q99797 MIPEP 0.1256705484 4.966359e-01 -0.0511739415
2874 P51571 SSR4 -0.1835340581 3.544101e-01 -0.0441070358
2875 Q7Z460 CLASP1 0.3337851121 8.710299e-02 -0.0518114110
2876 P20338 RAB4A 0.1765960218 3.922651e-01 0.0465858671
2877 Q14241 ELOA -0.4092187949 8.578736e-04 0.0515293974
2878 P25685 DNAJB1 0.0796660234 6.446858e-01 -0.0271807257
2879 Q99733 NAP1L4 -0.3769014802 3.533737e-04 -0.0469481717
2880 P49585 PCYT1A -0.0301102915 8.784290e-01 0.1541059672
2881 Q8N6M3 FITM2 0.9694399260 4.442482e-03 0.0357752799
2882 Q14554 PDIA5 0.0186104793 9.764407e-01 0.0348707433
2883 Q99729 HNRNPAB -0.6763190330 5.374784e-04 0.0409336737
2884 Q9UKR5 ERG28 1.1097841817 1.122309e-06 -0.0962221993
2885 Q6UXH1 CRELD2 -0.0948733189 7.962517e-01 0.0965664343
2886 P12931 SRC -1.3712317108 7.722022e-06 0.0407092704
2887 P08237 PFKM 1.4935116688 1.210313e-06 -0.0898612605
2888 Q01484 ANK2 1.7939950354 8.866739e-09 0.0272193144
2889 Q9NRX4 PHPT1 -0.7349230853 6.783380e-03 0.1202582430
2890 O60488 ACSL4 -0.0552859542 8.688927e-01 0.0473513869
2891 Q9ULH0 KIDINS220 0.2402749428 1.643516e-01 -0.0328930357
2892 P23141 CES1 0.6945623858 8.736288e-01 0.1630179495
2893 Q5T160 RARS2 -0.0981851020 6.179473e-01 0.0919742209
2894 P49419 ALDH7A1 0.2759755526 2.970574e-01 0.0264597337
2895 Q96A35 MRPL24 0.8250328709 1.456717e-05 0.0399831462
2896 Q92879 CELF1 -0.3073608827 2.150925e-02 -0.1024579295
2897 O15127 SCAMP2 0.2396260245 9.852726e-02 -0.0324583556
2898 P24534 EEF1B2 -0.2127318204 1.537205e-01 0.0376215225
2899 Q99714 HSD17B10 -0.0669239898 7.571384e-01 0.0336276297
2900 P33121 ACSL1 -0.6970208124 9.547417e-05 0.0614585272
2901 O75251 NDUFS7 0.3535741567 2.407003e-01 0.0287078657
2902 Q7L311 ARMCX2 1.8973023053 3.327111e-10 0.0481945613
2903 Q9NUL3 STAU2 0.0131930846 9.462116e-01 -0.0377401765
2904 Q99567 NUP88 0.3971294141 1.633437e-03 0.0516413103
2905 Q96S97 MYADM 1.5499982440 4.850498e-08 -0.0294306152
2906 Q53H82 LACTB2 -0.8935615934 1.078156e-06 0.0838942441
2907 P61970 NUTF2 -0.0748784852 6.682603e-01 0.0347417475
2908 Q7KYR7 BTN2A1 0.2873014354 2.533183e-01 -0.0365146529
2909 Q9Y5Y5 PEX16 -0.6684280247 5.083541e-05 -0.0471252563
2910 Q9NX40 OCIAD1 -0.1469789802 3.105960e-01 -0.0329535853
2911 O76041 NEBL 1.3297566443 1.144136e-04 -0.0339931053
2912 Q92785 DPF2 -0.6879058448 5.208639e-04 -0.1388608274
2913 P41250 GARS1 0.8619748361 6.728452e-05 0.0671563567
2914 Q14332 FZD2 1.4730566556 1.199648e-07 -0.0458899048
2915 P21953 BCKDHB 0.3133160340 3.763684e-02 -0.0554461002
2916 Q8WUY8 NAT14 0.8536008659 3.181297e-04 -0.0268740309
2917 Q6UVK1 CSPG4 -2.2982710161 6.625095e-05 0.0655424195
2918 P60903 S100A10 -0.2551527683 6.924834e-01 -0.0458432780
2919 Q6KC79 NIPBL 0.3087974361 1.787737e-02 0.0367659292
2920 Q7KZI7 MARK2 -0.0457171413 7.466869e-01 0.0480489442
2921 O43172 PRPF4 -0.0809936850 6.507105e-01 -0.0372325420
2922 Q8NHP6 MOSPD2 -0.4707672151 1.301717e-01 -0.0877578602
2923 Q86YP4 GATAD2A -0.1701517434 4.384734e-01 -0.0510996736
2924 O60476 MAN1A2 0.3391328573 1.234174e-02 -0.0245294283
2925 O15031 PLXNB2 -0.8812962608 3.598989e-03 -0.0265972718
2926 Q9Y5U8 MPC1 1.5352718248 3.271239e-04 0.0329559961
2927 Q8NFF5 FLAD1 -0.4391096098 1.658847e-03 0.0423090757
2928 Q9BZE1 MRPL37 -0.1088503690 4.340233e-01 -0.0272307953
2929 Q99959 PKP2 0.5908823609 2.229208e-03 -0.0431539448
2930 Q9BY44 EIF2A -0.2529319925 1.090653e-01 -0.0588306792
2931 P51812 RPS6KA3 -0.5160511858 7.178237e-02 -0.1351357707
2932 O60885 BRD4 -0.1896562194 2.819238e-01 -0.0268679220
2933 Q6DD88 ATL3 0.1778359666 7.055532e-01 0.0526935539
2934 Q96T60 PNKP 0.2889479929 5.830660e-03 0.0457296192
2935 P42892 ECE1 -0.7328690188 4.039544e-02 -0.0420162753
2936 Q9NPJ3 ACOT13 0.5659913885 5.808184e-03 -0.0226461076
2937 Q8N442 GUF1 -0.4627736790 2.908206e-03 0.0642603869
2938 Q8IXL7 MSRB3 1.2172022551 3.086585e-08 -0.0556078094
2939 Q6ZT12 UBR3 0.1760618267 4.091701e-01 0.0300423740
2940 Q99808 SLC29A1 0.2987470523 2.640764e-01 0.0874593754
2941 Q9P2I0 CPSF2 0.0571515581 7.962114e-01 -0.0879946763
2942 P28827 PTPRM 0.1917169328 3.458209e-01 -0.0331786696
2943 Q9NVA1 UQCC1 -0.3507511332 1.998292e-02 -0.0340033995
2944 Q9BZG1 RAB34 0.4474600346 1.284409e-02 0.0508239569
2945 Q9Y3E5 PTRH2 0.0012722096 9.951722e-01 0.0645852521
2946 Q9P2K3 RCOR3 0.2524331758 2.221760e-01 0.0392585124
2947 Q99627 COPS8 -0.2659476261 2.590406e-02 0.0349591146
2948 P12956 XRCC6 -0.2232203727 7.866292e-02 -0.0256959162
2949 Q9UHD9 UBQLN2 0.4515462663 6.169912e-03 -0.0272603802
2950 Q16630 CPSF6 0.2000872512 7.758310e-02 -0.0240807929
2951 Q15172 PPP2R5A 0.5067013570 9.406655e-02 0.0631589618
2952 Q13418 ILK 0.9473400948 1.244212e-04 0.0345000810
2953 Q02641 CACNB1 1.9195037129 9.739369e-07 -0.0592226725
2954 Q86WA6 BPHL 0.5707764251 3.152536e-02 -0.0518002257
2955 Q12769 NUP160 0.7710263291 9.436648e-08 0.0406688623
2956 Q14011 CIRBP -1.1407725749 3.107872e-06 -0.0414076139
2957 P08579 SNRPB2 -0.1572061897 2.036525e-01 -0.0391390556
2958 Q9Y6A9 SPCS1 0.1690266648 1.851494e-01 0.0359485719
2959 P32189 GK 0.3606583800 4.827493e-01 0.0433016068
2960 Q9BU61 NDUFAF3 0.1114685464 5.592804e-01 -0.0346113474
2961 Q8NI37 PPTC7 0.0438384796 8.588064e-01 -0.0373320338
2962 O43707 ACTN4 -0.4761080147 4.266202e-01 0.0777883145
2963 P49588 AARS1 1.5841070552 6.467535e-09 0.0890582812
2964 Q15907 RAB11B 0.4795082111 2.439736e-02 0.0257816639
2965 Q9BZE4 GTPBP4 -0.2988125487 3.856018e-02 -0.0498385332
2966 Q96EY7 PTCD3 0.6391311044 1.736612e-03 -0.0248277728
2967 Q96BI1 SLC22A18 1.4737032602 4.801212e-06 -0.0359401402
2968 Q9UBC2 EPS15L1 0.2133944917 1.693419e-01 -0.0279279655
2969 Q96HC4 PDLIM5 1.2523781031 4.023588e-06 -0.0248868539
2970 Q8N2U0 TMEM256 0.6431733357 2.481525e-02 0.0322142413
2971 P50336 PPOX 1.0147511388 1.940429e-05 0.0460942490
2972 P55268 LAMB2 0.2994478987 4.049431e-01 0.0512589339
2973 Q07065 CKAP4 0.2290019241 5.619301e-01 0.0339764070
2974 Q9Y4F5 CEP170B -1.8261592828 1.011517e-09 0.0376916941
2975 P25490 YY1 -0.6359075407 1.642571e-06 0.0898810561
2976 Q15334 LLGL1 -0.5192386417 4.128438e-03 0.0547027133
2977 O75094 SLIT3 1.4134005456 5.792407e-05 -0.1671000127
2978 Q13061 TRDN 0.9233678722 2.516266e-03 -0.0403187385
2979 Q9Y3B3 TMED7 0.0187024262 9.297143e-01 -0.0350062646
2980 Q9BV10 ALG12 0.6429692943 2.560487e-04 0.0327413818
2981 Q9HAU0 PLEKHA5 0.3347440682 2.250581e-01 -0.0266480630
2982 O60831 PRAF2 -0.0151365017 9.621687e-01 -0.0370789890
2983 Q9P253 VPS18 0.0742694706 7.132751e-01 -0.0529451039
2984 P05161 ISG15 -1.5702937459 1.524907e-05 0.0669276535
2985 Q8IUR5 TMTC1 -0.1437311405 7.572866e-01 -0.0396019266
2986 Q5TEU4 NDUFAF5 0.6492995017 6.676116e-03 -0.0289994717
2987 P49720 PSMB3 -0.0288951918 8.800350e-01 0.0293139657
2988 P61803 DAD1 0.4229397466 6.178350e-02 0.0397682481
2989 Q969N2 PIGT -0.2282905765 2.446822e-01 0.0244231043
2990 O95563 MPC2 0.1432933277 7.056427e-01 0.0245607177
2991 Q15796 SMAD2 -0.1048940620 4.897474e-01 0.0533082365
2992 P08574 CYC1 0.6622068989 2.042507e-02 0.0236360400
2993 Q13363 CTBP1 -0.2228051809 1.013186e-01 -0.0282297751
2994 Q96MR6 CFAP57 -1.3049954676 2.723012e-02 -0.0626455125
2995 P05787 KRT8 -0.7728995409 1.526432e-02 0.0401858350
2996 Q14118 DAG1 0.5142330967 3.137162e-03 0.0245662429
2997 Q9UIA9 XPO7 0.6699559639 1.983530e-05 0.0587230586
2998 P48047 ATP5PO 0.9503223957 8.897693e-03 -0.0270509250
2999 Q99523 SORT1 0.5347403952 1.924261e-02 -0.0405566479
3000 P12955 PEPD -0.0952042460 5.809760e-01 -0.2413330960
3001 P35221 CTNNA1 -0.2327434255 1.767331e-01 -0.0226633349
3002 Q9Y2Z4 YARS2 -0.0822160346 5.310203e-01 0.0282054454
3003 Q9NPH0 ACP6 0.8323731478 8.348710e-04 -0.0532582391
3004 Q8TCT9 HM13 -0.2385395131 3.756555e-01 -0.0348934272
3005 Q9BVG9 PTDSS2 0.3333820081 6.978137e-02 -0.0535673994
3006 Q05682 CALD1 -0.2955914500 5.644595e-01 0.0850223075
3007 P51149 RAB7A -0.9730000611 4.807184e-10 0.0233836508
3008 A6NHR9 SMCHD1 0.4262820303 7.151271e-03 -0.0269693090
3009 P29317 EPHA2 -1.6695042973 2.253533e-06 0.0427380340
3010 Q01973 ROR1 1.0458692713 1.745846e-06 0.0332207465
3011 Q16854 DGUOK -0.0663695406 6.878724e-01 -0.0222537186
3012 O00754 MAN2B1 -0.2076259025 3.117371e-01 0.0261289337
3013 P31946 YWHAB -0.2709485083 5.696446e-02 0.0490402257
3014 Q5RI15 COX20 -0.0789223383 8.457300e-01 -0.0429324298
3015 P59998 ARPC4 -0.1166324386 5.897208e-01 -0.0244967284
3016 P62877 RBX1 0.2218513691 4.439880e-01 -0.0874966282
3017 O15042 U2SURP -0.0161047360 9.276878e-01 -0.0297552513
3018 P49773 HINT1 -0.1379516169 6.318629e-01 -0.0341436443
3019 Q96I59 NARS2 1.0166316559 7.143620e-07 -0.0574236054
3020 P22102 GART 0.7042133520 2.834512e-06 -0.0467881274
3021 P30536 TSPO 0.6316748503 8.172379e-02 -0.0411662269
3022 Q7L1Q6 BZW1 -0.7628026509 3.260348e-04 0.0292095329
3023 Q6YP21 KYAT3 0.2018132983 6.613060e-01 0.0314756211
3024 Q6PI78 TMEM65 0.1878647364 6.636985e-01 0.0195001860
3025 Q13332 PTPRS 0.8745648238 2.123910e-04 0.0545269636
3026 Q8TBP6 SLC25A40 1.9401236779 6.001086e-07 -0.0390977985
3027 Q01105 SET 0.2092224347 4.810934e-02 0.0270707888
3028 P35232 PHB1 0.1900217351 1.817125e-01 0.0224839973
3029 Q9Y6I9 TEX264 -0.7453207723 8.456383e-05 -0.0483702150
3030 P21439 ABCB4 1.0203498263 2.425988e-01 -0.0497880231
3031 Q92973 TNPO1 -0.4401618813 1.315258e-02 0.0198726779
3032 Q9BVV7 TIMM21 -1.1822153430 1.712730e-04 -0.0313154583
3033 O95819 MAP4K4 -0.1144830644 4.857575e-01 0.0156849053
3034 Q9BYF1 ACE2 -0.5906885614 3.816490e-01 0.0793961049
3035 P67870 CSNK2B -0.6984376508 3.070101e-06 0.0288732120
3036 Q9NVD7 PARVA 0.1355749274 5.577359e-01 0.0277182598
3037 P61457 PCBD1 0.4464298248 2.985501e-02 -0.0361964573
3038 Q9BZQ8 NIBAN1 0.9002107348 7.886595e-04 0.0323376874
3039 P35606 COPB2 -0.1909621281 1.036602e-01 -0.0190123058
3040 A3KMH1 VWA8 0.7370869846 5.651123e-05 -0.0221940140
3041 O14874 BCKDK 0.8028773547 2.292041e-04 -0.0170291362
3042 O95299 NDUFA10 -0.1924235477 4.360624e-01 0.0211530589
3043 Q9Y276 BCS1L 0.7675384836 3.652432e-05 0.0253138668
3044 Q14847 LASP1 -0.3395179292 6.075453e-01 -0.0317330085
3045 Q96J01 THOC3 -0.4925124653 2.576464e-02 0.0929392667
3046 P54886 ALDH18A1 1.5203887598 1.204440e-04 -0.0283503541
3047 Q13825 AUH 0.5042923593 3.105908e-02 -0.0180057037
3048 Q9BX67 JAM3 -0.1149739721 7.610126e-01 -0.0213181168
3049 Q9UDW1 UQCR10 0.1886420584 5.456970e-01 0.0192508077
3050 Q8TDJ6 DMXL2 1.3506583196 3.166466e-15 -0.0248687885
3051 Q9Y646 CPQ 0.5196928857 2.021832e-01 -0.0294486905
3052 Q14318 FKBP8 0.2709802649 1.364889e-01 0.0215599964
3053 O15235 MRPS12 0.2728127491 2.836779e-01 0.0235231716
3054 Q9UHN1 POLG2 -0.5267479553 7.661430e-02 -0.0373910423
3055 Q9UI09 NDUFA12 0.5807364513 8.969901e-03 0.0157184413
3056 Q8TBZ3 WDR20 -0.1072198058 6.340491e-01 -0.0671657219
3057 O00746 NME4 1.3230825523 1.076972e-05 0.0320260883
3058 Q15120 PDK3 0.6832118736 2.326997e-01 -0.0235780431
3059 P49754 VPS41 -0.3423971669 6.198518e-03 0.0303422242
3060 O95573 ACSL3 -0.2917174664 7.251713e-02 -0.0221728864
3061 Q8N1G4 LRRC47 -0.2350751143 5.825127e-02 0.0210580657
3062 Q9H9S3 SEC61A2 0.0811316469 6.871579e-01 0.0226494604
3063 P26678 PLN 0.9085794685 8.822501e-02 0.0288374328
3064 Q15392 DHCR24 -0.4128370052 1.646866e-01 -0.0205230860
3065 P13010 XRCC5 0.3662608081 9.610921e-04 -0.0175731941
3066 Q00587 CDC42EP1 -0.8916197699 5.297725e-02 -0.0752537272
3067 Q09666 AHNAK -0.8094230465 1.545179e-02 0.0217256269
3068 Q86SQ0 PHLDB2 1.5240233272 5.490183e-07 -0.0441724106
3069 P50416 CPT1A 0.3146585067 3.191955e-01 -0.0341154233
3070 Q0VGL1 LAMTOR4 -0.2956669260 2.789261e-01 0.0151409905
3071 O75475 PSIP1 -0.6116497229 1.997567e-02 0.0809429909
3072 P01023 A2M -0.7826268095 1.230949e-01 -0.0377802819
3073 Q9ULV4 CORO1C 0.2308388730 6.717477e-01 0.0182228719
3074 P35270 SPR 0.2069392158 3.390036e-01 0.0234553186
3075 P02545 LMNA -1.0291014417 2.898158e-06 0.0158073427
3076 P61421 ATP6V0D1 -0.7736694316 9.987902e-07 -0.0242455672
3077 P20340 RAB6A -0.1669417704 2.294615e-01 0.0176739001
3078 Q9BQA9 CYBC1 -0.8605151337 7.964658e-05 0.0170455743
3079 P25789 PSMA4 0.5185961726 2.026085e-02 -0.0140235078
3080 Q9BXW7 HDHD5 1.2701830353 6.374369e-04 -0.0197262338
3081 Q9UKE5 TNIK 0.4456476235 4.089605e-02 0.0164577249
3082 O94973 AP2A2 0.1869421876 2.482114e-01 -0.0197305999
3083 Q96MW7 TIGD1 0.3470743383 1.691772e-01 -0.0346474874
3084 P57105 SYNJ2BP 0.3761689012 2.160368e-03 0.0161700546
3085 P61009 SPCS3 0.1167641931 7.723840e-01 -0.0137165968
3086 Q9H2H9 SLC38A1 0.0647609380 8.505765e-01 -0.0305677796
3087 Q9H6E4 CCDC134 0.2430253768 1.880425e-01 0.0525545575
3088 Q8NE71 ABCF1 0.0790685762 6.374981e-01 -0.0329983701
3089 Q9NZN4 EHD2 1.6030370855 9.996433e-02 -0.0441618003
3090 Q8TEM1 NUP210 0.5104588892 6.900597e-02 0.0200278664
3091 O43819 SCO2 -0.0471844268 9.026241e-01 -0.0195882447
3092 Q12846 STX4 0.3378154127 1.499675e-02 -0.0173400663
3093 P07355 ANXA2 -0.2026905667 6.951234e-01 0.0282842760
3094 Q6P0N0 MIS18BP1 2.7518481437 1.082586e-10 0.0204778709
3095 Q6P1M3 LLGL2 -0.5150639949 2.034917e-02 0.0223517389
3096 Q13177 PAK2 -0.6036129385 2.943655e-03 0.0251638166
3097 Q9Y4G6 TLN2 0.9349376081 4.886475e-03 0.0148237056
3098 O75907 DGAT1 0.2234994147 1.978209e-01 0.0342642041
3099 P47897 QARS1 0.2938181134 2.984274e-02 -0.0160481348
3100 P63000 RAC1 -0.2137928968 1.858278e-01 0.0191741341
3101 Q96G01 BICD1 -0.3388426676 2.133358e-01 0.0344546541
3102 Q9NTK5 OLA1 0.7241822759 6.861437e-06 0.0268868800
3103 Q86UP2 KTN1 0.1780880035 3.197922e-01 -0.0140971525
3104 O95479 H6PD 0.1099685925 6.512518e-01 -0.0149775013
3105 P30084 ECHS1 0.0168521672 9.291116e-01 0.0136627494
3106 Q9NRV9 HEBP1 -0.5132258586 9.516790e-03 0.0285287161
3107 P62805 H4C8 -2.7245675048 7.519319e-11 0.0194275477
3108 P62805 H4C5 -2.9527234766 2.207268e-07 0.0194275477
3109 P62805 H4C15 -2.2859726782 5.044427e-11 0.0194275477
3110 P62805 H4C14 -2.0606580779 1.773268e-08 0.0194275477
3111 P10301 RRAS 0.1390198776 7.458194e-01 0.0196646958
3112 O43684 BUB3 -0.1754186697 3.296098e-01 -0.0140960751
3113 Q14155 ARHGEF7 -0.1409333665 3.767675e-01 -0.0700116742
3114 Q8TD19 NEK9 -0.2515666216 4.741768e-01 0.0582896964
3115 O14958 CASQ2 0.3476369101 6.032927e-01 -0.0365787285
3116 Q15560 TCEA2 0.5014046138 3.991481e-02 -0.0373465566
3117 Q9Y6N5 SQOR 0.1397066292 8.236833e-01 -0.0502072562
3118 O76003 GLRX3 0.0548451172 8.412810e-01 0.0217527662
3119 Q9BR39 JPH2 1.3996598205 4.118762e-06 -0.0100676478
3120 Q5TAQ9 DCAF8 0.0640316982 7.077788e-01 0.0318414456
3121 Q96E39 RBMXL1 0.3229307715 2.700938e-02 0.0312585100
3122 P61204 ARF3 -0.4700240365 1.589026e-02 -0.0112127960
3123 Q14934 NFATC4 -0.4328217777 3.813405e-02 -0.0184688461
3124 Q15005 SPCS2 0.5138570794 4.040089e-04 0.0124065929
3125 Q9C0D9 SELENOI 0.0956465108 7.108595e-01 0.0296622413
3126 Q9Y320 TMX2 0.5081431072 9.349774e-04 0.0119171151
3127 P11498 PC -0.1279676899 6.192951e-01 0.0339686151
3128 O60763 USO1 0.1767036449 1.186142e-01 -0.0139831853
3129 P33993 MCM7 1.6226689175 8.792193e-07 0.0296264221
3130 Q86VU5 COMTD1 0.3015082903 3.842097e-01 -0.0246204336
3131 P35998 PSMC2 0.0231186175 8.944290e-01 -0.0100998261
3132 O75369 FLNB -0.0988592747 9.144939e-01 -0.0491792455
3133 Q9P2R3 ANKFY1 -0.2411544325 1.167302e-01 -0.0160556032
3134 P20618 PSMB1 0.3643194792 7.400782e-02 0.0094208407
3135 Q5XKP0 MICOS13 0.4489559445 1.169351e-01 0.0182047101
3136 P51809 VAMP7 -0.3296392471 5.366326e-02 0.0184585233
3137 O15228 GNPAT 0.5005834735 3.422489e-03 -0.0163471219
3138 P46939 UTRN 0.4003524332 2.914426e-02 0.0183565192
3139 P09382 LGALS1 0.4366035639 5.617892e-01 -0.0307928569
3140 P27694 RPA1 -0.3150572590 7.233654e-02 0.0277877963
3141 O00462 MANBA 0.2662210358 3.998225e-01 -0.0097998990
3142 P22307 SCP2 0.2471783199 3.591419e-01 -0.0145158437
3143 Q9NZM3 ITSN2 0.3906259040 2.459316e-02 0.0221290468
3144 P34931 HSPA1L -0.1067583432 7.947659e-01 -0.0198052635
3145 P16219 ACADS 0.4397877130 1.742002e-01 -0.0142894513
3146 Q9BS26 ERP44 0.6267901797 1.141002e-05 0.0118885102
3147 Q14974 KPNB1 0.9432231406 7.270882e-10 0.0091638057
3148 Q9UN42 ATP1B4 0.7789519298 5.729877e-01 0.0529851700
3149 P50402 EMD -0.1146204067 5.251555e-01 -0.0092716097
3150 P01112 HRAS -1.3080030120 7.714755e-08 0.0135000733
3151 Q9NUM4 TMEM106B 0.9923341901 2.604878e-05 0.0223334393
3152 Q9BWM7 SFXN3 0.5876231794 2.824172e-01 0.0217927237
3153 Q969M1 TOMM40L 1.2197492234 1.149390e-05 0.0210633620
3154 P05166 PCCB 0.1026136481 4.873153e-01 0.0107373080
3155 Q8N2H3 PYROXD2 0.0147736392 9.855048e-01 0.0407270612
3156 P46060 RANGAP1 -0.0845947963 6.817385e-01 0.0101036945
3157 P24043 LAMA2 0.6610700824 2.990604e-01 -0.0286933388
3158 P13051 UNG 1.1137115328 1.077001e-07 -0.0239032109
3159 Q02252 ALDH6A1 0.1345489239 6.551229e-01 0.0114156845
3160 Q8NFH5 NUP35 1.2799588222 2.700240e-08 -0.0086793530
3161 Q9UBM7 DHCR7 1.0892388385 1.358450e-02 0.0265568097
3162 Q9NVT9 ARMC1 0.0866637493 6.250554e-01 -0.0695866795
3163 Q15691 MAPRE1 -0.6423155724 1.590333e-05 -0.0244255009
3164 Q15070 OXA1L 0.2981550034 1.153250e-01 -0.0250575927
3165 P06865 HEXA -0.0187833157 9.313407e-01 0.0111440839
3166 Q4G176 ACSF3 1.1645840358 1.571268e-02 -0.0116557149
3167 O00425 IGF2BP3 -0.4670322192 8.058652e-04 -0.0088968604
3168 Q02127 DHODH 1.8919553629 5.550083e-12 0.0119945538
3169 Q14677 CLINT1 0.1495156037 2.684732e-01 0.0118688959
3170 P08651 NFIC 1.9127591142 2.248686e-15 -0.0121724593
3171 P28066 PSMA5 -0.2176952181 1.420118e-01 0.0076420581
3172 Q14249 ENDOG 0.3419305487 4.772243e-01 0.0095893912
3173 Q9UDY2 TJP2 -1.1744660791 2.003505e-08 -0.0253243845
3174 Q99755 PIP5K1A 0.0111524942 9.537761e-01 0.0418349618
3175 Q9Y2P4 SLC27A6 0.9096650750 2.543357e-01 0.0127607804
3176 P63165 SUMO1 -0.2733551581 1.024787e-01 0.0123175233
3177 Q9H019 MTFR1L 0.1761738518 6.206019e-01 -0.0092611101
3178 Q8TDY8 IGDCC4 -0.8128632371 2.440708e-03 -0.0426163562
3179 Q9NYF8 BCLAF1 0.2932623368 1.890975e-02 0.0085150296
3180 Q9HD23 MRS2 0.3101874977 4.655500e-02 0.0119060604
3181 P48723 HSPA13 0.1042271604 7.302969e-01 -0.0102901119
3182 Q99594 TEAD3 -0.6127353076 3.124291e-03 -0.0193135842
3183 Q9Y2U8 LEMD3 0.0059412212 9.832385e-01 0.0098060997
3184 O75027 ABCB7 0.9356320038 1.890166e-05 -0.0099842542
3185 Q5SSJ5 HP1BP3 0.0675528760 7.509103e-01 0.0073752285
3186 O75400 PRPF40A -0.0549315875 7.319072e-01 -0.0124379818
3187 P31327 CPS1 1.5260089265 6.817051e-04 0.0136571174
3188 Q9Y2A7 NCKAP1 0.3523055106 3.956756e-02 0.0125353448
3189 Q9UID3 VPS51 0.0771549269 6.996361e-01 0.0295843740
3190 P14543 NID1 -0.2633962284 4.247204e-01 -0.0167919221
3191 P17152 TMEM11 0.0286310894 8.567453e-01 -0.0105953273
3192 Q13620 CUL4B -0.4921538337 7.337643e-02 0.0145089750
3193 P29992 GNA11 -0.6461457364 3.650651e-07 -0.0064416056
3194 Q5T2T1 MPP7 -0.2481676820 4.607929e-01 0.0097889222
3195 P62140 PPP1CB 0.2134131014 4.178096e-01 0.0079203715
3196 Q969V3 NCLN -0.0609534742 8.747069e-01 -0.0091642882
3197 O75063 FAM20B 0.1715353466 2.151519e-01 -0.0196776515
3198 O43765 SGTA 0.2010962403 8.891681e-02 -0.0198025217
3199 Q8N2F6 ARMC10 -0.4916332128 9.634105e-04 -0.0198511112
3200 Q8WVX9 FAR1 0.6817842559 4.435381e-05 0.0060289228
3201 Q14139 UBE4A 0.0979763946 4.584974e-01 -0.0057615311
3202 P82933 MRPS9 0.5729337775 5.871366e-05 0.0054829992
3203 Q01813 PFKP 0.0705533351 8.759288e-01 0.0167370873
3204 Q9BX66 SORBS1 -0.4013435088 7.140031e-02 0.0143358680
3205 P60891 PRPS1 0.5359664952 7.300156e-02 0.0067843410
3206 P11021 HSPA5 0.2682169864 4.379946e-01 0.0063562359
3207 Q9NSV4 DIAPH3 0.7020462709 2.493912e-01 0.0171790228
3208 P02786 TFRC 1.5455329480 3.304262e-04 0.0070610326
3209 Q15075 EEA1 0.0829040645 6.871269e-01 0.0050036274
3210 P50440 GATM 0.7038263127 1.382235e-01 0.0143064229
3211 Q96ER9 CCDC51 -0.5241830027 7.299311e-03 -0.0102512056
3212 Q9H0V9 LMAN2L 0.6921431823 2.649489e-06 -0.0093153054
3213 Q96SJ8 TSPAN18 0.0674229287 8.815904e-01 -0.0156754084
3214 Q9UDR5 AASS 0.9031965755 2.943655e-03 0.0064776062
3215 Q99436 PSMB7 -0.1022043027 3.871833e-01 0.0067940073
3216 P07910 HNRNPC -0.5452201778 5.358031e-05 0.0061472861
3217 P43121 MCAM 2.0332566656 1.122956e-09 0.0072381493
3218 Q969Z3 MTARC2 0.9380548958 7.362719e-04 -0.0054001601
3219 Q9P291 ARMCX1 0.6436026123 2.930719e-03 0.0057158178
3220 Q96I51 RCC1L -0.3310989706 1.371312e-02 -0.0099153320
3221 P12270 TPR 0.4146819754 1.936013e-03 -0.0063074599
3222 P62993 GRB2 -0.0768717211 4.312790e-01 -0.0191703184
3223 O43852 CALU 0.3836205232 1.936299e-01 -0.0066212747
3224 O00186 STXBP3 -0.4161157469 1.248110e-02 -0.0047971737
3225 P61020 RAB5B -0.0792640258 5.992235e-01 0.0097273667
3226 Q9UJW0 DCTN4 0.1585282383 1.226075e-01 -0.0059093156
3227 P50213 IDH3A 0.9143527199 6.021090e-04 -0.0051954398
3228 P13861 PRKAR2A 0.1909003014 3.003278e-01 -0.0050914180
3229 Q8NDZ4 DIPK2A 0.2985381973 3.603724e-01 -0.0086632938
3230 P35659 DEK 0.6836197263 1.763743e-02 -0.0044616574
3231 P56747 CLDN6 0.4903047750 1.301154e-01 0.0187623726
3232 O95861 BPNT1 0.8153466543 1.751936e-05 -0.0054869445
3233 Q68D91 MBLAC2 -0.1752900634 4.472219e-01 -0.0095284586
3234 Q96D53 COQ8B -0.1903233352 4.352588e-01 -0.0072857034
3235 Q9GZP0 PDGFD 0.9065061387 3.524099e-02 0.0175080541
3236 Q9UBX3 SLC25A10 1.5233884781 2.215949e-10 -0.0059197351
3237 Q6Y288 B3GLCT -0.9350382810 1.592378e-03 0.0073062541
3238 Q58EX2 SDK2 1.2372282600 1.963646e-05 0.0102423104
3239 Q9P035 HACD3 0.4664993474 7.779180e-02 -0.0044522294
3240 Q92614 MYO18A 0.7032231392 5.900807e-03 -0.0028647118
3241 O75376 NCOR1 -0.6248074879 1.936455e-03 0.0074416599
3242 O43615 TIMM44 0.6372452977 2.088844e-03 0.0037622817
3243 O43169 CYB5B 0.0207338294 9.023055e-01 0.0032027964
3244 Q6UW68 TMEM205 0.7648176669 2.305697e-05 0.0046572920
3245 P35968 KDR 0.5396634797 3.298585e-01 0.0047097694
3246 Q9GZY4 COA1 0.4899337125 1.306507e-01 -0.0055021156
3247 Q8IZQ5 SELENOH 0.0080352488 9.809982e-01 0.0066248105
3248 O60841 EIF5B 0.0939207590 6.100031e-01 -0.0035220559
3249 P28288 ABCD3 0.3486283733 1.780447e-02 -0.0036256509
3250 O75417 POLQ 2.0084178247 2.456687e-08 0.0054159815
3251 Q15067 ACOX1 -0.1888053822 2.916021e-01 0.0044210791
3252 P26368 U2AF2 -0.2995128873 4.417443e-03 -0.0022281622
3253 P23919 DTYMK 1.0407036283 3.597197e-05 -0.0032968988
3254 Q155Q3 DIXDC1 -0.0216990060 9.530237e-01 0.0028108220
3255 Q13232 NME3 2.2205860983 6.412236e-09 -0.0035464856
3256 Q6FI81 CIAPIN1 0.2869803544 8.507572e-03 0.0039575492
3257 O00505 KPNA3 0.4226836097 1.074772e-03 0.0085658006
3258 Q15008 PSMD6 -0.1794564923 1.605670e-01 0.0024531736
3259 O00743 PPP6C -0.3952961380 8.692695e-06 -0.0030229107
3260 Q32P44 EML3 0.1031835408 8.208870e-01 -0.0035448747
3261 P78417 GSTO1 -0.7720264821 6.570597e-03 0.0018041193
3262 P14621 ACYP2 -2.3099234235 8.318853e-09 -0.0045005530
3263 Q9BYD1 MRPL13 -0.0843465279 7.318300e-01 0.0015316464
3264 P61586 RHOA -0.0975989751 5.854557e-01 0.0013072005
3265 Q14566 MCM6 2.5297553942 3.031080e-10 0.0021581420
3266 P10915 HAPLN1 0.7550889191 5.260410e-01 0.0050398203
3267 Q9BXS5 AP1M1 0.0372683532 8.288891e-01 -0.0015175385
3268 Q6P1M0 SLC27A4 0.2759765041 2.808763e-01 -0.0013230822
3269 Q9C0D5 TANC1 0.3162078526 1.096049e-01 0.0037181052
3270 Q15185 PTGES3 0.0428233703 8.302442e-01 0.0008048923
3271 P51153 RAB13 0.3747905233 1.379279e-02 0.0012681861
3272 P29144 TPP2 -0.6679554631 7.847579e-05 0.0012070742
3273 P09543 CNP 1.0420442423 1.296586e-05 0.0006074187
3274 Q9BZF1 OSBPL8 -0.6917398010 7.666300e-04 -0.0006529423
3275 Q92538 GBF1 0.3110954419 8.157964e-02 0.0002573516
3276 Q96N64 PWWP2A 0.0988589150 4.579309e-01 -0.0002124377
3277 Q52LJ0 FAM98B 0.2406146738 5.528765e-02 -0.0003543919
3278 P54753 EPHB3 0.6993813551 7.733194e-02 -0.0002160733
Pro_Pval sign_match delta_logFC Upper_quant
1 6.951913e-05 FALSE 4.0961864246 TRUE
2 2.443330e-04 TRUE 1.8245604847 FALSE
3 3.034614e-04 TRUE 1.2580368818 FALSE
4 3.918893e-04 TRUE 3.6542200096 TRUE
5 3.940743e-04 FALSE 1.3492501561 FALSE
6 8.142856e-04 FALSE 2.1115671749 TRUE
7 1.278129e-03 FALSE 3.3858026389 TRUE
8 1.572259e-03 TRUE 0.4017811005 FALSE
9 1.881965e-03 FALSE 3.0204363862 TRUE
10 1.881965e-03 FALSE 1.0569056170 FALSE
11 1.881965e-03 TRUE 0.5956266202 FALSE
12 1.881965e-03 FALSE 2.8271043027 TRUE
13 2.500644e-03 FALSE 1.0720761781 FALSE
14 2.711717e-03 FALSE 2.5718561759 TRUE
15 2.711717e-03 FALSE 1.8116489603 FALSE
16 2.717316e-03 FALSE 1.7788574655 FALSE
17 3.007123e-03 FALSE 1.0623471286 FALSE
18 3.007123e-03 FALSE 0.9322249767 FALSE
19 3.156765e-03 FALSE 2.5965406701 TRUE
20 3.156765e-03 FALSE 1.0786949217 FALSE
21 3.156765e-03 TRUE 1.0693304218 FALSE
22 3.912381e-03 FALSE 2.1865598321 TRUE
23 4.145419e-03 FALSE 1.4339970353 FALSE
24 4.358840e-03 FALSE 1.3506158167 FALSE
25 4.534280e-03 TRUE 0.4847919072 FALSE
26 4.654352e-03 FALSE 1.1456024818 FALSE
27 5.057106e-03 TRUE 1.1043775767 FALSE
28 5.057106e-03 FALSE 2.7925565575 TRUE
29 5.057106e-03 FALSE 2.9808919211 TRUE
30 5.057106e-03 FALSE 2.0825481592 TRUE
31 5.057106e-03 FALSE 1.6596221669 FALSE
32 5.472898e-03 FALSE 4.0238075319 TRUE
33 5.521477e-03 FALSE 1.8705818769 TRUE
34 5.521477e-03 TRUE 0.5830719704 FALSE
35 5.610083e-03 FALSE 4.4937132950 TRUE
36 5.610083e-03 FALSE 2.2164881676 TRUE
37 5.610083e-03 FALSE 2.0319061085 TRUE
38 6.595355e-03 FALSE 1.1499372980 FALSE
39 6.971593e-03 TRUE 0.6125415096 FALSE
40 7.360475e-03 FALSE 0.7944301004 FALSE
41 7.537546e-03 FALSE 0.7488775917 FALSE
42 7.845298e-03 TRUE 0.2881598776 FALSE
43 7.847079e-03 FALSE 1.4283475860 FALSE
44 7.847079e-03 FALSE 0.9943021551 FALSE
45 7.847079e-03 TRUE 0.5036262448 FALSE
46 8.197740e-03 FALSE 1.8966704320 TRUE
47 8.454480e-03 FALSE 1.2681497485 FALSE
48 8.635514e-03 TRUE 0.6386222300 FALSE
49 9.414723e-03 FALSE 2.0408582802 TRUE
50 1.022209e-02 TRUE 1.1039491437 FALSE
51 1.029373e-02 FALSE 1.0563313463 FALSE
52 1.029373e-02 TRUE 0.3792885928 FALSE
53 1.029373e-02 FALSE 1.2838035761 FALSE
54 1.029373e-02 FALSE 0.9504383179 FALSE
55 1.086007e-02 TRUE 1.6779040891 FALSE
56 1.086007e-02 TRUE 0.4696977730 FALSE
57 1.086007e-02 TRUE 0.5771483474 FALSE
58 1.116432e-02 FALSE 1.6367045733 FALSE
59 1.116432e-02 FALSE 0.9585857204 FALSE
60 1.116432e-02 FALSE 2.7709596064 TRUE
61 1.177343e-02 TRUE 1.7262253230 FALSE
62 1.233495e-02 FALSE 0.9300022891 FALSE
63 1.325802e-02 TRUE 0.4289246355 FALSE
64 1.325802e-02 TRUE 0.4146200045 FALSE
65 1.325802e-02 TRUE 0.4022706827 FALSE
66 1.325802e-02 FALSE 2.2560273217 TRUE
67 1.326771e-02 FALSE 0.6569515831 FALSE
68 1.326771e-02 FALSE 1.9277510943 TRUE
69 1.326771e-02 TRUE 0.6514508255 FALSE
70 1.326771e-02 TRUE 0.5465574799 FALSE
71 1.326771e-02 FALSE 1.1617534182 FALSE
72 1.333621e-02 TRUE 0.5170318875 FALSE
73 1.333621e-02 TRUE 0.2338491604 FALSE
74 1.333621e-02 FALSE 2.4411232407 TRUE
75 1.333621e-02 FALSE 0.8935294347 FALSE
76 1.333621e-02 FALSE 1.1820592459 FALSE
77 1.333621e-02 TRUE 0.6048774818 FALSE
78 1.333621e-02 FALSE 0.9381489554 FALSE
79 1.333621e-02 TRUE 0.8463901301 FALSE
80 1.349230e-02 TRUE 0.5622511342 FALSE
81 1.354980e-02 TRUE 0.4390906565 FALSE
82 1.424497e-02 TRUE 0.3394132474 FALSE
83 1.424497e-02 FALSE 0.7029390562 FALSE
84 1.429047e-02 TRUE 0.6004303130 FALSE
85 1.448893e-02 TRUE 0.2675113048 FALSE
86 1.448893e-02 FALSE 2.3755343466 TRUE
87 1.490927e-02 TRUE 0.8385777451 FALSE
88 1.511453e-02 TRUE 1.1065956371 FALSE
89 1.511453e-02 TRUE 0.8019510352 FALSE
90 1.511919e-02 TRUE 0.2027651810 FALSE
91 1.522705e-02 FALSE 1.1219898194 FALSE
92 1.540433e-02 TRUE 0.1618911967 FALSE
93 1.540433e-02 TRUE 0.3217711153 FALSE
94 1.544898e-02 TRUE 0.3992141351 FALSE
95 1.560784e-02 TRUE 0.1357322547 FALSE
96 1.592196e-02 FALSE 2.2255342515 TRUE
97 1.602160e-02 FALSE 0.9061403976 FALSE
98 1.629803e-02 TRUE 0.2398283522 FALSE
99 1.712715e-02 TRUE 0.2622166002 FALSE
100 1.754874e-02 TRUE 1.1514391487 FALSE
101 1.754874e-02 FALSE 0.7438978431 FALSE
102 1.754874e-02 FALSE 2.0312703968 TRUE
103 1.844926e-02 FALSE 0.9028499346 FALSE
104 1.847809e-02 FALSE 0.7212781213 FALSE
105 1.924691e-02 FALSE 0.6033864304 FALSE
106 1.980493e-02 TRUE 0.4225422839 FALSE
107 1.980493e-02 FALSE 1.1918443100 FALSE
108 1.999753e-02 FALSE 0.5743554200 FALSE
109 2.001937e-02 FALSE 0.9509630346 FALSE
110 2.030277e-02 TRUE 0.2081079330 FALSE
111 2.030277e-02 FALSE 1.6478580408 FALSE
112 2.030277e-02 FALSE 2.5963626496 TRUE
113 2.030277e-02 FALSE 0.8249133018 FALSE
114 2.030277e-02 FALSE 2.1140912065 TRUE
115 2.030277e-02 TRUE 1.0303577486 FALSE
116 2.030277e-02 TRUE 0.1381957548 FALSE
117 2.030277e-02 FALSE 2.4348953372 TRUE
118 2.030277e-02 FALSE 1.9898255541 TRUE
119 2.043186e-02 FALSE 1.2347437286 FALSE
120 2.062576e-02 FALSE 1.4514329576 FALSE
121 2.062576e-02 TRUE 0.2573932047 FALSE
122 2.117750e-02 TRUE 0.6145765517 FALSE
123 2.117750e-02 FALSE 1.1153085877 FALSE
124 2.117750e-02 TRUE 2.2551695346 TRUE
125 2.117750e-02 TRUE 0.6237777413 FALSE
126 2.153822e-02 FALSE 0.6590585110 FALSE
127 2.200363e-02 FALSE 1.0266017297 FALSE
128 2.245624e-02 TRUE 0.3509413277 FALSE
129 2.254563e-02 FALSE 1.7943590040 FALSE
130 2.254563e-02 TRUE 0.1794368408 FALSE
131 2.266300e-02 TRUE 0.1436771859 FALSE
132 2.302224e-02 TRUE 1.1256283650 FALSE
133 2.302224e-02 TRUE 0.1785686990 FALSE
134 2.304203e-02 FALSE 0.5313770133 FALSE
135 2.307093e-02 FALSE 0.6118603269 FALSE
136 2.307093e-02 FALSE 0.7045547385 FALSE
137 2.307093e-02 FALSE 1.2318804961 FALSE
138 2.307093e-02 FALSE 0.7351212622 FALSE
139 2.320441e-02 FALSE 0.9966578808 FALSE
140 2.320441e-02 TRUE 0.1797829579 FALSE
141 2.320441e-02 FALSE 2.4116868315 TRUE
142 2.320441e-02 TRUE 1.3993020743 FALSE
143 2.334638e-02 TRUE 0.0589645654 FALSE
144 2.352702e-02 FALSE 2.5225175350 TRUE
145 2.435103e-02 FALSE 0.6258914705 FALSE
146 2.436489e-02 FALSE 1.9398481990 TRUE
147 2.470591e-02 FALSE 8.2496045250 TRUE
148 2.542329e-02 TRUE 0.8922202907 FALSE
149 2.542329e-02 TRUE 0.0661851593 FALSE
150 2.543895e-02 FALSE 1.0013223674 FALSE
151 2.627630e-02 TRUE 0.2872363091 FALSE
152 2.627630e-02 TRUE 1.0968810670 FALSE
153 2.627630e-02 FALSE 1.7703390177 FALSE
154 2.627630e-02 FALSE 4.3386891070 TRUE
155 2.693134e-02 FALSE 0.6517052830 FALSE
156 2.700475e-02 FALSE 1.4452637773 FALSE
157 2.701559e-02 FALSE 1.7047915324 FALSE
158 2.837538e-02 TRUE 0.0510496299 FALSE
159 2.837538e-02 FALSE 1.7570147195 FALSE
160 2.843616e-02 FALSE 1.6535316380 FALSE
161 2.977678e-02 TRUE 0.1038534142 FALSE
162 2.989137e-02 FALSE 1.5881436086 FALSE
163 2.989137e-02 TRUE 0.3699534966 FALSE
164 3.000713e-02 FALSE 1.4871880284 FALSE
165 3.000713e-02 FALSE 2.9276321716 TRUE
166 3.035656e-02 FALSE 0.8554297998 FALSE
167 3.035656e-02 FALSE 1.2197640167 FALSE
168 3.035656e-02 FALSE 2.3098150655 TRUE
169 3.035656e-02 FALSE 4.8542763314 TRUE
170 3.042248e-02 FALSE 2.4982115216 TRUE
171 3.042248e-02 FALSE 1.3918582030 FALSE
172 3.042248e-02 FALSE 0.6634011466 FALSE
173 3.202089e-02 FALSE 2.4016436238 TRUE
174 3.202089e-02 TRUE 0.8285943367 FALSE
175 3.202089e-02 FALSE 1.3920527761 FALSE
176 3.202089e-02 FALSE 0.7728235367 FALSE
177 3.233857e-02 TRUE 0.9763530075 FALSE
178 3.239557e-02 TRUE 0.0388296915 FALSE
179 3.247939e-02 FALSE 0.9374410006 FALSE
180 3.342171e-02 FALSE 1.3674012805 FALSE
181 3.342171e-02 FALSE 0.7682160954 FALSE
182 3.342171e-02 FALSE 1.5672016432 FALSE
183 3.342171e-02 TRUE 0.7372646708 FALSE
184 3.342171e-02 FALSE 1.6760118176 FALSE
185 3.342171e-02 FALSE 0.6389544313 FALSE
186 3.342171e-02 FALSE 1.3599960709 FALSE
187 3.342171e-02 TRUE 0.6507742954 FALSE
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1900 5.673264e-01 TRUE 0.6943895023 FALSE
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1909 5.675903e-01 FALSE 0.3645943642 FALSE
1910 5.675903e-01 TRUE 0.2924651789 FALSE
1911 5.675903e-01 TRUE 0.2231446650 FALSE
1912 5.684372e-01 TRUE 0.2821327450 FALSE
1913 5.684372e-01 FALSE 0.2906401377 FALSE
1914 5.689242e-01 FALSE 1.8068338361 FALSE
1915 5.689242e-01 FALSE 0.4302737214 FALSE
1916 5.694268e-01 TRUE 0.3079213375 FALSE
1917 5.702876e-01 TRUE 0.2045939152 FALSE
1918 5.710872e-01 FALSE 0.6028993308 FALSE
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1920 5.710872e-01 FALSE 0.9806752829 FALSE
1921 5.710872e-01 TRUE 0.6465710210 FALSE
1922 5.712245e-01 FALSE 0.2490450462 FALSE
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1926 5.712330e-01 TRUE 0.0460088046 FALSE
1927 5.712330e-01 TRUE 0.0200811232 FALSE
1928 5.712330e-01 TRUE 0.2574335916 FALSE
1929 5.712330e-01 FALSE 1.3394764515 FALSE
1930 5.712330e-01 TRUE 0.3596022844 FALSE
1931 5.712330e-01 TRUE 0.1360319849 FALSE
1932 5.712330e-01 TRUE 0.0631615071 FALSE
1933 5.714770e-01 FALSE 0.2348559328 FALSE
1934 5.718801e-01 TRUE 0.2310383371 FALSE
1935 5.718801e-01 TRUE 1.9881419960 TRUE
1936 5.718801e-01 TRUE 0.2842764664 FALSE
1937 5.718801e-01 FALSE 1.0246518906 FALSE
1938 5.718801e-01 FALSE 0.3683755809 FALSE
1939 5.718801e-01 FALSE 0.9978271828 FALSE
1940 5.719697e-01 TRUE 0.2108568091 FALSE
1941 5.719697e-01 TRUE 0.8463743632 FALSE
1942 5.719697e-01 FALSE 0.6219411267 FALSE
1943 5.719697e-01 FALSE 0.1645802952 FALSE
1944 5.735147e-01 TRUE 0.4270642117 FALSE
1945 5.735147e-01 TRUE 0.1144005331 FALSE
1946 5.747606e-01 FALSE 0.2305187521 FALSE
1947 5.763274e-01 FALSE 1.4193567490 FALSE
1948 5.764383e-01 FALSE 1.3811604095 FALSE
1949 5.773523e-01 TRUE 0.1374358896 FALSE
1950 5.773523e-01 FALSE 0.5506244854 FALSE
1951 5.773523e-01 FALSE 0.1536404179 FALSE
1952 5.773523e-01 TRUE 0.2776089996 FALSE
1953 5.787569e-01 FALSE 0.2795711342 FALSE
1954 5.795229e-01 TRUE 0.5090876789 FALSE
1955 5.809205e-01 FALSE 0.1360420905 FALSE
1956 5.812177e-01 FALSE 0.2774982542 FALSE
1957 5.813925e-01 TRUE 0.0678512420 FALSE
1958 5.813925e-01 TRUE 0.4580536540 FALSE
1959 5.815482e-01 FALSE 0.8101521000 FALSE
1960 5.818973e-01 FALSE 0.1904407039 FALSE
1961 5.818973e-01 FALSE 1.5960478957 FALSE
1962 5.818973e-01 TRUE 0.0832611825 FALSE
1963 5.835379e-01 TRUE 0.0064784432 FALSE
1964 5.838129e-01 TRUE 0.0679374414 FALSE
1965 5.863497e-01 TRUE 1.4766782916 FALSE
1966 5.883124e-01 TRUE 0.1523323531 FALSE
1967 5.888986e-01 TRUE 0.2471974515 FALSE
1968 5.891983e-01 TRUE 0.4273256425 FALSE
1969 5.892028e-01 FALSE 0.9965212220 FALSE
1970 5.894094e-01 TRUE 1.1729823564 FALSE
1971 5.897020e-01 TRUE 0.5266558157 FALSE
1972 5.897020e-01 TRUE 0.1663188634 FALSE
1973 5.897982e-01 TRUE 0.3573235729 FALSE
1974 5.897982e-01 FALSE 0.3087994876 FALSE
1975 5.908133e-01 FALSE 0.4230364616 FALSE
1976 5.912307e-01 FALSE 1.6346349916 FALSE
1977 5.914293e-01 FALSE 0.6653394833 FALSE
1978 5.914293e-01 TRUE 0.9066320567 FALSE
1979 5.914293e-01 TRUE 0.7348820381 FALSE
1980 5.933894e-01 TRUE 0.4838656745 FALSE
1981 5.935323e-01 FALSE 0.8550985833 FALSE
1982 5.936906e-01 TRUE 0.4356792180 FALSE
1983 5.940249e-01 FALSE 0.5716954271 FALSE
1984 5.940249e-01 TRUE 0.0717965844 FALSE
1985 5.940717e-01 FALSE 1.3049073482 FALSE
1986 5.943942e-01 TRUE 0.0628017409 FALSE
1987 5.961792e-01 TRUE 0.0477508513 FALSE
1988 5.963798e-01 TRUE 0.2204097844 FALSE
1989 5.963798e-01 TRUE 1.5266574167 FALSE
1990 5.963798e-01 FALSE 0.2030270823 FALSE
1991 5.975355e-01 TRUE 0.0439933713 FALSE
1992 5.982233e-01 TRUE 0.1699492548 FALSE
1993 5.982233e-01 FALSE 0.3838737236 FALSE
1994 5.983942e-01 FALSE 2.5762019882 TRUE
1995 5.983942e-01 FALSE 0.9604296749 FALSE
1996 5.986018e-01 FALSE 0.7541305100 FALSE
1997 5.986018e-01 TRUE 0.0692050538 FALSE
1998 5.986018e-01 FALSE 0.3780686017 FALSE
1999 5.997232e-01 FALSE 0.3174192330 FALSE
2000 5.997232e-01 TRUE 0.1231529782 FALSE
2001 5.997232e-01 TRUE 0.1508992661 FALSE
2002 6.010098e-01 FALSE 1.2611720377 FALSE
2003 6.029413e-01 TRUE 0.2351870195 FALSE
2004 6.032727e-01 FALSE 0.2923716733 FALSE
2005 6.033354e-01 FALSE 0.6605127791 FALSE
2006 6.033354e-01 TRUE 0.1652059401 FALSE
2007 6.033354e-01 FALSE 1.0683899416 FALSE
2008 6.033354e-01 TRUE 0.8063425643 FALSE
2009 6.038950e-01 FALSE 0.2486655898 FALSE
2010 6.038950e-01 TRUE 0.2311438715 FALSE
2011 6.038950e-01 FALSE 0.7839049182 FALSE
2012 6.042933e-01 FALSE 0.2522323291 FALSE
2013 6.043505e-01 FALSE 0.5123281772 FALSE
2014 6.045983e-01 FALSE 0.7116042644 FALSE
2015 6.047004e-01 TRUE 0.0327845820 FALSE
2016 6.049673e-01 TRUE 1.5794290043 FALSE
2017 6.049673e-01 FALSE 0.4347481095 FALSE
2018 6.049673e-01 TRUE 0.2484052721 FALSE
2019 6.049673e-01 TRUE 0.6499834422 FALSE
2020 6.056234e-01 FALSE 0.8063661561 FALSE
2021 6.056234e-01 FALSE 0.6183100604 FALSE
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3094 9.467461e-01 TRUE 2.7313702728 TRUE
3095 9.468161e-01 FALSE 0.5374157338 FALSE
3096 9.490693e-01 FALSE 0.6287767551 FALSE
3097 9.493948e-01 TRUE 0.9201139025 FALSE
3098 9.506632e-01 TRUE 0.1892352105 FALSE
3099 9.508487e-01 FALSE 0.3098662482 FALSE
3100 9.509313e-01 FALSE 0.2329670308 FALSE
3101 9.509619e-01 FALSE 0.3732973217 FALSE
3102 9.509619e-01 TRUE 0.6972953959 FALSE
3103 9.509619e-01 FALSE 0.1921851559 FALSE
3104 9.511539e-01 FALSE 0.1249460938 FALSE
3105 9.524523e-01 TRUE 0.0031894178 FALSE
3106 9.530465e-01 FALSE 0.5417545747 FALSE
3107 9.532769e-01 FALSE 2.7439950525 TRUE
3108 9.532769e-01 FALSE 2.9721510243 TRUE
3109 9.532769e-01 FALSE 2.3054002259 TRUE
3110 9.532769e-01 FALSE 2.0800856256 TRUE
3111 9.532769e-01 TRUE 0.1193551818 FALSE
3112 9.532769e-01 TRUE 0.1613225945 FALSE
3113 9.542532e-01 TRUE 0.0709216923 FALSE
3114 9.573678e-01 FALSE 0.3098563180 FALSE
3115 9.573678e-01 FALSE 0.3842156385 FALSE
3116 9.573678e-01 FALSE 0.5387511704 FALSE
3117 9.573678e-01 FALSE 0.1899138854 FALSE
3118 9.576748e-01 TRUE 0.0330923510 FALSE
3119 9.578815e-01 FALSE 1.4097274683 FALSE
3120 9.585062e-01 TRUE 0.0321902526 FALSE
3121 9.585062e-01 TRUE 0.2916722615 FALSE
3122 9.588010e-01 TRUE 0.4588112406 FALSE
3123 9.590088e-01 TRUE 0.4143529317 FALSE
3124 9.592422e-01 TRUE 0.5014504864 FALSE
3125 9.592422e-01 TRUE 0.0659842695 FALSE
3126 9.601543e-01 TRUE 0.4962259921 FALSE
3127 9.603356e-01 FALSE 0.1619363050 FALSE
3128 9.603356e-01 FALSE 0.1906868302 FALSE
3129 9.603356e-01 TRUE 1.5930424955 FALSE
3130 9.603356e-01 FALSE 0.3261287239 FALSE
3131 9.603356e-01 FALSE 0.0332184436 FALSE
3132 9.603356e-01 TRUE 0.0496800292 FALSE
3133 9.603356e-01 TRUE 0.2250988293 FALSE
3134 9.603700e-01 TRUE 0.3548986385 FALSE
3135 9.611400e-01 TRUE 0.4307512343 FALSE
3136 9.620671e-01 FALSE 0.3480977704 FALSE
3137 9.623151e-01 FALSE 0.5169305955 FALSE
3138 9.627406e-01 TRUE 0.3819959141 FALSE
3139 9.633472e-01 FALSE 0.4673964209 FALSE
3140 9.633472e-01 FALSE 0.3428450553 FALSE
3141 9.633472e-01 FALSE 0.2760209348 FALSE
3142 9.633472e-01 FALSE 0.2616941636 FALSE
3143 9.636073e-01 TRUE 0.3684968572 FALSE
3144 9.636073e-01 TRUE 0.0869530796 FALSE
3145 9.636073e-01 FALSE 0.4540771643 FALSE
3146 9.636073e-01 TRUE 0.6149016696 FALSE
3147 9.636073e-01 TRUE 0.9340593349 FALSE
3148 9.636073e-01 TRUE 0.7259667598 FALSE
3149 9.636073e-01 TRUE 0.1053487970 FALSE
3150 9.636073e-01 FALSE 1.3215030852 FALSE
3151 9.636750e-01 TRUE 0.9700007508 FALSE
3152 9.636750e-01 TRUE 0.5658304557 FALSE
3153 9.636750e-01 TRUE 1.1986858614 FALSE
3154 9.639401e-01 TRUE 0.0918763402 FALSE
3155 9.642394e-01 TRUE 0.0259534220 FALSE
3156 9.642394e-01 FALSE 0.0946984908 FALSE
3157 9.642394e-01 FALSE 0.6897634212 FALSE
3158 9.642394e-01 FALSE 1.1376147436 FALSE
3159 9.642394e-01 TRUE 0.1231332393 FALSE
3160 9.642394e-01 FALSE 1.2886381752 FALSE
3161 9.642394e-01 TRUE 1.0626820288 FALSE
3162 9.642394e-01 FALSE 0.1562504288 FALSE
3163 9.642394e-01 TRUE 0.6178900715 FALSE
3164 9.654389e-01 FALSE 0.3232125960 FALSE
3165 9.654389e-01 FALSE 0.0299273996 FALSE
3166 9.667488e-01 FALSE 1.1762397507 FALSE
3167 9.667488e-01 TRUE 0.4581353588 FALSE
3168 9.667488e-01 TRUE 1.8799608091 TRUE
3169 9.667488e-01 TRUE 0.1376467078 FALSE
3170 9.667488e-01 FALSE 1.9249315735 TRUE
3171 9.667488e-01 FALSE 0.2253372762 FALSE
3172 9.667488e-01 TRUE 0.3323411576 FALSE
3173 9.667488e-01 TRUE 1.1491416946 FALSE
3174 9.667488e-01 TRUE 0.0306824676 FALSE
3175 9.673031e-01 TRUE 0.8969042946 FALSE
3176 9.678086e-01 FALSE 0.2856726814 FALSE
3177 9.678086e-01 FALSE 0.1854349619 FALSE
3178 9.679082e-01 TRUE 0.7702468809 FALSE
3179 9.679082e-01 TRUE 0.2847473072 FALSE
3180 9.679082e-01 TRUE 0.2982814373 FALSE
3181 9.680796e-01 FALSE 0.1145172723 FALSE
3182 9.682065e-01 TRUE 0.5934217234 FALSE
3183 9.682065e-01 TRUE 0.0038648785 FALSE
3184 9.691118e-01 FALSE 0.9456162580 FALSE
3185 9.691118e-01 TRUE 0.0601776474 FALSE
3186 9.691118e-01 TRUE 0.0424936057 FALSE
3187 9.691118e-01 TRUE 1.5123518091 FALSE
3188 9.691118e-01 TRUE 0.3397701659 FALSE
3189 9.691118e-01 TRUE 0.0475705529 FALSE
3190 9.691118e-01 TRUE 0.2466043063 FALSE
3191 9.691118e-01 FALSE 0.0392264167 FALSE
3192 9.710227e-01 FALSE 0.5066628087 FALSE
3193 9.710227e-01 TRUE 0.6397041308 FALSE
3194 9.714922e-01 FALSE 0.2579566043 FALSE
3195 9.721262e-01 TRUE 0.2054927299 FALSE
3196 9.721262e-01 TRUE 0.0517891860 FALSE
3197 9.721262e-01 FALSE 0.1912129981 FALSE
3198 9.721262e-01 FALSE 0.2208987620 FALSE
3199 9.735650e-01 TRUE 0.4717821017 FALSE
3200 9.759324e-01 TRUE 0.6757553331 FALSE
3201 9.772588e-01 FALSE 0.1037379257 FALSE
3202 9.781625e-01 TRUE 0.5674507783 FALSE
3203 9.781625e-01 TRUE 0.0538162479 FALSE
3204 9.783663e-01 FALSE 0.4156793767 FALSE
3205 9.783663e-01 TRUE 0.5291821543 FALSE
3206 9.783663e-01 TRUE 0.2618607505 FALSE
3207 9.783663e-01 TRUE 0.6848672481 FALSE
3208 9.788418e-01 TRUE 1.5384719154 FALSE
3209 9.790569e-01 TRUE 0.0779004371 FALSE
3210 9.791069e-01 TRUE 0.6895198897 FALSE
3211 9.791635e-01 TRUE 0.5139317970 FALSE
3212 9.793194e-01 FALSE 0.7014584876 FALSE
3213 9.800853e-01 FALSE 0.0830983370 FALSE
3214 9.812624e-01 TRUE 0.8967189692 FALSE
3215 9.812624e-01 FALSE 0.1089983100 FALSE
3216 9.812624e-01 FALSE 0.5513674640 FALSE
3217 9.812624e-01 TRUE 2.0260185163 TRUE
3218 9.812624e-01 FALSE 0.9434550559 FALSE
3219 9.812624e-01 TRUE 0.6378867946 FALSE
3220 9.813716e-01 TRUE 0.3211836386 FALSE
3221 9.814281e-01 FALSE 0.4209894352 FALSE
3222 9.814281e-01 TRUE 0.0577014027 FALSE
3223 9.814281e-01 FALSE 0.3902417979 FALSE
3224 9.833495e-01 TRUE 0.4113185731 FALSE
3225 9.835213e-01 FALSE 0.0889913924 FALSE
3226 9.846886e-01 FALSE 0.1644375539 FALSE
3227 9.848765e-01 FALSE 0.9195481597 FALSE
3228 9.850378e-01 FALSE 0.1959917194 FALSE
3229 9.850378e-01 FALSE 0.3072014911 FALSE
3230 9.850378e-01 FALSE 0.6880813836 FALSE
3231 9.850378e-01 TRUE 0.4715424025 FALSE
3232 9.850378e-01 FALSE 0.8208335989 FALSE
3233 9.858407e-01 TRUE 0.1657616048 FALSE
3234 9.858407e-01 TRUE 0.1830376318 FALSE
3235 9.858407e-01 TRUE 0.8889980846 FALSE
3236 9.859879e-01 FALSE 1.5293082131 FALSE
3237 9.860329e-01 FALSE 0.9423445351 FALSE
3238 9.860329e-01 TRUE 1.2269859497 FALSE
3239 9.860329e-01 FALSE 0.4709515767 FALSE
3240 9.861940e-01 FALSE 0.7060878510 FALSE
3241 9.864562e-01 FALSE 0.6322491478 FALSE
3242 9.867703e-01 TRUE 0.6334830160 FALSE
3243 9.867703e-01 TRUE 0.0175310330 FALSE
3244 9.871844e-01 TRUE 0.7601603750 FALSE
3245 9.871844e-01 TRUE 0.5349537103 FALSE
3246 9.872469e-01 FALSE 0.4954358280 FALSE
3247 9.874605e-01 TRUE 0.0014104384 FALSE
3248 9.874605e-01 FALSE 0.0974428150 FALSE
3249 9.874895e-01 FALSE 0.3522540242 FALSE
3250 9.888887e-01 TRUE 2.0030018432 TRUE
3251 9.892688e-01 FALSE 0.1932264613 FALSE
3252 9.897040e-01 TRUE 0.2972847251 FALSE
3253 9.897040e-01 FALSE 1.0440005271 FALSE
3254 9.897040e-01 FALSE 0.0245098280 FALSE
3255 9.897040e-01 FALSE 2.2241325840 TRUE
3256 9.897296e-01 TRUE 0.2830228052 FALSE
3257 9.910911e-01 TRUE 0.4141178091 FALSE
3258 9.913235e-01 FALSE 0.1819096659 FALSE
3259 9.914644e-01 TRUE 0.3922732274 FALSE
3260 9.930230e-01 FALSE 0.1067284155 FALSE
3261 9.932506e-01 FALSE 0.7738306014 FALSE
3262 9.933680e-01 TRUE 2.3054228706 TRUE
3263 9.934303e-01 FALSE 0.0858781743 FALSE
3264 9.936857e-01 FALSE 0.0989061756 FALSE
3265 9.937611e-01 TRUE 2.5275972523 TRUE
3266 9.940434e-01 TRUE 0.7500490988 FALSE
3267 9.955052e-01 FALSE 0.0387858918 FALSE
3268 9.955410e-01 FALSE 0.2772995863 FALSE
3269 9.955410e-01 TRUE 0.3124897474 FALSE
3270 9.955435e-01 TRUE 0.0420184780 FALSE
3271 9.955435e-01 TRUE 0.3735223372 FALSE
3272 9.958267e-01 FALSE 0.6691625373 FALSE
3273 9.981702e-01 TRUE 1.0414368237 FALSE
3274 9.988664e-01 TRUE 0.6910868588 FALSE
3275 9.991413e-01 TRUE 0.3108380903 FALSE
3276 9.991413e-01 FALSE 0.0990713527 FALSE
3277 9.991413e-01 FALSE 0.2409690657 FALSE
3278 9.991413e-01 FALSE 0.6995974284 FALSENew_RNA_PRO_DF <- New_RNA_PRO_DF %>% mutate(Lower_quant = New_RNA_PRO_DF$delta_logFC < quantile(x = New_RNA_PRO_DF$delta_logFC , 0.05))
New_RNA_PRO_DF uniprotswissprot hgnc_symbol RNA_LogFC RNA_Pval Pro_LogFC
1 Q15327 ANKRD1 0.5423696485 3.495016e-01 -3.5538167761
2 O76021 RSL1D1 -0.3165324128 9.036930e-02 -2.1410928975
3 Q96LW7 CARD19 -0.3762588406 1.269744e-01 -1.6342957224
4 Q969Q1 TRIM63 -0.6881603653 1.389441e-01 -4.3423803749
5 P19388 POLR2E 0.1833535360 1.788005e-01 -1.1658966201
6 O43159 RRP8 0.0018779486 9.922191e-01 -2.1096892264
7 Q6EMK4 VASN -1.0133534707 2.813836e-02 2.3724491682
8 P17844 DDX5 -0.7407595340 7.355961e-06 -1.1425406345
9 Q96PU8 QKI 0.8749065610 8.348710e-04 -2.1455298252
10 Q14498 RBM39 0.2549266523 2.249342e-01 -0.8019789647
11 P67809 YBX1 -0.5089170511 3.434736e-03 -1.1045436713
12 Q9BQG0 MYBBP1A 0.5716789901 4.860616e-02 -2.2554253126
13 P17480 UBTF -0.2859211398 2.180101e-01 0.7861550384
14 Q13641 TPBG -1.2104107982 2.462399e-03 1.3614453777
15 P48634 PRRC2A 0.7258176554 6.107409e-05 -1.0858313049
16 Q92841 DDX17 1.0249205760 1.803967e-05 -0.7539368895
17 Q4G0J3 LARP7 0.2871172108 2.958777e-01 -0.7752299178
18 P78347 GTF2I 0.1886927212 1.309096e-01 -0.7435322555
19 Q02818 NUCB1 0.2009846164 3.514145e-01 -2.3955560537
20 Q00341 HDLBP 0.1728733945 4.730758e-01 -0.9058215272
21 Q13123 IK -0.0645533917 6.866371e-01 -1.1338838135
22 Q92522 H1-10 0.5329391054 8.572555e-03 -1.6536207267
23 Q14980 NUMA1 0.2147599937 3.527295e-01 -1.2192370415
24 Q14694 USP10 0.5831468596 8.741223e-08 -0.7674689571
25 Q2TAY7 SMU1 -0.2784190109 5.782096e-03 -0.7632109180
26 Q9NR30 DDX21 0.1249955267 6.201663e-01 -1.0206069551
27 O60427 FADS1 -0.1040094213 5.328441e-01 -1.2083869980
28 Q9P258 RCC2 -1.0866075184 4.199620e-04 1.7059490390
29 Q9Y6M5 SLC30A1 -1.8426913753 5.128952e-11 1.1382005458
30 Q9BVP2 GNL3 0.5743682342 5.357130e-04 -1.5081799250
31 Q9P0V3 SH3BP4 0.0942406107 7.300890e-01 -1.5653815562
32 Q6P5R6 RPL22L1 2.1440916090 3.626716e-06 -1.8797159229
33 Q92934 BAD 0.6354167891 1.824699e-02 -1.2351650877
34 Q86XP3 DDX42 -0.1455115793 3.521690e-01 -0.7285835498
35 O95864 FADS2 1.8763059331 2.691634e-08 -2.6174073619
36 Q9NZB2 FAM120A 1.2006566587 6.991516e-09 -1.0158315089
37 Q9UQE7 SMC3 0.5524711623 9.667542e-04 -1.4794349461
38 Q6P1J9 CDC73 0.3520036546 9.455214e-02 -0.7979336434
39 P16989 YBX3 -2.1656880461 3.985001e-14 -2.7782295557
40 Q9BZK7 TBL1XR1 0.1495431334 5.563774e-01 -0.6448869669
41 P08865 RPSA 0.0537509777 8.534899e-01 -0.6951266140
42 P26640 VARS1 0.2861313217 8.598609e-02 0.5742911993
43 Q96T58 SPEN -0.1889594124 4.670353e-01 1.2393881736
44 Q13151 HNRNPA0 0.2808603380 6.222551e-02 -0.7134418171
45 Q9Y2X3 NOP58 0.1478492848 2.800142e-01 0.6514755296
46 Q13451 FKBP5 -1.1939860867 1.003869e-03 0.7026843452
47 Q9UKA9 PTBP2 0.5104961052 6.227976e-02 -0.7576536433
48 P23434 GCSH 0.3253055817 2.167016e-01 0.9639278116
49 Q9Y333 LSM2 0.4165739498 9.885059e-02 -1.6242843304
50 Q53EP0 FNDC3B -0.3467806595 2.628028e-01 -1.4507298032
51 P62906 RPL10A 0.1085318331 6.383740e-01 -0.9477995132
52 P49711 CTCF -0.3667183065 2.640275e-02 -0.7460068993
53 P42285 MTREX 0.3220399833 4.353403e-02 -0.9617635928
54 Q16718 NDUFA5 0.3375636380 3.512106e-01 -0.6128746798
55 P62854 RPS26 -0.0594327323 8.141256e-01 -1.7373368214
56 Q9BQ39 DDX50 -0.6460429567 1.338170e-03 -1.1157407297
57 P62750 RPL23A -0.5370063453 1.083308e-03 -1.1141546927
58 Q9H2P0 ADNP 0.5623371965 3.959623e-05 -1.0743673769
59 Q49A26 GLYR1 -0.1064954776 4.887237e-01 0.8520902429
60 Q9UQB8 BAIAP2 -1.6114954212 1.724253e-04 1.1594641852
61 Q96L96 ALPK3 -0.0192366895 9.552033e-01 -1.7454620125
62 P62753 RPS6 0.2998923006 1.630510e-01 -0.6301099885
63 P16403 H1-2 -2.0059097186 5.623946e-11 -1.5769850831
64 P62273 RPS29 -0.3122428969 2.583113e-01 -0.7268629014
65 Q99536 VAT1 0.3685522223 2.869995e-01 0.7708229050
66 Q06136 KDSR -1.5154715177 1.182475e-08 0.7405558040
67 Q9UQ35 SRRM2 0.0665815693 8.060578e-01 -0.5903700138
68 Q96RU2 USP28 1.1205263279 1.247180e-06 -0.8072247663
69 P61254 RPL26 -0.1634115532 5.189082e-01 -0.8148623788
70 Q14728 MFSD10 0.2303285416 3.155888e-01 0.7768860215
71 Q9H1E3 NUCKS1 -0.2524100387 9.341759e-02 0.9093433795
72 Q86U42 PABPN1 -0.1201465652 5.446108e-01 -0.6371784527
73 P61313 RPL15 -0.2777577556 6.150198e-02 -0.5116069160
74 Q01780 EXOSC10 0.6078974986 5.992892e-06 -1.8332257421
75 P46782 RPS5 0.1669044709 4.352819e-01 -0.7266249638
76 Q9HCM4 EPB41L5 -0.3657468712 1.615621e-01 0.8163123746
77 P30876 POLR2B -0.4105165460 5.497988e-03 -1.0153940278
78 P39880 CUX1 0.2712355427 1.232083e-01 -0.6669134126
79 Q9NQT5 EXOSC3 -0.0591001711 7.319892e-01 -0.9054903012
80 P62280 RPS11 -0.0437036854 8.521183e-01 -0.6059548196
81 P62701 RPS4X -0.1338643168 7.047699e-01 -0.5729549732
82 Q92747 ARPC1A 0.2732384855 5.453804e-02 0.6126517330
83 P36578 RPL4 0.2460868547 1.199925e-01 -0.4568522015
84 P62888 RPL30 -0.0155926213 9.563555e-01 -0.6160229343
85 Q5QJ74 TBCEL -1.4662009183 5.426043e-12 -1.1986896135
86 O75787 ATP6AP2 -0.6821280852 1.086495e-01 1.6934062614
87 P49207 RPL34 -0.1211116692 6.382085e-01 -0.9596894143
88 Q9P0M6 MACROH2A2 0.4935875694 3.905499e-07 1.6001832065
89 Q6Y7W6 GIGYF2 -0.1024997998 5.643843e-01 -0.9044508349
90 Q7Z739 YTHDF3 -0.5222794108 3.378136e-04 -0.7250445918
91 Q8NC51 SERBP1 0.2679755058 7.545723e-02 -0.8540143136
92 P18621 RPL17 -0.5348164756 6.742014e-03 -0.6967076722
93 O00461 GOLIM4 -0.1540253416 6.585118e-01 -0.4757964569
94 P46783 RPS10 -0.5896367473 1.341147e-02 -0.9888508824
95 P19338 NCL -0.3814844249 5.133478e-02 -0.5172166796
96 P53396 ACLY -1.2193091206 6.052200e-03 1.0062251308
97 Q99459 CDC5L 0.2154638895 8.196734e-02 -0.6906765081
98 Q9Y5S2 CDC42BPB -0.2852836767 1.334011e-01 -0.5251120289
99 Q9Y2I6 NINL 0.2586382080 2.314292e-01 0.5208548082
100 O60292 SIPA1L3 0.0896779474 6.332390e-01 1.2411170961
101 P61513 RPL37A 0.1556896334 5.251190e-01 -0.5882082097
102 Q13509 TUBB3 -1.2463074828 4.480636e-02 0.7849629140
103 Q9NVP1 DDX18 0.2250775953 7.684463e-02 -0.6777723393
104 P62263 RPS14 0.1186696646 6.268403e-01 -0.6026084568
105 P16220 CREB1 0.1002609718 4.352588e-01 -0.5031254586
106 Q9UKU7 ACAD8 0.1364006897 3.756701e-01 0.5589429736
107 P34932 HSPA4 -0.6130166200 8.478545e-05 0.5788276899
108 P83731 RPL24 0.0199956587 9.315324e-01 -0.5543597613
109 P62249 RPS16 0.2841806551 2.946914e-01 -0.6667823795
110 P25398 RPS12 -0.3797426277 1.522246e-01 -0.5878505606
111 Q12983 BNIP3 0.5236624690 5.832608e-01 -1.1241955717
112 P07996 THBS1 0.9957149963 1.485370e-01 -1.6006476533
113 Q14966 ZNF638 0.0470025052 8.313867e-01 -0.7779107967
114 P17302 GJA1 1.0024333545 6.579793e-03 -1.1116578520
115 Q9UBG0 MRC2 -0.0485667744 9.275443e-01 -1.0789245230
116 P55769 SNU13 0.4032101161 3.799754e-02 0.5414058709
117 P21453 S1PR1 1.4274102716 2.512511e-07 -1.0074850656
118 P15529 CD46 -1.4098171521 4.689571e-07 0.5800084020
119 P83881 RPL36A 0.4502476157 9.321517e-02 -0.7844961130
120 Q06830 PRDX1 -0.9340143668 5.122866e-02 0.5174185908
121 Q9NUP9 LIN7C -0.3853882539 1.204831e-01 -0.6427814586
122 P08708 RPS17 -0.1856452739 4.429504e-01 -0.8002218256
123 P62269 RPS18 0.1069074033 6.059797e-01 -1.0084011844
124 O00541 PES1 -0.0638765453 7.365412e-01 -2.3190460799
125 P62910 RPL32 -0.0787556324 7.508022e-01 -0.7025333738
126 P50914 RPL14 0.1960652298 2.503990e-01 -0.4629932812
127 Q9NYV4 CDK12 0.3764525948 3.462818e-02 -0.6501491349
128 P61353 RPL27 -0.1297737964 5.862650e-01 -0.4807151241
129 P54764 EPHA4 -0.3959965658 9.940504e-02 1.3983624382
130 P62841 RPS15 -0.4927651457 7.587736e-03 -0.6722019865
131 P61247 RPS3A -0.4367032139 5.334327e-02 -0.5803803999
132 P62857 RPS28 -0.2735144838 6.438816e-01 -1.3991428488
133 P29558 RBMS1 -0.3008464951 3.105908e-02 -0.4794151940
134 Q99873 PRMT1 -0.0670870432 6.567542e-01 0.4642899702
135 P62424 RPL7A 0.0448473591 7.268621e-01 -0.5670129678
136 P18077 RPL35A 0.1172737360 6.081130e-01 -0.5872810025
137 Q9H307 PNN 0.4950469311 7.883106e-03 -0.7368335650
138 P06748 NPM1 0.0629947752 8.012141e-01 -0.6721264871
139 Q8IWC1 MAP7D3 0.2931146269 2.701569e-01 -0.7035432539
140 Q9NPL8 TIMMDC1 -0.3458313149 1.145294e-02 -0.5256142728
141 Q92784 DPF3 1.4622008139 2.254046e-09 -0.9494860176
142 Q9H2K0 MTIF3 -0.0604631902 7.829920e-01 -1.4597652645
143 O00571 DDX3X -0.5880584735 2.960967e-03 -0.5290939081
144 Q9BYV2 TRIM54 1.4386359326 1.550574e-02 -1.0838816024
145 P46778 RPL21 0.1378669900 5.816250e-01 -0.4880244806
146 Q9GZS1 POLR1E 1.1068653352 1.334246e-06 -0.8329828638
147 P19320 VCAM1 5.7863632154 1.134608e-08 -2.4632413096
148 P05387 RPLP2 -0.1553830106 4.149530e-01 -1.0476033013
149 P32969 RPL9 -0.3735452234 2.068902e-01 -0.4397303828
150 P82979 SARNP 0.3174775373 6.651951e-02 -0.6838448301
151 P60510 PPP4C -0.1236748345 4.315664e-01 -0.4109111435
152 Q71RC2 LARP4 -0.2273063245 1.410006e-01 -1.3241873915
153 Q13084 MRPL28 0.8271051167 3.084432e-05 -0.9432339010
154 Q6P5Q4 LMOD2 3.2175509094 5.842445e-05 -1.1211381976
155 O43660 PLRG1 0.1472372167 2.847966e-01 -0.5044680663
156 Q9H832 UBE2Z -0.7181425114 6.721573e-05 0.7271212659
157 P62851 RPS25 0.0062667403 9.805571e-01 -1.6985247921
158 P62847 RPS24 -0.5096428043 4.835569e-03 -0.5606924342
159 Q9BYN8 MRPS26 0.4978233367 1.287251e-02 -1.2591913827
160 Q9Y3Y2 CHTOP 0.2899907269 2.274058e-02 -1.3635409111
161 P11940 PABPC1 -0.3428583069 1.658003e-01 -0.4467117211
162 Q9H0S4 DDX47 0.1751222851 3.151134e-01 -1.4130213235
163 P62899 RPL31 -0.0598351306 8.425184e-01 -0.4297886272
164 Q16658 FSCN1 -0.9495832435 9.367219e-03 0.5376047849
165 Q9BXB1 LGR4 1.2805016735 5.359533e-08 -1.6471304981
166 Q13310 PABPC4 0.4333442177 1.219707e-04 -0.4220855821
167 Q68CP9 ARID2 0.6805067410 9.729348e-06 -0.5392572756
168 Q9NR56 MBNL1 0.6315622690 4.800199e-03 -1.6782527965
169 Q5BKY1 LRRC10 3.8479511258 1.373363e-08 -1.0063252056
170 O75155 CAND2 1.6911947908 1.475912e-05 -0.8070167308
171 Q12972 PPP1R8 0.1028381590 4.506624e-01 -1.2890200440
172 P62917 RPL8 0.1874298912 3.737473e-01 -0.4759712554
173 Q15758 SLC1A5 -0.7960474559 5.215009e-02 1.6055961679
174 Q9UJV9 DDX41 -0.0650175184 8.471726e-01 -0.8936118551
175 Q9H0A0 NAT10 0.5836673271 1.051245e-03 -0.8083854490
176 Q9H7H0 METTL17 0.3284008459 9.959660e-02 -0.4444226909
177 Q9Y3U8 RPL36 -0.0784290817 6.804384e-01 -1.0547820892
178 P39019 RPS19 -0.9358010869 2.615819e-06 -0.9746307783
179 P63244 RACK1 0.4945450512 3.137162e-03 -0.4428959494
180 Q12888 TP53BP1 0.7963358058 6.702687e-06 -0.5710654747
181 Q15024 EXOSC7 0.2756435422 2.117596e-01 -0.4925725531
182 P25101 EDNRA 1.1591768528 2.582678e-06 -0.4080247904
183 Q9P013 CWC15 -0.2977485608 7.896910e-02 -1.0350132316
184 Q9UNK0 STX8 1.0851469606 5.055426e-06 -0.5908648570
185 P46781 RPS9 0.1185755912 6.772641e-01 -0.5203788401
186 P98155 VLDLR 0.5641684176 3.781976e-03 -0.7958276532
187 P46776 RPL27A -0.1238618382 4.572328e-01 -0.7746361337
188 Q9NY33 DPP3 -0.0230043562 9.467111e-01 0.7104695951
189 Q9BR76 CORO1B -0.7955866668 2.205256e-03 0.5548415064
190 Q99766 DMAC2L 0.1745906472 5.356163e-01 -0.5964048840
191 Q9BQ95 ECSIT 0.6228001120 2.220967e-02 0.6415744071
192 P29401 TKT -1.6166951239 3.333491e-03 0.5151478042
193 P78396 CCNA1 -3.7597154042 3.862465e-06 -0.5207857144
194 Q9Y224 RTRAF -0.1404486080 4.739177e-01 -1.4394805400
195 P51970 NDUFA8 0.9532891926 1.007481e-03 -0.4287029276
196 Q969Q0 RPL36AL -0.0013377286 9.941708e-01 -2.5438450163
197 Q11201 ST3GAL1 -0.3704414676 1.070530e-01 -1.1179694119
198 O96013 PAK4 1.3294755471 2.005242e-09 -0.7887611969
199 Q14444 CAPRIN1 0.3399395502 1.224001e-03 -0.5416817723
200 Q13283 G3BP1 0.1174380221 4.352588e-01 -0.6991609801
201 P23396 RPS3 -0.0244107222 8.976225e-01 -0.4169526676
202 Q92520 FAM3C -0.5180705970 5.693321e-02 -0.7789476428
203 P62244 RPS15A 0.1542285851 5.678381e-01 -0.4298640795
204 P19474 TRIM21 -0.8505053089 8.767955e-04 -0.7914407893
205 P47914 RPL29 0.0097464034 9.678269e-01 -0.8915834740
206 P60866 RPS20 -0.6384526455 1.886575e-03 -0.4642474623
207 Q14839 CHD4 0.7313790878 1.083429e-05 -0.3899063239
208 Q8WUT4 LRRN4 1.1156621206 6.247524e-02 -1.7898291377
209 O75940 SMNDC1 0.0792686064 6.234391e-01 -0.9057750747
210 Q8WVM0 TFB1M 0.9067679530 1.948248e-04 -0.7050242947
211 O95433 AHSA1 0.0768270140 6.250759e-01 0.6888824932
212 Q9GZQ8 MAP1LC3B -1.2290243216 1.126835e-06 0.4997938598
213 Q8IY95 TMEM192 -0.4205827416 1.125052e-01 -0.4084318083
214 P39023 RPL3 0.3080976843 6.405062e-02 -0.4153614928
215 O43148 RNMT 0.2066377958 1.687837e-01 -0.4156445083
216 P36873 PPP1CC 0.6351661722 4.864267e-05 -0.4399589985
217 Q16555 DPYSL2 2.1706762391 1.215465e-05 0.6223084191
218 Q9UNE7 STUB1 -0.0810940217 6.652149e-01 -0.6951469188
219 Q00839 HNRNPU -0.1628177675 2.933821e-01 -0.3563229842
220 Q9UJA3 MCM8 1.6219135563 4.286690e-08 -0.4142764701
221 P04066 FUCA1 -2.1028351663 1.343373e-06 0.4469205277
222 Q13586 STIM1 -1.4102797908 8.097095e-09 0.6298863463
223 Q9P032 NDUFAF4 0.4899183878 1.103590e-01 -0.5274168749
224 Q8N3V7 SYNPO -0.9532842945 1.069135e-01 -0.7572117675
225 P02462 COL4A1 0.0703481228 8.636317e-01 -0.7414080073
226 P28799 GRN -0.4950963009 1.613259e-02 0.5931696188
227 P26373 RPL13 0.1074644094 6.335468e-01 -0.5645815732
228 P78540 ARG2 -0.0767858913 9.095050e-01 -0.5239525168
229 P27635 RPL10 0.0554514130 8.188589e-01 -0.4730751821
230 O00303 EIF3F 0.2080701424 1.182386e-01 -0.4014406815
231 P48740 MASP1 0.1574737844 7.328062e-01 -0.8551857038
232 P50895 BCAM 0.3644328300 5.301379e-01 0.3371940543
233 Q9NY27 PPP4R2 -0.0160083908 9.188219e-01 -1.0496574340
234 P15880 RPS2 -0.1256455183 5.971345e-01 -0.4052133229
235 Q8WWM7 ATXN2L -0.0787973165 6.906027e-01 -0.4028447239
236 P62266 RPS23 -0.0013911916 9.951722e-01 -0.5503947248
237 P42766 RPL35 0.0457884393 8.780237e-01 -1.3454650365
238 P78346 RPP30 0.4830240047 4.405524e-03 -0.7178325605
239 Q8TB96 ITFG1 -0.2981325990 1.560165e-01 0.8584113427
240 Q9H2W6 MRPL46 0.2279096678 4.035797e-01 -0.8109774106
241 Q16851 UGP2 0.0029359651 9.902724e-01 0.4303957377
242 Q96HP4 OXNAD1 0.5731209896 1.325697e-02 -0.3870496758
243 O14735 CDIPT -0.8058775904 3.844745e-07 0.6227885873
244 P08758 ANXA5 -0.8925552947 9.041284e-03 0.6197817327
245 Q9NYY8 FASTKD2 0.9049356525 1.243965e-04 -0.5852458646
246 P46779 RPL28 -0.2034809793 2.585471e-01 -0.3987696346
247 Q9Y3D9 MRPS23 -0.0568288787 8.301168e-01 -0.6067669038
248 P54819 AK2 0.3648377403 1.990512e-02 -0.4920832708
249 Q9Y3T9 NOC2L -0.4889902843 5.286748e-05 -1.6245155473
250 P30050 RPL12 -0.3102467457 2.019839e-01 -0.4647297615
251 Q5RKV6 EXOSC6 0.4047865698 1.017811e-01 -1.3849747643
252 O95104 SCAF4 -0.3301704317 7.597994e-02 -0.9055782502
253 Q13045 FLII 0.2513858624 1.021944e-01 -0.3767310091
254 Q9UEU0 VTI1B 0.2642975454 1.130288e-01 -0.8768551571
255 Q9H0D6 XRN2 -0.1837978535 1.756149e-01 -0.4686270379
256 Q9P0M9 MRPL27 0.0593475532 8.539815e-01 -0.6511987136
257 O60828 PQBP1 0.4900046328 7.052813e-05 -0.8124911955
258 Q5VT52 RPRD2 0.4550760007 5.273264e-02 -1.0233266627
259 P82932 MRPS6 -1.4505446953 5.540140e-06 -0.4358097247
260 O60832 DKC1 0.6947629385 6.973185e-05 0.4659275185
261 Q15061 WDR43 -0.7812836834 1.716509e-06 1.1347468039
262 Q5T481 RBM20 0.8819416375 2.811629e-04 -0.4517640243
263 Q9H511 KLHL31 2.2783900339 2.371431e-05 -1.3304992746
264 Q9HD26 GOPC 0.0008763120 9.958031e-01 -1.2928101198
265 Q13885 TUBB2A 0.0597056068 9.023055e-01 0.4790130748
266 Q9BYD3 MRPL4 0.8362775985 7.678685e-05 -0.6339303010
267 Q02543 RPL18A -0.2891848150 1.617336e-01 -0.3894487283
268 Q9UBE0 SAE1 0.8181978469 5.830672e-07 -0.7810261501
269 P62316 SNRPD2 0.3020759116 2.086768e-01 -0.4206857485
270 P52907 CAPZA1 -0.2164052920 2.503990e-01 0.3113855959
271 Q9Y676 MRPS18B 0.7233214718 2.558969e-04 -0.6528927231
272 P01130 LDLR 0.1198290011 7.939456e-01 -2.5854233520
273 P62633 CNBP 0.3989750262 3.906168e-02 -0.8721945896
274 Q9Y6M9 NDUFB9 0.3237702457 2.458497e-01 -0.6729555239
275 P28370 SMARCA1 0.4981713943 9.046414e-03 -0.6445959769
276 P62913 RPL11 0.0216580344 9.178005e-01 -0.3456255710
277 P20908 COL5A1 0.0077279234 9.902724e-01 -0.9037705832
278 Q9Y4D1 DAAM1 -0.1254258437 4.109070e-01 -0.4805785925
279 P13805 TNNT1 1.0068783914 2.636288e-03 -0.9512257565
280 P62241 RPS8 -0.1587323616 3.394358e-01 -0.4539554775
281 O15270 SPTLC2 0.7253863974 2.553260e-03 -0.8836958713
282 Q5SY16 NOL9 0.1816399045 2.563003e-01 0.7251262997
283 Q9NZJ7 MTCH1 -0.2938380442 4.532038e-02 0.3461815482
284 Q96SI9 STRBP -0.1609476687 2.137362e-01 -1.2108323950
285 Q96GC5 MRPL48 -0.1443070528 5.111842e-01 -0.3919758789
286 P26641 EEF1G -0.0689973087 7.246135e-01 0.3608725244
287 Q96E52 OMA1 0.8801346479 3.115714e-04 -0.5609662542
288 Q96A72 MAGOHB 0.9207700009 1.230800e-04 -1.5596755214
289 P06396 GSN -0.1817545324 6.809838e-01 0.5182610885
290 P62745 RHOB -0.3920291281 1.600153e-01 -0.6805853306
291 Q8WVV9 HNRNPLL -0.6536880337 1.409387e-03 -1.7099407745
292 Q99496 RNF2 0.1769816439 3.544101e-01 -0.3722565806
293 Q12974 PTP4A2 -0.1225014446 4.621706e-01 -0.5389948290
294 Q6PKG0 LARP1 0.2805042938 8.462617e-02 -0.7611523705
295 Q9BRQ6 CHCHD6 1.6230743804 8.745341e-09 -0.6735268248
296 P31483 TIA1 0.2743497218 2.502705e-01 -0.5595298142
297 Q14137 BOP1 0.6993891592 8.666290e-06 -1.0527081619
298 O75427 LRCH4 0.6380826733 4.480257e-07 -0.8247443289
299 Q5T8D3 ACBD5 0.1846336387 2.135512e-01 -0.4910145082
300 O75822 EIF3J 0.0944707624 5.053986e-01 -1.1509904452
301 P51116 FXR2 -0.0514965589 7.173752e-01 -0.3192980472
302 Q92797 SYMPK -0.4353086253 7.972376e-04 0.4093278008
303 P36405 ARL3 0.2263495682 2.345075e-01 0.9012283787
304 P12277 CKB 0.0802026196 7.857749e-01 0.4928765668
305 Q96C36 PYCR2 -0.2511283080 4.619373e-02 0.4938772506
306 Q9HCD6 TANC2 0.6996840112 4.362276e-02 -0.8589839307
307 Q9Y2R9 MRPS7 0.1842542118 3.419440e-01 -0.7858436518
308 Q9HAT2 SIAE -0.1645405316 4.858789e-01 0.3056520776
309 Q9P2F8 SIPA1L2 0.1373712624 6.224173e-01 -0.6524360656
310 Q68E01 INTS3 0.5155336479 2.088983e-03 -0.9403976021
311 Q16850 CYP51A1 0.8873943450 3.428984e-04 -0.5381837521
312 Q14789 GOLGB1 0.0869764249 6.403854e-01 -0.4014819772
313 Q5T8P6 RBM26 0.1168519656 3.847801e-01 -0.7024127638
314 Q9BTD8 RBM42 -0.2342168959 4.429647e-01 -0.7436159729
315 Q92900 UPF1 -0.5270460842 1.085298e-02 -0.3735692039
316 P68032 ACTC1 2.1954078615 9.556916e-06 0.3587171349
317 O14949 UQCRQ -0.2261677317 5.375570e-01 -0.4731493370
318 Q9P2D3 HEATR5B -0.2164620244 2.458497e-01 0.8062594119
319 P07437 TUBB 2.4539199959 1.346482e-12 0.3844328233
320 P43155 CRAT -0.5402284509 1.146006e-02 0.3269702218
321 Q92945 KHSRP -0.1528435146 2.703341e-01 -0.3122001624
322 O60264 SMARCA5 0.5166142102 1.285809e-05 -0.3950351402
323 Q969V5 MUL1 0.2728545634 4.831754e-02 -0.8109338807
324 P46063 RECQL 0.1223529613 7.581931e-01 0.5941972155
325 P13987 CD59 -1.0162186604 2.461916e-04 0.4092945541
326 P84090 ERH 0.1966450727 1.644475e-01 -0.6396746570
327 Q71U36 TUBA1A 1.4021216608 1.098121e-05 0.4290536337
328 Q9BUF5 TUBB6 -0.7276692060 2.668735e-03 0.4609134230
329 Q5VZP5 STYXL2 1.2515035896 2.189358e-02 -0.5405508547
330 P80303 NUCB2 0.4203168918 2.927701e-02 -1.2165969840
331 Q92667 AKAP1 0.9545320217 1.026714e-05 -0.8204931203
332 P63220 RPS21 -0.0191404628 9.547250e-01 -0.9255878960
333 Q96JC1 VPS39 -0.4699787619 3.935340e-04 0.6779912933
334 P46976 GYG1 0.0078442435 9.814166e-01 0.6244557293
335 P63272 SUPT4H1 -0.5384631514 1.016012e-05 -0.9228884654
336 P62195 PSMC5 -0.0087478083 9.536399e-01 0.4573170199
337 Q08289 CACNB2 1.0870390762 2.312329e-03 -0.4092162305
338 P35556 FBN2 0.7100883122 2.330280e-02 -0.5225697573
339 P54709 ATP1B3 -0.3089159007 3.849201e-01 0.3512522227
340 O14979 HNRNPDL 1.0306517805 5.107003e-07 -0.2924607292
341 O60341 KDM1A 0.0872847729 5.153440e-01 -0.3443014115
342 Q15181 PPA1 0.4079346900 2.491160e-01 0.9516982601
343 Q96AE4 FUBP1 0.9363571166 5.536343e-08 -0.3770316600
344 Q8WZA1 POMGNT1 -0.0109817447 9.529130e-01 -0.5457677543
345 Q9NRX2 MRPL17 0.8605785394 3.140535e-05 -1.0740722708
346 P55042 RRAD 0.7688042127 1.231594e-01 -0.4036987232
347 P18124 RPL7 -0.1367387601 5.732436e-01 -0.3741115347
348 O75367 MACROH2A1 -0.4465099799 1.059118e-03 0.3524598606
349 Q8WX93 PALLD 0.4014122865 2.124664e-02 -0.5543441210
350 Q07960 ARHGAP1 0.9021028730 1.856772e-04 0.2922541606
351 P40429 RPL13A -0.2035821453 2.615269e-01 -0.3283224071
352 P52701 MSH6 1.0272848441 9.966054e-06 0.7948613613
353 P30566 ADSL 0.2364629204 4.556902e-02 0.5548074412
354 P46100 ATRX -0.0195891859 9.214757e-01 0.4591933947
355 P55789 GFER 0.1714220170 3.846111e-01 -1.4332328192
356 P41229 KDM5C -0.1194961205 7.352198e-01 1.6930720368
357 Q4U2R6 MRPL51 -0.1438654574 4.516234e-01 -0.8497542868
358 Q9Y520 PRRC2C 0.0744350860 6.724141e-01 -0.4122738367
359 Q13868 EXOSC2 0.9940876365 1.113388e-07 -0.6709261237
360 O60504 SORBS3 1.3006950994 1.021733e-07 -0.4752360642
361 Q01668 CACNA1D 0.3771640882 3.578012e-01 0.4155162081
362 Q14195 DPYSL3 0.8827320969 3.411693e-03 0.3862646005
363 P29218 IMPA1 -0.3686568123 8.875258e-02 0.5414487333
364 Q13416 ORC2 0.6384997150 4.257490e-04 -0.6343380016
365 P63208 SKP1 -0.3882136335 2.127564e-02 -0.5720193097
366 O60749 SNX2 -0.5193840648 9.628923e-04 0.4210399720
367 P60520 GABARAPL2 -0.5980287446 2.891437e-03 0.3000299316
368 P27105 STOM -1.2455487476 3.287804e-07 -0.4290548550
369 Q2M3C7 SPHKAP 3.1667088674 1.529116e-03 -0.8221551990
370 P28838 LAP3 -0.3104866216 5.130279e-02 0.3032390802
371 Q13098 GPS1 -0.0450396127 7.334863e-01 -0.6335783250
372 Q14165 MLEC -0.6798477294 2.428190e-03 0.3464119029
373 Q8TAQ2 SMARCC2 0.2258610407 1.727956e-01 -0.3737634055
374 P51784 USP11 -0.6450091305 3.606982e-03 0.8161837895
375 Q96KR1 ZFR 0.1049359300 6.498938e-01 -0.3748355103
376 Q7Z2W9 MRPL21 0.4048853397 1.310670e-01 -0.6916203087
377 P56385 ATP5ME 0.0232226747 9.522307e-01 -1.0637270214
378 Q9Y5B9 SUPT16H 0.2030047055 2.310478e-01 0.2954668383
379 Q9NVM9 INTS13 0.3988358940 9.932321e-04 -1.3026924690
380 Q92598 HSPH1 -0.7613134255 1.436923e-04 0.3804315943
381 Q9BT78 COPS4 -0.0195633515 9.370910e-01 -1.0558452099
382 P37108 SRP14 0.2726095961 4.252475e-01 -0.6169511964
383 P05204 HMGN2 -0.0788204280 7.571384e-01 -1.2085669392
384 O14656 TOR1A -0.8186753412 3.559545e-04 0.4511341811
385 Q3ZAQ7 VMA21 -0.4170151266 1.182572e-02 -0.4151625218
386 P13807 GYS1 -0.1264663904 7.073062e-01 0.4516558156
387 Q9P015 MRPL15 1.2789894244 1.319160e-04 -0.5904530367
388 Q15043 SLC39A14 1.5983854558 3.239786e-09 -0.7832229949
389 Q9Y5Q9 GTF3C3 0.4779158425 2.972656e-02 -1.0813404482
390 P17655 CAPN2 -0.0749915165 8.344448e-01 0.2934613225
391 P09661 SNRPA1 0.6417607018 9.520794e-03 -0.5332923877
392 Q16775 HAGH -0.1962403378 3.290442e-01 0.3476464592
393 Q9ULC3 RAB23 -0.0549202741 8.028234e-01 0.4260306931
394 Q96AA3 RFT1 0.3812161119 1.349483e-01 1.0958445515
395 Q9NQW7 XPNPEP1 0.2651260227 5.654978e-03 0.4582743679
396 Q07666 KHDRBS1 0.3353122796 2.495134e-03 -0.4688445046
397 Q13308 PTK7 0.0071098280 9.807059e-01 0.4373290166
398 P68104 EEF1A1 -0.2470038476 2.381038e-02 0.3181740149
399 Q9H6H4 REEP4 1.0575919641 1.259830e-03 0.4640746350
400 Q8N201 INTS1 -0.1771978166 2.839828e-01 -0.8975844927
401 P43007 SLC1A4 0.2281585816 5.039942e-01 1.8802482838
402 Q8TCC3 MRPL30 0.4680122762 2.163909e-03 -0.6584219344
403 Q8WV74 NUDT8 -0.9970464088 1.154943e-03 -0.5504330912
404 Q9NXV6 CDKN2AIP 0.1468676663 5.083058e-01 -0.4972596863
405 P12429 ANXA3 0.3652194368 1.433188e-01 0.3176720787
406 P23229 ITGA6 -0.6257620402 1.400451e-01 0.6595635443
407 Q9UP95 SLC12A4 -1.4325877990 5.177903e-07 -0.4635346249
408 Q9BXX0 EMILIN2 -0.0783713227 6.822287e-01 -0.6344854439
409 Q71UI9 H2AZ2 0.6135690089 2.147418e-04 -0.4301336551
410 Q9Y2W2 WBP11 0.8287414540 4.007254e-04 -0.4028048673
411 Q15637 SF1 1.2527316777 4.090712e-11 -0.4581816870
412 P84098 RPL19 -0.2385906121 9.704783e-02 -0.4721135303
413 Q96EL2 MRPS24 0.3574359187 3.768453e-01 -0.4131804042
414 Q14197 MRPL58 0.2719690900 2.256413e-01 -0.3695335464
415 Q9Y3Q4 HCN4 0.4662549138 6.640458e-02 -0.7093931841
416 Q08379 GOLGA2 0.8215388821 5.563077e-06 -0.4895793901
417 P51532 SMARCA4 0.5154207060 4.659437e-03 -0.3179279487
418 P13645 KRT10 0.4673739666 6.983123e-02 -2.0029629530
419 Q92905 COPS5 0.5404312642 4.092852e-03 0.4018375134
420 Q9NTI2 ATP8A2 -1.4022203539 5.365945e-03 0.4929770512
421 P55265 ADAR -0.1619696324 5.258018e-01 -0.6610507874
422 O00291 HIP1 0.9405567383 5.841820e-05 -0.3009509003
423 Q99613 EIF3C 0.3928267492 1.139536e-01 -0.3061523124
424 P85037 FOXK1 0.1520530566 4.664245e-01 -0.8461871169
425 Q96JJ7 TMX3 0.2736242923 3.247071e-01 0.3344933002
426 Q6IN84 MRM1 -0.3747478403 1.138166e-01 -0.6194351122
427 Q8N5M1 ATPAF2 -0.9191643340 1.050751e-08 0.8283158927
428 Q9ULA0 DNPEP 0.5047163836 4.193959e-02 0.3580605778
429 P62081 RPS7 0.0690921127 7.880325e-01 -0.3610348386
430 Q8IWS0 PHF6 0.4902379537 4.041485e-02 -0.6440290831
431 P15848 ARSB -0.4096872277 7.803900e-02 0.3891627085
432 Q9BQQ3 GORASP1 0.4132613005 5.365424e-04 -0.7132660761
433 P22087 FBL 0.8289703912 4.178859e-04 0.4594797427
434 Q12996 CSTF3 -0.6960501727 3.031616e-03 0.3031950790
435 P55884 EIF3B -0.4618877814 4.749722e-03 -0.3126922986
436 P07195 LDHB 0.2491087735 3.948683e-01 0.3203974681
437 Q9UN86 G3BP2 -0.7040184543 6.113209e-07 -0.2989675130
438 P23468 PTPRD 1.0787928665 9.758776e-04 -0.9630380004
439 P54920 NAPA -0.8502220740 1.077099e-08 -0.6048193942
440 P02452 COL1A1 0.6721815204 5.358371e-01 -0.8630373614
441 Q16531 DDB1 -0.3948834173 2.522025e-03 0.2763074102
442 P68371 TUBB4B 0.3006574067 1.056926e-01 0.3750467234
443 P49458 SRP9 0.2669696641 1.234128e-01 -1.0415756021
444 P56537 EIF6 -0.1902817074 1.307247e-01 0.6675807342
445 Q96B26 EXOSC8 2.0101417868 2.989705e-13 -0.6792508671
446 P68366 TUBA4A -1.4354288035 2.628266e-02 0.4272030385
447 P62277 RPS13 -0.2690662375 1.640769e-01 -0.3846046816
448 Q16822 PCK2 -0.1756835712 6.825087e-01 0.4709793965
449 Q5BKZ1 ZNF326 0.1951961438 3.308689e-01 -0.3647787281
450 Q13263 TRIM28 0.0962837324 5.528096e-01 -0.2937293605
451 Q9BVK6 TMED9 0.3155895074 3.025056e-01 0.4827264623
452 P23528 CFL1 -0.5758998949 3.722646e-03 0.3117478150
453 Q8IX01 SUGP2 -0.0137509656 9.191644e-01 -0.2795046931
454 Q9BY50 SEC11C -0.3268293953 3.941064e-01 -1.2684329185
455 Q16787 LAMA3 -0.6907573539 2.712123e-01 -0.3462892463
456 Q92743 HTRA1 0.2307052769 5.141306e-01 0.8623326478
457 O60506 SYNCRIP 0.1590813816 2.914142e-01 -0.3910241522
458 Q07020 RPL18 -0.0471146593 7.870350e-01 -0.2858289428
459 Q96QZ7 MAGI1 0.5570774145 2.358907e-04 -0.4339758253
460 P35637 FUS 0.3390490981 3.724655e-02 -0.2990647406
461 P09012 SNRPA 0.1910245206 2.180101e-01 -0.3090219578
462 Q9H1E5 TMX4 -1.4146185712 1.891611e-08 0.3043317235
463 O14776 TCERG1 0.7901206455 2.620191e-09 -0.3458759592
464 O96000 NDUFB10 1.0000141615 5.569011e-04 -0.4227285183
465 P60468 SEC61B -0.2153534445 4.482293e-01 -0.5599036128
466 P82914 MRPS15 0.0752106813 6.496023e-01 -0.8500467295
467 Q13247 SRSF6 0.5386303730 5.001146e-03 -0.2604375079
468 Q14152 EIF3A 0.1726139814 2.890248e-01 -0.3089986079
469 P56589 PEX3 0.6372032138 5.751769e-04 -0.9449411391
470 Q8TDN6 BRIX1 0.3654738576 5.006356e-02 -0.7560440425
471 Q96DB5 RMDN1 -0.1772339474 4.038820e-01 -0.4723676141
472 Q9Y3A3 MOB4 0.0255375791 9.528946e-01 -0.3440229284
473 Q92800 EZH1 -0.4801464253 1.969336e-02 0.3908564702
474 Q6PJT7 ZC3H14 0.4034031224 2.096873e-03 -0.4874957222
475 Q8IZV5 RDH10 -2.1353159089 2.660668e-13 1.1706138848
476 P04632 CAPNS1 0.2368317063 1.936450e-01 0.2772049278
477 Q9NR34 MAN1C1 0.4481741366 6.484816e-02 -0.9665615416
478 P19404 NDUFV2 0.6998375558 2.028573e-03 -0.3781730368
479 Q6NZY4 ZCCHC8 0.2875460765 1.407064e-01 -0.4962457368
480 P38919 EIF4A3 -0.5451352258 2.358548e-03 -0.3684189605
481 Q6PIU2 NCEH1 -1.3116846487 1.526136e-03 0.5851131103
482 Q29RF7 PDS5A 0.6470874046 1.134430e-06 -0.5547108799
483 Q13202 DUSP8 0.4228096168 3.353131e-01 1.8187243965
484 Q8IUH4 ZDHHC13 0.5036690751 2.816376e-02 -0.5153855648
485 P0DMV9 HSPA1B -0.8663812989 2.021490e-02 0.2708637003
486 P07305 H1-0 -1.2559973086 2.904490e-02 -1.0334128888
487 P50750 CDK9 -0.7910846063 2.340011e-07 0.2855567380
488 Q99653 CHP1 0.1309733547 2.945199e-01 -0.4448151817
489 Q99643 SDHC -0.0968659127 5.549480e-01 0.4862583138
490 P42677 RPS27 -0.6445649133 1.414077e-02 -0.3351396054
491 O95169 NDUFB8 0.0506719816 8.751558e-01 -0.4606033708
492 Q9HCD5 NCOA5 0.2887085858 1.446025e-01 -0.3506594591
493 P18583 SON -0.0818892058 5.755145e-01 -0.9153020232
494 Q00059 TFAM 0.2011667397 2.513114e-01 -0.7790856934
495 O95218 ZRANB2 -0.0456755950 7.610537e-01 0.3083065194
496 Q9Y2X7 GIT1 -1.4967307021 1.466811e-10 0.3132612547
497 Q96HD1 CRELD1 0.3642374314 6.328671e-02 0.2715033937
498 P78559 MAP1A 0.4226387467 2.747778e-01 0.3942175556
499 O43395 PRPF3 0.2201058117 3.849201e-01 -0.5403943652
500 Q13347 EIF3I -0.2477456755 8.042413e-02 -0.2716999379
501 Q86UU1 PHLDB1 -0.1668358344 5.754920e-01 0.2530908683
502 O76031 CLPX 0.0035449924 9.832379e-01 -0.3107116887
503 Q9NWB1 RBFOX1 1.1281874868 1.169248e-01 -0.9501738753
504 Q9H2G2 SLK 0.0526281272 8.608871e-01 0.3681217777
505 Q96QE5 TEFM -0.2918104476 2.138701e-01 -0.4496117216
506 P19429 TNNI3 2.3467024412 2.301703e-05 -0.9714665218
507 Q15366 PCBP2 0.0030323143 9.886746e-01 -0.3037069974
508 O75616 ERAL1 -0.3518307158 5.553771e-03 -0.9408901443
509 P61764 STXBP1 -0.3988562463 2.493912e-01 0.5756644880
510 Q12907 LMAN2 -0.3156453918 1.074554e-01 0.2621010721
511 Q8NBK3 SUMF1 0.2109373270 5.845005e-01 -0.4603575127
512 P20645 M6PR -0.4647944846 3.844957e-02 0.4711022282
513 Q9UBU9 NXF1 -0.6411723992 1.886110e-02 0.5022800746
514 P32119 PRDX2 0.0766155588 7.966408e-01 0.3696025245
515 P61201 COPS2 -0.2718669436 1.040782e-01 0.2930714596
516 O75431 MTX2 0.0322426388 9.018516e-01 -0.3629461236
517 Q8IWA5 SLC44A2 0.5717115459 7.597003e-02 0.3109732814
518 P24844 MYL9 0.2870405810 2.959670e-01 -0.5627771670
519 O43488 AKR7A2 -0.1358950402 4.967546e-01 0.4110057430
520 P17252 PRKCA 0.4593747770 1.034073e-01 0.2962363732
521 Q08945 SSRP1 1.0802132673 1.029047e-08 0.3710919668
522 P55061 TMBIM6 -0.0717644373 6.847280e-01 0.4929378830
523 P07099 EPHX1 -1.9148323190 1.510118e-07 0.3221245491
524 P49756 RBM25 0.1755407515 2.902732e-01 -0.5368877021
525 Q92643 PIGK 0.7292956331 2.254813e-03 0.4288792875
526 Q9HAN9 NMNAT1 -0.2910727001 1.152230e-01 0.3991490568
527 O15144 ARPC2 -0.6100720629 2.066893e-05 0.3211464316
528 P62979 RPS27A 0.0395205375 8.730709e-01 -0.2239699579
529 Q13642 FHL1 1.0965471675 3.659715e-02 0.3805890001
530 O75083 WDR1 -0.3374692161 1.847864e-01 0.2340067894
531 Q13547 HDAC1 0.8040082602 3.445784e-05 -1.0167907744
532 Q15365 PCBP1 0.0993692416 6.057608e-01 -0.3061675928
533 O75569 PRKRA -0.5328514505 1.381915e-02 0.3809017814
534 Q7LBC6 KDM3B 1.0176730569 2.037186e-08 -0.9503690547
535 Q8NCA5 FAM98A 1.1007004384 6.895728e-08 -0.2770389541
536 Q6P1L8 MRPL14 -0.0188183573 9.463694e-01 -0.3469523732
537 Q9P289 STK26 -0.0773877778 7.551357e-01 0.4756052660
538 P05388 RPLP0 -0.1908294607 3.397934e-01 -0.2717749456
539 P47985 UQCRFS1 -0.0457454155 8.623682e-01 0.2737215840
540 O75477 ERLIN1 0.9890699467 4.421037e-03 0.9477072136
541 Q03518 TAP1 -3.1736455781 1.479107e-08 0.4421568992
542 P61160 ACTR2 -0.2940751330 2.985995e-01 0.3580260837
543 P47756 CAPZB 0.2739979063 1.202877e-01 0.2822669904
544 P31937 HIBADH 0.6887903854 9.639952e-04 0.3441131027
545 O60716 CTNND1 0.4035269561 3.311900e-01 -0.2304867318
546 Q9H0U6 MRPL18 -0.5507188132 9.301754e-05 -1.3334459844
547 P36969 GPX4 -0.1335553661 5.274344e-01 0.2666889930
548 Q8WY22 BRI3BP 0.8292030105 4.240227e-02 0.4902556476
549 Q9H6U8 ALG9 -0.3675387700 4.968232e-03 0.9940491999
550 P62937 PPIA -0.9008668330 2.162977e-06 0.2950316011
551 Q9NPC6 MYOZ2 0.9109674806 1.246893e-02 -0.5035953865
552 E9PAV3 NACA 0.2581178070 2.269935e-01 -0.4199626116
553 P24539 ATP5PB 0.4977984458 3.617286e-02 -0.4602042411
554 P08670 VIM -1.1785896409 3.597197e-05 0.2688944771
555 Q15274 QPRT 0.5395076738 5.065405e-02 0.2424456522
556 Q9NUL7 DDX28 -0.5469654820 1.973327e-03 -0.9091187813
557 Q14240 EIF4A2 0.3995775654 1.659073e-02 -0.3120783275
558 Q8N2Q7 NLGN1 1.8778072491 5.407303e-09 -0.7657686906
559 P46821 MAP1B -0.1636857451 5.696421e-01 0.3085520521
560 Q9NVA2 SEPTIN11 -0.5036513202 2.945199e-01 0.4225280356
561 P05413 FABP3 1.2309485446 3.634266e-04 0.2972655757
562 O76062 TM7SF2 -0.5559958215 6.128040e-03 0.2490267354
563 Q9ULD2 MTUS1 -0.7096277477 5.396461e-02 -0.7733423209
564 Q9BTV4 TMEM43 0.1545802524 6.906027e-01 0.4077539594
565 P22314 UBA1 0.0636136551 6.862526e-01 0.2742359818
566 P49189 ALDH9A1 0.3314445510 1.113250e-01 0.2844682295
567 Q8WYA6 CTNNBL1 0.2123630545 1.096362e-01 -0.4901126467
568 P63027 VAMP2 0.0998023599 6.710640e-01 -0.6054917542
569 O00267 SUPT5H -0.2086574583 1.889684e-01 -0.4883081268
570 Q8NBJ5 COLGALT1 0.1146598393 7.352198e-01 0.3474954001
571 O14841 OPLAH 0.8163379560 1.409651e-03 -0.4760189497
572 P17600 SYN1 -0.1656643340 7.339746e-01 0.5994787416
573 Q9UKK9 NUDT5 -0.2026747363 2.779936e-01 0.3541283421
574 Q86XL3 ANKLE2 -0.1916505126 4.429647e-01 1.3845804736
575 P05198 EIF2S1 0.0973122814 3.981279e-01 -0.3544038723
576 P51688 SGSH -0.1004932999 7.268621e-01 0.2929826523
577 Q86UL8 MAGI2 0.4296374072 1.322177e-01 0.3862327095
578 P00367 GLUD1 -0.2893886116 1.301154e-01 0.2670106787
579 Q96BJ3 AIDA 0.1917527460 4.898020e-01 0.6582557815
580 Q99575 POP1 0.0956093303 7.534672e-01 -0.6414286222
581 O43719 HTATSF1 0.4384987692 5.781667e-03 0.3884105367
582 Q86X76 NIT1 -0.2862856475 8.634769e-02 0.3856365267
583 O95210 STBD1 -0.5584720177 4.751430e-02 0.2866070079
584 P42356 PI4KA -0.2367648935 1.029220e-01 1.2271614838
585 O43678 NDUFA2 -0.4041656581 1.833207e-01 -0.5458101749
586 P23246 SFPQ 0.6611575762 2.564757e-03 -0.2168170966
587 P19784 CSNK2A2 -0.1355469726 3.194378e-01 0.7709444858
588 P17096 HMGA1 -0.2357947196 4.906365e-01 -0.5797074831
589 Q9UKM9 RALY -0.0483677000 7.785561e-01 -0.4627118864
590 Q9H6W3 RIOX1 0.1292883279 3.904879e-01 -0.5569526335
591 P55786 NPEPPS -0.5797105043 1.268447e-04 0.3432192302
592 Q07812 BAX -0.6413241147 2.582908e-02 0.4538761304
593 P22234 PAICS 1.6520499009 3.041109e-09 0.3942821645
594 Q9NZ43 USE1 0.3351504929 8.915003e-02 -0.4723754360
595 Q9H3P7 ACBD3 -0.5997582631 2.242583e-05 -0.3259712832
596 Q8NFW8 CMAS 0.2392759251 1.849662e-01 0.2913882873
597 P15170 GSPT1 0.0415525754 7.839481e-01 0.4042387632
598 Q5VYK3 ECPAS 0.0108414164 9.417671e-01 0.4792864217
599 Q9UII2 ATP5IF1 -0.3284880457 2.263708e-01 -0.5779054981
600 O43708 GSTZ1 -0.7799865069 1.831524e-05 -0.6957611001
601 O75607 NPM3 1.5239330544 5.414239e-06 -0.9024633221
602 Q53FA7 TP53I3 -1.3570560321 3.446817e-04 0.5307514644
603 Q9NPH2 ISYNA1 -1.3444834440 1.362227e-08 0.4510412715
604 P07741 APRT -0.3832130302 6.588620e-02 0.4023932468
605 Q14257 RCN2 0.6425795337 7.231870e-02 -0.8584705001
606 Q14157 UBAP2L 0.1914422774 3.604566e-01 -0.3441134306
607 Q24JP5 TMEM132A 0.2414741743 6.313552e-01 -1.4422446639
608 Q01518 CAP1 -0.5346497883 2.751801e-01 0.3829117241
609 P61962 DCAF7 -0.4815590890 3.404176e-04 -0.3313386279
610 O15460 P4HA2 -0.9766244719 1.487283e-03 -0.3027177373
611 Q99747 NAPG -0.4343916927 1.543643e-03 -0.3890434609
612 Q8TAE8 GADD45GIP1 0.3882491564 1.062931e-01 -1.2300854866
613 P43490 NAMPT -1.0194115561 6.849385e-04 0.5174534867
614 Q7L2E3 DHX30 0.0340490413 8.159683e-01 -0.2764088254
615 O75695 RP2 -1.1714405268 8.368133e-03 0.4557587058
616 Q53R41 FASTKD1 1.3223735741 3.743997e-04 -0.3721521378
617 Q6IBS0 TWF2 -0.1173084348 7.841181e-01 0.7200825532
618 O94832 MYO1D 0.2690337919 6.476079e-01 0.7113059870
619 Q9BYC8 MRPL32 -0.4480979361 2.429880e-02 -0.2881419915
620 P48643 CCT5 -0.0058820803 9.772284e-01 0.2426027202
621 O15372 EIF3H -0.2610659080 3.763684e-02 -0.3263963987
622 Q96AQ6 PBXIP1 -0.0163638588 9.621687e-01 0.3309292514
623 Q7L5N1 COPS6 -0.2350807816 9.640492e-02 0.3315156795
624 Q9NVR2 INTS10 0.0338200374 8.453607e-01 -0.8769919926
625 Q9UMX0 UBQLN1 0.2922786773 1.457348e-03 -0.2377988557
626 Q9NQ50 MRPL40 0.6286217574 3.878009e-03 -0.3913373827
627 Q14683 SMC1A 0.4311916987 8.116395e-02 -0.5756236294
628 Q14232 EIF2B1 -0.6603408853 8.111896e-09 1.9462616239
629 Q92604 LPGAT1 0.7704135697 5.514489e-07 1.0405755950
630 P08572 COL4A2 0.4491763899 1.258861e-01 -0.3643688597
631 P07384 CAPN1 -1.3219536649 6.187266e-07 0.2261268785
632 P52272 HNRNPM 0.2186810007 1.847864e-01 -0.2797465658
633 Q86W42 THOC6 -0.4215140472 6.582871e-02 -0.9444680116
634 P28347 TEAD1 -0.0286435805 8.816473e-01 -0.3519508310
635 P50461 CSRP3 0.2294442348 6.251060e-01 0.2553134985
636 P00390 GSR -0.5967623594 1.877845e-04 0.2636667900
637 P46777 RPL5 0.0831884957 6.476079e-01 -0.2495164254
638 P04181 OAT -0.0401454901 9.416420e-01 0.9716895965
639 Q96DU9 PABPC5 0.8939401998 6.783585e-04 0.6708709984
640 P35241 RDX -0.1606314650 3.331075e-01 0.2499929201
641 P31943 HNRNPH1 0.4866003602 3.866085e-03 0.2549349323
642 Q5VTL8 PRPF38B 0.1010820245 5.542266e-01 -0.4484439926
643 P07737 PFN1 0.1190329014 6.606078e-01 0.2594450203
644 Q6IQ23 PLEKHA7 0.8724483086 7.178181e-03 -0.3220582211
645 P28289 TMOD1 1.0742952939 2.057250e-02 -0.3767097442
646 Q9UBQ5 EIF3K -0.0067538517 9.802232e-01 -0.3198561727
647 O15431 SLC31A1 1.2095187333 1.510118e-07 0.8765074048
648 Q93052 LPP 1.3285364435 1.294344e-09 0.5077176987
649 Q15233 NONO 0.6393183642 2.593862e-08 -0.2203773267
650 B0YJ81 HACD1 0.8508394849 1.807684e-03 0.4263671815
651 P00441 SOD1 -0.4671522469 7.872033e-03 0.4394854663
652 Q01085 TIAL1 -0.0550344146 6.381128e-01 -0.3549740982
653 Q2V2M9 FHOD3 1.2501354304 1.815337e-05 -0.7493233584
654 P49674 CSNK1E -0.1962455236 5.504317e-01 -0.7750987888
655 Q9NWH7 SPATA6 0.3844624298 1.008895e-01 0.5727472293
656 Q8IXM3 MRPL41 0.6549381927 6.640458e-02 -0.3990313451
657 Q9NX58 LYAR 0.5242236978 6.336421e-02 -0.8605130413
658 P43304 GPD2 0.0926100540 7.999934e-01 0.3402365495
659 P05556 ITGB1 -0.0767833405 7.007477e-01 0.2519834655
660 Q8NBN3 TMEM87A 0.2225276227 3.289896e-01 -0.4900780058
661 Q96CT7 CCDC124 0.1104749174 5.125304e-01 -0.4060190842
662 Q969Z0 TBRG4 0.2053348669 1.958325e-01 0.2455943690
663 Q08380 LGALS3BP 0.8116587964 8.347575e-03 -0.2613356849
664 Q96T23 RSF1 -0.3474590463 1.893405e-02 -0.3131375395
665 Q9Y3B8 REXO2 -0.9568243220 3.426112e-06 -0.4786573745
666 Q92575 UBXN4 0.2809817986 9.823708e-03 -0.2357279698
667 P27144 AK4 -0.5534132180 3.175948e-01 -0.6088953174
668 Q9BUE6 ISCA1 0.0163704418 9.340454e-01 -0.5666584588
669 Q9NRZ5 AGPAT4 1.2574505904 4.846370e-07 -0.4871600338
670 Q8N8S7 ENAH 0.1605520564 4.794633e-01 -0.5071440857
671 Q9Y4E8 USP15 -0.6910215805 3.446377e-04 0.4269619270
672 P22695 UQCRC2 0.1706856323 3.959487e-01 0.2418092957
673 Q8ND56 LSM14A 0.3059021188 2.680936e-02 -0.3500765191
674 Q8N1F8 STK11IP -0.3656655059 5.497988e-03 -0.6479501264
675 A1L0T0 ILVBL 1.5030893035 3.659487e-09 -0.2521369710
676 Q9UN36 NDRG2 0.1470911810 6.569264e-01 -0.4168096232
677 Q9BQT8 SLC25A21 1.4846188142 5.402980e-06 0.2914019843
678 Q12824 SMARCB1 0.0348891813 8.905595e-01 -0.3203859112
679 O94905 ERLIN2 0.1035191096 4.586469e-01 0.2275121181
680 Q9NRG9 AAAS 0.6726711025 2.071350e-05 -0.3584746085
681 O60237 PPP1R12B 1.7489695447 3.631344e-04 -0.4003948098
682 O15533 TAPBP -0.0792272891 7.451698e-01 0.4751868334
683 P51608 MECP2 0.0697471352 6.652472e-01 0.4218689960
684 P61158 ACTR3 0.0769307747 8.048556e-01 0.3166017563
685 Q03001 DST 0.6671658276 1.485206e-04 -0.6141941812
686 Q9BVT8 TMUB1 0.1919158489 3.566117e-01 -0.5405761239
687 P55809 OXCT1 -0.2174422855 1.693419e-01 0.2434337963
688 Q99832 CCT7 -0.1183479718 2.591770e-01 0.2478731192
689 Q9Y619 SLC25A15 -1.3600982211 6.843738e-10 0.4805033783
690 O14910 LIN7A -0.0029448527 9.940050e-01 -0.3979042815
691 Q9P2D7 DNAH1 0.0317203002 9.247605e-01 -0.3617650877
692 P45974 USP5 0.4272082820 3.347588e-04 0.4780870272
693 Q9Y6R4 MAP3K4 0.1365172003 3.829033e-01 -0.3299816274
694 Q9BRA2 TXNDC17 0.0869574681 7.454704e-01 0.5433263672
695 P39748 FEN1 0.7419165260 3.358585e-02 0.5040722392
696 O43293 DAPK3 0.5693891008 5.910806e-02 -0.6285225768
697 Q9Y666 SLC12A7 0.6011450211 1.239458e-01 -0.4381618809
698 Q13243 SRSF5 -0.9385942458 2.054642e-08 -0.3170640659
699 O60783 MRPS14 -0.0066880886 9.775133e-01 -0.5086372728
700 P07919 UQCRH 0.1359094849 6.906027e-01 -0.5651417812
701 Q9NX63 CHCHD3 1.0427572607 2.935836e-04 -0.3277408282
702 P55084 HADHB -0.2677472580 1.547869e-01 0.2097034528
703 P13489 RNH1 -0.0706709931 6.871579e-01 0.4345200177
704 Q96DI7 SNRNP40 0.9869211353 2.164541e-09 -0.1970792390
705 Q7L2J0 MEPCE 0.2026658218 3.182126e-01 -0.5611017091
706 Q96BY9 SARAF -0.0647009289 7.866349e-01 0.4949614588
707 P35580 MYH10 0.1599521080 5.234833e-01 0.2579626136
708 Q702N8 XIRP1 0.6888344015 9.755848e-02 0.3451051635
709 Q9NZJ4 SACS -0.1521014978 6.314397e-01 0.2581561934
710 P10253 GAA -0.1872497079 3.260615e-01 0.2597096574
711 P13693 TPT1 -0.3736870386 1.059118e-01 0.3488953735
712 P25787 PSMA2 -0.3411146970 1.154110e-01 0.2237141090
713 Q15059 BRD3 -0.0642290127 7.380837e-01 0.7008214340
714 P62829 RPL23 -0.0375054703 8.722541e-01 -0.2495856064
715 P02751 FN1 0.4059860559 6.382477e-01 -0.6182199049
716 P23526 AHCY -0.4200199217 4.021328e-04 0.3846324108
717 Q14108 SCARB2 -0.5811844517 6.050463e-02 0.3501590830
718 Q92692 NECTIN2 0.3327029312 1.442756e-01 0.3587154090
719 Q13595 TRA2A 0.5837181309 1.118645e-05 -0.3544887951
720 Q14103 HNRNPD 0.6137841986 1.798761e-03 -0.2356367552
721 Q14687 GSE1 0.4615816199 2.834109e-02 0.3011342509
722 O00442 RTCA 0.0497484933 7.143912e-01 0.3236586076
723 P22392 NME2 0.6019933568 7.480706e-03 0.2216193309
724 P55145 MANF 0.5420947519 5.951120e-02 -0.4247296304
725 Q9BQA1 WDR77 -0.3514704546 3.562026e-03 1.0060757957
726 Q96T37 RBM15 -0.1629125831 5.332425e-01 -0.3326641434
727 P62312 LSM6 0.4407276866 5.295960e-02 -0.4824660783
728 P62341 SELENOT -0.0028886621 9.902110e-01 -0.3898158084
729 O43795 MYO1B -1.0346866233 1.283428e-04 0.3917883122
730 Q9NVH0 EXD2 1.1161067985 1.377560e-08 -0.6313561384
731 Q53S58 TMEM177 1.6642066794 3.698369e-06 -0.4765063730
732 Q8N2K0 ABHD12 -0.2813628352 5.984460e-03 0.4113335486
733 Q7Z478 DHX29 0.5915033898 8.893336e-07 -0.5521116291
734 P22059 OSBP 0.2496588428 7.648157e-02 -1.5819245055
735 O14929 HAT1 0.8951330995 2.332618e-03 0.7983739285
736 P40925 MDH1 0.5631077569 8.819686e-02 0.2955321084
737 Q15424 SAFB 0.0150735999 9.393487e-01 -0.2113807956
738 Q8IZD9 DOCK3 -1.9038208031 2.826730e-05 -0.4601150657
739 Q9Y2R5 MRPS17 0.4574472322 1.611673e-02 -0.2305341454
740 O15164 TRIM24 -0.4664298084 6.385852e-02 -0.3100285550
741 O15143 ARPC1B -0.2565048751 5.251166e-01 0.2949767775
742 Q9UJU6 DBNL -0.2499848751 6.816093e-02 0.5606788831
743 Q9NR31 SAR1A 0.2363214759 1.614588e-01 0.1959339329
744 P11047 LAMC1 -0.1406192194 5.612558e-01 0.2901354561
745 P08133 ANXA6 0.9749843576 9.887322e-12 0.3743442056
746 Q9NR50 EIF2B3 0.5703202424 5.512294e-05 0.4164645917
747 Q6P2E9 EDC4 0.4108529510 1.252629e-02 0.2671590393
748 P07947 YES1 -1.2189749153 6.403973e-06 0.8030695959
749 Q13867 BLMH 0.1776476793 3.490101e-01 0.3373069173
750 Q9NZN3 EHD3 0.2435280219 4.288570e-01 0.1925063729
751 Q16762 TST -1.4379139834 8.395059e-10 0.2678680274
752 Q14BN4 SLMAP 0.6937765036 9.737918e-02 -0.6357207592
753 P49914 MTHFS 0.5510523939 8.411946e-02 -0.3727031427
754 P17931 LGALS3 -2.5929374784 2.490015e-12 0.9625827295
755 Q86V15 CASZ1 0.8639407478 1.565329e-03 -0.6604771128
756 Q9Y678 COPG1 0.1067590686 5.701039e-01 0.2606506039
757 P61088 UBE2N -0.1635906008 2.465348e-01 0.4780619425
758 P30038 ALDH4A1 -0.0038355019 9.917878e-01 0.1953479302
759 P26885 FKBP2 0.1433370710 4.421703e-01 -0.5035273514
760 Q96CW5 TUBGCP3 1.0142092917 1.681253e-08 0.2827323465
761 Q96T51 RUFY1 0.4127955103 3.713102e-04 0.2433044713
762 P15289 ARSA -0.6910198170 4.722300e-04 0.3370065119
763 Q09028 RBBP4 -0.0508643970 6.176985e-01 -0.2283178102
764 Q9NWT8 AURKAIP1 0.0206912716 9.398638e-01 -0.9917786351
765 Q8IUX1 TMEM126B 0.2342691077 3.325270e-01 -0.3178565596
766 O95319 CELF2 0.5525093287 1.349687e-03 -0.2973479666
767 O14744 PRMT5 0.3402711208 2.329948e-03 0.5622037955
768 P54646 PRKAA2 0.4755630769 1.349687e-01 0.3472953318
769 P07858 CTSB -1.0268972427 5.304533e-07 0.2022527967
770 P33176 KIF5B 0.1552245851 3.577067e-01 0.2534894382
771 Q9UDY4 DNAJB4 -0.7021476742 3.459294e-03 0.2982075190
772 Q96EY1 DNAJA3 0.1113988217 5.546771e-01 -0.3118180617
773 Q8N4L2 PIP4P2 0.1266681155 6.125831e-01 -0.3896896872
774 P11177 PDHB 0.2567833368 1.582214e-01 0.2136331629
775 P17174 GOT1 0.8094163135 1.441070e-02 0.3350182125
776 Q8IVP5 FUNDC1 -0.0092819535 9.811352e-01 0.4600303072
777 O14773 TPP1 -0.1834997747 4.230061e-01 0.2517810618
778 P40227 CCT6A -0.2531332079 1.627520e-01 0.2546402387
779 P38606 ATP6V1A -0.5007412522 1.660687e-01 0.2052176420
780 O75208 COQ9 0.1017936983 6.244844e-01 -0.3265285959
781 Q9Y241 HIGD1A -0.1579891207 5.315324e-01 -0.2504555886
782 Q15019 SEPTIN2 -0.2199549265 1.267210e-01 0.3261869153
783 Q9Y2B0 CNPY2 -0.1076399004 7.320698e-01 -0.4768480877
784 Q5JSH3 WDR44 -0.2588684197 1.173070e-01 0.3483007813
785 Q8TB61 SLC35B2 0.7906029307 1.825629e-03 -0.4518085483
786 O94925 GLS -0.9953780835 1.405469e-05 0.2333756716
787 O94851 MICAL2 -0.2176904615 5.697835e-01 -0.3030187814
788 Q6P9B9 INTS5 -0.5362100362 4.876540e-04 -0.3672135897
789 P19237 TNNI1 0.5409715269 4.832926e-01 -0.5832965628
790 Q8NI60 COQ8A -0.9926464570 7.613501e-04 0.2684334443
791 O43175 PHGDH 0.6948338219 4.589757e-03 0.3128419382
792 Q9H082 RAB33B -1.2739844415 2.469365e-08 0.5793168823
793 Q00688 FKBP3 0.0120297357 9.664295e-01 0.3469715716
794 Q8N5K1 CISD2 0.7865389802 6.443198e-04 -0.2494762484
795 Q53GQ0 HSD17B12 -0.2050903596 4.474464e-01 0.2636347396
796 Q15119 PDK2 0.9203529177 5.124475e-04 -0.4245385559
797 Q8NFZ8 CADM4 0.4605378959 1.349615e-01 0.3074889502
798 O75937 DNAJC8 -0.5934749336 2.457478e-07 -0.8903072704
799 P52788 SMS 0.5028428846 4.421612e-02 0.7752797052
800 Q9Y2G8 DNAJC16 -0.0896233969 6.038524e-01 -0.3926432183
801 Q9Y617 PSAT1 -0.1757422936 6.817153e-01 0.6649855107
802 Q7Z7B0 FILIP1 1.4561039118 2.580053e-06 -0.2594882676
803 Q9BZH6 WDR11 -0.1604207703 3.122814e-01 0.3077656887
804 O15160 POLR1C -0.3304019405 9.457277e-02 -0.5328005416
805 Q15717 ELAVL1 -0.1791772256 1.634265e-01 -0.2644192279
806 Q86VR2 RETREG3 -0.7348944119 4.591830e-04 0.9144363126
807 Q92544 TM9SF4 0.2604999245 1.576993e-01 -0.2630598716
808 Q7L2H7 EIF3M 0.4417920457 1.341720e-02 -0.4165979428
809 Q9P202 WHRN -3.7907907294 5.296885e-18 -0.4396852898
810 Q14315 FLNC 0.0091980102 9.797195e-01 0.2407867819
811 O14579 COPE -0.1899210959 2.457766e-01 -0.4194876561
812 Q9BVC6 TMEM109 1.0778444594 1.278189e-07 0.2159356176
813 Q8NHP8 PLBD2 0.0427569679 8.842507e-01 0.2536745160
814 O95373 IPO7 -0.7179835937 4.379434e-05 0.2658177394
815 Q8NBN7 RDH13 0.5405853327 1.313719e-01 -0.3638958128
816 Q12849 GRSF1 -0.2797399863 2.235376e-02 -0.2447808690
817 O15294 OGT 0.2622533078 1.383752e-01 -0.3081091741
818 Q9Y639 NPTN 0.2451096282 2.439584e-01 0.2648427227
819 P07948 LYN -0.2187979779 3.709284e-01 0.2004440899
820 Q9HC07 TMEM165 -0.0768647081 8.169991e-01 -0.2575657257
821 Q86YM7 HOMER1 0.2049307776 6.395442e-01 -0.2236535786
822 Q9UBF2 COPG2 -0.2187991718 3.184513e-01 0.8256921260
823 Q8IXB1 DNAJC10 0.5575281221 9.531126e-03 0.2569521756
824 Q9UNL2 SSR3 0.8247432844 1.175747e-04 -0.4034222028
825 Q9P2E9 RRBP1 0.1485374403 7.794919e-01 -0.3297708482
826 P49790 NUP153 0.2273400159 1.240236e-01 -0.3131665674
827 O95674 CDS2 0.6041098732 1.248110e-02 0.6374003101
828 Q15459 SF3A1 0.0149075549 9.416420e-01 -0.2070695644
829 Q6ZUS5 CCDC121 -0.3088625409 2.057986e-01 -1.0874069922
830 Q9UGI8 TES -0.2718416723 3.820426e-01 0.2629903558
831 Q96KA5 CLPTM1L -0.3461131673 1.449524e-01 0.4813606706
832 Q5JRX3 PITRM1 -1.4530277020 2.719314e-08 0.2504261087
833 Q9Y6G9 DYNC1LI1 -0.1959136088 1.442756e-01 0.2240779488
834 O14936 CASK -0.8152996245 6.393939e-03 0.2772116486
835 Q9NTX5 ECHDC1 0.2091493103 9.763701e-02 0.3097828770
836 Q96RT6 CTAGE1 0.4989257122 6.211457e-02 0.2580294367
837 P29966 MARCKS -0.6166755034 2.937736e-01 -0.5430377812
838 P06576 ATP5F1B 0.3304109780 3.478027e-02 0.2189506192
839 Q8NFV4 ABHD11 0.3292054123 1.093639e-01 -0.3398481794
840 O95817 BAG3 -0.4577460200 7.042418e-03 -0.6677963911
841 Q9BXJ9 NAA15 0.6306292851 9.605473e-06 -0.3740103288
842 Q96MV1 TLCD4 0.3443623814 4.219153e-01 0.2623120849
843 Q9NR45 NANS 0.0351492231 8.996647e-01 0.3146913223
844 P63241 EIF5A 0.3063341986 1.163757e-01 0.2769532214
845 Q8N766 EMC1 -0.0148415365 9.703914e-01 0.2279321175
846 Q9UHX1 PUF60 0.1308349073 3.871955e-01 -0.2098946096
847 Q14739 LBR 1.3656942419 2.574362e-06 0.2734819331
848 Q9BVS5 TRMT61B 0.1689631584 2.887540e-01 -0.4735072436
849 P22570 FDXR -3.0490137809 6.494646e-15 0.3135655531
850 Q6JQN1 ACAD10 0.4163115983 9.914669e-02 0.2456100233
851 Q12792 TWF1 0.1212247041 7.804761e-01 -0.5774892398
852 O60762 DPM1 -0.3015365935 8.012789e-02 -0.2377234491
853 Q96IP4 TENT5A -1.2399342896 5.565489e-08 1.1728031062
854 O15230 LAMA5 0.4447570795 1.072857e-01 -0.5469555280
855 P31323 PRKAR2B 1.2817323071 1.231591e-03 0.3632298261
856 Q9NRW7 VPS45 0.6171724986 1.884764e-04 0.2653227724
857 O76094 SRP72 0.4813531766 2.927449e-02 -0.2458223900
858 Q9NX14 NDUFB11 0.2929721988 2.570118e-01 -0.2311935849
859 Q8NF91 SYNE1 0.0363200034 9.112240e-01 -0.4360386458
860 O75915 ARL6IP5 -0.0069882044 9.721511e-01 0.2602322904
861 Q9Y6N1 COX11 -0.3963814121 1.567336e-03 0.8089524574
862 Q9NX61 TMEM161A 0.6897117325 1.251528e-04 -0.5679989932
863 P53992 SEC24C -0.0527575479 7.224271e-01 -1.1668691275
864 Q14019 COTL1 -0.3691141983 6.429733e-01 0.6632140707
865 Q9NPD3 EXOSC4 -0.4595099214 4.728026e-03 -0.4989232971
866 Q8IWB9 TEX2 0.3794846960 2.614909e-02 -0.2596002743
867 P35080 PFN2 0.5231094827 1.094566e-02 0.4131442460
868 Q9BX46 RBM24 0.2943106489 3.352250e-01 -0.3530349822
869 P11233 RALA -0.4600139862 2.007882e-03 0.2179385173
870 Q9P2W9 STX18 0.0238119456 8.787580e-01 -0.2484726219
871 Q8N3E9 PLCD3 -0.1796994289 3.699624e-01 0.2207670998
872 P05165 PCCA 1.0108453414 2.818499e-07 0.1902944993
873 P47755 CAPZA2 0.1417976794 6.301749e-01 0.2758038835
874 P39060 COL18A1 0.4101545222 1.816848e-02 -0.3024581704
875 O60306 AQR 0.1084464144 5.727434e-01 -0.6041590902
876 Q9H4M9 EHD1 -0.9635804815 3.086698e-07 0.1800152817
877 Q7RTP6 MICAL3 0.2015549206 5.110727e-01 -0.2343073623
878 Q9Y262 EIF3L -0.0130205025 9.403779e-01 -0.2814381562
879 Q96J84 KIRREL1 0.6724886606 1.291765e-01 0.6706125423
880 O14925 TIMM23 0.1195718542 2.140039e-01 -0.2276745311
881 Q8IYI6 EXOC8 -0.4093023401 1.707838e-03 0.6349943165
882 P50993 ATP1A2 1.4675780543 1.988062e-02 -0.2577987166
883 O14653 GOSR2 -0.1260510994 2.596516e-01 -0.3243496360
884 P25705 ATP5F1A 0.4306473723 1.132568e-02 0.2257005707
885 Q8IWB7 WDFY1 -0.7829870674 8.936408e-03 0.7064385530
886 Q9BS92 NIPSNAP3B -0.1324233067 6.953143e-01 0.2694926792
887 Q15404 RSU1 0.8263313732 2.441850e-04 -0.5275078037
888 O00422 SAP18 -0.8366488364 8.327475e-05 -0.2535599295
889 Q7Z3B4 NUP54 0.1466943110 5.563617e-01 1.8506747811
890 Q9P2J5 LARS1 0.5978709437 1.600134e-07 0.2285428331
891 P62495 ETF1 -0.3965590239 1.851360e-03 0.3631770352
892 P26038 MSN 0.4133762823 2.478151e-01 0.1709112499
893 P30041 PRDX6 -0.8741911770 9.707431e-07 0.2881943921
894 Q9Y2D4 EXOC6B -0.0919038948 6.236365e-01 0.6507001381
895 Q8N465 D2HGDH 0.0259624405 9.062350e-01 0.2672801369
896 Q92688 ANP32B 0.4804698795 8.123762e-03 0.3991123511
897 Q6STE5 SMARCD3 0.8576798083 1.141002e-05 -0.2675357203
898 O95881 TXNDC12 0.4742654502 8.991521e-03 -0.3698129169
899 Q9Y2Q9 MRPS28 0.5024745440 6.207591e-02 -0.9935453361
900 Q14203 DCTN1 0.2309867566 8.641046e-02 0.2375835105
901 O15382 BCAT2 0.4597613267 4.616915e-04 0.2498531004
902 P53041 PPP5C 0.9762585878 2.639922e-12 0.3091713831
903 O94874 UFL1 0.8424211554 1.200925e-06 -0.2854740636
904 Q96K17 BTF3L4 -0.0694849844 6.937699e-01 -0.6777132062
905 Q96RT1 ERBIN -0.1093053646 4.506383e-01 -0.3295656488
906 Q16795 NDUFA9 0.7323482247 3.964602e-05 0.1927761825
907 Q92599 SEPTIN8 0.5157063915 1.160454e-02 0.2024064979
908 P51398 DAP3 0.9266599244 1.774996e-07 -0.2499363600
909 Q5T4S7 UBR4 0.2486941173 2.676098e-01 0.5108829847
910 Q15417 CNN3 -0.7253456121 4.411046e-03 0.4565561668
911 Q8WUM4 PDCD6IP -0.5149553377 2.683067e-05 0.4075451648
912 Q9BYC9 MRPL20 0.1903756584 2.196497e-01 -0.5383363165
913 P58335 ANTXR2 0.1195977762 5.422546e-01 0.5629312410
914 Q15046 KARS1 0.1606257612 1.723397e-01 0.2374029245
915 Q03135 CAV1 -0.9300855868 7.400782e-02 0.1995018439
916 P04083 ANXA1 -0.0461632255 9.631503e-01 0.3359523597
917 Q15006 EMC2 0.6095726321 1.922097e-03 -0.3710452243
918 Q14517 FAT1 -0.8459858648 2.906147e-02 -0.9700068016
919 P0DP25 CALM3 0.3042375830 6.089589e-02 -0.5683668420
920 A2RRP1 NBAS 0.6358297250 1.124990e-04 -0.3033480951
921 P49321 NASP 0.0313830414 9.208014e-01 0.3808527490
922 Q14112 NID2 0.6089685079 1.261899e-01 -0.7753149080
923 P99999 CYCS 0.0493396030 8.807324e-01 -0.2130178742
924 P13929 ENO3 0.6449258844 1.389299e-01 0.3775704797
925 Q9HBU9 POPDC2 1.5945344204 2.724736e-03 -0.1759774239
926 P13798 APEH 0.2795448974 1.995638e-02 0.2389391661
927 Q92896 GLG1 0.0038275416 9.898522e-01 -0.2389296568
928 Q8N9F7 GDPD1 1.0732167208 8.957472e-04 -0.3218915392
929 O14950 MYL12B -0.6752782282 3.702169e-03 -0.4581729650
930 Q07157 TJP1 0.2930951888 6.588620e-02 -0.1907873045
931 Q9NV70 EXOC1 -0.2665690554 5.567732e-02 0.3095148387
932 P23786 CPT2 -1.1480949718 8.048024e-10 0.2091800381
933 Q9H000 MKRN2 0.3287332771 3.432010e-02 -0.7303962642
934 Q330K2 NDUFAF6 -0.8849238742 2.421835e-06 -0.6975382642
935 P17568 NDUFB7 0.3570215949 3.132859e-01 -0.4652801960
936 Q12905 ILF2 0.0387615287 8.313867e-01 -0.1636565050
937 Q00325 SLC25A3 0.6990663237 9.659669e-05 0.2434013775
938 P50990 CCT8 -0.1151594169 5.083174e-01 0.2098631154
939 Q9UKF6 CPSF3 -0.5498634751 6.118418e-06 0.5202758716
940 Q9H8M1 COQ10B 0.0040928588 9.850060e-01 -0.4021494489
941 Q08431 MFGE8 -0.7693245664 4.736294e-05 0.3344022603
942 Q8N4T8 CBR4 -0.7289628455 4.513419e-06 0.1957529169
943 Q9H553 ALG2 -0.2861101188 8.623609e-02 0.2221531721
944 Q13523 PRPF4B 0.0835591922 6.686509e-01 -0.3213637053
945 Q96A23 CPNE4 0.4401121522 5.161763e-01 0.3283358372
946 Q9Y6A4 CFAP20 0.2975429444 2.924956e-02 -0.2432424196
947 Q99460 PSMD1 -0.0400776179 7.032391e-01 0.1755410750
948 O94903 PLPBP 0.0284779230 8.799214e-01 0.3035410868
949 O00139 KIF2A 0.0099644132 9.620962e-01 0.5817846082
950 P14927 UQCRB 0.0231759786 9.531766e-01 -0.3014341275
951 Q9UMS4 PRPF19 0.0397906442 8.634162e-01 -0.2416057330
952 P28072 PSMB6 -0.2977006176 1.737828e-02 0.1629178650
953 O94760 DDAH1 -1.2222651325 6.451953e-04 0.6363531350
954 P51572 BCAP31 -0.5535838131 3.579409e-03 0.2609031879
955 O43155 FLRT2 -0.6565364545 4.780275e-02 -0.4750531410
956 Q01449 MYL7 0.5336212558 1.283220e-01 -0.4080785114
957 Q13617 CUL2 -0.0594813383 6.476079e-01 0.2439321263
958 Q2PPJ7 RALGAPA2 0.6569275809 5.158838e-03 0.5746045275
959 O14880 MGST3 0.3067880393 4.060940e-01 0.2074988516
960 Q6P6C2 ALKBH5 -0.1189052691 7.091700e-01 -0.5049489697
961 P55209 NAP1L1 -0.6201325860 2.092402e-04 0.2863524381
962 P55036 PSMD4 -0.0964899280 3.805719e-01 0.1776812272
963 Q9HD33 MRPL47 0.2554762149 2.760215e-01 -0.3659727073
964 Q96DZ1 ERLEC1 0.1565713350 4.134580e-01 0.4692238398
965 Q96RF0 SNX18 -0.8066293130 4.146307e-03 -0.9094283446
966 Q8WWA1 TMEM40 -0.5402682566 1.535104e-01 -0.7748569766
967 O75131 CPNE3 0.0006017617 9.978874e-01 0.2697861351
968 O15273 TCAP 2.2881799287 2.927843e-02 0.3182510946
969 Q9Y2K3 MYH15 -0.7504523419 2.827785e-01 -0.5962386272
970 Q13148 TARDBP -0.2767561140 7.834289e-02 -0.2052262160
971 Q6ZRY4 RBPMS2 -0.4218662355 1.668584e-01 -0.5207844372
972 Q15287 RNPS1 -0.2382835791 8.198952e-02 -0.3093679118
973 O95822 MLYCD -0.1976594742 5.064806e-01 0.2195562657
974 O75534 CSDE1 -0.0653691148 6.954938e-01 -0.3217653128
975 Q9BSH4 TACO1 0.1071798699 7.162095e-01 -0.2463987244
976 Q9Y295 DRG1 0.4343534097 3.144624e-03 -0.2042030230
977 Q8IWA4 MFN1 0.0355707901 8.638571e-01 0.3031254880
978 Q9UJ68 MSRA 0.0690531004 6.398019e-01 0.4520051600
979 O75438 NDUFB1 -0.1909603695 6.244175e-01 -0.4073721122
980 P48059 LIMS1 -1.1820329846 9.547417e-05 0.2845010920
981 O14521 SDHD 0.5553709774 1.676135e-02 0.6828707650
982 Q8IWX8 CHERP 0.1666658517 3.685543e-01 -0.2741827603
983 Q00013 MPP1 1.9427738598 2.286116e-14 0.2673576413
984 P07602 PSAP -0.1813243140 3.301339e-01 0.2996491858
985 P02768 ALB -0.1259893048 9.682887e-01 0.1813038996
986 Q5HYI8 RABL3 -0.0018235256 9.932990e-01 0.6096474811
987 P09110 ACAA1 0.0249357682 8.965306e-01 0.2525502788
988 Q2TAL5 SMTNL2 0.1467268953 8.101386e-01 -0.4179533925
989 Q9Y6Q9 NCOA3 -1.0777882364 5.852037e-03 0.3992454030
990 Q96DV4 MRPL38 -0.2212564061 1.553935e-01 -0.2845310764
991 O43670 ZNF207 0.1018045171 3.918009e-01 -0.9218539849
992 Q9P2B2 PTGFRN 0.7660902561 1.138043e-02 0.2236670180
993 Q9UKV3 ACIN1 0.3329212994 1.650592e-02 -0.2256838069
994 Q92665 MRPS31 0.3901754512 6.832485e-02 -0.2616878415
995 P61923 COPZ1 0.0766732085 5.611689e-01 -0.2853890358
996 P08559 PDHA1 0.1750477058 4.419413e-01 0.1983900169
997 Q7Z4W1 DCXR -0.8704833695 8.965092e-04 0.3260169770
998 Q93008 USP9X -0.3162855346 3.867037e-01 -0.4530244840
999 P57740 NUP107 0.3496003321 1.794755e-01 -0.3587798251
1000 Q8TB22 SPATA20 0.3148845355 2.051312e-01 0.1798405753
1001 Q15369 ELOC -0.6869531304 2.099688e-06 -0.2699784691
1002 Q9GZT3 SLIRP 0.1659760476 5.798608e-01 -0.2760344148
1003 Q9NX00 TMEM160 0.0612060409 7.969343e-01 0.4628996523
1004 O14494 PLPP1 -0.1518940764 6.540261e-01 -0.5747954452
1005 O15355 PPM1G -0.4927385661 1.466417e-03 0.8194855442
1006 Q9NQR4 NIT2 0.2387231413 1.813028e-01 0.2024662845
1007 P49750 YLPM1 0.3700886974 9.752070e-02 -0.2510595044
1008 Q9UBQ0 VPS29 0.2536104755 2.329681e-01 0.2006268126
1009 Q9ULQ0 STRIP2 -0.0883828464 6.892018e-01 0.2366328761
1010 Q5JTH9 RRP12 -0.5708116705 1.032103e-01 -0.2766978235
1011 P62826 RAN 0.6027384305 6.088563e-04 0.2216165615
1012 P55287 CDH11 0.2882049217 6.821621e-01 -0.7330076615
1013 Q5VU97 CACHD1 1.0177770023 2.709308e-06 -0.2798743420
1014 Q15363 TMED2 -0.0233466988 9.207356e-01 0.2339965755
1015 P56556 NDUFA6 0.5684564686 9.153004e-02 -0.1926233296
1016 P63096 GNAI1 -1.4218247399 6.830061e-11 0.3335997898
1017 O95302 FKBP9 -0.0463607365 8.461508e-01 0.2443602043
1018 A6NJ78 METTL15 0.7550515034 1.614602e-05 -0.4571510920
1019 Q9NRK6 ABCB10 0.5652114841 5.019931e-03 0.2190583824
1020 O14907 TAX1BP3 -1.4210392542 8.264307e-08 -0.3224757532
1021 Q9UKM7 MAN1B1 0.1752593770 6.193836e-01 -0.5574282159
1022 Q9UBP4 DKK3 -0.2319026104 2.605354e-01 0.6821042386
1023 P12259 F5 -1.2386880915 3.470117e-01 0.4073259675
1024 P00387 CYB5R3 0.0165754913 9.488212e-01 0.1694320838
1025 Q9H4G0 EPB41L1 -0.5669181959 7.434396e-03 0.3791705016
1026 P35475 IDUA 0.0329431435 9.156707e-01 0.4743598857
1027 P31942 HNRNPH3 0.0463689881 7.599386e-01 -0.6346268799
1028 P50395 GDI2 0.1680521407 1.594557e-01 0.2610576155
1029 O95168 NDUFB4 0.7850763904 2.159324e-03 -0.6440503004
1030 P07951 TPM2 0.0670765094 8.011362e-01 -0.6021338456
1031 P40939 HADHA -0.0439308007 7.533651e-01 0.1851041865
1032 Q96EE3 SEH1L 0.0478673574 7.581510e-01 0.4602912846
1033 Q16540 MRPL23 0.3033165534 2.267761e-01 -0.4441561464
1034 Q9Y2T2 AP3M1 0.6553017315 9.730282e-09 0.1684261992
1035 P40926 MDH2 -0.1236527959 4.502836e-01 0.2223211902
1036 Q9NS69 TOMM22 0.0087281260 9.484325e-01 0.3003760482
1037 P04156 PRNP -1.1410070974 1.808163e-06 0.2250199589
1038 Q92734 TFG 0.2145229437 8.071085e-02 0.2279689200
1039 Q969P6 TOP1MT -0.4056391210 4.035648e-01 0.8647687743
1040 P52943 CRIP2 1.0385478432 3.655249e-03 0.2739689260
1041 Q15124 PGM5 1.2411532464 1.554380e-04 0.2773011733
1042 Q9BSR8 YIPF4 -0.1859739698 3.744347e-01 -0.3012102796
1043 Q8WTT2 NOC3L 0.5412351347 1.358450e-02 -0.5317944608
1044 Q9BW60 ELOVL1 -0.1864125831 7.101723e-01 -0.4149351657
1045 P39687 ANP32A 0.8494308005 4.364201e-07 -0.9428756110
1046 P49757 NUMB -0.6263374138 4.012865e-07 0.7438829815
1047 P10768 ESD 0.6282585286 1.332894e-02 0.5347772205
1048 P98160 HSPG2 0.0249069355 9.418177e-01 -0.2947119636
1049 Q9ULE0 WWC3 -0.3287921351 5.397758e-02 0.3052709232
1050 P06756 ITGAV -0.0036628192 9.901463e-01 0.1883455390
1051 Q9UKX3 MYH13 2.6319240265 4.927442e-06 0.3484502872
1052 P13639 EEF2 -0.1466171035 2.744447e-01 0.2163254542
1053 Q969Q5 RAB24 -0.4136407272 5.400707e-03 0.3537539950
1054 Q9Y230 RUVBL2 0.1924869830 1.374833e-01 -0.2118808800
1055 Q6P2Q9 PRPF8 0.0199878345 9.227264e-01 -0.1645047624
1056 Q4G0N4 NADK2 -1.2451834616 5.944150e-10 0.3179150726
1057 P28161 GSTM2 0.3494152399 1.217532e-01 -1.0126528211
1058 Q99470 SDF2 -0.3121417375 7.928556e-02 0.2742877121
1059 P05141 SLC25A5 0.0323084281 9.470804e-01 0.1752388592
1060 P53582 METAP1 0.6066468278 7.599310e-04 -0.3068330790
1061 Q8TAD4 SLC30A5 0.7591393290 3.805658e-06 -0.3732777871
1062 P55060 CSE1L 0.2378893508 2.990434e-01 0.4091759109
1063 O15091 PRORP 0.8154014564 2.908861e-07 -0.2562552421
1064 P62873 GNB1 0.2528335485 2.274096e-01 -0.1777631605
1065 P04406 GAPDH 0.1275573809 7.411443e-01 0.2606249142
1066 Q8TC12 RDH11 0.8626611190 7.887052e-07 0.1652025327
1067 P49327 FASN -0.5962963684 5.396461e-02 0.4285017684
1068 P37268 FDFT1 -0.4778184988 6.654641e-03 0.4290734589
1069 Q96L91 EP400 0.2009817341 2.146727e-01 -0.4746403647
1070 P14618 PKM -0.4858103234 6.241861e-02 0.3185482785
1071 O43390 HNRNPR 0.5315895314 1.982246e-04 -0.1484957651
1072 Q13428 TCOF1 0.8468016143 1.085352e-06 -0.2276177324
1073 Q96A65 EXOC4 0.6058767415 5.968732e-05 0.3332367779
1074 Q14344 GNA13 -0.8495024713 1.904966e-08 -0.4145648161
1075 Q9BSH5 HDHD3 0.1458391930 7.273371e-01 -0.3785623189
1076 Q02790 FKBP4 -0.4219765300 2.970464e-02 0.2517632624
1077 P12532 CKMT1B 0.3189274908 4.609424e-01 0.3851066822
1078 P12532 CKMT1A -0.0184073314 9.706144e-01 0.3851066822
1079 O95747 OXSR1 -0.6930139820 1.682823e-05 -0.2969421867
1080 Q8WWC4 MAIP1 0.4513648139 1.399208e-02 -0.1604667632
1081 Q0ZGT2 NEXN 1.5557338253 5.934942e-06 -0.1712369163
1082 Q8WXF1 PSPC1 -0.1595771459 3.171161e-01 -0.2346862373
1083 P02649 APOE 0.4604001113 2.870514e-01 -0.4349334489
1084 O75439 PMPCB 0.2744611640 3.556375e-02 0.2474615548
1085 P11766 ADH5 0.6237013071 3.521814e-03 0.3431203127
1086 P52926 HMGA2 0.3196203987 5.375888e-01 -0.4825620433
1087 Q12904 AIMP1 0.0468284387 8.099196e-01 0.1472376419
1088 Q96CM8 ACSF2 0.5162424633 3.982095e-02 0.2109320371
1089 P60228 EIF3E 0.3908875813 5.770630e-02 -0.1934319770
1090 Q56VL3 OCIAD2 -0.3691745379 3.140993e-01 -1.1556235158
1091 P54803 GALC -0.3742303001 1.625391e-01 0.4053021635
1092 Q8NDX6 ZNF740 -0.3816940537 1.117693e-02 0.6161897468
1093 O60725 ICMT 0.1083662631 4.429647e-01 -0.4737800938
1094 Q6ZMG9 CERS6 0.6201730241 2.096873e-03 -0.4165891174
1095 Q9BWU0 SLC4A1AP -0.1415998358 2.117596e-01 -0.4005840378
1096 Q86VX9 MON1A 0.4727584757 5.124475e-04 -0.4942796745
1097 Q96EK5 KIFBP 0.9888310990 5.708229e-09 -0.4534656876
1098 P27348 YWHAQ 0.0515756392 7.512007e-01 -0.6274318586
1099 Q02952 AKAP12 -1.4315524123 2.048071e-03 -0.3310385676
1100 Q99720 SIGMAR1 0.4357987381 6.202618e-03 -0.1955697004
1101 P60660 MYL6 -0.1045768329 7.385530e-01 -0.3794384882
1102 Q969G3 SMARCE1 0.4652326113 5.866240e-04 -0.3907690326
1103 P25325 MPST 1.0954059223 3.036855e-09 0.3486364653
1104 Q9BYT8 NLN 0.2114194894 5.360158e-01 0.2497676276
1105 P54289 CACNA2D1 -0.0815651133 7.198256e-01 0.2886669420
1106 Q8WZ82 OVCA2 -0.4018782433 1.327398e-01 -0.1856533008
1107 P42574 CASP3 -1.6038011779 2.933546e-09 0.5822243824
1108 Q92558 WASF1 -1.0036354192 4.535845e-07 0.2895967574
1109 Q8NBX0 SCCPDH 0.6776929220 4.818857e-06 0.1643488603
1110 P13804 ETFA -0.2818442738 1.411864e-01 0.1860273983
1111 Q13643 FHL3 -1.0466605470 5.960147e-04 0.1756591781
1112 Q8WVC6 DCAKD -0.5719796571 2.568020e-02 0.1748852996
1113 Q9BSJ8 ESYT1 -0.6367166593 4.096170e-02 0.1886056449
1114 P55196 AFDN 0.2091178559 1.298005e-01 -0.2564127074
1115 O14807 MRAS 0.1120639937 6.429733e-01 0.4264170297
1116 Q8NBL1 POGLUT1 -0.6596242310 1.587475e-02 -0.3876724743
1117 P31150 GDI1 0.1686184919 2.946914e-01 0.6114273746
1118 O14529 CUX2 1.0336963276 6.178952e-02 0.4127866418
1119 Q15286 RAB35 -0.2780641932 1.109953e-01 -0.1915257928
1120 Q8NEY1 NAV1 1.9662442223 3.747903e-08 -0.4378139709
1121 Q8N3C0 ASCC3 -0.6486076404 8.401111e-03 -0.5238838638
1122 Q16595 FXN 0.6398030501 9.726706e-04 -0.3371877748
1123 Q9NWS8 RMND1 0.2602737035 6.081843e-02 0.2420462084
1124 Q9BY67 CADM1 -0.4034661933 1.815525e-01 0.2844115419
1125 P29279 CCN2 0.3821801087 6.180574e-01 -0.8798236579
1126 Q05048 CSTF1 0.2951151024 2.640275e-02 0.1715145274
1127 Q99497 PARK7 0.0583411647 7.139775e-01 0.2191932166
1128 P62258 YWHAE 0.3142248906 2.818680e-03 -0.4324579082
1129 P61224 RAP1B -1.5013856554 1.311531e-05 -0.3147737961
1130 Q16543 CDC37 -0.5108490580 1.215245e-05 0.8527218013
1131 Q01082 SPTBN1 -0.0048328352 9.875678e-01 0.1512178834
1132 Q96T76 MMS19 -0.5602189701 7.363503e-05 0.4412916923
1133 P12268 IMPDH2 0.2390327046 1.472817e-01 -0.2698557914
1134 O43766 LIAS 0.6649578996 6.135567e-03 -1.1289560057
1135 P54136 RARS1 -0.4148859560 9.917262e-03 0.1495354361
1136 P14314 PRKCSH 0.0562381883 8.270659e-01 0.2016706204
1137 P48728 AMT 0.6051898352 4.147509e-02 0.2171183611
1138 Q96CM3 RPUSD4 0.2274541467 4.557228e-02 -0.3544502906
1139 P52756 RBM5 -0.1546649647 4.624358e-01 -0.8464717098
1140 P78344 EIF4G2 -0.4697120711 5.914711e-04 0.2593451257
1141 Q96GK7 FAHD2A -0.0165881490 9.235759e-01 0.2791955975
1142 Q8IUR7 ARMC8 0.4878246776 3.386954e-04 0.2030229675
1143 O75190 DNAJB6 0.4856672435 2.079892e-03 -0.2459882156
1144 Q16181 SEPTIN7 0.2802200640 1.432851e-01 0.2438979297
1145 O00429 DNM1L 0.6162961656 1.113388e-07 0.1755736706
1146 Q5T9L3 WLS 0.0530897999 8.330211e-01 -0.3865169903
1147 P49916 LIG3 0.4922429801 1.582479e-04 0.1707692990
1148 O43818 RRP9 -0.3284797629 5.104956e-02 0.5894990859
1149 P30085 CMPK1 -0.2729015270 2.130730e-01 -0.1933908597
1150 Q8NBS9 TXNDC5 0.4876545122 3.085543e-01 0.2019894057
1151 O15121 DEGS1 0.7115466365 1.713023e-03 -0.4371204792
1152 Q6ZV73 FGD6 0.2367997872 1.673359e-01 0.2874082823
1153 Q9GZR7 DDX24 -0.4542717013 2.459383e-02 -0.3096223957
1154 Q9UKN8 GTF3C4 -0.3939530826 7.672568e-02 -0.6266017327
1155 P51151 RAB9A 0.1237132687 6.844126e-01 -0.5759567126
1156 Q5VWP3 MLIP 1.4082377847 7.629580e-04 -0.1938196858
1157 P51665 PSMD7 -0.0126233128 9.413936e-01 0.1505964723
1158 Q9C0H9 SRCIN1 -0.3524688080 4.091536e-01 0.2171637939
1159 Q04917 YWHAH 0.2689926137 9.321517e-02 -0.4586416160
1160 Q7Z7N9 TMEM179B -0.7344085789 1.156193e-04 0.6261185914
1161 Q5UCC4 EMC10 0.2168141134 1.543301e-01 0.2690058380
1162 L0R6Q1 SLC35A4 0.8696231556 1.008397e-06 0.7132840229
1163 Q6UXN9 WDR82 0.0767347774 5.205339e-01 -0.3073078218
1164 Q8TCZ2 CD99L2 -0.0878460353 5.362211e-01 -0.3654760179
1165 Q5SYB0 FRMPD1 1.9818177950 2.144046e-04 0.4304354667
1166 P18206 VCL -0.0116573432 9.620962e-01 0.1625168061
1167 Q96MF6 COQ10A 0.1370566562 7.792366e-01 -0.5899767781
1168 O43290 SART1 -0.0824654706 5.621323e-01 -0.2948589306
1169 Q9NUQ7 UFSP2 0.4863813235 4.128438e-03 -0.4890693930
1170 P63167 DYNLL1 -0.5080263356 4.269633e-04 -0.4776309632
1171 Q99519 NEU1 -0.8060382687 1.349653e-04 0.2340729081
1172 Q9UKX7 NUP50 0.3178479574 8.032711e-02 0.4563067949
1173 Q9UBQ7 GRHPR 0.2494752880 3.913320e-01 0.1623730725
1174 Q8N4V1 MMGT1 0.2107773991 1.970990e-01 -0.3831556700
1175 P07954 FH 0.2011052174 3.531808e-01 0.1758702593
1176 Q8N163 CCAR2 -0.5003892785 1.148994e-03 -0.2234923015
1177 Q12800 TFCP2 0.3945259094 1.125052e-01 -0.8942465762
1178 P11216 PYGB 0.3706804227 2.218133e-01 0.2592249446
1179 P09493 TPM1 1.2522744866 4.075438e-04 -0.5195783053
1180 Q8IVF4 DNAH10 -0.9839650884 1.487763e-03 -0.6988988483
1181 Q5SVZ6 ZMYM1 1.4001510972 1.082586e-10 0.5097142713
1182 P18085 ARF4 -0.6154930300 1.344725e-02 0.2406756720
1183 Q8IZ52 CHPF -0.1520880634 4.751689e-01 0.6396365429
1184 P19525 EIF2AK2 0.1609265130 5.373424e-01 0.3289154011
1185 P37837 TALDO1 0.5147243339 7.599499e-05 0.3275565224
1186 P41252 IARS1 0.2027621499 1.155138e-01 0.3010367691
1187 Q9Y697 NFS1 0.4748574691 2.356207e-03 0.2601530251
1188 Q6IQ26 DENND5A 0.3579760163 5.329381e-02 0.2819111601
1189 Q96CU9 FOXRED1 0.7669916720 3.126725e-03 0.1623620999
1190 Q8TDX7 NEK7 0.0397505828 9.218093e-01 0.2370851894
1191 O75390 CS 1.1967109946 1.105975e-08 0.2019558931
1192 Q99798 ACO2 0.3624162228 3.742887e-02 0.1737075649
1193 Q9H987 SYNPO2L 0.4677785726 1.764840e-01 -0.2173125110
1194 Q8WUA4 GTF3C2 0.1565539482 3.922664e-01 0.2645293192
1195 P15927 RPA2 0.6335135818 3.158478e-04 0.5900679915
1196 Q15413 RYR3 0.3365342196 5.161763e-01 0.4907422965
1197 P61081 UBE2M -0.0260307838 9.041815e-01 0.3808241832
1198 Q5BJF2 TMEM97 0.1622419885 5.904522e-01 0.4124106934
1199 Q96CS3 FAF2 -0.1597987456 3.988428e-01 0.2017451620
1200 P78362 SRPK2 -0.4640259359 2.829528e-04 -0.3561675508
1201 Q9NS86 LANCL2 -0.2007028884 3.025541e-01 0.5336491286
1202 Q9BQ69 MACROD1 0.2563418328 6.744580e-01 -0.3061545662
1203 Q96N66 MBOAT7 -0.6330062537 1.683402e-02 0.2051623271
1204 Q13409 DYNC1I2 -0.4299918990 1.980653e-03 0.2249566098
1205 P47813 EIF1AX -0.0412253155 8.756696e-01 -0.5763856120
1206 P62995 TRA2B 0.8662104375 3.205397e-10 0.2357465745
1207 Q5T440 IBA57 -0.3729151474 1.173489e-02 0.1572735744
1208 P33992 MCM5 2.5385286100 7.953892e-08 -0.4266690391
1209 Q9H1C7 CYSTM1 -0.5429026984 1.530673e-02 -0.2042284216
1210 Q99805 TM9SF2 0.0518010183 7.881137e-01 -0.2996303088
1211 Q9HCG7 GBA2 0.1452445581 5.913134e-01 0.6715095217
1212 Q7Z434 MAVS 0.1179006213 5.258659e-01 -0.2201294849
1213 O95140 MFN2 0.6211688186 1.353209e-03 0.1736514536
1214 P67936 TPM4 0.7288517470 1.204219e-01 -1.3145986683
1215 Q9NW81 DMAC2 0.4249282327 3.640322e-02 0.7093298005
1216 P06744 GPI 0.5731296492 1.195410e-01 0.2989626569
1217 P11388 TOP2A 2.5453095174 4.335829e-07 0.2831782862
1218 Q8IXI1 RHOT2 0.2257658276 2.679636e-01 0.1829881949
1219 Q86UT6 NLRX1 -1.4935468157 1.188060e-09 0.1727044734
1220 P61289 PSME3 -0.1551700705 2.936398e-01 -0.3186488922
1221 O00264 PGRMC1 -0.1643681228 5.832608e-01 -0.3144666001
1222 O96011 PEX11B 0.2246029516 2.006356e-01 -0.4070909886
1223 Q9Y2R0 COA3 0.7124130525 9.633384e-03 -1.0563885795
1224 O43837 IDH3B -0.2117197571 2.465050e-01 0.1745584763
1225 Q9Y625 GPC6 2.1561393996 5.386425e-08 -0.5029000042
1226 Q86T03 PIP4P1 -0.1920107847 2.215834e-01 0.2361481036
1227 Q9BZL4 PPP1R12C -0.1722368676 4.060347e-01 -0.4609433229
1228 Q9H425 C1orf198 0.1918442593 4.730758e-01 -0.2446437360
1229 P29373 CRABP2 -0.5694131325 1.275539e-01 0.5833966568
1230 O00483 NDUFA4 -0.0935414601 8.187737e-01 -0.1548613881
1231 Q9BVL2 NUP58 -0.0962208544 5.154703e-01 0.4128067530
1232 Q8NBJ9 SIDT2 -2.1821899647 4.994420e-11 0.1777699194
1233 P49406 MRPL19 0.3354281979 3.559057e-02 -0.1866633396
1234 Q8IX03 WWC1 -1.6684211550 8.573148e-04 -0.5816565682
1235 Q10472 GALNT1 0.0221855095 9.321867e-01 -0.3390812803
1236 Q02878 RPL6 -0.1665519442 2.233610e-01 -0.1699608569
1237 P20339 RAB5A -0.4581357504 2.769122e-03 -0.1952687252
1238 Q8NBI6 XXYLT1 0.2742338750 1.110262e-01 0.2879622067
1239 Q96PK6 RBM14 -0.0882873299 7.646341e-01 -0.1602658956
1240 P12236 SLC25A6 0.3566280473 7.825277e-02 0.2312047675
1241 Q9Y6E2 BZW2 0.7262709175 1.363170e-02 0.4040859421
1242 Q8IVH4 MMAA -0.6684583600 8.023218e-05 0.4118128987
1243 Q8N357 SLC35F6 -0.1557783728 5.992235e-01 -0.9284861958
1244 Q96RL7 VPS13A 0.1572218831 4.644663e-01 0.2389143229
1245 Q00796 SORD -0.2923900264 2.679636e-01 0.2646324357
1246 Q9Y281 CFL2 0.4869382091 5.488877e-02 -0.2704586228
1247 P30043 BLVRB -2.0859019736 1.324293e-11 0.4176070938
1248 Q7RTV0 PHF5A -0.3088479011 8.362302e-02 0.1821132685
1249 P31689 DNAJA1 -0.6821528472 2.591641e-06 -0.1702417740
1250 O95182 NDUFA7 -0.3041434870 4.695476e-01 -0.2823055399
1251 Q70UQ0 IKBIP -2.5968791300 1.312041e-08 -0.4258268925
1252 Q01130 SRSF2 1.3161428264 2.203715e-13 -0.1757609362
1253 Q8IUW5 RELL1 -0.9659703540 5.544404e-03 0.4383245957
1254 Q15700 DLG2 0.2863520456 4.632790e-01 0.3382206433
1255 Q01844 EWSR1 0.3213996649 1.945372e-03 -0.1795997354
1256 Q63ZY3 KANK2 -0.1363736576 6.866698e-01 0.2702748502
1257 Q9UGJ0 PRKAG2 0.7936863964 2.199838e-04 0.2038104192
1258 Q9NZW5 PALS2 -0.1629946832 5.024194e-01 -0.3516237777
1259 Q8N335 GPD1L -1.3979714290 5.775641e-06 0.2670420996
1260 Q9UBW7 ZMYM2 -0.3256196612 8.150065e-02 -0.8711726993
1261 O95197 RTN3 0.5732234253 5.001978e-05 0.1595146606
1262 O94906 PRPF6 -0.0631869873 6.972857e-01 -0.2087853647
1263 P53007 SLC25A1 -0.0156444912 9.432795e-01 0.1674328582
1264 P09622 DLD 0.5596219860 1.646930e-02 0.1663956233
1265 Q9HBL0 TNS1 1.5841964540 6.973185e-05 -0.2565113346
1266 O15173 PGRMC2 0.8576537752 1.729944e-05 -0.2180495810
1267 O60869 EDF1 0.0935117587 5.358371e-01 0.3151733118
1268 Q9NYK5 MRPL39 -1.1662315660 3.597863e-06 -0.1484128380
1269 Q96PD2 DCBLD2 0.1316710309 6.968809e-01 -0.7323248288
1270 A4D1E9 GTPBP10 0.2891125963 1.640769e-01 -0.2908210346
1271 P82930 MRPS34 1.0870852877 2.162139e-07 -0.2525067136
1272 Q9Y4F1 FARP1 0.5041133248 1.693429e-02 0.2126862545
1273 P28070 PSMB4 -0.3870507288 1.778245e-03 0.1913990895
1274 O15371 EIF3D -0.1383335046 3.323825e-01 -0.1797804518
1275 O95229 ZWINT 2.1556045824 3.197079e-06 -0.2296707827
1276 P24752 ACAT1 -0.0248016224 9.225443e-01 0.1822936202
1277 Q92621 NUP205 1.2512749595 1.883758e-07 0.1957930676
1278 Q9NZ08 ERAP1 -1.0814621888 7.124195e-04 0.2536459915
1279 Q9UKX5 ITGA11 0.0411507027 9.696183e-01 -0.8492074981
1280 Q9NXF1 TEX10 -1.2219378568 1.730844e-07 -0.1956753243
1281 O60830 TIMM17B 0.4848448634 8.123777e-02 0.2971402877
1282 Q8IYK4 COLGALT2 0.2996215758 5.029982e-01 0.3103938096
1283 P29590 PML -2.0234028242 1.022548e-10 -0.8965424131
1284 Q9BUB7 TMEM70 -0.1382877334 5.086063e-01 0.1737179212
1285 Q9UHG3 PCYOX1 -0.0941640821 7.066130e-01 0.1451491849
1286 Q9UGM6 WARS2 -0.0220872871 9.065459e-01 0.2278769792
1287 Q14161 GIT2 -0.5935467767 1.131321e-03 0.3041902391
1288 P16070 CD44 -0.6017436142 2.437847e-01 0.4748070915
1289 Q96GG9 DCUN1D1 -0.5363147019 2.054383e-03 -0.2413307076
1290 Q9P0V9 SEPTIN10 -0.1467395687 5.602139e-01 0.3817066867
1291 P20674 COX5A 0.3123204036 2.851546e-01 -0.2240857927
1292 Q96AG4 LRRC59 -0.0065760286 9.811304e-01 -0.3024427746
1293 Q13510 ASAH1 0.1920116213 4.885160e-01 0.1810344084
1294 Q13740 ALCAM 0.6736856725 6.164576e-03 0.2368755761
1295 P61981 YWHAG -0.5825967230 5.124475e-04 -0.4018363757
1296 P05362 ICAM1 -3.1728344444 2.136255e-06 0.2277610361
1297 Q9BV81 EMC6 -0.4998517862 1.058354e-01 0.1921134483
1298 Q9P0J1 PDP1 -1.0137644623 2.814159e-07 0.1966753339
1299 P28074 PSMB5 -0.1744676482 1.875239e-01 0.1752998970
1300 P51798 CLCN7 -0.5351607685 1.358450e-02 -0.3937373400
1301 P14678 SNRPB -0.0171175039 9.485996e-01 -0.4266921252
1302 Q8WWY3 PRPF31 0.1817990400 1.877427e-01 -0.4769448034
1303 Q9BQE5 APOL2 0.1695596533 7.560025e-01 -0.4092360678
1304 P48552 NRIP1 -0.3031652618 1.394605e-01 0.3734020518
1305 Q92552 MRPS27 0.4896357530 5.956966e-06 -0.2499214918
1306 Q14669 TRIP12 -0.3217735245 2.396917e-03 -0.2132298260
1307 O95470 SGPL1 0.6106090065 2.816802e-03 -0.1458601456
1308 Q99590 SCAF11 0.4355917717 1.465209e-04 -0.5391192012
1309 P20073 ANXA7 0.2067953861 1.557194e-01 0.1856541714
1310 Q9Y6M1 IGF2BP2 0.4028236776 3.489404e-02 -0.1551044830
1311 Q9Y6Y0 IVNS1ABP -0.3483677379 1.585645e-01 0.1997982639
1312 P51589 CYP2J2 1.7911017443 1.188032e-03 -0.2083323637
1313 O75521 ECI2 -0.4605854024 6.925060e-03 0.1756689741
1314 P07711 CTSL -1.1932420348 2.660594e-05 0.1734064100
1315 Q9Y2W1 THRAP3 0.2584578608 1.147468e-01 -0.1526553555
1316 O15321 TM9SF1 0.2913228563 1.101212e-01 -0.5116488542
1317 P07237 P4HB 0.0540833049 8.043185e-01 0.1847757544
1318 P11717 IGF2R -0.6547762061 3.621031e-02 0.1760794914
1319 Q96A33 CCDC47 -0.0096495394 9.594684e-01 0.1839611026
1320 P51797 CLCN6 0.3068992915 7.583298e-02 -0.1437019702
1321 Q16134 ETFDH 0.1294769884 5.078204e-01 0.1691107558
1322 P13473 LAMP2 -0.0788987806 8.028234e-01 0.2558898146
1323 P52565 ARHGDIA -0.1099337515 7.084320e-01 0.1995929713
1324 P12004 PCNA -2.3246891718 6.129513e-12 0.2918815492
1325 Q9H6R3 ACSS3 0.4830666754 8.960703e-02 0.3293744375
1326 Q9H0U4 RAB1B 0.1402863905 2.887879e-01 -0.2557982811
1327 Q04637 EIF4G1 -0.1270788032 5.813380e-01 -0.1770725141
1328 Q6PML9 SLC30A9 0.1291828830 3.908375e-01 0.2414028600
1329 O00330 PDHX 0.0969681201 6.221394e-01 0.1818020732
1330 Q92878 RAD50 0.3013301993 1.539666e-01 -0.1886612531
1331 O43462 MBTPS2 0.9315136933 3.968384e-04 0.5602075722
1332 Q9H6F2 TMEM38A 0.4916124969 4.728673e-01 -0.4337233743
1333 P15121 AKR1B1 -0.2020262208 4.922021e-01 0.2168163302
1334 Q9NXE4 SMPD4 0.0245570685 8.854080e-01 0.3238087856
1335 Q8NEY8 PPHLN1 -0.7712157819 2.933686e-09 -0.2846316844
1336 Q13011 ECH1 0.0072142691 9.874831e-01 0.1774794224
1337 Q6NUQ4 TMEM214 0.2922292584 2.573985e-01 -0.2497138415
1338 P35658 NUP214 0.1114429427 5.316200e-01 0.1660316066
1339 Q567V2 MPV17L2 0.2715510733 7.679599e-02 -0.4270998235
1340 P61026 RAB10 0.8730113488 1.016052e-11 -0.1545494103
1341 Q6IAN0 DHRS7B 0.7459477690 3.290862e-07 -0.2038991202
1342 Q9Y3C6 PPIL1 0.4085145307 6.532447e-03 -0.4545700983
1343 Q9Y2S7 POLDIP2 -0.4774891546 5.888724e-07 0.2446095314
1344 P27824 CANX -0.1205830583 6.654446e-01 0.1711955194
1345 P63316 TNNC1 0.3950433855 3.828440e-01 -0.7257889002
1346 Q9H857 NT5DC2 -0.2455237401 2.135304e-01 0.1577193899
1347 Q9HB90 RRAGC -1.1930258462 5.051989e-08 0.1880983245
1348 Q9H3Z4 DNAJC5 -0.9422654275 2.119777e-04 -0.2396861754
1349 Q96HS1 PGAM5 0.7857049495 3.790385e-05 -0.1866335481
1350 P61964 WDR5 -0.0092351371 9.538291e-01 -0.1763420126
1351 Q5JWF2 GNAS -0.6305427339 4.178859e-04 0.1934172414
1352 Q01433 AMPD2 0.5567075681 1.992546e-03 0.3305181281
1353 Q9H2D6 TRIOBP 0.0427631222 8.567453e-01 0.1517306753
1354 P46087 NOP2 0.2945846607 1.998767e-01 -0.1703746942
1355 Q13057 COASY -0.1409929830 2.111999e-01 0.2133141718
1356 P22694 PRKACB -0.1742394335 2.677860e-01 -0.4304415165
1357 P60602 ROMO1 -0.3041029275 2.803242e-01 0.2595738896
1358 Q9UPT5 EXOC7 -0.7633202347 1.107584e-07 0.3537433291
1359 Q96BW9 TAMM41 1.8801846809 3.284402e-07 0.3625873956
1360 Q53EU6 GPAT3 -0.2746935698 4.102683e-01 -0.1526359695
1361 P51114 FXR1 0.2749105225 1.145534e-01 -0.1340646006
1362 Q13619 CUL4A 0.2717370544 1.213938e-02 -0.2727849206
1363 Q6L8Q7 PDE12 -0.3078127710 3.495553e-02 -0.4039064278
1364 Q96RQ1 ERGIC2 0.5416732220 7.785810e-03 -0.2213488910
1365 P12109 COL6A1 -0.3308760927 2.249124e-01 -0.1924487788
1366 Q96QK1 VPS35 -0.1229776835 4.482536e-01 0.1806870857
1367 Q16698 DECR1 0.1255539034 6.197637e-01 0.1528159549
1368 P49257 LMAN1 0.3622248162 1.360145e-01 0.1633911931
1369 O75436 VPS26A -0.4446357587 2.194143e-02 0.2470100373
1370 P49821 NDUFV1 -0.1739867927 3.974064e-01 0.1445148178
1371 P60033 CD81 0.2138264116 1.873557e-01 0.2014163689
1372 P84095 RHOG 0.0130944774 9.440755e-01 -0.2018248668
1373 Q15836 VAMP3 -0.4501115145 8.462332e-03 -0.1669144692
1374 P42765 ACAA2 -0.0097654094 9.531766e-01 0.1658497680
1375 O95777 LSM8 -0.1232393564 5.871844e-01 -0.3627875751
1376 Q9UG63 ABCF2 -0.1793084711 2.923517e-01 -0.3198460718
1377 P23471 PTPRZ1 -1.8380208226 4.134054e-02 0.3306605987
1378 Q9BV35 SLC25A23 0.4919305499 1.840405e-01 0.1495701720
1379 O43909 EXTL3 -0.2417633874 2.016974e-01 -0.2588645770
1380 Q8TBC4 UBA3 -0.4470115703 1.081952e-02 0.2740878873
1381 P11142 HSPA8 -0.1120909167 5.556990e-01 0.1375474911
1382 P30048 PRDX3 0.4574038642 3.688970e-02 0.1356290773
1383 Q9H173 SIL1 -0.0528623030 8.260484e-01 -0.4179321655
1384 Q86VP6 CAND1 -0.0397175883 8.171965e-01 0.1834502649
1385 Q6ZNB6 NFXL1 0.2699386779 1.299681e-01 -0.3242395030
1386 P51610 HCFC1 0.0139026053 9.560853e-01 0.1934506828
1387 O96019 ACTL6A 0.3714181468 9.080026e-02 -0.1489503500
1388 Q9BZZ5 API5 -0.0899678184 5.555046e-01 -0.1696430939
1389 Q8N983 MRPL43 0.2037530918 2.558748e-01 -0.3774227433
1390 Q96GD0 PDXP 0.7840934441 4.605458e-03 0.7947308803
1391 P55735 SEC13 0.5422210806 1.305824e-03 0.1385605348
1392 Q96PE7 MCEE -0.0298643257 9.399329e-01 0.3123543318
1393 P19021 PAM 0.0596644561 8.344395e-01 -0.2202004135
1394 Q9NPH3 IL1RAP -1.0472359928 5.965804e-04 0.3338440517
1395 Q08J23 NSUN2 -0.1666072327 3.454471e-01 -0.1676191426
1396 Q08623 PUDP -0.3650137374 4.738124e-02 0.7666161069
1397 Q13439 GOLGA4 0.0871495074 5.805587e-01 0.2066317185
1398 Q5JR59 MTUS2 1.3856369471 1.123932e-03 0.3573558785
1399 P07942 LAMB1 0.7587264630 1.699551e-02 -0.2046992466
1400 O43491 EPB41L2 0.4950260111 2.675653e-01 0.3757262075
1401 Q6YN16 HSDL2 -0.6335113257 8.462332e-03 0.1525930061
1402 O95793 STAU1 -0.3752495163 3.461841e-02 -0.1779168350
1403 P54725 RAD23A 0.7934363991 1.194638e-04 -0.2013385424
1404 P28482 MAPK1 -0.3116937867 1.910829e-02 0.2054883472
1405 Q10570 CPSF1 0.1310133571 3.689465e-01 -0.2038856728
1406 Q9UK45 LSM7 -0.0900907482 7.426571e-01 -0.2177406623
1407 Q9BXJ8 TMEM120A 0.2358585935 5.965741e-02 0.4556479812
1408 Q9NX47 MARCHF5 -0.1759985128 1.230138e-01 -0.2048633444
1409 Q9BYW2 SETD2 0.3276360164 3.156658e-02 -0.2219309686
1410 P06737 PYGL -1.2697589330 2.164541e-09 0.3214946498
1411 P20336 RAB3A 0.9973077526 1.337983e-02 -0.5551680429
1412 Q6UX07 DHRS13 0.1807359059 6.515495e-01 -0.3932751306
1413 Q8IVF2 AHNAK2 -0.8311904374 3.302512e-02 -0.3026347170
1414 Q9UDX5 MTFP1 0.6562423049 1.186882e-01 -0.2319046639
1415 Q9H3G5 CPVL 0.1390151955 6.623457e-01 0.1249858773
1416 Q9UEY8 ADD3 0.6324864962 1.181397e-02 0.1931230260
1417 P52209 PGD -1.1149314800 2.243988e-07 0.2922302106
1418 P53597 SUCLG1 0.6181336384 1.993105e-02 0.1912003732
1419 A4UGR9 XIRP2 2.4905258168 1.119086e-01 -0.2269443773
1420 O43854 EDIL3 0.2860416366 7.718964e-01 -0.3948449302
1421 Q969H8 MYDGF 0.0387146865 9.418177e-01 0.1947359574
1422 O76024 WFS1 0.0547337907 8.089624e-01 -0.1828645648
1423 Q9BSD7 NTPCR -0.6238779689 1.930237e-03 0.1944969932
1424 P31930 UQCRC1 0.2519176584 1.997361e-01 0.1739632470
1425 Q6NUK1 SLC25A24 0.9003719479 4.596853e-06 0.1706370371
1426 P14868 DARS1 0.5050206219 9.628551e-02 0.1276870681
1427 Q9Y2Q3 GSTK1 0.2043138029 3.395401e-01 -0.2347226597
1428 Q99829 CPNE1 0.0429119650 8.451320e-01 0.4119754421
1429 O43181 NDUFS4 0.7052030058 7.656405e-03 0.1399504432
1430 P40937 RFC5 1.3275675619 1.047054e-06 -0.3457421561
1431 Q49A88 CCDC14 0.8631370897 2.526654e-04 -0.3769303003
1432 P48444 ARCN1 -0.3134527240 2.437644e-01 0.1787571873
1433 A6NDG6 PGP 0.8445219568 5.148613e-03 0.9020558768
1434 Q86Y39 NDUFA11 -0.1473201374 7.231248e-01 0.1442489499
1435 P68133 ACTA1 1.9681486393 1.453014e-01 0.4065555948
1436 Q5BJD5 TMEM41B 0.2687774711 1.039667e-01 -0.1146413565
1437 O95167 NDUFA3 0.1116812849 7.479148e-01 0.3819258261
1438 Q9Y277 VDAC3 0.2182083325 4.139644e-01 0.1423087293
1439 Q03252 LMNB2 1.5270141096 5.232113e-08 0.1300332666
1440 Q9BQ52 ELAC2 0.4683545774 1.747223e-03 -0.1714179530
1441 Q8IYB8 SUPV3L1 -0.1791004805 8.290764e-02 0.1695546343
1442 P22830 FECH -0.0814246543 7.846933e-01 0.1696781285
1443 Q96HY6 DDRGK1 0.6580762653 2.821087e-03 -0.4241305396
1444 Q99807 COQ7 -0.0106316375 9.607669e-01 -0.3499586745
1445 Q6ZXV5 TMTC3 -0.5770581993 2.636265e-02 -0.1219694750
1446 P26440 IVD 0.2984579133 3.460452e-02 0.1345680756
1447 P30405 PPIF -0.2204973612 2.591195e-01 0.1722444477
1448 Q8N490 PNKD 0.8205032256 1.784634e-04 0.2143259695
1449 Q8WUY1 THEM6 2.8374047428 3.205397e-10 -0.2366917099
1450 P56545 CTBP2 -0.2272613345 1.530905e-01 -0.1586315023
1451 Q9NNW7 TXNRD2 0.1932756669 6.509988e-01 0.2203412051
1452 P61163 ACTR1A 0.0264030234 8.576817e-01 0.1568730927
1453 Q5ZPR3 CD276 -0.7487156798 2.005037e-02 0.5294558186
1454 O43674 NDUFB5 0.1820378276 5.484705e-01 -0.2400599582
1455 P49755 TMED10 0.2785278679 8.919661e-02 0.2606131025
1456 Q9H7F0 ATP13A3 0.3887749942 1.328384e-01 -0.2814472256
1457 P52594 AGFG1 -0.3955555234 3.642568e-03 0.2251423360
1458 P11586 MTHFD1 1.4447541588 8.308105e-09 0.4097285533
1459 P17987 TCP1 0.2282805566 1.236860e-01 0.1599648738
1460 P09960 LTA4H -0.5960658362 1.122294e-05 0.3374283381
1461 Q96GQ5 RUSF1 0.2195671986 2.168049e-01 -0.2735823428
1462 Q14524 SCN5A 2.0508096541 1.805189e-11 -0.1783913409
1463 Q9HCC0 MCCC2 0.2788300967 4.161078e-02 0.1479036002
1464 P41247 PNPLA4 -0.3265835033 2.710520e-01 -0.5672004033
1465 Q08722 CD47 0.2526191664 2.082809e-01 0.1833158546
1466 Q13393 PLD1 0.3617911813 6.623782e-02 -0.3781307178
1467 Q10567 AP1B1 -0.2948061186 3.248651e-02 0.1634320972
1468 Q13464 ROCK1 0.1933406902 3.032811e-01 0.5412345970
1469 P30101 PDIA3 0.0086654019 9.829745e-01 0.1539244082
1470 Q15428 SF3A2 0.4164544855 1.497359e-02 -0.4168327023
1471 Q9Y696 CLIC4 0.5348426386 9.324176e-02 -0.2644762835
1472 Q969M3 YIPF5 -0.2321594888 1.445567e-01 -0.3183726759
1473 P53680 AP2S1 0.1359370191 5.511424e-01 -0.1748212375
1474 O95571 ETHE1 0.0812171329 7.829920e-01 0.2042071532
1475 O15258 RER1 -0.2121602638 1.700926e-01 0.2946458440
1476 O60231 DHX16 -0.0501905240 8.435382e-01 -0.3615133076
1477 Q96SN8 CDK5RAP2 0.5107350974 5.425311e-03 -0.3990717083
1478 Q9P2R7 SUCLA2 -0.0874001242 7.094227e-01 0.1511876257
1479 P80404 ABAT 1.4912747864 1.197906e-04 0.2589337745
1480 P37802 TAGLN2 -0.1809339725 8.384457e-01 0.4247578463
1481 Q92736 RYR2 1.4501324771 1.612760e-03 0.1583752804
1482 Q9BWF3 RBM4 -0.4178381394 3.868243e-04 -0.1708557213
1483 P35268 RPL22 0.0289640361 8.893281e-01 -0.1314736851
1484 P08240 SRPRA 0.3773784764 2.388333e-02 -0.1640100525
1485 O94901 SUN1 0.3554365020 2.368120e-02 0.1897139185
1486 Q96E11 MRRF 0.5421217999 1.662836e-04 -0.3547290681
1487 P35237 SERPINB6 0.0991143007 7.020432e-01 0.2123020967
1488 O00217 NDUFS8 0.6085900117 3.558259e-03 -0.1497285352
1489 Q9BX79 STRA6 0.5684384079 1.020726e-01 0.6251707481
1490 P30086 PEBP1 -0.0420223739 7.966408e-01 0.1829728813
1491 Q9Y3B7 MRPL11 0.2162217405 2.496476e-01 -0.1826969056
1492 Q13162 PRDX4 0.0255711551 9.130904e-01 0.1387678869
1493 Q9Y3I0 RTCB -0.0168064298 8.991323e-01 0.1354217771
1494 P19367 HK1 0.1868705214 2.115534e-01 0.1356042458
1495 Q8WTW3 COG1 -0.7135336175 3.992086e-05 -0.2163136486
1496 Q6IN85 PPP4R3A -0.7114568332 2.414227e-07 -0.2935051522
1497 Q15388 TOMM20 0.4729087275 1.634914e-05 -0.1997517294
1498 O43143 DHX15 0.4069308591 1.662068e-02 -0.1478656322
1499 P20042 EIF2S2 -0.2851062205 3.121713e-02 -0.1697867618
1500 P30046 DDT 0.0677336758 8.526218e-01 0.2232652366
1501 Q06210 GFPT1 0.4511681733 2.975976e-03 0.3592277349
1502 P61916 NPC2 -0.0996592680 6.254355e-01 0.1578093580
1503 Q96G23 CERS2 -0.0215797878 9.420915e-01 -0.2733087334
1504 P51531 SMARCA2 -0.0587417454 8.036622e-01 -0.2662306396
1505 P45379 TNNT2 0.7515131141 3.732140e-02 -0.4203079802
1506 Q6UW56 ATRAID 0.1256591601 4.701730e-01 1.1206318431
1507 Q96AC1 FERMT2 0.3692665404 1.501799e-01 0.2279536937
1508 O00622 CCN1 0.1272558401 8.353794e-01 -0.5884289392
1509 Q86VI1 EXOC3L1 -1.2006507244 1.226800e-06 -0.1922496341
1510 P14550 AKR1A1 -0.3938676776 1.021968e-02 0.2049176888
1511 Q5JVF3 PCID2 -0.3185466867 2.395503e-02 -0.4192457029
1512 Q9Y6Y8 SEC23IP 0.4037452180 5.279361e-04 0.2575344642
1513 O94979 SEC31A -0.4285633093 4.107315e-02 0.1403036475
1514 O15260 SURF4 -0.1275905789 5.698260e-01 0.3828737024
1515 Q6UW63 POGLUT2 -0.0636772305 8.703472e-01 0.3718952595
1516 Q8IWA6 CCDC60 -4.6017447645 4.289264e-10 -1.1748616520
1517 P30044 PRDX5 -0.0877710188 7.138991e-01 -0.1875597915
1518 P02511 CRYAB 0.0846854044 9.036887e-01 -0.2649749515
1519 Q92947 GCDH 0.2600129387 6.522259e-02 0.1404295768
1520 P63010 AP2B1 -0.1904118329 2.351845e-01 0.1265583997
1521 Q9NQZ5 STARD7 0.9291376490 1.107584e-07 0.2768460770
1522 Q9Y5L0 TNPO3 0.1283966114 4.922021e-01 0.4084989557
1523 P23634 ATP2B4 0.7035487050 2.629039e-03 0.1578526585
1524 Q9Y2Z0 SUGT1 0.0500726171 7.965814e-01 0.2626134284
1525 Q01469 FABP5 -1.1102514606 1.147383e-04 0.3199039862
1526 Q8N5M9 JAGN1 -0.1004521192 4.678910e-01 0.4211300832
1527 P53634 CTSC 1.0805573904 4.738244e-04 0.1530751873
1528 Q9BW27 NUP85 0.4593943340 3.535362e-03 -0.3112330991
1529 P42345 MTOR 0.2528124985 1.059118e-01 0.1964298987
1530 P02461 COL3A1 0.4045696891 6.993849e-01 -0.5581871743
1531 Q86TV6 TTC7B 0.6734697249 7.133974e-04 0.3567904027
1532 Q96HN2 AHCYL2 0.0442939064 9.065459e-01 -0.3380675936
1533 Q9ULX6 AKAP8L -0.5915065004 1.177978e-03 -0.2131864988
1534 O00192 ARVCF -0.9811165019 6.272316e-04 0.2773729555
1535 P31153 MAT2A -0.0861283860 6.566185e-01 -0.2944864528
1536 Q8IY17 PNPLA6 0.6232170572 2.038740e-03 0.3219863805
1537 Q9NR28 DIABLO -0.1294132569 3.995054e-01 0.2193858814
1538 Q71UM5 RPS27L -1.2890953658 1.295235e-06 -0.2213285426
1539 Q13724 MOGS 0.3327314626 1.800319e-01 0.2510442243
1540 Q13443 ADAM9 0.0573339019 9.190308e-01 0.3483369572
1541 P00568 AK1 -0.5484053712 9.717693e-03 0.2295284048
1542 Q9NUT2 ABCB8 0.1839095756 3.858076e-01 0.2707294449
1543 Q13889 GTF2H3 0.0857315799 5.819400e-01 -0.3737205849
1544 Q14254 FLOT2 0.1682379007 2.402563e-01 0.1844702112
1545 Q14204 DYNC1H1 -0.4361423594 4.284663e-02 0.1747237411
1546 P42785 PRCP 0.4586363716 6.983123e-02 0.1266610913
1547 O15498 YKT6 0.0774974883 6.761154e-01 0.1263343407
1548 O14662 STX16 -0.7371742180 5.786007e-06 0.2403507390
1549 Q8N684 CPSF7 -0.1302151618 3.789783e-01 -0.1642694784
1550 Q9UBY9 HSPB7 1.7573820921 4.612292e-04 0.1989696848
1551 Q6ZVM7 TOM1L2 -0.0449998063 8.627737e-01 -0.2152424473
1552 Q14642 INPP5A 0.0321604204 8.924107e-01 -0.2024959410
1553 Q6NXT4 SLC30A6 0.1463722928 2.982599e-01 -0.1869593310
1554 A1A4S6 ARHGAP10 -0.8139164783 9.576317e-05 1.2569154842
1555 Q9UPN3 MACF1 0.1208039512 7.315256e-01 -0.1655102239
1556 Q13435 SF3B2 -0.2478010756 6.256746e-02 -0.1225704779
1557 Q9Y4J8 DTNA 0.9401594234 3.984492e-03 -0.1627755026
1558 Q96ST3 SIN3A 0.2346134317 3.711127e-01 0.2459319442
1559 Q8NFQ8 TOR1AIP2 -0.2509775227 7.310169e-02 -0.2140915439
1560 P58107 EPPK1 -1.5092236644 8.093815e-03 0.4440944221
1561 Q9Y3A6 TMED5 0.5103033760 2.647971e-03 0.2499658609
1562 Q9NW13 RBM28 1.0108039937 6.077584e-09 -0.6322504970
1563 Q5MNZ6 WDR45B -0.1011004976 3.426630e-01 0.2034250198
1564 A8MXV4 NUDT19 0.7973983737 3.571356e-02 -0.4131167536
1565 Q15370 ELOB -0.2393897686 3.343181e-01 -0.2629063161
1566 Q5THK1 PRR14L -0.5239246509 2.021663e-02 -0.1619819506
1567 P31939 ATIC 0.6337753900 2.000627e-09 0.2781767762
1568 Q6QEF8 CORO6 0.0562593217 9.144368e-01 0.1717452486
1569 Q8IWB1 ITPRIP 0.7037180359 1.527445e-02 0.2640393362
1570 O75179 ANKRD17 0.1376580118 3.816490e-01 -0.1393212043
1571 O00165 HAX1 0.8693445690 1.393538e-03 -0.1896560845
1572 Q96GE9 DMAC1 0.1861130148 6.435786e-01 -0.4584078011
1573 Q9HD20 ATP13A1 -0.5854556919 9.972490e-03 -0.1919268814
1574 Q96M27 PRRC1 0.4152923823 1.291836e-02 0.1731613968
1575 O75843 AP1G2 -0.3715774646 1.451499e-01 0.2032373336
1576 Q9P0J0 NDUFA13 -0.1316382177 6.646525e-01 -0.1482501119
1577 Q14247 CTTN -0.3246142023 2.976993e-01 0.2038126527
1578 Q9HA77 CARS2 0.3897356747 3.252390e-02 0.1418524862
1579 Q92542 NCSTN -0.2322432808 3.148938e-01 0.2264951318
1580 Q16401 PSMD5 -0.1060433484 7.880189e-01 0.7614004148
1581 P11166 SLC2A1 0.2690211584 5.706415e-01 -0.3401007616
1582 P48735 IDH2 0.0025445494 9.946207e-01 0.1456566581
1583 Q9H488 POFUT1 0.4356741765 2.200447e-02 0.1394492596
1584 Q9P265 DIP2B 0.2760783862 1.736875e-01 0.1794882687
1585 Q6ZWT7 MBOAT2 0.1662557261 2.266774e-01 -0.3284056844
1586 P04792 HSPB1 0.2672958343 4.574401e-01 0.2102243181
1587 Q9BQP7 MGME1 -0.6384503973 6.115062e-06 -0.2150802840
1588 P61019 RAB2A 0.1966666795 1.480561e-01 -0.1386995442
1589 Q9Y385 UBE2J1 0.3700648637 2.208082e-01 -0.2023316616
1590 O94919 ENDOD1 -1.7729211535 6.177175e-07 0.1846416190
1591 P35625 TIMP3 0.8462492444 1.375839e-01 -0.6193118089
1592 Q9UIQ6 LNPEP 0.2024059429 4.499877e-01 0.1698605945
1593 Q9H1B7 IRF2BPL -0.5750532066 7.417813e-04 -0.2046320465
1594 Q9Y3F4 STRAP -0.1374830759 1.356946e-01 -0.3711372142
1595 Q6ZVF9 GPRIN3 2.3992186463 4.465813e-04 -0.2456349172
1596 Q08AM6 VAC14 0.0394764028 7.755739e-01 0.4518592849
1597 Q9UBB4 ATXN10 -0.0507787396 7.096562e-01 0.3456520334
1598 P21964 COMT 0.0006917953 9.988233e-01 -0.3590790930
1599 Q32P28 P3H1 -0.7234915878 2.083102e-01 0.3567368899
1600 Q8IUG5 MYO18B 0.7194227033 2.015646e-03 -0.1424573779
1601 P45973 CBX5 1.5111264349 5.550083e-12 0.2489579868
1602 P50570 DNM2 0.0695868180 6.585118e-01 0.1291995546
1603 P48382 RFX5 0.1321931302 3.719748e-01 0.1798371745
1604 Q9HB71 CACYBP 0.6176745477 4.182411e-03 0.1435524358
1605 Q9NYL2 MAP3K20 0.5086511034 1.182328e-01 0.2512525141
1606 Q96AY3 FKBP10 0.4467243427 1.113112e-01 0.2029690883
1607 Q15526 SURF1 -0.8715337838 9.907168e-06 0.2087570688
1608 P56192 MARS1 0.4166693182 1.134044e-03 0.1177502284
1609 P16278 GLB1 0.1732844191 4.753941e-01 0.1844768679
1610 Q14697 GANAB -0.1566748974 6.054961e-01 0.1132188809
1611 Q9BZ29 DOCK9 0.0382882737 9.237096e-01 1.0994459896
1612 Q96F07 CYFIP2 -1.1786946446 8.220763e-05 0.3947110352
1613 O43396 TXNL1 -0.1761030215 1.065178e-01 0.2121736850
1614 Q9Y4K0 LOXL2 -0.3363789099 1.677229e-01 0.3820621333
1615 Q9UIJ7 AK3 -0.6608146256 4.135304e-05 -0.1892167283
1616 P09669 COX6C -0.1894286858 6.067403e-01 -0.3073166158
1617 P25788 PSMA3 -0.2976410304 9.860888e-02 0.1358267045
1618 O75380 NDUFS6 0.2241556251 4.170884e-01 -0.1519854196
1619 Q12797 ASPH 0.7468930503 2.666929e-02 0.2677206428
1620 O00487 PSMD14 0.6560064802 2.822175e-04 -0.1276894010
1621 P51858 HDGF 1.0238409074 7.757876e-11 0.2814176576
1622 P98179 RBM3 0.3710102267 2.595213e-01 -0.1994485307
1623 Q96EY4 TMA16 -0.2307161639 2.740189e-01 -0.3853440432
1624 P56937 HSD17B7 -1.0319086106 5.613777e-06 0.3108440907
1625 Q5JTV8 TOR1AIP1 0.5452031019 4.412361e-04 -0.4057918444
1626 Q2KHT3 CLEC16A -0.7256892280 5.099687e-04 0.1885129287
1627 Q9HC77 CENPJ 1.6345556701 4.937728e-08 -0.1489839924
1628 Q9H2U2 PPA2 0.5632870030 1.752156e-02 0.1786945349
1629 P30519 HMOX2 -0.5668095686 1.666777e-03 -0.2172233972
1630 P51689 ARSD -0.1068071500 5.108484e-01 0.2628487810
1631 Q5JS37 NHLRC3 1.4873507233 2.630120e-10 0.1329728029
1632 P31431 SDC4 -1.1900302931 9.106766e-07 0.3291979286
1633 Q7Z7K6 CENPV 1.0392761420 3.544615e-03 0.2808150998
1634 P62314 SNRPD1 0.7718443987 7.409111e-04 -0.2341272132
1635 O95447 LCA5L -0.0860953128 8.787568e-01 0.5482526245
1636 P10809 HSPD1 0.5156892316 8.698080e-03 0.1505143852
1637 O95139 NDUFB6 0.1670298208 5.954926e-01 -0.1543210621
1638 Q7L576 CYFIP1 -0.1579722296 7.277515e-01 0.1759483154
1639 Q969T9 WBP2 0.1029774584 5.470422e-01 -0.7229710435
1640 Q15904 ATP6AP1 0.0780591274 7.842824e-01 0.2328552920
1641 P56199 ITGA1 -0.7914205536 2.987471e-01 0.3363279060
1642 A6ZKI3 RTL8C 0.2674308784 1.598083e-01 0.3862971555
1643 P00505 GOT2 0.6650423493 4.266416e-04 0.1505975124
1644 P22626 HNRNPA2B1 0.7619731970 5.774953e-06 -0.1259800264
1645 Q13425 SNTB2 -0.9985660031 3.115714e-04 0.1547902954
1646 P50552 VASP 0.5519423779 2.128793e-02 0.2036752498
1647 Q96J88 EPSTI1 -1.1095042439 1.835069e-01 0.7971485090
1648 P42126 ECI1 1.0185534813 2.020110e-03 0.1516371828
1649 Q9HB40 SCPEP1 0.0897454152 8.330211e-01 -0.6404741507
1650 Q9HCL3 ZFP14 0.6803202071 6.676085e-03 0.5196648792
1651 Q96AX1 VPS33A -0.2167579337 1.449379e-01 -0.2664545546
1652 Q15165 PON2 0.2774137877 2.959670e-01 0.1786214258
1653 Q9NRF8 CTPS2 1.3238802508 1.837109e-16 0.1428261347
1654 Q9H9B4 SFXN1 0.2196153140 1.419957e-01 0.1536044680
1655 O43815 STRN 0.1048373712 7.259133e-01 -0.1134483301
1656 Q3KQZ1 SLC25A35 1.1664195057 4.317272e-07 0.6135109749
1657 Q9UJZ1 STOML2 0.0368973879 8.171965e-01 -0.2476196549
1658 Q99996 AKAP9 0.1948005093 4.232226e-01 -0.2443833248
1659 P18669 PGAM1 0.2028517603 3.849766e-01 0.2679061725
1660 Q13630 GFUS -0.4030045181 4.907970e-03 0.2119346831
1661 P12235 SLC25A4 1.3059959512 1.289144e-03 0.1232137170
1662 Q14766 LTBP1 0.9078201672 7.718248e-05 -0.3149054734
1663 P35579 MYH9 0.3064838495 6.147760e-01 0.2208384406
1664 Q9UGL1 KDM5B -0.5425211142 2.870172e-03 0.1939024144
1665 P07814 EPRS1 1.3991085717 6.673332e-11 0.1227043825
1666 Q9Y6K9 IKBKG -0.6062737695 2.527446e-06 0.5400156682
1667 P09972 ALDOC 1.9503624199 6.912356e-04 0.3560863340
1668 Q9Y265 RUVBL1 0.3032835184 4.325777e-02 -0.1487258718
1669 Q86TC9 MYPN 0.8167511169 1.148090e-01 0.2220605490
1670 O75051 PLXNA2 -0.6176603259 8.652638e-02 -0.1799037193
1671 P30533 LRPAP1 -1.1306558297 4.057262e-07 0.1967298835
1672 Q8NC56 LEMD2 -0.0046183220 9.824619e-01 -0.1402372840
1673 P23368 ME2 0.1709489761 4.827411e-01 0.1946472071
1674 Q9NRL2 BAZ1A -1.0786331149 9.534784e-04 0.2543600134
1675 Q13952 NFYC -0.2389293218 1.725348e-01 0.2361853690
1676 Q9BW92 TARS2 1.4429571358 2.152874e-08 -0.1210626053
1677 Q9BXP5 SRRT 0.5537577167 2.897458e-04 -0.1177464463
1678 O14980 XPO1 -0.1371049070 3.824226e-01 -0.1476165330
1679 Q04760 GLO1 0.2932020001 8.689470e-02 0.2606785320
1680 Q15436 SEC23A 0.6805391443 8.675127e-04 0.1399809919
1681 P04075 ALDOA 0.0437099893 9.203675e-01 0.1865845426
1682 Q9Y3L5 RAP2C -0.0492094416 7.889271e-01 0.1493853231
1683 Q9UBT2 UBA2 0.0243869844 9.111757e-01 -0.2555945521
1684 Q99943 AGPAT1 0.0330194316 8.025897e-01 0.2520398057
1685 Q96Q11 TRNT1 -0.0958705602 7.644507e-01 0.2996196471
1686 Q8IXS6 PALM2AKAP2 1.5083646100 2.554631e-04 0.1479163298
1687 Q6NUQ1 RINT1 0.2479042651 1.416423e-01 0.2057463484
1688 O14908 GIPC1 0.7507979068 1.175732e-06 0.2825310123
1689 P55011 SLC12A2 -0.1971249744 2.819238e-01 0.2640968158
1690 Q8N5B7 CERS5 -0.2107396217 6.479203e-01 0.1977423568
1691 Q9H936 SLC25A22 0.3061353463 4.664245e-01 0.3122123183
1692 Q9Y2J2 EPB41L3 0.0713132272 7.398659e-01 0.1232028947
1693 O96008 TOMM40 0.9213332719 7.199240e-09 0.1615035994
1694 Q06481 APLP2 -0.5376891342 4.303612e-03 0.1381457962
1695 O43681 GET3 -0.2007565862 1.422552e-01 0.1082411643
1696 P00742 F10 0.4890441414 1.182328e-01 -0.3288842935
1697 P04179 SOD2 0.2781151469 3.260615e-01 0.1236782127
1698 P12829 MYL4 0.3812090277 4.623616e-01 -0.2252215300
1699 O75955 FLOT1 -0.5223567371 3.467202e-02 0.1223331444
1700 O95816 BAG2 0.5760476370 6.416839e-03 -0.2449752601
1701 O95425 SVIL 0.2849438519 2.677598e-01 -0.1378927305
1702 P12883 MYH7 3.2002356649 2.374922e-06 0.1878757736
1703 Q9Y624 F11R -0.6698592368 7.290407e-02 -0.2704909154
1704 P16615 ATP2A2 1.3950531945 2.805068e-06 0.1065416788
1705 Q9UI12 ATP6V1H -0.5286497070 1.907817e-04 -0.2231393848
1706 Q8NCN5 PDPR 0.1245631168 6.835264e-01 0.1686627684
1707 P60174 TPI1 0.5239464535 2.235432e-01 0.2273542608
1708 P54802 NAGLU 0.1088198260 7.137069e-01 0.1815756870
1709 Q9NVH1 DNAJC11 0.2327038427 1.482114e-01 0.1263945529
1710 P33240 CSTF2 0.7411593546 1.436905e-04 -0.2019461981
1711 Q4KMQ2 ANO6 0.0869262523 5.858591e-01 0.1211254836
1712 P18754 RCC1 0.1984993716 5.687145e-01 0.1356243660
1713 P35612 ADD2 1.0966591721 3.731146e-02 0.3021874813
1714 P02144 MB 0.3409033194 6.394701e-01 -0.3342276775
1715 P45877 PPIC 0.1403106041 4.195817e-01 0.1508902709
1716 P14209 CD99 0.1339613296 5.522434e-01 0.8137557802
1717 Q13445 TMED1 0.7710553637 1.681322e-03 0.1385010702
1718 Q66K74 MAP1S -0.4471975949 3.154724e-03 0.1850543583
1719 Q6P587 FAHD1 -0.3824098055 1.904442e-03 -0.1377394502
1720 O60684 KPNA6 -0.3695764463 9.222340e-03 -0.4215543822
1721 Q9HAC7 SUGCT -1.0793388523 1.108564e-08 0.2098903285
1722 P60900 PSMA6 -0.3814378167 7.625722e-02 0.1124389846
1723 P10916 MYL2 0.7205282380 4.278901e-01 -0.3579173999
1724 P05091 ALDH2 -0.1774247001 3.132016e-01 0.1740427263
1725 P00558 PGK1 -0.1207563594 8.357532e-01 0.2193683417
1726 Q15629 TRAM1 0.4070980955 1.720433e-02 -0.1422236499
1727 P06730 EIF4E 0.0441172842 8.268671e-01 -0.1238886474
1728 Q96CW1 AP2M1 -0.1318980132 3.473382e-01 0.1100212785
1729 Q9H269 VPS16 -0.2413084532 9.153004e-02 -0.5201741173
1730 Q13427 PPIG -0.0262678567 9.151958e-01 -0.1613273299
1731 Q96CB9 NSUN4 0.9415160531 4.973727e-07 -0.1687411465
1732 Q5NDL2 EOGT 0.2822393347 4.797973e-02 -0.2654249140
1733 Q13564 NAE1 0.8003449594 1.029047e-08 0.4371709366
1734 Q9H223 EHD4 0.3609409286 1.149628e-01 0.3161051930
1735 P19823 ITIH2 -0.6444373128 7.828187e-01 0.2641095507
1736 Q96EC8 YIPF6 -0.1747482031 9.934305e-02 -0.2964064156
1737 O00567 NOP56 -0.2540248234 2.095424e-01 0.2449748418
1738 O95070 YIF1A 0.2854400715 6.551948e-02 -0.2071578184
1739 Q04656 ATP7A 0.3419538655 1.501427e-01 -0.3047021024
1740 Q96PE3 INPP4A -0.4470815633 1.016122e-04 0.1812734486
1741 O43813 LANCL1 0.5969387543 2.895836e-04 0.2028367121
1742 P55290 CDH13 0.1818396046 8.314755e-01 0.7374886596
1743 Q05086 UBE3A -0.5021721131 4.268154e-03 -0.3042980713
1744 P07339 CTSD 0.1030770325 7.056427e-01 0.1604490806
1745 P08238 HSP90AB1 0.0952591610 6.220550e-01 0.1199150173
1746 Q9Y5K8 ATP6V1D -0.4597088451 3.702169e-03 -0.1794847801
1747 P53621 COPA 0.0445635167 7.922981e-01 0.1198959270
1748 Q13433 SLC39A6 -0.3532648783 3.930349e-01 -0.3647429847
1749 Q9HDC9 APMAP -0.2734291892 4.693337e-01 0.1669020284
1750 P46977 STT3A 0.8200456788 1.230085e-02 0.2287939484
1751 Q9Y5K5 UCHL5 0.1053317596 5.846743e-01 0.1856459077
1752 Q9NZA1 CLIC5 0.3906525004 1.430895e-01 -0.2037149376
1753 Q6P4A7 SFXN4 1.2984385374 1.491799e-05 0.1680862376
1754 Q9BUN8 DERL1 0.2268389334 5.507804e-02 -0.4786288291
1755 Q6UXV4 APOOL -0.0735997758 6.890104e-01 0.1936065215
1756 Q8NB25 FAM184A -1.1543964258 1.603258e-03 0.2431381295
1757 P31948 STIP1 0.1941636203 2.222603e-01 0.1197831916
1758 Q8NI27 THOC2 0.3197363656 6.150198e-02 -0.1928366990
1759 P63104 YWHAZ -0.6623936141 1.156325e-04 -0.2896384659
1760 Q9BSF4 TIMM29 -0.5766783958 1.417637e-05 -0.1847857949
1761 P08590 MYL3 0.6491676322 2.020188e-01 -0.2268731958
1762 P48739 PITPNB -0.1627901348 3.913320e-01 0.3351063565
1763 Q01459 CTBS -0.6017499116 1.842871e-02 0.7262850014
1764 Q9H3K2 GHITM -0.5241435734 1.507280e-03 0.1193456952
1765 Q9GZY8 MFF 0.2661618043 2.479116e-02 -0.1856868209
1766 P49792 RANBP2 -0.2979140036 8.998002e-02 0.1411615606
1767 Q8WUD1 RAB2B 0.0272863409 8.351565e-01 0.1435746546
1768 Q12765 SCRN1 0.6442595169 1.342872e-02 -0.4121759213
1769 Q8NB12 SMYD1 1.9347224732 2.672598e-05 0.1950751068
1770 P0C7P0 CISD3 1.8293318918 2.316466e-10 -0.1774755759
1771 O15254 ACOX3 1.4282634458 3.580569e-06 -0.2440525252
1772 P36542 ATP5F1C 1.1684969164 1.389818e-03 0.1290881568
1773 P19440 GGT1 0.1182688532 8.687663e-01 -0.2845034110
1774 Q92508 PIEZO1 0.6087620640 4.257620e-02 0.2868523980
1775 O00232 PSMD12 -0.2712867753 3.982575e-02 -0.1521050477
1776 Q15155 NOMO1 0.1704716095 4.735078e-01 0.1508234778
1777 Q9UHD8 SEPTIN9 0.4755562779 3.322623e-03 0.2021339246
1778 Q5JPE7 NOMO2 0.2079791567 4.531615e-01 0.1502564030
1779 O75879 GATB 0.2279772762 1.554719e-01 0.2424868192
1780 Q9Y490 TLN1 0.3420736536 8.924860e-02 0.1045821854
1781 Q96KG9 SCYL1 -0.2893014229 3.637259e-02 -0.5027216185
1782 Q13505 MTX1 -0.1467346670 6.199701e-01 -0.1676507132
1783 Q9UJS0 SLC25A13 0.1982585679 6.345327e-02 0.1540476330
1784 Q86TB3 ALPK2 1.1941536798 1.404986e-05 -0.3214679156
1785 Q2M2I8 AAK1 -0.4396088834 1.902638e-02 -0.2352245268
1786 O00468 AGRN -0.8129678401 1.587084e-02 0.2760268696
1787 Q96FW1 OTUB1 -0.4010101437 5.500048e-04 0.5918018898
1788 Q13185 CBX3 0.5065139414 5.001146e-03 -0.5086292319
1789 P68400 CSNK2A1 0.3173211773 1.966664e-02 -0.1264495797
1790 P28331 NDUFS1 0.5373744935 1.844769e-03 0.1013530396
1791 Q9Y263 PLAA 0.2136937563 7.739730e-02 -0.2299422577
1792 P00167 CYB5A 1.6098182159 3.465401e-06 0.1600876037
1793 Q9NVH6 TMLHE 0.6793260045 3.633019e-03 0.1448143904
1794 P20020 ATP2B1 -0.7931718607 4.120125e-04 -0.1459837821
1795 Q9Y4L1 HYOU1 0.0117236366 9.807059e-01 0.1708269618
1796 P26196 DDX6 0.1186047278 5.234808e-01 -0.1106735179
1797 P14923 JUP -0.6364280671 1.506576e-03 -0.1393551959
1798 P25205 MCM3 2.4623633421 1.867494e-13 -0.2332978096
1799 Q9H3N1 TMX1 -0.4253745548 2.912518e-01 0.1911236098
1800 O43759 SYNGR1 0.4904738733 6.795980e-02 0.3656204165
1801 O60271 SPAG9 -0.3933658419 3.835940e-03 0.1855972361
1802 Q96GS4 BORCS6 -0.7090553563 2.163665e-04 -0.5961135139
1803 Q5SRE5 NUP188 0.3092479704 1.453906e-01 -0.3925170994
1804 P42224 STAT1 -2.0579704677 7.148119e-16 0.5855252691
1805 Q92820 GGH 0.4160082923 2.192069e-01 0.1064003350
1806 Q07866 KLC1 0.0718530160 5.387119e-01 0.1318888957
1807 Q16513 PKN2 0.9101622622 6.846336e-05 -0.3903692553
1808 Q9NTI5 PDS5B 0.3685288435 4.091455e-02 -0.1533700029
1809 P23327 HRC 0.5428981226 1.702822e-01 0.2387106959
1810 Q15631 TSN -0.2364457264 5.589455e-02 0.2206874894
1811 Q6P1A2 LPCAT3 -0.3820973402 7.840920e-02 0.2277853536
1812 O00151 PDLIM1 -0.4085455973 1.691772e-01 0.1937722354
1813 Q9UHQ4 BCAP29 1.3692174226 2.169737e-05 0.1988457745
1814 P48729 CSNK1A1 -0.3718222498 3.449183e-04 -0.1098624407
1815 P09211 GSTP1 -1.2398485588 1.562978e-04 0.1386420303
1816 P62136 PPP1CA -0.6013982668 2.374922e-06 -0.1166498631
1817 P50502 ST13 -0.3448671946 6.254709e-02 0.1402020249
1818 Q08257 CRYZ -0.0208235580 9.652077e-01 0.2084939460
1819 Q7L523 RRAGA -0.9521859873 8.455097e-09 0.1059867484
1820 P22061 PCMT1 0.0493894149 7.817566e-01 -0.1379744633
1821 Q32MK0 MYLK3 0.7087779413 6.127695e-02 0.2027328807
1822 Q8NFH4 NUP37 0.1458760466 5.111842e-01 -0.2263056092
1823 O94776 MTA2 -1.2162968176 3.421653e-06 -0.1556871183
1824 Q5SYE7 NHSL1 1.0705508482 3.484130e-04 0.2624877482
1825 Q8N8Q8 COX18 -0.0110891346 9.536399e-01 0.5482295030
1826 P09486 SPARC 0.1568362773 7.691643e-01 -0.3398549778
1827 Q9BRX8 PRXL2A 0.2092975969 4.171057e-01 0.1059117284
1828 Q16778 H2BC21 -1.4495079785 3.380343e-09 0.1865763781
1829 P62191 PSMC1 0.0400134349 7.914979e-01 0.1104266196
1830 P56134 ATP5MF 0.0823190520 7.345604e-01 -0.1175481021
1831 P51553 IDH3G 0.4376905600 6.857067e-03 0.1406275506
1832 Q6UWP7 LCLAT1 1.2097435583 9.233786e-06 -0.1100540659
1833 Q9UKK6 NXT1 0.5846142978 9.009009e-03 0.1996727921
1834 P08174 CD55 -0.8067393884 4.413626e-02 -0.3830711095
1835 P36404 ARL2 0.4760897507 4.029220e-02 0.1497891845
1836 P40123 CAP2 1.1655884901 4.626400e-05 0.2127646086
1837 Q15149 PLEC 0.3224732115 1.896376e-01 0.0989970306
1838 P27338 MAOB -1.3085970453 1.185109e-01 -0.2416044788
1839 P11055 MYH3 0.8343898183 1.790471e-01 -0.3289073428
1840 Q9UMS0 NFU1 -0.1518704934 5.904522e-01 0.5362827661
1841 Q9NZJ6 COQ3 1.1216940835 1.059948e-04 -0.1937537190
1842 P21796 VDAC1 0.1436004662 3.942572e-01 0.1130945858
1843 P06732 CKM 0.6134077660 4.766527e-01 0.2743177664
1844 Q8IXI2 RHOT1 0.8557003235 9.860472e-07 -0.1023378975
1845 Q9UQ80 PA2G4 -0.7709128371 1.855568e-08 0.1674143768
1846 Q9H9G7 AGO3 0.0782431877 6.981589e-01 0.2266581825
1847 P17050 NAGA -0.2319044352 4.672553e-01 0.1456591584
1848 Q9BU23 LMF2 -1.5700660393 3.711224e-08 0.1656514288
1849 O75112 LDB3 2.7434689196 7.381874e-07 0.1573491429
1850 Q6ZP82 CCDC141 1.5360523458 2.019713e-03 -0.1081806014
1851 Q14141 SEPTIN6 0.3494888553 1.890797e-01 0.3007788675
1852 P24666 ACP1 0.1039417074 4.446857e-01 0.1806922599
1853 O00764 PDXK -0.5187015367 1.260691e-02 0.1675754927
1854 O75781 PALM 0.7913553309 2.824205e-06 0.1608435877
1855 O00629 KPNA4 -0.1831928559 1.137567e-01 -0.1624602228
1856 P53999 SUB1 -0.2134022058 2.946914e-01 0.2110096754
1857 Q9BUQ8 DDX23 -0.0831184730 7.359313e-01 -0.1172680589
1858 O43292 GPAA1 -0.4578929246 6.926732e-04 0.1427424435
1859 P07203 GPX1 -2.4590465803 4.844657e-13 0.1554968850
1860 P38117 ETFB 0.5427571027 3.114159e-02 0.1152187935
1861 Q13683 ITGA7 0.2708923890 5.313725e-01 0.1341858302
1862 Q7Z7H8 MRPL10 -0.3603634488 2.478305e-03 -0.2120833022
1863 O75844 ZMPSTE24 0.0888249323 8.347974e-01 0.1786406642
1864 P17858 PFKL -0.0042978206 9.902724e-01 0.2571098478
1865 Q7L0Y3 TRMT10C -0.1881399775 3.640171e-01 0.1291873526
1866 P98172 EFNB1 -1.9085143771 4.814741e-09 -0.3272065357
1867 P38646 HSPA9 0.7979750611 3.230682e-06 0.1168814392
1868 P49411 TUFM -0.3614799938 5.557599e-04 0.1108361099
1869 Q8IXT5 RBM12B 0.5067110236 2.616229e-02 0.1384347078
1870 Q8NCW5 NAXE 0.2580156677 1.217783e-01 -0.1891713554
1871 Q14896 MYBPC3 0.5923821171 1.348475e-01 0.1551579680
1872 Q6PK18 OGFOD3 0.8702332461 4.996088e-08 0.1939043677
1873 Q9NRL3 STRN4 0.3398639974 2.990451e-03 0.1413990622
1874 O75165 DNAJC13 0.7807099953 2.589505e-09 -0.1258222035
1875 Q9UJA5 TRMT6 -0.1525527130 3.176235e-01 -0.1781832359
1876 C9JTQ0 ANKRD63 0.7409783790 5.179543e-01 -0.4181034357
1877 Q9HBH1 PDF 0.4324040400 1.913444e-01 -0.3972969266
1878 P09651 HNRNPA1 0.8402598523 2.681422e-05 -0.1025116264
1879 Q93034 CUL5 0.1618714903 3.406833e-01 -0.1189350733
1880 P54577 YARS1 0.4680289055 8.632363e-03 0.1600657958
1881 O75487 GPC4 -0.9927054445 9.088184e-03 0.3644860585
1882 Q9P2K5 MYEF2 0.5766910513 3.057090e-03 -0.1733205454
1883 P23381 WARS1 0.2262799839 3.925141e-01 -0.3338646105
1884 P78310 CXADR -0.0109802143 9.623291e-01 -0.2296435722
1885 Q13217 DNAJC3 0.6080622664 5.599550e-02 0.2380869581
1886 P04040 CAT 0.6575400108 1.967081e-01 -0.3228400161
1887 Q9UHL4 DPP7 0.3597153229 5.185833e-01 0.1405542089
1888 Q9UGP8 SEC63 0.5837381944 9.973318e-05 0.1356121218
1889 P14854 COX6B1 -0.1059131964 7.451698e-01 -0.2309149387
1890 Q9Y3D3 MRPS16 -0.0287521425 8.917191e-01 -0.2270881915
1891 P61978 HNRNPK 0.1364059191 2.551803e-01 -0.0908786821
1892 P15531 NME1 -0.2613820498 4.497980e-01 0.1964047121
1893 O75323 NIPSNAP2 0.7843169924 1.550574e-02 0.1164590731
1894 P15924 DSP -0.2366972975 3.077717e-01 -0.2221418710
1895 Q9HAB3 SLC52A2 0.3501628861 2.070068e-01 0.1019734385
1896 Q13190 STX5 -0.9383245202 3.310862e-07 -0.1438827917
1897 Q9Y4P3 TBL2 0.9026931871 2.374922e-06 -0.1376909006
1898 Q14651 PLS1 0.2091548574 4.352572e-01 -0.2391865419
1899 Q8TCS8 PNPT1 0.2014867737 3.051769e-01 0.1246305850
1900 Q02978 SLC25A11 0.8197128328 3.226581e-03 0.1253233305
1901 Q16881 TXNRD1 -1.7811172154 8.055294e-05 0.5291243342
1902 O14683 TP53I11 -1.4212290760 1.116181e-03 0.1794061749
1903 Q969X5 ERGIC1 -0.0185468404 9.577110e-01 0.1341115999
1904 Q15833 STXBP2 -0.3229616767 3.022883e-01 -0.2935734855
1905 P10619 CTSA -0.1007956107 6.370888e-01 0.1232787774
1906 P52815 MRPL12 1.2502905930 5.432475e-05 -0.3479027395
1907 Q9Y2H6 FNDC3A -0.1116559628 5.327590e-01 -0.4244074996
1908 P10155 RO60 0.0543694078 8.344448e-01 0.1438558273
1909 P43034 PAFAH1B1 0.1929284581 4.288570e-01 -0.1716659061
1910 P09429 HMGB1 0.4656724164 3.570169e-02 0.1732072375
1911 Q13813 SPTAN1 0.3142588362 3.137613e-01 0.0911141711
1912 O43464 HTRA2 -0.4377286721 9.427037e-05 -0.1555959272
1913 P35613 BSG -0.1443275679 4.754237e-01 0.1463125698
1914 Q8IXM6 NRM 1.6791260262 6.276217e-09 -0.1277078100
1915 Q6VY07 PACS1 -0.2190860038 4.020375e-01 0.2111877176
1916 Q9NR12 PDLIM7 -0.0429888691 9.221062e-01 -0.3509102066
1917 O15078 CEP290 0.6782119363 2.159324e-03 0.4736180211
1918 Q9BRJ7 NUDT16L1 0.3122016247 1.501522e-01 -0.2906977060
1919 Q9BZF9 UACA 0.3040818225 3.810870e-01 0.1587803118
1920 O60825 PFKFB2 -0.6979328827 1.144153e-02 0.2827424002
1921 Q13423 NNT 0.7812013239 6.762288e-03 0.1346303030
1922 Q1KMD3 HNRNPUL2 0.1163294045 4.825500e-01 -0.1327156417
1923 Q15800 MSMO1 0.5468242144 9.635216e-02 -0.1526145948
1924 Q6P1Q0 LETMD1 0.6995173166 6.017717e-05 0.1546073095
1925 P33897 ABCD1 0.6290223935 4.198877e-06 0.1528123888
1926 Q12955 ANK3 -0.0509586450 8.864972e-01 -0.0969674495
1927 P46199 MTIF2 0.1096824103 4.585699e-01 0.1297635336
1928 P23588 EIF4B 0.3770311203 1.557476e-02 0.1195975287
1929 O95622 ADCY5 1.1975133863 3.300409e-05 -0.1419630652
1930 P06733 ENO1 0.5422332635 1.738513e-01 0.1826309791
1931 Q9NTJ4 MAN2C1 0.0033617407 9.870447e-01 0.1393937256
1932 P50454 SERPINH1 0.0839964853 8.162662e-01 0.1471579924
1933 Q96I25 RBM17 0.0296826351 8.189223e-01 -0.2051732977
1934 Q9Y394 DHRS7 -0.3713217263 2.899647e-01 -0.1402833892
1935 O95865 DDAH2 2.1602406748 9.407488e-10 0.1720986788
1936 Q8NFH3 NUP43 0.3934607468 1.650592e-02 0.1091842804
1937 Q86U28 ISCA2 0.7101169214 1.344176e-02 -0.3145349692
1938 O43306 ADCY6 0.1854319436 5.083174e-01 -0.1829436373
1939 Q8IW45 NAXD -0.8358224024 5.485080e-07 0.1620047804
1940 Q9HAB8 PPCS 0.0848111115 6.423964e-01 0.2956679206
1941 Q53H12 AGK 0.9499337765 5.633987e-07 0.1035594132
1942 Q9Y4W2 LAS1L 0.4829859012 4.905683e-02 -0.1389552255
1943 Q96S52 PIGS -0.0010698844 9.955733e-01 0.1635104108
1944 Q96I99 SUCLG2 0.5196720525 6.050381e-02 0.0926078408
1945 P43686 PSMC4 -0.0325124396 7.560025e-01 -0.1469129728
1946 Q7Z6Z7 HUWE1 -0.0639333870 7.738442e-01 0.1665853652
1947 P51687 SUOX 1.3181201409 1.261956e-08 -0.1012366081
1948 P84103 SRSF3 1.2891684690 6.009634e-05 -0.0919919405
1949 P21399 ACO1 0.1054063310 6.197900e-01 0.2428422205
1950 Q32MZ4 LRRFIP1 0.3632510580 1.125297e-01 -0.1873734274
1951 Q15811 ITSN1 -0.0200925973 9.439519e-01 0.1335478206
1952 P23284 PPIB 0.4016368648 1.902491e-01 0.1240278652
1953 Q9BT09 CNPY3 0.1426578740 4.456442e-01 -0.1369132601
1954 P36871 PGM1 0.7071756094 1.389818e-03 0.1980879304
1955 P11117 ACP2 0.0440008418 8.746155e-01 -0.0920412487
1956 Q99700 ATXN2 -0.0249898086 9.112628e-01 0.2525084456
1957 P62333 PSMC6 0.0414103976 8.718443e-01 0.1092616396
1958 O00159 MYO1C 0.5776184258 9.362778e-04 0.1195647718
1959 P11279 LAMP1 -0.6347087295 7.318359e-02 0.1754433704
1960 P82664 MRPS10 0.0300941178 8.638571e-01 -0.1603465862
1961 P21926 CD9 -1.1353037654 6.391773e-03 0.4607441303
1962 Q9NR19 ACSS2 0.4434773080 3.407810e-02 0.3602161255
1963 Q9HAV7 GRPEL1 -0.2872256298 1.767325e-01 -0.2937040729
1964 P60981 DSTN 0.0613880656 8.155761e-01 0.1293255070
1965 Q9UKX2 MYH2 1.5995453403 2.936946e-03 0.1228670487
1966 Q7L775 EPM2AIP1 -0.4468333524 4.801878e-02 -0.2945009993
1967 Q5TC12 ATPAF1 0.3745649103 9.720010e-02 0.1273674588
1968 Q14696 MESD 0.5874278948 3.633019e-03 0.1601022524
1969 P24390 KDELR1 0.3645262940 3.847837e-02 -0.6319949280
1970 P15259 PGAM2 1.3221396063 7.599926e-03 0.1491572499
1971 P46937 YAP1 -0.6938726648 3.686012e-05 -0.1672168492
1972 Q15738 NSDHL 0.2802517274 3.302512e-02 0.1139328640
1973 P29692 EEF1D -0.5515698350 4.801212e-06 -0.1942462621
1974 Q13492 PICALM 0.1757807814 3.326360e-01 -0.1330187061
1975 Q9BV79 MECR -0.2169496192 1.244770e-01 0.2060868424
1976 P04626 ERBB2 1.5185983895 1.391522e-06 -0.1160366021
1977 Q7KZF4 SND1 0.5709247746 4.507875e-04 -0.0944147087
1978 P13591 NCAM1 1.0425527917 1.475188e-04 0.1359207349
1979 Q9H4G4 GLIPR2 -0.8726009629 1.435338e-01 -0.1377189249
1980 Q9BW91 NUDT9 0.5778246744 2.560287e-03 0.0939589999
1981 P35914 HMGCL -0.7507578460 1.150621e-05 0.1043407372
1982 P36551 CPOX -0.5409078890 4.832631e-03 -0.1052286710
1983 Q13330 MTA1 0.4177181242 6.967793e-03 -0.1539773030
1984 Q5T0D9 TPRG1L 0.0619930937 7.863513e-01 0.1337896782
1985 Q9H6K4 OPA3 1.0512981873 5.119571e-07 -0.2536091609
1986 P45954 ACADSB 0.0465525644 8.530599e-01 0.1093543052
1987 Q96MU7 YTHDC1 0.0953811645 6.055396e-01 0.1431320158
1988 P49915 GMPS 0.3891110973 4.962040e-03 0.1687013129
1989 Q9UI47 CTNNA3 1.6839019804 9.180409e-04 0.1572445637
1990 Q93009 USP7 -0.1181368389 3.942116e-01 0.0848902434
1991 P11182 DBT 0.1493468639 2.903078e-01 0.1053534927
1992 P61619 SEC61A1 -0.3498077658 2.947810e-01 -0.1798585110
1993 Q96HP0 DOCK6 0.1986534823 6.773818e-01 -0.1852202414
1994 Q9NP90 RAB9B 2.3479670371 5.184398e-08 -0.2282349511
1995 Q9UL54 TAOK2 0.8273022724 1.585060e-09 -0.1331274024
1996 P82909 MRPS36 0.6037590805 3.134948e-02 -0.1503714294
1997 Q9BYV6 TRIM55 -0.0249223865 9.277871e-01 -0.0941274403
1998 O75396 SEC22B 0.2198585093 1.556393e-01 -0.1582100924
1999 Q53GS9 USP39 0.1950545675 1.074006e-02 -0.1223646655
2000 Q9UM00 TMCO1 -0.1557144385 2.512859e-01 -0.2788674167
2001 P10644 PRKAR1A -0.0500805377 8.882699e-01 -0.2009798037
2002 Q9UGV2 NDRG3 1.0968856862 2.489318e-06 -0.1642863515
2003 Q5JRA6 MIA3 0.4869522066 5.922553e-03 0.2517651870
2004 P82675 MRPS5 0.1733821004 2.569455e-01 -0.1189895730
2005 Q9UQB3 CTNND2 0.5472299676 4.133040e-02 -0.1132828115
2006 Q8NBU5 ATAD1 0.2996948430 1.737459e-01 0.1344889029
2007 P08582 MELTF -0.8051590739 6.821040e-02 0.2632308677
2008 P36543 ATP6V1E1 -1.0903026949 1.234720e-11 -0.2839601305
2009 Q06323 PSME1 0.0677612368 7.809287e-01 -0.1809043530
2010 Q9P0L0 VAPA -0.3390880755 5.894954e-02 -0.1079442040
2011 Q6P1X6 C8orf82 0.6919838723 7.940349e-03 -0.0919210459
2012 P10606 COX5B 0.1136845784 7.808695e-01 -0.1385477506
2013 O75976 CPD -0.3720645013 1.305032e-01 0.1402636759
2014 Q15393 SF3B3 0.6033894698 3.130775e-04 -0.1082147945
2015 P78371 CCT2 0.1387950818 6.615389e-01 0.1060104999
2016 Q9BSJ5 C17orf80 -1.9094758017 1.826841e-06 -0.3300467973
2017 O95298 NDUFC2 0.2171100335 2.916878e-01 -0.2176380759
2018 Q6UY14 ADAMTSL4 0.2640725434 3.106133e-01 0.5124778155
2019 Q13557 CAMK2D 0.7896298789 8.483366e-05 0.1396464367
2020 Q9Y4F3 MARF1 -0.6213787707 1.966890e-05 0.1849873854
2021 Q02809 PLOD1 0.5021732260 4.207209e-02 -0.1161368344
2022 Q8TB37 NUBPL 0.2889109415 1.650630e-01 0.1841135011
2023 P12694 BCKDHA 0.0418078579 9.417757e-01 0.1132479572
2024 Q9BUR5 APOO 0.8972709740 4.653243e-03 -0.1097208441
2025 Q9H9J2 MRPL44 -0.6020990218 5.948296e-09 -0.2216553149
2026 Q96S66 CLCC1 0.4053448262 1.791996e-02 0.1348035251
2027 Q9NWB6 ARGLU1 -0.3034139972 6.762886e-02 0.2356284579
2028 Q8WWV3 RTN4IP1 1.1387567419 1.291165e-07 0.1552915531
2029 P48147 PREP 0.5312112286 2.689724e-03 0.2229599558
2030 Q16576 RBBP7 0.4930926376 2.598395e-02 -0.1129805033
2031 O95831 AIFM1 0.3042610253 1.506253e-01 0.1175729384
2032 Q9BTC0 DIDO1 0.0081538646 9.673552e-01 -0.5603799007
2033 P33527 ABCC1 -0.5059668958 3.604825e-02 0.1192798867
2034 Q7L9L4 MOB1B -1.0788648618 3.975851e-07 0.2850250352
2035 P48556 PSMD8 -0.6539189031 2.549062e-07 -0.1177878913
2036 Q96RQ3 MCCC1 0.5068670420 2.622499e-04 -0.1306215778
2037 Q9NWM8 FKBP14 0.9259873757 1.926029e-03 -0.3068203340
2038 O95159 ZFPL1 -0.3443103880 6.845974e-03 -0.1089420401
2039 Q9NQE9 HINT3 0.0146610053 9.466218e-01 -0.2140358593
2040 Q00765 REEP5 -0.0498913897 8.026646e-01 0.1066922979
2041 P13667 PDIA4 0.1867214309 6.356035e-01 0.1173837438
2042 P23258 TUBG1 0.3404453465 5.861478e-03 0.1281586003
2043 Q96AN5 TMEM143 0.9747646338 3.461372e-03 -0.1559450159
2044 O60256 PRPSAP2 -1.0903066790 1.788167e-10 -0.1024336555
2045 Q9NTJ5 SACM1L -0.2267662753 3.417828e-01 -0.1611255677
2046 Q5JTZ9 AARS2 1.0525817491 1.371412e-05 0.1072285522
2047 P62820 RAB1A -0.7960844766 1.573876e-07 -0.0970143479
2048 P49748 ACADVL -0.5215803449 4.066065e-04 0.0980933538
2049 Q2TAA5 ALG11 0.0794104546 7.969870e-01 -0.1054766979
2050 P49753 ACOT2 -0.1800431002 7.401664e-01 0.1185292661
2051 Q92499 DDX1 0.8726358372 3.619793e-07 -0.0837789331
2052 O75643 SNRNP200 0.0243711566 8.839931e-01 0.0791359883
2053 Q9P0S9 TMEM14C -0.3607514130 2.138033e-01 -0.1178194013
2054 Q14192 FHL2 1.5223476866 1.765607e-02 -0.1693795768
2055 O60664 PLIN3 -0.3496687575 1.273580e-01 0.1613657814
2056 P82673 MRPS35 0.6611793127 4.555276e-06 -0.0989629001
2057 Q9Y512 SAMM50 0.1916689996 1.419957e-01 0.0902401783
2058 O43747 AP1G1 0.0283419493 9.060774e-01 0.2260558350
2059 Q9BYD6 MRPL1 0.4579710660 8.064139e-02 -0.1457402759
2060 Q9NZ01 TECR 0.4524086470 3.547010e-03 0.0966267844
2061 P00492 HPRT1 0.1575700639 7.224271e-01 0.3826193809
2062 O60669 SLC16A7 1.6263558051 9.193574e-07 -0.2439902363
2063 Q9P0T7 TMEM9 0.2286258113 2.548708e-01 -0.2897704100
2064 O60331 PIP5K1C -0.3896952797 4.796960e-02 0.1213932177
2065 Q99442 SEC62 0.0476309248 8.008723e-01 -0.1253172696
2066 Q9NZ32 ACTR10 0.0855859427 6.892018e-01 -0.2943213697
2067 Q8N0X4 CLYBL 0.3804443378 4.146781e-01 0.3756555127
2068 Q9H6Z4 RANBP3 -0.0074115872 9.631476e-01 0.2582655819
2069 Q9NTG7 SIRT3 -0.2571646352 3.838222e-01 0.2295703517
2070 P26599 PTBP1 -0.2950528569 4.211937e-01 -0.1032980210
2071 Q9UKP3 ITGB1BP2 2.0604218697 2.109661e-05 -0.2791393242
2072 P17980 PSMC3 0.2273719907 2.332383e-02 0.0926776020
2073 Q9NVS2 MRPS18A -0.0402082025 8.031348e-01 -0.1106006243
2074 Q02338 BDH1 2.1157291743 5.303489e-04 0.0995037586
2075 Q9H6R4 NOL6 -0.4310167487 1.700926e-01 -0.2318329234
2076 Q53GG5 PDLIM3 -0.8674231586 2.768987e-01 0.1751096875
2077 P30049 ATP5F1D 0.8888212343 3.257062e-03 -0.1321410744
2078 Q9NRW1 RAB6B 0.6111505322 7.677371e-03 -0.1501626685
2079 P11387 TOP1 -0.3960226533 1.712180e-02 -0.0999382249
2080 P26358 DNMT1 1.0374283384 4.595571e-10 0.1961702509
2081 Q96AQ8 MCUR1 0.0386033469 8.367774e-01 -0.2665467709
2082 P53990 IST1 -0.3967481091 2.203305e-03 -0.4385883218
2083 Q15084 PDIA6 -0.0316269750 9.313407e-01 0.1304443104
2084 P61006 RAB8A 0.5204945315 6.672035e-03 -0.1065776955
2085 P16671 CD36 1.3086566808 6.254709e-02 -0.1614489475
2086 O75874 IDH1 0.7789141704 2.457396e-03 -0.2719364230
2087 Q9NR77 PXMP2 0.7838406018 8.064319e-03 -0.3388657821
2088 P30153 PPP2R1A -0.0026459700 9.890591e-01 0.0981272779
2089 Q8N697 SLC15A4 0.2649307754 3.593882e-01 0.2328756144
2090 Q9Y371 SH3GLB1 -0.5369464880 4.355728e-02 -0.2799289032
2091 Q16270 IGFBP7 -0.0553297749 8.820208e-01 -0.1735731130
2092 P06753 TPM3 0.1100660054 8.361777e-01 -0.4929113011
2093 P13674 P4HA1 0.4657140377 2.025001e-01 -0.0922032534
2094 P48637 GSS -0.1895269333 1.869396e-01 -0.2779636141
2095 O43824 GTPBP6 0.4602950667 1.395504e-03 -0.2734504237
2096 P17661 DES 1.6751198127 5.708764e-02 0.4497415915
2097 Q7LGA3 HS2ST1 -0.3940804973 9.973634e-02 -0.1073078980
2098 Q9UI14 RABAC1 -0.2886104805 1.764840e-01 -0.1876504937
2099 P48730 CSNK1D -0.4763333110 7.179966e-04 0.2062944598
2100 Q86VM9 ZC3H18 0.0016572135 9.932779e-01 -0.1898250821
2101 Q7KZ85 SUPT6H -0.2880921875 1.533015e-01 -0.1685498276
2102 O60313 OPA1 0.2543018841 9.554793e-02 0.1044799417
2103 P49368 CCT3 0.4268448363 4.046655e-05 0.0999937434
2104 Q9NSD9 FARSB 0.9403096582 5.430703e-08 0.0935948268
2105 Q15102 PAFAH1B3 1.2245017608 9.140099e-08 -0.3013653463
2106 P53004 BLVRA 0.4111088016 1.230085e-02 0.2822536255
2107 Q96KN1 LRATD2 -0.2446503381 4.592222e-01 -0.3061198829
2108 Q8NE79 BVES 1.4326553411 7.542194e-06 0.0752190673
2109 P29536 LMOD1 3.1782789254 8.557605e-10 0.1644296131
2110 P50897 PPT1 0.9741334443 5.476262e-03 -0.1573011749
2111 Q16186 ADRM1 -0.7835078963 3.213693e-09 0.2551237886
2112 P50579 METAP2 -0.0599410000 7.424054e-01 0.3789248124
2113 Q02218 OGDH 0.1151495497 4.763414e-01 0.0946360809
2114 Q92796 DLG3 0.0836581500 7.209849e-01 0.1547593964
2115 P09874 PARP1 1.2169672572 2.774678e-08 0.1457073318
2116 Q96ND0 FAM210A 0.7832647817 1.615588e-03 -0.1786974852
2117 P42704 LRPPRC -0.5276565080 4.153601e-03 -0.1012872358
2118 Q93050 ATP6V0A1 -0.9783735854 1.119784e-03 0.1174575184
2119 P11310 ACADM 0.3200875712 3.319724e-01 0.1087991394
2120 P17612 PRKACA -0.4313467858 8.929479e-02 0.1294518467
2121 Q96JM3 CHAMP1 -0.2339891329 1.856538e-01 -0.1804230458
2122 Q96A26 FAM162A 0.4943920832 4.654980e-01 -0.1753460633
2123 O60229 KALRN 0.0660899933 8.703066e-01 0.6861820167
2124 P51795 CLCN5 -1.1586569450 4.289188e-02 0.1918283846
2125 P58876 H2BC5 -1.2798282928 2.306805e-05 0.1414397274
2126 P45880 VDAC2 0.1819745631 3.549004e-01 0.0846556240
2127 Q92831 KAT2B -1.4585588026 1.205558e-07 -0.2659856053
2128 Q86U86 PBRM1 0.1982857723 1.405046e-01 -0.2355238688
2129 Q13616 CUL1 -0.0929825149 5.173780e-01 -0.1159312603
2130 P12814 ACTN1 -0.4309626504 3.900074e-01 0.2095158169
2131 Q92968 PEX13 0.4610680112 2.732571e-03 -0.4157903448
2132 P38159 RBMX 0.8503418139 6.771555e-05 -0.1113749380
2133 Q9BX68 HINT2 0.3337722805 1.996118e-01 0.1161351290
2134 Q8TEQ6 GEMIN5 0.3169870947 5.899150e-02 -0.2726417501
2135 Q96CN7 ISOC1 0.6062568892 5.940723e-02 0.1210246679
2136 P15311 EZR 0.7365071191 1.448667e-05 0.0848442530
2137 Q9HBH5 RDH14 0.0640385155 8.270659e-01 0.1034871730
2138 P13533 MYH6 2.6154693930 7.116697e-09 0.2476201453
2139 Q9Y285 FARSA 0.2534751718 2.042847e-01 -0.1575405030
2140 P51452 DUSP3 0.1740663875 5.069760e-01 -0.2838945881
2141 Q6DKK2 TTC19 -0.1962182345 1.964601e-01 -0.2687302665
2142 P30837 ALDH1B1 -0.8517062256 2.544079e-02 0.1980954870
2143 P14672 SLC2A4 1.6302501747 9.199969e-04 -0.1693895431
2144 Q9Y6B6 SAR1B 0.5346682497 1.691695e-04 -0.1423709405
2145 Q9UHQ9 CYB5R1 0.5458996455 1.670314e-02 0.1023200639
2146 Q13796 SHROOM2 -0.5983633213 9.919486e-02 -0.2184100347
2147 O60662 KLHL41 0.6103980614 1.342304e-01 0.1576033040
2148 Q08357 SLC20A2 1.3158173086 4.610660e-07 0.1632916359
2149 Q8NBM8 PCYOX1L -1.1223898034 6.889023e-07 0.1021725140
2150 Q8IV08 PLD3 0.2320951973 2.799846e-01 0.1057716482
2151 Q12906 ILF3 0.1970056909 2.071025e-01 -0.0739419192
2152 P13073 COX4I1 0.2390963512 4.112933e-01 -0.0941046311
2153 Q709C8 VPS13C -0.7426917078 9.377918e-05 0.5567733277
2154 P51649 ALDH5A1 0.1085656600 6.413752e-01 0.1188716514
2155 Q07021 C1QBP 1.0392634810 4.251062e-08 0.1341548659
2156 O15269 SPTLC1 -0.6254079075 7.575681e-04 -0.1014993198
2157 Q9Y6C9 MTCH2 0.6885775260 2.562630e-05 0.0920632675
2158 Q15031 LARS2 0.1095651629 6.535154e-01 0.0830265367
2159 P18084 ITGB5 0.2789205655 4.714806e-01 0.1178529959
2160 P11277 SPTB 0.3071476653 3.158852e-01 0.1087674664
2161 P33991 MCM4 0.5335065626 1.011400e-01 0.2768044646
2162 Q9H6U6 BCAS3 0.5287596931 3.371953e-02 -0.1314082211
2163 Q6UB35 MTHFD1L -0.3169301398 1.984854e-01 -0.1219872828
2164 Q5HYK3 COQ5 0.2405829159 2.354522e-01 0.1056491090
2165 Q9NRP0 OSTC 0.5667623757 1.131441e-02 -0.1283539466
2166 P21281 ATP6V1B2 -0.4857983051 2.239842e-02 -0.1003376983
2167 Q9NZE8 MRPL35 0.9341455701 3.583120e-05 -0.1057187487
2168 O15344 MID1 0.5082765108 1.113637e-01 -0.2140228002
2169 Q9H8Y8 GORASP2 0.5253634640 4.746911e-04 0.1189427241
2170 Q9HCM2 PLXNA4 1.6632168204 6.838493e-04 -0.2088961218
2171 O75746 SLC25A12 2.2971653888 2.992524e-07 0.0962979309
2172 Q9Y3E1 HDGFL3 -0.4240065194 1.567336e-03 0.1094022386
2173 P27695 APEX1 0.8043768497 6.101284e-09 0.1462977043
2174 Q6NXT6 TAPT1 -0.9337846330 2.414441e-09 0.5165688842
2175 P27797 CALR 0.4182562575 1.423336e-01 0.1188448055
2176 O43776 NARS1 0.5274102662 7.701333e-04 0.1329451073
2177 Q9NXA8 SIRT5 -0.1908772118 2.928658e-01 0.0963912099
2178 P26583 HMGB2 0.7445039339 1.273074e-01 0.1398682501
2179 P26639 TARS1 0.2337347050 1.546895e-01 0.0859174106
2180 Q8IX12 CCAR1 -0.1417217972 3.791233e-01 0.0973916468
2181 P13797 PLS3 -0.6275368199 1.528067e-01 0.3294577858
2182 P49959 MRE11 0.1021459640 7.272842e-01 -0.1035949163
2183 O75947 ATP5PD 0.4118021525 1.353475e-01 -0.1058417568
2184 Q96GC9 VMP1 -0.2233382697 4.236564e-01 0.1094297534
2185 Q3SXM5 HSDL1 -0.1854799199 1.637189e-01 0.1196860011
2186 Q9BUL8 PDCD10 0.1918238493 4.235083e-01 -0.1721965292
2187 Q9UNS2 COPS3 -0.3244069419 4.765550e-03 0.2358430178
2188 P09417 QDPR 1.3486861831 8.097095e-09 -0.3650271906
2189 Q8TBQ9 TMEM167A -0.2189356800 7.927123e-02 0.0918088877
2190 Q01081 U2AF1 -0.0676163742 6.882073e-01 -0.0812919777
2191 Q9BRJ2 MRPL45 -0.0074385286 9.564850e-01 0.0907640999
2192 Q587I9 SFT2D3 -0.1349562351 5.906045e-01 -0.2000855117
2193 Q06787 FMR1 -0.6787913571 3.034775e-06 -0.2336430828
2194 P14866 HNRNPL -0.3486817978 6.150589e-03 -0.0752068166
2195 Q16537 PPP2R5E -0.2411305096 4.593771e-02 0.1207502672
2196 Q86W92 PPFIBP1 -0.2695018573 3.849201e-01 0.2147703958
2197 Q08170 SRSF4 0.1046135096 5.170669e-01 -0.2833920949
2198 P61011 SRP54 0.0336708567 8.227996e-01 0.0980445736
2199 Q6PD62 CTR9 -0.4087626385 1.213051e-03 -0.1536421186
2200 Q9H2M9 RAB3GAP2 -0.2033143942 1.300085e-01 -0.4297291464
2201 P04843 RPN1 0.0096436904 9.739276e-01 0.0737346295
2202 P35609 ACTN2 1.2117782012 2.205256e-03 0.1734007188
2203 O14639 ABLIM1 0.0752236362 7.385530e-01 0.1117955619
2204 P78357 CNTNAP1 0.8555630102 1.917259e-03 0.1205849581
2205 P51159 RAB27A 0.3175894687 3.343181e-01 -0.3207193545
2206 Q96SL4 GPX7 0.4885060433 4.088528e-01 -0.1548600142
2207 P35573 AGL 1.9252456142 3.197106e-05 0.1639074520
2208 O00116 AGPS 0.1102369880 3.853408e-01 0.1203514909
2209 Q8TAT6 NPLOC4 -0.5649133255 5.242117e-04 -0.1280768636
2210 Q9H0R6 QRSL1 0.5923842305 5.290926e-04 -0.1416605055
2211 Q12893 TMEM115 -0.3399088918 3.191682e-02 -0.1113613082
2212 Q9NP80 PNPLA8 -0.3398051775 1.331941e-01 -0.1098357922
2213 Q8NE62 CHDH 0.5216138962 2.483114e-01 -0.3189583107
2214 Q14151 SAFB2 -0.3802483246 2.512862e-02 0.1608753759
2215 A0FGR8 ESYT2 -1.3269197946 1.313129e-09 0.1680761578
2216 Q16836 HADH 0.5652787068 7.400782e-02 0.0870007334
2217 O43242 PSMD3 0.5980642266 6.966096e-07 0.0715412654
2218 Q86UL3 GPAT4 0.5470342177 5.963664e-03 -0.1374402276
2219 Q9BUJ2 HNRNPUL1 0.3559651845 1.639440e-02 -0.0845387504
2220 A5D6W6 FITM1 2.9683729634 1.358940e-02 -0.1310341467
2221 Q14764 MVP -0.2186500682 5.048069e-01 0.2875435215
2222 Q5BKX8 CAVIN4 0.4095006651 4.927518e-01 -0.3582403310
2223 Q02487 DSC2 1.0338189168 7.396651e-07 -0.2992525080
2224 Q9BQB6 VKORC1 0.3845824815 8.360751e-02 -0.1013794478
2225 P52179 MYOM1 1.9131442462 4.139588e-06 0.1245090072
2226 P62070 RRAS2 -0.1147385118 7.171943e-01 0.1169775237
2227 P49841 GSK3B -0.2447104250 9.266246e-02 0.1039484149
2228 Q8WXH0 SYNE2 0.4007482729 2.634036e-01 -0.3775847726
2229 O75845 SC5D 0.0618347845 9.166914e-01 -0.1260903235
2230 Q8IWX7 UNC45B 1.6474271890 2.027930e-06 -0.1210657317
2231 O14786 NRP1 1.0497861474 5.695981e-04 0.0870340184
2232 Q9H7Z7 PTGES2 0.9439969548 6.628375e-05 -0.0882905799
2233 P26006 ITGA3 -1.0814857623 2.601634e-02 -0.0830500422
2234 Q07817 BCL2L1 -1.2532111388 6.403973e-06 0.2486727601
2235 Q9UBR2 CTSZ -0.2193216438 4.541611e-01 0.1624464050
2236 Q86UE4 MTDH 0.1942338189 1.364889e-01 0.0729566441
2237 Q9UEW8 STK39 1.4645881202 3.238939e-08 0.1523180829
2238 P04004 VTN 0.3077547388 5.288148e-01 -0.2017070163
2239 O00214 LGALS8 -0.2246548423 4.490987e-01 0.1134130640
2240 Q12959 DLG1 0.5909028405 7.386090e-05 0.1109538226
2241 O60568 PLOD3 -0.2874368588 3.387479e-01 0.1068054840
2242 Q09161 NCBP1 0.2782718810 6.818212e-03 -0.0960413079
2243 P21283 ATP6V1C1 -0.1823192948 2.872729e-01 0.0873761706
2244 Q13636 RAB31 -1.1282784068 2.697689e-06 -0.5314522470
2245 P51790 CLCN3 0.8674120740 1.262030e-06 -0.1006003504
2246 O43772 SLC25A20 -0.2696840049 4.471466e-02 0.0940390925
2247 Q8N0U8 VKORC1L1 0.0850412058 7.524273e-01 0.1086948704
2248 P25786 PSMA1 0.6970245582 4.427227e-05 -0.0847909552
2249 Q13561 DCTN2 0.0309189326 8.268671e-01 -0.1095230216
2250 P46459 NSF -0.6141520033 2.017168e-03 0.0804018831
2251 Q8WWI1 LMO7 0.2695588353 2.100990e-01 -0.0892285079
2252 P05455 SSB 0.2220353768 9.929410e-02 0.0858122234
2253 Q7Z406 MYH14 0.7144758894 7.784809e-01 0.1126757023
2254 P21741 MDK -0.6601513678 7.623460e-02 0.2790916802
2255 Q99816 TSG101 -0.5358082905 5.565489e-08 -0.1254203323
2256 Q12802 AKAP13 0.2634402096 3.787848e-01 -0.2257237044
2257 P15151 PVR -0.2249349449 6.252877e-01 0.1422126943
2258 Q6IAA8 LAMTOR1 -0.0818105779 6.018847e-01 -0.1009985723
2259 Q96FV9 THOC1 0.8930647640 8.605784e-05 -0.1370294243
2260 Q9NP92 MRPS30 0.0935161655 6.658838e-01 -0.0847089711
2261 Q9ULD5 ZNF777 -0.1619445131 4.949122e-01 -0.1562769431
2262 Q7L8L6 FASTKD5 -0.4734031845 3.057090e-03 -0.1159447822
2263 O43676 NDUFB3 0.0348197043 9.200086e-01 0.0766864847
2264 O43920 NDUFS5 0.2235269835 5.393581e-01 -0.0739795048
2265 O15126 SCAMP1 0.2246440150 2.588138e-01 -0.0859143980
2266 P50613 CDK7 -0.0264044520 9.191317e-01 -0.1254557060
2267 Q9H490 PIGU 1.4090850298 5.930049e-07 0.0972435828
2268 Q15154 PCM1 -0.4528419457 9.935505e-03 0.1487439410
2269 Q8NFJ5 GPRC5A -1.6984613127 1.080710e-01 -0.2717517921
2270 Q02880 TOP2B 0.7928685525 2.583391e-11 0.0926080440
2271 Q7Z4H8 POGLUT3 1.5871024102 9.307457e-06 -0.1261352630
2272 P07900 HSP90AA1 0.2268566605 2.598713e-01 0.0905068804
2273 Q92890 UFD1 -0.3420062623 2.671656e-02 0.0887659687
2274 P82663 MRPS25 0.2122163225 2.916822e-01 0.0737885897
2275 Q16611 BAK1 -1.0772691463 9.510081e-04 -0.1149831719
2276 Q8N6H7 ARFGAP2 -0.1746849878 2.593567e-01 -0.3374250700
2277 Q9NVE7 PANK4 0.4321126233 1.797828e-02 0.1101018370
2278 Q15772 SPEG 1.4638370318 1.034254e-05 -0.1303646584
2279 P36507 MAP2K2 -0.1340735619 2.711267e-01 -0.2287493177
2280 O75821 EIF3G 0.0733741808 5.892635e-01 -0.1123255760
2281 Q9UPT8 ZC3H4 0.1977910173 2.150821e-01 -0.2464342913
2282 Q9NWH9 SLTM -0.0757628687 6.765655e-01 0.0908403974
2283 P01111 NRAS 0.3781786546 1.650738e-01 0.0738348777
2284 Q9P212 PLCE1 1.4128238530 1.758350e-05 0.1415246291
2285 P61077 UBE2D3 -0.2002922092 5.102552e-02 0.1467192230
2286 P14625 HSP90B1 0.4111294033 2.839828e-01 0.1024254477
2287 Q9BUT1 BDH2 0.6852905713 2.828355e-03 -0.1776385918
2288 Q9Y266 NUDC 0.3984925061 1.546301e-03 0.1157182200
2289 Q7Z4L5 TTC21B 0.7398097408 4.465813e-04 0.1374880575
2290 Q04446 GBE1 0.6553690204 5.264471e-03 0.1531357716
2291 O95232 LUC7L3 0.4983608791 9.545049e-03 -0.2887169637
2292 P62308 SNRPG 0.0172793718 9.547250e-01 -0.1457515613
2293 Q8IWW8 ADHFE1 0.1476809359 7.646353e-01 0.0985074284
2294 P15822 HIVEP1 -0.4079514547 1.613442e-01 -0.2172658475
2295 O94766 B3GAT3 -0.3922927046 1.426625e-01 -0.1352594561
2296 P34059 GALNS 0.3643727308 2.489842e-01 0.0921715696
2297 P30626 SRI 1.0432623040 3.476572e-06 -0.1421325502
2298 P34897 SHMT2 0.6745794025 8.732723e-05 -0.1104163534
2299 P09001 MRPL3 0.9374300831 1.496252e-07 -0.1001257790
2300 Q8WUK0 PTPMT1 0.7486204849 4.880568e-04 -0.1163135089
2301 Q8IZP0 ABI1 -0.0162363756 9.215519e-01 -0.1736190624
2302 Q9Y6M4 CSNK1G3 -0.0350858181 8.529185e-01 -0.2649024029
2303 P52758 RIDA 0.3317649635 2.271529e-01 0.1021859031
2304 P53801 PTTG1IP 0.1249992232 5.294926e-01 0.0838829868
2305 O75533 SF3B1 -0.0336202692 8.344448e-01 0.0894425931
2306 P82912 MRPS11 0.0559313376 7.857749e-01 0.0851335858
2307 Q9NZJ0 DTL 2.3985535906 7.819813e-07 -0.0843045692
2308 P29972 AQP1 2.2547102483 6.643097e-09 0.1341601670
2309 Q9NZI8 IGF2BP1 0.7446256123 2.260722e-05 -0.0839610247
2310 P14406 COX7A2 0.0777922045 8.548331e-01 -0.1699268375
2311 O14556 GAPDHS 0.7770135718 4.500282e-02 0.2212492989
2312 O14497 ARID1A -0.0030497592 9.901463e-01 -0.1342770987
2313 Q9H0E2 TOLLIP -0.5405509152 6.234638e-05 0.0897206701
2314 O95870 ABHD16A 0.5159231881 3.662427e-03 0.0747185461
2315 P39656 DDOST -0.4314026965 8.033659e-02 0.0828491160
2316 Q9UHA4 LAMTOR3 -0.3719507199 7.607481e-03 -0.0896908867
2317 Q9BT17 MTG1 -0.0142030324 9.478949e-01 0.0815812425
2318 Q15029 EFTUD2 -0.2037573353 1.365262e-01 -0.0618426621
2319 Q9C0J8 WDR33 0.2433898445 7.727531e-02 -0.3324290100
2320 P61221 ABCE1 0.5948428427 5.176238e-06 0.1800819437
2321 P21980 TGM2 0.6571123409 5.760362e-02 0.1409626170
2322 O14672 ADAM10 -0.3686718880 2.818300e-01 -0.1065539456
2323 P49023 PXN -0.2555707420 1.725348e-01 -0.1027252454
2324 Q9Y6N7 ROBO1 0.6055548432 6.889263e-02 0.1904771436
2325 P60953 CDC42 -0.2062601515 1.404962e-01 -0.0619750593
2326 P20700 LMNB1 -0.0401274632 8.797037e-01 0.0736560770
2327 P09525 ANXA4 -2.0762293471 1.775044e-10 0.1921985332
2328 Q5VST9 OBSCN 1.9657388755 9.141551e-06 0.1144003231
2329 P36776 LONP1 0.1993639520 1.989495e-01 0.0730809005
2330 Q8IZ81 ELMOD2 0.5734409147 1.816252e-02 0.0831898312
2331 Q8TCJ2 STT3B 0.2127207135 2.548533e-01 0.0889680834
2332 O96005 CLPTM1 -0.1382258477 5.283851e-01 0.1025729723
2333 Q9UNH7 SNX6 0.6293863778 3.499151e-05 0.1144396456
2334 O60884 DNAJA2 0.0634284390 6.324113e-01 0.0786412110
2335 Q9BTY2 FUCA2 0.4167218015 2.410173e-01 0.0884052326
2336 P51148 RAB5C -0.4251364040 1.835069e-01 -0.1127880732
2337 Q9Y679 AUP1 -0.3700852374 1.829319e-02 0.1281353183
2338 Q9Y399 MRPS2 0.8713937049 6.025728e-08 -0.1081825184
2339 Q9NP58 ABCB6 -1.7819160928 1.071398e-08 -0.2081219846
2340 P25686 DNAJB2 -0.3764083310 5.021972e-02 -0.4409429218
2341 Q8NFD5 ARID1B 0.1649458813 3.779063e-01 0.1173360257
2342 Q9HC21 SLC25A19 -0.5451086200 2.190423e-02 0.1441435639
2343 Q9Y3A5 SBDS 0.4518700340 1.258558e-02 -0.2567924331
2344 Q7Z7H5 TMED4 -0.1400053220 2.312305e-01 0.0845505602
2345 Q9NX62 BPNT2 0.0824927707 6.090531e-01 -0.1586894490
2346 Q9NV96 TMEM30A -0.3802463385 8.611958e-02 -0.1079970578
2347 Q6JBY9 RCSD1 1.4050248084 2.002982e-03 -0.2245187743
2348 Q7Z3C6 ATG9A 0.4232071809 2.680046e-03 0.1369346901
2349 O15118 NPC1 -0.6786219897 2.564494e-02 0.1870225847
2350 O94875 SORBS2 0.8466433842 7.652204e-04 0.1058970244
2351 P43243 MATR3 0.1346123482 5.733979e-01 -0.0599042013
2352 O00410 IPO5 0.0388070439 8.220781e-01 0.0771344886
2353 Q5T3F8 TMEM63B -0.8899017684 2.523434e-05 0.4780829378
2354 P52789 HK2 0.1052990652 8.475792e-01 -0.1481672261
2355 P21266 GSTM3 0.1396641502 6.626186e-01 0.1084883898
2356 Q00610 CLTC 0.4570964549 8.554795e-04 -0.1013205733
2357 Q9NXG0 CNTLN 0.8301658116 2.358548e-03 -0.0710025079
2358 Q8WVM8 SCFD1 -0.0166513041 9.101552e-01 -0.0876495577
2359 P16152 CBR1 0.3369572776 3.665830e-01 0.1268421232
2360 Q9NVC3 SLC38A7 -0.0230360023 9.398638e-01 -0.1204226051
2361 P50148 GNAQ -0.5176245426 2.150925e-02 0.3021785170
2362 P18031 PTPN1 -1.0298878141 2.400114e-05 0.1311139807
2363 P30825 SLC7A1 0.9445964951 3.420367e-04 -0.1813939844
2364 Q9HCP6 HHATL 1.2634805253 2.191637e-01 0.2888851845
2365 O75381 PEX14 0.3491617120 2.690376e-02 -0.3211125770
2366 Q15427 SF3B4 0.1870032303 1.920420e-01 0.0870051810
2367 Q8NBJ7 SUMF2 0.5456688017 5.050998e-02 -0.2050417704
2368 Q96KM6 ZNF512B 1.2616455509 1.903062e-04 0.1082226486
2369 P13637 ATP1A3 2.8038238320 3.926380e-08 -0.0967763612
2370 Q9HD45 TM9SF3 0.1313191994 4.994314e-01 -0.0819738690
2371 Q96EY8 MMAB 0.6748654000 9.696859e-05 0.1012971614
2372 Q9H1I8 ASCC2 -0.0170807523 9.416420e-01 -0.1393803706
2373 Q9Y6K1 DNMT3A 0.0163411504 9.416420e-01 -0.0977244009
2374 Q9H300 PARL -0.1307387069 2.023490e-01 -0.1082308510
2375 Q7Z3K3 POGZ 0.4362730969 5.150607e-03 -0.1207296815
2376 Q99439 CNN2 0.8377840511 5.309659e-02 0.2513663604
2377 P51648 ALDH3A2 0.5719194395 1.389925e-02 0.0906536098
2378 Q12830 BPTF -0.1414491576 4.189015e-01 0.0872596919
2379 Q02750 MAP2K1 -0.1052212653 6.661304e-01 -0.1759906539
2380 Q9UHB9 SRP68 -0.9555278494 7.172050e-07 0.1405647965
2381 P11532 DMD 0.8686020943 6.162823e-03 0.0646041166
2382 Q9Y592 CEP83 1.2257758177 3.953353e-06 0.2047931412
2383 P09104 ENO2 0.5985469728 5.799643e-01 0.1608794301
2384 Q5JPH6 EARS2 0.4069693423 1.294753e-01 0.0948825802
2385 Q14699 RFTN1 -0.6521454800 6.470766e-03 0.0949489874
2386 O75694 NUP155 0.5991875782 3.478329e-04 -0.1245720630
2387 Q14008 CKAP5 -0.4389918745 2.524708e-03 0.0912575656
2388 Q7L014 DDX46 0.1218455874 5.104887e-01 -0.0790218635
2389 P52597 HNRNPF -0.3305074757 5.547817e-02 0.0617895394
2390 P08294 SOD3 0.0937949214 7.431747e-01 -0.1946003311
2391 O43264 ZW10 0.7310688837 9.812131e-04 -0.1261748207
2392 O60245 PCDH7 0.7495802771 6.083667e-04 0.1198399987
2393 P11171 EPB41 -0.0254643741 9.279437e-01 0.0931591291
2394 Q04721 NOTCH2 -0.0421000924 9.051863e-01 0.2346299767
2395 Q6UN15 FIP1L1 0.0493975885 7.777428e-01 -0.1282771596
2396 Q9UNF0 PACSIN2 -0.5023746472 5.340197e-04 0.1079347491
2397 Q9BVC4 MLST8 0.4733889899 1.062802e-02 0.3032040546
2398 Q6P1K8 GTF2H2C 0.3244639326 1.200738e-01 -0.1412766968
2399 P51659 HSD17B4 0.5574602088 2.560487e-04 0.0757533862
2400 Q92504 SLC39A7 0.7985954291 1.682925e-05 -0.2901717026
2401 Q5HYJ1 TECRL 1.1552446549 1.236416e-02 -0.0813971200
2402 Q96D71 REPS1 0.3125509237 1.910829e-02 -0.1036203253
2403 Q5CZC0 FSIP2 2.1208301759 8.097095e-09 -0.2871359169
2404 Q709F0 ACAD11 0.0557420518 8.641535e-01 0.0927170442
2405 O43402 EMC8 -0.1140199597 4.358335e-01 -0.1210832613
2406 P30419 NMT1 0.3165557419 2.024316e-03 -0.2153199384
2407 Q9NUI1 DECR2 0.5272927256 4.096170e-02 -0.0881000495
2408 Q9NTZ6 RBM12 -0.5190400624 2.735487e-03 -0.1060989067
2409 Q6Y1H2 HACD2 0.8619514419 3.567381e-02 0.1465031580
2410 Q86YH6 PDSS2 0.6033452360 1.028914e-02 0.1028414606
2411 P08727 KRT19 -1.9500320846 3.126264e-04 -0.1061158880
2412 Q7Z5G4 GOLGA7 0.2375474817 6.133869e-02 -0.1369039624
2413 Q5T9A4 ATAD3B 0.9145547943 9.359890e-06 0.1442396124
2414 Q9BZJ0 CRNKL1 -0.1316039742 3.611632e-01 0.0877489549
2415 Q9BQS7 HEPH 0.2046066661 6.067403e-01 -0.1148999158
2416 Q12874 SF3A3 0.0819311102 6.100667e-01 -0.0595385098
2417 Q9HBM0 VEZT 0.3522668572 3.037280e-02 -0.1374230842
2418 Q9HC38 GLOD4 0.4430369369 1.699268e-04 0.1953545833
2419 P51991 HNRNPA3 -0.1801884270 4.129760e-01 -0.0620973090
2420 P67812 SEC11A 0.0774137063 7.470536e-01 0.0748921936
2421 P61604 HSPE1 0.0924421731 6.975348e-01 -0.0620710869
2422 Q5VWN6 TASOR2 -0.2041902220 1.625263e-01 -0.4288009796
2423 P51911 CNN1 1.2440751036 2.226766e-02 0.1384804369
2424 P78324 SIRPA -0.0376881173 8.597583e-01 -0.0847598614
2425 Q5TB80 CEP162 0.9806911168 2.122293e-05 0.1805441998
2426 Q9NUQ9 CYRIB -0.2160941947 2.692079e-01 0.1091918315
2427 Q8N1F7 NUP93 0.4738018173 2.638992e-04 0.0711521136
2428 Q86Y82 STX12 -1.6124420699 1.844188e-12 -0.0856437451
2429 P23142 FBLN1 0.5082271882 8.116395e-02 0.1297259522
2430 Q9BTZ2 DHRS4 -0.5070912785 1.451382e-02 0.0793866019
2431 Q96JN8 NEURL4 0.7213982353 1.756922e-04 -0.1397817948
2432 Q8NHY6 ZFP28 0.8708184850 1.527098e-03 -0.1475344644
2433 Q9Y282 ERGIC3 0.0160967765 9.399329e-01 -0.0739991423
2434 P08621 SNRNP70 0.0853912404 6.169122e-01 0.0534982205
2435 P06241 FYN -0.0991840519 7.135396e-01 -0.1558970226
2436 O75718 CRTAP 0.2891110521 3.582692e-01 -0.1819304406
2437 O95258 SLC25A14 0.2926980071 1.679156e-01 0.1631335603
2438 P51511 MMP15 1.2192276705 7.380313e-06 -0.1290989825
2439 P54098 POLG -0.5059588808 4.352882e-03 0.2152391720
2440 Q96I24 FUBP3 -0.2383924291 1.050097e-02 0.0602492565
2441 Q16629 SRSF7 1.2595757422 6.354545e-08 0.0612927978
2442 Q8WW59 SPRYD4 -0.1128651061 6.829595e-01 0.0841171863
2443 Q8WUP2 FBLIM1 0.5717179577 4.491768e-03 -0.3000307376
2444 Q9UFN0 NIPSNAP3A 0.1752720862 6.361333e-01 0.0829878556
2445 P18887 XRCC1 0.7302841694 3.552244e-05 0.2159481018
2446 Q15118 PDK1 0.8146132774 1.484807e-01 -0.1283095144
2447 Q9Y5X1 SNX9 0.2038400227 1.074654e-01 -0.2385094504
2448 Q92804 TAF15 0.0903404643 6.038390e-01 0.0767138242
2449 O94826 TOMM70 0.2108903696 1.558634e-01 0.0614062043
2450 Q9BT22 ALG1 0.4991754120 1.261137e-01 0.1188140781
2451 Q9BTU6 PI4K2A -0.7877622293 8.846913e-06 -0.1206832245
2452 O75489 NDUFS3 0.2345735640 4.628069e-01 0.0619173253
2453 P04899 GNAI2 0.8901251476 2.304169e-05 0.0562996012
2454 Q9UKL0 RCOR1 -0.4830987671 2.121440e-03 -0.1213965636
2455 O43237 DYNC1LI2 -0.4810024045 1.562862e-02 0.0930778627
2456 Q9NYU2 UGGT1 0.1535375276 5.078204e-01 0.0707409224
2457 P09471 GNAO1 1.4284544938 4.120712e-02 -0.3247831088
2458 Q9Y2G3 ATP11B -0.0687453930 7.528601e-01 0.1444940203
2459 P84243 H3-3B -1.5299856374 1.967564e-08 0.0855893319
2460 P84243 H3-3A -0.8451934983 9.458782e-06 0.0855893319
2461 Q01995 TAGLN 0.7038730596 2.736851e-01 0.0742650185
2462 O75600 GCAT 0.6727060803 4.996000e-04 0.1441389849
2463 Q9HCN8 SDF2L1 0.6745502609 6.661735e-02 -0.1299348778
2464 Q9Y2G5 POFUT2 0.0653514999 8.314755e-01 -0.1205426272
2465 Q96GW9 MARS2 0.5568052163 2.809161e-02 0.1340874103
2466 Q9H1U9 SLC25A51 -0.0798470763 7.289997e-01 0.2583978467
2467 Q9Y2C4 EXOG 1.1113055777 4.340975e-06 0.1445189602
2468 P08729 KRT7 -1.0801937457 4.287329e-01 -0.3305501575
2469 P48681 NES 0.9081946152 4.814416e-05 0.0796570446
2470 P19634 SLC9A1 -2.0830189739 4.574836e-10 -0.0886286246
2471 Q92769 HDAC2 -0.3786520640 1.554878e-02 -0.0541289871
2472 Q92536 SLC7A6 -0.0295804145 9.345997e-01 -0.1004231165
2473 P05783 KRT18 0.8829370736 2.728087e-02 0.1288285946
2474 Q9HBR0 SLC38A10 -0.2054667644 3.267505e-01 -0.1495131227
2475 P55010 EIF5 -0.7255456588 3.516704e-06 -0.1105096109
2476 Q96HV5 TMEM41A -1.3469975421 2.551398e-07 -0.2174351445
2477 Q9UNF1 MAGED2 -0.0957153952 5.526410e-01 0.1901594665
2478 Q9BYG3 NIFK 0.0537970296 7.947659e-01 -0.0978764034
2479 P67775 PPP2CA -0.0423444468 8.083169e-01 -0.0749985487
2480 P60709 ACTB 1.1911733904 1.401556e-01 0.1634659964
2481 Q13131 PRKAA1 0.1296500008 2.167016e-01 -0.1357777971
2482 Q8IYQ7 THNSL1 -0.7286837089 2.167999e-06 0.0875681758
2483 O60493 SNX3 0.3991619387 9.883046e-02 -0.1144799855
2484 P31040 SDHA -0.2526259768 1.385651e-01 0.0558060876
2485 Q9H5K3 POMK 0.1578527482 7.635140e-01 0.1805844137
2486 P50479 PDLIM4 -1.2100168591 3.035880e-03 -0.1577712949
2487 Q9H061 TMEM126A 0.7792589366 1.141553e-02 0.0779471456
2488 Q16527 CSRP2 0.1250032734 6.021855e-01 0.2286784808
2489 P21127 CDK11B -0.0235672707 9.112240e-01 0.1627577810
2490 Q96K37 SLC35E1 0.1096222361 5.222702e-01 -0.1089010353
2491 Q9NQ55 PPAN 0.5854203463 1.361376e-02 -0.0892782974
2492 P62834 RAP1A -0.2678312595 1.136761e-01 0.0578455041
2493 Q9C0E8 LNPK 0.8951907119 8.678073e-05 0.0550928263
2494 Q9Y375 NDUFAF1 0.0915894425 5.412275e-01 0.0734868250
2495 Q8N138 ORMDL3 0.0062261328 9.855048e-01 0.0789106195
2496 Q5VIR6 VPS53 -0.3552433128 1.079929e-02 -0.2099405738
2497 P98194 ATP2C1 0.5343361766 1.338103e-01 -0.1257401496
2498 P43897 TSFM 0.3252331428 1.126874e-01 -0.0751401884
2499 Q9H8H3 METTL7A -0.7904047700 4.045716e-02 0.2242387378
2500 Q9Y5F9 PCDHGB6 0.6461228342 4.735124e-02 0.1129622774
2501 O14734 ACOT8 -0.2436383717 1.284014e-01 0.1129221016
2502 Q16891 IMMT 0.5224613214 1.933882e-03 0.0560931318
2503 Q8NCC3 PLA2G15 -0.8859299390 6.473601e-03 0.0497102537
2504 P05106 ITGB3 0.7443954844 1.543798e-01 0.0778740923
2505 P53370 NUDT6 0.4598502798 3.157219e-01 -0.1040273457
2506 Q9NSE4 IARS2 0.0250475764 8.634162e-01 0.0493371209
2507 P35611 ADD1 0.1515286412 4.311913e-01 0.0631656805
2508 Q9H479 FN3K 1.4720558600 4.565326e-05 -0.0787604221
2509 Q9Y584 TIMM22 -0.0199925200 9.023055e-01 -0.0652351852
2510 Q8WUM0 NUP133 0.5263330289 3.070939e-08 0.0557621505
2511 Q08211 DHX9 0.1048349930 4.404153e-01 0.0499441591
2512 O75608 LYPLA1 0.5139354865 6.682146e-03 -0.0745766017
2513 Q969S9 GFM2 -0.1654798434 4.223064e-01 0.0627647987
2514 Q7Z2K6 ERMP1 0.3622874046 9.257619e-02 -0.0548550915
2515 Q9UBV2 SEL1L 0.3718793581 6.370818e-02 -0.1622552518
2516 Q13797 ITGA9 0.1553046783 8.118748e-01 -0.2519755185
2517 Q8WZ42 TTN 1.5503118991 1.548083e-03 0.0794226318
2518 O14964 HGS -0.3479797435 3.814316e-03 0.0820228802
2519 Q9NRZ7 AGPAT3 1.3129524979 6.851935e-09 0.1647658519
2520 Q5VWZ2 LYPLAL1 -0.0273748120 9.436764e-01 0.0735450958
2521 P54296 MYOM2 1.5783967642 2.917550e-01 0.2667490413
2522 P22033 MMUT 0.6045395885 2.020883e-04 -0.0479088336
2523 O75340 PDCD6 -0.7721646252 3.484750e-08 0.0963472520
2524 O15347 HMGB3 0.0292633899 8.987883e-01 -0.1528647031
2525 O60437 PPL -0.5370936912 9.853099e-02 -0.0992150100
2526 Q86VF7 NRAP 2.0533013326 8.793317e-02 -0.1724454292
2527 Q9UJ14 GGT7 0.5518019154 1.800319e-01 -0.1841651940
2528 Q14126 DSG2 -0.2950398271 2.745787e-01 0.0906490385
2529 Q9Y305 ACOT9 0.4473976546 9.166317e-02 0.0817539898
2530 O14681 EI24 -2.0223453547 1.700569e-15 0.0504328211
2531 Q96L92 SNX27 -0.2770092005 3.454181e-02 -0.0705107713
2532 Q16643 DBN1 1.1371670784 4.013151e-05 0.1143371074
2533 P08648 ITGA5 0.4052198196 2.276024e-01 0.0524227625
2534 Q16740 CLPP 0.5735338690 2.478798e-04 -0.1587609777
2535 Q9UKV8 AGO2 0.2153615252 2.492656e-01 -0.1227335619
2536 O60443 GSDME -1.1530519198 3.116827e-02 0.0673076311
2537 Q8IZL8 PELP1 -0.0692630422 6.170311e-01 -0.0510384229
2538 Q15262 PTPRK 0.5173309033 3.138572e-03 -0.0921836037
2539 P17405 SMPD1 -0.0446406350 8.815904e-01 -0.0985026308
2540 P06280 GLA -1.0809752169 7.218259e-04 -0.6437860755
2541 Q96AG3 SLC25A46 0.2054926854 2.743544e-01 0.0708928605
2542 P40616 ARL1 0.1872647105 2.107712e-01 -0.0838050306
2543 Q9Y5M8 SRPRB 1.4256986965 3.557126e-05 0.0726368661
2544 O95202 LETM1 0.8533270403 3.412074e-05 0.0636825497
2545 Q8N4Q0 PTGR3 0.0837654112 7.135981e-01 0.0761522567
2546 Q6NVY1 HIBCH -1.0351287184 1.887305e-04 0.0922761288
2547 Q96QR8 PURB 0.0801388864 6.079252e-01 -0.0655748310
2548 O14818 PSMA7 0.7813855124 2.740252e-04 0.0581191834
2549 Q86TX2 ACOT1 -0.2123781167 6.692364e-01 0.1315817143
2550 Q9BRR6 ADPGK 0.2268054422 3.644632e-01 0.1056158330
2551 O14967 CLGN 0.4097482788 2.562461e-01 0.0707776703
2552 Q8IYB3 SRRM1 0.3680207351 4.183113e-02 -0.0414084075
2553 Q96BR5 COA7 0.2017047247 1.890797e-01 -0.0518231100
2554 Q13574 DGKZ -0.5074002197 1.607816e-03 -0.3396388305
2555 P10515 DLAT 1.6015165667 1.176204e-09 0.0508710536
2556 Q96HY7 DHTKD1 0.5985503520 6.565498e-04 -0.0529012086
2557 O14548 COX7A2L -0.3528133514 6.966400e-02 -0.0806063366
2558 Q9H5Q4 TFB2M 0.4670297498 2.600783e-02 0.1169364628
2559 Q92922 SMARCC1 0.0934443982 7.049648e-01 -0.0854619480
2560 Q9UBH6 XPR1 -1.4167253053 7.564749e-06 -0.1026575628
2561 Q9NZL9 MAT2B -0.3424379218 4.381741e-03 0.0814487887
2562 Q9NVJ2 ARL8B -0.8362189775 6.131492e-08 0.0652141143
2563 Q9GZM5 YIPF3 -0.1492491534 3.275521e-01 -0.0734036437
2564 Q5SNT2 TMEM201 0.3870492789 2.320300e-02 0.0535184450
2565 O95487 SEC24B -0.1592382477 1.990496e-01 -0.1845001171
2566 Q9H330 TMEM245 -0.0988973725 6.661304e-01 0.0432196652
2567 Q96RP9 GFM1 0.2436572748 1.876704e-01 0.0594675096
2568 P05067 APP 0.0152687436 9.489411e-01 0.1316403122
2569 Q9BWH2 FUNDC2 0.0606475663 8.170769e-01 0.0656759520
2570 Q9NX20 MRPL16 0.9064266818 2.849637e-05 0.0633923043
2571 P14324 FDPS 0.1416346638 6.142191e-01 -0.1189814702
2572 Q8N183 NDUFAF2 0.1511105735 5.099439e-01 -0.3719138913
2573 Q5BJH7 YIF1B 1.4253199703 3.019843e-06 -0.0547789758
2574 O15439 ABCC4 0.0407828947 9.190308e-01 0.0771259883
2575 Q00577 PURA 0.0127208563 9.609405e-01 0.0583589862
2576 Q9Y6W5 WASF2 -0.2199023452 2.402674e-01 0.1141249087
2577 P50443 SLC26A2 -1.3479890063 3.766949e-03 0.1592965558
2578 Q8TED1 GPX8 3.0484685694 1.554146e-13 -0.0735621163
2579 O95292 VAPB -0.1094827710 4.378143e-01 0.0529490794
2580 Q13155 AIMP2 0.5819064719 1.422933e-03 -0.0727988731
2581 Q9NSC5 HOMER3 -0.3354888628 1.148090e-01 0.1150353643
2582 O75964 ATP5MG -0.0493905276 8.902135e-01 0.0555807615
2583 Q9H0U3 MAGT1 0.3562946865 2.173729e-01 0.0633195394
2584 P00338 LDHA 1.0587934995 2.409196e-01 0.1281426199
2585 Q9H583 HEATR1 0.3391123324 1.867005e-01 0.1074838635
2586 P16435 POR -1.2655279567 1.190999e-06 0.0649701875
2587 Q9Y289 SLC5A6 0.1885906139 4.560770e-01 0.1127788448
2588 Q14156 EFR3A 0.2685704152 2.857056e-01 0.0698061455
2589 O00203 AP3B1 0.0914340384 4.652111e-01 0.0609040878
2590 P78406 RAE1 -0.3100844999 9.315030e-03 0.0640348902
2591 Q9UMR2 DDX19B 0.0014752820 9.908899e-01 -0.0840773046
2592 P61812 TGFB2 -0.5931954178 9.720795e-02 -0.2186484648
2593 Q86SF2 GALNT7 -0.1966649504 7.484510e-01 -0.1319875469
2594 P55072 VCP -0.0419526871 7.709822e-01 -0.0484511095
2595 P14735 IDE 0.6256251410 1.614125e-06 -0.1009494947
2596 O75494 SRSF10 0.5445494331 1.857462e-04 -0.0958188961
2597 Q9UQ90 SPG7 0.3105730123 5.316283e-02 -0.0628197679
2598 O14617 AP3D1 -0.4318239693 3.673295e-03 0.0785024751
2599 P78527 PRKDC 0.2782599456 1.202798e-01 0.0423821780
2600 Q08378 GOLGA3 -0.4409489163 1.087242e-02 0.0851271048
2601 Q8WXI4 ACOT11 1.4115676530 6.509022e-07 0.0780277235
2602 P41091 EIF2S3 0.1812784296 2.685841e-01 -0.0506670771
2603 Q13526 PIN1 -0.3255357436 4.916231e-02 0.0955737571
2604 Q9UI10 EIF2B4 0.3601553688 9.562356e-04 0.2355937702
2605 P05026 ATP1B1 0.2768670516 3.258210e-01 -0.0436296616
2606 O60518 RANBP6 0.0480501091 8.732040e-01 -0.1015523148
2607 Q9H845 ACAD9 0.1266353329 1.610315e-01 0.0554651052
2608 A6NK58 LIPT2 0.1309436026 7.460294e-01 0.0661541060
2609 Q3ZCQ8 TIMM50 0.5117820878 2.736684e-04 0.0582774510
2610 Q9HCH3 CPNE5 -0.2321974841 4.828487e-01 -0.1007581731
2611 O75880 SCO1 0.0842102825 6.119409e-01 0.0590593941
2612 Q10469 MGAT2 0.1004830131 5.478646e-01 0.0690940739
2613 P82650 MRPS22 0.2482159660 2.379069e-01 0.0534350875
2614 Q9H078 CLPB 1.0532811603 6.131492e-08 -0.0899252875
2615 Q9UJY1 HSPB8 -1.0598526509 3.307007e-06 -0.0805324053
2616 Q9UH62 ARMCX3 -0.4069138156 1.286143e-02 -0.0958888585
2617 Q8WU76 SCFD2 1.5317503551 2.385808e-05 -0.0840733440
2618 Q2TAA2 IAH1 0.6672248678 7.584923e-02 -0.1699194872
2619 P98175 RBM10 0.3394993051 8.940688e-03 -0.0732169941
2620 Q9NPA0 EMC7 -0.3903013917 3.918018e-02 0.0652774520
2621 Q12931 TRAP1 0.7068623097 2.162977e-06 0.0574071475
2622 P10599 TXN -0.4839048918 1.833892e-01 -0.0676638518
2623 Q13200 PSMD2 -0.2148143779 1.783229e-01 0.0475088875
2624 P83111 LACTB -0.2707482119 3.348552e-02 0.0705257544
2625 P05023 ATP1A1 -0.0995814694 6.895934e-01 0.0403098199
2626 Q6PI48 DARS2 0.6837442563 3.079227e-06 0.0626504584
2627 O43809 NUDT21 0.4052185510 2.138124e-03 -0.1246001420
2628 Q99986 VRK1 0.7325617825 3.881177e-02 0.3203400277
2629 Q9Y6X4 FAM169A 0.6938112613 3.995721e-03 0.0592569582
2630 O43324 EEF1E1 0.9867779144 5.131606e-04 -0.1899648976
2631 P48509 CD151 0.1635675502 4.784343e-01 0.0842260211
2632 P35052 GPC1 -0.0879123208 6.383740e-01 -0.1470547036
2633 Q9NZ45 CISD1 0.4159239357 2.132812e-01 -0.0567521175
2634 Q16563 SYPL1 0.3795805055 8.407325e-03 0.1345546282
2635 Q9Y3D6 FIS1 0.3357572162 1.861721e-01 -0.1104808456
2636 D6RIA3 C4orf54 -1.7968489000 2.496839e-04 -0.1081073911
2637 Q05639 EEF1A2 1.6832224831 1.848845e-07 0.0832158192
2638 Q15056 EIF4H -0.6116727151 1.151303e-06 0.0854103602
2639 O75648 TRMU 0.8604649782 1.067794e-04 0.0607986277
2640 Q6PIF6 MYO7B 0.8429421466 1.387979e-01 -0.0828737441
2641 P62879 GNB2 -0.1653011337 2.851546e-01 -0.0485644451
2642 Q9NRG7 SDR39U1 0.2985167008 1.985132e-01 -0.1430473443
2643 Q99735 MGST2 -0.1700401697 5.268783e-01 -0.0558466744
2644 Q07954 LRP1 -0.3349441725 3.537431e-01 -0.0723738317
2645 P54578 USP14 0.2514016694 7.706288e-02 -0.0916852238
2646 Q01974 ROR2 1.2672147544 9.680216e-03 -0.0722757987
2647 Q9NQH7 XPNPEP3 0.0530862921 7.377871e-01 -0.0657496183
2648 Q14160 SCRIB -0.6435861716 5.474390e-04 0.0615592583
2649 Q9UI43 MRM2 -0.4076633948 1.818576e-03 -0.0707575688
2650 P17540 CKMT2 0.3580122056 5.176419e-01 0.0504446365
2651 Q99538 LGMN -0.4976071817 2.054690e-01 0.1282354493
2652 O15049 N4BP3 0.4215966539 1.420118e-01 0.0837154845
2653 Q9H920 RNF121 0.1502067048 3.629881e-01 -0.0500147316
2654 Q9Y5S9 RBM8A -0.2469778184 1.716700e-02 -0.0998954406
2655 Q96KP4 CNDP2 0.6598520480 4.018998e-04 0.0930430190
2656 Q5HYI7 MTX3 -0.5461515008 9.301754e-05 -0.1275601756
2657 P98196 ATP11A 0.6328987985 7.387914e-04 0.1411533919
2658 Q96AB3 ISOC2 1.0831514061 3.552244e-05 -0.0773212472
2659 Q8N128 FAM177A1 -0.2268155265 2.248883e-01 0.0706439264
2660 Q9BYD2 MRPL9 0.1396258467 5.212238e-01 -0.0492047624
2661 Q6WCQ1 MPRIP -0.7807004684 1.126835e-06 -0.1613623152
2662 O95782 AP2A1 -0.0097067352 9.391114e-01 0.0457570291
2663 Q96JB5 CDK5RAP3 -0.5245609230 5.048248e-04 -0.0546585614
2664 Q9NRC6 SPTBN5 0.5077932744 3.365473e-01 -0.1027994903
2665 Q92974 ARHGEF2 0.7632771201 3.678876e-06 -0.1406441587
2666 Q96N67 DOCK7 0.0611686180 6.506806e-01 0.0721885534
2667 Q9UQM7 CAMK2A -0.5609558277 2.435398e-01 -0.0582152129
2668 P16949 STMN1 0.3835150936 8.016840e-02 -0.1363541714
2669 P10620 MGST1 0.7336422732 6.965271e-02 -0.0648036547
2670 Q9Y383 LUC7L2 -0.0364676557 8.966021e-01 -0.0508557701
2671 P46940 IQGAP1 -1.0625544249 1.057504e-01 -0.1615421363
2672 P07686 HEXB -0.3352275762 3.900074e-01 0.0476819765
2673 Q5T653 MRPL2 0.4129304291 1.076757e-01 0.0659755779
2674 Q70CQ2 USP34 0.4087772356 4.361926e-04 0.0599315830
2675 P32322 PYCR1 1.5524154653 1.103013e-08 0.0586004526
2676 Q9P016 THYN1 0.6238648553 9.355885e-04 -0.0942341510
2677 O95772 STARD3NL 0.6361316416 1.547445e-03 -0.1393674627
2678 Q9NVI7 ATAD3A 1.3949761759 8.073924e-13 0.0492057469
2679 Q9UIG8 SLCO3A1 1.2094959376 2.321652e-08 -0.1126949802
2680 Q6UVY6 MOXD1 -0.0134253435 9.902724e-01 0.2286318734
2681 O95807 TMEM50A -0.0549467221 7.754355e-01 0.0619011946
2682 Q9NQX4 MYO5C 0.8751175315 7.295568e-02 0.1939865053
2683 Q96HE7 ERO1A 0.5832648632 1.311261e-01 -0.0658820362
2684 Q9Y2D5 PALM2AKAP2 1.5083646100 2.554631e-04 -0.0560915416
2685 P36957 DLST -0.0777303111 5.022038e-01 0.0488353820
2686 Q9NWU5 MRPL22 0.4324154719 1.720433e-02 0.0763464017
2687 Q9NWU1 OXSM -0.0799563404 8.151385e-01 0.2012832619
2688 Q01650 SLC7A5 -0.7509730942 2.103451e-01 0.1411293422
2689 Q9Y2Z9 COQ6 -0.3303364544 2.087049e-02 -0.0833031421
2690 P27816 MAP4 -0.0111065627 9.705725e-01 0.0922741439
2691 P07225 PROS1 -0.0971194305 6.101213e-01 -0.0965151172
2692 Q9NUJ1 ABHD10 0.9066565276 2.461916e-04 -0.0587708345
2693 P32418 SLC8A1 3.1835431479 4.769101e-09 0.0452835669
2694 Q9NP72 RAB18 -0.3874919938 2.647971e-03 -0.0887283708
2695 Q9NVV4 MTPAP 0.4799515097 2.349367e-03 0.1146156235
2696 P08754 GNAI3 -0.3409940351 2.232265e-01 -0.0781616066
2697 O43760 SYNGR2 -0.0342205186 8.815993e-01 0.0756914626
2698 P17812 CTPS1 -1.1167805358 7.091370e-03 0.0835420863
2699 O75152 ZC3H11A 0.0624688295 6.256821e-01 0.1437682787
2700 P20810 CAST -0.0714795511 6.765701e-01 -0.0818775766
2701 Q7L3T8 PARS2 -0.1565213656 4.748472e-01 0.0663663904
2702 Q86WU2 LDHD 0.7281306332 3.067223e-02 -0.1427661689
2703 Q14738 PPP2R5D -0.1121890011 4.876574e-01 -0.1247885566
2704 P57088 TMEM33 0.1295374324 4.195866e-01 -0.0383958437
2705 O95249 GOSR1 -0.0449952471 7.442568e-01 -0.2318964369
2706 Q2PZI1 DPY19L1 -0.3295427484 1.864519e-01 0.0545807289
2707 Q13454 TUSC3 -0.2052341348 2.053194e-01 0.0811115859
2708 P63261 ACTG1 0.9124379264 2.017725e-01 0.1514098541
2709 Q9UBS9 SUCO -1.1114626973 7.774826e-08 -0.0588708025
2710 P08195 SLC3A2 -0.8988803890 3.124818e-02 0.0999257085
2711 O00299 CLIC1 0.8938427485 5.660302e-03 -0.0478113576
2712 O75298 RTN2 1.1554884367 2.486770e-04 0.0659977777
2713 Q04837 SSBP1 0.1737329458 2.162510e-01 0.0373694231
2714 Q13618 CUL3 -0.2401622985 6.957132e-02 -0.1004011916
2715 Q9BXK5 BCL2L13 -0.1482820028 1.521714e-01 0.0521963085
2716 P21333 FLNA -1.0136720766 1.202798e-01 0.1265936731
2717 P14415 ATP1B2 1.0374333676 7.894786e-03 0.1662601308
2718 Q8IYS2 KIAA2013 -0.4848078958 1.193138e-04 0.0395207619
2719 Q8N6T3 ARFGAP1 -0.9167574926 2.259300e-06 0.1125089163
2720 P53618 COPB1 0.3977257043 4.226960e-02 -0.0497748823
2721 Q96BM9 ARL8A -0.9854771003 4.190086e-10 0.0767938406
2722 Q9P0K7 RAI14 0.8155768340 1.994095e-03 0.0693240416
2723 Q9HAV0 GNB4 0.9868231804 7.083006e-05 0.1343798366
2724 Q96TA2 YME1L1 -0.2137780535 9.744620e-02 -0.0439313764
2725 O00469 PLOD2 0.3939850317 1.365480e-01 -0.0665084542
2726 Q13404 UBE2V1 -0.0007615578 9.982756e-01 0.0468917361
2727 Q10713 PMPCA -0.5635984037 2.499798e-05 0.0550121724
2728 Q9NZM1 MYOF 0.2590918498 7.374383e-01 0.0598254527
2729 P08236 GUSB 0.2294336255 1.048175e-01 0.0523026752
2730 P17900 GM2A -0.3534298821 3.298585e-01 -0.0714124070
2731 O75116 ROCK2 0.1529708576 3.931930e-01 -0.2522418974
2732 Q9UBS4 DNAJB11 -0.1192728397 6.626186e-01 0.0511029395
2733 P49736 MCM2 2.5137351365 1.527253e-10 -0.1170023987
2734 P57679 EVC 0.2274242440 5.590541e-01 -0.1775980741
2735 P46013 MKI67 3.1925555339 4.277678e-09 -0.0818400961
2736 Q96TC7 RMDN3 -0.4889222680 8.230405e-02 0.0592588068
2737 Q5J8M3 EMC4 -0.0571915661 7.186727e-01 0.0322312379
2738 Q6NZI2 CAVIN1 -0.4143890508 9.599098e-02 -0.0581681850
2739 O43447 PPIH 1.1325713088 3.903568e-07 -0.0539035288
2740 Q9HCU5 PREB -0.3227376633 5.862226e-03 -0.0510941370
2741 P49591 SARS1 -1.0527251109 1.577502e-08 0.1073736212
2742 Q15125 EBP 0.4399490328 6.579634e-02 0.0435468627
2743 P40763 STAT3 -1.0243533136 2.139961e-05 0.0447656245
2744 P13611 VCAN 0.1345961284 7.373560e-01 -0.0508078233
2745 P19022 CDH2 1.0229789347 3.472860e-06 -0.0519210903
2746 Q7Z333 SETX 0.2847320717 1.284597e-01 -0.1004294542
2747 Q9NZC3 GDE1 -0.3856784333 4.123132e-02 0.0570080442
2748 Q13424 SNTA1 0.3364184108 4.081515e-01 0.0412656794
2749 Q9H2V7 SPNS1 -0.1917477773 3.157111e-01 -0.0635085952
2750 Q5SWX8 ODR4 0.1316054818 3.830812e-01 0.0953584047
2751 P11169 SLC2A3 0.3337652162 3.138746e-01 -0.1080010260
2752 Q15942 ZYX -0.0014679632 9.962108e-01 0.0622000068
2753 Q86WV6 STING1 -0.8053645358 8.061501e-02 0.1072970854
2754 P48449 LSS 0.8975821584 3.491184e-06 0.0356129336
2755 Q9BV73 CEP250 -0.3598995582 1.506746e-01 -0.0596036872
2756 Q92782 DPF1 1.9951502499 7.472775e-08 0.0576145448
2757 Q13033 STRN3 -0.0690902368 7.368047e-01 0.0352323755
2758 P17301 ITGA2 -0.6592482313 3.355090e-01 0.1003710135
2759 Q15293 RCN1 0.0734770925 8.662738e-01 0.0628197111
2760 P53701 HCCS -0.0867614590 5.480628e-01 -0.0484273888
2761 Q9UKS6 PACSIN3 -0.5272179865 8.845802e-02 -0.1094987063
2762 Q07955 SRSF1 1.1467374695 5.346559e-07 -0.0391859015
2763 Q7L592 NDUFAF7 -0.2633960486 1.182386e-01 -0.0404932725
2764 P33316 DUT 0.6312258784 3.413888e-02 0.0774810686
2765 Q05519 SRSF11 0.1190336337 4.799253e-01 0.0569071921
2766 Q9UNZ2 NSFL1C 0.2955679637 1.963230e-02 0.0592351024
2767 O95208 EPN2 0.3143992197 1.025879e-01 0.0382845970
2768 Q99615 DNAJC7 0.3290536994 3.051566e-03 -0.0676349976
2769 P11217 PYGM 1.1700866775 4.925563e-04 0.0598227514
2770 Q8N1G2 CMTR1 0.1603182047 1.682034e-01 0.0819301533
2771 O75306 NDUFS2 0.2880903396 1.178153e-01 0.0399446084
2772 Q99426 TBCB 0.6548047592 7.473858e-04 0.0986086617
2773 Q5W111 SPRYD7 -0.4229806633 2.582381e-04 -0.0523072823
2774 Q9NP81 SARS2 1.0214661726 4.101962e-06 -0.0444664870
2775 Q9HDC5 JPH1 -0.1280236647 6.192886e-01 0.2317496612
2776 Q9UJC3 HOOK1 1.1753749079 8.509754e-04 0.0940526189
2777 Q92506 HSD17B8 -0.3905828587 1.022885e-01 -0.0712989662
2778 P11234 RALB -1.0172204118 7.529379e-07 -0.0403100190
2779 Q99623 PHB2 0.5099329422 1.705015e-03 -0.0514729501
2780 P53985 SLC16A1 0.5892047325 7.591981e-02 0.0438739194
2781 P55795 HNRNPH2 -0.1209912621 6.382475e-01 0.0350025774
2782 O14974 PPP1R12A -0.0877030419 6.815455e-01 0.0453489137
2783 P09936 UCHL1 -0.3399545366 6.273533e-01 0.0904408042
2784 Q96KP1 EXOC2 0.4330945960 1.761561e-02 0.0945528203
2785 P30040 ERP29 0.0508678515 8.112169e-01 -0.0465198501
2786 Q96EP5 DAZAP1 0.7609342008 2.812139e-06 -0.0369992686
2787 Q9P0I2 EMC3 -0.2996132352 6.588620e-02 0.0366126282
2788 Q9Y235 APOBEC2 -0.9052056042 1.473419e-01 0.0583786774
2789 O15400 STX7 0.3354591695 3.350851e-02 -0.0344998618
2790 Q13144 EIF2B5 0.2531519590 3.449055e-02 0.0433398568
2791 O75147 OBSL1 0.4335231822 1.971177e-01 0.0577891854
2792 Q12789 GTF3C1 -0.2615329182 3.133200e-01 -0.0640506438
2793 P42167 TMPO 0.7237111156 1.412195e-03 -0.0375140209
2794 O00231 PSMD11 0.1317317300 4.084242e-01 0.0375918482
2795 Q9Y3D2 MSRB2 -0.0517416376 8.738745e-01 0.0586541092
2796 Q8IVS2 MCAT -0.2926567365 9.613072e-02 -0.1014839470
2797 Q9H3H5 DPAGT1 0.4086802317 1.157844e-01 0.0427259471
2798 Q5TGZ0 MICOS10 0.1068775129 6.606668e-01 -0.0447177365
2799 Q8N5N7 MRPL50 0.2385118249 1.950985e-01 0.0925113632
2800 P42166 TMPO 0.7237111156 1.412195e-03 0.0630164041
2801 P62318 SNRPD3 0.2561489101 1.719657e-02 0.1150055434
2802 P35222 CTNNB1 -0.3135098953 5.573547e-02 0.0446602174
2803 Q9UM22 EPDR1 -0.1849868484 6.122030e-01 0.0881448434
2804 P21912 SDHB 0.5052465843 4.003952e-02 0.0336121763
2805 P61106 RAB14 -0.6061920095 6.679032e-06 -0.0482372598
2806 Q9BWS9 CHID1 0.0771900662 6.203558e-01 0.0553802355
2807 Q9UL25 RAB21 -0.5980758710 1.749916e-03 -0.0353052471
2808 Q8NDY3 ADPRHL1 1.6004304321 1.136792e-04 0.0537533243
2809 Q9Y4W6 AFG3L2 0.9546075105 3.305842e-09 0.0341604126
2810 Q9NQC3 RTN4 0.4550297070 5.150134e-03 -0.0482728158
2811 Q9H074 PAIP1 0.4366179687 4.251179e-04 -0.1140952414
2812 Q10471 GALNT2 -0.2016125277 6.685165e-01 0.0649653054
2813 Q9BPW8 NIPSNAP1 0.9220238580 1.273560e-03 -0.0384468594
2814 Q9HC36 MRM3 0.3965624087 4.552754e-02 0.0546904084
2815 P52292 KPNA2 0.8046923564 1.648005e-04 0.0497956870
2816 P15586 GNS -0.2958473758 2.518025e-01 0.0306316731
2817 O75352 MPDU1 0.3227422935 2.134996e-01 0.0468059691
2818 O15061 SYNM -1.1301308435 1.964901e-06 -0.0817377103
2819 Q9Y6K0 CEPT1 -0.7299724718 7.499442e-05 -0.0787014303
2820 P08069 IGF1R -0.7116650541 3.449183e-04 -0.0689514183
2821 O00562 PITPNM1 -0.2555296692 4.094867e-01 0.1285049043
2822 Q14978 NOLC1 0.0941669401 6.831750e-01 -0.0428509657
2823 Q9H9P8 L2HGDH 1.1148373528 2.186165e-07 0.0587676775
2824 Q9UIW2 PLXNA1 0.5527794006 3.662538e-02 -0.0387004284
2825 Q8NHH9 ATL2 0.2186443478 2.227770e-01 -0.0547411172
2826 Q9BV38 WDR18 1.0320014546 9.827105e-05 -0.0477595397
2827 P52948 NUP98 0.4585014024 1.016122e-04 -0.0377301892
2828 Q7Z4V5 HDGFL2 -0.0309362072 8.351643e-01 0.0444152867
2829 Q9UMS6 SYNPO2 2.0191382577 8.842194e-04 0.0762101842
2830 Q8NE86 MCU 0.0919034848 7.318300e-01 -0.0610622846
2831 O14828 SCAMP3 0.8991398890 6.266594e-06 -0.0586641523
2832 Q15382 RHEB -0.3164275823 9.554793e-02 0.0980563155
2833 Q9H0Q3 FXYD6 0.8701441681 2.026593e-01 -0.0890873295
2834 Q9UPN6 SCAF8 -0.1929916183 2.928622e-01 0.0757156842
2835 P38435 GGCX -0.1847947804 4.394869e-01 -0.0977452700
2836 P04844 RPN2 -0.1306212037 5.687116e-01 0.0382036593
2837 O75923 DYSF 1.1621227104 1.600570e-06 0.0384468794
2838 P43307 SSR1 0.2111926133 5.063750e-01 -0.0386476726
2839 P48426 PIP4K2A -1.0699081860 2.290935e-05 0.0815168067
2840 P49903 SEPHS1 0.4702161666 2.673273e-04 0.0766595914
2841 Q86SX6 GLRX5 0.2013957932 2.053194e-01 -0.0952910019
2842 P54727 RAD23B 0.0633134843 6.185586e-01 0.0349093765
2843 Q96C01 FAM136A 0.6096478093 1.314144e-03 -0.0467326244
2844 P12081 HARS1 0.1437977121 4.130152e-01 -0.0453891068
2845 Q9H6X2 ANTXR1 0.0498977738 8.443521e-01 -0.0920511319
2846 Q9Y672 ALG6 0.4433937328 1.714454e-01 0.1066017201
2847 Q7Z3D6 DGLUCY 0.9247290692 1.051245e-03 -0.2631853628
2848 Q12841 FSTL1 -0.0010329937 9.984980e-01 -0.0922538851
2849 P68036 UBE2L3 -0.0134667438 9.082355e-01 0.0570999245
2850 Q9NVV0 TMEM38B 0.2517104597 5.219035e-01 -0.0675819583
2851 Q6UW02 CYP20A1 -0.0644544560 6.820543e-01 -0.1041480335
2852 P46379 BAG6 0.3581078598 5.985753e-03 -0.0524820295
2853 P50991 CCT4 -0.0156253035 9.285961e-01 0.0517182399
2854 O15427 SLC16A3 0.1013201229 8.698396e-01 -0.0627494545
2855 P49721 PSMB2 0.1736474882 2.222727e-01 -0.0587442742
2856 O95490 ADGRL2 -0.1020226040 6.002582e-01 0.0609834445
2857 P50995 ANXA11 -0.2453330962 4.428612e-01 -0.0623106737
2858 Q9NRD8 DUOX2 -4.1202038448 1.002301e-05 0.0631037482
2859 Q15020 SART3 -0.0625391404 7.398659e-01 0.0429271374
2860 P49590 HARS2 0.4994461191 7.250382e-03 -0.0346749937
2861 Q7KZN9 COX15 -0.2930529375 3.579409e-03 0.0440658440
2862 Q9UHK6 AMACR 1.3043917794 1.797816e-03 -0.0735248336
2863 Q4ZIN3 TMEM259 -0.2273601374 1.977664e-01 0.0535062995
2864 Q96ED9 HOOK2 0.1975435921 6.382631e-01 -0.0590927216
2865 Q5TZA2 CROCC -1.1006844648 5.905056e-03 0.0767071421
2866 Q86TM6 SYVN1 -0.3880618122 1.256510e-01 0.0459224259
2867 P08962 CD63 0.0150629990 9.623440e-01 0.0770717857
2868 Q9UNM6 PSMD13 -0.5066445167 3.723469e-06 0.0316437552
2869 O95363 FARS2 0.5535626148 2.439788e-03 -0.0690304728
2870 Q92581 SLC9A6 0.5113228175 1.388297e-02 0.0702929967
2871 O00161 SNAP23 0.6303111960 6.560196e-02 0.0437024141
2872 P68402 PAFAH1B2 -0.2886264239 1.301005e-01 0.0625850587
2873 Q99797 MIPEP 0.1256705484 4.966359e-01 -0.0511739415
2874 P51571 SSR4 -0.1835340581 3.544101e-01 -0.0441070358
2875 Q7Z460 CLASP1 0.3337851121 8.710299e-02 -0.0518114110
2876 P20338 RAB4A 0.1765960218 3.922651e-01 0.0465858671
2877 Q14241 ELOA -0.4092187949 8.578736e-04 0.0515293974
2878 P25685 DNAJB1 0.0796660234 6.446858e-01 -0.0271807257
2879 Q99733 NAP1L4 -0.3769014802 3.533737e-04 -0.0469481717
2880 P49585 PCYT1A -0.0301102915 8.784290e-01 0.1541059672
2881 Q8N6M3 FITM2 0.9694399260 4.442482e-03 0.0357752799
2882 Q14554 PDIA5 0.0186104793 9.764407e-01 0.0348707433
2883 Q99729 HNRNPAB -0.6763190330 5.374784e-04 0.0409336737
2884 Q9UKR5 ERG28 1.1097841817 1.122309e-06 -0.0962221993
2885 Q6UXH1 CRELD2 -0.0948733189 7.962517e-01 0.0965664343
2886 P12931 SRC -1.3712317108 7.722022e-06 0.0407092704
2887 P08237 PFKM 1.4935116688 1.210313e-06 -0.0898612605
2888 Q01484 ANK2 1.7939950354 8.866739e-09 0.0272193144
2889 Q9NRX4 PHPT1 -0.7349230853 6.783380e-03 0.1202582430
2890 O60488 ACSL4 -0.0552859542 8.688927e-01 0.0473513869
2891 Q9ULH0 KIDINS220 0.2402749428 1.643516e-01 -0.0328930357
2892 P23141 CES1 0.6945623858 8.736288e-01 0.1630179495
2893 Q5T160 RARS2 -0.0981851020 6.179473e-01 0.0919742209
2894 P49419 ALDH7A1 0.2759755526 2.970574e-01 0.0264597337
2895 Q96A35 MRPL24 0.8250328709 1.456717e-05 0.0399831462
2896 Q92879 CELF1 -0.3073608827 2.150925e-02 -0.1024579295
2897 O15127 SCAMP2 0.2396260245 9.852726e-02 -0.0324583556
2898 P24534 EEF1B2 -0.2127318204 1.537205e-01 0.0376215225
2899 Q99714 HSD17B10 -0.0669239898 7.571384e-01 0.0336276297
2900 P33121 ACSL1 -0.6970208124 9.547417e-05 0.0614585272
2901 O75251 NDUFS7 0.3535741567 2.407003e-01 0.0287078657
2902 Q7L311 ARMCX2 1.8973023053 3.327111e-10 0.0481945613
2903 Q9NUL3 STAU2 0.0131930846 9.462116e-01 -0.0377401765
2904 Q99567 NUP88 0.3971294141 1.633437e-03 0.0516413103
2905 Q96S97 MYADM 1.5499982440 4.850498e-08 -0.0294306152
2906 Q53H82 LACTB2 -0.8935615934 1.078156e-06 0.0838942441
2907 P61970 NUTF2 -0.0748784852 6.682603e-01 0.0347417475
2908 Q7KYR7 BTN2A1 0.2873014354 2.533183e-01 -0.0365146529
2909 Q9Y5Y5 PEX16 -0.6684280247 5.083541e-05 -0.0471252563
2910 Q9NX40 OCIAD1 -0.1469789802 3.105960e-01 -0.0329535853
2911 O76041 NEBL 1.3297566443 1.144136e-04 -0.0339931053
2912 Q92785 DPF2 -0.6879058448 5.208639e-04 -0.1388608274
2913 P41250 GARS1 0.8619748361 6.728452e-05 0.0671563567
2914 Q14332 FZD2 1.4730566556 1.199648e-07 -0.0458899048
2915 P21953 BCKDHB 0.3133160340 3.763684e-02 -0.0554461002
2916 Q8WUY8 NAT14 0.8536008659 3.181297e-04 -0.0268740309
2917 Q6UVK1 CSPG4 -2.2982710161 6.625095e-05 0.0655424195
2918 P60903 S100A10 -0.2551527683 6.924834e-01 -0.0458432780
2919 Q6KC79 NIPBL 0.3087974361 1.787737e-02 0.0367659292
2920 Q7KZI7 MARK2 -0.0457171413 7.466869e-01 0.0480489442
2921 O43172 PRPF4 -0.0809936850 6.507105e-01 -0.0372325420
2922 Q8NHP6 MOSPD2 -0.4707672151 1.301717e-01 -0.0877578602
2923 Q86YP4 GATAD2A -0.1701517434 4.384734e-01 -0.0510996736
2924 O60476 MAN1A2 0.3391328573 1.234174e-02 -0.0245294283
2925 O15031 PLXNB2 -0.8812962608 3.598989e-03 -0.0265972718
2926 Q9Y5U8 MPC1 1.5352718248 3.271239e-04 0.0329559961
2927 Q8NFF5 FLAD1 -0.4391096098 1.658847e-03 0.0423090757
2928 Q9BZE1 MRPL37 -0.1088503690 4.340233e-01 -0.0272307953
2929 Q99959 PKP2 0.5908823609 2.229208e-03 -0.0431539448
2930 Q9BY44 EIF2A -0.2529319925 1.090653e-01 -0.0588306792
2931 P51812 RPS6KA3 -0.5160511858 7.178237e-02 -0.1351357707
2932 O60885 BRD4 -0.1896562194 2.819238e-01 -0.0268679220
2933 Q6DD88 ATL3 0.1778359666 7.055532e-01 0.0526935539
2934 Q96T60 PNKP 0.2889479929 5.830660e-03 0.0457296192
2935 P42892 ECE1 -0.7328690188 4.039544e-02 -0.0420162753
2936 Q9NPJ3 ACOT13 0.5659913885 5.808184e-03 -0.0226461076
2937 Q8N442 GUF1 -0.4627736790 2.908206e-03 0.0642603869
2938 Q8IXL7 MSRB3 1.2172022551 3.086585e-08 -0.0556078094
2939 Q6ZT12 UBR3 0.1760618267 4.091701e-01 0.0300423740
2940 Q99808 SLC29A1 0.2987470523 2.640764e-01 0.0874593754
2941 Q9P2I0 CPSF2 0.0571515581 7.962114e-01 -0.0879946763
2942 P28827 PTPRM 0.1917169328 3.458209e-01 -0.0331786696
2943 Q9NVA1 UQCC1 -0.3507511332 1.998292e-02 -0.0340033995
2944 Q9BZG1 RAB34 0.4474600346 1.284409e-02 0.0508239569
2945 Q9Y3E5 PTRH2 0.0012722096 9.951722e-01 0.0645852521
2946 Q9P2K3 RCOR3 0.2524331758 2.221760e-01 0.0392585124
2947 Q99627 COPS8 -0.2659476261 2.590406e-02 0.0349591146
2948 P12956 XRCC6 -0.2232203727 7.866292e-02 -0.0256959162
2949 Q9UHD9 UBQLN2 0.4515462663 6.169912e-03 -0.0272603802
2950 Q16630 CPSF6 0.2000872512 7.758310e-02 -0.0240807929
2951 Q15172 PPP2R5A 0.5067013570 9.406655e-02 0.0631589618
2952 Q13418 ILK 0.9473400948 1.244212e-04 0.0345000810
2953 Q02641 CACNB1 1.9195037129 9.739369e-07 -0.0592226725
2954 Q86WA6 BPHL 0.5707764251 3.152536e-02 -0.0518002257
2955 Q12769 NUP160 0.7710263291 9.436648e-08 0.0406688623
2956 Q14011 CIRBP -1.1407725749 3.107872e-06 -0.0414076139
2957 P08579 SNRPB2 -0.1572061897 2.036525e-01 -0.0391390556
2958 Q9Y6A9 SPCS1 0.1690266648 1.851494e-01 0.0359485719
2959 P32189 GK 0.3606583800 4.827493e-01 0.0433016068
2960 Q9BU61 NDUFAF3 0.1114685464 5.592804e-01 -0.0346113474
2961 Q8NI37 PPTC7 0.0438384796 8.588064e-01 -0.0373320338
2962 O43707 ACTN4 -0.4761080147 4.266202e-01 0.0777883145
2963 P49588 AARS1 1.5841070552 6.467535e-09 0.0890582812
2964 Q15907 RAB11B 0.4795082111 2.439736e-02 0.0257816639
2965 Q9BZE4 GTPBP4 -0.2988125487 3.856018e-02 -0.0498385332
2966 Q96EY7 PTCD3 0.6391311044 1.736612e-03 -0.0248277728
2967 Q96BI1 SLC22A18 1.4737032602 4.801212e-06 -0.0359401402
2968 Q9UBC2 EPS15L1 0.2133944917 1.693419e-01 -0.0279279655
2969 Q96HC4 PDLIM5 1.2523781031 4.023588e-06 -0.0248868539
2970 Q8N2U0 TMEM256 0.6431733357 2.481525e-02 0.0322142413
2971 P50336 PPOX 1.0147511388 1.940429e-05 0.0460942490
2972 P55268 LAMB2 0.2994478987 4.049431e-01 0.0512589339
2973 Q07065 CKAP4 0.2290019241 5.619301e-01 0.0339764070
2974 Q9Y4F5 CEP170B -1.8261592828 1.011517e-09 0.0376916941
2975 P25490 YY1 -0.6359075407 1.642571e-06 0.0898810561
2976 Q15334 LLGL1 -0.5192386417 4.128438e-03 0.0547027133
2977 O75094 SLIT3 1.4134005456 5.792407e-05 -0.1671000127
2978 Q13061 TRDN 0.9233678722 2.516266e-03 -0.0403187385
2979 Q9Y3B3 TMED7 0.0187024262 9.297143e-01 -0.0350062646
2980 Q9BV10 ALG12 0.6429692943 2.560487e-04 0.0327413818
2981 Q9HAU0 PLEKHA5 0.3347440682 2.250581e-01 -0.0266480630
2982 O60831 PRAF2 -0.0151365017 9.621687e-01 -0.0370789890
2983 Q9P253 VPS18 0.0742694706 7.132751e-01 -0.0529451039
2984 P05161 ISG15 -1.5702937459 1.524907e-05 0.0669276535
2985 Q8IUR5 TMTC1 -0.1437311405 7.572866e-01 -0.0396019266
2986 Q5TEU4 NDUFAF5 0.6492995017 6.676116e-03 -0.0289994717
2987 P49720 PSMB3 -0.0288951918 8.800350e-01 0.0293139657
2988 P61803 DAD1 0.4229397466 6.178350e-02 0.0397682481
2989 Q969N2 PIGT -0.2282905765 2.446822e-01 0.0244231043
2990 O95563 MPC2 0.1432933277 7.056427e-01 0.0245607177
2991 Q15796 SMAD2 -0.1048940620 4.897474e-01 0.0533082365
2992 P08574 CYC1 0.6622068989 2.042507e-02 0.0236360400
2993 Q13363 CTBP1 -0.2228051809 1.013186e-01 -0.0282297751
2994 Q96MR6 CFAP57 -1.3049954676 2.723012e-02 -0.0626455125
2995 P05787 KRT8 -0.7728995409 1.526432e-02 0.0401858350
2996 Q14118 DAG1 0.5142330967 3.137162e-03 0.0245662429
2997 Q9UIA9 XPO7 0.6699559639 1.983530e-05 0.0587230586
2998 P48047 ATP5PO 0.9503223957 8.897693e-03 -0.0270509250
2999 Q99523 SORT1 0.5347403952 1.924261e-02 -0.0405566479
3000 P12955 PEPD -0.0952042460 5.809760e-01 -0.2413330960
3001 P35221 CTNNA1 -0.2327434255 1.767331e-01 -0.0226633349
3002 Q9Y2Z4 YARS2 -0.0822160346 5.310203e-01 0.0282054454
3003 Q9NPH0 ACP6 0.8323731478 8.348710e-04 -0.0532582391
3004 Q8TCT9 HM13 -0.2385395131 3.756555e-01 -0.0348934272
3005 Q9BVG9 PTDSS2 0.3333820081 6.978137e-02 -0.0535673994
3006 Q05682 CALD1 -0.2955914500 5.644595e-01 0.0850223075
3007 P51149 RAB7A -0.9730000611 4.807184e-10 0.0233836508
3008 A6NHR9 SMCHD1 0.4262820303 7.151271e-03 -0.0269693090
3009 P29317 EPHA2 -1.6695042973 2.253533e-06 0.0427380340
3010 Q01973 ROR1 1.0458692713 1.745846e-06 0.0332207465
3011 Q16854 DGUOK -0.0663695406 6.878724e-01 -0.0222537186
3012 O00754 MAN2B1 -0.2076259025 3.117371e-01 0.0261289337
3013 P31946 YWHAB -0.2709485083 5.696446e-02 0.0490402257
3014 Q5RI15 COX20 -0.0789223383 8.457300e-01 -0.0429324298
3015 P59998 ARPC4 -0.1166324386 5.897208e-01 -0.0244967284
3016 P62877 RBX1 0.2218513691 4.439880e-01 -0.0874966282
3017 O15042 U2SURP -0.0161047360 9.276878e-01 -0.0297552513
3018 P49773 HINT1 -0.1379516169 6.318629e-01 -0.0341436443
3019 Q96I59 NARS2 1.0166316559 7.143620e-07 -0.0574236054
3020 P22102 GART 0.7042133520 2.834512e-06 -0.0467881274
3021 P30536 TSPO 0.6316748503 8.172379e-02 -0.0411662269
3022 Q7L1Q6 BZW1 -0.7628026509 3.260348e-04 0.0292095329
3023 Q6YP21 KYAT3 0.2018132983 6.613060e-01 0.0314756211
3024 Q6PI78 TMEM65 0.1878647364 6.636985e-01 0.0195001860
3025 Q13332 PTPRS 0.8745648238 2.123910e-04 0.0545269636
3026 Q8TBP6 SLC25A40 1.9401236779 6.001086e-07 -0.0390977985
3027 Q01105 SET 0.2092224347 4.810934e-02 0.0270707888
3028 P35232 PHB1 0.1900217351 1.817125e-01 0.0224839973
3029 Q9Y6I9 TEX264 -0.7453207723 8.456383e-05 -0.0483702150
3030 P21439 ABCB4 1.0203498263 2.425988e-01 -0.0497880231
3031 Q92973 TNPO1 -0.4401618813 1.315258e-02 0.0198726779
3032 Q9BVV7 TIMM21 -1.1822153430 1.712730e-04 -0.0313154583
3033 O95819 MAP4K4 -0.1144830644 4.857575e-01 0.0156849053
3034 Q9BYF1 ACE2 -0.5906885614 3.816490e-01 0.0793961049
3035 P67870 CSNK2B -0.6984376508 3.070101e-06 0.0288732120
3036 Q9NVD7 PARVA 0.1355749274 5.577359e-01 0.0277182598
3037 P61457 PCBD1 0.4464298248 2.985501e-02 -0.0361964573
3038 Q9BZQ8 NIBAN1 0.9002107348 7.886595e-04 0.0323376874
3039 P35606 COPB2 -0.1909621281 1.036602e-01 -0.0190123058
3040 A3KMH1 VWA8 0.7370869846 5.651123e-05 -0.0221940140
3041 O14874 BCKDK 0.8028773547 2.292041e-04 -0.0170291362
3042 O95299 NDUFA10 -0.1924235477 4.360624e-01 0.0211530589
3043 Q9Y276 BCS1L 0.7675384836 3.652432e-05 0.0253138668
3044 Q14847 LASP1 -0.3395179292 6.075453e-01 -0.0317330085
3045 Q96J01 THOC3 -0.4925124653 2.576464e-02 0.0929392667
3046 P54886 ALDH18A1 1.5203887598 1.204440e-04 -0.0283503541
3047 Q13825 AUH 0.5042923593 3.105908e-02 -0.0180057037
3048 Q9BX67 JAM3 -0.1149739721 7.610126e-01 -0.0213181168
3049 Q9UDW1 UQCR10 0.1886420584 5.456970e-01 0.0192508077
3050 Q8TDJ6 DMXL2 1.3506583196 3.166466e-15 -0.0248687885
3051 Q9Y646 CPQ 0.5196928857 2.021832e-01 -0.0294486905
3052 Q14318 FKBP8 0.2709802649 1.364889e-01 0.0215599964
3053 O15235 MRPS12 0.2728127491 2.836779e-01 0.0235231716
3054 Q9UHN1 POLG2 -0.5267479553 7.661430e-02 -0.0373910423
3055 Q9UI09 NDUFA12 0.5807364513 8.969901e-03 0.0157184413
3056 Q8TBZ3 WDR20 -0.1072198058 6.340491e-01 -0.0671657219
3057 O00746 NME4 1.3230825523 1.076972e-05 0.0320260883
3058 Q15120 PDK3 0.6832118736 2.326997e-01 -0.0235780431
3059 P49754 VPS41 -0.3423971669 6.198518e-03 0.0303422242
3060 O95573 ACSL3 -0.2917174664 7.251713e-02 -0.0221728864
3061 Q8N1G4 LRRC47 -0.2350751143 5.825127e-02 0.0210580657
3062 Q9H9S3 SEC61A2 0.0811316469 6.871579e-01 0.0226494604
3063 P26678 PLN 0.9085794685 8.822501e-02 0.0288374328
3064 Q15392 DHCR24 -0.4128370052 1.646866e-01 -0.0205230860
3065 P13010 XRCC5 0.3662608081 9.610921e-04 -0.0175731941
3066 Q00587 CDC42EP1 -0.8916197699 5.297725e-02 -0.0752537272
3067 Q09666 AHNAK -0.8094230465 1.545179e-02 0.0217256269
3068 Q86SQ0 PHLDB2 1.5240233272 5.490183e-07 -0.0441724106
3069 P50416 CPT1A 0.3146585067 3.191955e-01 -0.0341154233
3070 Q0VGL1 LAMTOR4 -0.2956669260 2.789261e-01 0.0151409905
3071 O75475 PSIP1 -0.6116497229 1.997567e-02 0.0809429909
3072 P01023 A2M -0.7826268095 1.230949e-01 -0.0377802819
3073 Q9ULV4 CORO1C 0.2308388730 6.717477e-01 0.0182228719
3074 P35270 SPR 0.2069392158 3.390036e-01 0.0234553186
3075 P02545 LMNA -1.0291014417 2.898158e-06 0.0158073427
3076 P61421 ATP6V0D1 -0.7736694316 9.987902e-07 -0.0242455672
3077 P20340 RAB6A -0.1669417704 2.294615e-01 0.0176739001
3078 Q9BQA9 CYBC1 -0.8605151337 7.964658e-05 0.0170455743
3079 P25789 PSMA4 0.5185961726 2.026085e-02 -0.0140235078
3080 Q9BXW7 HDHD5 1.2701830353 6.374369e-04 -0.0197262338
3081 Q9UKE5 TNIK 0.4456476235 4.089605e-02 0.0164577249
3082 O94973 AP2A2 0.1869421876 2.482114e-01 -0.0197305999
3083 Q96MW7 TIGD1 0.3470743383 1.691772e-01 -0.0346474874
3084 P57105 SYNJ2BP 0.3761689012 2.160368e-03 0.0161700546
3085 P61009 SPCS3 0.1167641931 7.723840e-01 -0.0137165968
3086 Q9H2H9 SLC38A1 0.0647609380 8.505765e-01 -0.0305677796
3087 Q9H6E4 CCDC134 0.2430253768 1.880425e-01 0.0525545575
3088 Q8NE71 ABCF1 0.0790685762 6.374981e-01 -0.0329983701
3089 Q9NZN4 EHD2 1.6030370855 9.996433e-02 -0.0441618003
3090 Q8TEM1 NUP210 0.5104588892 6.900597e-02 0.0200278664
3091 O43819 SCO2 -0.0471844268 9.026241e-01 -0.0195882447
3092 Q12846 STX4 0.3378154127 1.499675e-02 -0.0173400663
3093 P07355 ANXA2 -0.2026905667 6.951234e-01 0.0282842760
3094 Q6P0N0 MIS18BP1 2.7518481437 1.082586e-10 0.0204778709
3095 Q6P1M3 LLGL2 -0.5150639949 2.034917e-02 0.0223517389
3096 Q13177 PAK2 -0.6036129385 2.943655e-03 0.0251638166
3097 Q9Y4G6 TLN2 0.9349376081 4.886475e-03 0.0148237056
3098 O75907 DGAT1 0.2234994147 1.978209e-01 0.0342642041
3099 P47897 QARS1 0.2938181134 2.984274e-02 -0.0160481348
3100 P63000 RAC1 -0.2137928968 1.858278e-01 0.0191741341
3101 Q96G01 BICD1 -0.3388426676 2.133358e-01 0.0344546541
3102 Q9NTK5 OLA1 0.7241822759 6.861437e-06 0.0268868800
3103 Q86UP2 KTN1 0.1780880035 3.197922e-01 -0.0140971525
3104 O95479 H6PD 0.1099685925 6.512518e-01 -0.0149775013
3105 P30084 ECHS1 0.0168521672 9.291116e-01 0.0136627494
3106 Q9NRV9 HEBP1 -0.5132258586 9.516790e-03 0.0285287161
3107 P62805 H4C8 -2.7245675048 7.519319e-11 0.0194275477
3108 P62805 H4C5 -2.9527234766 2.207268e-07 0.0194275477
3109 P62805 H4C15 -2.2859726782 5.044427e-11 0.0194275477
3110 P62805 H4C14 -2.0606580779 1.773268e-08 0.0194275477
3111 P10301 RRAS 0.1390198776 7.458194e-01 0.0196646958
3112 O43684 BUB3 -0.1754186697 3.296098e-01 -0.0140960751
3113 Q14155 ARHGEF7 -0.1409333665 3.767675e-01 -0.0700116742
3114 Q8TD19 NEK9 -0.2515666216 4.741768e-01 0.0582896964
3115 O14958 CASQ2 0.3476369101 6.032927e-01 -0.0365787285
3116 Q15560 TCEA2 0.5014046138 3.991481e-02 -0.0373465566
3117 Q9Y6N5 SQOR 0.1397066292 8.236833e-01 -0.0502072562
3118 O76003 GLRX3 0.0548451172 8.412810e-01 0.0217527662
3119 Q9BR39 JPH2 1.3996598205 4.118762e-06 -0.0100676478
3120 Q5TAQ9 DCAF8 0.0640316982 7.077788e-01 0.0318414456
3121 Q96E39 RBMXL1 0.3229307715 2.700938e-02 0.0312585100
3122 P61204 ARF3 -0.4700240365 1.589026e-02 -0.0112127960
3123 Q14934 NFATC4 -0.4328217777 3.813405e-02 -0.0184688461
3124 Q15005 SPCS2 0.5138570794 4.040089e-04 0.0124065929
3125 Q9C0D9 SELENOI 0.0956465108 7.108595e-01 0.0296622413
3126 Q9Y320 TMX2 0.5081431072 9.349774e-04 0.0119171151
3127 P11498 PC -0.1279676899 6.192951e-01 0.0339686151
3128 O60763 USO1 0.1767036449 1.186142e-01 -0.0139831853
3129 P33993 MCM7 1.6226689175 8.792193e-07 0.0296264221
3130 Q86VU5 COMTD1 0.3015082903 3.842097e-01 -0.0246204336
3131 P35998 PSMC2 0.0231186175 8.944290e-01 -0.0100998261
3132 O75369 FLNB -0.0988592747 9.144939e-01 -0.0491792455
3133 Q9P2R3 ANKFY1 -0.2411544325 1.167302e-01 -0.0160556032
3134 P20618 PSMB1 0.3643194792 7.400782e-02 0.0094208407
3135 Q5XKP0 MICOS13 0.4489559445 1.169351e-01 0.0182047101
3136 P51809 VAMP7 -0.3296392471 5.366326e-02 0.0184585233
3137 O15228 GNPAT 0.5005834735 3.422489e-03 -0.0163471219
3138 P46939 UTRN 0.4003524332 2.914426e-02 0.0183565192
3139 P09382 LGALS1 0.4366035639 5.617892e-01 -0.0307928569
3140 P27694 RPA1 -0.3150572590 7.233654e-02 0.0277877963
3141 O00462 MANBA 0.2662210358 3.998225e-01 -0.0097998990
3142 P22307 SCP2 0.2471783199 3.591419e-01 -0.0145158437
3143 Q9NZM3 ITSN2 0.3906259040 2.459316e-02 0.0221290468
3144 P34931 HSPA1L -0.1067583432 7.947659e-01 -0.0198052635
3145 P16219 ACADS 0.4397877130 1.742002e-01 -0.0142894513
3146 Q9BS26 ERP44 0.6267901797 1.141002e-05 0.0118885102
3147 Q14974 KPNB1 0.9432231406 7.270882e-10 0.0091638057
3148 Q9UN42 ATP1B4 0.7789519298 5.729877e-01 0.0529851700
3149 P50402 EMD -0.1146204067 5.251555e-01 -0.0092716097
3150 P01112 HRAS -1.3080030120 7.714755e-08 0.0135000733
3151 Q9NUM4 TMEM106B 0.9923341901 2.604878e-05 0.0223334393
3152 Q9BWM7 SFXN3 0.5876231794 2.824172e-01 0.0217927237
3153 Q969M1 TOMM40L 1.2197492234 1.149390e-05 0.0210633620
3154 P05166 PCCB 0.1026136481 4.873153e-01 0.0107373080
3155 Q8N2H3 PYROXD2 0.0147736392 9.855048e-01 0.0407270612
3156 P46060 RANGAP1 -0.0845947963 6.817385e-01 0.0101036945
3157 P24043 LAMA2 0.6610700824 2.990604e-01 -0.0286933388
3158 P13051 UNG 1.1137115328 1.077001e-07 -0.0239032109
3159 Q02252 ALDH6A1 0.1345489239 6.551229e-01 0.0114156845
3160 Q8NFH5 NUP35 1.2799588222 2.700240e-08 -0.0086793530
3161 Q9UBM7 DHCR7 1.0892388385 1.358450e-02 0.0265568097
3162 Q9NVT9 ARMC1 0.0866637493 6.250554e-01 -0.0695866795
3163 Q15691 MAPRE1 -0.6423155724 1.590333e-05 -0.0244255009
3164 Q15070 OXA1L 0.2981550034 1.153250e-01 -0.0250575927
3165 P06865 HEXA -0.0187833157 9.313407e-01 0.0111440839
3166 Q4G176 ACSF3 1.1645840358 1.571268e-02 -0.0116557149
3167 O00425 IGF2BP3 -0.4670322192 8.058652e-04 -0.0088968604
3168 Q02127 DHODH 1.8919553629 5.550083e-12 0.0119945538
3169 Q14677 CLINT1 0.1495156037 2.684732e-01 0.0118688959
3170 P08651 NFIC 1.9127591142 2.248686e-15 -0.0121724593
3171 P28066 PSMA5 -0.2176952181 1.420118e-01 0.0076420581
3172 Q14249 ENDOG 0.3419305487 4.772243e-01 0.0095893912
3173 Q9UDY2 TJP2 -1.1744660791 2.003505e-08 -0.0253243845
3174 Q99755 PIP5K1A 0.0111524942 9.537761e-01 0.0418349618
3175 Q9Y2P4 SLC27A6 0.9096650750 2.543357e-01 0.0127607804
3176 P63165 SUMO1 -0.2733551581 1.024787e-01 0.0123175233
3177 Q9H019 MTFR1L 0.1761738518 6.206019e-01 -0.0092611101
3178 Q8TDY8 IGDCC4 -0.8128632371 2.440708e-03 -0.0426163562
3179 Q9NYF8 BCLAF1 0.2932623368 1.890975e-02 0.0085150296
3180 Q9HD23 MRS2 0.3101874977 4.655500e-02 0.0119060604
3181 P48723 HSPA13 0.1042271604 7.302969e-01 -0.0102901119
3182 Q99594 TEAD3 -0.6127353076 3.124291e-03 -0.0193135842
3183 Q9Y2U8 LEMD3 0.0059412212 9.832385e-01 0.0098060997
3184 O75027 ABCB7 0.9356320038 1.890166e-05 -0.0099842542
3185 Q5SSJ5 HP1BP3 0.0675528760 7.509103e-01 0.0073752285
3186 O75400 PRPF40A -0.0549315875 7.319072e-01 -0.0124379818
3187 P31327 CPS1 1.5260089265 6.817051e-04 0.0136571174
3188 Q9Y2A7 NCKAP1 0.3523055106 3.956756e-02 0.0125353448
3189 Q9UID3 VPS51 0.0771549269 6.996361e-01 0.0295843740
3190 P14543 NID1 -0.2633962284 4.247204e-01 -0.0167919221
3191 P17152 TMEM11 0.0286310894 8.567453e-01 -0.0105953273
3192 Q13620 CUL4B -0.4921538337 7.337643e-02 0.0145089750
3193 P29992 GNA11 -0.6461457364 3.650651e-07 -0.0064416056
3194 Q5T2T1 MPP7 -0.2481676820 4.607929e-01 0.0097889222
3195 P62140 PPP1CB 0.2134131014 4.178096e-01 0.0079203715
3196 Q969V3 NCLN -0.0609534742 8.747069e-01 -0.0091642882
3197 O75063 FAM20B 0.1715353466 2.151519e-01 -0.0196776515
3198 O43765 SGTA 0.2010962403 8.891681e-02 -0.0198025217
3199 Q8N2F6 ARMC10 -0.4916332128 9.634105e-04 -0.0198511112
3200 Q8WVX9 FAR1 0.6817842559 4.435381e-05 0.0060289228
3201 Q14139 UBE4A 0.0979763946 4.584974e-01 -0.0057615311
3202 P82933 MRPS9 0.5729337775 5.871366e-05 0.0054829992
3203 Q01813 PFKP 0.0705533351 8.759288e-01 0.0167370873
3204 Q9BX66 SORBS1 -0.4013435088 7.140031e-02 0.0143358680
3205 P60891 PRPS1 0.5359664952 7.300156e-02 0.0067843410
3206 P11021 HSPA5 0.2682169864 4.379946e-01 0.0063562359
3207 Q9NSV4 DIAPH3 0.7020462709 2.493912e-01 0.0171790228
3208 P02786 TFRC 1.5455329480 3.304262e-04 0.0070610326
3209 Q15075 EEA1 0.0829040645 6.871269e-01 0.0050036274
3210 P50440 GATM 0.7038263127 1.382235e-01 0.0143064229
3211 Q96ER9 CCDC51 -0.5241830027 7.299311e-03 -0.0102512056
3212 Q9H0V9 LMAN2L 0.6921431823 2.649489e-06 -0.0093153054
3213 Q96SJ8 TSPAN18 0.0674229287 8.815904e-01 -0.0156754084
3214 Q9UDR5 AASS 0.9031965755 2.943655e-03 0.0064776062
3215 Q99436 PSMB7 -0.1022043027 3.871833e-01 0.0067940073
3216 P07910 HNRNPC -0.5452201778 5.358031e-05 0.0061472861
3217 P43121 MCAM 2.0332566656 1.122956e-09 0.0072381493
3218 Q969Z3 MTARC2 0.9380548958 7.362719e-04 -0.0054001601
3219 Q9P291 ARMCX1 0.6436026123 2.930719e-03 0.0057158178
3220 Q96I51 RCC1L -0.3310989706 1.371312e-02 -0.0099153320
3221 P12270 TPR 0.4146819754 1.936013e-03 -0.0063074599
3222 P62993 GRB2 -0.0768717211 4.312790e-01 -0.0191703184
3223 O43852 CALU 0.3836205232 1.936299e-01 -0.0066212747
3224 O00186 STXBP3 -0.4161157469 1.248110e-02 -0.0047971737
3225 P61020 RAB5B -0.0792640258 5.992235e-01 0.0097273667
3226 Q9UJW0 DCTN4 0.1585282383 1.226075e-01 -0.0059093156
3227 P50213 IDH3A 0.9143527199 6.021090e-04 -0.0051954398
3228 P13861 PRKAR2A 0.1909003014 3.003278e-01 -0.0050914180
3229 Q8NDZ4 DIPK2A 0.2985381973 3.603724e-01 -0.0086632938
3230 P35659 DEK 0.6836197263 1.763743e-02 -0.0044616574
3231 P56747 CLDN6 0.4903047750 1.301154e-01 0.0187623726
3232 O95861 BPNT1 0.8153466543 1.751936e-05 -0.0054869445
3233 Q68D91 MBLAC2 -0.1752900634 4.472219e-01 -0.0095284586
3234 Q96D53 COQ8B -0.1903233352 4.352588e-01 -0.0072857034
3235 Q9GZP0 PDGFD 0.9065061387 3.524099e-02 0.0175080541
3236 Q9UBX3 SLC25A10 1.5233884781 2.215949e-10 -0.0059197351
3237 Q6Y288 B3GLCT -0.9350382810 1.592378e-03 0.0073062541
3238 Q58EX2 SDK2 1.2372282600 1.963646e-05 0.0102423104
3239 Q9P035 HACD3 0.4664993474 7.779180e-02 -0.0044522294
3240 Q92614 MYO18A 0.7032231392 5.900807e-03 -0.0028647118
3241 O75376 NCOR1 -0.6248074879 1.936455e-03 0.0074416599
3242 O43615 TIMM44 0.6372452977 2.088844e-03 0.0037622817
3243 O43169 CYB5B 0.0207338294 9.023055e-01 0.0032027964
3244 Q6UW68 TMEM205 0.7648176669 2.305697e-05 0.0046572920
3245 P35968 KDR 0.5396634797 3.298585e-01 0.0047097694
3246 Q9GZY4 COA1 0.4899337125 1.306507e-01 -0.0055021156
3247 Q8IZQ5 SELENOH 0.0080352488 9.809982e-01 0.0066248105
3248 O60841 EIF5B 0.0939207590 6.100031e-01 -0.0035220559
3249 P28288 ABCD3 0.3486283733 1.780447e-02 -0.0036256509
3250 O75417 POLQ 2.0084178247 2.456687e-08 0.0054159815
3251 Q15067 ACOX1 -0.1888053822 2.916021e-01 0.0044210791
3252 P26368 U2AF2 -0.2995128873 4.417443e-03 -0.0022281622
3253 P23919 DTYMK 1.0407036283 3.597197e-05 -0.0032968988
3254 Q155Q3 DIXDC1 -0.0216990060 9.530237e-01 0.0028108220
3255 Q13232 NME3 2.2205860983 6.412236e-09 -0.0035464856
3256 Q6FI81 CIAPIN1 0.2869803544 8.507572e-03 0.0039575492
3257 O00505 KPNA3 0.4226836097 1.074772e-03 0.0085658006
3258 Q15008 PSMD6 -0.1794564923 1.605670e-01 0.0024531736
3259 O00743 PPP6C -0.3952961380 8.692695e-06 -0.0030229107
3260 Q32P44 EML3 0.1031835408 8.208870e-01 -0.0035448747
3261 P78417 GSTO1 -0.7720264821 6.570597e-03 0.0018041193
3262 P14621 ACYP2 -2.3099234235 8.318853e-09 -0.0045005530
3263 Q9BYD1 MRPL13 -0.0843465279 7.318300e-01 0.0015316464
3264 P61586 RHOA -0.0975989751 5.854557e-01 0.0013072005
3265 Q14566 MCM6 2.5297553942 3.031080e-10 0.0021581420
3266 P10915 HAPLN1 0.7550889191 5.260410e-01 0.0050398203
3267 Q9BXS5 AP1M1 0.0372683532 8.288891e-01 -0.0015175385
3268 Q6P1M0 SLC27A4 0.2759765041 2.808763e-01 -0.0013230822
3269 Q9C0D5 TANC1 0.3162078526 1.096049e-01 0.0037181052
3270 Q15185 PTGES3 0.0428233703 8.302442e-01 0.0008048923
3271 P51153 RAB13 0.3747905233 1.379279e-02 0.0012681861
3272 P29144 TPP2 -0.6679554631 7.847579e-05 0.0012070742
3273 P09543 CNP 1.0420442423 1.296586e-05 0.0006074187
3274 Q9BZF1 OSBPL8 -0.6917398010 7.666300e-04 -0.0006529423
3275 Q92538 GBF1 0.3110954419 8.157964e-02 0.0002573516
3276 Q96N64 PWWP2A 0.0988589150 4.579309e-01 -0.0002124377
3277 Q52LJ0 FAM98B 0.2406146738 5.528765e-02 -0.0003543919
3278 P54753 EPHB3 0.6993813551 7.733194e-02 -0.0002160733
Pro_Pval sign_match delta_logFC Upper_quant Lower_quant
1 6.951913e-05 FALSE 4.0961864246 TRUE FALSE
2 2.443330e-04 TRUE 1.8245604847 FALSE FALSE
3 3.034614e-04 TRUE 1.2580368818 FALSE FALSE
4 3.918893e-04 TRUE 3.6542200096 TRUE FALSE
5 3.940743e-04 FALSE 1.3492501561 FALSE FALSE
6 8.142856e-04 FALSE 2.1115671749 TRUE FALSE
7 1.278129e-03 FALSE 3.3858026389 TRUE FALSE
8 1.572259e-03 TRUE 0.4017811005 FALSE FALSE
9 1.881965e-03 FALSE 3.0204363862 TRUE FALSE
10 1.881965e-03 FALSE 1.0569056170 FALSE FALSE
11 1.881965e-03 TRUE 0.5956266202 FALSE FALSE
12 1.881965e-03 FALSE 2.8271043027 TRUE FALSE
13 2.500644e-03 FALSE 1.0720761781 FALSE FALSE
14 2.711717e-03 FALSE 2.5718561759 TRUE FALSE
15 2.711717e-03 FALSE 1.8116489603 FALSE FALSE
16 2.717316e-03 FALSE 1.7788574655 FALSE FALSE
17 3.007123e-03 FALSE 1.0623471286 FALSE FALSE
18 3.007123e-03 FALSE 0.9322249767 FALSE FALSE
19 3.156765e-03 FALSE 2.5965406701 TRUE FALSE
20 3.156765e-03 FALSE 1.0786949217 FALSE FALSE
21 3.156765e-03 TRUE 1.0693304218 FALSE FALSE
22 3.912381e-03 FALSE 2.1865598321 TRUE FALSE
23 4.145419e-03 FALSE 1.4339970353 FALSE FALSE
24 4.358840e-03 FALSE 1.3506158167 FALSE FALSE
25 4.534280e-03 TRUE 0.4847919072 FALSE FALSE
26 4.654352e-03 FALSE 1.1456024818 FALSE FALSE
27 5.057106e-03 TRUE 1.1043775767 FALSE FALSE
28 5.057106e-03 FALSE 2.7925565575 TRUE FALSE
29 5.057106e-03 FALSE 2.9808919211 TRUE FALSE
30 5.057106e-03 FALSE 2.0825481592 TRUE FALSE
31 5.057106e-03 FALSE 1.6596221669 FALSE FALSE
32 5.472898e-03 FALSE 4.0238075319 TRUE FALSE
33 5.521477e-03 FALSE 1.8705818769 TRUE FALSE
34 5.521477e-03 TRUE 0.5830719704 FALSE FALSE
35 5.610083e-03 FALSE 4.4937132950 TRUE FALSE
36 5.610083e-03 FALSE 2.2164881676 TRUE FALSE
37 5.610083e-03 FALSE 2.0319061085 TRUE FALSE
38 6.595355e-03 FALSE 1.1499372980 FALSE FALSE
39 6.971593e-03 TRUE 0.6125415096 FALSE FALSE
40 7.360475e-03 FALSE 0.7944301004 FALSE FALSE
41 7.537546e-03 FALSE 0.7488775917 FALSE FALSE
42 7.845298e-03 TRUE 0.2881598776 FALSE FALSE
43 7.847079e-03 FALSE 1.4283475860 FALSE FALSE
44 7.847079e-03 FALSE 0.9943021551 FALSE FALSE
45 7.847079e-03 TRUE 0.5036262448 FALSE FALSE
46 8.197740e-03 FALSE 1.8966704320 TRUE FALSE
47 8.454480e-03 FALSE 1.2681497485 FALSE FALSE
48 8.635514e-03 TRUE 0.6386222300 FALSE FALSE
49 9.414723e-03 FALSE 2.0408582802 TRUE FALSE
50 1.022209e-02 TRUE 1.1039491437 FALSE FALSE
51 1.029373e-02 FALSE 1.0563313463 FALSE FALSE
52 1.029373e-02 TRUE 0.3792885928 FALSE FALSE
53 1.029373e-02 FALSE 1.2838035761 FALSE FALSE
54 1.029373e-02 FALSE 0.9504383179 FALSE FALSE
55 1.086007e-02 TRUE 1.6779040891 FALSE FALSE
56 1.086007e-02 TRUE 0.4696977730 FALSE FALSE
57 1.086007e-02 TRUE 0.5771483474 FALSE FALSE
58 1.116432e-02 FALSE 1.6367045733 FALSE FALSE
59 1.116432e-02 FALSE 0.9585857204 FALSE FALSE
60 1.116432e-02 FALSE 2.7709596064 TRUE FALSE
61 1.177343e-02 TRUE 1.7262253230 FALSE FALSE
62 1.233495e-02 FALSE 0.9300022891 FALSE FALSE
63 1.325802e-02 TRUE 0.4289246355 FALSE FALSE
64 1.325802e-02 TRUE 0.4146200045 FALSE FALSE
65 1.325802e-02 TRUE 0.4022706827 FALSE FALSE
66 1.325802e-02 FALSE 2.2560273217 TRUE FALSE
67 1.326771e-02 FALSE 0.6569515831 FALSE FALSE
68 1.326771e-02 FALSE 1.9277510943 TRUE FALSE
69 1.326771e-02 TRUE 0.6514508255 FALSE FALSE
70 1.326771e-02 TRUE 0.5465574799 FALSE FALSE
71 1.326771e-02 FALSE 1.1617534182 FALSE FALSE
72 1.333621e-02 TRUE 0.5170318875 FALSE FALSE
73 1.333621e-02 TRUE 0.2338491604 FALSE FALSE
74 1.333621e-02 FALSE 2.4411232407 TRUE FALSE
75 1.333621e-02 FALSE 0.8935294347 FALSE FALSE
76 1.333621e-02 FALSE 1.1820592459 FALSE FALSE
77 1.333621e-02 TRUE 0.6048774818 FALSE FALSE
78 1.333621e-02 FALSE 0.9381489554 FALSE FALSE
79 1.333621e-02 TRUE 0.8463901301 FALSE FALSE
80 1.349230e-02 TRUE 0.5622511342 FALSE FALSE
81 1.354980e-02 TRUE 0.4390906565 FALSE FALSE
82 1.424497e-02 TRUE 0.3394132474 FALSE FALSE
83 1.424497e-02 FALSE 0.7029390562 FALSE FALSE
84 1.429047e-02 TRUE 0.6004303130 FALSE FALSE
85 1.448893e-02 TRUE 0.2675113048 FALSE FALSE
86 1.448893e-02 FALSE 2.3755343466 TRUE FALSE
87 1.490927e-02 TRUE 0.8385777451 FALSE FALSE
88 1.511453e-02 TRUE 1.1065956371 FALSE FALSE
89 1.511453e-02 TRUE 0.8019510352 FALSE FALSE
90 1.511919e-02 TRUE 0.2027651810 FALSE FALSE
91 1.522705e-02 FALSE 1.1219898194 FALSE FALSE
92 1.540433e-02 TRUE 0.1618911967 FALSE FALSE
93 1.540433e-02 TRUE 0.3217711153 FALSE FALSE
94 1.544898e-02 TRUE 0.3992141351 FALSE FALSE
95 1.560784e-02 TRUE 0.1357322547 FALSE FALSE
96 1.592196e-02 FALSE 2.2255342515 TRUE FALSE
97 1.602160e-02 FALSE 0.9061403976 FALSE FALSE
98 1.629803e-02 TRUE 0.2398283522 FALSE FALSE
99 1.712715e-02 TRUE 0.2622166002 FALSE FALSE
100 1.754874e-02 TRUE 1.1514391487 FALSE FALSE
101 1.754874e-02 FALSE 0.7438978431 FALSE FALSE
102 1.754874e-02 FALSE 2.0312703968 TRUE FALSE
103 1.844926e-02 FALSE 0.9028499346 FALSE FALSE
104 1.847809e-02 FALSE 0.7212781213 FALSE FALSE
105 1.924691e-02 FALSE 0.6033864304 FALSE FALSE
106 1.980493e-02 TRUE 0.4225422839 FALSE FALSE
107 1.980493e-02 FALSE 1.1918443100 FALSE FALSE
108 1.999753e-02 FALSE 0.5743554200 FALSE FALSE
109 2.001937e-02 FALSE 0.9509630346 FALSE FALSE
110 2.030277e-02 TRUE 0.2081079330 FALSE FALSE
111 2.030277e-02 FALSE 1.6478580408 FALSE FALSE
112 2.030277e-02 FALSE 2.5963626496 TRUE FALSE
113 2.030277e-02 FALSE 0.8249133018 FALSE FALSE
114 2.030277e-02 FALSE 2.1140912065 TRUE FALSE
115 2.030277e-02 TRUE 1.0303577486 FALSE FALSE
116 2.030277e-02 TRUE 0.1381957548 FALSE FALSE
117 2.030277e-02 FALSE 2.4348953372 TRUE FALSE
118 2.030277e-02 FALSE 1.9898255541 TRUE FALSE
119 2.043186e-02 FALSE 1.2347437286 FALSE FALSE
120 2.062576e-02 FALSE 1.4514329576 FALSE FALSE
121 2.062576e-02 TRUE 0.2573932047 FALSE FALSE
122 2.117750e-02 TRUE 0.6145765517 FALSE FALSE
123 2.117750e-02 FALSE 1.1153085877 FALSE FALSE
124 2.117750e-02 TRUE 2.2551695346 TRUE FALSE
125 2.117750e-02 TRUE 0.6237777413 FALSE FALSE
126 2.153822e-02 FALSE 0.6590585110 FALSE FALSE
127 2.200363e-02 FALSE 1.0266017297 FALSE FALSE
128 2.245624e-02 TRUE 0.3509413277 FALSE FALSE
129 2.254563e-02 FALSE 1.7943590040 FALSE FALSE
130 2.254563e-02 TRUE 0.1794368408 FALSE FALSE
131 2.266300e-02 TRUE 0.1436771859 FALSE FALSE
132 2.302224e-02 TRUE 1.1256283650 FALSE FALSE
133 2.302224e-02 TRUE 0.1785686990 FALSE FALSE
134 2.304203e-02 FALSE 0.5313770133 FALSE FALSE
135 2.307093e-02 FALSE 0.6118603269 FALSE FALSE
136 2.307093e-02 FALSE 0.7045547385 FALSE FALSE
137 2.307093e-02 FALSE 1.2318804961 FALSE FALSE
138 2.307093e-02 FALSE 0.7351212622 FALSE FALSE
139 2.320441e-02 FALSE 0.9966578808 FALSE FALSE
140 2.320441e-02 TRUE 0.1797829579 FALSE FALSE
141 2.320441e-02 FALSE 2.4116868315 TRUE FALSE
142 2.320441e-02 TRUE 1.3993020743 FALSE FALSE
143 2.334638e-02 TRUE 0.0589645654 FALSE FALSE
144 2.352702e-02 FALSE 2.5225175350 TRUE FALSE
145 2.435103e-02 FALSE 0.6258914705 FALSE FALSE
146 2.436489e-02 FALSE 1.9398481990 TRUE FALSE
147 2.470591e-02 FALSE 8.2496045250 TRUE FALSE
148 2.542329e-02 TRUE 0.8922202907 FALSE FALSE
149 2.542329e-02 TRUE 0.0661851593 FALSE FALSE
150 2.543895e-02 FALSE 1.0013223674 FALSE FALSE
151 2.627630e-02 TRUE 0.2872363091 FALSE FALSE
152 2.627630e-02 TRUE 1.0968810670 FALSE FALSE
153 2.627630e-02 FALSE 1.7703390177 FALSE FALSE
154 2.627630e-02 FALSE 4.3386891070 TRUE FALSE
155 2.693134e-02 FALSE 0.6517052830 FALSE FALSE
156 2.700475e-02 FALSE 1.4452637773 FALSE FALSE
157 2.701559e-02 FALSE 1.7047915324 FALSE FALSE
158 2.837538e-02 TRUE 0.0510496299 FALSE FALSE
159 2.837538e-02 FALSE 1.7570147195 FALSE FALSE
160 2.843616e-02 FALSE 1.6535316380 FALSE FALSE
161 2.977678e-02 TRUE 0.1038534142 FALSE FALSE
162 2.989137e-02 FALSE 1.5881436086 FALSE FALSE
163 2.989137e-02 TRUE 0.3699534966 FALSE FALSE
164 3.000713e-02 FALSE 1.4871880284 FALSE FALSE
165 3.000713e-02 FALSE 2.9276321716 TRUE FALSE
166 3.035656e-02 FALSE 0.8554297998 FALSE FALSE
167 3.035656e-02 FALSE 1.2197640167 FALSE FALSE
168 3.035656e-02 FALSE 2.3098150655 TRUE FALSE
169 3.035656e-02 FALSE 4.8542763314 TRUE FALSE
170 3.042248e-02 FALSE 2.4982115216 TRUE FALSE
171 3.042248e-02 FALSE 1.3918582030 FALSE FALSE
172 3.042248e-02 FALSE 0.6634011466 FALSE FALSE
173 3.202089e-02 FALSE 2.4016436238 TRUE FALSE
174 3.202089e-02 TRUE 0.8285943367 FALSE FALSE
175 3.202089e-02 FALSE 1.3920527761 FALSE FALSE
176 3.202089e-02 FALSE 0.7728235367 FALSE FALSE
177 3.233857e-02 TRUE 0.9763530075 FALSE FALSE
178 3.239557e-02 TRUE 0.0388296915 FALSE TRUE
179 3.247939e-02 FALSE 0.9374410006 FALSE FALSE
180 3.342171e-02 FALSE 1.3674012805 FALSE FALSE
181 3.342171e-02 FALSE 0.7682160954 FALSE FALSE
182 3.342171e-02 FALSE 1.5672016432 FALSE FALSE
183 3.342171e-02 TRUE 0.7372646708 FALSE FALSE
184 3.342171e-02 FALSE 1.6760118176 FALSE FALSE
185 3.342171e-02 FALSE 0.6389544313 FALSE FALSE
186 3.342171e-02 FALSE 1.3599960709 FALSE FALSE
187 3.342171e-02 TRUE 0.6507742954 FALSE FALSE
188 3.342171e-02 FALSE 0.7334739513 FALSE FALSE
189 3.348689e-02 FALSE 1.3504281732 FALSE FALSE
190 3.402400e-02 FALSE 0.7709955311 FALSE FALSE
191 3.402400e-02 TRUE 0.0187742951 FALSE TRUE
192 3.463040e-02 FALSE 2.1318429280 TRUE FALSE
193 3.560446e-02 TRUE 3.2389296898 TRUE FALSE
194 3.603724e-02 TRUE 1.2990319320 FALSE FALSE
195 3.628625e-02 FALSE 1.3819921202 FALSE FALSE
196 3.679153e-02 TRUE 2.5425072877 TRUE FALSE
197 3.710355e-02 TRUE 0.7475279442 FALSE FALSE
198 3.977181e-02 FALSE 2.1182367441 TRUE FALSE
199 4.022365e-02 FALSE 0.8816213225 FALSE FALSE
200 4.048814e-02 FALSE 0.8165990022 FALSE FALSE
201 4.055141e-02 TRUE 0.3925419454 FALSE FALSE
202 4.055141e-02 TRUE 0.2608770458 FALSE FALSE
203 4.055141e-02 FALSE 0.5840926646 FALSE FALSE
204 4.055141e-02 TRUE 0.0590645196 FALSE FALSE
205 4.055141e-02 FALSE 0.9013298774 FALSE FALSE
206 4.055141e-02 TRUE 0.1742051833 FALSE FALSE
207 4.055141e-02 FALSE 1.1212854116 FALSE FALSE
208 4.117838e-02 FALSE 2.9054912584 TRUE FALSE
209 4.165285e-02 FALSE 0.9850436811 FALSE FALSE
210 4.178969e-02 FALSE 1.6117922476 FALSE FALSE
211 4.389540e-02 TRUE 0.6120554792 FALSE FALSE
212 4.393133e-02 FALSE 1.7288181814 FALSE FALSE
213 4.505482e-02 TRUE 0.0121509333 FALSE TRUE
214 4.630860e-02 FALSE 0.7234591770 FALSE FALSE
215 4.630860e-02 FALSE 0.6222823042 FALSE FALSE
216 4.870740e-02 FALSE 1.0751251707 FALSE FALSE
217 4.898881e-02 TRUE 1.5483678200 FALSE FALSE
218 5.000598e-02 TRUE 0.6140528971 FALSE FALSE
219 5.000598e-02 TRUE 0.1935052167 FALSE FALSE
220 5.000598e-02 FALSE 2.0361900263 TRUE FALSE
221 5.000598e-02 FALSE 2.5497556940 TRUE FALSE
222 5.065971e-02 FALSE 2.0401661371 TRUE FALSE
223 5.065971e-02 FALSE 1.0173352627 FALSE FALSE
224 5.067530e-02 TRUE 0.1960725269 FALSE FALSE
225 5.067530e-02 FALSE 0.8117561302 FALSE FALSE
226 5.094137e-02 FALSE 1.0882659197 FALSE FALSE
227 5.094137e-02 FALSE 0.6720459825 FALSE FALSE
228 5.094137e-02 TRUE 0.4471666255 FALSE FALSE
229 5.107644e-02 FALSE 0.5285265951 FALSE FALSE
230 5.124927e-02 FALSE 0.6095108239 FALSE FALSE
231 5.158242e-02 FALSE 1.0126594882 FALSE FALSE
232 5.206511e-02 TRUE 0.0272387756 FALSE TRUE
233 5.206511e-02 TRUE 1.0336490432 FALSE FALSE
234 5.206511e-02 TRUE 0.2795678046 FALSE FALSE
235 5.206511e-02 TRUE 0.3240474074 FALSE FALSE
236 5.206511e-02 TRUE 0.5490035332 FALSE FALSE
237 5.206511e-02 FALSE 1.3912534758 FALSE FALSE
238 5.206511e-02 FALSE 1.2008565652 FALSE FALSE
239 5.206511e-02 FALSE 1.1565439417 FALSE FALSE
240 5.206511e-02 FALSE 1.0388870784 FALSE FALSE
241 5.206511e-02 TRUE 0.4274597726 FALSE FALSE
242 5.206511e-02 FALSE 0.9601706653 FALSE FALSE
243 5.218896e-02 FALSE 1.4286661777 FALSE FALSE
244 5.218896e-02 FALSE 1.5123370274 FALSE FALSE
245 5.219070e-02 FALSE 1.4901815170 FALSE FALSE
246 5.412179e-02 TRUE 0.1952886553 FALSE FALSE
247 5.422567e-02 TRUE 0.5499380250 FALSE FALSE
248 5.422567e-02 FALSE 0.8569210111 FALSE FALSE
249 5.422567e-02 TRUE 1.1355252630 FALSE FALSE
250 5.448529e-02 TRUE 0.1544830158 FALSE FALSE
251 5.475627e-02 FALSE 1.7897613341 FALSE FALSE
252 5.516917e-02 TRUE 0.5754078185 FALSE FALSE
253 5.528313e-02 FALSE 0.6281168715 FALSE FALSE
254 5.540842e-02 FALSE 1.1411527025 FALSE FALSE
255 5.540842e-02 TRUE 0.2848291844 FALSE FALSE
256 5.570861e-02 FALSE 0.7105462668 FALSE FALSE
257 5.676170e-02 FALSE 1.3024958283 FALSE FALSE
258 5.676170e-02 FALSE 1.4784026634 FALSE FALSE
259 5.676170e-02 TRUE 1.0147349707 FALSE FALSE
260 5.676170e-02 TRUE 0.2288354200 FALSE FALSE
261 5.899884e-02 FALSE 1.9160304873 TRUE FALSE
262 5.917298e-02 FALSE 1.3337056619 FALSE FALSE
263 5.917298e-02 FALSE 3.6088893084 TRUE FALSE
264 5.917298e-02 FALSE 1.2936864318 FALSE FALSE
265 5.939682e-02 TRUE 0.4193074680 FALSE FALSE
266 5.954697e-02 FALSE 1.4702078995 FALSE FALSE
267 6.001444e-02 TRUE 0.1002639133 FALSE FALSE
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1897 5.656654e-01 FALSE 1.0403840877 FALSE FALSE
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1899 5.665388e-01 TRUE 0.0768561887 FALSE FALSE
1900 5.673264e-01 TRUE 0.6943895023 FALSE FALSE
1901 5.673264e-01 FALSE 2.3102415496 TRUE FALSE
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1908 5.675903e-01 TRUE 0.0894864195 FALSE FALSE
1909 5.675903e-01 FALSE 0.3645943642 FALSE FALSE
1910 5.675903e-01 TRUE 0.2924651789 FALSE FALSE
1911 5.675903e-01 TRUE 0.2231446650 FALSE FALSE
1912 5.684372e-01 TRUE 0.2821327450 FALSE FALSE
1913 5.684372e-01 FALSE 0.2906401377 FALSE FALSE
1914 5.689242e-01 FALSE 1.8068338361 FALSE FALSE
1915 5.689242e-01 FALSE 0.4302737214 FALSE FALSE
1916 5.694268e-01 TRUE 0.3079213375 FALSE FALSE
1917 5.702876e-01 TRUE 0.2045939152 FALSE FALSE
1918 5.710872e-01 FALSE 0.6028993308 FALSE FALSE
1919 5.710872e-01 TRUE 0.1453015106 FALSE FALSE
1920 5.710872e-01 FALSE 0.9806752829 FALSE FALSE
1921 5.710872e-01 TRUE 0.6465710210 FALSE FALSE
1922 5.712245e-01 FALSE 0.2490450462 FALSE FALSE
1923 5.712330e-01 FALSE 0.6994388092 FALSE FALSE
1924 5.712330e-01 TRUE 0.5449100071 FALSE FALSE
1925 5.712330e-01 TRUE 0.4762100047 FALSE FALSE
1926 5.712330e-01 TRUE 0.0460088046 FALSE TRUE
1927 5.712330e-01 TRUE 0.0200811232 FALSE TRUE
1928 5.712330e-01 TRUE 0.2574335916 FALSE FALSE
1929 5.712330e-01 FALSE 1.3394764515 FALSE FALSE
1930 5.712330e-01 TRUE 0.3596022844 FALSE FALSE
1931 5.712330e-01 TRUE 0.1360319849 FALSE FALSE
1932 5.712330e-01 TRUE 0.0631615071 FALSE FALSE
1933 5.714770e-01 FALSE 0.2348559328 FALSE FALSE
1934 5.718801e-01 TRUE 0.2310383371 FALSE FALSE
1935 5.718801e-01 TRUE 1.9881419960 TRUE FALSE
1936 5.718801e-01 TRUE 0.2842764664 FALSE FALSE
1937 5.718801e-01 FALSE 1.0246518906 FALSE FALSE
1938 5.718801e-01 FALSE 0.3683755809 FALSE FALSE
1939 5.718801e-01 FALSE 0.9978271828 FALSE FALSE
1940 5.719697e-01 TRUE 0.2108568091 FALSE FALSE
1941 5.719697e-01 TRUE 0.8463743632 FALSE FALSE
1942 5.719697e-01 FALSE 0.6219411267 FALSE FALSE
1943 5.719697e-01 FALSE 0.1645802952 FALSE FALSE
1944 5.735147e-01 TRUE 0.4270642117 FALSE FALSE
1945 5.735147e-01 TRUE 0.1144005331 FALSE FALSE
1946 5.747606e-01 FALSE 0.2305187521 FALSE FALSE
1947 5.763274e-01 FALSE 1.4193567490 FALSE FALSE
1948 5.764383e-01 FALSE 1.3811604095 FALSE FALSE
1949 5.773523e-01 TRUE 0.1374358896 FALSE FALSE
1950 5.773523e-01 FALSE 0.5506244854 FALSE FALSE
1951 5.773523e-01 FALSE 0.1536404179 FALSE FALSE
1952 5.773523e-01 TRUE 0.2776089996 FALSE FALSE
1953 5.787569e-01 FALSE 0.2795711342 FALSE FALSE
1954 5.795229e-01 TRUE 0.5090876789 FALSE FALSE
1955 5.809205e-01 FALSE 0.1360420905 FALSE FALSE
1956 5.812177e-01 FALSE 0.2774982542 FALSE FALSE
1957 5.813925e-01 TRUE 0.0678512420 FALSE FALSE
1958 5.813925e-01 TRUE 0.4580536540 FALSE FALSE
1959 5.815482e-01 FALSE 0.8101521000 FALSE FALSE
1960 5.818973e-01 FALSE 0.1904407039 FALSE FALSE
1961 5.818973e-01 FALSE 1.5960478957 FALSE FALSE
1962 5.818973e-01 TRUE 0.0832611825 FALSE FALSE
1963 5.835379e-01 TRUE 0.0064784432 FALSE TRUE
1964 5.838129e-01 TRUE 0.0679374414 FALSE FALSE
1965 5.863497e-01 TRUE 1.4766782916 FALSE FALSE
1966 5.883124e-01 TRUE 0.1523323531 FALSE FALSE
1967 5.888986e-01 TRUE 0.2471974515 FALSE FALSE
1968 5.891983e-01 TRUE 0.4273256425 FALSE FALSE
1969 5.892028e-01 FALSE 0.9965212220 FALSE FALSE
1970 5.894094e-01 TRUE 1.1729823564 FALSE FALSE
1971 5.897020e-01 TRUE 0.5266558157 FALSE FALSE
1972 5.897020e-01 TRUE 0.1663188634 FALSE FALSE
1973 5.897982e-01 TRUE 0.3573235729 FALSE FALSE
1974 5.897982e-01 FALSE 0.3087994876 FALSE FALSE
1975 5.908133e-01 FALSE 0.4230364616 FALSE FALSE
1976 5.912307e-01 FALSE 1.6346349916 FALSE FALSE
1977 5.914293e-01 FALSE 0.6653394833 FALSE FALSE
1978 5.914293e-01 TRUE 0.9066320567 FALSE FALSE
1979 5.914293e-01 TRUE 0.7348820381 FALSE FALSE
1980 5.933894e-01 TRUE 0.4838656745 FALSE FALSE
1981 5.935323e-01 FALSE 0.8550985833 FALSE FALSE
1982 5.936906e-01 TRUE 0.4356792180 FALSE FALSE
1983 5.940249e-01 FALSE 0.5716954271 FALSE FALSE
1984 5.940249e-01 TRUE 0.0717965844 FALSE FALSE
1985 5.940717e-01 FALSE 1.3049073482 FALSE FALSE
1986 5.943942e-01 TRUE 0.0628017409 FALSE FALSE
1987 5.961792e-01 TRUE 0.0477508513 FALSE FALSE
1988 5.963798e-01 TRUE 0.2204097844 FALSE FALSE
1989 5.963798e-01 TRUE 1.5266574167 FALSE FALSE
1990 5.963798e-01 FALSE 0.2030270823 FALSE FALSE
1991 5.975355e-01 TRUE 0.0439933713 FALSE TRUE
1992 5.982233e-01 TRUE 0.1699492548 FALSE FALSE
1993 5.982233e-01 FALSE 0.3838737236 FALSE FALSE
1994 5.983942e-01 FALSE 2.5762019882 TRUE FALSE
1995 5.983942e-01 FALSE 0.9604296749 FALSE FALSE
1996 5.986018e-01 FALSE 0.7541305100 FALSE FALSE
1997 5.986018e-01 TRUE 0.0692050538 FALSE FALSE
1998 5.986018e-01 FALSE 0.3780686017 FALSE FALSE
1999 5.997232e-01 FALSE 0.3174192330 FALSE FALSE
2000 5.997232e-01 TRUE 0.1231529782 FALSE FALSE
2001 5.997232e-01 TRUE 0.1508992661 FALSE FALSE
2002 6.010098e-01 FALSE 1.2611720377 FALSE FALSE
2003 6.029413e-01 TRUE 0.2351870195 FALSE FALSE
2004 6.032727e-01 FALSE 0.2923716733 FALSE FALSE
2005 6.033354e-01 FALSE 0.6605127791 FALSE FALSE
2006 6.033354e-01 TRUE 0.1652059401 FALSE FALSE
2007 6.033354e-01 FALSE 1.0683899416 FALSE FALSE
2008 6.033354e-01 TRUE 0.8063425643 FALSE FALSE
2009 6.038950e-01 FALSE 0.2486655898 FALSE FALSE
2010 6.038950e-01 TRUE 0.2311438715 FALSE FALSE
2011 6.038950e-01 FALSE 0.7839049182 FALSE FALSE
2012 6.042933e-01 FALSE 0.2522323291 FALSE FALSE
2013 6.043505e-01 FALSE 0.5123281772 FALSE FALSE
2014 6.045983e-01 FALSE 0.7116042644 FALSE FALSE
2015 6.047004e-01 TRUE 0.0327845820 FALSE TRUE
2016 6.049673e-01 TRUE 1.5794290043 FALSE FALSE
2017 6.049673e-01 FALSE 0.4347481095 FALSE FALSE
2018 6.049673e-01 TRUE 0.2484052721 FALSE FALSE
2019 6.049673e-01 TRUE 0.6499834422 FALSE FALSE
2020 6.056234e-01 FALSE 0.8063661561 FALSE FALSE
2021 6.056234e-01 FALSE 0.6183100604 FALSE FALSE
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3033 9.280449e-01 FALSE 0.1301679698 FALSE FALSE
3034 9.280534e-01 FALSE 0.6700846663 FALSE FALSE
3035 9.289318e-01 FALSE 0.7273108628 FALSE FALSE
3036 9.289318e-01 TRUE 0.1078566676 FALSE FALSE
3037 9.294717e-01 FALSE 0.4826262821 FALSE FALSE
3038 9.313276e-01 TRUE 0.8678730473 FALSE FALSE
3039 9.313276e-01 TRUE 0.1719498222 FALSE FALSE
3040 9.318851e-01 FALSE 0.7592809986 FALSE FALSE
3041 9.328509e-01 FALSE 0.8199064909 FALSE FALSE
3042 9.328509e-01 FALSE 0.2135766067 FALSE FALSE
3043 9.328509e-01 TRUE 0.7422246167 FALSE FALSE
3044 9.333338e-01 TRUE 0.3077849207 FALSE FALSE
3045 9.333833e-01 FALSE 0.5854517320 FALSE FALSE
3046 9.335755e-01 FALSE 1.5487391139 FALSE FALSE
3047 9.335755e-01 FALSE 0.5222980630 FALSE FALSE
3048 9.342376e-01 TRUE 0.0936558553 FALSE FALSE
3049 9.342376e-01 TRUE 0.1693912507 FALSE FALSE
3050 9.342376e-01 FALSE 1.3755271082 FALSE FALSE
3051 9.350745e-01 FALSE 0.5491415762 FALSE FALSE
3052 9.350745e-01 TRUE 0.2494202684 FALSE FALSE
3053 9.350745e-01 TRUE 0.2492895774 FALSE FALSE
3054 9.350745e-01 TRUE 0.4893569129 FALSE FALSE
3055 9.354669e-01 TRUE 0.5650180100 FALSE FALSE
3056 9.356455e-01 TRUE 0.0400540839 FALSE TRUE
3057 9.364553e-01 TRUE 1.2910564640 FALSE FALSE
3058 9.364553e-01 FALSE 0.7067899167 FALSE FALSE
3059 9.373931e-01 FALSE 0.3727393910 FALSE FALSE
3060 9.382427e-01 TRUE 0.2695445800 FALSE FALSE
3061 9.385455e-01 FALSE 0.2561331800 FALSE FALSE
3062 9.385455e-01 TRUE 0.0584821865 FALSE FALSE
3063 9.385455e-01 TRUE 0.8797420357 FALSE FALSE
3064 9.385455e-01 TRUE 0.3923139192 FALSE FALSE
3065 9.385455e-01 FALSE 0.3838340022 FALSE FALSE
3066 9.390736e-01 TRUE 0.8163660427 FALSE FALSE
3067 9.390736e-01 FALSE 0.8311486734 FALSE FALSE
3068 9.390736e-01 FALSE 1.5681957378 FALSE FALSE
3069 9.391245e-01 FALSE 0.3487739300 FALSE FALSE
3070 9.404331e-01 FALSE 0.3108079165 FALSE FALSE
3071 9.409302e-01 FALSE 0.6925927138 FALSE FALSE
3072 9.413736e-01 TRUE 0.7448465275 FALSE FALSE
3073 9.421754e-01 TRUE 0.2126160011 FALSE FALSE
3074 9.421754e-01 TRUE 0.1834838972 FALSE FALSE
3075 9.435194e-01 FALSE 1.0449087844 FALSE FALSE
3076 9.439150e-01 TRUE 0.7494238644 FALSE FALSE
3077 9.439150e-01 FALSE 0.1846156705 FALSE FALSE
3078 9.439150e-01 FALSE 0.8775607081 FALSE FALSE
3079 9.439150e-01 FALSE 0.5326196804 FALSE FALSE
3080 9.439150e-01 FALSE 1.2899092691 FALSE FALSE
3081 9.440395e-01 TRUE 0.4291898986 FALSE FALSE
3082 9.440395e-01 FALSE 0.2066727875 FALSE FALSE
3083 9.440395e-01 FALSE 0.3817218257 FALSE FALSE
3084 9.440395e-01 TRUE 0.3599988466 FALSE FALSE
3085 9.443995e-01 FALSE 0.1304807899 FALSE FALSE
3086 9.452443e-01 FALSE 0.0953287176 FALSE FALSE
3087 9.454735e-01 TRUE 0.1904708193 FALSE FALSE
3088 9.455285e-01 FALSE 0.1120669463 FALSE FALSE
3089 9.464674e-01 FALSE 1.6471988858 FALSE FALSE
3090 9.465708e-01 TRUE 0.4904310228 FALSE FALSE
3091 9.467461e-01 TRUE 0.0275961821 FALSE TRUE
3092 9.467461e-01 FALSE 0.3551554790 FALSE FALSE
3093 9.467461e-01 FALSE 0.2309748427 FALSE FALSE
3094 9.467461e-01 TRUE 2.7313702728 TRUE FALSE
3095 9.468161e-01 FALSE 0.5374157338 FALSE FALSE
3096 9.490693e-01 FALSE 0.6287767551 FALSE FALSE
3097 9.493948e-01 TRUE 0.9201139025 FALSE FALSE
3098 9.506632e-01 TRUE 0.1892352105 FALSE FALSE
3099 9.508487e-01 FALSE 0.3098662482 FALSE FALSE
3100 9.509313e-01 FALSE 0.2329670308 FALSE FALSE
3101 9.509619e-01 FALSE 0.3732973217 FALSE FALSE
3102 9.509619e-01 TRUE 0.6972953959 FALSE FALSE
3103 9.509619e-01 FALSE 0.1921851559 FALSE FALSE
3104 9.511539e-01 FALSE 0.1249460938 FALSE FALSE
3105 9.524523e-01 TRUE 0.0031894178 FALSE TRUE
3106 9.530465e-01 FALSE 0.5417545747 FALSE FALSE
3107 9.532769e-01 FALSE 2.7439950525 TRUE FALSE
3108 9.532769e-01 FALSE 2.9721510243 TRUE FALSE
3109 9.532769e-01 FALSE 2.3054002259 TRUE FALSE
3110 9.532769e-01 FALSE 2.0800856256 TRUE FALSE
3111 9.532769e-01 TRUE 0.1193551818 FALSE FALSE
3112 9.532769e-01 TRUE 0.1613225945 FALSE FALSE
3113 9.542532e-01 TRUE 0.0709216923 FALSE FALSE
3114 9.573678e-01 FALSE 0.3098563180 FALSE FALSE
3115 9.573678e-01 FALSE 0.3842156385 FALSE FALSE
3116 9.573678e-01 FALSE 0.5387511704 FALSE FALSE
3117 9.573678e-01 FALSE 0.1899138854 FALSE FALSE
3118 9.576748e-01 TRUE 0.0330923510 FALSE TRUE
3119 9.578815e-01 FALSE 1.4097274683 FALSE FALSE
3120 9.585062e-01 TRUE 0.0321902526 FALSE TRUE
3121 9.585062e-01 TRUE 0.2916722615 FALSE FALSE
3122 9.588010e-01 TRUE 0.4588112406 FALSE FALSE
3123 9.590088e-01 TRUE 0.4143529317 FALSE FALSE
3124 9.592422e-01 TRUE 0.5014504864 FALSE FALSE
3125 9.592422e-01 TRUE 0.0659842695 FALSE FALSE
3126 9.601543e-01 TRUE 0.4962259921 FALSE FALSE
3127 9.603356e-01 FALSE 0.1619363050 FALSE FALSE
3128 9.603356e-01 FALSE 0.1906868302 FALSE FALSE
3129 9.603356e-01 TRUE 1.5930424955 FALSE FALSE
3130 9.603356e-01 FALSE 0.3261287239 FALSE FALSE
3131 9.603356e-01 FALSE 0.0332184436 FALSE TRUE
3132 9.603356e-01 TRUE 0.0496800292 FALSE FALSE
3133 9.603356e-01 TRUE 0.2250988293 FALSE FALSE
3134 9.603700e-01 TRUE 0.3548986385 FALSE FALSE
3135 9.611400e-01 TRUE 0.4307512343 FALSE FALSE
3136 9.620671e-01 FALSE 0.3480977704 FALSE FALSE
3137 9.623151e-01 FALSE 0.5169305955 FALSE FALSE
3138 9.627406e-01 TRUE 0.3819959141 FALSE FALSE
3139 9.633472e-01 FALSE 0.4673964209 FALSE FALSE
3140 9.633472e-01 FALSE 0.3428450553 FALSE FALSE
3141 9.633472e-01 FALSE 0.2760209348 FALSE FALSE
3142 9.633472e-01 FALSE 0.2616941636 FALSE FALSE
3143 9.636073e-01 TRUE 0.3684968572 FALSE FALSE
3144 9.636073e-01 TRUE 0.0869530796 FALSE FALSE
3145 9.636073e-01 FALSE 0.4540771643 FALSE FALSE
3146 9.636073e-01 TRUE 0.6149016696 FALSE FALSE
3147 9.636073e-01 TRUE 0.9340593349 FALSE FALSE
3148 9.636073e-01 TRUE 0.7259667598 FALSE FALSE
3149 9.636073e-01 TRUE 0.1053487970 FALSE FALSE
3150 9.636073e-01 FALSE 1.3215030852 FALSE FALSE
3151 9.636750e-01 TRUE 0.9700007508 FALSE FALSE
3152 9.636750e-01 TRUE 0.5658304557 FALSE FALSE
3153 9.636750e-01 TRUE 1.1986858614 FALSE FALSE
3154 9.639401e-01 TRUE 0.0918763402 FALSE FALSE
3155 9.642394e-01 TRUE 0.0259534220 FALSE TRUE
3156 9.642394e-01 FALSE 0.0946984908 FALSE FALSE
3157 9.642394e-01 FALSE 0.6897634212 FALSE FALSE
3158 9.642394e-01 FALSE 1.1376147436 FALSE FALSE
3159 9.642394e-01 TRUE 0.1231332393 FALSE FALSE
3160 9.642394e-01 FALSE 1.2886381752 FALSE FALSE
3161 9.642394e-01 TRUE 1.0626820288 FALSE FALSE
3162 9.642394e-01 FALSE 0.1562504288 FALSE FALSE
3163 9.642394e-01 TRUE 0.6178900715 FALSE FALSE
3164 9.654389e-01 FALSE 0.3232125960 FALSE FALSE
3165 9.654389e-01 FALSE 0.0299273996 FALSE TRUE
3166 9.667488e-01 FALSE 1.1762397507 FALSE FALSE
3167 9.667488e-01 TRUE 0.4581353588 FALSE FALSE
3168 9.667488e-01 TRUE 1.8799608091 TRUE FALSE
3169 9.667488e-01 TRUE 0.1376467078 FALSE FALSE
3170 9.667488e-01 FALSE 1.9249315735 TRUE FALSE
3171 9.667488e-01 FALSE 0.2253372762 FALSE FALSE
3172 9.667488e-01 TRUE 0.3323411576 FALSE FALSE
3173 9.667488e-01 TRUE 1.1491416946 FALSE FALSE
3174 9.667488e-01 TRUE 0.0306824676 FALSE TRUE
3175 9.673031e-01 TRUE 0.8969042946 FALSE FALSE
3176 9.678086e-01 FALSE 0.2856726814 FALSE FALSE
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3180 9.679082e-01 TRUE 0.2982814373 FALSE FALSE
3181 9.680796e-01 FALSE 0.1145172723 FALSE FALSE
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3183 9.682065e-01 TRUE 0.0038648785 FALSE TRUE
3184 9.691118e-01 FALSE 0.9456162580 FALSE FALSE
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3187 9.691118e-01 TRUE 1.5123518091 FALSE FALSE
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3190 9.691118e-01 TRUE 0.2466043063 FALSE FALSE
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3198 9.721262e-01 FALSE 0.2208987620 FALSE FALSE
3199 9.735650e-01 TRUE 0.4717821017 FALSE FALSE
3200 9.759324e-01 TRUE 0.6757553331 FALSE FALSE
3201 9.772588e-01 FALSE 0.1037379257 FALSE FALSE
3202 9.781625e-01 TRUE 0.5674507783 FALSE FALSE
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3209 9.790569e-01 TRUE 0.0779004371 FALSE FALSE
3210 9.791069e-01 TRUE 0.6895198897 FALSE FALSE
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3212 9.793194e-01 FALSE 0.7014584876 FALSE FALSE
3213 9.800853e-01 FALSE 0.0830983370 FALSE FALSE
3214 9.812624e-01 TRUE 0.8967189692 FALSE FALSE
3215 9.812624e-01 FALSE 0.1089983100 FALSE FALSE
3216 9.812624e-01 FALSE 0.5513674640 FALSE FALSE
3217 9.812624e-01 TRUE 2.0260185163 TRUE FALSE
3218 9.812624e-01 FALSE 0.9434550559 FALSE FALSE
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3220 9.813716e-01 TRUE 0.3211836386 FALSE FALSE
3221 9.814281e-01 FALSE 0.4209894352 FALSE FALSE
3222 9.814281e-01 TRUE 0.0577014027 FALSE FALSE
3223 9.814281e-01 FALSE 0.3902417979 FALSE FALSE
3224 9.833495e-01 TRUE 0.4113185731 FALSE FALSE
3225 9.835213e-01 FALSE 0.0889913924 FALSE FALSE
3226 9.846886e-01 FALSE 0.1644375539 FALSE FALSE
3227 9.848765e-01 FALSE 0.9195481597 FALSE FALSE
3228 9.850378e-01 FALSE 0.1959917194 FALSE FALSE
3229 9.850378e-01 FALSE 0.3072014911 FALSE FALSE
3230 9.850378e-01 FALSE 0.6880813836 FALSE FALSE
3231 9.850378e-01 TRUE 0.4715424025 FALSE FALSE
3232 9.850378e-01 FALSE 0.8208335989 FALSE FALSE
3233 9.858407e-01 TRUE 0.1657616048 FALSE FALSE
3234 9.858407e-01 TRUE 0.1830376318 FALSE FALSE
3235 9.858407e-01 TRUE 0.8889980846 FALSE FALSE
3236 9.859879e-01 FALSE 1.5293082131 FALSE FALSE
3237 9.860329e-01 FALSE 0.9423445351 FALSE FALSE
3238 9.860329e-01 TRUE 1.2269859497 FALSE FALSE
3239 9.860329e-01 FALSE 0.4709515767 FALSE FALSE
3240 9.861940e-01 FALSE 0.7060878510 FALSE FALSE
3241 9.864562e-01 FALSE 0.6322491478 FALSE FALSE
3242 9.867703e-01 TRUE 0.6334830160 FALSE FALSE
3243 9.867703e-01 TRUE 0.0175310330 FALSE TRUE
3244 9.871844e-01 TRUE 0.7601603750 FALSE FALSE
3245 9.871844e-01 TRUE 0.5349537103 FALSE FALSE
3246 9.872469e-01 FALSE 0.4954358280 FALSE FALSE
3247 9.874605e-01 TRUE 0.0014104384 FALSE TRUE
3248 9.874605e-01 FALSE 0.0974428150 FALSE FALSE
3249 9.874895e-01 FALSE 0.3522540242 FALSE FALSE
3250 9.888887e-01 TRUE 2.0030018432 TRUE FALSE
3251 9.892688e-01 FALSE 0.1932264613 FALSE FALSE
3252 9.897040e-01 TRUE 0.2972847251 FALSE FALSE
3253 9.897040e-01 FALSE 1.0440005271 FALSE FALSE
3254 9.897040e-01 FALSE 0.0245098280 FALSE TRUE
3255 9.897040e-01 FALSE 2.2241325840 TRUE FALSE
3256 9.897296e-01 TRUE 0.2830228052 FALSE FALSE
3257 9.910911e-01 TRUE 0.4141178091 FALSE FALSE
3258 9.913235e-01 FALSE 0.1819096659 FALSE FALSE
3259 9.914644e-01 TRUE 0.3922732274 FALSE FALSE
3260 9.930230e-01 FALSE 0.1067284155 FALSE FALSE
3261 9.932506e-01 FALSE 0.7738306014 FALSE FALSE
3262 9.933680e-01 TRUE 2.3054228706 TRUE FALSE
3263 9.934303e-01 FALSE 0.0858781743 FALSE FALSE
3264 9.936857e-01 FALSE 0.0989061756 FALSE FALSE
3265 9.937611e-01 TRUE 2.5275972523 TRUE FALSE
3266 9.940434e-01 TRUE 0.7500490988 FALSE FALSE
3267 9.955052e-01 FALSE 0.0387858918 FALSE TRUE
3268 9.955410e-01 FALSE 0.2772995863 FALSE FALSE
3269 9.955410e-01 TRUE 0.3124897474 FALSE FALSE
3270 9.955435e-01 TRUE 0.0420184780 FALSE TRUE
3271 9.955435e-01 TRUE 0.3735223372 FALSE FALSE
3272 9.958267e-01 FALSE 0.6691625373 FALSE FALSE
3273 9.981702e-01 TRUE 1.0414368237 FALSE FALSE
3274 9.988664e-01 TRUE 0.6910868588 FALSE FALSE
3275 9.991413e-01 TRUE 0.3108380903 FALSE FALSE
3276 9.991413e-01 FALSE 0.0990713527 FALSE FALSE
3277 9.991413e-01 FALSE 0.2409690657 FALSE FALSE
3278 9.991413e-01 FALSE 0.6995974284 FALSE FALSEwrite_csv(x = New_RNA_PRO_DF, "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Data_Frames/Important_DF_Final/Pro_RNA_Sign_Divergent.csv")
New_RNA_PRO_DF %>% head() uniprotswissprot hgnc_symbol RNA_LogFC RNA_Pval Pro_LogFC Pro_Pval
1 Q15327 ANKRD1 0.542369649 0.3495016 -3.553817 6.951913e-05
2 O76021 RSL1D1 -0.316532413 0.0903693 -2.141093 2.443330e-04
3 Q96LW7 CARD19 -0.376258841 0.1269744 -1.634296 3.034614e-04
4 Q969Q1 TRIM63 -0.688160365 0.1389441 -4.342380 3.918893e-04
5 P19388 POLR2E 0.183353536 0.1788005 -1.165897 3.940743e-04
6 O43159 RRP8 0.001877949 0.9922191 -2.109689 8.142856e-04
sign_match delta_logFC Upper_quant Lower_quant
1 FALSE 4.096186 TRUE FALSE
2 TRUE 1.824560 FALSE FALSE
3 TRUE 1.258037 FALSE FALSE
4 TRUE 3.654220 TRUE FALSE
5 FALSE 1.349250 FALSE FALSE
6 FALSE 2.111567 TRUE FALSE# High Divergent Gene-Proteins HF
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Upper_quant == TRUE, ]$hgnc_symbol
Non_DE_Divergent [1] "ANKRD1" "TRIM63" "RRP8" "VASN" "QKI" "MYBBP1A"
[7] "TPBG" "NUCB1" "H1-10" "RCC2" "SLC30A1" "GNL3"
[13] "RPL22L1" "BAD" "FADS2" "FAM120A" "SMC3" "FKBP5"
[19] "LSM2" "BAIAP2" "KDSR" "USP28" "EXOSC10" "ATP6AP2"
[25] "ACLY" "TUBB3" "THBS1" "GJA1" "S1PR1" "CD46"
[31] "PES1" "DPF3" "TRIM54" "POLR1E" "VCAM1" "LMOD2"
[37] "LGR4" "MBNL1" "LRRC10" "CAND2" "SLC1A5" "TKT"
[43] "CCNA1" "RPL36AL" "PAK4" "LRRN4" "MCM8" "FUCA1"
[49] "STIM1" "WDR43" "KLHL31" "LDLR" "TNNT1" "MAGOHB"
[55] "CHCHD6" "TUBB" "MRPL17" "SPHKAP" "MRPL15" "SLC39A14"
[61] "KRT10" "ATP8A2" "PTPRD" "EXOSC8" "TUBA4A" "RDH10"
[67] "NCEH1" "RBFOX1" "TNNI3" "EPHX1" "KDM3B" "TAP1"
[73] "NLGN1" "NPM3" "TP53I3" "EIF2B1" "FHOD3" "PPP1R12B"
[79] "SLC25A15" "TMEM177" "YES1" "LGALS3" "RAB33B" "WHRN"
[85] "FDXR" "TENT5A" "DDAH1" "TCAP" "MYH13" "CASP3"
[91] "NAV1" "MCM5" "TPM4" "TOP2A" "GPC6" "SIDT2"
[97] "BLVRB" "IKBIP" "TNS1" "ZWINT" "ICAM1" "CYP2J2"
[103] "PCNA" "PTPRZ1" "XIRP2" "THEM6" "SCN5A" "CCDC60"
[109] "ARHGAP10" "EPPK1" "ENDOD1" "GPRIN3" "EPSTI1" "MYH7"
[115] "CISD3" "MCM3" "STAT1" "LDB3" "GPX1" "TXNRD1"
[121] "DDAH2" "RAB9B" "SLC16A7" "ITGB1BP2" "BDH1" "LMOD1"
[127] "MYH6" "PLXNA4" "SLC25A12" "FITM1" "DTL" "AQP1"
[133] "ANXA4" "OBSCN" "ATP1A3" "FSIP2" "KRT19" "SLC9A1"
[139] "NRAP" "EI24" "GPX8" "SLC8A1" "MCM2" "MKI67"
[145] "DPF1" "SYNPO2" "DUOX2" "ARMCX2" "CSPG4" "CACNB1"
[151] "CEP170B" "SLC25A40" "MIS18BP1" "H4C8" "H4C5" "H4C15"
[157] "H4C14" "DHODH" "NFIC" "MCAM" "POLQ" "NME3"
[163] "ACYP2" "MCM6" GWAS_Exp <- intersect(Expressed_protein, HF_GWAS_Expressed)
GWAS_Exp[1] "GTF2I" "SPEN" "CACNB2" "HSD17B12" "BAG3" "YWHAE" "SYNPO2L"
[8] "ALDH2" "NPC1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 164# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 9# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3105# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 6.6505e-26, df = 1, p-value = 1# Low Divergent Gene-Proteins HF
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Lower_quant == TRUE, ]$hgnc_symbol
Non_DE_Divergent [1] "RPS19" "ECSIT" "TMEM192" "BCAM" "CACNA1D" "VMA21"
[7] "CAPNS1" "MAP1A" "EIF3I" "ERLIN1" "CAPZB" "MAGI2"
[13] "NAPG" "CSRP3" "TBRG4" "RSF1" "NECTIN2" "SAR1A"
[19] "PDHB" "GRSF1" "NPTN" "CDS2" "EIF5A" "EXOSC4"
[25] "KIRREL1" "DCTN1" "APEH" "PDHA1" "NIT2" "TFG"
[31] "PMPCB" "NLN" "RMND1" "SEPTIN7" "DYNLL1" "FH"
[37] "RPA2" "RHOT2" "RPL6" "XXYLT1" "NDUFA7" "EIF3D"
[43] "COLGALT2" "ASAH1" "ANXA7" "ETFDH" "DECR1" "CD81"
[49] "EXTL3" "PDXP" "NSUN2" "MARCHF5" "CPVL" "TXNRD2"
[55] "TMED10" "FLOT2" "CPSF7" "SIN3A" "TOR1AIP2" "ELOB"
[61] "NDUFA13" "LNPEP" "GLB1" "ME2" "XPO1" "GLO1"
[67] "RINT1" "SLC25A22" "PDPR" "ANO6" "PPIC" "EHD4"
[73] "HSP90AB1" "SLC39A6" "NOMO1" "GATB" "MTX1" "SLC25A13"
[79] "VDAC1" "KPNA4" "DDX23" "TRMT6" "DSP" "STXBP2"
[85] "ANK3" "MTIF2" "GRPEL1" "DBT" "CCT2" "CLYBL"
[91] "IST1" "SLC15A4" "OGDH" "CUL1" "RDH14" "ALDH5A1"
[97] "LARS2" "U2AF1" "ABLIM1" "AGPS" "VKORC1L1" "LAMTOR1"
[103] "ZNF777" "NDUFB3" "PTTG1IP" "MRPS11" "DNAJA2" "IPO5"
[109] "GSTM3" "PARL" "ACAD11" "EMC8" "SEC11A" "SNRNP70"
[115] "TAF15" "PPP2CA" "POMK" "NDUFAF1" "IARS2" "TIMM22"
[121] "PELP1" "PTGR3" "SEC24B" "FUNDC2" "ABCC4" "PURA"
[127] "AP3B1" "VCP" "SCO1" "MGAT2" "DOCK7" "LUC7L2"
[133] "PROS1" "CAST" "PPP2R5D" "ODR4" "RCN1" "HCCS"
[139] "CHID1" "RAD23B" "CYP20A1" "PDIA5" "PRPF4" "PRAF2"
[145] "DGUOK" "COX20" "U2SURP" "WDR20" "SCO2" "ECHS1"
[151] "GLRX3" "DCAF8" "PSMC2" "PYROXD2" "HEXA" "PIP5K1A"
[157] "LEMD3" "PRPF40A" "TMEM11" "CYB5B" "SELENOH" "DIXDC1"
[163] "AP1M1" "PTGES3" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 164# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 9# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3105# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 6.6505e-26, df = 1, p-value = 1# High Divergent Gene-Proteins CAD Upper .95, 0.9
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Upper_quant == TRUE, ]$hgnc_symbol
Non_DE_Divergent [1] "ANKRD1" "TRIM63" "RRP8" "VASN" "QKI" "MYBBP1A"
[7] "TPBG" "NUCB1" "H1-10" "RCC2" "SLC30A1" "GNL3"
[13] "RPL22L1" "BAD" "FADS2" "FAM120A" "SMC3" "FKBP5"
[19] "LSM2" "BAIAP2" "KDSR" "USP28" "EXOSC10" "ATP6AP2"
[25] "ACLY" "TUBB3" "THBS1" "GJA1" "S1PR1" "CD46"
[31] "PES1" "DPF3" "TRIM54" "POLR1E" "VCAM1" "LMOD2"
[37] "LGR4" "MBNL1" "LRRC10" "CAND2" "SLC1A5" "TKT"
[43] "CCNA1" "RPL36AL" "PAK4" "LRRN4" "MCM8" "FUCA1"
[49] "STIM1" "WDR43" "KLHL31" "LDLR" "TNNT1" "MAGOHB"
[55] "CHCHD6" "TUBB" "MRPL17" "SPHKAP" "MRPL15" "SLC39A14"
[61] "KRT10" "ATP8A2" "PTPRD" "EXOSC8" "TUBA4A" "RDH10"
[67] "NCEH1" "RBFOX1" "TNNI3" "EPHX1" "KDM3B" "TAP1"
[73] "NLGN1" "NPM3" "TP53I3" "EIF2B1" "FHOD3" "PPP1R12B"
[79] "SLC25A15" "TMEM177" "YES1" "LGALS3" "RAB33B" "WHRN"
[85] "FDXR" "TENT5A" "DDAH1" "TCAP" "MYH13" "CASP3"
[91] "NAV1" "MCM5" "TPM4" "TOP2A" "GPC6" "SIDT2"
[97] "BLVRB" "IKBIP" "TNS1" "ZWINT" "ICAM1" "CYP2J2"
[103] "PCNA" "PTPRZ1" "XIRP2" "THEM6" "SCN5A" "CCDC60"
[109] "ARHGAP10" "EPPK1" "ENDOD1" "GPRIN3" "EPSTI1" "MYH7"
[115] "CISD3" "MCM3" "STAT1" "LDB3" "GPX1" "TXNRD1"
[121] "DDAH2" "RAB9B" "SLC16A7" "ITGB1BP2" "BDH1" "LMOD1"
[127] "MYH6" "PLXNA4" "SLC25A12" "FITM1" "DTL" "AQP1"
[133] "ANXA4" "OBSCN" "ATP1A3" "FSIP2" "KRT19" "SLC9A1"
[139] "NRAP" "EI24" "GPX8" "SLC8A1" "MCM2" "MKI67"
[145] "DPF1" "SYNPO2" "DUOX2" "ARMCX2" "CSPG4" "CACNB1"
[151] "CEP170B" "SLC25A40" "MIS18BP1" "H4C8" "H4C5" "H4C15"
[157] "H4C14" "DHODH" "NFIC" "MCAM" "POLQ" "NME3"
[163] "ACYP2" "MCM6" GWAS_Exp <- intersect(Expressed_protein, CAD_GWAS_Expressed)
GWAS_Exp [1] "GIGYF2" "EDNRA" "SNRPD2" "LDLR" "FBN2" "PALLD"
[7] "PTK7" "HTRA1" "COL4A2" "RDX" "AGPAT4" "FN1"
[13] "ANXA6" "CNPY2" "HSD17B12" "WDR11" "RRBP1" "CTAGE1"
[19] "GOSR2" "NIPSNAP3B" "NDUFAF6" "VPS29" "NOC3L" "APOE"
[25] "MRAS" "FGD6" "KANK2" "TNS1" "GIT2" "NRIP1"
[31] "ACAA2" "GFPT1" "MAT2A" "COMT" "SOD2" "ATP2A2"
[37] "MAP1S" "MYL2" "CDH13" "ATP2B1" "BCAP29" "PAFAH1B1"
[43] "SERPINH1" "PPCS" "MIA3" "BCAS3" "HNRNPUL1" "IGF2BP1"
[49] "SORBS2" "SF3A3" "ATP1B1" "ITGA2" "PDLIM5" "RAC1"
[55] "NEK9" "TMEM106B" "CLINT1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 2# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 162# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 55# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3059# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.046477, df = 1, p-value = 0.8293# Low Divergent Gene-Proteins CAD
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Lower_quant == TRUE, ]$hgnc_symbol
Non_DE_Divergent [1] "RPS19" "ECSIT" "TMEM192" "BCAM" "CACNA1D" "VMA21"
[7] "CAPNS1" "MAP1A" "EIF3I" "ERLIN1" "CAPZB" "MAGI2"
[13] "NAPG" "CSRP3" "TBRG4" "RSF1" "NECTIN2" "SAR1A"
[19] "PDHB" "GRSF1" "NPTN" "CDS2" "EIF5A" "EXOSC4"
[25] "KIRREL1" "DCTN1" "APEH" "PDHA1" "NIT2" "TFG"
[31] "PMPCB" "NLN" "RMND1" "SEPTIN7" "DYNLL1" "FH"
[37] "RPA2" "RHOT2" "RPL6" "XXYLT1" "NDUFA7" "EIF3D"
[43] "COLGALT2" "ASAH1" "ANXA7" "ETFDH" "DECR1" "CD81"
[49] "EXTL3" "PDXP" "NSUN2" "MARCHF5" "CPVL" "TXNRD2"
[55] "TMED10" "FLOT2" "CPSF7" "SIN3A" "TOR1AIP2" "ELOB"
[61] "NDUFA13" "LNPEP" "GLB1" "ME2" "XPO1" "GLO1"
[67] "RINT1" "SLC25A22" "PDPR" "ANO6" "PPIC" "EHD4"
[73] "HSP90AB1" "SLC39A6" "NOMO1" "GATB" "MTX1" "SLC25A13"
[79] "VDAC1" "KPNA4" "DDX23" "TRMT6" "DSP" "STXBP2"
[85] "ANK3" "MTIF2" "GRPEL1" "DBT" "CCT2" "CLYBL"
[91] "IST1" "SLC15A4" "OGDH" "CUL1" "RDH14" "ALDH5A1"
[97] "LARS2" "U2AF1" "ABLIM1" "AGPS" "VKORC1L1" "LAMTOR1"
[103] "ZNF777" "NDUFB3" "PTTG1IP" "MRPS11" "DNAJA2" "IPO5"
[109] "GSTM3" "PARL" "ACAD11" "EMC8" "SEC11A" "SNRNP70"
[115] "TAF15" "PPP2CA" "POMK" "NDUFAF1" "IARS2" "TIMM22"
[121] "PELP1" "PTGR3" "SEC24B" "FUNDC2" "ABCC4" "PURA"
[127] "AP3B1" "VCP" "SCO1" "MGAT2" "DOCK7" "LUC7L2"
[133] "PROS1" "CAST" "PPP2R5D" "ODR4" "RCN1" "HCCS"
[139] "CHID1" "RAD23B" "CYP20A1" "PDIA5" "PRPF4" "PRAF2"
[145] "DGUOK" "COX20" "U2SURP" "WDR20" "SCO2" "ECHS1"
[151] "GLRX3" "DCAF8" "PSMC2" "PYROXD2" "HEXA" "PIP5K1A"
[157] "LEMD3" "PRPF40A" "TMEM11" "CYB5B" "SELENOH" "DIXDC1"
[163] "AP1M1" "PTGES3" GWAS_Exp <- intersect(Expressed_protein, CAD_GWAS_Expressed)
GWAS_Exp [1] "GIGYF2" "EDNRA" "SNRPD2" "LDLR" "FBN2" "PALLD"
[7] "PTK7" "HTRA1" "COL4A2" "RDX" "AGPAT4" "FN1"
[13] "ANXA6" "CNPY2" "HSD17B12" "WDR11" "RRBP1" "CTAGE1"
[19] "GOSR2" "NIPSNAP3B" "NDUFAF6" "VPS29" "NOC3L" "APOE"
[25] "MRAS" "FGD6" "KANK2" "TNS1" "GIT2" "NRIP1"
[31] "ACAA2" "GFPT1" "MAT2A" "COMT" "SOD2" "ATP2A2"
[37] "MAP1S" "MYL2" "CDH13" "ATP2B1" "BCAP29" "PAFAH1B1"
[43] "SERPINH1" "PPCS" "MIA3" "BCAS3" "HNRNPUL1" "IGF2BP1"
[49] "SORBS2" "SF3A3" "ATP1B1" "ITGA2" "PDLIM5" "RAC1"
[55] "NEK9" "TMEM106B" "CLINT1" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 0# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 164# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 57# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3057# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 2.0777, df = 1, p-value = 0.1495# High Divergent Gene-Proteins ARR
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Upper_quant == TRUE, ]$hgnc_symbol
Non_DE_Divergent [1] "ANKRD1" "TRIM63" "RRP8" "VASN" "QKI" "MYBBP1A"
[7] "TPBG" "NUCB1" "H1-10" "RCC2" "SLC30A1" "GNL3"
[13] "RPL22L1" "BAD" "FADS2" "FAM120A" "SMC3" "FKBP5"
[19] "LSM2" "BAIAP2" "KDSR" "USP28" "EXOSC10" "ATP6AP2"
[25] "ACLY" "TUBB3" "THBS1" "GJA1" "S1PR1" "CD46"
[31] "PES1" "DPF3" "TRIM54" "POLR1E" "VCAM1" "LMOD2"
[37] "LGR4" "MBNL1" "LRRC10" "CAND2" "SLC1A5" "TKT"
[43] "CCNA1" "RPL36AL" "PAK4" "LRRN4" "MCM8" "FUCA1"
[49] "STIM1" "WDR43" "KLHL31" "LDLR" "TNNT1" "MAGOHB"
[55] "CHCHD6" "TUBB" "MRPL17" "SPHKAP" "MRPL15" "SLC39A14"
[61] "KRT10" "ATP8A2" "PTPRD" "EXOSC8" "TUBA4A" "RDH10"
[67] "NCEH1" "RBFOX1" "TNNI3" "EPHX1" "KDM3B" "TAP1"
[73] "NLGN1" "NPM3" "TP53I3" "EIF2B1" "FHOD3" "PPP1R12B"
[79] "SLC25A15" "TMEM177" "YES1" "LGALS3" "RAB33B" "WHRN"
[85] "FDXR" "TENT5A" "DDAH1" "TCAP" "MYH13" "CASP3"
[91] "NAV1" "MCM5" "TPM4" "TOP2A" "GPC6" "SIDT2"
[97] "BLVRB" "IKBIP" "TNS1" "ZWINT" "ICAM1" "CYP2J2"
[103] "PCNA" "PTPRZ1" "XIRP2" "THEM6" "SCN5A" "CCDC60"
[109] "ARHGAP10" "EPPK1" "ENDOD1" "GPRIN3" "EPSTI1" "MYH7"
[115] "CISD3" "MCM3" "STAT1" "LDB3" "GPX1" "TXNRD1"
[121] "DDAH2" "RAB9B" "SLC16A7" "ITGB1BP2" "BDH1" "LMOD1"
[127] "MYH6" "PLXNA4" "SLC25A12" "FITM1" "DTL" "AQP1"
[133] "ANXA4" "OBSCN" "ATP1A3" "FSIP2" "KRT19" "SLC9A1"
[139] "NRAP" "EI24" "GPX8" "SLC8A1" "MCM2" "MKI67"
[145] "DPF1" "SYNPO2" "DUOX2" "ARMCX2" "CSPG4" "CACNB1"
[151] "CEP170B" "SLC25A40" "MIS18BP1" "H4C8" "H4C5" "H4C15"
[157] "H4C14" "DHODH" "NFIC" "MCAM" "POLQ" "NME3"
[163] "ACYP2" "MCM6" GWAS_Exp <- intersect(Results_RNA_DF_Pro_DF_Merged_NAomit$hgnc_symbol, ARR_GWAS$hgnc_symbol)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 8# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 156# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 36# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3078# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 13.608, df = 1, p-value = 0.0002252fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.001252
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
1.729378 9.793788
sample estimates:
odds ratio
4.380849 GWAS_List_4 <- intersect(Non_DE_Divergent, GWAS_Exp)
GWAS_List_4[1] "DPF3" "LRRC10" "CAND2" "SCN5A" "ARHGAP10" "MYH7" "MYH6"
[8] "ANXA4" # Plot result
colnames(mat) <- c("DE", "~DE")
rownames(mat) <- c("GWAS", "~GWAS")
mat DE ~DE
GWAS 8 36
~GWAS 156 3078table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("GWAS", "Non-GWAS"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
GWAS 8 36
Non-GWAS 156 3078# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("Divergent + GWAS", "Divergent ~ GWAS", "~ Divergent + GWAS", "~ Divergent ~ GWAS")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Low Divergent Gene-Proteins ARR
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Lower_quant == TRUE, ]$hgnc_symbol
Non_DE_Divergent [1] "RPS19" "ECSIT" "TMEM192" "BCAM" "CACNA1D" "VMA21"
[7] "CAPNS1" "MAP1A" "EIF3I" "ERLIN1" "CAPZB" "MAGI2"
[13] "NAPG" "CSRP3" "TBRG4" "RSF1" "NECTIN2" "SAR1A"
[19] "PDHB" "GRSF1" "NPTN" "CDS2" "EIF5A" "EXOSC4"
[25] "KIRREL1" "DCTN1" "APEH" "PDHA1" "NIT2" "TFG"
[31] "PMPCB" "NLN" "RMND1" "SEPTIN7" "DYNLL1" "FH"
[37] "RPA2" "RHOT2" "RPL6" "XXYLT1" "NDUFA7" "EIF3D"
[43] "COLGALT2" "ASAH1" "ANXA7" "ETFDH" "DECR1" "CD81"
[49] "EXTL3" "PDXP" "NSUN2" "MARCHF5" "CPVL" "TXNRD2"
[55] "TMED10" "FLOT2" "CPSF7" "SIN3A" "TOR1AIP2" "ELOB"
[61] "NDUFA13" "LNPEP" "GLB1" "ME2" "XPO1" "GLO1"
[67] "RINT1" "SLC25A22" "PDPR" "ANO6" "PPIC" "EHD4"
[73] "HSP90AB1" "SLC39A6" "NOMO1" "GATB" "MTX1" "SLC25A13"
[79] "VDAC1" "KPNA4" "DDX23" "TRMT6" "DSP" "STXBP2"
[85] "ANK3" "MTIF2" "GRPEL1" "DBT" "CCT2" "CLYBL"
[91] "IST1" "SLC15A4" "OGDH" "CUL1" "RDH14" "ALDH5A1"
[97] "LARS2" "U2AF1" "ABLIM1" "AGPS" "VKORC1L1" "LAMTOR1"
[103] "ZNF777" "NDUFB3" "PTTG1IP" "MRPS11" "DNAJA2" "IPO5"
[109] "GSTM3" "PARL" "ACAD11" "EMC8" "SEC11A" "SNRNP70"
[115] "TAF15" "PPP2CA" "POMK" "NDUFAF1" "IARS2" "TIMM22"
[121] "PELP1" "PTGR3" "SEC24B" "FUNDC2" "ABCC4" "PURA"
[127] "AP3B1" "VCP" "SCO1" "MGAT2" "DOCK7" "LUC7L2"
[133] "PROS1" "CAST" "PPP2R5D" "ODR4" "RCN1" "HCCS"
[139] "CHID1" "RAD23B" "CYP20A1" "PDIA5" "PRPF4" "PRAF2"
[145] "DGUOK" "COX20" "U2SURP" "WDR20" "SCO2" "ECHS1"
[151] "GLRX3" "DCAF8" "PSMC2" "PYROXD2" "HEXA" "PIP5K1A"
[157] "LEMD3" "PRPF40A" "TMEM11" "CYB5B" "SELENOH" "DIXDC1"
[163] "AP1M1" "PTGES3" GWAS_Exp <- intersect(Results_RNA_DF_Pro_DF_Merged_NAomit$hgnc_symbol, ARR_GWAS$hgnc_symbol)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 2# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 162# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 42# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3072# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 6.492e-27, df = 1, p-value = 1# High Divergent Gene-Proteins ARR DE
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Upper_quant == TRUE, ]$hgnc_symbol
GWAS_Exp <- intersect(Results_RNA_DF_Pro_DF_Merged_NAomit$hgnc_symbol, ARR_GWAS$hgnc_symbol)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(Non_DE_Divergent, GWAS_Exp) %>% length()
A[1] 8# B = number of DE gene/proteins that are not in the GWAS list
B <- length(Non_DE_Divergent) - A
B[1] 156# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 36# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(Non_DE_Divergent)) - C
D[1] 3078# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 13.608, df = 1, p-value = 0.0002252# High Divergent Proteins ARR DE
Non_DE_Divergent <- New_RNA_PRO_DF[New_RNA_PRO_DF$Upper_quant == TRUE, ]
DE_Divergent <- Non_DE_Divergent[Non_DE_Divergent$Pro_Pval < 0.05, ]$hgnc_symbol
GWAS_Exp <- intersect(Results_RNA_DF_Pro_DF_Merged_NAomit$hgnc_symbol, ARR_GWAS$hgnc_symbol)
GWAS_Exp [1] "GTF2I" "NUCKS1" "DPF3" "LRRC10" "CAND2" "RBM20"
[7] "FXR2" "HCN4" "NACA" "CASZ1" "CAV1" "HSPG2"
[13] "YWHAE" "SYNPO2L" "XXYLT1" "CFL2" "ASAH1" "CUL4A"
[19] "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B" "MYPN"
[25] "MYH7" "MYO1C" "CAMK2D" "MYH6" "SYNE2" "ANXA4"
[31] "ORMDL3" "TTN" "USP34" "GNB4" "IGF1R" "PKP2"
[37] "SLIT3" "XPO7" "PLN" "PHLDB2" "CASQ2" "SLC27A6"
[43] "CALU" "DEK" # A = number of DE gene/proteins that are in the GWAS list
A <- intersect(DE_Divergent, GWAS_Exp) %>% length()
A[1] 3# B = number of DE gene/proteins that are not in the GWAS list
B <- length(DE_Divergent) - A
B[1] 43# C = number of expressed gene/proteins that are in the GWAS list but are not DE
C <- length(GWAS_Exp) - A
C[1] 41# D = number of expressed gene/proteins that are not in the GWAS list and are not DE
D <- (nrow(Results_RNA_DF_Pro_DF_Merged_NAomit) - length(DE_Divergent)) - C
D[1] 3191# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 5.9006, df = 1, p-value = 0.01514fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.02293
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
1.034867 18.066639
sample estimates:
odds ratio
5.423342 # Record gene set, differentially expressed and divergent.
GWAS_List_5 <- intersect(DE_Divergent, GWAS_Exp)
GWAS_List_5[1] "DPF3" "LRRC10" "CAND2" # Plot result
colnames(mat) <- c("DE", "~DE")
rownames(mat) <- c("GWAS", "~GWAS")
mat DE ~DE
GWAS 3 41
~GWAS 43 3191table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("GWAS", "Non-GWAS"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
GWAS 3 41
Non-GWAS 43 3191# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("In GWAS", "Not in GWAS", "In GWAS", "Not in GWAS")
df_mat$Group <- c("Divergent", "Divergent", "~ Divergent", "~ Divergent")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
GWAS_List_1 [1] "DPF3" "LRRC10" "CAND2" "RBM20" "CASZ1" "YWHAE"
[7] "CUL4A" "MTHFD1" "SCN5A" "ARHGAP10" "IRF2BPL" "MYO18B"
[13] "MYH7" "MYO1C" "CAMK2D" "MYH6" "ANXA4" "TTN"
[19] "USP34" "GNB4" "IGF1R" "PKP2" "SLIT3" "XPO7"
[25] "PHLDB2" "DEK" GWAS_List_2[1] "DPF3" "LRRC10" "CAND2" GWAS_List_3[1] "GTF2I" "SPEN" GWAS_List_4[1] "DPF3" "LRRC10" "CAND2" "SCN5A" "ARHGAP10" "MYH7" "MYH6"
[8] "ANXA4" GWAS_List_5[1] "DPF3" "LRRC10" "CAND2" Mammalian Stress Granule (MSG) Gene-Protein Sets
# Read in data frame curated from (https://msgp.pt/)
MSG <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Data_sets/SG_RBP_AUtoph/MSG.csv", header = TRUE)
# 1. Generate lists of gene-protein pairs with interesting functional genomic properties
#*DE proteins
MSG_DE <- New_RNA_PRO_DF[New_RNA_PRO_DF$Pro_Pval < 0.05, ]
#*DE proteins same sign
MSG_DE_SAME <- New_RNA_PRO_DF[(New_RNA_PRO_DF$sign_match == TRUE) & (New_RNA_PRO_DF$Pro_Pval < 0.05), ]
#*DE proteins opposite sign
MSG_DE_OPPOSITE <- New_RNA_PRO_DF[(New_RNA_PRO_DF$sign_match == FALSE) & (New_RNA_PRO_DF$Pro_Pval < 0.05), ]
#*Divergent proteins
MSG_DIVERGENT <- New_RNA_PRO_DF[ New_RNA_PRO_DF$Upper_quant == TRUE, ]
#*Conserved proteins
MSG_CONSERVED <- New_RNA_PRO_DF[ New_RNA_PRO_DF$Lower_quant == TRUE, ]
#*DE Divergent
MSG_DE_DIVERGENT <- New_RNA_PRO_DF[(New_RNA_PRO_DF$Upper_quant == TRUE) & (New_RNA_PRO_DF$Pro_Pval < 0.05), ]
#*DE Conserved
MSG_DE_Conserved <- New_RNA_PRO_DF[(New_RNA_PRO_DF$Lower_quant == TRUE) & (New_RNA_PRO_DF$Pro_Pval < 0.05), ]
#*DE Protein Expressing RNA
MSG_DE_RNAasprotein <- New_RNA_PRO_DF[(New_RNA_PRO_DF$RNA_Pval < 0.05), ]
#* RNA as
MSG_DE_RNA <- RNA_Seq_Top_Table_24hr[RNA_Seq_Top_Table_24hr$adj.P.Val < 0.05, ]
# 2. Generate sets from MSG data frame
#* MSG (All)
MSG SYMBOL RPB Autophagy Heat_shock Uniprot
1 LC3 FALSE TRUE FALSE Q9H492
2 ZNF638 TRUE FALSE FALSE Q14966
3 ZC3H7B TRUE FALSE FALSE Q9UGR2
4 ZC3H7A TRUE FALSE FALSE Q8IWR0
5 ZC3H14 TRUE FALSE FALSE Q6PJT7
6 YWHAQ FALSE FALSE FALSE P27348
7 YWHAH FALSE FALSE FALSE Q04917
8 YWHAB FALSE FALSE FALSE P31946
9 YTHDF3 TRUE FALSE FALSE Q7Z739
10 YTHDF2 TRUE FALSE FALSE Q9Y5A9
11 YTHDF1 TRUE FALSE FALSE Q9BYJ9
12 YES1 FALSE TRUE FALSE P07947
13 YBX3 TRUE FALSE FALSE P16989
14 YARS TRUE FALSE FALSE P54577
15 VASP FALSE FALSE FALSE P50552
16 USP5 FALSE FALSE FALSE P45974
17 UPF1 TRUE FALSE FALSE Q92900
18 UBL4A FALSE FALSE FALSE P11441
19 UBAP2L TRUE FALSE FALSE Q14157
20 UBAP2 TRUE FALSE FALSE Q5T6F2
21 UBA1 TRUE FALSE FALSE P22314
22 U2AF1 TRUE FALSE FALSE Q01081
23 TXN TRUE FALSE FALSE P10599
24 TUFM TRUE FALSE FALSE P49411
25 TUBB8 FALSE FALSE FALSE Q3ZCM7
26 TUBA4A FALSE FALSE FALSE A8MUB1
27 TUBA3C FALSE FALSE FALSE P0DPH7
28 TSC1 FALSE TRUE FALSE Q92574
29 TRIP6 TRUE FALSE FALSE Q15654
30 TRIM56 TRUE FALSE FALSE Q9BRZ2
31 TRIM25 TRUE FALSE FALSE Q14258
32 TRIM21 TRUE FALSE FALSE P19474
33 TRDMT1 TRUE FALSE FALSE O14717
34 TPT1 TRUE FALSE FALSE P13693
35 TPM2 FALSE FALSE FALSE P07951
36 TOMM34 FALSE FALSE FALSE Q15785
37 TNRC6B TRUE FALSE FALSE Q9UPQ9
38 TNPO2 FALSE FALSE FALSE O14787
39 TNKS1BP1 FALSE FALSE FALSE Q9C0C2
40 TMOD3 FALSE FALSE FALSE Q9NYL9
41 TERT TRUE FALSE FALSE O14746
42 TCP1 TRUE FALSE FALSE P17987
43 TCEA1 FALSE FALSE FALSE P23193
44 ZC3HAV1 TRUE FALSE FALSE Q7Z2W4
45 ZC3H12A TRUE FALSE TRUE Q5D1E8
46 ZBP1 TRUE FALSE TRUE Q9H171
47 YBX1 TRUE FALSE FALSE P67809
48 XRN1 TRUE FALSE TRUE Q8IZH2
49 ZMAT3 TRUE FALSE FALSE Q9HA38
50 WDR62 TRUE FALSE TRUE O43379
51 VCP TRUE TRUE TRUE P55072
52 USP10 TRUE FALSE TRUE Q14694
53 TTP TRUE FALSE FALSE P26651
54 TRAF2 FALSE TRUE TRUE Q12933
55 TNPO1 TRUE FALSE FALSE Q92973
56 TIAR TRUE FALSE TRUE Q01085
57 TIA-1 TRUE FALSE TRUE P31483
58 TDRD3 TRUE FALSE TRUE Q9H7E2
59 TDP-43 TRUE FALSE FALSE Q13148
60 TAF15 TRUE FALSE TRUE Q92804
61 SYNE1 TRUE FALSE FALSE Q8NF91
62 HNRPQ TRUE FALSE TRUE O60506
63 Syk FALSE FALSE FALSE P43405
64 SYCP3 FALSE FALSE FALSE Q8IZU3
65 SUN1 FALSE FALSE FALSE O94901
66 SUGP2 TRUE FALSE FALSE Q8IX01
67 STRAP TRUE FALSE FALSE Q9Y3F4
68 STIP1 TRUE FALSE FALSE P31948
69 STAU2 TRUE FALSE FALSE Q9NUL3
70 STAU1 TRUE FALSE FALSE O95793
71 STAT1 FALSE FALSE FALSE P42224
72 SRSF4 TRUE FALSE FALSE Q08170
73 SRSF3 TRUE FALSE FALSE P84103
74 SRSF1 TRUE FALSE FALSE Q07955
75 SRRT TRUE FALSE FALSE Q9BXP5
76 SRP9 TRUE FALSE TRUE P49458
77 SRP14 TRUE FALSE TRUE P37108
78 SRI FALSE FALSE FALSE P30626
79 NCOA3 TRUE FALSE FALSE Q9Y6Q9
80 SPECC1L FALSE FALSE FALSE Q69YQ0
81 SPATS2L TRUE FALSE FALSE Q9NUQ6
82 SPAG5 FALSE FALSE FALSE Q96R06
83 SORBS1 FALSE FALSE FALSE Q9BX66
84 SNTB2 TRUE FALSE FALSE Q13425
85 SNRPF TRUE FALSE FALSE P62306
86 SND1 TRUE FALSE FALSE Q7KZF4
87 SMU1 FALSE TRUE FALSE B4E3L0
88 SMN TRUE FALSE TRUE Q16637
89 SMG1 TRUE TRUE TRUE Q96Q15
90 SMC4 FALSE FALSE FALSE Q9NTJ3
91 SMAUG TRUE FALSE FALSE Q9UPU9
92 SMARCA1 FALSE FALSE FALSE P28370
93 SIRT6 TRUE FALSE TRUE Q8N6T7
94 SIPA1L1 FALSE FALSE FALSE J3KP19
95 SGNP TRUE FALSE FALSE Q9NUQ6
96 SFRS3 TRUE FALSE FALSE P84103
97 SFPQ TRUE FALSE FALSE P23246
98 SFN FALSE FALSE FALSE P31947
99 SERBP1 TRUE FALSE FALSE Q8NC51
100 SEC24C FALSE TRUE FALSE P53992
101 KHDRBS1 TRUE FALSE FALSE Q07666
102 SAFB2 TRUE FALSE FALSE Q14151
103 S100A9 FALSE FALSE FALSE P06702
104 S100A7A FALSE FALSE FALSE Q86SG5
105 RSL1D1 TRUE FALSE FALSE O76021
106 RPS6KA3 FALSE TRUE FALSE P51812
107 RPS6 TRUE FALSE FALSE P62753
108 RPS3a TRUE FALSE FALSE P61247
109 RPS3 TRUE FALSE FALSE P23396
110 RPS2 TRUE FALSE FALSE P15880
111 RPS19 TRUE FALSE FALSE P39019
112 ROQUIN TRUE FALSE FALSE Q5TC82
113 PSMD2 FALSE FALSE FALSE Q13200
114 ROCK1 FALSE FALSE TRUE Q13464
115 RNH1 FALSE FALSE FALSE P13489
116 RNF214 FALSE FALSE FALSE Q8ND24
117 DDX58 TRUE FALSE FALSE O95786
118 RhoA FALSE FALSE FALSE P61586
119 DHX36 TRUE FALSE TRUE Q9H2U1
120 RGPD3 FALSE FALSE FALSE A6NKT7
121 RFC4 FALSE FALSE FALSE P35249
122 RFC3 FALSE FALSE FALSE P40938
123 RENT2 TRUE FALSE FALSE Q9HAU5
124 RCC2 TRUE FALSE FALSE Q9P258
125 RCC1 FALSE FALSE FALSE P18754
126 RBPMS TRUE FALSE FALSE Q93062
127 RBMS2 TRUE FALSE FALSE Q15434
128 RBMS1 TRUE FALSE FALSE P29558
129 RBM42 TRUE FALSE FALSE Q9BTD8
130 RBM26 TRUE FALSE FALSE Q5T8P6
131 RBM12B TRUE FALSE FALSE Q8IXT5
132 RBFOX2 TRUE FALSE FALSE O43251
133 RBFOX1 TRUE FALSE FALSE Q9NWB1
134 RBBP4 FALSE FALSE FALSE Q09028
135 RAPTOR FALSE TRUE FALSE Q8N122
136 RAP55 TRUE FALSE FALSE Q8ND56
137 RANBP1 FALSE FALSE FALSE P43487
138 RAD21 FALSE FALSE FALSE O60216
139 RACK1 TRUE FALSE FALSE P63244
140 RACGAP1 FALSE FALSE FALSE Q9H0H5
141 RAB1A FALSE TRUE FALSE P62820
142 QKI TRUE FALSE FALSE Q96PU8
143 PYCR1 FALSE FALSE FALSE P32322
144 PXDNL FALSE FALSE FALSE A1KZ92
145 PURB TRUE FALSE FALSE Q96QR8
146 PURA TRUE FALSE FALSE Q00577
147 PUM2 TRUE FALSE FALSE Q8TB72
148 PUM1 TRUE FALSE FALSE Q14671
149 PTK2 FALSE FALSE FALSE Q8IYN9
150 PTGES3 FALSE FALSE FALSE B4DP21
151 PTBP3 TRUE FALSE FALSE O95758
152 DAZAP2 FALSE FALSE FALSE Q15038
153 PRRC2C FALSE FALSE FALSE Q9Y520
154 PRRC2A TRUE FALSE FALSE P48634
155 PRMT5 FALSE FALSE FALSE O14744
156 PRMT1 TRUE TRUE FALSE Q99873
157 PRKRA TRUE FALSE FALSE O75569
158 PRDX6 FALSE FALSE FALSE P30041
159 PRDX1 FALSE FALSE FALSE Q06830
160 PQBP1 FALSE FALSE FALSE O60828
161 PPP2R1A FALSE TRUE FALSE P30153
162 PPP1R18 FALSE FALSE FALSE Q6NYC8
163 PPP1R10 TRUE FALSE FALSE Q96QC0
164 PPME1 FALSE FALSE FALSE Q9Y570
165 PPIP5K1 FALSE FALSE FALSE Q6PFW1
166 POLR2B TRUE FALSE FALSE P30876
167 ATP2C1 FALSE FALSE FALSE P98194
168 PKP3 FALSE FALSE TRUE Q9Y446
169 PKP2 FALSE FALSE FALSE Q99959
170 PKP1 FALSE FALSE TRUE Q13835
171 PKC_a FALSE FALSE TRUE P17252
172 PHLDB2 FALSE FALSE FALSE Q86SQ0
173 PHB2 FALSE FALSE FALSE Q99623
174 PGAM5 FALSE TRUE FALSE Q96HS1
175 PFN2 FALSE FALSE FALSE P35080
176 PFN1 TRUE FALSE TRUE P07737
177 PFDN4 FALSE FALSE FALSE Q9NQP4
178 PELO FALSE FALSE FALSE Protein pelota homolog
179 PDS5B FALSE FALSE FALSE Q9NTI5
180 PDLIM5 FALSE FALSE FALSE Q96HC4
181 PDLIM4 FALSE FALSE FALSE P50479
182 PDLIM1 FALSE FALSE FALSE O00151
183 PDCD6IP FALSE FALSE FALSE Q8WUM4
184 PCNA FALSE FALSE FALSE P12004
185 PCBP2 TRUE FALSE TRUE Q15366
186 PAWR FALSE FALSE FALSE Q96IZ0
187 TNKS FALSE FALSE FALSE O95271
188 PARP15 FALSE FALSE FALSE Q460N3
189 PARP14 TRUE FALSE FALSE Q460N5
190 PARP12 TRUE FALSE FALSE Q9H0J9
191 PARP1 TRUE FALSE FALSE P09874
192 PARG FALSE FALSE FALSE Q86W56
193 PALLD FALSE FALSE FALSE Q8WX93
194 PAK4 FALSE TRUE FALSE O96013
195 PABPC3 FALSE FALSE FALSE Q9H361
196 PABP4 TRUE FALSE FALSE Q13310
197 PABP1 TRUE FALSE TRUE P11940
198 SQSTM1 FALSE TRUE TRUE Q13501
199 L1RE1 TRUE FALSE FALSE Q9UN81
200 OPTN FALSE FALSE FALSE Q96CV9
201 OGG1 FALSE FALSE FALSE O15527
202 OGFOD1 FALSE FALSE FALSE Q8N543
203 NXF1 TRUE FALSE FALSE Q9UBU9
204 NUP98 TRUE FALSE FALSE P52948
205 NUP205 FALSE FALSE FALSE Q92621
206 NUFIP2 TRUE FALSE FALSE Q7Z417
207 NUDC FALSE FALSE FALSE Q9Y266
208 NTMT1 FALSE FALSE FALSE Q9BV86
209 NSUN2 TRUE FALSE FALSE Q08J23
210 NOSIP TRUE FALSE FALSE Q9Y314
211 NOP58 TRUE FALSE FALSE Q9Y2X3
212 NONO TRUE FALSE FALSE Q15233
213 NEXN FALSE FALSE FALSE Q0ZGT2
214 MYO6 TRUE FALSE FALSE Q9UM54
215 mTOR FALSE TRUE FALSE P42345
216 MTHFD1 FALSE FALSE FALSE P11586
217 MSI2 TRUE FALSE FALSE Q96DH6
218 MTHFSD TRUE FALSE FALSE Q2M296
219 MSI1 TRUE FALSE TRUE O43347
220 MSH6 FALSE FALSE FALSE P52701
221 MOV10 TRUE FALSE FALSE Q9HCE1
222 CASC3 TRUE FALSE FALSE O15234
223 MKI67 TRUE FALSE FALSE P46013
224 MFAP1 TRUE FALSE FALSE P55081
225 MEX3C TRUE FALSE FALSE Q5U5Q3
226 MEX3B TRUE FALSE FALSE Q6ZN04
227 MEX3A TRUE FALSE FALSE A1L020
228 METAP1 FALSE FALSE FALSE P53582
229 MCM7 FALSE FALSE FALSE P33993
230 MCM5 FALSE FALSE FALSE P33992
231 MCM4 FALSE FALSE FALSE P33991
232 MBNL TRUE FALSE TRUE Q9NR56
233 MARS FALSE FALSE FALSE P56192
234 MAPRE1 TRUE FALSE FALSE Q15691
235 MAPK8IP3 FALSE FALSE FALSE Q9UPT6
236 MAPK8 FALSE TRUE TRUE P45983
237 MAP4K4 FALSE FALSE FALSE O95819
238 MAP4 TRUE FALSE FALSE P27816
239 MAP2K7 FALSE TRUE TRUE O14733
240 MAGOHB TRUE FALSE FALSE Q96A72
241 MAGED2 FALSE FALSE FALSE Q9UNF1
242 MAGED1 FALSE FALSE FALSE Q9Y5V3
243 MAGEA4 FALSE FALSE FALSE P43358
244 MAEL FALSE FALSE FALSE Q96JY0
245 MACF1 TRUE FALSE FALSE Q9UPN3
246 LUZP1 FALSE FALSE FALSE Q86V48
247 LUC7L TRUE FALSE FALSE Q9NQ29
248 LSM3 TRUE FALSE FALSE P62310
249 LSM14B TRUE FALSE FALSE Q9BX40
250 LSM14A TRUE FALSE FALSE Q8ND56
251 LPP FALSE FALSE FALSE Q93052
252 LMNA FALSE FALSE FALSE P02545
253 Lin28A TRUE FALSE TRUE Q9H9Z2
254 LEMD3 FALSE FALSE FALSE Q9Y2U8
255 LBR TRUE FALSE FALSE Q14739
256 LARP4 TRUE FALSE FALSE Q71RC2
257 LARP1 TRUE FALSE FALSE Q6PKG0
258 KPNB1 TRUE FALSE TRUE Q14974
259 KPNA6 FALSE TRUE FALSE O60684
260 KPNA3 FALSE FALSE TRUE O00505
261 KPNA2 TRUE FALSE TRUE P52292
262 KPNA1 FALSE FALSE TRUE P52294
263 KLC1 FALSE FALSE FALSE Q07866
264 KIF5B FALSE FALSE FALSE P33176
265 KIF23 FALSE FALSE FALSE Q02241
266 KIAA1524 FALSE FALSE FALSE Q8TCG1
267 KHSRP TRUE FALSE FALSE Q92945
268 KHDRBS3 TRUE FALSE FALSE O75525
269 KANK2 FALSE FALSE FALSE Q63ZY3
270 ITGB1 FALSE FALSE FALSE P05556
271 IPO8 FALSE FALSE FALSE O15397
272 IPO7 FALSE FALSE FALSE O95373
273 IP5K TRUE FALSE FALSE Q9H8X2
274 RED FALSE FALSE FALSE Q13123
275 IGF2BP3 TRUE FALSE TRUE O00425
276 IGF2BP2 TRUE FALSE FALSE Q9Y6M1
277 IGF2BP1 TRUE FALSE FALSE Q9NZI8
278 IFIH1 FALSE FALSE TRUE Q9BYX4
279 ELAVL1 TRUE FALSE TRUE Q15717
280 HSPD1 TRUE FALSE FALSE P10809
281 HSPB1 TRUE FALSE TRUE P04792
282 HSPA9 TRUE FALSE FALSE P38646
283 HSPA4 FALSE FALSE FALSE P34932
284 HSP90AA1 TRUE FALSE FALSE P07900
285 HSF1 FALSE FALSE TRUE Q00613
286 HNRPK TRUE FALSE FALSE P61978
287 HNRPA1 TRUE FALSE TRUE P09651
288 HNRNPUL1 TRUE FALSE FALSE Q9BUJ2
289 HNRNPK TRUE FALSE FALSE P61978
290 HNRNPH2 TRUE FALSE FALSE P55795
291 HNRNPAB TRUE FALSE FALSE Q99729
292 HNRNPA3 TRUE FALSE FALSE P51991
293 HNRNPA2B1 TRUE FALSE FALSE P22626
294 HMGN1 FALSE FALSE FALSE P05114
295 HMGB3 TRUE FALSE FALSE O15347
296 HMGA1 FALSE FALSE FALSE P17096
297 HELZ2 TRUE FALSE FALSE Q9BYK8
298 HELZ TRUE FALSE FALSE P42694
299 HDAC6 FALSE TRUE TRUE Q9UBN7
300 HABP4 TRUE FALSE FALSE Q5JVS0
301 H2AFV FALSE FALSE FALSE Q71UI9
302 H1FX TRUE FALSE FALSE Q92522
303 H1F0 TRUE FALSE FALSE P07305
304 GSPT1 TRUE TRUE FALSE P15170
305 GRB7 TRUE FALSE TRUE Q14451
306 GNB2 TRUE FALSE FALSE P62879
307 GLE1 FALSE FALSE TRUE Q53GS7
308 GFPT1 FALSE FALSE FALSE Q06210
309 G3BP2 FALSE FALSE TRUE Q9UN86
310 G3BP1 TRUE FALSE FALSE Q13283
311 FXR2P TRUE FALSE TRUE P51116
312 FXR1 TRUE FALSE TRUE P51114
313 FUS TRUE FALSE TRUE P35637
314 FUBP3 TRUE FALSE FALSE Q96I24
315 FTSJ3 TRUE FALSE FALSE Q8IY81
316 FSCN1 TRUE FALSE FALSE Q16658
317 FNDC3B TRUE FALSE FALSE Q53EP0
318 FMRP TRUE FALSE FALSE Q06787
319 FLNB TRUE FALSE FALSE O75369
320 FHL1 FALSE FALSE FALSE Q13642
321 FBP2 FALSE FALSE FALSE O00757
322 FBP1 FALSE FALSE FALSE P09467
323 FBL TRUE FALSE FALSE P22087
324 FASTK TRUE FALSE TRUE Q14296
325 FAM98A TRUE FALSE FALSE Q8NCA5
326 FAM195B FALSE FALSE FALSE C9JLW8
327 FAM195A FALSE FALSE FALSE Q9BUT9
328 FAM120A TRUE FALSE FALSE Q9NZB2
329 FAK1 FALSE FALSE TRUE Q05397
330 EWS TRUE FALSE TRUE Q01844
331 ETF1 TRUE TRUE FALSE Q96CG1
332 EPPK1 TRUE FALSE FALSE P58107
333 ELAVL4 TRUE FALSE FALSE P26378
334 ELAVL2 TRUE FALSE FALSE Q12926
335 EIF4H TRUE FALSE FALSE Q15056
336 EIF4G2 TRUE FALSE FALSE P78344
337 EIF4G1 TRUE FALSE FALSE Q04637
338 EIF4E TRUE TRUE FALSE P06730
339 EIF4B TRUE FALSE FALSE P23588
340 EIF4A1 TRUE FALSE FALSE P60842
341 EIF3M FALSE FALSE FALSE Q7L2H7
342 EIF3L TRUE FALSE FALSE Q9Y262
343 EIF3K FALSE FALSE FALSE Q9UBQ5
344 EIF3J FALSE FALSE FALSE B4DUI3
345 EIF3I FALSE FALSE FALSE Q13347
346 EIF3H TRUE FALSE FALSE O15372
347 EIF3G TRUE FALSE FALSE O75821
348 EIF3F FALSE FALSE FALSE O00303
349 EIF3E TRUE FALSE FALSE P60228
350 EIF3D TRUE FALSE FALSE O15371
351 EIF3B TRUE FALSE FALSE P55884
352 EIF3A TRUE FALSE FALSE Q14152
353 EIF2S2 TRUE FALSE FALSE P20042
354 EIF2AK2 TRUE TRUE FALSE P19525
355 EIF2AK1 FALSE TRUE FALSE Q9BQI3
356 EIF2A TRUE FALSE FALSE B4DQ14
357 EDC4 FALSE FALSE FALSE Q6P2E9
358 PA2G4 TRUE TRUE TRUE Q9UQ80
359 DZIP1 FALSE FALSE FALSE Q86YF9
360 DYRK3 FALSE FALSE FALSE O43781
361 DYNLL2 FALSE FALSE FALSE Q96FJ2
362 DTX3L TRUE FALSE FALSE Q8TDB6
363 DSTN FALSE FALSE FALSE P60981
364 DST FALSE FALSE FALSE Q03001
365 DSP TRUE FALSE FALSE P15924
366 DPYSL3 FALSE FALSE FALSE Q14195
367 DPYSL2 FALSE FALSE FALSE Q16555
368 DNCI2 FALSE FALSE FALSE Q13409
369 DNAJC8 FALSE FALSE FALSE O75937
370 DKC1 TRUE FALSE FALSE O60832
371 DISC1 FALSE FALSE FALSE Q9NRI5
372 DHX30 TRUE FALSE FALSE Q7L2E3
373 DYNC1H1 TRUE FALSE FALSE Q14204
374 DERA FALSE FALSE FALSE Q9Y315
375 DDX6 TRUE FALSE FALSE P26196
376 DDX50 TRUE FALSE FALSE Q9BQ39
377 DDX47 TRUE FALSE FALSE Q9H0S4
378 DDX3 TRUE FALSE TRUE O00571
379 DDX21 TRUE FALSE FALSE Q9NR30
380 DDX19A TRUE FALSE FALSE Q9NUU7
381 DDX1 TRUE FALSE TRUE Q92499
382 DCTN1 FALSE FALSE FALSE Q14203
383 DCP1A TRUE FALSE FALSE Q9NPI6
384 DCD TRUE FALSE FALSE P81605
385 DAZL TRUE FALSE FALSE Q92904
386 DAZAP1 TRUE FALSE FALSE Q96EP5
387 CWC22 TRUE FALSE FALSE Q9HCG8
388 CELF1 TRUE TRUE TRUE Q92879
389 CTTNBP2NL FALSE FALSE FALSE Q9P2B4
390 CTNND1 FALSE FALSE FALSE O60716
391 CTNNA2 FALSE FALSE FALSE P26232
392 CSTF1 TRUE FALSE FALSE Q05048
393 CSE1L FALSE FALSE FALSE P55060
394 CSDE1 TRUE FALSE FALSE O75534
395 CRYAB FALSE FALSE FALSE P02511
396 SLC6A8 TRUE FALSE TRUE P48029
397 CPSF7 TRUE FALSE FALSE Q8N684
398 CPSF6 TRUE FALSE FALSE Q16630
399 CPSF3 TRUE FALSE FALSE Q9UKF6
400 CPEB1 TRUE FALSE FALSE Q9BZB8
401 CORO1B FALSE FALSE FALSE Q9BR76
402 CNOT1 TRUE FALSE FALSE A5YKK6
403 CNN3 FALSE FALSE FALSE F8WA86
404 CNBP TRUE FALSE FALSE P62633
405 CLIC4 FALSE FALSE FALSE Q9Y696
406 CIT FALSE FALSE FALSE O14578
407 CIRP TRUE FALSE TRUE Q14011
408 CHP1 FALSE FALSE FALSE Q99653
409 CHORDC1 FALSE FALSE FALSE Q9UHD1
410 CHCHD3 FALSE FALSE FALSE Q9NX63
411 CFL1 FALSE FALSE FALSE P23528
412 CERKL FALSE FALSE TRUE Q49MI3
413 CDK2 FALSE TRUE FALSE P24941
414 CDK1 FALSE FALSE FALSE P06493
415 CDC73 FALSE FALSE FALSE Q6P1J9
416 CDC5L TRUE FALSE FALSE Q99459
417 CD24 FALSE FALSE FALSE P25063
418 CCT6A TRUE FALSE FALSE P40227
419 CCT3 FALSE FALSE FALSE B4DUR8
420 CCAR1 TRUE FALSE TRUE Q8IX12
421 CBX1 FALSE FALSE FALSE P83916
422 CBFB FALSE FALSE FALSE Q13951
423 CARHSP1 FALSE FALSE FALSE Q9Y2V2
424 CAPZA2 FALSE FALSE FALSE P47755
425 Caprin-1 TRUE FALSE FALSE Q14444
426 CAP1 FALSE TRUE FALSE Q01518
427 CALR3 FALSE FALSE FALSE Q96L12
428 CALML5 FALSE FALSE FALSE Q9NZT1
429 C9ORF72 FALSE FALSE TRUE Q96LT7
430 RTCB TRUE FALSE FALSE Q9Y3I0
431 CCDC9B TRUE FALSE FALSE Q6ZUT6
432 RTRAF TRUE FALSE FALSE Q9Y224
433 BRF2 FALSE FALSE TRUE Q9HAW0
434 BRF1 FALSE FALSE FALSE Q92994
435 BRAT1 FALSE FALSE FALSE Q6PJG6
436 BANF1 FALSE FALSE FALSE O75531
437 BAG3 FALSE TRUE FALSE O95817
438 HNRNPD TRUE FALSE FALSE Q14103
439 Atx2-L TRUE FALSE FALSE Q8WWM7
440 Atx2 TRUE FALSE TRUE Q99700
441 ATP5F1A TRUE FALSE FALSE P25705
442 ATAD3A FALSE FALSE FALSE Q9NVI7
443 ATAD2 FALSE FALSE FALSE Q6PL18
444 ARPC1B FALSE FALSE FALSE O15143
445 APOBEC3G TRUE FALSE FALSE Q9HC16
446 APEX1 TRUE FALSE FALSE P27695
447 ANXA7 FALSE FALSE FALSE P20073
448 ANXA6 FALSE FALSE FALSE P08133
449 ANXA1 TRUE FALSE FALSE P04083
450 ANP32E FALSE FALSE FALSE Q9BTT0
451 ANG TRUE FALSE FALSE P03950
452 ALDH18A1 TRUE FALSE FALSE P54886
453 AKAP9 FALSE FALSE TRUE Q99996
454 Ago2 TRUE FALSE FALSE Q9UKV8
455 Ago1 TRUE FALSE FALSE Q9UL18
456 ADAR1 TRUE FALSE FALSE P55265
457 ACTR1B FALSE FALSE FALSE P42025
458 ACTR1A FALSE FALSE FALSE P61163
459 ACTBL2 FALSE TRUE FALSE Q562R1
NAME
1 Microtubule associated protein 1 light chain 3 alpha
2 Zinc finger protein 638
3 Zinc finger CCCH domain-containing protein 7B
4 Zinc finger CCCH domain-containing protein 7A
5 Zinc finger CCCH domain-containing protein 14
6 14-3-3 protein theta
7 14-3-3 protein eta
8 14-3-3 protein beta/alpha
9 YTH domain family protein 3
10 YTH domain family protein 2
11 YTH domain family protein 1
12 Tyrosine-protein kinase Yes
13 Y-box-binding protein 3
14 Tyrosine--tRNA ligase, cytoplasmic
15 Vasodilator-stimulated phosphoprotein
16 Ubiquitin carboxyl-terminal hydrolase 5
17 Regulator of nonsense transcripts 1
18 Ubiquitin-like protein 4A
19 Ubiquitin-associated protein 2-like
20 Ubiquitin-associated protein 2
21 Ubiquitin-like modifier-activating enzyme 1
22 Splicing factor U2AF 35 kDa subunit
23 Thioredoxin
24 Elongation factor Tu, mitochondrial
25 Tubulin beta-8 chain
26 Tubulin alpha-4A chain
27 Tubulin alpha-3C/D chain
28 Hamartin
29 Thyroid receptor-interacting protein 6
30 E3 ubiquitin-protein ligase TRIM56
31 E3 ubiquitin/ISG15 ligase TRIM25
32 E3 ubiquitin-protein ligase TRIM21
33 tRNA (cytosine(38)-C(5))-methyltransferase
34 Translationally-controlled tumor protein
35 Tropomyosin beta chain
36 Mitochondrial import receptor subunit TOM34
37 Trinucleotide repeat-containing gene 6B protein
38 Transportin-2
39 182 kDa tankyrase-1-binding protein
40 Tropomodulin-3
41 Telomerase reverse transcriptase
42 T-complex protein 1 subunit alpha
43 Transcription elongation factor A protein 1
44 Zinc finger CCCH-type antiviral protein 1
45 Endoribonuclease ZC3H12A
46 Z-DNA-binding protein 1
47 Nuclease-sensitive element-binding protein 1
48 5'-3' exoribonuclease 1
49 Zinc finger matrin-type protein 3
50 WD repeat-containing protein 62
51 Transitional endoplasmic reticulum ATPase
52 Ubiquitin carboxyl-terminal hydrolase 10
53 Tristetraprolin
54 TNF receptor-associated factor 2
55 Transportin-1
56 TIA-1-related
57 T-cell intracellular antigen-1
58 Tudor domain-containing protein 3
59 TAR DNA-binding protein 43
60 TATA-binding protein-associated factor 2N
61 Nesprin-1
62 Heterogeneous nuclear ribonucleoprotein Q
63 Tyrosine-protein kinase SYK
64 Synaptonemal complex protein 3
65 SUN domain-containing protein 1
66 SURP and G-patch domain-containing protein 2
67 Serine-threonine kinase receptor-associated protein
68 Stress-induced-phosphoprotein 1
69 Double-stranded RNA-binding protein Staufen homolog 2
70 Double-stranded RNA-binding protein Staufen homolog 1
71 Signal transducer and activator of transcription 1-alpha/beta
72 Serine/arginine-rich splicing factor 4
73 Serine/arginine-rich splicing factor 3
74 Serine/arginine-rich splicing factor 1
75 Serrate RNA effector molecule homolog
76 Signal recognition particle 9 kDa protein
77 Signal recognition particle 14 kDa protein
78 Sorcin
79 Nuclear receptor coactivator 3
80 Cytospin-A
81 SPATS2-like protein
82 Sperm-associated antigen 5
83 Sorbin and SH3 domain-containing protein 1
84 Beta-2-syntrophin
85 Small nuclear ribonucleoprotein F
86 Staphylococcal nuclease domain-containing protein 1
87 WD40 repeat-containing protein SMU1
88 Survival motor neuron protein
89 Serine/threonine-protein kinase SMG1
90 Structural maintenance of chromosomes protein
91 Protein Smaug homolog 1
92 Probable global transcription activator SNF2L1
93 NAD-dependent protein deacetylase sirtuin-6
94 Signal-induced proliferation-associated 1-like protein 1
95 SPATS2-like protein
96 RNA binding ,sequence-specific mRNA binding
97 Splicing factor, proline- and glutamine-rich
98 14-3-3 protein sigma
99 Plasminogen activator inhibitor 1 RNA-binding protein
100 Protein transport protein Sec24C
101 KH domain-containing, RNA-binding, signal transduction-associated protein 1
102 Scaffold attachment factor B2
103 Protein S100-A9
104 Protein S100-A7A
105 Ribosomal L1 domain-containing protein 1
106 Ribosomal protein S6 kinase alpha-3
107 40S ribosomal protein S6
108 40S ribosomal protein S3a
109 40S ribosomal protein S3
110 40S ribosomal protein S2
111 40S ribosomal protein S19
112 Roquin-1
113 26S proteasome non-ATPase regulatory subunit 2
114 Rho-associated protein kinase 1
115 Ribonuclease inhibitor
116 RING finger protein 214
117 Probable ATP-dependent RNA helicase DDX58
118 Transforming protein RhoA
119 ATP-dependent RNA helicase DHX36
120 RanBP2-like and GRIP domain-containing protein 3
121 Replication factor C subunit 4
122 Replication factor C subunit 3
123 Regulator of nonsense transcripts 2
124 Regulator of chromosome condensation 2
125 Regulator of chromosome condensation 1
126 RNA-binding protein with multiple splicing
127 RNA-binding motif, single-stranded-interacting protein 2
128 RNA-binding motif, single-stranded-interacting protein 1
129 RNA-binding protein 42
130 RNA-binding protein 26
131 RNA-binding protein 12B
132 RNA binding protein fox-1 homolog 2
133 RNA binding protein fox-1 homolog 1
134 Histone-binding protein RBBP4
135 Regulatory-associated protein of mTOR
136 Protein LSM14 homolog A
137 Ran-specific GTPase-activating protein
138 Double-strand-break repair protein rad21 homolog
139 Receptor of activated protein C kinase 1
140 Rac GTPase-activating protein 1
141 Ras-related protein Rab-1A
142 Protein quaking
143 Pyrroline-5-carboxylate reductase
144 Peroxidasin-like protein
145 Transcriptional activator protein Pur-beta
146 Transcriptional activator protein Pur-alpha
147 Pumilio homolog 2
148 Pumilio homolog 1
149 Focal adhesion kinase 1
150 Prostaglandin E synthase 3
151 Polypyrimidine tract-binding protein 3
152 DAZ-associated protein 2
153 Protein PRRC2C
154 Protein PRRC2A
155 Protein arginine N-methyltransferase 5
156 Protein arginine N-methyltransferase 1
157 Interferon-inducible double-stranded RNA-dependent protein kinase activator A
158 Peroxiredoxin-6
159 Peroxiredoxin-1
160 Polyglutamine-binding protein 1
161 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
162 Phostensin
163 Serine/threonine-protein phosphatase 1 regulatory subunit 10
164 Protein phosphatase methylesterase 1
165 Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1
166 DNA-directed RNA polymerase
167 Calcium-transporting ATPase type 2C member 1
168 Plakophilin-3
169 Plakophilin-2
170 Plakophilin-1
171 Protein kinase C alpha type
172 Pleckstrin homology-like domain family B member 2
173 Prohibitin-2
174 Serine/threonine-protein phosphatase PGAM5, mitochondrial
175 Profilin
176 Profilin-1
177 Prefoldin subunit 4
178 Protein pelota homolog
179 Sister chromatid cohesion protein PDS5 homolog B
180 PDZ and LIM domain protein 5
181 PDZ and LIM domain protein 4
182 PDZ and LIM domain protein 1
183 Programmed cell death 6-interacting protein
184 Proliferating cell nuclear antigen
185 Poly(rC)-binding protein 2
186 PRKC apoptosis WT1 regulator protein
187 Tankyrase-1
188 Poly [ADP-ribose] polymerase 15
189 Poly [ADP-ribose] polymerase 14
190 Poly [ADP-ribose] polymerase 12
191 Poly [ADP-ribose] polymerase 1
192 Poly(ADP-ribose) glycohydrolase
193 Palladin
194 Serine/threonine-protein kinase PAK 4
195 Polyadenylate-binding protein 3
196 Polyadenylate-binding protein 4
197 Polyadenylate-binding protein 1
198 Sequestosome-1
199 LINE-1 retrotransposable element ORF1 protein
200 Optineurin
201 N-glycosylase/DNA lyase
202 Prolyl 3-hydroxylase OGFOD1
203 Nuclear RNA export factor 1
204 Nuclear pore complex protein Nup98-Nup96
205 Nuclear pore complex protein Nup205
206 Nuclear fragile X mental retardation-interacting protein 2
207 Nuclear migration protein nudC
208 N-terminal Xaa-Pro-Lys N-methyltransferase 1
209 tRNA (cytosine(34)-C(5))-methyltransferase
210 Nitric oxide synthase-interacting protein
211 Nucleolar protein 58
212 Non-POU domain-containing octamer-binding protein
213 Nexilin
214 Unconventional myosin-VI
215 Mammalian target of rapamycin
216 C-1-tetrahydrofolate synthase, cytoplasmic
217 RNA-binding protein Musashi homolog 2
218 Methenyltetrahydrofolate synthase domain-containing protein
219 RNA-binding protein Musashi homolog 1
220 DNA mismatch repair protein Msh6
221 Putative helicase MOV-10
222 Protein CASC3
223 Antigen KI-67
224 Microfibrillar-associated protein 1
225 RNA-binding E3 ubiquitin-protein ligase MEX3C
226 RNA-binding protein MEX3B
227 RNA-binding protein MEX3A
228 Methionine aminopeptidase 1
229 DNA replication licensing factor MCM7
230 DNA replication licensing factor MCM5
231 DNA replication licensing factor MCM4
232 Muscleblind-like protein 1
233 Methionine--tRNA ligase, cytoplasmic
234 Microtubule-associated protein RP/EB family member 1
235 C-Jun-amino-terminal kinase-interacting protein 3
236 Mitogen-activated protein kinase 8
237 Mitogen-activated protein kinase kinase kinase kinase 4
238 Microtubule-associated protein 4
239 Dual specificity mitogen-activated protein kinase kinase 7
240 Protein mago nashi homolog 2
241 Melanoma-associated antigen D2
242 Melanoma-associated antigen D1
243 Melanoma-associated antigen 4
244 Protein maelstrom homolog
245 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5
246 Leucine zipper protein 1
247 Putative RNA-binding protein Luc7-like 1
248 U6 snRNA-associated Sm-like protein LSm3
249 Protein LSM14 homolog B
250 Protein LSM14 homolog A
251 Lipoma-preferred partner
252 Prelamin-A/C
253 Protein lin-28 homolog A
254 Inner nuclear membrane protein Man1
255 Lamin-B receptor
256 La-related protein 4
257 La-related protein 1
258 Importin subunit beta-1
259 Importin subunit alpha-7
260 Importin subunit alpha-4
261 Importin subunit alpha-1
262 Importin subunit alpha-5
263 Kinesin light chain 1
264 Kinesin-1 heavy chain
265 Kinesin-like protein KIF23
266 Protein CIP2A
267 Far upstream element-binding protein 2
268 KH domain-containing, RNA-binding, signal transduction-associated protein 3
269 KN motif and ankyrin repeat domain-containing protein 2
270 Integrin beta-1
271 Importin-8
272 Importin-7
273 Inositol-pentakisphosphate 2-kinase
274 Protein Red
275 Insulin-like growth factor 2 mRNA-binding protein 3
276 Insulin-like growth factor 2 mRNA-binding protein 2
277 Insulin-like growth factor 2 mRNA-binding protein 1
278 Interferon-induced helicase C domain-containing protein 1
279 ELAV-like protein 1
280 60 kDa heat shock protein, mitochondrial
281 Heat shock protein beta-1
282 Stress-70 protein, mitochondrial
283 Heat shock 70 kDa protein 4
284 Heat shock protein HSP 90-alpha
285 Heat shock factor protein 1
286 Heterogeneous nuclear ribonucleoprotein K
287 Heterogeneous nuclear ribonucleoprotein A1
288 Heterogeneous nuclear ribonucleoprotein U-like protein 2
289 Heterogeneous nuclear ribonucleoprotein K
290 Heterogeneous nuclear ribonucleoprotein H2
291 Heterogeneous nuclear ribonucleoprotein A/B
292 Heterogeneous nuclear ribonucleoprotein A3
293 Heterogeneous nuclear ribonucleoproteins A2/B1
294 Non-histone chromosomal protein HMG-14
295 High mobility group protein B3
296 High mobility group protein HMG-I/HMG-Y
297 Helicase with zinc finger domain 2
298 Probable helicase with zinc finger domain
299 Histone deacetylase 6
300 Intracellular hyaluronan-binding protein 4
301 Histone H2A.V
302 Histone H1x
303 Histone H1.0
304 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A
305 Growth factor receptor-bound protein 7
306 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
307 Nucleoporin GLE1
308 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
309 Ras GTPase-activating protein-binding protein 2
310 Ras GTPase-activating protein-binding protein 1
311 Fragile X mental retardation syndrome-related protein 2
312 Fragile X mental retardation syndrome-related protein 1
313 Fused in Sarcoma
314 Far upstream element-binding protein 3
315 pre-rRNA processing protein FTSJ3
316 Fascin
317 Fibronectin type III domain-containing protein 3B
318 Fragile X mental retardation protein
319 Filamin-B
320 Four and a half LIM domains protein 1
321 Fructose-1,6-bisphosphatase isozyme 2
322 Fructose-1,6-bisphosphatase 1
323 rRNA 2-O-methyltransferase fibrillarin
324 Fas-activated serine/threonine kinase
325 Protein FAM98A
326 MAPK regulated corepressor interacting protein 1
327 MAPK regulated corepressor interacting protein 2
328 Constitutive coactivator of PPAR-gamma-like protein 1
329 Focal adhesion kinase 1
330 RNA-binding protein EWS
331 Eukaryotic peptide chain release factor subunit 1
332 Epiplakin
333 ELAV-like protein 4
334 ELAV-like protein 2
335 Eukaryotic translation initiation factor 4H
336 Eukaryotic translation initiation factor 4 gamma 2
337 Eukaryotic translation initiation factor 4 gamma 1
338 Eukaryotic translation initiation factor 4E
339 Eukaryotic translation initiation factor 4B
340 Eukaryotic initiation factor 4A-I
341 Eukaryotic translation initiation factor 3 subunit M
342 Eukaryotic translation initiation factor 3 subunit L
343 Eukaryotic translation initiation factor 3 subunit K
344 Eukaryotic translation initiation factor 3 subunit J
345 Eukaryotic translation initiation factor 3 subunit I
346 Eukaryotic translation initiation factor 3 subunit H
347 Eukaryotic translation initiation factor 3 subunit G
348 Eukaryotic translation initiation factor 3 subunit F
349 Eukaryotic translation initiation factor 3 subunit E
350 Eukaryotic translation initiation factor 3 subunit D
351 Eukaryotic translation initiation factor 3 subunit B
352 Eukaryotic translation initiation factor 3 subunit A
353 Eukaryotic translation initiation factor 2 subunit 2
354 Interferon-induced, double-stranded RNA-activated protein kinase
355 Eukaryotic translation initiation factor 2-alpha kinase 1
356 Eukaryotic translation initiation factor 2A
357 Enhancer of mRNA-decapping protein 4
358 Proliferation-associated protein 2G4
359 Zinc finger protein DZIP1
360 Dual specificity tyrosine-phosphorylation-regulated kinase 3
361 Dynein light chain 2, cytoplasmic
362 E3 ubiquitin-protein ligase DTX3L
363 Destrin
364 Dystonin
365 Desmoplakin
366 Dihydropyrimidinase-related protein 3
367 Dihydropyrimidinase-related protein 2
368 Cytoplasmic dynein 1 intermediate chain 2
369 DnaJ homolog subfamily C member 8
370 H/ACA ribonucleoprotein complex subunit 4
371 Disrupted in schizophrenia 1 protein
372 Putative ATP-dependent RNA helicase DHX30
373 Cytoplasmic dynein 1 heavy chain 1
374 Deoxyribose-phosphate aldolase
375 Probable ATP-dependent RNA helicase DDX6
376 ATP-dependent RNA helicase DDX50
377 Probable ATP-dependent RNA helicase DDX47
378 ATP-dependent RNA helicase DDX3X
379 Nucleolar RNA helicase 2
380 ATP-dependent RNA helicase DDX19A
381 ATP-dependent RNA helicase DDX1
382 Dynactin subunit 1
383 mRNA-decapping enzyme 1A
384 Dermcidin
385 Deleted in azoospermia-like
386 DAZ-associated protein 1
387 Pre-mRNA-splicing factor CWC22 homolog
388 CUGBP Elav-like family member 1
389 CTTNBP2 N-terminal-like protein
390 Catenin delta-1
391 Catenin alpha-2
392 Cleavage stimulation factor subunit 1
393 Exportin-2
394 Cold shock domain-containing protein E1
395 Alpha-crystallin B chain
396 Sodium- and chloride-dependent creatine transporter 1
397 Cleavage and polyadenylation specificity factor subunit 7
398 Cleavage and polyadenylation specificity factor subunit 6
399 Cleavage and polyadenylation specificity factor subunit 3
400 Cytoplasmic polyadenylation element-binding protein 1
401 Coronin-1B
402 CCR4-NOT transcription complex subunit 1
403 Calponin-3
404 Cellular nucleic acid-binding protein
405 Chloride intracellular channel protein 4
406 Citron Rho-interacting kinase
407 Cold-inducible RNA-binding protein
408 Calcineurin B homologous protein 1
409 Cysteine and histidine-rich domain-containing protein 1
410 MICOS complex subunit MIC19
411 Cofilin-1
412 Ceramide kinase-like protein
413 Cyclin-dependent kinase 2
414 Cyclin-dependent kinase 1
415 Parafibromin
416 Cell division cycle 5-like protein
417 Signal transducer CD24
418 T-complex protein 1 subunit zeta
419 T-complex protein 1 subunit gamma
420 Cell division cycle and apoptosis regulator protein 1
421 Chromobox protein homolog 1
422 Core-binding factor subunit beta
423 Calcium-regulated heat stable protein 1
424 F-actin-capping protein subunit alpha-2
425 Caprin-1
426 Adenylyl cyclase-associated protein 1
427 Calreticulin-3
428 Calmodulin-like protein 5
429 Guanine nucleotide exchange C9orf72
430 tRNA-splicing ligase RtcB homolog
431 Coiled-coil domain containing 9B
432 RNA transcription, translation and transport factor
433 Transcription factor IIIB 50 kDa subunit
434 Transcription factor IIIB 90 kDa subunit
435 BRCA1-associated ATM activator 1
436 Barrier-to-autointegration factor
437 BAG family molecular chaperone regulator 3
438 Heterogeneous nuclear ribonucleoprotein D0
439 Ataxin-2-like protein
440 Ataxin-2
441 ATP synthase subunit alpha, mitochondrial
442 ATPase family AAA domain-containing protein 3A
443 ATPase family AAA domain-containing protein 2
444 Actin-related protein 2/3 complex subunit 1B
445 DNA dC->dU-editing enzyme APOBEC-3G
446 DNA-(apurinic or apyrimidinic site) lyase
447 Annexin A7
448 Annexin A6
449 Annexin A1
450 Acidic leucine-rich nuclear phosphoprotein 32 family member E
451 Angiogenin
452 Delta-1-pyrroline-5-carboxylate synthase
453 A-kinase anchor protein 9
454 Protein argonaute-2
455 Protein argonaute-1
456 Double-stranded RNA-specific adenosine deaminase
457 Beta-centractin
458 Alpha-centractin
459 Beta-actin-like protein 2#* RPB
MSG_RPB <- MSG[MSG$RPB == TRUE, ]
#* Autophagy
MSG_Auto <- MSG[MSG$Autophagy == TRUE, ]
#* Heat shock
MSG_HSP <- MSG[MSG$Heat_shock == TRUE, ]
#* RPB-Autophagy
MSG_RPB_Auto <- MSG[(MSG$RPB == TRUE) & (MSG$Autophagy == TRUE), ]
#* RPB-Heat shock
MSG_RPB_HSP <- MSG[(MSG$RPB == TRUE) & (MSG$Heat_shock == TRUE), ]
#* Autophagy Heat_shock
MSG_Auto_HSP <- MSG[(MSG$Autophagy == TRUE) & (MSG$Heat_shock == TRUE), ]Testing MSG Enrichment
####* ——— DE Proteins ####
SAME_Sign_DE <- MSG_DE
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 43# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 174# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 228# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2833# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 39.252, df = 1, p-value = 3.725e-10fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 2.225e-08
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
2.088190 4.437598
sample estimates:
odds ratio
3.069105 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 43 228
Non-MSG 174 2833# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 36# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 181# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 132# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2929# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 60.319, df = 1, p-value = 8.068e-15fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 6.682e-11
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
2.874198 6.639167
sample estimates:
odds ratio
4.409909 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 36 132
Non-RPB 181 2929# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 2# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 215# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 16# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3045# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.08596, df = 1, p-value = 0.7694fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.3368
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.1961725 7.6061265
sample estimates:
odds ratio
1.769951 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 2 16
Non-Autophagy 215 3045# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 4# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 213# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 30# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3031# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.7503, df = 1, p-value = 0.3864fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2808
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.4810595 5.4548711
sample estimates:
odds ratio
1.896921 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 4 30
Non-HSP 213 3031# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— DE_SAME Proteins ####
SAME_Sign_DE <- MSG_DE_SAME
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 19# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 65# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 252# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2942# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 21.512, df = 1, p-value = 3.515e-06fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 3.415e-05
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
1.899717 5.869230
sample estimates:
odds ratio
3.410534 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 19 252
Non-MSG 65 2942# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_SAME
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 17# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 67# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 151# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3043# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 37.368, df = 1, p-value = 9.78e-10fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 6.602e-07
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
2.741786 9.064530
sample estimates:
odds ratio
5.107721 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 17 151
Non-RPB 67 3043# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_SAME
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 0# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 84# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 18# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3176# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.5714e-26, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.000000 8.768482
sample estimates:
odds ratio
0 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 0 18
Non-Autophagy 84 3176# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_SAME
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 2# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 82# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 32# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3162# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.47053, df = 1, p-value = 0.4927fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2161
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.2751799 9.7207609
sample estimates:
odds ratio
2.409026 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 2 32
Non-HSP 82 3162# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— DE_OPPOSSITE Proteins ####
SAME_Sign_DE <- MSG_DE_OPPOSITE
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 24# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 109# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 247# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2898# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 16.158, df = 1, p-value = 5.827e-05fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.0002715
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
1.556627 4.136866
sample estimates:
odds ratio
2.582298 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 24 247
Non-MSG 109 2898# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_OPPOSITE
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 19# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 114# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 149# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2996# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 22.001, df = 1, p-value = 2.725e-06fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 3.247e-05
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
1.892256 5.657692
sample estimates:
odds ratio
3.349195 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 19 149
Non-RPB 114 2996# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_OPPOSITE
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 2# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 131# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 16# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3129# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.85012, df = 1, p-value = 0.3565fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.1641
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.329514 12.903134
sample estimates:
odds ratio
2.984005 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 2 16
Non-Autophagy 131 3129# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_OPPOSITE
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 2# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 131# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 32# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3113# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.011086, df = 1, p-value = 0.9161fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.6472
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.1706117 5.9286977
sample estimates:
odds ratio
1.484973 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 2 32
Non-HSP 131 3113# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— Divergent Proteins ####
SAME_Sign_DE <- MSG_DIVERGENT
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 14# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 150# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 257# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2857# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.4936e-27, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.8841
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.5457198 1.8294807
sample estimates:
odds ratio
1.037558 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 14 257
Non-MSG 150 2857# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DIVERGENT
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 9# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 155# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 159# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2955# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.0011882, df = 1, p-value = 0.9725fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.8549
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.475293 2.155860
sample estimates:
odds ratio
1.079133 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 9 159
Non-RPB 155 2955# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DIVERGENT
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 2# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 162# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 16# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3098# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.42236, df = 1, p-value = 0.5158fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2265
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.2643467 10.2993716
sample estimates:
odds ratio
2.389435 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 2 16
Non-Autophagy 162 3098# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DIVERGENT
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 1# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 163# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 33# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3081# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.025273, df = 1, p-value = 0.8737fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.01399836 3.46785703
sample estimates:
odds ratio
0.5728478 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 1 33
Non-HSP 163 3081# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— Conserved Proteins ####
SAME_Sign_DE <- MSG_CONSERVED
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 13# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 151# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 258# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2856# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.00028735, df = 1, p-value = 0.9865fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.488926 1.710323
sample estimates:
odds ratio
0.9530368 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 13 258
Non-MSG 151 2856# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_CONSERVED
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 9# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 155# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 159# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2955# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.0011882, df = 1, p-value = 0.9725fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.8549
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.475293 2.155860
sample estimates:
odds ratio
1.079133 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 9 159
Non-RPB 155 2955# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_CONSERVED
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 1# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 163# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 17# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3097# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.632e-26, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.604
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.0265821 7.2196283
sample estimates:
odds ratio
1.117607 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 1 17
Non-Autophagy 163 3097# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_CONSERVED
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 2# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 162# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 32# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3082# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 8.5267e-29, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.6868
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.1368935 4.7306691
sample estimates:
odds ratio
1.188974 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 2 32
Non-HSP 162 3082# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— DE_Divergent Proteins ####
SAME_Sign_DE <- MSG_DE_DIVERGENT
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 6# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 40# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 265# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 2967# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.83733, df = 1, p-value = 0.3602fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2712
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.5764723 4.0352669
sample estimates:
odds ratio
1.679099 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 6 265
Non-MSG 40 2967# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_DIVERGENT
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 5# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 41# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 163# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3069# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 2.0814, df = 1, p-value = 0.1491fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.08388
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.6985551 5.9147209
sample estimates:
odds ratio
2.295329 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 5 163
Non-RPB 41 3069# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_DIVERGENT
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 1# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 45# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 17# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3215# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.24713, df = 1, p-value = 0.6191fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2251
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.09840033 27.96699643
sample estimates:
odds ratio
4.19864 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 1 17
Non-Autophagy 45 3215# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_DIVERGENT
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 1# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 45# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 33# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3199# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.0011245, df = 1, p-value = 0.9732fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.383
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.05181826 13.47403454
sample estimates:
odds ratio
2.153496 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 1 33
Non-HSP 45 3199# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— DE_Conserved Proteins ####
SAME_Sign_DE <- MSG_CONSERVED[MSG_CONSERVED$Pro_Pval < 0.05, ]
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 1# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 2# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 270# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3005# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.27934, df = 1, p-value = 0.5971fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.2281
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.0939785 107.1277515
sample estimates:
odds ratio
5.559027 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 1 270
Non-MSG 2 3005# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_CONSERVED[MSG_CONSERVED$Pro_Pval < 0.05, ]
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 1# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 2# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 167# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3108# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 0.82262, df = 1, p-value = 0.3644fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.146
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.1567954 179.1527889
sample estimates:
odds ratio
9.289447 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 1 167
Non-RPB 2 3108# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_CONSERVED[MSG_CONSERVED$Pro_Pval < 0.05, ]
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 0# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 3# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 18# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3257# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 6.1628e-25, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.000 454.648
sample estimates:
odds ratio
0 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 0 18
Non-Autophagy 3 3257# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_CONSERVED[MSG_CONSERVED$Pro_Pval < 0.05, ]
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 0# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 3# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 34# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 3241# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)Warning in chisq.test(mat): Chi-squared approximation may be incorrect
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 8.3091e-30, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.0000 234.5967
sample estimates:
odds ratio
0 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 0 34
Non-HSP 3 3241# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####* ——— DE_RNA In Expressed Protein Set ####
SAME_Sign_DE <- MSG_DE_RNAasprotein
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# 1. MSG (All)
#**************************
MSG_Exp <- intersect(Expressed_protein, MSG$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q13123" "Q92522" "Q14694" "Q9NR30"
[9] "Q9P258" "Q9NZB2" "Q6P1J9" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753"
[17] "P30876" "Q7Z739" "Q8NC51" "Q99459" "P34932" "Q14966" "Q06830" "P61247"
[25] "P29558" "Q99873" "O00571" "Q71RC2" "P11940" "Q9H0S4" "Q16658" "Q13310"
[33] "Q9NR56" "P39019" "P63244" "Q9BR76" "Q9Y224" "O96013" "Q14444" "Q13283"
[41] "P23396" "P19474" "Q16555" "O00303" "P15880" "Q8WWM7" "O60828" "O60832"
[49] "P62633" "P28370" "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8"
[57] "Q92900" "Q92945" "Q8WX93" "P52701" "Q9Y520" "Q14195" "P37108" "Q07666"
[65] "Q71UI9" "P55265" "P22087" "P55884" "Q9UN86" "P49458" "P23528" "Q8IX01"
[73] "O60506" "P35637" "Q14152" "Q6PJT7" "P07305" "Q99653" "Q13347" "Q9NWB1"
[81] "Q15366" "Q9UBU9" "P17252" "Q13642" "O75569" "Q8NCA5" "O60716" "P22314"
[89] "P23246" "P17096" "P15170" "Q14157" "Q01518" "Q7L2E3" "O15372" "P07737"
[97] "Q9UBQ5" "Q93052" "Q15233" "Q01085" "P05556" "Q8ND56" "Q03001" "P45974"
[105] "Q9NX63" "P13489" "P13693" "Q14103" "O15143" "P08133" "Q6P2E9" "P07947"
[113] "Q09028" "O14744" "P33176" "P40227" "O75937" "Q15717" "Q7L2H7" "O95373"
[121] "O95817" "Q14739" "Q8NF91" "P53992" "P35080" "P47755" "Q9Y262" "P25705"
[129] "P30041" "Q14203" "Q8WUM4" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[137] "P07951" "P53582" "P55060" "Q0ZGT2" "P60228" "P27348" "Q05048" "P78344"
[145] "Q04917" "P19525" "Q13409" "P33992" "Q01844" "Q63ZY3" "O15371" "Q92621"
[153] "P20073" "Q9Y6M1" "P12004" "Q04637" "Q96HS1" "P51114" "Q08J23" "O95793"
[161] "P61163" "P11586" "P17987" "Q13464" "Q9Y696" "O94901" "Q9Y3I0" "P20042"
[169] "Q06210" "P02511" "P42345" "Q14204" "Q8N684" "Q9UPN3" "P58107" "P04792"
[177] "Q9Y3F4" "P56192" "P10809" "P22626" "Q13425" "P50552" "Q99996" "Q9BXP5"
[185] "P18754" "O60684" "P06730" "P31948" "P26196" "P42224" "Q07866" "Q9NTI5"
[193] "O00151" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651" "P54577" "P61978"
[201] "P15924" "P23588" "P84103" "Q99700" "P60981" "Q7KZF4" "P62820" "Q92499"
[209] "P30153" "P09874" "P33991" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170"
[217] "Q14151" "Q9BUJ2" "P07900" "O75821" "Q9Y266" "P30626" "Q9NZI8" "P51991"
[225] "Q96I24" "Q92804" "Q9UNF1" "P50479" "P98194" "O15347" "Q9UKV8" "Q96QR8"
[233] "Q00577" "P55072" "P10599" "Q13200" "Q15056" "P62879" "P32322" "Q9NVI7"
[241] "P27816" "P46013" "Q07955" "Q99623" "P55795" "Q96EP5" "P52292" "P52948"
[249] "Q99729" "Q92879" "Q9NUL3" "Q99959" "P51812" "Q16630" "Q14011" "Q96HC4"
[257] "P31946" "Q92973" "O95819" "P54886" "Q86SQ0" "P02545" "P33993" "O75369"
[265] "Q14974" "Q15691" "O00425" "Q9Y2U8" "Q9BX66" "O00505" "P61586"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 141# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 1313# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 130# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 1694# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 6.7125, df = 1, p-value = 0.009574fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.008802
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
1.082362 1.809750
sample estimates:
odds ratio
1.39918 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("MSG", "Non-MSG"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
MSG 141 130
Non-MSG 1313 1694# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + MSG", "DE ~ MSG", "~ DE + MSG", "~ DE ~ MSG")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("Contingency Table Stacked Bar Chart") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 2. RNA Binding Proteins RPBs
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_RNAasprotein
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_RPB$Uniprot)
MSG_Exp [1] "O76021" "Q96PU8" "P67809" "P48634" "Q92522" "Q14694" "Q9NR30" "Q9P258"
[9] "Q9NZB2" "P16989" "Q9Y2X3" "Q53EP0" "Q9BQ39" "P62753" "P30876" "Q7Z739"
[17] "Q8NC51" "Q99459" "Q14966" "P61247" "P29558" "Q99873" "O00571" "Q71RC2"
[25] "P11940" "Q9H0S4" "Q16658" "Q13310" "Q9NR56" "P39019" "P63244" "Q9Y224"
[33] "Q14444" "Q13283" "P23396" "P19474" "P15880" "Q8WWM7" "O60832" "P62633"
[41] "Q96A72" "Q6PKG0" "P31483" "P51116" "Q5T8P6" "Q9BTD8" "Q92900" "Q92945"
[49] "P37108" "Q07666" "P55265" "P22087" "P55884" "P49458" "Q8IX01" "O60506"
[57] "P35637" "Q14152" "Q6PJT7" "P07305" "Q9NWB1" "Q15366" "Q9UBU9" "O75569"
[65] "Q8NCA5" "P22314" "P23246" "P15170" "Q14157" "Q7L2E3" "O15372" "P07737"
[73] "Q15233" "Q01085" "Q8ND56" "P13693" "Q14103" "P40227" "Q15717" "Q14739"
[81] "Q8NF91" "Q9Y262" "P25705" "P04083" "Q9UKF6" "Q13148" "O75534" "Q9Y6Q9"
[89] "P60228" "Q05048" "P78344" "P19525" "Q01844" "O15371" "Q9Y6M1" "Q04637"
[97] "P51114" "Q08J23" "O95793" "P17987" "Q9Y3I0" "P20042" "Q14204" "Q8N684"
[105] "Q9UPN3" "P58107" "P04792" "Q9Y3F4" "P10809" "P22626" "Q13425" "Q9BXP5"
[113] "P06730" "P31948" "P26196" "Q9UQ80" "P38646" "P49411" "Q8IXT5" "P09651"
[121] "P54577" "P61978" "P15924" "P23588" "P84103" "Q99700" "Q7KZF4" "Q92499"
[129] "P09874" "P27695" "Q8IX12" "Q01081" "Q06787" "Q08170" "Q14151" "Q9BUJ2"
[137] "P07900" "O75821" "Q9NZI8" "P51991" "Q96I24" "Q92804" "O15347" "Q9UKV8"
[145] "Q96QR8" "Q00577" "P55072" "P10599" "Q15056" "P62879" "P27816" "P46013"
[153] "Q07955" "P55795" "Q96EP5" "P52292" "P52948" "Q99729" "Q92879" "Q9NUL3"
[161] "Q16630" "Q14011" "Q92973" "P54886" "O75369" "Q14974" "Q15691" "O00425"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 85# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 1369# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 83# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 1741# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 2.5325, df = 1, p-value = 0.1115fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 0.1106
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.9426935 1.7994515
sample estimates:
odds ratio
1.302259 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("RPB", "Non-RPB"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
RPB 85 83
Non-RPB 1369 1741# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + RPB", "DE ~ RPB", "~ DE + RPB", "~ DE ~ RPB")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 3. Autophagy proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_RNAasprotein
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_Auto$Uniprot)
MSG_Exp [1] "Q99873" "O96013" "P15170" "Q01518" "P07947" "O95817" "P53992" "P19525"
[9] "Q96HS1" "P42345" "O60684" "P06730" "Q9UQ80" "P62820" "P30153" "P55072"
[17] "Q92879" "P51812"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 8# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 1446# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 10# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 1814# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.1962e-29, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.343264 2.832420
sample estimates:
odds ratio
1.003595 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("Autophagy", "Non-Autophagy"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
Autophagy 8 10
Non-Autophagy 1446 1814# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + Autophagy", "DE ~ Autophagy", "~ DE + Autophagy", "~ DE ~ Autophagy")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# 4. Heat Shock Proteins
#**************************
# All expressed proteins
Expressed_protein <- New_RNA_PRO_DF$uniprotswissprot
# Set I am testing
SAME_Sign_DE <- MSG_DE_RNAasprotein
# Intersection between MSG proteins and my expressed/detected proteins
MSG_Exp <- intersect(Expressed_protein, MSG_HSP$Uniprot)
MSG_Exp [1] "Q14694" "O00571" "P11940" "Q9NR56" "P31483" "P51116" "P37108" "Q9UN86"
[9] "P49458" "O60506" "P35637" "Q15366" "P17252" "P07737" "Q01085" "Q15717"
[17] "Q01844" "P51114" "Q13464" "P04792" "Q99996" "Q9UQ80" "P09651" "Q99700"
[25] "Q92499" "Q8IX12" "Q92804" "P55072" "P52292" "Q92879" "Q14011" "Q14974"
[33] "O00425" "O00505"# A = number of Test Set proteins that are in the MSG_Exp list
A <- intersect(SAME_Sign_DE$uniprotswissprot, MSG_Exp) %>% length()
A[1] 15# B = number of Test Set proteins that are not in the MSG_Exp list
B <- length(SAME_Sign_DE$uniprotswissprot) - A
B[1] 1439# C = number of expressed proteins that are in the MSG_Exp list but are not in Test Set proteins
C <- length(MSG_Exp) - A
C[1] 19# D = number of expressed proteins that are not in the MSG_Exp list and are not in Test Set proteins
D <- (nrow(New_RNA_PRO_DF) - length(SAME_Sign_DE$uniprotswissprot)) - C
D[1] 1805# Chi-Squared Test
mat <- matrix(c(A, B, C, D), nrow = 2)
chisq.test(mat)
Pearson's Chi-squared test with Yates' continuity correction
data: mat
X-squared = 1.3537e-27, df = 1, p-value = 1fisher.test(mat)
Fisher's Exact Test for Count Data
data: mat
p-value = 1
alternative hypothesis: true odds ratio is not equal to 1
95 percent confidence interval:
0.4665103 2.0647652
sample estimates:
odds ratio
0.9902736 table <- as.table(matrix(c(A, B, C, D), nrow = 2,
dimnames = list(Gene = c("HSP", "Non-HSP"),
Protein = c("DE", "Non-DE"))))
table Protein
Gene DE Non-DE
HSP 15 19
Non-HSP 1439 1805# Convert the table to a data frame
df_mat <- tidyr::gather(as.data.frame.matrix(table))
df_mat$key <- c("DE + HSP", "DE ~ HSP", "~ DE + HSP", "~ DE ~ HSP")
df_mat$Group <- c("DE", "DE", "~DE", "~DE")
# Create stacked bar chart
ggplot(df_mat, aes(x=Group, y=value, fill=key)) +
geom_bar(stat="identity") +
theme_minimal() +
ylab("Frequency") +
xlab("Category") +
ggtitle("") +
scale_fill_discrete(name="Key") +
theme(legend.position="bottom")
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
Subcellular Compartments
# Read in compartment data frames
Comp_Cytoplasm <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Cytoplasm.csv", header = TRUE)
Comp_Cytosol <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Cytosol.csv", header = TRUE)
Comp_ER <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Endoplasmic_Reticulum.csv", header = TRUE)
Comp_Endosome <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Endosome.csv", header = TRUE)
Comp_Golgi <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Golgi_apparatus.csv", header = TRUE)
Comp_Lysosome <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Lysosome.csv", header = TRUE)
Comp_membrane <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Membrane.csv", header = TRUE)
Comp_mitochondrion <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Mitochondrion.csv", header = TRUE)
Comp_Nucleus <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Nucleus.csv", header = TRUE)
Comp_Pbody <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Pbody.csv", header = TRUE)
Comp_Peroxisome <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Peroxisome.csv", header = TRUE)
Comp_Secreted <- read.csv(file = "/Users/omarjohnson/Documents/Projects/Dox_Proteomics/Data/Proteomics/Compartment_Summaries/New_Pro_RNA_DF_Compartments/ID_Secreted.csv", header = TRUE)####*——–All Protein Sets ####
list_input <- list(
Cytoplasm = Comp_Cytoplasm$Entry,
Cytosol = Comp_Cytosol$Entry,
ER = Comp_ER$Entry,
Endosome = Comp_Endosome$Entry,
Golgi = Comp_Golgi$Entry,
Lysosome = Comp_Lysosome$Entry,
Membrane = Comp_membrane$Entry,
Mitochondrion = Comp_mitochondrion$Entry,
Nucleus = Comp_Nucleus$Entry,
Pbody = Comp_Pbody$Entry,
Peroxisome = Comp_Peroxisome$Entry,
Secreted = Comp_Secreted$Entry
)# Upset Plots
upset(
fromList(list_input),
sets = names(list_input), # show all sets in the plot
order.by = "freq",
sets.bar.color = "#56B4E9",
matrix.color = "black",
main.bar.color = "#D55E00",
)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
# Convert to incidence matrix
matrix_input <- fromList(list_input)
matrix_input Cytoplasm Cytosol ER Endosome Golgi Lysosome Membrane Mitochondrion
1 1 0 1 0 0 0 1 0
2 1 0 0 0 0 0 0 0
3 1 0 0 0 0 0 0 0
4 1 0 0 0 0 0 1 0
5 1 0 1 0 0 0 1 1
6 1 1 0 0 0 0 1 0
7 1 0 0 0 0 0 0 0
8 1 1 0 0 0 0 0 0
9 1 0 0 0 0 0 1 0
10 1 0 1 0 0 0 1 0
11 1 0 0 0 0 0 0 0
12 1 0 0 0 0 0 0 0
13 1 0 0 0 0 0 0 0
14 1 1 0 0 1 0 1 1
15 1 0 1 0 1 0 1 0
16 1 0 0 0 0 0 1 0
17 1 0 0 0 0 0 0 1
18 1 1 0 0 0 0 0 0
19 1 0 1 0 0 0 1 0
20 1 0 0 0 1 0 1 0
21 1 0 0 0 1 0 1 0
22 1 0 1 0 0 0 1 0
23 1 0 0 0 1 0 0 0
24 1 0 0 0 0 0 1 1
25 1 0 0 0 0 0 0 0
26 1 0 0 0 0 0 1 0
27 1 0 0 0 0 0 1 0
28 1 0 0 0 0 0 0 1
29 1 0 0 0 0 0 0 0
30 1 0 0 0 0 0 0 0
31 1 0 0 0 0 0 0 0
32 1 0 0 0 0 0 0 0
33 1 0 0 0 0 0 0 0
34 1 0 0 0 0 0 0 0
35 1 0 0 0 0 0 0 0
36 1 0 0 0 0 0 0 1
37 1 0 0 0 0 0 0 0
38 1 0 0 0 0 0 1 1
39 1 0 0 0 0 0 0 0
40 1 1 0 0 1 0 1 0
41 1 0 1 0 0 0 1 0
42 1 0 0 0 0 0 0 0
43 1 1 0 0 0 0 0 0
44 1 0 1 0 0 0 0 0
45 1 0 0 0 0 0 0 0
46 1 0 0 0 0 0 0 0
47 1 0 0 0 0 0 1 0
48 1 0 0 0 1 0 0 1
49 1 0 0 0 0 0 1 0
50 1 0 0 0 0 0 0 0
51 1 0 1 0 0 0 0 0
52 1 0 0 0 0 0 0 0
53 1 0 0 0 1 0 1 0
54 1 0 0 0 0 0 0 0
55 1 0 0 0 0 0 0 0
56 1 0 0 0 0 0 1 0
57 1 0 0 0 0 0 0 0
58 1 0 0 0 0 0 0 0
59 1 0 0 0 0 0 0 0
60 1 0 0 0 0 0 1 0
61 1 0 0 0 0 0 1 0
62 1 1 0 0 0 0 1 0
63 1 0 1 0 0 0 0 0
64 1 0 1 0 0 0 1 0
65 1 0 0 1 0 0 1 0
66 1 0 0 0 0 0 1 0
67 1 1 0 0 1 0 1 0
68 1 0 0 0 0 0 0 0
69 1 0 0 0 0 0 0 0
70 1 0 0 0 0 0 0 0
71 1 0 0 0 0 0 0 0
72 1 0 0 0 0 0 1 0
73 1 0 0 0 0 0 1 0
74 1 0 0 0 1 0 0 0
75 1 0 0 0 0 0 0 0
76 1 0 0 0 0 0 0 0
77 1 0 1 1 0 0 1 0
78 1 0 0 0 0 0 0 0
79 1 0 0 1 0 0 1 0
80 1 0 0 0 0 0 0 0
81 1 0 0 0 0 0 0 0
82 1 0 0 0 0 0 0 0
83 1 0 1 0 0 0 1 0
84 1 0 0 0 0 0 0 0
85 1 1 0 0 0 0 0 0
86 1 0 0 0 0 0 0 0
87 1 0 0 0 0 0 0 0
88 1 0 1 0 0 0 0 0
89 1 1 1 0 0 0 1 0
90 1 0 0 0 0 0 1 0
91 1 1 0 0 0 0 0 1
92 1 1 1 0 0 0 1 0
93 1 0 0 0 0 0 0 0
94 1 0 0 0 0 0 0 0
95 1 0 0 0 0 0 1 0
96 1 1 1 0 0 0 0 0
97 1 1 1 0 0 0 1 0
98 1 0 0 0 0 0 0 1
99 1 0 0 0 0 0 0 0
100 1 0 1 0 0 0 0 0
101 1 0 0 0 0 0 0 0
102 1 0 0 0 0 0 0 0
103 1 0 0 0 0 0 0 1
104 1 1 0 0 0 0 1 1
105 1 0 0 0 0 0 0 1
106 1 0 0 0 0 0 0 0
107 1 0 1 0 0 0 1 0
108 1 0 0 0 0 0 0 0
109 1 0 1 0 0 0 1 1
110 1 0 0 0 0 0 0 1
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Nucleus Pbody Peroxisome Secreted
1 0 0 0 0
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2798 1 0 0 0
2799 1 0 0 0
2800 1 0 0 0
2801 1 0 0 0
2802 1 0 0 0
2803 1 0 0 0
2804 1 0 0 0
2805 1 0 0 0
2806 1 0 0 0
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2808 1 0 0 0
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2810 1 0 0 0
2811 1 0 0 0
2812 1 0 0 0
2813 1 0 0 0
2814 1 0 0 0
2815 1 0 0 0
2816 1 0 0 0
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2818 1 0 0 0
2819 1 0 0 0
2820 1 0 0 0
2821 1 0 0 0
2822 1 0 0 0
2823 1 0 0 0
2824 1 0 0 0
2825 1 0 0 0
2826 1 0 0 0
2827 1 0 0 0
2828 1 0 0 0
2829 1 0 0 0
2830 1 0 0 0
2831 1 0 0 0
2832 1 0 0 0
2833 1 0 0 0
2834 1 0 0 0
2835 1 0 0 0
2836 1 0 0 0
2837 1 0 0 0
2838 1 0 0 0
2839 1 0 0 0
2840 1 0 0 0
2841 1 0 0 0
2842 1 0 0 0
2843 1 0 0 0
2844 1 0 0 0
2845 1 0 0 0
2846 1 0 0 0
2847 1 0 0 0
2848 1 0 0 0
2849 1 0 0 0
2850 1 0 0 0
2851 1 0 0 0
2852 1 0 0 0
2853 1 0 0 0
2854 1 0 0 0
2855 1 0 0 0
2856 1 0 0 0
2857 1 0 0 0
2858 1 0 0 0
2859 1 0 0 0
2860 0 0 1 0
2861 0 0 1 0
2862 0 0 1 0
2863 0 0 1 0
2864 0 0 1 0
2865 0 0 1 0
2866 0 0 1 0
2867 0 0 0 1
2868 0 0 0 1
2869 0 0 0 1
2870 0 0 0 1
2871 0 0 0 1
2872 0 0 0 1
2873 0 0 0 1
2874 0 0 0 1
2875 0 0 0 1
2876 0 0 0 1
2877 0 0 0 1
2878 0 0 0 1
2879 0 0 0 1
2880 0 0 0 1
2881 0 0 0 1
2882 0 0 0 1
2883 0 0 0 1
2884 0 0 0 1
2885 0 0 0 1
2886 0 0 0 1
2887 0 0 0 1
2888 0 0 0 1
2889 0 0 0 1
2890 0 0 0 1
2891 0 0 0 1
2892 0 0 0 1
2893 0 0 0 1
2894 0 0 0 1
2895 0 0 0 1
2896 0 0 0 1
2897 0 0 0 1
2898 0 0 0 1
2899 0 0 0 1
2900 0 0 0 1
2901 0 0 0 1
2902 0 0 0 1
2903 0 0 0 1# common item row numbers across sets. Example: Cytoplasm and Cytosol (Code here is variable to interests)
common_items <- rownames(matrix_input)[matrix_input[,"Cytoplasm"] == 1 & matrix_input[,"Cytosol"] == 1]
# Unlist the lisst input
all_entries <- unlist(list_input)
# Get Uniprot IDs
common_items_names <- all_entries[as.numeric(common_items)]
common_items_names[length(common_items_names)]Cytoplasm998
"Q9Y6I9" # Venn
ggvenn(list_input)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
intersect(MSG_DE$uniprotswissprot, Comp_Cytoplasm$Entry) [1] "Q969Q1" "P17844" "P67809" "Q9BQG0" "P48634" "Q92841" "P78347" "Q00341"
[9] "Q13123" "Q14980" "Q14694" "Q9P258" "Q86XP3" "Q9NZB2" "P16989" "P08865"
[17] "P62906" "P62854" "P62750" "Q9UQB8" "P62753" "P62273" "Q99536" "P61254"
[25] "Q86U42" "P61313" "Q01780" "P46782" "Q9NQT5" "P62280" "P62701" "Q92747"
[33] "P36578" "P62888" "P49207" "Q7Z739" "Q8NC51" "P18621" "P46783" "P19338"
[41] "P53396" "Q99459" "Q9Y2I6" "P61513" "Q13509" "P62263" "P83731" "P62249"
[49] "P83881" "Q06830" "P08708" "P62269" "P62910" "P50914" "P61353" "P62841"
[57] "P61247" "P62857" "Q99873" "P62424" "P18077" "P06748" "Q8IWC1" "O00571"
[65] "P46778" "P32969" "P60510" "Q71RC2" "Q6P5Q4" "Q9H832" "P62851" "P62847"
[73] "P11940" "P62899" "Q16658" "Q13310" "Q9NR56" "Q12972" "P62917" "Q9Y3U8"
[81] "P39019" "P63244" "P46781" "P46776" "Q9NY33" "Q9BR76" "Q9BQ95" "Q9Y224"
[89] "O96013" "Q14444" "Q13283" "P23396" "P62244" "P19474" "P47914" "P60866"
[97] "Q14839" "O95433" "P39023" "P36873" "Q16555"####*--------DE proteins Upset ####
list_input <- list(
Cytoplasm = intersect(Comp_Cytoplasm$Entry, MSG_DE$uniprotswissprot) ,
Cytosol = intersect(Comp_Cytosol$Entry, MSG_DE$uniprotswissprot) ,
ER = intersect(Comp_ER$Entry, MSG_DE$uniprotswissprot) ,
Endosome = intersect(Comp_Endosome$Entry, MSG_DE$uniprotswissprot) ,
Golgi = intersect(Comp_Golgi$Entry , MSG_DE$uniprotswissprot) ,
Lysosome = intersect(Comp_Lysosome$Entry, MSG_DE$uniprotswissprot) ,
Membrane = intersect(Comp_membrane$Entry, MSG_DE$uniprotswissprot) ,
Mitochondrion = intersect(Comp_mitochondrion$Entry, MSG_DE$uniprotswissprot) ,
Nucleus = intersect(Comp_Nucleus$Entry, MSG_DE$uniprotswissprot) ,
Pbody = intersect(Comp_Pbody$Entry, MSG_DE$uniprotswissprot) ,
Peroxisome = intersect(Comp_Peroxisome$Entry, MSG_DE$uniprotswissprot) ,
Secreted = intersect(Comp_Secreted$Entry, MSG_DE$uniprotswissprot)
)
# Upset Plots
upset(
fromList(list_input),
sets = names(list_input), # show all sets in the plot
order.by = "freq",
sets.bar.color = "#56B4E9",
matrix.color = "black",
main.bar.color = "#D55E00",
)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####*——–Divergent proteins Upset ####
list_input <- list(
Cytoplasm = intersect(Comp_Cytoplasm$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Cytosol = intersect(Comp_Cytosol$Entry, MSG_DIVERGENT$uniprotswissprot) ,
ER = intersect(Comp_ER$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Endosome = intersect(Comp_Endosome$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Golgi = intersect(Comp_Golgi$Entry , MSG_DIVERGENT$uniprotswissprot) ,
Lysosome = intersect(Comp_Lysosome$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Membrane = intersect(Comp_membrane$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Mitochondrion = intersect(Comp_mitochondrion$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Nucleus = intersect(Comp_Nucleus$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Pbody = intersect(Comp_Pbody$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Peroxisome = intersect(Comp_Peroxisome$Entry, MSG_DIVERGENT$uniprotswissprot) ,
Secreted = intersect(Comp_Secreted$Entry, MSG_DIVERGENT$uniprotswissprot)
)
# Upset all members
upset(
fromList(list_input),
sets = names(list_input), # show all sets in the plot
order.by = "freq",
sets.bar.color = "#56B4E9",
matrix.color = "black",
main.bar.color = "#D55E00",
)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
####*——–DE Divergent proteins Upset ####
list_input <- list(
Cytoplasm = intersect(Comp_Cytoplasm$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Cytosol = intersect(Comp_Cytosol$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
ER = intersect(Comp_ER$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Endosome = intersect(Comp_Endosome$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Golgi = intersect(Comp_Golgi$Entry , MSG_DE_DIVERGENT$uniprotswissprot) ,
Lysosome = intersect(Comp_Lysosome$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Membrane = intersect(Comp_membrane$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Mitochondrion = intersect(Comp_mitochondrion$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Nucleus = intersect(Comp_Nucleus$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Pbody = intersect(Comp_Pbody$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Peroxisome = intersect(Comp_Peroxisome$Entry, MSG_DE_DIVERGENT$uniprotswissprot) ,
Secreted = intersect(Comp_Secreted$Entry, MSG_DE_DIVERGENT$uniprotswissprot)
)Upset all members
upset(
fromList(list_input),
sets = names(list_input), # show all sets in the plot
order.by = "freq",
sets.bar.color = "#56B4E9",
matrix.color = "black",
main.bar.color = "#D55E00",
)
| Version | Author | Date |
|---|---|---|
| 6534a9c | Omar-Johnson | 2023-09-14 |
sessionInfo()R version 4.2.0 (2022-04-22)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Big Sur/Monterey 10.16
Matrix products: default
BLAS: /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRblas.0.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/4.2/Resources/lib/libRlapack.dylib
locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
attached base packages:
[1] grid stats4 stats graphics grDevices utils datasets
[8] methods base
other attached packages:
[1] enrichplot_1.16.2
[2] ggvenn_0.1.10
[3] UpSetR_1.4.0
[4] DOSE_3.22.1
[5] clusterProfiler_4.4.4
[6] pheatmap_1.0.12
[7] qvalue_2.28.0
[8] Homo.sapiens_1.3.1
[9] TxDb.Hsapiens.UCSC.hg19.knownGene_3.2.2
[10] org.Hs.eg.db_3.15.0
[11] GO.db_3.15.0
[12] OrganismDbi_1.38.1
[13] GenomicFeatures_1.48.4
[14] AnnotationDbi_1.58.0
[15] biomaRt_2.52.0
[16] cluster_2.1.4
[17] ggfortify_0.4.16
[18] lubridate_1.9.2
[19] forcats_1.0.0
[20] stringr_1.5.0
[21] dplyr_1.1.2
[22] purrr_1.0.2
[23] readr_2.1.4
[24] tidyr_1.3.0
[25] tibble_3.2.1
[26] ggplot2_3.4.3
[27] tidyverse_2.0.0
[28] RColorBrewer_1.1-3
[29] RUVSeq_1.30.0
[30] edgeR_3.38.4
[31] limma_3.52.4
[32] EDASeq_2.30.0
[33] ShortRead_1.54.0
[34] GenomicAlignments_1.32.1
[35] SummarizedExperiment_1.26.1
[36] MatrixGenerics_1.8.1
[37] matrixStats_1.0.0
[38] Rsamtools_2.12.0
[39] GenomicRanges_1.48.0
[40] Biostrings_2.64.1
[41] GenomeInfoDb_1.32.4
[42] XVector_0.36.0
[43] IRanges_2.30.1
[44] S4Vectors_0.34.0
[45] BiocParallel_1.30.4
[46] Biobase_2.56.0
[47] BiocGenerics_0.42.0
[48] workflowr_1.7.1
loaded via a namespace (and not attached):
[1] utf8_1.2.3 R.utils_2.12.2 tidyselect_1.2.0
[4] RSQLite_2.3.1 scatterpie_0.2.1 munsell_0.5.0
[7] codetools_0.2-19 statmod_1.5.0 interp_1.1-4
[10] withr_2.5.0 colorspace_2.1-0 GOSemSim_2.22.0
[13] filelock_1.0.2 highr_0.10 knitr_1.43
[16] rstudioapi_0.15.0 labeling_0.4.2 git2r_0.32.0
[19] GenomeInfoDbData_1.2.8 hwriter_1.3.2.1 polyclip_1.10-4
[22] bit64_4.0.5 farver_2.1.1 rprojroot_2.0.3
[25] downloader_0.4 treeio_1.20.2 vctrs_0.6.3
[28] generics_0.1.3 xfun_0.40 timechange_0.2.0
[31] BiocFileCache_2.4.0 R6_2.5.1 graphlayouts_1.0.0
[34] locfit_1.5-9.8 bitops_1.0-7 cachem_1.0.8
[37] fgsea_1.22.0 gridGraphics_0.5-1 DelayedArray_0.22.0
[40] vroom_1.6.3 promises_1.2.1 BiocIO_1.6.0
[43] scales_1.2.1 ggraph_2.1.0 gtable_0.3.4
[46] processx_3.8.2 tidygraph_1.2.3 rlang_1.1.1
[49] splines_4.2.0 lazyeval_0.2.2 rtracklayer_1.56.1
[52] BiocManager_1.30.22 yaml_2.3.7 reshape2_1.4.4
[55] httpuv_1.6.11 RBGL_1.72.0 tools_4.2.0
[58] ggplotify_0.1.2 jquerylib_0.1.4 Rcpp_1.0.11
[61] plyr_1.8.8 progress_1.2.2 zlibbioc_1.42.0
[64] RCurl_1.98-1.12 ps_1.7.5 prettyunits_1.1.1
[67] deldir_1.0-9 viridis_0.6.4 cowplot_1.1.1
[70] ggrepel_0.9.3 fs_1.6.3 magrittr_2.0.3
[73] data.table_1.14.8 DO.db_2.9 reactome.db_1.81.0
[76] whisker_0.4.1 ggnewscale_0.4.9 aroma.light_3.26.0
[79] hms_1.1.3 patchwork_1.1.3 evaluate_0.21
[82] XML_3.99-0.14 jpeg_0.1-10 gridExtra_2.3
[85] compiler_4.2.0 shadowtext_0.1.2 crayon_1.5.2
[88] R.oo_1.25.0 htmltools_0.5.6 mgcv_1.9-0
[91] ggfun_0.1.2 later_1.3.1 tzdb_0.4.0
[94] aplot_0.2.0 ReactomePA_1.40.0 DBI_1.1.3
[97] tweenr_2.0.2 dbplyr_2.3.3 MASS_7.3-60
[100] rappdirs_0.3.3 Matrix_1.5-4.1 cli_3.6.1
[103] R.methodsS3_1.8.2 parallel_4.2.0 igraph_1.5.1
[106] pkgconfig_2.0.3 getPass_0.2-2 xml2_1.3.5
[109] ggtree_3.4.4 bslib_0.5.1 yulab.utils_0.0.8
[112] callr_3.7.3 digest_0.6.33 graph_1.74.0
[115] rmarkdown_2.24 fastmatch_1.1-4 tidytree_0.4.5
[118] restfulr_0.0.15 curl_5.0.2 graphite_1.42.0
[121] rjson_0.2.21 nlme_3.1-163 lifecycle_1.0.3
[124] jsonlite_1.8.7 viridisLite_0.4.2 fansi_1.0.4
[127] pillar_1.9.0 lattice_0.21-8 KEGGREST_1.36.3
[130] fastmap_1.1.1 httr_1.4.7 glue_1.6.2
[133] png_0.1-8 bit_4.0.5 ggforce_0.4.1
[136] stringi_1.7.12 sass_0.4.7 blob_1.2.4
[139] latticeExtra_0.6-30 memoise_2.0.1 ape_5.7-1